不对称合成

   

070303-有机化学

有机化学

2011-09--2016-07   中国科学院大连化学物理研究所   博士学位
2007-09--2011-06   湖南大学   学士学位

研究生

博士

   

2018-12~现在, 中国科学院大连化学物理研究所, 副研究员
2018-06~2018-12,中国科学院大连化学物理研究所, 助理研究员
2016-11~2018-01,美国伊利诺伊大学芝加哥分校, 博士后

   

[1] 周永贵, 白雨晴, 王新维, 吴波, 孙蕾. 一类基于环芳烷骨架的平面手性噁唑吡啶配体化合物及其合成方法和应用. CN: CN114685475A, 2022-07-01.

[2] 周永贵, 王新维, 李翔, 陈木旺, 吴波, 孙蕾. 一种包含有吲哚骨架的螺环的手性吲哚啉酮的合成方法. CN: CN115010565A, 2022-09-06.

[3] 吴波, 周永贵, 孙蕾. 一种钯催化不对称还原合成手性β-羟基酮的方法. CN: CN112574014B, 2022-03-11.

[4] 吴波, 周永贵, 孙蕾. 一种钯催化不对称还原合成手性β-羟基酮的方法. CN: CN112574014A, 2021-03-30.

[5] 周永贵, 谢焕平, 吴波, 孙蕾. 一种合成1,2-二氢苯并呋喃并吡啶化合物的方法. CN: CN112574223A, 2021-03-30.

[6] 周永贵, 王新维, 陈木旺, 吴波, 孙蕾. 一种手性磷酸催化合成含氟的手性缩酮胺的方法. CN: CN111848623B, 2021-11-12.

[7] 周永贵, 谢焕平, 吴波, 孙蕾. 一种合成手性杂三芳基甲烷的方法. CN: CN111662274A, 2020-09-15.

[8] 周永贵, 吴波, 陈木旺, 孙蕾. 一种合成手性3,4‑二氢香豆素的方法. CN: CN107474032A, 2017-12-15.

[9] 周永贵, 黄文学, 柳莲今, 吴波, 孙蕾. 一种铱催化氢化不对称合成哌嗪衍生物的方法. CN: CN106995413A, 2017-08-01.

[10] 周永贵, 陈木旺, 吴波, 陈章培, 孙蕾. 仿生催化不对称氢化合成手性含氟炔丙胺衍生物的方法. CN: CN106995377A, 2017-08-01.

[11] 周永贵, 严忠, 吴波, 高翔, 孙蕾. 一种钯催化亚胺膦酸酯不对称氢化合成手性胺基膦酸酯的方法. CN: CN106866730A, 2017-06-20.

[12] 周永贵, 黄文学, 吴波, 宋波, 陈木旺. 一种铱催化氢化合成3-哌啶酮衍生物的方法. CN: CN105693598A, 2016-06-22.

[13] 周永贵, 高翔, 吴波. 一类具有轴手性的联吡啶类配体及其合成方法. CN: CN113336764A, 2021-09-03.

[14] 周永贵, 高翔, 吴波. 一类具有轴手性的联吡啶配体及其合成方法. CN: CN105693737A, 2016-06-22.

[15] 周永贵, 罗京, 吴波, 陈木旺. 一种吲哚去芳构化合成取代环丙烷化合物的方法. CN: CN104803907A, 2015-07-29.

[16] 周永贵, 吴波, 陈木旺, 陈庆安. 一种合成2,3-二取代苯并二氢呋喃的方法. CN: CN104672247A, 2015-06-03.

[17] 周永贵, 高凯, 吴波, 余长斌, 时磊. 一种合成手性二氢-5H-吡咯并2,1-c1,4-苯并二氮杂卓的方法. CN: CN103288830A, 2013-09-11.

