基本信息
魏炜  男  博导  中国科学院过程工程研究所
电子邮件: weiwei@ipe.ac.cn
通信地址: 北京市海淀区中关村北二条一号
邮政编码: 100190

教育背景

2004-09--2011-06   中国科学院过程工程研究所   博士
2000-09--2004-06   北京大学医学部   学士

工作经历

   
工作简历
2018-09~现在, 中国科学院过程工程研究所, 研究员
2016-10~2018-09,中国科学院过程工程研究所, 项目研究员
2011-07~2016-10,中国科学院过程工程研究所, 副研究员
社会兼职
2019-12-01-今,中国生物物理学会智能诊疗技术和材料生物学专委会委员, 委员
2019-10-01-今,中国医药生物技术造影技术分会专委会委员, 专委会委员
2019-04-01-今,北京抗癌协会青年理事会理事, 青年理事会理事
2019-02-01-今,中国抗癌协会青年理事会理事, 青年理事会理事
2018-08-01-今,中国颗粒学会生物颗粒专业委员会委员, 专业委员会委员
2018-08-01-今,中国颗粒学会第三届青年理事会理事, 青年理事会理事
2017-10-01-今,中国医药生物技术协会生物技术分会委员会委员, 委员
2016-12-01-今,中国化工协会专业技术委员会青年专业委员会副秘书长, 副秘书长
2014-01-01-今,中国颗粒学会生物颗粒专业委员会, 委员
2012-01-01-今,中国科学院青年创新促进会, 会员

