070302-分析化学

中药药效物质基础；中药先进制造工艺与二次开发；中药资源利用与大健康产品开发

2007-09--2013-03   中科院大连化学物理研究所   分析化学博士
2003-09--2007-07   浙江大学药学院   理学学士

   

2020-10~现在, 中科院大连化学物理研究所, 课题组长
2019-04~现在, 中科院大化所中国医药城生物医药创新研究院, 副院长
2016-09~2019-03,中科院大化所中国医药城生物医药创新研究院, 院长助理
2015-07~现在, 中科院大连化学物理研究所, 副研究员
2013-03~2015-07,中科院大连化学物理研究所, 助理研究员

   

[1] 梁鑫淼, 赵耀鹏, 刘艳芳, 王纪霞, 王长健, 王志伟, 杜娜娜, 张秀莉, 郭志谋, 王超然. 一种2-(2,2-二芳基乙基)-环胺衍生物或盐及合成和应用与组合物. CN: CN110372571A, 2019-10-25.

[2] 梁鑫淼, 张鹏宇, 张秀莉, 王纪霞, 刘艳芳, 王超然, 周维佳. β 2 -肾上腺素受体拮抗剂及应用. CN: CN109893651A, 2019-06-18.

[3] 梁鑫淼, 王超然, 郭秀洁, 张秀莉, 郭志谋, 薛兴亚. 一种延胡索提取物中叔胺碱和季铵碱的分类制备方法. CN: CN104415573A, 2015-03-18.

[4] 梁鑫淼, 王超然, 郭秀洁, 张秀莉, 郭志谋, 薛兴亚. 一种延胡索提取物中叔胺碱和季铵碱的分类制备方法. CN: CN104415573A, 2015-03-18.

[5] 梁鑫淼, 龙珍, 张秀莉, 王超然, 郭志谋. 一种强极性碱性化合物的分离分析或分离制备方法. CN: CN103878036A, 2014-06-25.

[6] 梁鑫淼, 王超然, 张秀莉, 张岩, 王志伟, 奥利维尔·希维利, 柯燕雄, 王藜恩. 小檗碱类化合物的用途和制备方法. CN: CN103816152A, 2014-05-28.

[7] 梁鑫淼, 龙珍, 张秀莉, 王超然, 郭志谋. 一种山莨菪中生物碱的前处理方法. CN: CN102850343A, 2013-01-02.

[8] 梁鑫淼, 郭志谋, 沈爱金, 王超然. 一种强阳离子交换色谱固定相及其制备方法. CN: CN102614845A, 2012-08-01.

[9] 周嘉伟, 梁鑫淼, 彭海蓉, 赵耀鹏, 王昊然, 王超然, 尹延青, 刘艳芳, 陈巧喻, 张彧锴. 肠道菌群调节剂在制备治疗脑部神经疾病的药物中的用途. 202311420622.5, 2023-10-30.

[10] 梁鑫淼, 周晗, 侯滔, 王超然, 王纪霞. 化合物作为或制备多巴胺受体拮抗剂中的应用及拮抗剂. CN: CN114539145A, 2022-05-27.

   

