发表论文
[1] Dron, Jacqueline S, Patel, Aniruddh P, Zhang, Yiyi, Jurgens, Sean J, Maamari, Dimitri J, Wang, Minxian, Boerwinkle, Eric, Morrison, Alanna C, de Vries, Paul S, Fornage, Myriam, Hou, Lifang, LloydJones, Donald M, Psaty, Bruce M, Tracy, Russell P, Bis, Joshua C, Vasan, Ramachandran S, Levy, Daniel, HeardCosta, Nancy, Rich, Stephen S, Guo, Xiuqing, Taylor, Kent D, Gibbs, Richard A, Rotter, Jerome I, Willer, Cristen J, Oelsner, Elizabeth C, Moran, Andrew E, Peloso, Gina M, Natarajan, Pradeep, Khera, Amit V. Association of Rare Protein-Truncating DNA Variants in APOB or PCSK9 With Low-density Lipoprotein Cholesterol Level and Risk of Coronary Heart Disease. JAMA CARDIOLOGY. 2023, 第 6 作者http://dx.doi.org/10.1001/jamacardio.2022.5271.[2] Patel, Aniruddh P, Wang, Minxian, Ruan, Yunfeng, Koyama, Satoshi, Clarke, Shoa L, Yang, Xiong, Tcheandjieu, Catherine, Agrawal, Saaket, Fahed, Akl C, Ellinor, Patrick T, Tsao, Philip, Sun, Yan, V, Cho, Kelly, Wilson, Peter W F L, Assimes, Themistocles L, van Heel, David A, Butterworth, Adam S, Aragam, Krishna G, Natarajan, Pradeep, Khera, Amit V, Genes Hlth Res Team, Million Vet Program. A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease. NATURE MEDICINE[J]. 2023, 第 11 作者29(7): 1793-+, http://dx.doi.org/10.1038/s41591-023-02429-x.[3] Chun, Justin, Riella, Cristian, V, Chung, Hyunjae, Shah, Shrijal S, Wang, Minxian, Magraner, Jose M, Ribas, Guilherme T, Ribas, Hennrique T, Zhang, JiaYue, Alper, Seth L, Friedman, David J, Pollak, Martin R. DGAT2 Inhibition Potentiates Lipid Droplet Formation To Reduce Cytotoxicity in APOL1 Kidney Risk Variants. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY[J]. 2022, 第 5 作者33(5): 889-907, [4] Biddinger, Kiran J, Emdin, Connor A, Haas, Mary E, Wang, Minxian, Hindy, George, Ellinor, Patrick T, Kathiresan, Sekar, Khera, Amit, V, Aragam, Krishna G. Association of Habitual Alcohol Intake With Risk of Cardiovascular Disease. JAMA NETWORK OPEN[J]. 2022, 第 4 作者5(3): http://dx.doi.org/10.1001/jamanetworkopen.2022.3849.[5] Fahed, Akl C, Wang, Minxian, Patel, Aniruddh P, Ajufo, Ezimamaka, Maamari, Dimitri J, Aragam, Krishna G, Brockman, Deanna G, Vosburg, Trish, Ellinor, Patrick T, Ng, Kenney, Khera, Amit, V. Association of the Interaction Between Familial Hypercholesterolemia Variants and Adherence to a Healthy Lifestyle With Risk of Coronary Artery Disease. JAMA NETWORK OPEN[J]. 2022, 第 2 作者5(3): http://dx.doi.org/10.1001/jamanetworkopen.2022.2687.[6] Khera, Amit, V, Wang, Minxian, Chaffin, Mark, Emdin, Connor A, Samani, Nilesh J, Schunkert, Heribert, Watkins, Hugh, McPherson, Ruth, Erdmann, Jeanette, Elosua, Roberto, Boerwinkle, Eric, Ardissino, Diego, Butterworth, Adam S, Di Angelantonio, Emanuele, Naheed, Aliya, Danesh, John, Chowdhury, Rajiv, Krumholz, Harlan M, Sheu, Wayne HH, Rich, Stephen S, Rotter, Jerome, I, Chen, Yiider Ida, Gabriel, Stacey, Lander, Eric S, Saleheen, Danish, Kathiresan, Sekar. Gene Sequencing Identifies Perturbation in Nitric Oxide Signaling as a Nonlipid Molecular Subtype of Coronary Artery Disease. CIRCULATION-GENOMIC AND PRECISION MEDICINE[J]. 