教授课程

前沿化学实验
生物过程工程

出版信息

   
发表论文
[1] Yanlin Lv, Wei Wei, Guanghui Ma. Recent advances in platelet engineering for anti-cancer therapies. Particuology[J]. 2022, 64: 2-13, [2] 马光辉. Ferritin-based targeted delivery of arsenic to diverse leukemia types confers strong anti-leukemia therapeutic effects. NATURE NANOTECHNOLOGY. 2021, [3] Wang, Changlong, Zhang, Wei, He, Yanjie, Gao, Zirui, Liu, Liyuan, Yu, Siyao, Hu, Yuxing, Wang, Shuang, Zhao, Chaochao, Li, Hui, Shi, Jinan, Zhou, Wu, Li, Feng, Yue, Hua, Li, Yuhua, Wei, Wei, Ma, Guanghui, Ma, Ding. Ferritin-based targeted delivery of arsenic to diverse leukaemia types confers strong anti-leukaemia therapeutic effects. NATURE NANOTECHNOLOGY. 2021, [4] Zhang, Xiao, Ding, Zhaowen, Ma, Guanghui, Wei, Wei. A High-Resolution Ternary Model Demonstrates How PEGylated 2D Nanomaterial Stimulates Integrin alpha(v)beta(8) on Cell Membrane. ADVANCED SCIENCE[J]. 2021, 8(11): http://dx.doi.org/10.1002/advs.202004506.
[5] Gong, Changguo, Zhang, Xiao, Shi, Min, Li, Feng, Wang, Shuang, Wang, Yan, Wang, Yugang, Wei, Wei, Ma, Guanghui. Tumor Exosomes Reprogrammed by Low pH Are Efficient Targeting Vehicles for Smart Drug Delivery and Personalized Therapy against their Homologous Tumor. ADVANCED SCIENCE[J]. 2021, 8(10): https://doaj.org/article/966078ac3703478a960b38234958fe99.
[6] 马光辉. Macrophage-tumor chimeric exosomes accumulate in both lymph node and tumor for activation of immune response and tumor microenvironment. SCIENCE TRANSLATIONAL MEDICINE. 2021, [7] Hu, Yuning, Gong, Fangling, Yan, Xingran, Li, Tong, Chen, Jingkun, Wei, Wei, Ma, Guanghui. Effects of membrane pore activation on microporous membrane emulsification process and emulsion droplet formation. COLLOID AND POLYMER SCIENCE. 2021, [8] Tian, Ying, Zhang, Fan, Qiu, Yefeng, Wang, Shuang, Li, Feng, Zhao, Jiawei, Pan, Chao, Tao, Yong, Yu, Di, Wei, Wei. Reduction of choroidal neovascularization via cleavable VEGF antibodies conjugated to exosomes derived from regulatory T cells. NATURE BIOMEDICAL ENGINEERING[J]. 2021, 5(9): 968-+, http://dx.doi.org/10.1038/s41551-021-00764-3.
[9] Xie, Xiaoling, Hu, Yuxing, Ye, Tong, Chen, Yiran, Zhou, Lijuan, Li, Feng, Xi, Xiaobo, Wang, Shuang, He, Yanjie, Gao, Xiaoyong, Wei, Wei, Ma, Guanghui, Li, Yuhua. Therapeutic vaccination against leukaemia via the sustained release of co-encapsulated anti-PD-1 and a leukaemia-associated antigen. NATURE BIOMEDICAL ENGINEERING[J]. 2021, 5(5): 414-+, http://dx.doi.org/10.1038/s41551-020-00624-6.
[10] Song, Cui, Zhang, Xiao, Wei, Wei, Ma, Guanghui. Principles of regulating particle multiscale structures for controlling particle-cell interaction process. CHEMICAL ENGINEERING SCIENCE[J]. 2021, 232: https://www.webofscience.com/wos/woscc/full-record/WOS:000608126300009.
[11] Zhao, Jiawei, Wang, Yugang, Wang, Wenjing, Tian, Ying, Gan, Zhongdong, Wang, Yanlei, He, Hongyan, Chen, Wei, Zhang, Xiao, Wu, Yuanbin, Jia, Rongrong, Shi, Min, Wei, Wei, Ma, Guanghui. In situ growth of nano-antioxidants on cellular vesicles for efficient reactive oxygen species elimination in acute inflammatory diseases. NANO TODAY[J]. 2021, 40: http://dx.doi.org/10.1016/j.nantod.2021.101282.
[12] Zhang, Xiao, Ma, Guanghui, Wei, Wei. Simulation of nanoparticles interacting with a cell membrane: probing the structural basis and potential biomedical application. NPG ASIA MATERIALS[J]. 2021, 13(1): http://dx.doi.org/10.1038/s41427-021-00320-0.
[13] Bao, Weier, Tian, Falin, Lyu, Chengliang, Liu, Bin, Li, Bin, Zhang, Luyao, Liu, Xianwu, Li, Feng, Li, Dan, Gao, Xiaoyong, Wang, Shuo, Wei, Wei, Shi, Xinghua, Li, Yuan. Experimental and theoretical explorations of nanocarriers' multistep delivery performance for rational design and anticancer prediction. SCIENCE ADVANCES[J]. 2021, 7(6): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864577/.
[14] Bao, Weier, Liu, Ming, Meng, Jiaqi, Liu, Siyuan, Wang, Shuang, Jia, Rongrong, Wang, Yugang, Ma, Guanghui, Wei, Wei, Tian, Zhiyuan. MOFs-based nanoagent enables dual mitochondrial damage in synergistic antitumor therapy via oxidative stress and calcium overload. NATURE COMMUNICATIONS[J]. 2021, 12(1): http://dx.doi.org/10.1038/s41467-021-26655-4.