[1] 余文怡, 伍慧敏, 郭秀洁, 闫淑梅, 刘湘杰, 王竹君, 王超然, 沈爱金, 梁鑫淼. 基于超高效液相色谱-四极杆-静电场轨道阱高分辨质谱的刺五加注射液化学成分分析. 色谱[J]. 2023, 第 7 作者  通讯作者  41(3): 207-223, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=7425215&detailType=1.
[2] Zhao, Yaopeng, Wang, Jixia, Hou, Tao, Yu, Yancheng, Zhou, Han, Han, Yang, Cheng, Junxiang, Liu, Yanfang, Wang, Chaoran, Chen, Long, Liang, Xinmiao. Design and synthesis of 2-(2,2-diarylethyl)-cyclamine derivatives as M3 receptor antagonists and functional evaluation on COPD. BIOORGANIC CHEMISTRY[J]. 2023, 第 9 作者131: http://dx.doi.org/10.1016/j.bioorg.2022.106308.
[3] Xinwei Zhao, Tao Hou, Han Zhou, Ziling Liu, Yanfang Liu, Chaoran Wang, Zhimou Guo, Dongping Yu, Qing Xu, Jixia Wang, Xinmiao Liang. Multi-effective components and their target mechanism of Ziziphi Spinosae Semen in the treatment of insomnia. FITOTERAPIA. 2023, 第 6 作者171: http://dx.doi.org/10.1016/j.fitote.2023.105712.
[4] Zhao, Xinwei, Yu, Dongping, Zhou, Weijia, Yu, Long, Zhou, Han, Liu, Yanfang, Guo, Zhimou, Shen, Aijing, Han, Ziwei, Wang, Chaoran, Wang, Jixia, Liang, Xinmiao. Chemical profiling of Ziziphi spinosae semen using on-line comprehensive two-dimensional liquid chromatography-mass spectrometry based on a novel phthalic anhydride bonded stationary phase. JOURNAL OF SEPARATION SCIENCE[J]. 2023, 第 10 作者46(10): http://dx.doi.org/10.1002/jssc.202200704.
[5] 王豪, 王委, 刘艳芳, 郭志谋, 王超然. 普洱大叶茶中对褪黑素受体具有激动作用的活性化合物. 天然产物研究与开发[J]. 2022, 第 5 作者34(6): 1021-1026, http://lib.cqvip.com/Qikan/Article/Detail?id=7107486712.
[6] Liu Wei, Huang Han, Zhang Feng, Zhang CongCong, Li RongSheng, Wang YongLi, Wang ChaoRan, Liang XinMiao, Zhang WeiDong, Yang Ling, Liu Ping, Ge GuangBo. Comprehensive profiling and characterization of the absorbed components and metabolites in mice serum and tissues following oral administration of Qing-Fei-Pai-Du decoction by UHPLC-Q-Exactive-Orbitrap HRMS. CHINESE JOURNAL OF NATURAL MEDICINES[J]. 2021, 第 7 作者19(4): 305-320, http://lib.cqvip.com/Qikan/Article/Detail?id=7104641043.
[7] 戚华文, 徐鑫, 温柔, 高德嵩, 王超然, 刘艳芳, 金红利, 梁鑫淼. 基于化学模式识别技术的枳实HPLC定量指纹图谱研究. 分析测试学报[J]. 2021, 第 5 作者40(1): 72-78, http://lib.cqvip.com/Qikan/Article/Detail?id=7104183319.
[8] Zhou, QiHang, Qin, WeiWei, Finel, Moshe, He, QingQing, Tu, DongZhu, Wang, ChaoRan, Ge, GuangBo. A broad-spectrum substrate for the human UDP-glucuronosyltransferases and its use for investigating glucuronidation inhibitors. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2021, 第 6 作者180: 252-261, http://dx.doi.org/10.1016/j.ijbiomac.2021.03.073.
