Ethnobotany
Medicinal Chemistry

From 9/2003 to 7/2006: Kunming Institute of Botany, Chinese Academy of Sciences; Ph.D. in Botany (Phytochemistry)
From 9/2000 to 7/2003: Northwest A&F University; M.S. in Veterinary Medicine
From 9/1987 to 7/1991: Yunnan Agricultural University; B.S. in Veterinary Medicine

   

From 1/2010 to present: Associate Professor, Kunming Institute of Botany, Chinese Academy of Sciences
From 3/2013 to 4/2014: Visiting Scholar, University of North Carolina at Chapel Hill, USA
From 10/2010 to 3/2011: Visiting Scholar, Okayama University, Japan
From 8/2006 to 12/2009: Assistant Professor, Kunming Institute of Botany, Chinese Academy of Sciences
From 8/1991 to 8/2000: Veterinarian, Bureau of Agriculture, Weixin County, Yunnan, China

   

[1] Wang Y. H. Naturally occurring polyhydroxylated spirostanol saponins, a review of the classification, sources, biosynthesis, biological activities, and toxicity. Chem. Biodivers., 2025, 22 (1), e202401720.

[2] Li S., Deng Y., Hu D.-B., Luo J.-F., Zhao P.-J., Yang J., Wang Y.-H. Chemical constituents, biological activities, and quality evaluation of agarwood produced from the qi-nan germplasm of Aquilaria sinensis. Phytochem. Lett., 2025, 65, 68-76.

[3] Duan X.-Y., Hu D.-B., Pandith H., Disayathanoowat T., Bai X., Yang J., Luo J.-F., Inta A., Wang Y.-H. Chemical constituents and antimicrobial properties of the nonresinous heartwood of Aquilaria sinensis. Chem. Nat. Compd., 2025, 61 (1), 42-51.

[4] Yang Y.-L., Bai X., Yang X.-Z., Luo J.-F., Duan X.-Y., Hu D.-B., Yang J., Wang Y.-H. Chemical constituents from the rhizomes of Paris xuefengshanensis. Fitoterapia, 2024, 179, 106257.

[5] Xia M., Munir S., Li Y., Ahmed A., He P., Wu Y., Li X., Tang P., Wang Z., He P., Wang Y., He Y. Bacillus subtilis YZ‐1 surfactins are involved in effective toxicity against agricultural pests. Pest Manag. Sci., 2024, 80 (2), 333-340.

[6] Li X., Nong X., Yang J., Li M., Wang Q., Sun M., Ma Q., Xu L., Wang Y. Exploring the frontier of cyclic dipeptides: A bioinformatics approach to potential therapeutic applications in schizophrenia. Int. J. Mol. Sci., 2024, 25 (21), 11421.

[7] Jia J.-K., Yang J., Yang X.-Z., Luo J.-F., Duan X.-Y., Yang Y.-L., Wan J.-F., Wang Y.-H. Cytotoxic steroidal glycosides from Paris rugosa rhizomes. Phytochem. Lett., 2024, 63, 1-7.

[8] Jia J.-K., Yang J., Yang X.-Z., Luo J.-F., Duan X.-Y., Yang Y.-L., Wan J.-F., Wang Y.-H. Polyhydroxylated spirostanol saponins from the rhizomes of Paris dulongensis. Chem. Biodivers., 2024, 21 (7), e202400980.

[9] Deng Y., Li S., Shi Y.-R., Hu D.-B., Luo J.-F., Zhao P.-J., Yuan W.-J., Wang Y.-H. Variation in the contents of four flavonoid glycosides in edible Dendrobium officinale leaves during different harvesting periods and optimization of the extraction process. Food Chem. X, 2024, 24, 101933.

[10] Chen X.-Y., Yang J., Yang X.-Z., Luo J.-F., Duan X.-Y., Hu D.-B., Wang Y.-H. Cytotoxicities of cucurbitacins from the stem bark of Aquilaria sinensis. Phytochem. Lett., 2024, 60, 190–193.

[11] Hu D.-B., Wei S.-Y., Yang J., Zhang D.-D., Duan X.-Y., Yan H., Yang X.-Z., Bai X., Luo J.-F., Yang J.-H., Wang Y.-S., Wang Y.-H. Heterodimers with a cucurbitane-type triterpenoid skeleton from the branches of Elaeocarpus dubius. Phytochemistry, 2023, 207, 113581.

[12] Chen Y.-F., Luo J.-F., Zhang Y.-N., Wang Y.-H. Tyrosinase inhibitory flavonoid diglycosides from Dendrobium officinale leaves. Chem. Nat. Compd., 2023, 59 (6), 1067–1074.

[13] Zhu X., Na X., Zeng Y., Xu Y., Chai D., Yang H., Miao J., Zhang Y., Yang F., Wang Y., Zhou Y. Polyphyllin I combined with doxorubicin shows chemosensitization effect in vivo and reduces immunotoxicity of doxorubicin. Mol. Cell. Toxicol., 2022, 18 (3), 359-369.

