070304-物理化学（含：化学物理）
070303-有机化学

不对称催化,催化化学

1994-09--1997-09   中科院兰州化物所   博士
1987-09--1990-06   兰州大学   硕士
1983-09--1987-06   西北师范大学化学系   学士

-- 研究生

-- 博士

   

2004-01~2016-12,中科院兰州化物所, 研究员
2001-02~2003-08,香港理工大学, 副教授
1997-09~2001-02,中科院兰州化物所, 副研究员
1990-06~1994-06,中科院兰州化物所, 研实员和助理研究员

   

（1） 不对称催化羰化和氢化反应研究, 二等奖, 省级, 1999

（ 1 ） 不对称羰化法合成手性功能高分子聚酮的方法, 发明, 2009, 第 1 作者, 专利号: ZL200510048322.4
（ 2 ） 木质素磺酸盐接枝共聚物化学固沙剂制备方法, 发明, 2010, 第 1 作者, 专利号: ZL200710188572.7
（ 3 ） 一种高分子材料化学固沙剂的制备方法, 发明, 2011, 第 1 作者, 专利号: ZL200810150285.1
（ 4 ） 酰胺羰化反应合成N-酰基苯基甘氨酸的方法, 发明, 2011, 第 1 作者, 专利号: ZL200610104993.2
（ 5 ） 酰胺羰化反应合成N-乙酰基-1-苯基甘氨酸的方法, 发明, 2012, 第 1 作者, 专利号: ZL200810150288.5
（ 6 ） 一种化学固沙剂, 发明, 2013, 第 1 作者, 专利号: ZL200910117687.6
（ 7 ） 酒石酸衍生的手性亚磷酸酯配体及其合成方法与用途, 发明, 2012, 第 1 作者, 专利号: 201210340249.8
（ 8 ） 一种取代环己醇的合成方法, 发明, 2014, 第 1 作者, 专利号: 201410227169.0
（ 9 ） 一种木质素接枝共聚物的制备方法, 发明, 2013, 第 1 作者, 专利号: 201310506131.2
（ 10 ） 手性双齿亚磷酸酯配体及其制备方法与用途, 发明, 2013, 第 1 作者, 专利号: 201310686020.4
（ 11 ） 钯/亚磷酸酯配体催化不对称烯丙基烷化反应的方法, 发明, 2014, 第 1 作者, 专利号: 201410450880.2
（ 12 ） 一种负载型催化剂及其制备方法和应用, 发明, 2014, 第 1 作者, 专利号: 201410845138.1
（ 13 ） 环己二醇衍生的手性双齿亚磷酸酯配体及其制备方法和应用, 发明, 2014, 第 1 作者, 专利号: 201410785924.7
（ 14 ） 甘露醇衍生的手性双齿亚磷酸酯配体及其制备方法与用途, 发明, 2015, 第 1 作者, 专利号: ZL201010551598.5
（ 15 ） 酒石酸衍生的手性双齿亚磷酸酯配体制备方法和用途, 发明, 2016, 第 1 作者, 专利号: ZL201210340249.8
（ 16 ） 一种环己酮或取代环己酮的制备方法, 发明, 2015, 第 1 作者, 专利号: 201510029698.4
（ 17 ） 一种环己酮或取代环己酮的合成方法, 发明, 2016, 第 1 作者, 专利号: ZL201510029698.4

   

