070303-有机化学

生命有机化学, 不对称催化，天然产物合成

1998-09--2003-07   美国宾夕法尼亚州立大学   博士
1995-09--1998-07   中科院上海有机化学研究所   硕士
1991-09--1995-07   华东理工大学   学士

   

2011-08~现在, 中科院上海有机化学研究所, 研究员
2005-07~2011-07,美国伯林格英格翰药业公司, 高级、首席科学家
2003-09~2005-07,美国斯克里普斯研究所, 博士后

2020-01-01-今,Organic Chemistry Frontier, 编委
2019-01-01-今,Green Synthesis & Catalysis, 副主编
2018-01-01-今,Chinese Chemistry Letters, 编委
2015-10-01-今,RSC Advances, 副主编

高等有机化学

   

（1） 药明康德生命化学研究奖学者奖, , 其他, 2019
（2） 科技部万人计划, 部委级, 2019
（3） 科技部中青年科技创新领军人才, 部委级, 2018
（4） 国家杰出青年基金资助, 部委级, 2017
（5） 中国均相催化青年奖, 国家级, 2015
（6） Asian Core Program Lectureship Award, 其他, 2015
（7） 上海浦江人才计划, , 省级, 2013
（8） 上海市科技系统五四奖章, , 省级, 2013
（9） 青年****, , 国家级, 2012

[1] 汤文军, 董文锋. 聚合膦配体、包含其的过渡金属络合物、其制备和应用. CN: CN114805674B, 2023-08-11.

[2] 汤文军, 刘国都, 俞韩晓. 一种甘氨酸-亚磷酸二甲酯法合成草甘膦优化工艺及其膦谱原位核磁监测方法. CN: CN115181127A, 2022-10-14.

[3] 汤文军, 董文锋. 聚合膦配体、包含其的过渡金属络合物、其制备和应用. CN: CN114805674A, 2022-07-29.

[4] 汤文军, 杨贺. 羟考酮类化合物、其中间体及制备方法. CN: CN114573508A, 2022-06-03.

[5] 汤文军, 李博文. 双齿膦-膦氧配体及其中间体、制备方法和应用. CN: CN111848680B, 2021-12-14.

[6] 汤文军, 杨贺. 一种棉酚、其衍生物的制备方法及其中间体. CN: CN111848374A, 2020-10-30.

[7] 汤文军, 杨贺. 膦配体及其制备方法和催化合成邻位四取代联芳烃的应用. CN: CN111662331A, 2020-09-15.

[8] 汤文军, 徐广庆, 周明康. 一种联硼酸二醇酯、其制备方法、其中间体及其应用. CN: CN111440205A, 2020-07-24.

[9] 汤文军, 徐斯尧. 羟考酮类化合物及其中间体和制备方法. CN: CN111205296A, 2020-05-29.

[10] 汤文军, 司腾达, 李博文. 苯并氮杂磷杂茂膦氧配体及含其络合物、制备方法和应用. CN: CN109096338B, 2020-05-12.

[11] 汤文军, 徐斯尧. 一种金属配合物、中间体、其制备方法及应用. CN: CN110563771A, 2019-12-13.

[12] 汤文军, 钱超. 一种手性杂环化合物的制备方法. CN: CN110452183A, 2019-11-15.

[13] 汤文军, 朱金斌. 一种三级胺类化合物和双膦配体、其中间体及制备方法. CN: CN110437230A, 2019-11-12.

[14] 汤文军, 付文振, 刘国都. 手性双膦配体、其制备方法、中间体及应用. CN: CN109293700A, 2019-02-01.

[15] 汤文军, 江文豪. 一种联芳基双膦配体、其制备方法及应用. CN: CN107827929A, 2018-03-23.

[16] 汤文军, 李承喜, 万枫. 金属络合物、制备方法和应用及其中间体. CN: CN107445999A, 2017-12-08.

[17] 汤文军, 赵国庆, 胡乃夫. 过渡金属络合物、手性α-氨基三级硼酸酯及其制备方法. CN: CN106146543A, 2016-11-23.