[9] Sun Lingli, Liu Jia, Guo Xiujie, Wu Lidong, Duan Zhengchao, Wang Chaoran, Wang Lianzhi. Hydrophilic interaction liquid chromatography for removal of pesticide residues in ginseng extracts. CHINESE JOURNAL OF CHROMATOGRAPHY[J]. 2021, 第 6 作者  通讯作者  39(4): 444-452, 
[10] Xu, Fangfang, Wang, Pan, Zhang, Xiuli, Hou, Tao, Qu, Lala, Wang, Chaoran, Wang, Jixia, Liu, Yanfang, Liang, Xinmiao. Identification and target-pathway deconvolution of FFA4 agonists with anti-diabetic activity from Arnebia euchroma (Royle) Johnst. PHARMACOLOGICAL RESEARCH[J]. 2021, 第 6 作者163: http://dx.doi.org/10.1016/j.phrs.2020.105173.
[11] 孙伶俐, 刘佳, 郭秀洁, 吴立冬, 段正超, 王超然, 王联芝. 亲水作用液相色谱脱除人参提取物中农药残留. 色谱[J]. 2021, 第 6 作者39(4): 444-452, http://lib.cqvip.com/Qikan/Article/Detail?id=7104250232.
[12] Zhang, Feng, Huang, Jian, Liu, Wei, Wang, ChaoRan, Liu, YanFang, Tu, DongZhu, Liang, XinMiao, Yang, Ling, Zhang, WeiDong, Chen, HongZhuan, Ge, GuangBo. Inhibition of drug-metabolizing enzymes by Qingfei Paidu decoction: Implication of herb-drug interactions in COVID-19 pharmacotherapy. FOOD AND CHEMICAL TOXICOLOGY[J]. 2021, 第 4 作者149: 111998-111998, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816587/.
[13] 郭秀洁, 李昊虬, 冯昊天, 戚华文, 张露, 徐伟, 伍言娟, 王超然, 梁鑫淼. 基于高效液相色谱定量指纹图谱和液相色谱-质谱联用定量的酸枣仁提取物质量考察. 色谱[J]. 2021, 第 8 作者39(9): 989-997, http://lib.cqvip.com/Qikan/Article/Detail?id=7105466361.
[14] Li, Yuyuan, Liu, He, Qi, Huawen, Tang, Wei, Zhang, Caihua, Liu, Zhaiyi, Liu, Yinhui, Wei, Xiaoqing, Kong, Zhen, Jia, Shangyi, Du, Borong, Yuan, Jieli, Wang, Chaoran, Li, Ming. Probiotic fermentation of Ganoderma lucidum fruiting body extracts promoted its immunostimulatory activity in mice with dexamethasone-induced immunosuppression. BIOMEDICINE & PHARMACOTHERAPY[J]. 2021, 第 13 作者  通讯作者  141: https://doaj.org/article/fb3bb07f8c9f4e03a57ebfd6478ed9fa.
[15] 戚华文, 徐鑫, 高德嵩, 王引, 金红利, 王超然, 刘艳芳, 梁鑫淼. 吴茱萸HPLC指纹图谱的建立及基原鉴别研究. 中草药[J]. 2021, 第 6 作者52(14): 4341-4347, http://lib.cqvip.com/Qikan/Article/Detail?id=7105348269.
[16] He, QingQing, Chen, Yue, Zhou, QiHang, Zhang, Feng, Wang, YiNan, Wang, ChaoRan, He, YuQi, Liang, XinMiao, Ge, GuangBo, Yang, Ling. Deciphering the metabolic fates of a green fluorescent protein (GFP)-like fluorophore: Metabolite identification, isoenzyme contribution and species differences. DYES AND PIGMENTS[J]. 2020, 第 6 作者181: http://dx.doi.org/10.1016/j.dyepig.2020.108571.
[17] 孙伶俐, 刘佳, 郭秀洁, 段正超, 王超然, 王联芝. 人参中农药残留现状及脱除工艺研究. 广东化工[J]. 2020, 第 5 作者47(17): 89-90+82, http://lib.cqvip.com/Qikan/Article/Detail?id=7103136231.
[18] 高振华, 王超然, 郭秀洁, 王纪霞, 郭志谋, 王联芝. 延胡索中叔胺碱和季铵碱类组分的高效分离及镇痛活性鉴定. 天然产物研究与开发[J]. 2020, 第 2 作者32(3): 507-514+419, https://kns.cnki.net/KCMS/detail/detail.aspx?dbcode=CJFQ&dbname=CJFDLAST2020&filename=TRCW202003021&v=Mjc2NjBNVC9JZWJHNEhOSE1ySTlIWllSOGVYMUx1eFlTN0RoMVQzcVRyV00xRnJDVVI3cWVadWR1RnlIblZMck0=.