[1] 郑治文, 王来来. 苯乙烯与4-氨基苯酚的氢氨甲基化反应研究. Journal of Molecular Catalysis (China)[J]. 2022, 36(6): 513-521, [2] 张荣慧, 闵灯, 王来来, 谢文健. 气相氟化合成氢氟烯烃催化剂的研究进展. 高等学校化学学报[J]. 2020, 41(10): 12-, http://lib.cqvip.com/Qikan/Article/Detail?id=7102912795.
[3] Lailai Wang. Highly selective synthesis of trans-1-chloro-3, 3, 3-trifluoropropene by the vapor fluorination of 1, 1, 3, 3-tetrachloropropene with HF over the chromium oxide-based catalysts. Journal of molecular catalysis (China). 2020, [4] 郑治文, 张荣慧, 王来来, 谢文健. 合成偏氟乙烯和含氟丙烯的催化剂及应用研究进展. 分子催化[J]. 2019, 33(3): 285-295, http://lib.cqvip.com/Qikan/Article/Detail?id=7002508277.
[5] Lailai Wang. Rh/Phosphine Catalyzed Efficient Hydroaminomethylation of Heterocyclic and/or Cyclic olefins with Amines. synthesis. 2019, [6] Tian, Mi, Li, Haifeng, Wang, Lailai. Highly efficient Rh(I)/tris-H-8-binaphthyl monophosphite catalysts for hydroformylation of dicyclopentadiene to dialdehydes. CHINESE JOURNAL OF CATALYSIS[J]. 2018, 39(10): 1646-1652, http://dx.doi.org/10.1016/S1872-2067(18)63098-0.
[7] Li, Haifeng, Wang, Lailai. A novel and practical method for the synthesis of dinotefuran through Michael addition of nitromethane to diethyl maleate. TETRAHEDRON[J]. 2018, 74(2): 336-340, http://dx.doi.org/10.1016/j.tet.2017.12.002.
[8] Lailai Wang. Asymmetric allylic alkylation and hydrogenation with transition metal complexes of diphosphite ligands based on (1S,2S)- and / or (1R,2R) -trans-1,2-cyclohexanediol. Catal. Lett.. 2017, [9] Lailai Wang. The novel MOP-type H8-binaphthyl monodentate phosphite ligands and their application in transition metal-catalyzed asymmetric 1,4-conjugate addition and hydroformylation. Tetronhydron Asymmetric. 2017, [10] Pang, ZengBo, Tian, Mi, Li, HaiFeng, Wang, LaiLai. The Cu-catalyzed asymmetric conjugate addition with chiral diphosphite ligands derived from D-(-)-tartaric acid. SYNTHETIC COMMUNICATIONS[J]. 2017, 47(6): 618-627, http://www.irgrid.ac.cn/handle/1471x/1180984.
[11] Lailai Wang. Palladium/TiN Nanocomposite Catalyst for selective hydrogenation of phenol and its derivatives. Chin. Chem. Lett.. 2016, [12] Pang, ZengBo, Li, HaiFeng, Wang, LaiLai. Synthesis of novel cyclohexanediol-derived chiral phosphite ligands and their application in the Cu-catalyzed conjugate addition of organozinc to cyclic enones. CHINESE CHEMICAL LETTERS[J]. 2016, 27(2): 271-276, http://dx.doi.org/10.1016/j.cclet.2015.10.009.
[13] 田密, 王来来. 过渡金属/磷配体络合物催化不对称氢甲酰化研究进展. 云南民族大学学报：自然科学版[J]. 2016, 25(2): 98-106, http://lib.cqvip.com/Qikan/Article/Detail?id=668233683.
[14] Li, Haifeng, Pang, Zengbo, Gao, Ping, Wang, Lailai. Fe(III)-catalyzed grafting copolymerization of lignin with styrene and methyl methacrylate through AGET ATRP using triphenyl phosphine as a ligand. RSC ADVANCES[J]. 2015, 5(67): 54387-54394, http://www.irgrid.ac.cn/handle/1471x/972373.
[15] Pang, Zengbo, Li, Haifeng, Tian, Mi, Wang, Lailai. Chiral diphosphites derived from (1R,2R)-trans-1,2-cyclohexanediol: a new class of ligands for asymmetric hydrogenations. TETRAHEDRON-ASYMMETRY[J]. 2015, 26(24): 1389-1393, http://dx.doi.org/10.1016/j.tetasy.2015.10.020.
[16] Li, Haifeng, Zhang, Qinsheng, Gao, Ping, Wang, Lailai. Preparation and characterization of graft copolymer from dealkaline lignin and styrene. JOURNAL OF APPLIED POLYMER SCIENCE[J]. 2015, 132(17): http://www.irgrid.ac.cn/handle/1471x/972372.