[18] 汤文军, 黄林伟, 朱金斌. 芳基醇类化合物及艾司西酞普兰合成方法. CN: CN105732249A, 2016-07-06.

[19] 汤文军, 刘国都. 手性膦配体以及包含该配体的金属催化剂和它们的应用. CN: CN104650145A, 2015-05-27.

[20] 汤文军, 付文振. 一种取代的2,3-二氢苯并d1,3氧杂磷杂茂配体的制备方法. CN: CN104558038A, 2015-04-29.

[21] 汤文军, 李承喜. 手性膦配体以及包含该配体的金属催化剂和它们的应用. CN: CN103087105A, 2013-05-08.

   

[1] Yang, He, Yu, Hanxiao, Stolarzewicz, Izabela A, Tang, Wenjun. Enantioselective Transformations in the Synthesis of Therapeutic Agents. CHEMICAL REVIEWSnull. 2023, 123(15): 9397-9446, http://dx.doi.org/10.1021/acs.chemrev.3c00010.
[2] Zhu, Jinbin, Li, Zhenyue, Li, Jiaqi, Tian, Duanshuai, Xu, Ronghua, Tan, Zhiyong, Chen, Zhengwang, Tang, Wenjun. Enantioselective rhodium-catalyzed addition of arylboronic acids to N-heteroaryl ketones: synthesis of alpha-hydroxy acids. CHEMICAL SCIENCE[J]. 2023, 14(6): 1606-1612, http://dx.doi.org/10.1039/d2sc05907j.
[3] Gao, Ben, Chang, Yuqi, Tang, Wenjun. Prediction of the enantiomeric excess value for asymmetric transfer hydrogenation based on machine learning. ORGANIC CHEMISTRY FRONTIERS[J]. 2023, 10(6): 1456-1462, http://dx.doi.org/10.1039/d2qo01680j.
[4] Sun, Jiawei, Chen, Yuan, Ragab, Sherif Shaban, Gu, Wei, Tang, Ziqiang, Tang, Yuexun, Tang, Wenjun. Total Syntheses of Polyhydroxylated Steroids by an Unsaturation-Functionalization Strategy. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2023, http://dx.doi.org/10.1002/anie.202303639.
[5] Huang, Zhangwei, Pan, Xianhua, Guo, Lei, Tang, Wenjun. A Concise Total Synthesis of Steroid Scaffolds via a Palladium-Catalyzed Dearomatization Cyclization. SYNLETT[J]. 2022, 33(17): 1770-1774, http://dx.doi.org/10.1055/s-0042-1751356.
[6] Li, Zhenya, Xu, Ronghua, Guo, Huichuang, Yang, He, Xu, Guangqing, Shi, Enxue, Xiao, Junhua, Tang, Wenjun. Enantioselective Rhodium-Catalyzed Hydrogenation of (Z)-N-Sulfonyl-alpha-dehydroamido Boronic Esters. ORGANIC LETTERS[J]. 2022, 24(2): 714-719, http://dx.doi.org/10.1021/acs.orglett.1c04157.
[7] Li, Bowen, Luo, Bangke, Yang, He, Tang, Wenjun. Heck Reaction of N-Heteroaryl Halides for the Concise Synthesis of Chiral alpha-Heteroaryl-substituted Heterocycles. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2022, 61(38): http://dx.doi.org/10.1002/anie.202209087.
[8] 王楠, 汤文军. 铑催化全碳芳环的不对称氢化. 有机化学[J]. 2022, 42(10): 3419-3420, http://lib.cqvip.com/Qikan/Article/Detail?id=7108543148.
[9] Yang, He, Tang, Wenjun. Enantioselective construction of ortho-sulfur- or nitrogen-substituted axially chiral biaryls and asymmetric synthesis of isoplagiochin D. NATURE COMMUNICATIONS[J]. 2022, 13(1): http://dx.doi.org/10.1038/s41467-022-32360-7.
[10] 田端帅, 汤文军. 钯催化烯烃的不对称马氏氢胺羰基化反应. 有机化学[J]. 2021, 41(2): 865-866, http://lib.cqvip.com/Qikan/Article/Detail?id=7104320096.
[11] Xu, Ronghua, Gao, Zhenhua, Yu, Yiteng, Tang, Yehua, Tian, Duanshuai, Chen, Tian, Chen, Yibing, Xu, Guangqing, Shi, Enxue, Tang, Wenjun. A facile and practical preparation of P-chiral phosphine oxides. CHEMICAL COMMUNICATIONS[J]. 2021, 57(27): 3335-3338, http://dx.doi.org/10.1039/d1cc00646k.
[12] Xu, Ronghua, Gao, Zhenhua, Yu, Yiteng, Tang, Yehua, Tian, Duanshuai, Chen, Tian, Chen, Yibing, Xu, Guangqing, Shi, Enxue, Tang, Wenjun. A facile and practical preparation of P-chiral phosphine oxides dagger. CHEMICAL COMMUNICATIONS[J]. 2021, 57(27): 3335-3338, http://dx.doi.org/10.1039/d1cc00646k.
[13] Wu, Ting, Zhou, Qinghai, Tang, Wenjun. Enantioselective alpha-Carbonylative Arylation for Facile Construction of Chiral Spirocyclic beta,beta '-Diketones. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2021, 60(18): 9978-9983, http://dx.doi.org/10.1002/anie.202101668.