[14] Zhang L., Yi P., Yan H., Li X.-N., Xia M.-Y., Yang J., Luo J.-F., He Y.-Q., Wang Y.-H. Five new 2-(2-phenylethyl)chromone derivatives and three new sesquiterpenoids from the heartwood of Aquilaria sinensis, an aromatic medicine in China. Nat. Prod. Bioprospect., 2022, 12 (1), 2.

[15] Yang J., Hu D. B., Xia M. Y., Luo J. F., Li X. Y., Wang Y. H. Bioassay‑guided isolation of cytotoxic constituents from the flowers of Aquilaria sinensis. Nat. Prod. Bioprospect., 2022, 12 (1), 11.

[16] Xue Z., Zhang Y.-K., Yi P., Yang F.-M., Huo X.-M., Wang T.-T., Zhang H.-Y., Zhao B.-Y., Zeng Y.-R., Wang Y.-H., Tan C.-J. Ochrocephalamines E and F, two new alkaloids from Oxytropis ochrocephala Bung. Tetrahedron Lett., 2022, 102, 153943.

[17] Wang Y.-J., Yang J., Li X.-N., Bai H., Luo J.-F., He Z.-R., Wang Y.-H. Cucurbitane-type triterpenoids from the branches and leaves of Elaeocarpus sylvestris. Phytochem. Lett., 2022, 51, 39-45.

[18] Chen Y.-F., Zhang D.-D., Hu D.-B., Li X.-N., Luo J.-F., Duan X.-Y., Zhang Y.-N., Wang Y.-H. Alkaloids and flavonoids exert protective effects against UVB-induced damage in a 3D skin model using human keratinocytes. Results Chem., 2022, 4, 100298.

[1] Yang J, Wang Y, Luo J, Xia M, Zhang Y. Aquilaria sinensis extract useful in medicinal composition for preparing medicine for treating and preventing cancer, preferably lung cancer, cervical cancer, human neuroblastoma, ovarian cancer, leukemia, prostatic cancer and breast cancer. CN113262258-A.

[2] Wang Y, Zhang L, Luo J, Yang J. New white wood fragrant aquilarotetrol PES-22 is 1-(5-(1,2-dihydroxy-ethyl)-2,5-dihydro-furan-2-yl)-5-phenyl-pentane-1,3- diol compound, used for preparation of medicine for preventing and treating neurodegenerative diseases. CN113861135-A.

[3] Wang Y, Zhang D, Luo J, Li S. Use of Dendrobium officinale leaf total alkaloid PXS-115 in preparing cosmetic preservative, food preservative, antibacterial cosmetic and medicine, preparing medicine for treating skin aging, skin inflammation and skin cancer, preparing medicine or cosmetic for treating or preventing skin disease. CN113679653-A.

[4] Wang Y, Zhang D, Chen Y, Luo J, Hu D, Guo Y. Use of 1-(beta-carboline-1-yl)-3,4,5-trihydroxy-1-pentanone and/or 1-hydroxymethyl-beta-carboline for preparing anti-UVB radiation preparation, and anti-UVB radiation cosmetic, and medicine for treating and preventing skin aging caused by UVB radiation, skin inflammation and skin cancer. CN113616646-A.

[5] Wang Y, Weng Z, Lin H, Zhang X, Zhang Q, Li J, Liang L, Li X, He Q, Yang J, Luo J. Use of agilawood tetraol PFC24 in preparing medicine for preventing and treating vascular dementia disease. CN113694055-A.

[6] Wang Y, Chen Y, Luo J, Duan X, Wang Y. Use of vicenin-1 in preparing anti-UVB radiation medicine composition or/and cosmetic, improving activity of human epidermal keratinocytes after UVB irradiation, treating and preventing skin aging caused by UVB radiation, skin inflammation and skin cancer. CN113842383-A.

[7] Yang J, Wang Y, Luo J, Xia M, Li X, Hu D. Extracting cucurbitacin E, sakuranetin, and cucurbitacin B from ethyl acetate extraction part of Aquilaria sinensis extract comprises e.g. pulverizing and extracting dried flowers of Aquilaria sinensis, making extract into suspension and post-processing. CN113817013-A.

Ethnobotany

Medicinal chemistry

Natural products

Cardiovascular diseases

Nervous system diseases

Kunming Medical University

University of North Carolina at Chapel Hill

China Pharmaceutical University

Minzu University of China

Yunnan Agricultural University

Guizhou Medical University

已指导学生

柯镭喻  硕士研究生  085235-制药工程  

唐蓉  硕士研究生  078001-药物化学  

张璐  硕士研究生  085238-生物工程  

杨韬  硕士研究生  071001-植物学  

邱天雯  硕士研究生  071001-植物学  

杨莹莉  硕士研究生  071001-植物学  

陈小宇  硕士研究生  071001-植物学  

李海寅  硕士研究生  105500-药学  

贾建科  硕士研究生  105500-药学  

现指导学生

石梦雪  硕士研究生  071001-植物学