Synthetic Biology and Metabolic Engineering

Ph.D.  Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences

B.S.  Shandong University

Professor, Institute of Synthetic Biology, SIAT, CAS, 2019-date

Postdoctoral Research Associate, Chalmers, 2015-2019

   

[1]Yu T*, Dabirian Y*, Liu Q, Siewers V, Nielsen J. (2019) Strategies and Challenges for Metabolic Rewiring. Current Opinion in Systems Biology 15:30-38(*co-first author)

[2]Liu, Q.,Yu, T.,Li, X.,Chen, Y.,Campbell, K.,Nielsen, J.,Chen, Y. (2019) Rewiring carbon metabolism in yeast for high level production of aromatic chemicals. Nature Communications 10:4976

[3]Yu T*, Zhou Y .J.J*, Huang M, Liu Q, Pereira R, David F, Nielsen J. (2018) Reprogramming Yeast Metabolism from Alcoholic Fermentation to Lipogenesis. Cell 174(6):1549-1558 (*co-first author)

[4]Yu, T., Zhou, Y.J.J., Wenning, L., Liu, Q.L., Krivoruchko, A., Siewers, V., Nielsen, J., and David, F. (2017) Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals. Nature Communications 8:15587

[5]Wenning, L.,Yu, T.,David, F,Nielsen, J.,Siewers,V(2017)Establishing Very Long-Chain Fatty Alcohol and Wax Ester Biosynthesis in Saccharomyces cerevisiae. Biotechnology and Bioengineering 114:1025–1035

[6]Yu, T., Tao, Y., Yang, M., Chen, P., Gao, X., Zhang, Y., Zhang, T., Chen, Z., Hou, J., Zhang, Y.,Ruan,K., Wang,H., Hu,R.G.* (2014)  Profiling human protein degradome delineates cellular responses to proteasomal inhibition and reveals a feedback mechanism in regulating proteasome homeostasis. Cell Research 24:1214-1230