[14] Wan, Feng, Tang, Wenjun. Phosphorus Ligands from the Zhang Lab: Design, Asymmetric Hydrogenation, and Industrial Applications. CHINESE JOURNAL OF CHEMISTRY[J]. 2021, 39(4): 954-968, https://www.webofscience.com/wos/woscc/full-record/WOS:000634319800021.
[15] Sun, Jiawei, Gu, Wei, Yang, He, Tang, Wenjun. Enantioselective total synthesis of parnafungin A1 and 10a-epi-hirtusneanine. CHEMICAL SCIENCE[J]. 2021, 12(30): 10313-10320, http://dx.doi.org/10.1039/d1sc02919c.
[16] Tian, Duanshuai, Tang, Wenjun. Palladium-Catalyzed Asymmetric Markovnikov Hydroaminocarbonylation of Alkenes. CHINESE JOURNAL OF ORGANIC CHEMISTRY. 2021, 41(2): 865-866, http://dx.doi.org/10.6023/cjoc202100013.
[17] Peng, Henian, Li, Tiejun, Tian, Duanshuai, Yang, He, Xu, Guangqing, Tang, Wenjun. Metal-free reduction of unsaturated carbonyls, quinones, and pyridinium salts with tetrahydroxydiboron/water. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2021, 19(19): 4327-4337, http://dx.doi.org/10.1039/d1ob00300c.
[18] Wu, Ting, Tang, Wenjun. Construction of Bridged Polycyclic Skeletons via Transition-Metal Catalyzed Carbon-Carbon Bond-Forming Reactions. CHEMISTRY-A EUROPEAN JOURNALnull. 2021, 27(12): 3944-3956, http://dx.doi.org/10.1002/chem.202003863.
[19] Sun, Jiawei, Yang, He, Tang, Wenjun. Recent advances in total syntheses of complex dimeric natural products. CHEMICAL SOCIETY REVIEWSnull. 2021, 50(4): 2320-2336, http://dx.doi.org/10.1039/d0cs00220h.
[20] Tian, Duanshuai, Xu, Ronghua, Zhu, Jinbin, Huang, Jianxun, Dong, Wei, Claverie, Jerome, Tang, Wenjun. Asymmetric Hydroesterification of Diarylmethyl Carbinols. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2021, 60(12): 6305-6309, http://dx.doi.org/10.1002/anie.202015450.
[21] Wan, Feng, Wang, Nan, Zhu, Yuxin, Tang, Chuyan, Claverie, Jerome, Tang, Wenjun. Enantioselective hydrogenation of cyclic tetrasubstituted-olefinic dehydroamino acid derivatives. CHEMICAL COMMUNICATIONS[J]. 2021, 57(45): 5546-5549, http://dx.doi.org/10.1039/d1cc01277k.
[22] Li, Bowen, Luo, Bangke, Blakemore, Caroline A, Smith, Aaron C, Widlicka, Daniel W, Berritt, Simon, Tang, Wenjun. Synthesis of alpha-Heteroaryl Propionic Esters by Palladium-Catalyzed alpha-Heteroarylation of Silyl Ketene Acetals. ORGANIC LETTERS[J]. 2021, 23(16): 6439-6443, http://dx.doi.org/10.1021/acs.orglett.1c02257.
[23] Hanxiao Yu, He Yang, Enxue Shi, Wenjun Tang. Development and Clinical Application of Phosphorus-Containing Drugs. MEDICINE IN DRUG DISCOVERY[J]. 2020, 8: 100063-, http://dx.doi.org/10.1016/j.medidd.2020.100063.
[24] Li, Bowen, Aliyu, Muinat, Gao, Zhenhua, Li, Tiejun, Dong, Wei, Li, Junchen, Shi, Enxue, Tang, Wenjun. General Synthesis of Chiral alpha,alpha-Diaryl Carboxamides by Enantioselective Palladium-Catalyzed Cross-Coupling. ORGANIC LETTERS[J]. 2020, 22(13): 4974-4978, http://dx.doi.org/10.1021/acs.orglett.0c01489.
[25] Liu, Ziyue, Li, Tiejun, Zhao, Jianhong, Tang, Wenjun. A substituted tricyclohexylphosphane with "conformational lock". TETRAHEDRON[J]. 2020, 76(23): http://dx.doi.org/10.1016/j.tet.2020.131216.
[26] Li, Chengxi, Ragab, Sherif Shaban, Liu, Guodu, Tang, Wenjun. Enantioselective formation of quaternary carbon stereocenters in natural product synthesis: a recent update. NATURAL PRODUCT REPORTSnull. 2020, 37(2): 276-292, https://www.webofscience.com/wos/woscc/full-record/WOS:000520977600005.