[19] 吴高松, 钟婧, 郑宁宁, 王超然, 金红利, 葛广波, 韩晶岩, 高月, 盛丽莉, 张卫东, 李后开. 清肺排毒汤对大鼠整体代谢及肠道菌群的调节作用研究. 中国中药杂志[J]. 2020, 第 4 作者45(15): 3726-3739, http://lib.cqvip.com/Qikan/Article/Detail?id=7102688105.
[20] 徐鑫, 戚华文, 高德嵩, 蔡新娜, 金磊, 金红利, 王超然, 刘艳芳, 梁鑫淼. 基于化学模式识别的栀子UPLC定量指纹图谱研究. 中国中药杂志[J]. 2020, 第 7 作者45(18): 4416-4422, http://lib.cqvip.com/Qikan/Article/Detail?id=7103202362.
[21] 高振华, 孙伶俐, 王豪, 王超然, 王联芝. 荷叶化学成分及其药理活性研究. 广东化工[J]. 2020, 第 4 作者47(5): 100-102, https://kns.cnki.net/KCMS/detail/detail.aspx?dbcode=CJFQ&dbname=CJFDLAST2020&filename=GDHG202005041&v=MjU0MzhyQklpbkRhYkc0SE5ITXFvOUJaWVI4ZVgxTHV4WVM3RGgxVDNxVHJXTTFGckNVUjdxZVp1ZHVGeUhuV3I=.
[22] Guo, Xiujie, Gao, Zhenhua, Wang, Jixia, Guo, Zhimou, Zhang, Xiuli, Liu, Yanfang, Wang, Lianzhi, Wang, Chaoran, Liang, Xinmiao. Purification of tertiary and quaternary alkaloids from Rhizoma Corydalis using reversed-phase/weak cation-exchange mixed-mode class separation combined with preparative C18 and silica based strong cation-exchange chromatography. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES[J]. 2019, 第 8 作者  通讯作者  1126: http://dx.doi.org/10.1016/j.jchromb.2019.121742.
[23] 王荣, 刘艳芳, 王超然, 郭志谋, 梁鑫淼. 生物碱的高效液相色谱分离分析与纯化制备研究进展. 分析测试学报[J]. 2019, 第 3 作者38(5): 586-594, http://lib.cqvip.com/Qikan/Article/Detail?id=7001943909.
[24] 项婷, 夏琛, 沈建福, 王超然. 蛹虫草中抗肿瘤活性成分及作用机制研究进展. 食品与营养科学[J]. 2019, 第 4 作者8(4): 258-266, http://lib.cqvip.com/Qikan/Article/Detail?id=HS724232019004006.
[25] Wang, Lien, Zhang, Yan, Wang, Chaoran, Zhang, Xiuli, Wang, Zhiwei, Liang, Xinmiao, Alachkar, Amal, Civelli, Olivier. A Natural Product with High Affinity to Sigma and 5-HT7 Receptors as Novel Therapeutic Drug for Negative and Cognitive Symptoms of Schizophrenia. NEUROCHEMICAL RESEARCH[J]. 2019, 第 3 作者44(11): 2536-2545, https://www.webofscience.com/wos/woscc/full-record/WOS:000492663200009.
[26] Du, Nana, Si, Wei, Liu, Yanfang, Guo, Zhimou, Zhou, Weijia, Zhou, Han, Liang, Xinmiao, Wang, Chaoran. Strong electrostatic repulsive interaction used for fast and effective alkaloid enrichment from plants. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES[J]. 2019, 第 8 作者1105: 148-155, http://www.corc.org.cn/handle/1471x/2372875.
[27] Wu, Lehao, Zhang, Weiyue, Qiu, Xin, Wang, Chaoran, Liu, Yanfang, Wang, Zhiwei, Yu, Yang, Ye, Richard D, Zhang, Yan. Identification of Alkaloids from Corydalis yanhusuo W. T. Wang as Dopamine D-1 Receptor Antagonists by Using CRE-Luciferase Reporter Gene Assay. MOLECULES[J]. 2018, 第 4 作者23(10): http://cas-ir.dicp.ac.cn/handle/321008/166562.
