My research interest is focused on the industrial, agricultural and applied microbiolgy, which mainly includes the comprohesive studies of the industrial microbes, metabolic products, enzymes and other functional microbial materials. Current studies are focusing on the analysis of the fundamental processes of microbes in biosynthesis, metabolism and iltrnsformation of relevant compuunds, and the development of novel processes and products for industrial application. In addition,  my research interest is also in developing statistically sound and computationally ecient methods to address important biological problems in genetics and genomics. These problems often involve large-scale and high-dimensional "big data", which come from, for example, genome-wide association studies and functional genomics studies. Through developing novel statistical methods and analytic tools, I hope to advance our understanding of the genetic basis of phenotypic variation.

Russian State Agrarian University-MTTA named after K.A.Timiryazev: Moscow, Russia

• Ph.D., 06/2009

St.Petersburg State University: St.Petersburg, Russia

• M.S., 09/2004

St.Petersburg State Agriculture University: St.Petersburg , Russia

• B.S., 09/2002

Institute of Modern Physics, Chinese Academy of Sciences

•Departments of Biophysics/Drug R & D Center, 11/2013 - present

•Postdoctoral Scholar, Departments of Biophysics/Drug R & D Center, 10/2010 - 11/2013

 • American Chemical Society, Membership. 2016

 • ACS, Chemistry for Life^@, Membership. 2016

 • SCI Membership. 2016

 • CAS Light of West China talent training Program-“Western Scholars”. 2015

 • K.C.Wong Education Foundation of Talent Award. 2013

 • China Postdoctoral Science Foundation, once of second prize. 2011

• Zhou Xiang*, Xu Dan, Jiang Ting-Ting, Simplifying multidimensional fermentation dataset analysis and visualization: One step closer to capturing high-quality mutant strains, Scientific Reports, 2016, 9, 39875.

• Zhou Xiang*, Yang Zhen, Jiang Ting-Ting, Wang Shu-Yang, Liang Jian-Ping, Lu Xi-Hong, Wang Liang. The acquisition of Clostridium tyrobutyricum mutants with improved bioproduction under acidic conditions after two rounds of heavy-ion beam irradiation, Scientific Reports, 2016,6: 29968.

• Zhou Xiang, Wang Shu-Yang, Lu Xi-Hong, Liang Jian-Ping.Comparison of the effects of high energy carbon heavy ion irradiation and Eucommia ulmoides Oliv. on biosynthesis butyric acid efficiency in Clostridium tyrobutyricum ,Bioresource Technology, 2014,161(1): 221-229.

• Zhou Xiang*，Lu Xi-Hong, Li Xue-Hu, Xin  Zhi-Jun, Xie Jia-Rong, Zhao  Mei-Rong, Wang Liang, Du Wen-Yue, Liang Jian-Ping. Radiation induces acid tolerance of Clostridium tyrobutyricum and enhances bioproduction of butyric acid through a metabolic switch.，Biotechnology for Biofuels，2014, 7(1):(22).

• Zhou Xiang*，Xie  Jia-Rong, Tao Lei, Xin Zhi-Jun, Zhao  Feng-Wu, Lu, Xi-Hong, Zhao Mei-Rong, Wang  Liang, Liang Jian-Ping. The effect of microdosimetric 12C6+ heavy ion irradiation and Mg2+ on canthaxanthin production in a novel strain of Dietzia natronolimnaea，BMC Microbiology，2013, 13 (1): 213-213.

• Zhou Xiang，Xin, Zhi-Jun, Lu Xi-Hong, Yang  Xian-Peng, Zhao  Mei-Rong, Wang Liang, Liang Jian-Ping. High efficiency degradation crude oil by a novel mutant irradiated from Dietzia strain by 12C6+ heavy ion using response surface methodology, Bioresource Technology，2013,137: 386-393.

• Zhou Xiang, Liang Jianping, Li Xuehu, Lu Xihong, Guo Zhiting, Hao Baocheng. Dietzia maris Induced by Carbon-ion Beams and Its Biodegradation Ability, Science & Technology Review, 2012, 30(12):21-25.

• Zhou Xiang* ,Liang Jianping, Li Xuehu, Lu Xihong, Strain Improvements of Aspergillus niger and Trichoderma viride for Increased Cellulase Production by Irradiation of Electron and 12C6+-ion Beams，Annual Report，2011，20（10）:200-202.

• Zhou Xiang*, Liang Jianping, Lu Xihong, Anti-porcine Respiratory and Reproductive Syndrome Virus Effects of Extract from Isatis Indigotica Fortune，Annual Report，2012，17（9）:116-119.

• Zhou Xiang, Liang Jian-Ping, Ran Mao-Sheng, Lu, Xi-Hong, Li Xue-Hu, Wang Shu-Yang. Dietzia maris bacterial susceptibllity analysis identified Ьу VapA/VapB genotype, Journal of Lanzhou University, 2012, 38(2): 10-14.

• Zhou Xiang, Liang Jian-Ping, Xin Zhi-Jun, Lu Xi-Hong, Yang Xian-Peng, Guo Zhi-Ting, Hao Bao-Cheng. Research on Dietzia Maris Strain Induced by Carbon-Ion Beams and Its Bioremediation of Diesel Oil Contaminated Soil, Journal of Nuclear Agricultural Sciences, 2013, 27(6): 0823-0830.

• Zhou Xiang, Xie Jiarong, Liang Jianping, Xin Zhijun, Lu Xihong, Guo Zhiting, Hao Baocheng, Yang Xianpeng, Zhao Meirong, WangLiang, Degradation crude oil by 12C6 + ion irradiated from Dietzia strain using response surface methodology, Acta Scientiae Circumstantiae, 2013, 33(9):2473-2481.