   

[1] Bai, YuQing, Wang, XinWei, Wu, Bo, Wang, XiaoQing, Liao, RongZheng, Li, Man, Zhou, YongGui. Design and Synthesis of Planar-Chiral Oxazole-Pyridine N,N-Ligands: Application in Palladium-Catalyzed Asymmetric Acetoxylative Cyclization. ACS CATALYSIS[J]. 2023, 13(14): 9829-9838, http://dx.doi.org/10.1021/acscatal.3c01163.
[2] Huang, WenJun, Chen, ZhiPeng, Liu, LiXia, Zhou, YongGui, Wu, Bo, Jiang, GuoFang. A facile synthesis of pyrrolo2,3-jphenanthridines via the cascade reaction of indoleanilines and aldehydes. JOURNAL OF HETEROCYCLIC CHEMISTRY[J]. 2022, 59(6): 1116-1122, http://dx.doi.org/10.1002/jhet.4444.
[3] Wang, Xiaoqing, Bai, Yuqing, Zhai, Xiaoyong, Wu, Bo, Zhou, Yonggui. Synthesis of poly(silyl ether)s via copper-catalyzed dehydrocoupling polymerization. CHINESE CHEMICAL LETTERS[J]. 2022, 33(5): 2639-2642, http://dx.doi.org/10.1016/j.cclet.2021.09.054.
[4] Wang, XiaoQing, Bai, YuQing, Wang, Kun, Wu, Bo, Zhou, YongGui. A metal-free and air-tolerable insertion polymerization using sulfoxonium ylides as monomers. EUROPEAN POLYMER JOURNAL[J]. 2022, 179: http://dx.doi.org/10.1016/j.eurpolymj.2022.111578.
[5] XiaoQing Wang, Bo Wu PhD, YuQing Bai, XiaoYong Zhai, YongGui Zhou PhD. CuH-catalyzed consecutive hydrosilylation/dehydrocoupling polymerization of difunctional hydroxyketones with dihydrosilanes for syntheses of chiral poly(silyl ether)s. EUROPEAN POLYMER JOURNAL. 2022, 177: http://dx.doi.org/10.1016/j.eurpolymj.2022.111474.
[6] Zhai, XiaoYong, Wang, XiaoQing, Wu, Bo, Zhou, YongGui. Copper-Catalyzed Si-H Bond Insertion Polymerization for Synthesis of Optically Active Polyesters Containing Silicon. CHINESE JOURNAL OF CHEMISTRY[J]. 2022, 40(1): 21-27, http://dx.doi.org/10.1002/cjoc.202100569.
[7] Wang, XinWei, Chen, MuWang, Wu, Bo, Wang, Baomin, Wan, Boshun, Zhou, YongGui. Chiral phosphoric acid-catalyzed regioselective synthesis of spiro aminals with quaternary stereocenters. TETRAHEDRON LETTERS[J]. 2021, 65: http://dx.doi.org/10.1016/j.tetlet.2020.152793.
[8] Wang, XinWei, Li, Xiang, Chen, MuWang, Wu, Bo, Zhou, YongGui. Chiral Phosphoric Acid-Catalyzed Pictet-Spengler Reactions for Synthesis of 5 ',11 '-Dihydrospiroindoline-3,6 '-indolo3,2-cquinolin-2-ones Containing Quaternary Stereocenters. JOURNAL OF ORGANIC CHEMISTRY[J]. 2021, 86(9): 6897-6906, http://dx.doi.org/10.1021/acs.joc.1c00289.
[9] Huang, WenJun, Ma, YaYa, Liu, LiXia, Wu, Bo, Jiang, GuoFang, Zhou, YongGui. Chiral Phosphoric Acid-Catalyzed C6 Functionalization of 2,3-Disubstituted Indoles for Synthesis of Heterotriarylmethanes. ORGANIC LETTERS[J]. 2021, 23(7): 2393-2398, http://dx.doi.org/10.1021/acs.orglett.0c04002.