[28] Zhang, Pengyu, Wang, Jixia, Zhao, Ying, Zhang, Xiuli, Qu, Lala, Wang, Chaoran, Feng, Jiatao, Wang, Anhui, Zhou, Weijia, Liu, Yanfang, Hou, Tao, Zhou, Han, Wang, Zhiwei, Liang, Xinmiao. Discovery of novel antagonists on beta(2)-adrenoceptor from natural products using a label-free cell phenotypic assay. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY[J]. 2018, 第 6 作者391(12): 1411-1420, https://www.webofscience.com/wos/woscc/full-record/WOS:000448849700010.
[29] Zhou, Weijia, Guo, Zhimou, Yu, Long, Zhou, Han, Shen, Aijin, Jin, Yan, Jin, Gaowa, Yan, Jingyu, Yang, Fan, Liu, Yanming, Wang, ChaoRan, Feng, JiaTao, Liu, Yanfang, Liang, Xinmiao. On-line comprehensive two-dimensional liquid chromatography tandem mass spectrometry for the analysis of Curcuma kwangsiensis. TALANTA[J]. 2018, 第 11 作者186: 73-79, http://dx.doi.org/10.1016/j.talanta.2018.04.014.
[30] Jin, Hongli, Liu, Yanfang, Guo, Zhimou, Wang, Jixia, Zhang, Xiuli, Wang, Chaoran, Liang, Xinmiao. Recent development in liquid chromatography stationary phases for separation of Traditional Chinese Medicine components. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS[J]. 2016, 第 6 作者130: 336-346, http://dx.doi.org/10.1016/j.jpba.2016.06.008.
[31] Jin, Gaowa, Guo, Zhimou, Xiao, Yuansheng, Yan, Jingyu, Dong, Xuefang, Shen, Aijin, Wang, Chaoran, Liang, Xinmiao. Practical method for the definition of chromatographic peak parameters in preparative liquid chromatography. JOURNAL OF SEPARATION SCIENCE[J]. 2016, 第 7 作者39(20): 3917-3926, http://cas-ir.dicp.ac.cn/handle/321008/150411.
[32] Wang, Lien, Zhang, Yan, Wang, Zhiwei, Gong, Nian, Kweon, Tae Dong, Vo, Benjamin, Wang, Chaoran, Zhang, Xiuli, Chung, Jae Yoon, Alachkar, Amal, Liang, Xinmiao, Luo, David Z, Civelli, Olivier. The Antinociceptive Properties of the Corydalis yanhusuo Extract. PLOS ONE[J]. 2016, 第 7 作者11(9): http://cas-ir.dicp.ac.cn/handle/321008/169966.
[33] 张岩, 王超然, 郭志谋, 张秀莉, ZhiweiWang, 梁鑫淼, OlivierCivelli. Discovery of N—methyltetrahydroprotoberberines with κ—opioid receptor agonists—opioid receptor agonist activities from corydalis yanhusuo W.T.Wang by using two—dimensional liquid chromatography. JOURNAL OF ETHNOPHARMACOLOGY[J]. 2015, 第 2 作者155(3): 1597, http://cas-ir.dicp.ac.cn/handle/321008/144339.
[34] Li, Xiaolong, Guo, Zhimou, Wang, Chaoran, Shen, Aijin, Liu, Yanfang, Zhang, Xiuli, Zhao, Weijie, Liang, Xinmiao. Purification of bufadienolides from the skin of Bufo bufo gargarizans Cantor with positively charged C18 column. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS[J]. 2014, 第 3 作者92: 105-113, http://dx.doi.org/10.1016/j.jpba.2014.01.002.