[15] Lv, Yanlin, Li, Feng, Wang, Shuang, Lu, Guihong, Bao, Weier, Wang, Yugang, Tian, Zhiyuan, Wei, Wei, Ma, Guanghui. Near-infrared light-triggered platelet arsenal for combined photothermal-immunotherapy against cancer. SCIENCE ADVANCES[J]. 2021, 7(13): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997510/.
[16] Xu, Bolong, Cui, Yan, Wang, Weiwei, Li, Shanshan, Lyu, Chengliang, Wang, Shuang, Bao, Weier, Wang, Hongyu, Qin, Meng, Liu, Zhen, Wei, Wei, Liu, Huiyu. Immunomodulation-Enhanced Nanozyme-Based Tumor Catalytic Therapy. ADVANCED MATERIALS[J]. 2020, 32(33): https://www.webofscience.com/wos/woscc/full-record/WOS:000545735200001.
[17] Wu, Guanghao, Wei, Wei, Zhang, Jinfeng, Nie, Weidong, Yuan, Lan, Huang, Yuanyu, Zuo, Liping, Huang, Lili, Xi, Xiaobo, Xie, HaiYan. A self-driven bioinspired nanovehicle by leukocyte membrane-hitchhiking for early detection and treatment of atherosclerosis. BIOMATERIALS[J]. 2020, 250: http://dx.doi.org/10.1016/j.biomaterials.2020.119963.
[18] Lyu, Chengliang, Lu, Guihong, Bao, Weier, Li, Feng, Wang, Shuang, Zhang, Fan, Gao, Xiaoyong, Kamiya, Hidehiro, Ma, Guanghui, Wei, Wei. Engineering magnetosomes with chimeric membrane and hyaluronidase for efficient delivery of HIF-1 siRNA into deep hypoxic tumors. CHEMICAL ENGINEERING JOURNAL[J]. 2020, 398: http://dx.doi.org/10.1016/j.cej.2020.125453.
[19] 吕程亮, 张帆, 魏炜, 谢海燕. 基于肿瘤微环境构建纳米药物的研究进展. 生物加工过程. 2020, 18(6): 799-805, http://lib.cqvip.com/Qikan/Article/Detail?id=7103568530.
[20] Qing, Shuang, Lyu, Chengliang, Zhu, Li, Pan, Chao, Wang, Shuang, Li, Feng, Wang, Jianghua, Yue, Hua, Gao, Xiaoyong, Jia, Rongrong, Wei, Wei, Ma, Guanghui. Biomineralized Bacterial Outer Membrane Vesicles Potentiate Safe and Efficient Tumor Microenvironment Reprogramming for Anticancer Therapy. ADVANCED MATERIALS[J]. 2020, 32(47): https://www.webofscience.com/wos/woscc/full-record/WOS:000574885100001.
[21] Wang, Jianghua, Wang, Shuang, Ye, Tong, Li, Feng, Gao, Xiaoyong, Wang, Yan, Ye, Peng, Qing, Shuang, Wang, Changlong, Yue, Hua, Wu, Jie, Wei, Wei, Ma, Guanghui. Choice of Nanovaccine Delivery Mode Has Profound Impacts on the Intralymph Node Spatiotemporal Distribution and Immunotherapy Efficacy. ADVANCED SCIENCE[J]. 2020, 7(19): https://doaj.org/article/eb7b525e7575405c8b46079997716871.
[22] Ding, Zhaowen, Luo, Nana, Yue, Hua, Gao, Yongjun, Ma, Guanghui, Wei, Wei. In vivo immunological response of exposure to PEGylated graphene oxide via intraperitoneal injection. JOURNAL OF MATERIALS CHEMISTRY B[J]. 2020, 8(31): 6845-6856, https://www.webofscience.com/wos/woscc/full-record/WOS:000558894300020.
[23] Lu, Guihong, Zuo, Liping, Zhang, Jinfeng, Zhu, Houshun, Zhuang, Wanru, Wei, Wei, Xie, HaiYan. Two-step tumor-targeting therapy via integrating metabolic lipid-engineering with in situ click chemistry. BIOMATERIALS SCIENCE[J]. 2020, 8(8): 2283-2288, https://www.webofscience.com/wos/woscc/full-record/WOS:000530471400017.
[24] Pan, Chao, Wu, Jun, Qing, Shuang, Zhang, Xiao, Zhang, Lulu, Yue, Hua, Zeng, Ming, Wang, Bin, Yuan, Zheng, Qiu, Yefeng, Ye, Huahu, Wang, Dongshu, Liu, Xiankai, Sun, Peng, Liu, Bo, Feng, Erling, Gao, Xiaoyong, Zhu, Li, Wei, Wei, Ma, Guanghui, Wang, Hengliang. Biosynthesis of Self-Assembled Proteinaceous Nanoparticles for Vaccination. ADVANCED MATERIALS[J]. 2020, 32(42): https://www.webofscience.com/wos/woscc/full-record/WOS:000565425700001.
[25] Xi, Xiaobo, Ye, Tong, Wang, Shuang, Na, Xiangming, Wang, Jianghua, Qing, Shuang, Gao, Xiaoyong, Wang, Changlong, Li, Feng, Wei, Wei, Ma, Guanghui. Self-healing microcapsules synergetically modulate immunization microenvironments for potent cancer vaccination. SCIENCE ADVANCES[J]. 2020, 6(21): https://www.webofscience.com/wos/woscc/full-record/WOS:000537235300007.
[26] Feng Li, Weidong Nie, Fan Zhang, Guihong Lu, Chengliang Lv, Yanlin Lv, Weier Bao, Lijun Zhang, Shuang Wang, Xiaoyong Gao, Wei Wei, HaiYan Xie. Engineering Magnetosomes for High-Performance Cancer Vaccination. ACS CENTRAL SCIENCE[J]. 2019, 5(5): 796-807, http://ir.ipe.ac.cn/handle/122111/28189.