• Zhou Xiang*, Jiang, Ting-Ting, Xu Dan. Combining Logistic Regression and Markov Chain Monte-Carlo describe the relationship between exposure to a given dose of radiation and its effect on Clostridium acetobutylicum strains, Nuclear Physics Review, 2016.5,234-241.

• Jiang, Ting-Ting, Zhou Xiang*, Liang Yan. A small-scale investigation process for the Clostridium acetobutylicum production of butanol using high-energy carbon heavy ion irradiation, Engineering in Life Sciences, 2018.18,231-247.

• Jiang, Ting-Ting, Zhou Xiang*, Liang Yan, Jiang Ai-Lian, Liang Jian-Ping, Effects of Different Stem Skin and Marrow Root Mesh Sizes in Sweet Sorghum Bagasse on the Release of Sugar in Hydrolysis, Sugar Tech, 2018.10,121-137.

• Tao Lei, Liang Yan, Zhou Xiang, et al., Effect of Using Carbon-ion Beam Irradiation on Sustained-release Characteristic and Anti-coccidial Activity of Oregano Essential Oil Microcapsules, Nuclear Physics Review, 2018.35,181-188.

• Du Wenyue, Lu Xihong, Li Xuehu, Zhou Xiang, Breeding pleuromutilin protoplasts strains by carbon ion beam irradiation, J. Radiat. Res. Radiat. Process., 2016, 34,39-44.

•Wang Shu-Yang, Bo Yong-Heng, Xiang Zhou#, Chen Ji-Hong, Li Wen-Jian, Liang Jian-Ping, Xiao Guo-Qing, Wang Yu-Chen, Liu Jing, Hu Wei, Jiang Bo-Ling，Significance of heavy-ion beam irradiation-induced avermectin B1a production by engineered Streptomyces avermitilis，BioMed Research International，2016.

• Wang Shu-Yang，Jiang Bo-Ling，Zhou Xiang# ，Chen Ji-Hong，Li Wen-Jian，Liu Jing，Hu Wei，Xiao Guo-Qing，Dong Miao-Yin，Wang Yu-Chen，Study of a High-Yield Cellulase System Created by Heavy-Ion Irradiation-Induced Mutagenesis of Aspergillus niger and Mixed Fermentation with Trichodermareesei，PLoS One，2015，10（12）.

• Guo Zhi-Ting, Zhou Xiang*, Wang Hua-Dong, Liang Jian-Ping, Guo Wen-Zhu, Xiong Lin, Identification of Radix Dichroae and fake Chinese Mahonia, Journal of Traditional Chinese Veterinary Medicine, 2014,23(1):34-39.

• Zhao Mei-Rong, LI Xue-Hu, Yao Hai-Chao, Lu Xi-Hong, Zhou Xiang*, Xin Zhi-Jun, Se Zhu, Liang Jian-Ping, Optimization of microwave--assisted extraction of osthole from root of Radix Angelica Pubescens using response surface methodology, Lishizhen Medicine and Materia Medica Research,2014, 25(5):1117-1119.

• Zhao Mei-Rong, LI Xue-Hu, Liu Yao-Ming, Yao Hai-Chao, Lu Xi-Hong, Zhou Xiang*, Xin Zhi-Jun, Se Zhu, Liang Jian-Ping, Optimization of cellulase－assisted extraction of osthole from root of Radix Angelica Pubescens using response surface methodology, Science and Technology of Food Industry, 2014, 35(1):206-209.

• Zhang Mei, Tao Lei, Zhao Feng-Wu, Lu Xi-Hong, Xin Zhi-Jun, Zhou Xiang, LI Xue-Hu, Extraction of Arteannuin from Herba Artemisiae Annuae and synthesis of Artemether, Journal of Traditional Chinese Veterinary Medicine, 2014,5(1): 21-24.

• Li Xuehu, Lu Xihong, Xin Zhijun, Zhou Xiang, Liang Jianping, Effects of 12C6 + Ion Beam Irradiation on Physiological Characteristics of Isatis indigotica Fort, Acta Laser Biology Sinica, 2013, 22(6): 515-520.

• Li Xue-Hu, Lu Xi-Hong, Liang Jian-Ping, Xin Zhi-Jun, Zhou Xiang*, Studies on the Mechanism of Interaction of Congo Red with Lysozyme by Spectroscopic Methods, Asian Journal of Chemistry, 2013, 25(11): 6146-6150.

• Wu Zheng-Qian, Li Xue-Hu, Liang Jian-Ping, Lu Xi-Hong, Xin Zhi-Jun, Zhou Xiang*,Optimizing Sequence-Ｒelated Amplified Polymorphism Amplification System for Isatis indigotica Fort, Bulletin of Botanical Research, 2015, 35(2):310-314.

•Wang Liang, Xin Zhi-Jun, Lu Xi-Hong, Yi Yun-Peng, Li Xue-Hu, Zhou Xiang, Shang Ruo-Feng, Liang Jian-Ping. Synthesis, Crystal Structure and Biological Evaluation of 14-O-[(2-chloroacetamide-6-aminopyrimidine-2-yl)thioacetyl] Mutilin, Chinese J. Struct. Chem, 2017, 36(8): 1327-1333.

•Wang Liang, Li Xuehu, Tao Hua, Zhou Xiang, Lu Xihong, Du Wenyue, Jiang Tingting, Xin Zhijun, Liang Jianping. Palladium-catalyzed intermolecular tandem cyclization reaction: a highly regioselective synthesis of functionalized 3H-spiro [isobenzofuran-1,3’-isochroman] scaffolds. Organic & Biomolecular Chemistry, 2017, 5, 2403.

已指导学生

姜婷婷  硕士研究生  085238-生物工程