[35] Li, Xiaolong, Liu, Yanfang, Shen, Aijin, Wang, Chaoran, Yan, Jingyu, Zhao, Weijie, Liang, Xinmiao. Efficient purification of active bufadienolides by a class separation method based on hydrophilic solid-phase extraction and reversed-phase high performance liquid chromatography. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS[J]. 2014, 第 4 作者97: 54-64, http://dx.doi.org/10.1016/j.jpba.2014.04.015.
[36] Wang, Jixia, Wang, Chaoran, Guo, Zhimou, Dong, Xuefang, Xiao, Yuansheng, Xue, Xingya, Zhang, Xiuli, Liang, Xinmiao. A novel method for characterization and comparison of reversed-phase column selectivity. JOURNAL OF CHROMATOGRAPHY A[J]. 2014, 第 2 作者1361(1): 153-161, http://dx.doi.org/10.1016/j.chroma.2014.08.005.
[37] 张岩, 张秀莉, 王超然, 薛兴亚, 梁鑫淼. GPCR-based drug discovery from Traditional Chinese Medicine. 2014 Shanghai international conference on traditional chinese medicine and natural medicine. 2014, 第 3 作者http://cas-ir.dicp.ac.cn/handle/321008/143504.
[38] Zhang, Yan, Wang, Chaoran, Wang, Lien, Parks, Gregory Scott, Zhang, Xiuli, Guo, Zhimou, Ke, Yanxiong, Li, KangWu, Kim, Mi Kyeong, Vo, Benjamin, Borrelli, Emiliana, Ge, Guangbo, Yang, Ling, Wang, Zhiwei, GarciaFuster, M Julia, Luo, Z David, Liang, Xinmiao, Civelli, Olivier. A Novel Analgesic Isolated from a Traditional Chinese Medicine. CURRENT BIOLOGY[J]. 2014, 第 2 作者24(2): 117-123, http://dx.doi.org/10.1016/j.cub.2013.11.039.
[39] Zhang, Yan, Wang, Chaoran, Guo, Zhimou, Zhang, Xiuli, Wang, Zhiwei, Liang, Xinmiao, Civelli, Olivier. Discovery of N-methyltetrahydroprotoberberines with kappa-opioid receptor agonists-opioid receptor agonist activities from corydalis yanhusuo W. T. Wang by using two-dimensional liquid chromatography. JOURNAL OF ETHNOPHARMACOLOGY[J]. 2014, 第 2 作者155(3): 1597-1602, http://cas-ir.dicp.ac.cn/handle/321008/145544.
[40] Wang, Chaoran, Guo, Zhimou, Long, Zhen, Zhang, Xiuli, Liang, Xinmiao. Overloading study of basic compounds with a positively charged C18 column in liquid chromatography. JOURNAL OF CHROMATOGRAPHY A[J]. 2013, 第 1 作者1281: 60-66, http://dx.doi.org/10.1016/j.chroma.2013.01.074.
[41] Jin, Hongli, Liu, Yanfang, Feng, Jiatao, Guo, Zhimou, Wang, Chaoran, Zhong, Zhengsheng, Peng, Xiaojun, Dang, Jun, Tao, Yanduo, Liang, Xinmiao. Efficient purification of high-purity compounds from the stem of Lonicera japonica Thunb using two-dimensional preparative chromatography. JOURNAL OF SEPARATION SCIENCE[J]. 2013, 第 5 作者36(15): 2414-2420, http://www.irgrid.ac.cn/handle/1471x/721003.