[27] Zhou, Mingkang, Li, Kaidi, Chen, Dongping, Xu, Ronghua, Xu, Guangqing, Tang, Wenjun. Enantioselective Reductive Coupling of Imines Templated by Chiral Diboron. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2020, 142(23): 10337-10342, https://www.webofscience.com/wos/woscc/full-record/WOS:000541685800019.
[28] Xu, Ronghua, Yang, He, Tang, Wenjun. Efficient Synthesis of Chiral Drugs Facilated by P-Chiral Phosphorus Ligands. CHINESE JOURNAL OF ORGANIC CHEMISTRY[J]. 2020, 40(6): 1409-1422, http://dx.doi.org/10.6023/cjoc202003015.
[29] Yang, He, Tang, Wenjun. Efficient Enantioselective Syntheses of Chiral Natural Products Facilitated by Ligand Design. CHEMICAL RECORD[J]. 2020, 20(1): 23-40, https://www.webofscience.com/wos/woscc/full-record/WOS:000508067700003.
[30] Qan, Chao, Tang, Wenjun. A Versatile Synthesis of Vinyl-Substituted Heterocycles via Regio-and Enantioselective Pd-Catalyzed Tandem Allylic Substitution. ORGANIC LETTERS[J]. 2020, 22(11): 4483-4488, https://www.webofscience.com/wos/woscc/full-record/WOS:000538848600083.
[31] Mu, Xingye, Yu, Hanxiao, Peng, Henian, Xiong, Wenrui, Wu, Ting, Tang, Wenjun. Construction of Various Bridged Polycyclic Skeletons by Palladium-Catalyzed Dearomatization. ANGEWANDTECHEMIEINTERNATIONALEDITION[J]. 2020, 59(21): 8143-8147, https://www.webofscience.com/wos/woscc/full-record/WOS:000536953100030.
[32] Kaidi Li, Ming Nie, Wenjun Tang. Synthesis of α-tertiary allylsilanes by palladium-catalyzed hydrosilylation of 1,1-disubstituted allenes. GREEN SYNTHESIS AND CATALYSIS[J]. 2020, 1(2): 171-174, http://dx.doi.org/10.1016/j.gresc.2020.08.003.
[33] 许容华, 杨贺, 汤文军. P-手性膦配体促进的手性药物高效合成. 有机化学[J]. 2020, 40(6): 1409-1422, http://lib.cqvip.com/Qikan/Article/Detail?id=7102363750.
[34] Aliyu, Muinat A, Li, Bowen, Yang, He, Tang, Wenjun. Palladium-catalyzed reductive cross-coupling between alpha-bromo carboxamides and terminal alkynes. ORGANIC CHEMISTRY FRONTIERS[J]. 2020, 7(21): 3505-3508, https://www.webofscience.com/wos/woscc/full-record/WOS:000582936400021.
[35] Wu, Ting, Kang, Xuehua, Bai, Heng, Xiong, Wenrui, Xu, Guangqing, Tang, Wenjun. Enantioselective Construction of Spiro Quaternary Carbon Stereocenters via Pd-Catalyzed Intramolecular alpha-Arylation. ORGANIC LETTERS[J]. 2020, 22(12): 4602-4607, https://www.webofscience.com/wos/woscc/full-record/WOS:000543669800005.
[36] Yang, He, Sun, Jiawei, Gu, Wei, Tang, Wenjun. Enantioselective Cross-Coupling for Axially Chiral Tetra-ortho-Substituted Biaryls and Asymmetric Synthesis of Gossypol. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2020, 142(17): 8036-8043, http://dx.doi.org/10.1021/jacs.0c02686.
[37] 钱超, 汤文军. 镍氢催化的迁移脱氟烯烃偶联：由三氟甲基取代的烯烃构建偕二氟烯烃. 有机化学[J]. 2020, 40(4): 1076-1077, https://kns.cnki.net/KCMS/detail/detail.aspx?dbcode=CJFQ&dbname=CJFDLAST2020&filename=YJHU202004029&v=MDQxMzdMM0tQQ2ZEZTdHNEhOSE1xNDlIYllSOGVYMUx1eFlTN0RoMVQzcVRyV00xRnJDVVI3cWVadWR1Rnl2blY=.
[38] Qian, Chao, Tang, Wenjun. NiH-Catalyzed Migratory Defluorinative Olefin Cross-Coupling: Trifluoromethyl-Substituted Alkenes as Acceptor Olefins to Form gem-Difluoroalkenes. CHINESE JOURNAL OF ORGANIC CHEMISTRY[J]. 2020, 40(4): 1076-1077, http://dx.doi.org/10.6023/cjoc202000017.
[39] Wu, Zhenghan, Si, Tengda, Xu, Guangqing, Xu, Bin, Tang, Wenjun. Ligand-free nickel-catalyzed Kumada couplings of aryl bromides with tert-butyl Grignard reagents. CHINESE CHEMICAL LETTERS[J]. 2019, 30(3): 597-600, http://lib.cqvip.com/Qikan/Article/Detail?id=7001849598.