[10] Zhao, ZiBiao, Li, Xiang, Wu, Bo, Zhou, YongGui. Biomimetic Asymmetric Reduction of Quinazolinones with Chiral and Regenerable NAD(P)H Models. CHINESE JOURNAL OF CHEMISTRY[J]. 2020, 38(7): 714-718, http://lib.cqvip.com/Qikan/Article/Detail?id=7102778939.
[11] Zhao, ZiBiao, Li, Xiang, Chen, MuWang, Wu, Bo, Zhou, YongGui. Enantioselective Synthesis of Tetrahydroquinolines via One-Pot Cascade Biomimetic Reduction. CHINESE JOURNAL OF CHEMISTRY[J]. 2020, 38(12): 1691-1695, http://lib.cqvip.com/Qikan/Article/Detail?id=7103704700.
[12] Wang, XiaoQing, Zhai, XiaoYong, Wu, Bo, Bai, YuQing, Zhou, YongGui. Synthesis of Chiral Poly(silyl ether)s via CuH-Catalyzed Asymmetric Hydrosilylation Polymerization of Diketones with Silanes. ACS MACRO LETTERS[J]. 2020, 9(7): 969-973, https://www.webofscience.com/wos/woscc/full-record/WOS:000555009000009.
[13] 谢焕平, 吴波, 陈木旺, 余长斌, 黎红旺, 李翔, 周永贵. 方酰胺催化氮杂二烯和吡唑啉-5-酮的加成：含吡唑三芳基甲烷的不对称合成. 有机化学[J]. 2020, 40(10): 3452-3462, http://lib.cqvip.com/Qikan/Article/Detail?id=7103355116.
[14] Xie, Huanping, Wu, Bo, Chen, Muwang, Yu, Changbin, Li, Hongwang, Li, Xiang, Zhou, Yonggui. Enantioselective Synthesis of Triarylmethanes Bearing Pyrazole Moiety through Squaramide-Catalyzed Addition of Azadienes with Pyrazolin-5-ones. CHINESE JOURNAL OF ORGANIC CHEMISTRY[J]. 2020, 40(10): 3452-3462, http://dx.doi.org/10.6023/cjoc202003005.
[15] Li, Xiang, Zhao, ZiBiao, Chen, MuWang, Wu, Bo, Wang, Han, Yu, ChangBin, Zhou, YongGui. Palladium-catalyzed asymmetric hydrogenation of 2-aryl cyclic ketones for the synthesis of trans cycloalkanols through dynamic kinetic resolution under acidic conditions. CHEMICAL COMMUNICATIONS[J]. 2020, 56(43): 5815-5818, https://www.webofscience.com/wos/woscc/full-record/WOS:000537959100019.
[16] Zhu, ZhouHao, Ding, YiXuan, Wu, Bo, Zhou, YongGui. Design and synthesis of chiral and regenerable 2.2paracyclophane-based NAD(P)H models and application in biomimetic reduction of flavonoids. CHEMICAL SCIENCE[J]. 2020, 11(37): 10220-10224, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162316/.
[17] Xie, HuanPing, Sun, Lei, Wu, Bo, Zhou, YongGui. Copper-Catalyzed Alkynylation/Cyclization/Isomerization Cascade for Synthesis of 1,2-Dihydrobenzofuro3,2-bpyridines and Benzofuro3,2-bpyridines. JOURNAL OF ORGANIC CHEMISTRY[J]. 2019, 84(23): 15498-15507, https://www.webofscience.com/wos/woscc/full-record/WOS:000502170600045.
[18] Wang, XinWei, Chen, MuWang, Wu, Bo, Wang, Baomin, Zhou, YongGui. Chiral Phosphoric Acid-Catalyzed Synthesis of Fluorinated 5,6-Dihydroindolo1,2-cquinazolines with Quaternary Stereocenters. JOURNAL OF ORGANIC CHEMISTRY[J]. 2019, 84(12): 8300-8308, [19] HuanPing Xie, Bo Wu, XinWei Wang, YongGui Zhou. Chiral Brønsted acid-catalyzed conjugate addition of indoles to azadienes: Enantioselective synthesis of hetero-triarylmethanes. CHINESE JOURNAL OF CATALYSIS. 2019, 1566-1575, http://dx.doi.org/10.1016/S1872-2067(19)63396-6.