[42] Zhang, Xiuli, Liu, Yanfang, Guo, Zhimou, Feng, Jiatao, Dong, Jun, Fu, Qing, Wang, Chaoran, Xue, Xingya, Xiao, Yuansheng, Liang, Xinmiao. The herbalome-an attempt to globalize Chinese herbal medicine. ANALYTICAL AND BIOANALYTICAL CHEMISTRY[J]. 2012, 第 7 作者402(2): 573-581, http://159.226.238.44/handle/321008/142856.
[43] 梁鑫淼, 刘艳芳, 王超然, 许俊彦, 薛兴亚, 张秀莉. Natural products purification and drug discovery. THE 6TH SHANGHAI INTERNATIONAL SYMPOSIUM ON ANALYTICAL CHEMISTRY. 2012, 第 3 作者72, http://159.226.238.44/handle/321008/116955.
[44] Long, Zhen, Wang, Chaoran, Guo, Zhimou, Zhang, Xiuli, Nordahl, Lilly, Zeng, Jing, Zeng, Jianguo, Liang, Xinmiao. A non-aqueous solid phase extraction method for alkaloid enrichment and its application in the determination of hyoscyamine and scopolamine. ANALYST[J]. 2012, 第 2 作者137(6): 1451-1457, http://www.irgrid.ac.cn/handle/1471x/721748.
[45] Long, Zhen, Wang, Chaoran, Guo, Zhimou, Zhang, Xiuli, Nordahl, Lilly, Liang, Xinmiao. Strong cation exchange column allow for symmetrical peak shape and increased sample loading in the separation of basic compounds. JOURNALOFCHROMATOGRAPHYA[J]. 2012, 第 2 作者1256: 67-71, http://dx.doi.org/10.1016/j.chroma.2012.07.008.
[46] Wang, Chaoran, Guo, Zhimou, Zhang, Jing, Zeng, Jing, Zhang, Xiuli, Liang, Xinmiao. High-performance purification of quaternary alkaloids from Corydalis yanhusuo W. T. Wang using a new polar-copolymerized stationary phase. JOURNAL OF SEPARATION SCIENCE[J]. 2011, 第 1 作者34(1): 53-58, http://www.irgrid.ac.cn/handle/1471x/456723.
[47] 王超然, 杜娜娜, 郭志谋, 张秀莉, 梁鑫淼. Separation of structurally similar protoberberine alkaloids from Corydalis yanhusuo W.T.Wang in reversed-phase high-performance liquid chromatography with chaotropic salts. 37TH INTERNATIONAL SYMPOSIUM ON HIGH PERFORMANCE LIQUID PHASE SEPARATIONS AND RELATED TECHNIQUES　. 2011, 第 1 作者583, http://159.226.238.44/handle/321008/117249.
[48] Cai, Xiaoming, Wang, Chaoran, Xu, Junyan, Xue, Xingya, Zhang, Xiuli, Liang, Xinmiao. Application of matrix solid-phase dispersion methodology to the extraction of endogenous peptides from porcine hypothalamus samples for MS and LC-MS analysis. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES[J]. 2011, 第 2 作者879(9-10): 657-661, http://dx.doi.org/10.1016/j.jchromb.2011.01.038.
[49] 郭志谋, 王超然, 蔡晓明, 董军, 梁鑫淼. Separation Materials Based on Polar-copolymerized Approach. 37TH INTERNATIONAL SYMPOSIUM ON HIGH PERFORMANCE LIQUID PHASE SEPARATIONS AND RELATED TECHNIQUES. 2011, 第 2 作者227, http://159.226.238.44/handle/321008/117256.
[50] Xiaoming Cai, Chaoran Wang, Junyan Xu, Xingya Xue, Xiuli Zhang, Xinmiao Liang. Application of matrix solid-phase dispersion methodology to the extraction of endogenous peptides from porcine hypothalamus samples for MS and LC–MS analysis. JOURNAL OF CHROMATOGRAPHY B[J]. 2011, 第 2 作者879(9): 657-661, http://dx.doi.org/10.1016/j.jchromb.2011.01.038.