2022, 第 2 作者15(6): 551-559, [7] Patel, Aniruddh P, Dron, Jacqueline S, Wang, Minxian, Pirruccello, James P, Ng, Kenney, Natarajan, Pradeep, Lebo, Matthew, Ellinor, Patrick T, Aragam, Krishna G, Khera, Amit, V. Association of Pathogenic DNA Variants Predisposing to Cardiomyopathy With Cardiovascular Disease Outcomes and All-Cause Mortality. JAMA CARDIOLOGY[J]. 2022, 第 3 作者7(7): 723-732, http://dx.doi.org/10.1001/jamacardio.2022.0901.[8] Milosavljevic, Julian, Lempicki, Camille, Lang, Konrad, Heinkele, Helena, Kampf, Lina L, Leroy, Claire, Chen, Mengmeng, Gerstner, Lea, Spitz, Dominik, Wang, Minxian, Knob, Andrea U, Kayser, Severine, Helmstadter, Martin, Walz, Gerd, Pollak, Martin R, Hermle, Tobias. Nephrotic Syndrome Gene TBC1D8B Is Required for Endosomal Maturation and Nephrin Endocytosis in Drosophila. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY[J]. 2022, 第 10 作者33(12): 2174-2193, http://dx.doi.org/10.1681/ASN.2022030275.[9] Saaket Agrawal, Minxian Wang, Marcus D R Klarqvist, Kirk Smith, Joseph Shin, Hesam Dashti, Nathaniel Diamant, Seung Hoan Choi, Sean J Jurgens, Patrick T Ellinor, Anthony Philippakis, Melina Claussnitzer, Kenney Ng, Miriam S Udler, Puneet Batra, Amit V Khera. Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots. NATURE COMMUNICATIONS[J]. 2022, 第 2 作者13(1): 1-17, https://doaj.org/article/708f44bb6b094581a53300838b54ced3.[10] Peng, Lihong, Yang, Jialiang, Wang, Minxian, Zhou, Liqian. Editorial: Machine Learning-Based Methods for RNA Data Analysis. FRONTIERS IN GENETICS[J]. 2022, 第 3 作者13: http://dx.doi.org/10.3389/fgene.2022.828575.[11] Dron, Jacqueline S, Wang, Minxian, Patel, Aniruddh P, Kartoun, Uri, Ng, Kenney, Hegele, Robert A, Khera, Amit V. Genetic Predictor to Identify Individuals With High Lipoprotein(a) Concentrations. CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2021, 第 2 作者14(1): http://dx.doi.org/10.1161/CIRCGEN.120.003182.[12] Wang, Minxian, LeeKim, Vivian S, Atri, Deepak S, Elowe, Nadine H, Yu, John, Garvie, Colin W, Won, HongHee, Hadaya, Joseph E, MacDonald, Bryan T, Trindade, Kevin, Melander, Olle, Rader, Daniel J, Natarajan, Pradeep, Kathiresan, Sekar, Kaushik, Virendar K, Khera, Amit V, Gupta, Rajat M. Rare, Damaging DNA Variants in CORIN and Risk of Coronary Artery Disease Insights From Functional Genomics and Large-Scale Sequencing Analyses. CIRCULATION-GENOMIC AND PRECISION MEDICINE[J]. 2021, 第 1 作者14(5): http://dx.doi.org/10.1161/CIRCGEN.121.003399.[13] Weng, Patricia L, Majmundar, Amar J, Khan, Kamal, Lim, Tze Y, Shril, Shirlee, Jin, Gina, Musgrove, John, Wang, Minxian, Ahram, Dina F, Aggarwal, Vimla S, Bier, Louise E, Heinzen, Erin L, OnuchicWhitford, Ana C, Mann, Nina, Buerger, Florian, Schneider, Ronen, Deutsch, Konstantin, Kitzler, Thomas M, Klambt, Verena, Kolb, Amy, Mao, Youying, El Achkar, Christelle Moufawad, Mitrotti, Adele, Martino, Jeremiah, Beck, Bodo B, Altmuller, Janine, Benz, Marcus R, Yano, Shoji, Mikati, Mohamad A, Gunduz, Talha, Cope, Heidi, Shashi, Vandana, Trachtman, Howard, Bodria, Monica, Caridi, Gianluca, Pisani, Isabella, Fiaccadori, Enrico, AbuMaziad, Asmaa