[17] 王来来. 基于ATRP接枝改性木质素的研究进展. 高分子学报. 2015, [18] Pang Zengbo, Xing Aiping, Wang Lailai. Synthesis of Novel Tartaric Acid-derived Chiral Phosphite Ligands and Their Application in the Cu-catalyzed Conjugate Addition of Diethylzinc to Cyclic Enones. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES[J]. 2015, 31(5): 756-760, http://lib.cqvip.com/Qikan/Article/Detail?id=666297006.
[19] Choy, Pui Ying, Luk, Kwan Chak, Wu, Yinuo, So, Chau Ming, Wang, Lailai, Kwong, Fuk Yee. Regioselective Direct C-3 Arylation of Imidazo1,2-apyridines with Aryl Tosylates and Mesylates Promoted by Palladium-Phosphine Complexes. JOURNAL OF ORGANIC CHEMISTRY[J]. 2015, 80(3): 1457-1463, http://www.irgrid.ac.cn/handle/1471x/1002828.
[20] Zhang, Qinsheng, Li, Haifeng, Gao, Ping, Wang, Lailai. PVP-NiB amorphous catalyst for selective hydrogenation of phenol and its derivatives. CHINESE JOURNAL OF CATALYSIS[J]. 2014, 35(11): 1793-1799, http://dx.doi.org/10.1016/S1872-2067(14)60203-5.
[21] Lailai Wang. Efficient novel 1, 2- diphosphite ligands derived from D-manntiol in the Pd-catalysed asymmetric allylic alkylation. TETRAHEDRON. 2014, [22] 王来来. D-甘露醇衍生的手性磷配体：合成及应用于铑催化α-脱氢氨基酸酯不对称氢化. Journal of molecular catalysis (China). 2014, [23] 张勤生, 李海峰, 王来来. 酚类衍生物催化加氢合成酮和醇的研究进展. 分子催化[J]. 2014, 574-580, http://lib.cqvip.com/Qikan/Article/Detail?id=70906772504849524854484949.
[24] 苗晓, 王来来. 过渡金属/磷配体催化不对称氢化反应研究进展. 分子催化[J]. 2014, 282-293, http://lib.cqvip.com/Qikan/Article/Detail?id=70906772504849524851484952.
[25] Xing, Aiping, Bai, Caibing, Wang, Lailai. Chiral phosphite ligands derived from L-(+)-tartaric acid: synthesis and application in the Cu-catalyzed 1,4-conjugate addition of organozincs to cyclic enones. TETRAHEDRON[J]. 2013, 69(2): 455-459, http://dx.doi.org/10.1016/j.tet.2012.11.038.
[26] 张勤生, 王来来. 木质素及其模型化合物的加氢脱氧反应研究进展. 分子催化[J]. 2013, 27(1): 89-97, http://www.irgrid.ac.cn/handle/1471x/743413.
[27] Zhao, QingLu, Miao, Xiao, Wang, LaiLai. Enantioselective hydrogenation of functionalized olefins catalyzed by Rh-chiral bidentatephosphite complexes. TETRAHEDRON-ASYMMETRY[J]. 2013, 24(2-3): 104-107, http://dx.doi.org/10.1016/j.tetasy.2012.12.001.
[28] 赵水侠, 王来来. NaBH4/I2催化加氢裂解木质素的研究. 分子催化[J]. 2012, 26(2): 105-110, http://lib.cqvip.com/Qikan/Article/Detail?id=41755136.
[29] Lailai Wang. Hydrogenolysis of alkaline lignin catalyzed by using metal complex and triphenyl phosphine. 分子催化. 2012, [30] 邢爱萍, 王来来, Kwok Waihim. 溴化钯或乙酰丙酮羰基铑/手性配体催化醛与乙酰胺的不对称酰胺羰化反应研究. 分子催化[J]. 2011, 25(3): 202-208, http://lib.cqvip.com/Qikan/Article/Detail?id=38332060.
[31] Wang Lailai, Zhang Qinsheng, Cui Yuming. One-step synthesis of chiral dimethyl 2-oxo-3-phenyl-glutarate in the asymmetric Triple-carbonylation of styrene. CHIN. J. CATAL.[J]. 2011, 32: 1143-1148, http://dx.doi.org/10.1016/S1872-2067(10)60253-7.
[32] 王来来. 手性磷酸酯配体的设计合成及其在不对称加氢中的应用研究进展. 《分子催化》. 2011, [33] Wang Lailai, Jia Xiaojing, Wan Bo. Synthesis of chiral functionalized polymers by alternating copolymerization of propene and CO using the Pd(OAc)2/(S)-P-PHOS catalyst. CHIN. J. CATAL.[J]. 2011, 32: 65-69, http://dx.doi.org/10.1016/S1872-2067(10)60161-1.
[34] Wan Bo, Fuk Yee Kwong, Wang Lailai, Xu Lijin, Zhao Qinglu, Xing Aiping. New chiral monophosphite ligands containing BINOL and/or H8-BINOL bearing adamantyl substituents: effect of ligand scaffold on the enantioselective 1,4-conjugate addition of diethylzinc to cyclic enones. CHIN. J. CATAL.[J]. 2011, 32: 80-85, http://dx.doi.org/10.1016/S1872-2067(10)60164-7.