[51] 龙真, 王超然, 郭志谋, 郭秀洁, 张秀莉, 梁鑫淼. Development and validation of a solid phase extraction method for the enrichment of alkaloids enabling the preparation of alkaloids from Scopolia tangutica Maxim. 37TH INTERNATIONAL SYMPOSIUM ON HIGH-PERFORMANCE LIQUID PHASE SEPARATIONS AND RELATED TECHNIQUES. 2011, 第 2 作者359, http://159.226.238.44/handle/321008/117254.
[52] 曾静, 郭志谋, 李伟, 王超然, 张秀莉, 梁鑫淼. 离线二维液相色谱-串联质谱法检测姜黄中姜黄素类和倍半萜类化合物. 中国科学：化学[J]. 2010, 第 4 作者768-774, http://lib.cqvip.com/Qikan/Article/Detail?id=34335914.
[53] Zeng, Jing, Guo, Zhimou, Xiao, Yuansheng, Wang, Chaoran, Zhang, Xiuli, Liang, Xinmiao. Purification of polar compounds from Radix isatidis using conventional C18 column coupled with polar-copolymerized C18 column. JOURNAL OF SEPARATION SCIENCE[J]. 2010, 第 4 作者33(21): 3341-3346, http://159.226.238.44/handle/321008/141772.
[54] Guo, Zhimou, Wang, Chaoran, Liang, Tu, Liang, Xinmiao. Polar-copolymerized approach based on horizontal polymerization on silica surface for preparation of polar-modified stationary phases. JOURNAL OF CHROMATOGRAPHY A[J]. 2010, 第 2 作者1217(27): 4555-4560, http://dx.doi.org/10.1016/j.chroma.2010.04.068.
[55] 曾静, 郭志谋, 张秀莉, 肖远胜, 王超然, 薛兴亚, 梁鑫淼. 离线二维液相色谱-质谱分离鉴定板蓝根中的微量化合物. The 24th international symposium on microscale bioseparations. 2009, 第 5 作者272/1, http://159.226.238.44/handle/321008/113896.
[56] 刘艳芳, 刘艳明, 董军, 李伟, 王超然, 张秀莉, 梁鑫淼. 中药物质基础的高效液相色谱分离分析方法研究. 中国科学：B辑[J]. 2009, 第 5 作者678-686, http://lib.cqvip.com/Qikan/Article/Detail?id=31432348.
[57] 郭志谋, 梁图, 蔡晓明, 曾静, 王超然, 梁鑫淼. 基于表面水平聚合的极性/非极性共聚固定相制备. 24th international symposium on microscale bioseparations. 2009, 第 5 作者272/1, http://159.226.238.44/handle/321008/113892.
[58] 刘艳芳, 刘艳明, 董军, 李伟, 王超然, 张秀莉, 梁鑫淼. 中药物质基础的高效液相色谱分离分析方法研究. 中国科学 B[J]. 2009, 第 5 作者39(8): 678-686, http://159.226.238.44/handle/321008/102753.
[59] 郭志谋, 梁图, 蔡晓明, 曾静, 王超然, 梁鑫淼. One-step process for preparation of polar/non-polar copolymerized stationary phases by using surface horizontal polymerization. 24th international symposium on microscale bioseparations. 2009, 第 5 作者272/1, http://159.226.238.44/handle/321008/113892.
[60] 曾静, 郭志谋, 张秀莉, 肖远胜, 王超然, 薛兴亚, 梁鑫淼. Identification and Characterization of the low-abundant constituents of Radix isatidis by off-line 2D-LC coupled with Q-TOF MS. The 24th international symposium on microscale bioseparations. 2009, 第 5 作者272/1, http://159.226.238.44/handle/321008/113896.

   

（ 1 ） 基于表面正电荷型反相固定相的碱性化合物色谱分离研究, 负责人, 国家任务, 2015-01--2017-12