[40] 汤文军. Enantioselective Palladium-Catalyzed Cross-Coupling between α-Bromo Carboxamides an Arylboronic Acids. Angew. Chem. Int. Ed. 2019, 58, 11355-11359.. 2019, [41] Zhu, Jinbin, Huang, Linwei, Dong, Wei, Li, Naikai, Yu, Xingxin, Deng, WeiPing, Tang, Wenjun. Enantioselective Rhodium-Catalyzed Addition of Arylboroxines to N-Unprotected Ketimines: Efficient Synthesis of Cipargamin. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2019, 58(45): 16119-16123, https://www.webofscience.com/wos/woscc/full-record/WOS:000487455000001.
[42] Tang, Wenjun. Efficient synthesis of chiral drugs facilitated by ligand design. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETYnull. 2019, 258: https://www.webofscience.com/wos/woscc/full-record/WOS:000525061502512.
[43] 汤文军. P-Chiral Phosphorus Ligands on the Basis of a 2,3-Dihydrobenzo[d][1,3]oxaphosphole Motif for Asymmetric Catalysis. Acc. Chem. Res. 2019, 52, 1101-1112.. 2019, [44] Xu, Guangqing, Senanayake, Chris H, Tang, Wenjun. P-Chiral Phosphorus Ligands Based on a 2,3-Dihydrobenzod1,3oxaphosphole Motif for Asymmetric Catalysis. ACCOUNTS OF CHEMICAL RESEARCHnull. 2019, 52(4): 1101-1112, https://www.webofscience.com/wos/woscc/full-record/WOS:000465189800026.
[45] Li, Chengxi, Wan, Feng, Chen, Yuan, Peng, Henian, Tang, Wenjun, Yu, Shu, McWilliams, J Christopher, Mustakis, Jason, Samp, Lacey, Maguire, Robert J. Stereoelectronic Effects in Ligand Design: Enantioselective Rhodium-Catalyzed Hydrogenation of Aliphatic Cyclic Tetrasubstituted Enamides and Concise Synthesis of (R)-Tofacitinib. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2019, 58(38): 13573-13583, https://www.doi.org/10.1002/anie.201908089.
[46] Xiong, Wenrui, Xu, Guangqing, Yu, Xinhong, Tang, Wenjun. P-Chiral Monophosphorus Ligands for Asymmetric Copper-Catalyzed Allylic Alkylation. ORGANOMETALLICS[J]. 2019, 38(20): 4003-4013, [47] Li, Bowen, Li, Tiejun, Aliyu, Muinat A, Li, Zhen Hua, Tang, Wenjun. Enantioselective Palladium-Catalyzed Cross-Coupling of alpha-Bromo Carboxamides and Aryl Boronic Acids. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2019, 58(33): 11355-11359, [48] Zhenghan Wu, Tengda Si, Guangqing Xu, Bin Xu, Wenjun Tang. Ligand-free nickel-catalyzed Kumada couplings of aryl, bromides with tert-butyl Grignard reagents. 中国化学快报:英文版[J]. 2019, 30(3): 597-600, http://lib.cqvip.com/Qikan/Article/Detail?id=7001849598.
[49] Dong, Wenfeng, Xu, Guangqing, Tang, Wenjun. Enantioselective palladium-catalyzed C(sp(2))-H carbamoylation. TETRAHEDRON[J]. 2019, 75(24): 3239-3247, http://dx.doi.org/10.1016/j.tet.2019.03.038.
[50] Braje, Wilfried, Gallou, Fabrice, Handa, Sachin, Tang, Wenjun. Sustainable and Affordable Chemistry. CHEMCATCHEMnull. 2019, 11(23): 5660-5661, [51] Tian, Duanshuai, Peng, Henian, Liu, Ziyue, Tang, Wenjun. Optically active N-alkyl aziridines via stereospecific reductive cyclization of -mesylated acetamides. ORGANIC CHEMISTRY FRONTIERS[J]. 2018, 5(18): 2723-2727, https://www.webofscience.com/wos/woscc/full-record/WOS:000445221000013.
[52] Tian, Duanshuai, Li, Chengxi, Gu, Guoxian, Peng, Henian, Zhang, Xumu, Tang, Wenjun. Stereospecific Nucleophilic Substitution with Arylboronic Acids as Nucleophiles in the Presence of a CONH Group. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2018, 57(24): 7176-7180, https://www.webofscience.com/wos/woscc/full-record/WOS:000434350400036.
[53] Jiang, Wenhao, Zhao, Qing, Tang, Wenjun. Efficient P-Chiral Biaryl Bisphosphorus Ligands for Palladium-Catalyzed Asymmetric Hydrogenation. CHINESE JOURNAL OF CHEMISTRY[J]. 2018, 36(2): 153-156, http://lib.cqvip.com/Qikan/Article/Detail?id=674838554.