[35] Zhao, QingLu, Wang, LaiLai. Synthesis of novel chiral bidentatephosphite ligands derived from the pyranoside backbone of monosaccharides and their application in the Cu-catalyzed conjugate addition of dialkylzinc to enones. TETRAHEDRON-ASYMMETRY[J]. 2011, 22(20-22): 1885-1890, http://dx.doi.org/10.1016/j.tetasy.2011.11.003.
[36] 邢爱萍, 王来来. 糖骨架手性配体合成及应用于不对称催化反应研究进展. 分子催化[J]. 2011, 25(2): 180-190, http://lib.cqvip.com/Qikan/Article/Detail?id=37561829.
[37] 赵水侠, 王来来. 有机硅氧烷预聚体的合成及其在化学固沙中的应用. 应用化学[J]. 2011, 28(7): 753-758, http://lib.cqvip.com/Qikan/Article/Detail?id=38433597.
[38] Qing-Lu Zhao, Lai-Lai Wang, Ai-Ping Xing. Synthesis of novel diphosphite ligands derived from d-mannitol and their application in Cu-catalyzed enantioselective conjugate addition of organozinc to enones. TETRAHEDRON: ASYMMETRY[J]. 2010, 21(24): 2993-2998, http://dx.doi.org/10.1016/j.tetasy.2010.12.009.
[39] Zhao, QingLu, Tse, Man Kin, Wang, LaiLai, Xing, AiPing, Jiang, Xianxing. Synthesis of diphosphite ligands derived from glucopyranoside and their application in the Cu-catalyzed asymmetric 1,4-addition of organozinc to enones. TETRAHEDRON-ASYMMETRY[J]. 2010, 21(23): 2788-2793, http://dx.doi.org/10.1016/j.tetasy.2010.11.012.
[40] Cui, Yuming, Wang, Lailai, Kwong, Fuk Yee, Tse, Man Kin, Chan, Albert S C. A Highly Efficient Chiral-Bridged Diphosphine Ligand Modified Cationic Palladium(II) Catalyst System for Asymmetric Alternating Copolymerization of Propene and Carbon Monoxide. SYNLETT[J]. 2009, 2696-2700, http://www.corc.org.cn/handle/1471x/2404612.
[41] Zhao Qinglu, Yang Min, Wang Lailai. Efficient ligand-free, palladium-catalyzed amidocarbonylation in ionic liquids: Facile synthesis of N-acyl-a-arylglycines. SYNTHETIC COMMUNICATIONS[J]. 2008, 38: 4460-4473, http://www.irgrid.ac.cn/handle/1471x/521021.
[42] 贾小静, 王来来, 陈新滋, 李月明. 葡萄糖及半乳糖衍生的手性双膦-铑（Ⅰ）配合物催化苯乙烯不对称氢甲酰化反应. 催化学报[J]. 2007, 28(6): 492-494, http://lib.cqvip.com/Qikan/Article/Detail?id=24815233.
[43] Zhao, QingLu, Wang, LaiLai, Kwong, Fuk Yee, Chan, Albert S C. Cu-catalyzed enantioselective conjugate addition of diethylzinc to cyclic enones with chiral phosphite ligands derived from 1,2 : 5,6-di-O-cyclohexylidene-D-mannitol. TETRAHEDRON-ASYMMETRY[J]. 2007, 18(16): 1899-1905, http://dx.doi.org/10.1016/j.tetasy.2007.07.008.
[44] Wang, HJ, Wang, LL, Lam, WS, Yu, WY, Chan, ASC. Pd-catalyzed asymmetric alternating co-polymerization of propene with carbon monoxide using ionic liquids. TETRAHEDRON-ASYMMETRY[J]. 2006, 17(1): 7-11, http://dx.doi.org/10.1016/j.tetasy.2005.11.030.
[45] Wang, LL, Guo, RW, Li, YM, Chan, ASC. Rhodium-catalyzed asymmetric hydroformylation of vinylarenes with novel chiral P,N-ligands derived from 1,2 : 5,6-di-O-cyclohexylidene-D-mannitol. TETRAHEDRON-ASYMMETRY[J]. 2005, 16(19): 3198-3204, http://dx.doi.org/10.1016/j.tetasy.2005.08.040.
[46] Wang, LL, Li, YM, Yip, CW, Qiu, LQ, Zhou, ZY, Chan, ASC. Synthesis of new chiral aryl diphosphite ligands derived from pyranoside backbone of monosacharides and their application in copper-catalyzed asymmetric conjugate addition of diethylzinc to cyclic enones. ADVANCED SYNTHESIS & CATALYSIS[J]. 2004, 346(8): 947-953, https://www.webofscience.com/wos/woscc/full-record/WOS:000223438200013.

