从事天然药物中痕量活性成分快速，高灵敏分析及中药功能提取物质量控制研究。

070302-分析化学
086000-生物与医药

药物分析化学，天然药物分析技术

2011-09--2015-12   兰州大学   博士学位
2008-09--2011-06   西北师范大学   获硕士学位
2004-09--2008-06   西北师范大学   获学士学位

   

2021-07~现在, 中国科学院兰州化学物理研究所, 副研究员
2016-04~2021-06,中国科学院兰州化学物理研究所, 助理研究员

[1] 杨军丽, 王伟峰, 张瑛. 毛细管电泳酶抑制剂精准筛选中草药活性分子的方法. CN: CN112114022A, 2020-12-22.

[2] 杨军丽, 孟宪华, 王伟峰. 一种具有抗高原缺氧功能的中药组合物. CN: CN110251550A, 2019-09-20.

[3] 杨军丽, 王伟峰, 师彦平. 一种检测鸟氨酸的比色分析方法. CN: CN106680270A, 2017-05-17.

[1] Wang, WeiFeng, Nsanzamahoro, Stanislas, Zhang, Ying, Wang, ChengBo, Shi, YanPing, Yang, JunLi. A highly sensitive colorimetric sensing platform based on silver nanocomposites for alkaline phosphatase. ANALYTICAL METHODS[J]. 2022, 14(24): 2431-2438, http://dx.doi.org/10.1039/d2ay00632d.
[2] Wang, Weifeng, Bi, Xiuru, Chai, Tian, Zhao, Peiqing, Yang, JunLi, Meng, Xu. Adsorption of Rutin from Aqueous Solution over an OMS-2-Modified ZrO2 Nanocomposite. CHEMISTRYSELECT[J]. 2022, 7(23): http://dx.doi.org/10.1002/slct.202200902.
[3] Zhang, Ying, Nsanzamahoro, Stanislas, Wang, ChengBo, Wang, WeiFeng, Yang, JunLi. Screening of prolyl hydroxylase 2 inhibitors based on quantitative strategy of peptides. JOURNAL OF CHROMATOGRAPHY A[J]. 2022, 1679: http://dx.doi.org/10.1016/j.chroma.2022.463411.
[4] Sun, Li, Wang, WeiFeng, Li, Mouji, Zhang, Jianbin, Chai, Tian, Cao, Wenhao, Yan, Tao, Zhao, Xiaoduo, Yang, Wufang, Yu, Bo, Huang, Guowei, Yang, JunLi, Zhou, Feng. Natural Product Zanthoxylum bungeanum Based Multi-Functionalized Self-Polishing Interface for Sustainable Marine Antifouling. ADVANCED MATERIALS INTERFACES[J]. 2022, 9(33): http://dx.doi.org/10.1002/admi.202201195.
[5] Li, CaiHong, Wang, WeiFeng, Stanislas, Nsanzamahoro, Yang, JunLi. Facile preparation of fluorescent water-soluble non-conjugated polymer dots and fabricating an acetylcholinesterase biosensor. RSC ADVANCES[J]. 2022, 12(13): 7911-7921, http://dx.doi.org/10.1039/d1ra07854b.
[6] Zhang, Ying, Zhao, Ming, Wang, ChengBo, Wang, Yu, Nsanzamahoro, Stanislas, Zhu, LingLing, Wang, WeiFeng, Yang, JunLi. Screening prolyl hydroxylase domain 2 inhibitory activity of traditional Chinese medicine by CZE-UV. ELECTROPHORESIS[J]. 2022, 43(15): 1601-1610, https://www.doi.org/10.1002/elps.202200028.
[7] Kong, Mengjuan, Jin, Peng, Wei, Wei, Wang, Weifeng, Qin, Hongyan, Chen, Hongli, He, Jiang. Covalent organic frameworks (COF-300-AR) with unique catalytic performance in luminol chemiluminescence for sensitive detection of serotonin. MICROCHEMICAL JOURNAL[J]. 2021, 160: http://dx.doi.org/10.1016/j.microc.2020.105650.
[8] Zhang, Ying, Zhong, HaiYang, Nsanzamahoro, Stanislas, Yao, XiaoJun, Wang, WeiFeng, Yang, JunLi. An online target and rapid screening method for alpha-glucosidase inhibitors based on capillary electrophoresis. ELECTROPHORESIS[J]. 2021, 42(11): 1221-1228, http://dx.doi.org/10.1002/elps.202000354.