[20] Shen, HongQiang, Wu, Bo, Xie, HuanPing, Zhou, YongGui. Preparation of Axially Chiral 2,2 '-Biimidazole Ligands through Remote Chirality Delivery and Their Application in Asymmetric Carbene Insertion into N-H of Carbazoles. ORGANIC LETTERS[J]. 2019, 21(8): 2712-2717, http://cas-ir.dicp.ac.cn/handle/321008/165496.
[21] Zhao, Yang, Wang, Han, Wu, Bo, Zhou, YongGui. Synthesis of paracyclophanes with planar and central chirality: kinetic resolution of 2.2paracyclophane aldimines via palladium-catalyzed addition of arylboronic acids. ORGANIC CHEMISTRY FRONTIERS[J]. 2019, 6(24): 3956-3960, [22] Bo Wu, Selwyn S Jayakar, Xiaojuan Zhou, Katherine Titterton, David C Chiara, Andrea L Szabo, Pavel Y Savechenkov, Daniel E Kent, Jonathan B Cohen, Stuart A Forman, Keith W Miller, Karol S Bruzik. Inhibitable photolabeling by neurosteroid diazirine analog in the β3-Subunit of human hetereopentameric type A GABA receptors. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2019, 162: 810-824, http://dx.doi.org/10.1016/j.ejmech.2018.11.019.
[23] Gu, Zheng, Wu, Bo, Jiang, GuoFang, Zhou, YongGui. Synthesis of Benzofuran-fused 1,4-Dihydropyridines via Bifunctional Squaramide-catalyzed Formal 4+2 Cycloaddition of Azadienes with Malononitrile. CHINESE JOURNAL OF CHEMISTRY[J]. 2018, 36(12): 1130-1134, http://lib.cqvip.com/Qikan/Article/Detail?id=6100154713.
[24] HuanPing Xie, Zhong Yan, Bo Wu, ShuBo Hu, YongGui Zhou. Synthesis of electron-deficient (Sa,R,R)-(CF3)2-C3-TunePhos and its applications in asymmetric hydrogenation of α-iminophosphonates. TETRAHEDRON LETTERS. 2018, 59(31): 2960-2964, http://dx.doi.org/10.1016/j.tetlet.2018.06.037.
[25] 吴波. Regioselective a-Addition of Deconjugated Butenolides: Enantioselective Synthesis of Dihydrocoumarins. Angew. Chem. Int. Ed.. 2017, [26] Gao, Xiang, Wu, Bo, Yan, Zhong, Zhou, YongGui. Enantioselective palladium-catalyzed arylation of N-tosylarylimines with arylboronic acids using a chiral 2,2 '-bipyridine ligand. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2016, 14(1): 55-58, http://cas-ir.dicp.ac.cn/handle/321008/171560.
[27] Chen, MuWang, Wu, Bo, Chen, ZhangPei, Shi, Lei, Zhou, YongGui. Synthesis of Chiral Fluorinated Propargylamines via Chemoselective Biomimetic Hydrogenation. ORGANIC LETTERS[J]. 2016, 18(18): 4650-4653, http://cas-ir.dicp.ac.cn/handle/321008/170182.
[28] Yan, Zhong, Wu, Bo, Gao, Xiang, Zhou, YongGui. Enantioselective synthesis of quaternary alpha-aminophosphonates by Pd-catalyzed arylation of cyclic alpha-ketiminophosphonates with arylboronic acids. CHEMICAL COMMUNICATIONS[J]. 2016, 52(72): 10882-10885, http://cas-ir.dicp.ac.cn/handle/321008/170114.