S, MartinezAgosto, Julian A, Yadin, Ora, Zuckerman, Jonathan, Kim, Arang, JohnKroegel, Ulrike, Tyndall, Amanda, V, Parboosingh, Jillian S, Innes, A Micheil, Bierzynska, Agnieszka, Koziell, Ania B, Muorah, Mordi, Saleem, Moin A, Hoefele, Julia, Riedhammer, Korbinian M, Gharavi, Ali G, Jobanputra, Vaidehi, PierceHoffman, Emma, Seaby, Eleanor G, ODonnellLuria, Anne, Rehm, Heidi L, Mane, Shrikant, DAgati, Vivette D, Pollak, Martin R, Ghiggeri, Gian Marco, Lifton, Richard P, Goldstein, David B, Davis, Erica E, Hildebrandt, Friedhelm, SannaCherchi, Simone, Undiagnosed Dis Network, UCLA Clinical Genomics Ctr. De novo TRIM8 variants impair its protein localization to nuclear bodies and cause developmental delay, epilepsy, and focal segmental glomerulosclerosis. AMERICAN JOURNAL OF HUMAN GENETICS[J]. 2021, 第 8 作者108(2): 357-367, http://dx.doi.org/10.1016/j.ajhg.2021.01.008.[14] Cai, Yudong, Yang, Jialiang, Huang, Tao, Wang, Minxian Wallace. Editorial: Computational Methods in Predicting Complex Disease Associated Genes and Environmental Factors. FRONTIERS IN GENETICS[J]. 2021, 12: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097088/.[15] Fahed, Akl C, Wang, Minxian, Homburger, Julian R, Patel, Aniruddh P, Bick, Alexander G, Neben, Cynthia L, Lai, Carmen, Brockman, Deanna, Philippakis, Anthony, Ellinor, Patrick T, Cassa, Christopher A, Lebo, Matthew, Ng, Kenney, Lander, Eric S, Zhou, Alicia Y, Kathiresan, Sekar, Khera, Amit V. Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions. NATURE COMMUNICATIONS[J]. 2020, 第 2 作者11(1): http://dx.doi.org/10.1038/s41467-020-17374-3.[16] Chun, Justin, Wang, Minxian, Wilkins, Maris S, Knob, Andrea U, Benjamin, Ave, Bu, Lihong, Pollak, Martin R. Autosomal Dominant Tubulointerstitial Kidney Disease-Uromodulin Misclassified as Focal Segmental Glomerulosclerosis or Hereditary Glomerular Disease. KIDNEY INTERNATIONAL REPORTS[J]. 2020, 第 2 作者5(4): 519-529, http://dx.doi.org/10.1016/j.ekir.2019.12.016.[17] Emdin, Connor A, Bhatnagar, Pallav, Wang, Minxian, Pillai, Sreekumar G, Li, Lin, Qian, HuiRong, Riesmeyer, Jeffrey S, Lincoff, A Michael, Nicholls, Stephen J, Nissen, Steven E, Ruotolo, Giacomo, Kathiresan, Sekar, Khera, Amit V. Genome-Wide Polygenic Score and Cardiovascular Outcomes With Evacetrapib in Patients With High-Risk Vascular Disease A Nested Case-Control Study. CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2020, 第 3 作者13(1): e002767-e002767, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031044/.[18] Patel, Aniruddh P, Wang, Minxian, Fahed, Akl C, MasonSuares, Heather, Brockman, Deanna, Pelletier, Renee, Amr, Sami, Machini, Kalotina, Hawley, Megan, Witkowski, Leora, Koch, Christopher, Philippakis, Anthony, Cassa, Christopher A, Ellinor, Patrick T, Kathiresan, Sekar, Ng, Kenney, Lebo, Matthew, Khera, Amit, V. Association of Rare Pathogenic DNA Variants for Familial Hypercholesterolemia, Hereditary Breast and Ovarian Cancer Syndrome, and Lynch Syndrome With Disease Risk in Adults According to Family History. JAMA NETWORK OPEN[J]. 2020, 第 2 作者3(4): e203959-e203959, http://dx.doi.org/10.1001/jamanetworkopen.2020.3959.