主要研究病毒感染机制与免疫干预手段，先后揭示MERS-CoV、SARS-CoV-2等冠状病毒受体识别机制及跨种传播机制，搭建抗原特异记忆B细胞筛选与单细胞测序平台，并成功获得多种病毒的高效人源中和抗体，为相关疾病的治疗提供了重要的候选药物。在Cell, Nature, Immunity, Science Translational Medicine（封面文章）等杂志发表研究论文100余篇，入选科睿唯安2022年度全球“高被引科学家”、爱思唯尔2023年度中国高被引学者；获批专利30余项，授权相关企业开发10项，其中新冠肺炎治疗性抗体曾获得美国等17个国家紧急使用授权，新冠多肽抑制剂完成II期临床试验；成果入选中国科学院“率先行动”计划第一阶段重大科技成果及标志性进展、2021年中国生命科学十大进展等。

   

100102-免疫学
071005-微生物学

传染病的mRNA疫苗开发
新型抗病毒药物设计与研发
长效疫苗研究与设计

2006-09--2012-01   中国科学院生物物理研究所   博士学位
2002-09--2006-07   哈尔滨工业大学   学士学位

   

2020-10~现在, 中国科学院微生物研究所, 研究员
2015-10~2020-10,中国科学院微生物研究所, 副研究员
2014-07~2015-09,中国科学院微生物研究所, 助理研究员
2012-02~2014-06,中国科学院微生物研究所, 博士后

2024-01-01-今,hLife, 编委
2023-07-01-今,北京医学会医学病毒学会分会, 第七届委员会委员
2023-05-31-今,北京技术市场协会, 第六届理事会理事
2023-01-01-今,中国科学：生命科学, 编委
2021-04-01-今,中国生物工程学会, 第七届理事会理事
2020-11-01-今,中国生物工程学会抗体工程专业委员会, 秘书长
2017-04-01-今,中国生物工程学会, 青年工作委员会委员

免疫治疗
分子病毒学

   

（1） 爱思唯尔2023中国高被引学者, , 其他, 2024
（2） 北京市先进科技工作者, , 省级, 2023
（3） 第十届“树兰医学青年奖”, 其他, 2023
（4） 科睿唯安2022年度全球“高被引科学家”, 其他, 2022
（5） 中国科学院青年创新促进会优秀会员, 部委级, 2022
（6） 第一届中国科学院青年五四奖章, 部委级, 2022
（7） 2021年中国生命科学十大进展, 部委级, 2022
（8） 全国科技系统抗击新冠肺炎疫情先进个人, , 部委级, 2021
（9） 中国科学院青年科学家奖, 部委级, 2021
（10） 北京朝阳区2021凤凰计划青年拔尖人才, 省级, 2021
（11） 第十四届吴孟超医学青年基金奖, 部委级, 2021
（12） 第十四届谈家桢生命科学创新奖, 部委级, 2021
（13） 抗击新冠肺炎疫情全国三八红旗集体奖, , 部委级, 2020
（14） 中源协和生命医学创新突破奖, 其他, 2017

（ 1 ） 一种抗新型冠状病毒的多肽及其应用, 发明专利, 2022, 第 2 作者, 专利号: ZL202110939740.1

（ 2 ） 纳米抗体R14的构建体及其应用, 发明专利, 2022, 第 1 作者, 专利号: ZL202210375857.6

（ 3 ） 黄病毒抗体及其应用, 发明专利, 2021, 第 5 作者, 专利号: CN113683691A

（ 4 ） 针对黄热病毒NS1蛋白的抗体及其应用, 发明专利, 2021, 第 5 作者, 专利号: CN113683690A

（ 5 ） 黄热病毒抗体及其应用, 发明专利, 2021, 第 5 作者, 专利号: CN113621058A

（ 6 ） 与新型冠状病毒的抗体有效结合的表位, 发明专利, 2021, 第 3 作者, 专利号: CN113527444A

（ 7 ） 新型冠状病毒的人源单克隆抗体及其应用, 发明专利, 2021, 第 3 作者, 专利号: CN113444169A

（ 8 ） 冠状病毒的人源单克隆抗体及其应用, 发明专利, 2021, 第 3 作者, 专利号: CN113354731A

（ 9 ） 针对新型冠状病毒的人ACE2改造蛋白、ACE2-hFc类抗体蛋白, 发明专利, 2021, 第 2 作者, 专利号: CN112794918A

（ 10 ） 一种寨卡/登革疫苗及其应用, 发明专利, 2021, 第 6 作者, 专利号: CN112194712A

（ 11 ） 一种裂谷热病毒人源单克隆抗体及其应用, 发明专利, 2020, 第 2 作者, 专利号: CN109734800B

（ 12 ） 一种高中和活性的寨卡病毒人源单克隆抗体及其应用, 专利授权, 2019, 第 3 作者, 专利号: CN110172095A

（ 13 ） 一种寨卡病毒特异性中和抗体及其应用, 专利授权, 2019, 第 3 作者, 专利号: CN110066333A

（ 14 ） 一种裂谷热病毒人源单克隆抗体及其应用, 专利授权, 2019, 第 2 作者, 专利号: CN109734800A

（ 15 ） 一种黄病毒人源单克隆抗体及应用, 专利授权, 2017, 第 1 作者, 专利号: CN106589116A

（ 16 ） 一种寨卡病毒人源单克隆抗体及其应用, 专利授权, 2017, 第 3 作者, 专利号: CN106279409A

   

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（1） 中东呼吸综合征公众防护问答, 科学普及出版社, 2015-01, 第 其他 作者
（2） 寨卡病毒与寨卡病毒病, 人民卫生出版社, 2019-05, 第 其他 作者
（3） 时不我待：追踪致命病毒的精彩人生, No time to loose: a life in pursuit of deadly viruses, 中国科学技术出版社, 2021-01, 第 1 作者
（4） 《流感病毒：躲也躲不过的敌人》有声书, Influenza Virus, 喜马拉雅, 2023-11, 第 1 作者

   

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