[29] Huang, WenXue, Liu, LianJin, Wu, Bo, Feng, GuangShou, Wang, Baomin, Zhou, YongGui. Synthesis of Chiral Piperazines via Hydrogenation of Pyrazines Activated by Alkyl Halides. ORGANIC LETTERS[J]. 2016, 18(13): 3082-3085, http://cas-ir.dicp.ac.cn/handle/321008/170364.
[30] 高翔, 吴波, 黄文学, 陈木旺, 周永贵. Enantioselective Palladium-Catalyzed C¢H Functionalization of Indoles Using an Axially Chiral 2,2’-Bipyridine Ligand. ANGEWANDTE CHEMIE INTERNATIONAL EDITION[J]. 2016, 54: 11956-, http://cas-ir.dicp.ac.cn/handle/321008/148000.
[31] Yan, Zhong, Wu, Bo, Gao, Xiang, Chen, MuWang, Zhou, YongGui. Enantioselective Synthesis of alpha-Amino Phosphonates via Pd-Catalyzed Asymmetric Hydrogenation. ORGANIC LETTERS[J]. 2016, 18(4): 692-695, http://cas-ir.dicp.ac.cn/handle/321008/171278.
[32] Gao, Xiang, Wu, Bo, Yan, Zhong, Zhou, YongGui. Copper-catalyzed enantioselective C-H functionalization of indoles with an axially chiral bipyridine ligand. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2016, 14(35): 8237-8240, http://www.corc.org.cn/handle/1471x/2376159.
[33] 陈木旺, 叶智识, 陈章培, 吴波, 周永贵. Enantioselective Synthesis of Trifluoromethyl Substituted Piperidines with Multiple Stereogeni Centers via Hydrogenation of Pyridinium Hydrochlorides. ORGANIC CHEMISTRY FRONTIERS有机化学前沿[J]. 2015, 2: 586-, http://cas-ir.dicp.ac.cn/handle/321008/148058.
[34] Peng, Libo, Yang, Limin, Wu, Nan, Wu, Bo. Primary primitive neuroectodermal tumor arising in the mesentery and ileocecum: A report of three cases and review of the literature. EXPERIMENTAL AND THERAPEUTIC MEDICINE[J]. 2015, 9(4): 1299-1303, https://www.webofscience.com/wos/woscc/full-record/WOS:000351711600034.
[35] Chen, MuWang, Ye, ZhiShi, Chen, ZhangPei, Wu, Bo, Zhou, YongGui. Enantioselective synthesis of trifluoromethyl substituted piperidines with multiple stereogenic centers via hydrogenation of pyridinium hydrochlorides. ORGANIC CHEMISTRY FRONTIERS[J]. 2015, 2(5): 586-589, https://www.webofscience.com/wos/woscc/full-record/WOS:000364445300023.
[36] 吴波, 陈木旺, 周永贵. A streamlined Synthesis of 2,3-Dihydrobenzofurans via the o-Quinone Methides Intermediates. 24th international society of heterocyclic chemistry congressnull. 2013, 141-, http://159.226.238.44/handle/321008/120085.
[37] Zhang, Min, Lin, Guoqiang, Wu, Bo, Shao, Zhigang. Composition optimization of arc ion plated CrNx films on 316L stainless steel as bipolar plates for polymer electrolyte membrane fuel cells. JOURNAL OF POWER SOURCES[J]. 2012, 205(1): 318-323, http://dx.doi.org/10.1016/j.jpowsour.2012.01.056.

   

（ 1 ） 中国科学院大连化学物理 研究所优秀青年博士人才, 主持, 市地级, 2019-06--2022-06
（ 2 ） 醇质子作为氢源的不对称还原, 主持, 国家级, 2020-01--2022-12
（ 3 ） 金属催化硅氢化聚合合成手性聚硅醚, 主持, 市地级, 2020-08--2022-07

现指导学生

陈简  硕士研究生  070303-有机化学