[27] Tong, Liping, Liao, Qing, Zhao, Yuetao, Huang, Hao, Gao, Ang, Zhang, Wei, Gao, Xiaoyong, Wei, Wei, Guan, Min, Chu, Paul K, Wang, Huaiyu. Near-infrared light control of bone regeneration with biodegradable photothermal osteoimplant. BIOMATERIALS[J]. 2019, 193: 1-11, http://ir.ipe.ac.cn/handle/122111/27870.
[28] Liu, Ming, Meng, Jiaqi, Bao, Weier, Liu, Siyuan, Wei, Wei, Ma, Guanghui, Tian, Zhiyuan. Single-Chromophore-Based Therapeutic Agent Enables Green-Light-Triggered Chemotherapy and Simultaneous Photodynamic Therapy to Cancer Cells. ACS APPLIED BIO MATERIALS[J]. 2019, 2(7): 3068-3076, [29] Bao, Weier, Liu, Xianwu, Lv, Yanlin, Lu, GuiHong, Li, Feng, Zhang, Fan, Liu, Bin, Li, Dan, Wei, Wei, Li, Yuan. Nanolongan with Multiple On-Demand Conversions for Ferroptosis-Apoptosis Combined Anticancer Therapy. ACS NANO[J]. 2019, 13(1): 260-273, http://ir.ipe.ac.cn/handle/122111/27815.
[30] Xiaoling Wu, Hua Yue, Yuanyu Zhang, Xiaoyong Gao, Xiaoyang Li, Licheng Wang, Yufei Cao, Miao Hou, Haixia An, Lin Zhang, Sai Li, Jingyuan Ma, He Lin, Yanan Fu, Hongkai Gu, Wenyong Lou, Wei Wei, Richard N Zare, Jun Ge. Packaging and delivering enzymes by amorphous metal-organic frameworks. Nature Communications[J]. 2019, 10(1): 1-8, http://dx.doi.org/10.1038/s41467-019-13153-x.
[31] Zhao, Chaochao, Feng, Hongqing, Zhang, Lijun, Li, Zhe, Zou, Yang, Tan, Puchuan, Ouyang, Han, Jiang, Dongjie, Yu, Min, Wang, Chan, Li, Hu, Xu, Lingling, Wei, Wei, Li, Zhou. Highly Efficient In Vivo Cancer Therapy by an Implantable Magnet Triboelectric Nanogenerator. ADVANCED FUNCTIONAL MATERIALS[J]. 2019, 29(41): [32] Zhang, Fan, Li, Feng, Lu, GuiHong, Nie, Weidong, Zhang, Lijun, Lv, Yanlin, Bao, Weier, Gao, Xiaoyong, Wei, Wei, Pu, Kanyi, Xie, HaiYan. Engineering Magnetosomes for Ferroptosis/Immunomodulation Synergism in Cancer. ACS NANO[J]. 2019, 13(5): 5662-5673, [33] Gu, Zonglin, Chen, Serena H, Ding, Zhaowen, Song, Wei, Wei, Wei, Liu, Shengtang, Ma, Guanghui, Zhou, Ruhong. The molecular mechanism of robust macrophage immune responses induced by PEGylated molybdenum disulfide. NANOSCALE[J]. 2019, 11(46): 22293-22304, http://dx.doi.org/10.1039/c9nr04358f.
[34] 宋翠, 张潇, 魏炜, 马光辉. 原子力显微镜在测定颗粒与细胞相互作用中的应用. 生物加工过程. 2019, 17(1): 53-59, http://lib.cqvip.com/Qikan/Article/Detail?id=7001192184.
[35] Lu, Guihong, Lv, Chengliang, Bao, Weier, Li, Feng, Zhang, Fan, Zhang, Lijun, Wang, Shuang, Gao, Xiaoyong, Zhao, Dongxu, Wei, Wei, Xie, Haiyan. Antimonene with two-orders-of-magnitude improved stability for high-performance cancer theranostics. CHEMICAL SCIENCE[J]. 2019, 10(18): 4847-4853, http://ir.ipe.ac.cn/handle/122111/28203.
[36] Wang, Shuang, Wang, Jianghua, Wei, Wei, Ma, Guanghui. Exosomes: The Indispensable Messenger in Tumor Pathogenesis and the Rising Star in Antitumor Applications. ADVANCED BIOSYSTEMS[J]. 2019, 3(5): http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000471816000006.
[37] Chen, Pengyu, Yue, Hua, Zhai, Xiaobo, Huang, Zihan, Ma, GuangHui, Wei, Wei, Yan, LiTang. Transport of a graphene nanosheet sandwiched inside cell membranes. SCIENCE ADVANCES[J]. 2019, 5(6): https://www.webofscience.com/wos/woscc/full-record/WOS:000473798500072.
[38] Zhang, Lijun, Zhang, Xiao, Lu, Guihong, Li, Feng, Bao, Weier, Song, Cui, Wei, Wei, Ma, Guanghui. Cell Membrane Camouflaged Hydrophobic Drug Nanoflake Sandwiched with Photosensitizer for Orchestration of Chemo-Photothermal Combination Therapy. SMALL[J]. 2019, 15(20): [39] Nie, Weidong, Wei, Wei, Zuo, Liping, Lv, Chengliang, Zhang, Fan, Lu, GuiHong, Li, Feng, Wu, Guanghao, Huang, LiLi, Xi, Xiaobo, Xie, HaiYan. Magnetic Nanoclusters Armed with Responsive PD-1 Antibody Synergistically Improved Adoptive T-Cell Therapy for Solid Tumors. ACS NANO[J]. 2019, 13(2): 1469-1478, http://ir.ipe.ac.cn/handle/122111/28347.
[40] Xi, Xiaobo, Zhang, Lijun, Lu, Guihong, Gao, Xiaoyong, Wei, Wei, Ma, Guanghui. Lymph Node-Targeting Nanovaccine through Antigen-CpG Self-Assembly Potentiates Cytotoxic T Cell Activation. JOURNAL OF IMMUNOLOGY RESEARCH[J]. 2018, 2018: http://ir.ipe.ac.cn/handle/122111/26820.