[19] Wang Minxian. Lp(a) (Lipoprotein [a]) Concentrations and Incident Atherosclerotic Cardiovascular Disease. Arteri osclerosis, Thrombosis, and Vascular Biology. 2020, 第 1 作者[20] Pirruccello, James P, Bick, Alexander, Wang, Minxian, Chaffin, Mark, Friedman, Samuel, Yao, Jie, Guo, Xiuqing, Venkatesh, Bharath Ambale, Taylor, Kent D, Post, Wendy S, Rich, Stephen, Lima, Joao A C, Rotter, Jerome I, Philippakis, Anthony, Lubitz, Steven A, Ellinor, Patrick T, Khera, Amit V, Kathiresan, Sekar, Aragam, Krishna G. Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy. NATURE COMMUNICATIONS[J]. 2020, 第 3 作者11(1): [21] Wang, Minxian, Menon, Ramesh, Mishra, Sanghamitra, Patel, Aniruddh P, Chaffin, Mark, Tanneeru, Deepak, Deshmukh, Manjari, Mathew, Oshin, Apte, Sanika, Devanboo, Christina S, Sundaram, Sumathi, Lakshmipathy, Praveena, Murugan, Sakthivel, Sharma, Krishna Kumar, Rajendran, Karthikeyan, Santhosh, Sam, Thachathodiyl, Rajesh, Ahamed, Hisham, Balegadde, Aniketh Vijay, Alexander, Thomas, Swaminathan, Krishnan, Gupta, Rajeev, Mullasari, Ajit S, Sigamani, Alben, Kanchi, Muralidhar, Peterson, Andrew S, Butterworth, Adam S, Danesh, John, Di Angelantonio, Emanuele, Naheed, Aliya, Inouye, Michael, Chowdhury, Rajiv, Vedam, Ramprasad L, Kathiresan, Sekar, Gupta, Ravi, Khera, Amit V. Validation of a Genome-Wide Polygenic Score for Coronary Artery Disease in South Asians. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY[J]. 2020, 第 1 作者76(6): 703-714, http://dx.doi.org/10.1016/j.jacc.2020.06.024.[22] Feng, Di, Kumar, Mukesh, Muntel, Jan, Gurley, Susan B, Birrane, Gabriel, Stillman, Isaac E, Ding, Lai, Wang, Minxian, Ahmed, Saima, Schlondorff, Johannes, Alper, Seth L, Ferrante, Tom, Marquez, Susan L, Ng, Carlos F, Novak, Richard, Ingber, Donald E, Steen, Hanno, Pollak, Martin R. Phosphorylation of ACTN4 Leads to Podocyte Vulnerability and Proteinuric Glomerulosclerosis. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY[J]. 2020, 第 8 作者31(7): 1479-1495, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351002/.[23] Wang, Minxian, Chun, Justin, Genovese, Giulio, Knob, Andrea U, Benjamin, Ava, Wilkins, Maris S, Friedman, David J, Appel, Gerald B, Lifton, Richard P, Mane, Shrikant, Pollak, Martin R. Contributions of Rare Gene Variants to Familial and Sporadic FSGS. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY[J]. 2019, 第 1 作者30(9): 1625-1640, http://dx.doi.org/10.1681/ASN.2019020152.[24] Riella, Cristian, Siemens, Tobias A, Wang, Minxian, Campos, Rodrigo P, Moraes, Thyago P, Riella, Leonardo, V, Friedman, David J, Riella, Miguel C, Pollak, Martin R. APOL1-Associated Kidney Disease in Brazil. KIDNEY INTERNATIONAL REPORTS[J]. 2019, 第 3 作者4(7): 923-929, http://dx.doi.org/10.1016/j.ekir.2019.03.006.[25] Khetarpal, Sumeet A, Wang, Minxian, Khera, Amit V. Volanesorsen, Familial Chylomicronemia Syndrome, and Thrombocytopenia. NEW ENGLAND JOURNAL OF MEDICINE. 2019, 第 2 作者381(26): 2582-2584, http://dx.doi.org/10.1056/NEJMc1912350.