[54] Wenhao Jiang, Qing Zhao, Wenjun Tang. Efficient P-Chiral Biaryl Bisphosphorus Ligands for Palladium-Catalyzed Asymmetric Hydrogenation. 中国化学：英文版[J]. 2018, 36(2): 153-156, http://lib.cqvip.com/Qikan/Article/Detail?id=674838554.
[55] Liu, Guodu, Fu, Wenzhen, Mu, Xingye, Wu, Ting, Nie, Ming, Li, Kaidi, Xu, Xiaodong, Tang, Wenjun. Pyrrolidines and piperidines bearing chiral tertiary alcohols by nickel-catalyzed enantioselective reductive cyclization of N-alkynones. COMMUNICATIONS CHEMISTRY[J]. 2018, 1(1): https://doaj.org/article/8f3c1959c711401dad4038c81216f1af.
[56] Zhou, Qinghai, Tang, Wenjun, Chung, Lung Wa. Mechanistic insights into asymmetric reductive coupling of isoquinolines by a chiral diboron with DFT calculations. JOURNAL OF ORGANOMETALLIC CHEMISTRY[J]. 2018, 864: 97-104, http://dx.doi.org/10.1016/j.jorganchem.2018.02.001.
[57] Rao, Xiaofeng, Li, Naikai, Bai, Heng, Dai, Chaodi, Wang, Zheng, Tang, Wenjun. Efficient Synthesis of (-)-Corynoline by Enantioselective Palladium-Catalyzed alpha-Arylation with Sterically Hindered Substrates. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2018, 57(38): 12328-12332, https://www.webofscience.com/wos/woscc/full-record/WOS:000444225100017.
[58] Liu, Jiawang, Nie, Ming, Zhou, Qinghai, Gao, Shen, Jiang, Wenhao, Chung, Lung Wa, Tang, Wenjun, Ding, Kuiling. Enantioselective palladium-catalyzed diboration of 1,1-disubstituted allenes. CHEMICALSCIENCE[J]. 2017, 8(7): 5161-5165, http://dx.doi.org/10.1039/c7sc01254c.
[59] Zhao, Guoqing, Xu, Guangqing, Qian, Chao, Tang, Wenjun. Efficient Enantioselective Syntheses of (+)-Dalesconol A and B. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2017, 139(9): 3360-3363, https://www.webofscience.com/wos/woscc/full-record/WOS:000396185700014.
[60] Zhang, Zhongyin, Wang, Jinxin, Li, Jian, Yang, Fan, Liu, Guodu, Tang, Wenjun, He, Weiwei, Fu, JianJun, Shen, YunHeng, Li, Ang, Zhang, WeiDong. Total Synthesis and Stereochemical Assignment of Delavatine A: Rh-Catalyzed Asymmetric Hydrogenation of Indene-Type Tetrasubstituted Olefins and Kinetic Resolution through Pd Catalyzed Triflamide-Directed C-H Olefination. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2017, 139(15): 5558-5567, https://www.webofscience.com/wos/woscc/full-record/WOS:000399966000038.
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[96] Luo, Renshi, Li, Ke, Hu, Yuling, Tang, Wenjun. Enantioselective Rhodium-Catalyzed Addition of Arylboronic Acids to Trifluoromethyl Ketones. ADVANCED SYNTHESIS & CATALYSIS[J]. 2013, 355(7): 1297-1302, http://www.irgrid.ac.cn/handle/1471x/870677.
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[99] Li Ke, Hu Naifu, Luo Renshi, Yuan Weicheng, Tang Wenjun. A Chiral Ruthenium-Monophosphine Catalyst for Asymmetric Addition of Arylboronic Acids to Aryl Aldehydes. J. ORG. CHEM.[J]. 2013, 78(12): 6350-6355, http://www.irgrid.ac.cn/handle/1471x/870664.
[100] 汤文军. Design of Phosphorus Ligands with Deep Chiral Pockets: Practical Synthesis fo Chiral β-Arylamines by Asymmetric Hydrogenation. Angew. Chem., Int. Ed. 2013, 52, 4235-4238. 2013, [101] Liu, Guodu, Liu, Xiangqian, Cai, Zhihua, Jiao, Guangjun, Xu, Guangqing, Tang, Wenjun. Design of Phosphorus Ligands with Deep Chiral Pockets: Practical Synthesis of Chiral beta-Arylamines by Asymmetric Hydrogenation. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2013, 52(15): 4235-4238, http://dx.doi.org/10.1002/anie.201300646.
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（1） Air-stable P-chiral Phosphorus Ligands for Asymmetric Catalysis and Synthesis, The Strem Chemiker, 2019-10, 第 1 作者