（ 1 ） 不对称催化反应进展(其中二篇论文）, The advance of asymmetric catalysis, 科学出版社, 2000-06, 第 1 作者

   

（ 1 ） 三氯乙酰氯和丙烯腈一步法合成2,3,5-三氯吡啶醇钠负载型催化剂研制, 主持, 研究所（学校）, 2014-01--2016-06
（ 2 ） 用于生产偏氟乙烯催化剂的制备及性能研究, 主持, 研究所（学校）, 2014-12--2016-12
（ 3 ） 木质素的接枝共聚反应研究, 主持, 国家级, 2012-01--2015-12
（ 4 ） 不对称羰基化, 主持, 市地级, 2013-01--2015-12

（1）系列新型手性亚磷酸酯配体合成及其在铜催化1,4-共轭加成反应中的应用研究   第七届全国配位化学会议   王来来   2013-07-28
（2）Synthesis of novel chiral bidentatephosphite ligands derived from pyranoside backbone of monosaccharides and their application in the Cu-Catalyzed conjugate addition of organozinc to enones   第四届手性中国2012   Qing-Lu Zhao, Lai-Lai Wang*   2012-09-17
（3）The effect of monophosphite ligand scaffold on the enantioselectivity of 1,4-conjugate addition of diethylzinc to cyclic enones   第四届手性中国2012   Wan Bo, Lai-Lai Wang *, Fuk Yee Kwong   2012-09-17
（4）新型手性亚磷酸酯配体的合成及其在不对称1,4-共轭加成反应中的应用   第十二届全国均相催化学术讨论会   王来来，赵庆鲁   2011-10-11
（5）新型手性亚磷酸酯配体的合成及其在不对称催化反应中的应用   第三届手性分子的合成，组装与应用学术研讨会   王来来   2011-07-22

已指导学生

贾小静  02  19133  

崔玉明  01  19133  

万博  02  19296  

赵庆鲁  01  20652  

邢爱萍  01  20652  

苗晓  02  20652  

现指导学生

逄增波  01  20652  

田密  02  63220  

郑治文  02  63220