[41] Lu, Guihong, Li, Feng, Zhang, Fan, Huang, LiLi, Zhang, Lijun, Lv, Yanlin, Wei, Wei, Xie, HaiYan. Amplifying Nanoparticle Targeting Performance to Tumor via Diels-Alder Cycloaddition. ADVANCED FUNCTIONAL MATERIALS[J]. 2018, 28(30): http://ir.ipe.ac.cn/handle/122111/26686.
[42] Zhang, Xiao, Song, Cui, Ma, Guanghui, Wei, Wei. Mechanical determination of particle-cell interactions and the associated biomedical applications. JOURNAL OF MATERIALS CHEMISTRY B[J]. 2018, 6(44): 7129-7143, http://ir.ipe.ac.cn/handle/122111/26762.
[43] Wang, Shuang, Ni, Dezhi, Yue, Hua, Luo, Nana, Xi, Xiaobo, Wang, Yugang, Shi, Min, Wei, Wei, Ma, Guanghui. Exploration of Antigen Induced CaCO3 Nanoparticles for Therapeutic Vaccine. SMALL[J]. 2018, 14(14): http://www.irgrid.ac.cn/handle/1471x/1764245.
[44] Libing Mu, Zhongyuan Tu, Lin Miao, Hefei Ruan, Ning Kang, Yongzhen Hei, Jiahuan Chen, Wei Wei, Fangling Gong, Bingjie Wang, Yanan Du, Guanghui Ma, Matthias W Amerein, Tie Xia, Yan Shi. A phosphatidylinositol 4,5-bisphosphate redistribution-based sensing mechanism initiates a phagocytosis programing. NATURE COMMUNICATIONS[J]. 2018, 9(1): http://ir.ipe.ac.cn/handle/122111/26150.
[45] Zhang, Fan, Zhao, Longjian, Wang, Shumin, Yang, Jun, Lu, Guihong, Luo, Nana, Gao, Xiaoyong, Ma, Guanghui, Xie, HaiYan, Wei, Wei. Construction of a Biomimetic Magnetosome and Its Application as a SiRNA Carrier for High-Performance Anticancer Therapy. ADVANCED FUNCTIONAL MATERIALS[J]. 2018, 28(1): http://www.irgrid.ac.cn/handle/1471x/1763945.
[46] Li, Zhiheng, Wang, Qian, Wang, Yingqian, Ma, Qinqin, Wang, Jie, Li, Zhihao, Li, Yingxue, Lv, Xiaobo, Wei, Wei, Chen, Lang, Yuan, Quan. Background-free latent fingerprint imaging based on nanocrystals with long-lived luminescence and pH-guided recognition. NANO RESEARCH[J]. 2018, 11(12): 6167-6176, http://lib.cqvip.com/Qikan/Article/Detail?id=6100057005.
[47] Wei Wei. Cancer cell membrane-biomimetic nanoprobes capable of two-photon excitation and near-infrared emission for high-performance fluorescence imaging of intravital tumor. ACS NANO. 2018, [48] Wei Wei. Amplifying nanoparticle targeting performance to tumor via Diel-Alder cycloaddition. ADVANCED FUNCTIONAL MATERIALS. 2018, [49] Liu, Haoyang, Hu, Xiaoxia, Wang, Jie, Liu, Meng, Wei, Wei, Yuan, Quan. Direct low-temperature synthesis of ultralong persistent luminescence nanobelts based on a biphasic solution-chemical reaction. CHINESE CHEMICAL LETTERS[J]. 2018, 29(11): 1641-1644, http://lib.cqvip.com/Qikan/Article/Detail?id=676661167.
[50] Haoyang Liu, Xiaoxia Hu, Jie Wang, Meng Liu, Wei Wei, Quan Yuan. Direct low-temperature synthesis of ultralong persistent luminescence nanobelts based on a biphasic solution-chemical reaction. 中国化学快报:英文版. 2018, 29(11): 1641-1644, http://lib.cqvip.com/Qikan/Article/Detail?id=676661167.
[51] Lv, Yanlin, Liu, Ming, Zhang, Yong, Wang, Xuefei, Zhang, Fan, Li, Feng, Bao, WeiEr, Wang, Jie, Zhang, Yuanlin, Wei, Wei, Ma, Guanghui, Zhao, Liancheng, Tian, Zhiyuan. Cancer Cell Membrane-Biomimetic Nanoprobes with Two-Photon Excitation and Near-Infrared Emission for Intravital Tumor Fluorescence Imaging. ACS NANO[J]. 2018, 12(2): 1350-1358, http://www.irgrid.ac.cn/handle/1471x/1764179.
[52] Zhao, Lan, Wei, Wei, Huang, Yongdong, Zhang, Rongyue, Zhu, Kai, Hao, Dongxia, Su, Zhiguo, Ma, Guanghui. A novel rProtein A chromatographic media for enhancing cleaning-in-place performance. JOURNAL OF IMMUNOLOGICAL METHODS[J]. 2018, 460: 45-50, http://dx.doi.org/10.1016/j.jim.2018.06.008.
[53] Yue, Hua, Yuan, Lan, Zhang, Weiwei, Zhang, Shujia, Wei, Wei, Ma, Guanghui. Macrophage responses to the physical burden of cell-sized particles. JOURNAL OF MATERIALS CHEMISTRY B[J]. 2018, 6(3): 393-400, https://www.webofscience.com/wos/woscc/full-record/WOS:000422871100005.
[54] Xia, Yufei, Wu, Jie, Wei, Wei, Du, Yiqun, Wan, Tao, Ma, Xiaowei, An, Wenqi, Guo, Aiying, Miao, Chunyu, Yue, Hua, Li, Shuoguo, Cao, Xuetao, Su, Zhiguo, Ma, Guanghui. Exploiting the pliability and lateral mobility of Pickering emulsion for enhanced vaccination. NATURE MATERIALS[J]. 2018, 17(2): 187-+, https://www.webofscience.com/wos/woscc/full-record/WOS:000423153800019.