   

（ 1 ） 富电子、刚性P手性配体在不对称催化反应中的前沿和基础研究, 参与, 国家级, 2015-01--2019-12
（ 2 ） 新型膦配体的发展和在过渡金属催化反应中的应用, 主持, 国家级, 2013-01--2016-12
（ 3 ） 导向绿色合成的高效、新型、实用的催化剂研究 , 主持, 省级, 2013-07--2016-06
（ 4 ） 不对称环化反应方法学以及在天然产物和药物合成中的应用, 主持, 国家级, 2016-01--2019-12
（ 5 ） 催化不对称合成, 主持, 国家级, 2017-11--2022-12
（ 6 ） 联硼介导的[3,3]-σ重排: 不对称还原偶联反应研究, 主持, 国家级, 2020-11--2024-12
（ 7 ） 新型手性联二氢/四氢异喹啉骨架膦配体的设计、合成及其应用研究, 主持, 国家级, 2018-01--2021-12
（ 8 ） 科技部“万人计划”科技创新领军人才, 主持, 国家级, 2019-02--2022-01
（ 9 ） 三联芳膦钯碳氮偶联催化剂的研发及产业化, 参与, 省级, 2020-02--2024-12
（ 10 ） 生物活性有机分子的精准合成和作用机制研究, 参与, 部委级, 2016-07--2021-06
（ 11 ） 催化不对称大位阻偶联反应, 主持, 市地级, 2021-01--2023-12
（ 12 ） 配体促进的高效偶联反应研究, 参与, 部委级, 2016-07--2020-12