[9] Stanislas Nsanzamahoro, WeiFeng Wang, Ying Zhang, ChengBo Wang, YanPing Shi, JunLi Yang. α‑Glucosidase-Triggered Reaction for Fluorometric and Colorimetric Assays Based on the Formation of Silicon-Containing Nanoparticles. Analytical Chemistry[J]. 2021, 93: 15412-15419, [10] Nsanzamahoro, Stanislas, Zhang, Ying, Wang, WeiFeng, Ding, YuZhu, Shi, YanPing, Yang, JunLi. Fluorescence "turn-on" of silicon-containing nanoparticles for the determination of resorcinol. MICROCHIMICA ACTA[J]. 2021, 188(2): 46-, https://www.webofscience.com/wos/woscc/full-record/WOS:000612848400001.
[11] Nsanzamahoro, Stanislas, Wang, WeiFeng, Zhang, Ying, Shi, YanPing, Yang, JunLi. Synthesis of orange-emissive silicon nanoparticles as "off-on" fluorescence probe for sensitive and selective detection of L-methionine and copper. TALANTA[J]. 2021, 231: 122369-, http://dx.doi.org/10.1016/j.talanta.2021.122369.
[12] Wang, Kai, Meng, XianHua, Chai, Tian, Wang, ChengBo, Sang, ChunYan, Wang, WeiFeng, Shang, XianYi, Yang, JunLi. Chemical constituents from the fruits of Zanthoxylum bungeanum and their chemotaxonomic significance. BIOCHEMICAL SYSTEMATICS AND ECOLOGY[J]. 2021, 99: http://dx.doi.org/10.1016/j.bse.2021.104356.
[13] Kong, Mengjuan, Wei, Wei, Wang, Weifeng, Chen, Hongli, He, Jiang. A novel metal organic gel with superior oxidase-like activity for efficient and sensitive chemiluminescence detection of uric acid. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY[J]. 2021, 257: http://dx.doi.org/10.1016/j.saa.2021.119773.
[14] Nsanzamahoro, Stanislas, Cheng, Wei, Mutuyimana, Felicite Pacifique, Li, Ling, Wang, Weifeng, Ren, Cuiling, Yi, Tao, Chen, Hongli, Chen, Xingguo. Target triggered fluorescence "turn-off" of silicon nanoparticles for cobalt detection and cell imaging with high sensitivity and selectivity. TALANTA[J]. 2020, 210: http://dx.doi.org/10.1016/j.talanta.2019.120636.
[15] WeiFeng Wang. 胶束电动毛细管电色谱法分析玫瑰纯露中的苯乙醇. 色谱. 2020, [16] Jin, Peng, Niu, Xiaoying, Zhang, Fang, Dong, Kui, Dai, Hongxia, Zhang, Huige, Wang, Weifeng, Chen, Hongli, Chen, Xingguo. Stable and Reusable Light-Responsive Reduced Covalent Organic Framework (COF-300-AR) as a Oxidase-Mimicking Catalyst for GSH Detection in Cell Lysate. ACS APPLIED MATERIALS & INTERFACES[J]. 2020, 12(18): 20414-20422, https://www.webofscience.com/wos/woscc/full-record/WOS:000535170300028.
[17] Ding, YuZhu, Wang, WeiFeng, Chai, Tian, Qiang, Yin, Shi, YanPing, Yang, JunLi. Ratiometric target-triggered fluorescent silicon nanoparticles probe for quantitative visualization of tyrosinase activity. TALANTA[J]. 2019, 197: 113-121, http://210.77.64.217/handle/362003/24922.
