基本信息
魏平 男 博导 中国科学院深圳先进技术研究院
电子邮件: ping.wei@siat.ac.cn
通信地址: 深圳西丽深圳大学城学苑大道1068
邮政编码: 518055
研究领域
主要研究方向包括:
细胞与基因线路的设计原理研究、人工合成技术及合成生物学设计软件开发;结合蛋白质工程、免疫与细胞工程方法,开发靶向复杂疾病的细胞与基因治疗的技术与应用方法。
招生信息
面向分子与细胞生物学、免疫学、物理化学、物理生物学等各种背景的本科生。
招生专业
071009-细胞生物学071010-生物化学与分子生物学071011-生物物理学
招生方向
定量合成生物学细胞与基因线路工程,蛋白质工程细胞与基因治疗
教育背景
2002-09--2007-07 北京大学 理学博士1998-09--2002-07 南开大学 理学学士
出版信息
发表论文
[1] Mathias S Heltberg, Yuanxu Jiang, Yingying Fan, Zhibo Zhang, Malthe S Nordentoft, Wei Lin, Long Qian, Qi Ouyang, Mogens H Jensen, Ping Wei. Coupled oscillator cooperativity as a control mechanism in chronobiology. CELL SYSTEMS. 2023, 14(5): 382-391.e5, http://dx.doi.org/10.1016/j.cels.2023.04.001.[2] Wen Si, YingYing Fan, ShiZhen Qiu, Xin Li, ErYi Wu, JianQi Ju, Wen Huang, HaoPeng Wang, Ping Wei. Design of diversified chimeric antigen receptors through rational module recombination. ISCIENCE[J]. 2023, 26(4): 106529-, http://dx.doi.org/10.1016/j.isci.2023.106529.[3] Qiao, Lingxia, Zhang, ZhiBo, Zhao, Wei, Wei, Ping, Zhang, Lei. Network design principle for robust oscillatory behaviors with respect to biological noise. ELIFE[J]. 2022, 11: http://dx.doi.org/10.7554/eLife.76188.[4] Tang, Rui, Fu, YuHao, Gong, Bo, Fan, YingYing, Wang, HongHui, Huang, Yan, Nie, Zhou, Wei, Ping. A Chimeric Conjugate of Antibody and Programmable DNA Nanoassembly Smartly Activates T Cells for Precise Cancer Cell Targeting. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2022, http://dx.doi.org/10.1002/anie.202205902.[5] Li, Wentao, Qiu, Shizhen, Chen, Jian, Jiang, Shutan, Chen, Wendong, Jiang, Jingwei, Wang, Fei, Si, Wen, Shu, Yilai, Wei, Ping, Fan, Gaofeng, Tian, Ruijun, Wu, Haitao, Xu, Chenqi, Wang, Haopeng. Chimeric Antigen Receptor Designed to Prevent Ubiquitination and Downregulation Showed Durable Antitumor Efficacy. IMMUNITY[J]. 2020, 53(2): 456-+, http://dx.doi.org/10.1016/j.immuni.2020.07.011.[6] Si, Wen, Li, Cheng, Wei, Ping. Synthetic immunology: T-cell engineering and adoptive immunotherapy. SYNTHETIC AND SYSTEMS BIOTECHNOLOGY[J]. 2018, 3(3): 179-185, http://lib.cqvip.com/Qikan/Article/Detail?id=7103844760.[7] Zhang ZhiBo, Wang QiuYue, Ke YuXi, Liu ShiYu, Ju JianQi, Lim Wendell A, Tang Chao, Wei Ping. Design of Tunable Oscillatory Dynamics in a Synthetic NF-κB Signaling Circuit. CELL SYSTEMS[J]. 2017, 5(5): 460-470.e5, http://dx.doi.org/10.1016/j.cels.2017.09.016.[8] Mitchell, Amir, Wei, Ping, Lim, Wendell A. Oscillatory stress stimulation uncovers an Achilles' heel of the yeast MAPK signaling network. SCIENCE[J]. 2015, 350(6266): 1379-1383, https://www.webofscience.com/wos/woscc/full-record/WOS:000366162400043.
科研活动
科研项目
( 1 ) 基因回路在精准诊断和靶向治疗膀胱癌中的应用研究, 参与, 国家级, 2019-01--2023-12( 2 ) 人工基因回路设计、构建及其用于代谢疾病智能诊疗的研究, 参与, 国家级, 2020-01--2024-12