[55] Li, ShaoLu, Hou, Yingqin, Hu, Yali, Yu, Jin, Wei, Wei, Lu, Hua. Phosphatase-triggered cell-selective release of a Pt(IV)-backboned prodrug-like polymer for an improved therapeutic index. BIOMATERIALS SCIENCE[J]. 2017, 5(8): 1558-1566, http://www.irgrid.ac.cn/handle/1471x/1763719.
[56] Wei Wei. Tageted delivery of a guanidine-pendant Pt(IV)-backboned poly-prodrug by an anisamide-functionalized polypeptide. JOURNAL OF MATERIALS CHEMISTRY B. 2017, [57] Li, ShaoLu, Wang, Yaoyi, Zhang, Jingfang, Wei, Wei, Lu, Hua. Targeted delivery of a guanidine-pendant Pt(IV)-backboned poly-prodrug by an anisamide-functionalized polypeptide. JOURNAL OF MATERIALS CHEMISTRY B[J]. 2017, 5(48): 9546-9557, https://www.webofscience.com/wos/woscc/full-record/WOS:000418072200012.
[58] Zhang Lijun, Wei Wei, Ma Guanghui. HSA induced HCPT nanocrystal for high-performance antitumor therapy. Meeting Abstractnull. 2017, 259: E82-, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000407591400140&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=3a85505900f77cc629623c3f2907beab.
[59] Wang, Shuang, Yue, Hua, Xi, Xiaobo, Wei, Wei, Ma, Guanghui. CaCO3-based nano-missile potentiates antigen delivery and cross-presentation. JOURNAL OF CONTROLLED RELEASEnull. 2017, 259: E123-E123, http://dx.doi.org/10.1016/j.jconrel.2017.03.253.
[60] Zhang, Lijun, Wei, Wei, Ma, Guanghui. HSA induced HCPT nanocrystal for high-performance antitumor therapy. JOURNAL OF CONTROLLED RELEASEnull. 2017, 259: E82-E82, http://dx.doi.org/10.1016/j.jconrel.2017.03.181.
[61] Ding, Hui, Zhang, Fan, Zhao, Chaochao, Lv, Yanlin, Ma, Guanghui, Wei, Wei, Tian, Zhiyuan. Beyond a Carrier: Graphene Quantum Dots as a Probe for Programmatically Monitoring Anti-Cancer Drug Delivery, Release, and Response. ACS APPLIED MATERIALS & INTERFACES[J]. 2017, 9(33): 27396-27401, https://www.webofscience.com/wos/woscc/full-record/WOS:000408518800008.
[62] Nana Luo, Jeffrey K Weber, Shuang Wang, Binquan Luan, Hua Yue, Xiaobo Xi, Jing Du, Zaixing Yang, Wei Wei, Ruhong Zhou, Guanghui Ma. PEGylated graphene oxide elicits strong immunological responses despite surface passivation. NATURE COMMUNICATIONS[J]. 2017, 8(1): https://doaj.org/article/a128b2d6b00b4f8f896db220436e5a4a.
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[124] Zhao, YongJiang, Wei, Wei, Su, ZhiGuo, Ma, GuangHui. Poly (ethylene glycol) prodrug for anthracyclines via N-Mannich base linker: Design, synthesis and biological evaluation. INTERNATIONAL JOURNAL OF PHARMACEUTICS[J]. 2009, 379(1): 90-99, http://www.irgrid.ac.cn/handle/1471x/778914.
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[126] Lv, PiPing, Wei, Wei, Gong, FangLing, Zhang, YueLing, Zhao, HuiYing, Lei, JianDu, Wang, LianYan, Ma, GuangHui. Preparation of Uniformly Sized Chitosan Nanospheres by a Premix Membrane Emulsification Technique. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH[J]. 2009, 48(19): 8819-8828, http://www.irgrid.ac.cn/handle/1471x/778910.
[127] Wei, Qiang, Wei, Wei, Tian, Rui, Wang, Lianyan, Su, ZhiGuo, Ma, GuangHui. Preparation of uniform-sized PELA microspheres with high encapsulation efficiency of antigen by premix membrane emulsification. JOURNAL OF COLLOID AND INTERFACE SCIENCE[J]. 2008, 323(2): 267-273, http://dx.doi.org/10.1016/j.jcis.2008.04.058.
[128] Zhang, Yueling, Lian, Guoping, Zhu, Shiping, Wang, Lianyan, Wei, Wei, Ma, Guanghui. Investigation on the uniformity and stability of sunflower oil/water emulsions prepared by a shirasu porous glass membrane. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH[J]. 2008, 47(17): 6412-6417, http://www.irgrid.ac.cn/handle/1471x/725410.
[129] Hao, Dongxia, Gong, Fangling, Wei, Wei, Hu, Guohua, Ma, Guanghui, Su, Zhiguo. Porogen effects in synthesis of uniform micrometer-sized poly(divinylbenzene) microspheres with high surface areas. JOURNAL OF COLLOID AND INTERFACE SCIENCE[J]. 2008, 323(1): 52-59, http://dx.doi.org/10.1016/j.jcis.2008.03.039.