已指导学生

赵庆  硕士研究生  070303-有机化学  

郭盼  硕士研究生  085216-化学工程  

徐广庆  博士研究生  070303-有机化学  

杜康  博士研究生  070303-有机化学  

胡乃夫  博士研究生  070303-有机化学  

陈栋萍  硕士研究生  070303-有机化学  

杨心童  硕士研究生  070303-有机化学  

李承喜  博士研究生  070303-有机化学  

付文振  博士研究生  070303-有机化学  

李博文  博士研究生  070303-有机化学  

聂明  博士研究生  070303-有机化学  

柏珩  硕士研究生  085216-化学工程  

陈远  博士研究生  070303-有机化学  

穆星烨  博士研究生  070303-有机化学  

李凯迪  硕士研究生  070303-有机化学  

田端帅  博士研究生  070303-有机化学  

钱超  博士研究生  070303-有机化学  

现指导学生

吴婷  博士研究生  070303-有机化学  

周明康  博士研究生  070303-有机化学  

顾威  硕士研究生  085216-化学工程  

柏珩  博士研究生  070303-有机化学  

万枫  博士研究生  070303-有机化学  

唐自强  硕士研究生  070303-有机化学  

林尧东  硕士研究生  070303-有机化学  

赵帝  硕士研究生  085216-化学工程  

董文锋  博士研究生  070303-有机化学  

黄建勋  硕士研究生  070303-有机化学  

朱雨欣  硕士研究生  070303-有机化学  

常钦仁  硕士研究生  086000-生物与医药  

付鑫鹏  硕士研究生  086000-生物与医药  

高犇  硕士研究生  085600-材料与化工  

贺东阳  硕士研究生  086000-生物与医药  

温韬  博士研究生  070303-有机化学  

田威  博士研究生  070303-有机化学  

唐叶华  硕士研究生  070303-有机化学