[18] Wang, WeiFeng, Yang, JunLi. Advances in screening enzyme inhibitors by capillary electrophoresis. ELECTROPHORESISnull. 2019, 40(16-17): 2075-2083, https://www.webofscience.com/wos/woscc/full-record/WOS:000478750500007.
[19] Wei, Nannan, Li, Ling, Zhang, Huige, Wang, Weifeng, Pan, Congjie, Qi, Shengda, Zhang, Hongyi, Chen, Hongli, Chen, Xingguo. Characterization of the Ligand Exchange Reactions on CdSe/ZnS QDs by Capillary Electrophoresis. LANGMUIR[J]. 2019, 35(14): 4806-4812, [20] Li, CaiHong, Meng, XianHua, Huong, Dang Lan, Oh, Won Keun, Wang, WeiFeng, Yang, JunLi. Quantitative visualization and detection of acetylcholinesterase activity and its inhibitor based on the oxidation character of ultrathin MnO2 nanosheets. ANALYTICAL METHODS[J]. 2019, 11(38): 4931-4938, [21] Wang, WeiFeng, Qiang, Yin, Meng, XianHua, Yang, JunLi, Shi, YanPing. Ultrasensitive colorimetric assay melamine based on in situ reduction to formation of CQDs-silver nanocomposite. SENSORS AND ACTUATORS B-CHEMICAL[J]. 2018, 260: 808-815, http://dx.doi.org/10.1016/j.snb.2018.01.108.
[22] 王君, 孟宪华, 王伟峰, 赵晓博, 李彩虹, 杨军丽, 师彦平. 抗AD活性天然化合物的结构与功能. 中国科学:化学[J]. 2018, 48(12): 1452-1465, http://lib.cqvip.com/Qikan/Article/Detail?id=6100232596.
[23] Qi, Xuan, Wang, WeiFeng, Wang, Jun, Yang, JunLi, Shi, YanPing. Highly selective colorimetric detection of putrescine in fish products using o-phthalaldehyde derivatization reaction. FOOD CHEMISTRY[J]. 2018, 259: 245-250, http://dx.doi.org/10.1016/j.foodchem.2018.03.131.
[24] Wang, WeiFeng, Qiang, Yin, Meng, XianHua, Yang, JunLi, Shi, YanPing. Ultrasensitive colorimetric assay melamine based on in situ reduction to formation of CQDs-silver nanocomposite. SENSORS AND ACTUATORS B-CHEMICAL[J]. 2018, 260: 808-815, http://dx.doi.org/10.1016/j.snb.2018.01.108.
[25] Wang, WeiFeng, Yang, JunLi, Shi, YanPing. Quality evaluation of six bioactive constituents in goji berry based on capillary electrophoresis field amplified sample stacking. ELECTROPHORESIS[J]. 2018, 39(16): 2117-2124, http://210.77.64.217/handle/362003/24657.
[26] Qiang, Yin, Wang, WeiFeng, Dhodary, Basanta, Yang, JunLi. Zeolitic imidazolate framework 8 (ZIF-8) reinforced macroporous resin D101 for selective solid-phase extraction of 1-naphthol and 2-naphthol from phenol compounds. ELECTROPHORESIS[J]. 2017, 38(13-14): 1685-1692, https://www.webofscience.com/wos/woscc/full-record/WOS:000406724100004.

   

（ 1 ） 用于高通量精准筛选百合中PDE4抑制剂的多内标-扫集毛细管电泳新方法, 主持, 国家级, 2018-01--2020-12
（ 2 ） 甘肃绞股蓝高原缺氧脑保护活性物质的分析、制备及功能产品, 主持, 省级, 2020-01--2022-12
（ 3 ） 靶向调节HIF-1信号通路的小分子化合物筛选鉴定及抗高原低氧脑损伤的天然药物的药效安全性评价, 主持, 研究所（学校）, 2020-11--2021-12
（ 4 ） 花椒籽、叶活性物质分析制备及在固液界面防护中的应用研究, 主持, 市地级, 2021-01--2022-12
（ 5 ） 枸杞抗阿尔茨海默病药物候选化合物研究, 主持, 省级, 2019-01--2021-12
（ 6 ） 抗高原缺氧功能营养剂研究, 主持, 部委级, 2022-01--2024-12