[26] Khera, Amit V, MasonSuares, Heather, Brockman, Deanna, Wang, Minxian, VanDenburgh, Martin J, SenolCosar, Ozlem, Patterson, Candace, NewtonCheh, Christopher, Zekavat, Seyedeh M, Pester, Julie, Chasman, Daniel I, Kabrhel, Christopher, Jensen, Majken K, Manson, JoAnn E, Gaziano, J Michael, Taylor, Kent D, Sotoodehnia, Nona, Post, Wendy S, Rich, Stephen S, Rotter, Jerome I, Lander, Eric S, Rehm, Heidi L, Ng, Kenney, Philippakis, Anthony, Lebo, Matthew, Albert, Christine M, Kathiresan, Sekar. Rare Genetic Variants Associated With Sudden Cardiac Death in Adults. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY[J]. 2019, 第 4 作者74(21): 2623-2634, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067308/.[27] Feng, Di, Notbohm, Jacob, Benjamin, Ava, He, Shijie, Wang, Minxian, Ang, LayHong, Bantawa, Minaspi, Bouzid, Mehdi, Del Gado, Emanuela, Krishnan, Ramaswamy, Pollak, Martin R. Disease-causing mutation in alpha-actinin-4 promotes podocyte detachment through maladaptation to periodic stretch. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2018, 第 5 作者115(7): 1517-1522, https://www.webofscience.com/wos/woscc/full-record/WOS:000424876000069.[28] Zhang, JiaYue, Wang, Minxian, Tian, Lei, Genovese, Giulio, Yan, Paul, Wilson, James G, Thadhani, Ravi, Mottl, Amy K, Appel, Gerald B, Bick, Alexander G, Sampson, Matthew G, Alper, Seth L, Friedman, David J, Pollak, Martin R. UBD modifies APOL1-induced kidney disease risk. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2018, 第 2 作者 通讯作者 115(13): 3446-3451, http://dx.doi.org/10.1073/pnas.1716113115.[29] Zhou, Bin, Dong, Hui, He, Yungang, Sun, Jian, Jin, Weirong, Xie, Qing, Fan, Rong, Wang, Minxian, Li, Ran, Chen, Yangyi, Xie, Shaoqing, Shen, Yan, Huang, Xin, Wang, Shengyue, Lu, Fengming, Jia, Jidong, Zhuang, Hui, Locarnini, Stephen, Zhao, GuoPing, Jin, Li, Hou, Jinlin. Composition and Interactions of Hepatitis B Virus Quasispecies Defined the Virological Response During Telbivudine Therapy. SCIENTIFIC REPORTS[J]. 2015, 第 8 作者5: https://www.webofscience.com/wos/woscc/full-record/WOS:000365198100002.[30] He, Yungang, Wang, Minxian, Huang, Xin, Li, Ran, Xu, Hongyang, Xu, Shuhua, Jin, Li. A probabilistic method for testing and estimating selection differences between populations. GENOME RESEARCH[J]. 2015, 第 2 作者25(12): 1903-1909, http://dx.doi.org/10.1101/gr.192336.115.[31] Wang, Minxian, Huang, Xin, Li, Ran, Xu, Hongyang, Jin, Li, He, Yungang. Detecting Recent Positive Selection with High Accuracy and Reliability by Conditional Coalescent Tree. MOLECULAR BIOLOGY AND EVOLUTION[J]. 2014, 第 1 作者31(11): 3068-3080, http://dx.doi.org/10.1093/molbev/msu244.[32] Jiang, Yueming, Wang, Minxian, Zheng, Hongxiang, Wang, Wei R, Jin, Li, He, Yungang. Resolving ambiguity in the phylogenetic relationship of genotypes A, B, and C of hepatitis B virus. BMC EVOLUTIONARY BIOLOGY[J]. 2013, 第 2 作者13(1): 120-120, http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201706294211428ZK.[33] Li, Ran, Wang, Minxian, Jin, Li, He, Yungang. A Monte Carlo Permutation Test for Random Mating Using Genome Sequences. PLOS ONE[J]. 2013, 第 2 作者8(8): https://doaj.org/article/fa8cc36f7d3e49d598712f50bd9dafa9.