[130] Wei, Qiang, Wei, Wei, Lai, Bo, Wang, LianYan, Wang, YuXia, Su, ZhiGuo, Ma, GuangHui. Uniform-sized PLA nanoparticles: Preparation by premix membrane emulsification. INTERNATIONAL JOURNAL OF PHARMACEUTICS[J]. 2008, 359(1-2): 294-297, http://www.irgrid.ac.cn/handle/1471x/725369.
[131] Shen, Zheyu, Wei, Wei, Zhao, Yonjiang, Ma, Guanghui, Dobashi, Toshiaki, Maki, Yasuyuki, Su, Zhiguo, Wan, Jinpei. Thermosensitive polymer-conjugated albumin nanospheres as thermal targeting anti-cancer drug carrier. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES[J]. 2008, 35(4): 271-282, http://dx.doi.org/10.1016/j.ejps.2008.07.006.
[132] 胡雪, 魏炜, 雷建都, 马光辉, 苏志国, 王化军. T型微通道装置制备尺寸均一壳聚糖微球. 过程工程学报. 2008, 8(1): 130-134, http://lib.cqvip.com/Qikan/Article/Detail?id=26389799.
[133] Qu, JianBo, Zhou, WeiQing, Wei, Wei, Su, ZhiGuo, Ma, GuangHui. Chemical modification and characterization of gigaporous polystyrene microspheres as rapid separation of proteins base supports. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY[J]. 2008, 46(17): 5794-5804, http://www.irgrid.ac.cn/handle/1471x/725324.
[134] Wei, Wei, Yuan, Lan, Hu, Gang, Wang, LianYan, Wu, He, Hu, Xue, Su, ZhiGuo, Ma, GuangHui. Monodisperse chitosan microspheres with interesting structures for protein drug delivery. ADVANCED MATERIALS[J]. 2008, 20(12): 2292-+, http://www.irgrid.ac.cn/handle/1471x/725373.
[135] Qu, JianBo, Zhou, WeiQing, Wei, Wei, Su, ZhiGuo, Ma, GuangHui. An Effective Way To Hydrophilize Gigaporous Polystyrene Microspheres as Rapid Chromatographic Separation Media for Proteins. LANGMUIR[J]. 2008, 24(23): 13646-13652, http://www.irgrid.ac.cn/handle/1471x/725323.
[136] Wei, Wei, Wang, LianYan, Wu, Jie, Ma, GuangHui. Quaternized chitosan microspheres as insulin carrier. JOURNAL OF BIOTECHNOLOGYnull. 2008, 136: S452-S452, http://dx.doi.org/10.1016/j.jbiotec.2008.07.1050.
[137] Bi, Cai Xia, Wei, Wei, Yang, Jian, Gong, Fang Ling, Su, Zhi Guo, Ma, Guang Hui. Uniform one-hole particles used as versatile micro-encapsulation. CHEMISTRY LETTERS[J]. 2008, 37(3): 366-367, http://www.irgrid.ac.cn/handle/1471x/725211.
[138] Wei, Wei, Ma, GuangHui, Hu, Gang, Yu, Di, Mcleish, Tom, Su, ZhiGuo, Shen, ZheYu. Preparation of Hierarchical Hollow CaCO3 Particles and the Application as Anticancer Drug Carrier. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2008, 130(47): 15808-+, http://www.irgrid.ac.cn/handle/1471x/725371.
[139] Wei, Wei, Wang, LianYan, Yuan, Lan, Yang, XiaoDa, Su, ZhiGuo, Ma, GuangHui. Bioprocess of uniform-sized crosslinked chitosan microspheres in rats following oral administration. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS[J]. 2008, 69(3): 878-886, http://dx.doi.org/10.1016/j.ejpb.2008.02.011.
[140] Wu, Jie, Wei, Wei, Wang, LianYan, Su, ZhiGuo, Ma, GuangHui. Preparation of uniform-sized pH-sensitive quaternized chitosan microsphere by combining membrane emulsification technique and thermal-gelation method. COLLOIDS AND SURFACES B-BIOINTERFACES[J]. 2008, 63(2): 164-175, http://dx.doi.org/10.1016/j.colsurfb.2007.11.021.
[141] Wei, Wei, Wang, LianYan, Yuan, Lan, Wei, Qiang, Yang, XiaoDa, Su, ZhiGuo, Ma, GuangHui. Preparation and application of novel microspheres possessing autofluorescent properties. ADVANCED FUNCTIONAL MATERIALS[J]. 2007, 17(16): 3153-3158, http://www.irgrid.ac.cn/handle/1471x/725801.
[142] 王连艳, 魏炜, 马光辉, 苏志国. 尺寸均一、高活性保持的壳聚糖载药微球的制备. 第三届全国化学工程与生物化工年会论文摘要集(下)null. 2006, 1-, http://www.irgrid.ac.cn/handle/1471x/717332.
[143] 吴颉, 魏炜, 马光辉, 苏志国. 新型鼻腔黏膜给药体系的研究. 第三届全国化学工程与生物化工年会论文摘要集(下)null. 2006, 1-, http://www.irgrid.ac.cn/handle/1471x/717346.
[144] 魏炜. 自发荧光壳聚糖纳微球在生物医学领域的探索性研究. 2017第一届天然材料研究与应用研讨会论文集null. 1-, http://ir.ipe.ac.cn/handle/122111/25275.
发表著作
(1) 书籍章节, Preparation and applications of chitosan microsphere ,Current Research and Developments on Chitin and Chitosan in Biomaterial Science, Rangasamy Jayakumar, 2008-01, 第 3 作者
(2) 著作, 激光扫描共聚焦显微镜技术教程, 北京大学医学出版社, 2008-03, 第 3 作者
(3) 著作, 临床药理学原理, 科学出版社, 2008-09, 第 5 作者
(4) 书籍章节, Microsphere for targeting delivery of anticancer drug ,New Microsphere and Microcapsule in Biotechnology: Design, Preparation and Application, Pan Stanford Publishing Pte Ltd., 2013-01, 第 1 作者
(5) 书籍章节, 仿生药物载体的设计、构建和应用 ,分子仿生, 科学出版社, 2013-03, 第 1 作者

科研活动

   
科研项目
( 1 ) 壳聚糖作为疫苗佐剂的深度开发, 主持, 国家级, 2014-01--2016-12
( 2 ) 多佐剂复合型肿瘤全细胞疫苗:设计、构建和应用, 主持, 国家级, 2014-01--2016-12
( 3 ) 免疫原递送微粒载体构建与递呈机制, 主持, 国家级, 2013-01--2017-08
( 4 ) 北京市科技新星计划, 主持, 省级, 2014-07--2017-06
( 5 ) 仿生杆菌研制及其作为肿瘤疫苗佐剂的研究, 主持, 国家级, 2014-01--2016-12
( 6 ) 基于CaCO3颗粒的介尺度结构促进抗原交叉提呈, 主持, 市地级, 2016-01--2018-12
( 7 ) 北京市青年拔尖个人项目, 主持, 省级, 2016-01--2018-12
( 8 ) 仿生纳米药物用于高转移性肿瘤的精准治疗, 主持, 国家级, 2017-07--2022-06
( 9 ) 生物剂型工程的基础研究, 主持, 国家级, 2017-01--2019-12
( 10 ) 基于琼脂糖的高性能分离介质的研究开发, 主持, 国家级, 2018-08--2021-12
参与会议
(1)Biomimetic Formulation Engineering for Anticancer Therapy   2019-12-19
(2)仿生纳米剂型工程及其在抗肿瘤中的应用   中美全球双边健康研讨会   2019-12-11
(3)Biomimetic Formulation Engineering for Anticancer Therapy   2019-10-22
(4)Biomimetic Formulation Engineering for Anticancer Therapy   2019-09-24
(5)仿生抗肿瘤剂型工程   2019中国肿瘤学大会   2019-08-16
(6)仿生抗肿瘤剂型工程   中国化学会第17届全国胶体与界面化学学术会议   2019-07-28
(7)仿生抗肿瘤剂型工程   肝硬化门脉高压的无创评价及介入治疗新进展研讨班暨同仁消化春季高峰论坛   2019-05-24
(8)仿生抗肿瘤剂型工程   2018化工学科前沿青年学者论坛   2018-11-30
(9)Materials-based Safe & High-performance Vaccines for Clinical Use   2018-11-15
(10)Materials-based Safe & High-performance Vaccines for Clinical Use    中国工程院国际高端论坛—2018医学免疫与临床应用高峰论坛   2018-11-02
(11)Graphene’s unique nano-bio interface effects and potential applications   2018-10-18
(12)Graphene’s unique nano-bio interface effects and potential applications   2018-10-15
(13)石墨烯独特的纳米-生物界面效应及其潜在应用   中国化学会第31届学术年会“纳米生物效应与纳米药物化学”分会   2018-05-04
(14)Material-based High-performance Vaccines Potentiate Antitumor Therapy   2018疫苗创新国际论坛   2018-04-18
(15)仿生纳米剂型工程及其在抗肿瘤中的应用   中国生物工程学会第三届青年科技论坛   2018-04-13
(16)石墨烯独特的纳米-生物界面效应及其潜在应用   2017年中国生物物理学会纳米生物学分会学术年会暨首届纳米生物医学交叉论坛   2017-11-18
(17)Material-based High-performance Vaccines Potentiate Antitumor Therapy   第六届首都国际癌症论坛   2017-11-09
(18)Pharmaceutical Applications of Uniform-sized Chitosan Micro/Nanospheres with Autofluorescent Property   2017第八届中日化工学术研讨会   2017-10-14
(19)Pharmaceutical Applications of Uniform-sized Chitosan Micro/Nanospheres with Autofluorescent Property   中国生物工程学会第十一届学术年会暨2017年全国生物技术大会   2017-09-23
(20)石墨烯独特的纳米-生物界面效应及其潜在应用   2017-09-02
(21)Pharmaceutical Applications of Uniform-sized Chitosan Micro/Nanospheres with Autofluorescent Property   2017-08-14
(22)仿生纳米剂型工程及其在抗肿瘤治疗中的应用   第九届全球华人化工学者研讨会   2017-07-18
(23)石墨烯独特的纳米-生物界面效应及其潜在应用   中国材料大会2017暨银川国际材料周   2017-07-06
(24)石墨烯独特的纳米-生物界面效应及其潜在应用   第一届能源化学与材料国际青年论坛暨中科院青年创新促进会化学与材料分会 2017 学术年会   2017-05-02
(25)Materials-based Safe & High-performance Vaccines    上海国际生物技术与医药研讨会   2016-06-20

指导学生

现指导学生

胡校铭  博士研究生  081703-生物化工  

栗锋  博士研究生  081703-生物化工  

丁昭文  硕士研究生  081703-生物化工