基本信息
孙衍刚  男  博导  中国科学院脑科学与智能技术卓越创新中心(神经科学研究所)
电子邮件: Yangang.sun@ion.ac.cn
通信地址: 上海市徐汇区岳阳路320号
邮政编码: 200031

个人简介

孙衍刚博士任中科院神经科学研究所研究员,博士生导师。他长期从事痒觉信息处理的神经机制研究。研究成果包括:发现脊髓水平痒觉特异基因,阐明痒觉信息处理的细胞和环路机制。研究成果以通讯作者形式发表在ScienceCell Reports 等国际学术期刊上。曾获中科院****2013)、基金委杰出青年科学基金2019)等荣誉。


招生信息

招生专业
071006-神经生物学
071009-细胞生物学
招生方向
感觉信息加工,神经环路

教育背景

1999-09--2004-07   北京大学   博士
1995-09--1999-07   北京大学   学士

工作经历

   
工作简历
2012-08~现在, 中科院神经所, 研究员
2008-08~2012-07,University of Texas Medical School, 博士后
2004-11~2008-07,Washington University in St. Louis, 博士后

教授课程

《神经生物学》

出版信息

   
发表论文
[1] Gao, ZhengRun, Chen, WenZhen, Liu, MingZhe, Chen, XiaoJun, Wan, Li, Zhang, XinYan, Yuan, Lei, Lin, JunKai, Wang, Meng, Zhou, Li, Xu, XiaoHong, Sun, YanGang. Tac1-Expressing Neurons in the Periaqueductal Gray Facilitate the Itch-Scratching Cycle via Descending Regulation. NEURON[J]. 2019, 101(1): 45-+, http://dx.doi.org/10.1016/j.neuron.2018.11.010.
[2] Liu, MingZhe, Chen, XiaoJun, Liang, TongYu, Li, Qing, Wang, Meng, Zhang, XinYan, Li, YuZhuo, Sun, Qiang, Sun, YanGang. Synaptic control of spinal GRPR(+) neurons by local and long-range inhibitory inputs. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2019, 116(52): 27011-27017, [3] Yuan, Lei, Liang, TongYu, Deng, Juan, Sun, YanGang. Dynamics and Functional Role of Dopaminergic Neurons in the Ventral Tegmental Area during Itch Processing. JOURNAL OF NEUROSCIENCE[J]. 2018, 38(46): 9856-9869, [4] Mu, Di, Deng, Juan, Liu, KeFei, Wu, ZhenYu, Shi, YuFeng, Guo, WeiMin, Mao, QunQuan, Liu, XingJun, Li, Hui, Sun, YanGang. A central neural circuit for itch sensation. SCIENCE[J]. 2017, 357(6352): 695-698, https://www.webofscience.com/wos/woscc/full-record/WOS:000407793600037.
[5] Zhou, Li, Liu, MingZhe, Li, Qing, Deng, Juan, Mu, Di, Sun, YanGang. Organization of Functional Long-Range Circuits Controlling the Activity of Serotonergic Neurons in the Dorsal Raphe Nucleus. CELL REPORTS[J]. 2017, 18(12): 3018-3032, http://dx.doi.org/10.1016/j.celrep.2017.02.077.
[6] Sun, YanGang, Rupprecht, Vanessa, Zhou, Li, Dasgupta, Rajan, Seibt, Frederik, Beierlein, Michael. mGluR1 and mGluR5 Synergistically Control Cholinergic Synaptic Transmission in the Thalamic Reticular Nucleus. JOURNAL OF NEUROSCIENCE[J]. 2016, 36(30): 7886-7896, http://www.corc.org.cn/handle/1471x/2375673.
[7] 蒲慕明. Selective synaptic remodeling of amygdalocortical connections associated with fear memory. Nat Neurosci. 2016, [8] Zhao, ZhongQiu, Liu, XianYu, Jeffry, Joseph, Karunarathne, W K Ajith, Li, JinLian, Munanairi, Admire, Zhou, XuanYi, Li, Hui, Sun, YanGang, Wan, Li, Wu, ZhenYu, Kim, Seungil, Huo, FuQuan, Mo, Ping, Barry, Devin M, Zhang, ChunKui, Kim, JiYoung, Gautam, N, Renner, Kenneth J, Li, YunQing, Chen, ZhouFeng. Descending Control of Itch Transmission by the Serotonergic System via 5-HT1A-Facilitated GRP-GRPR Signaling. NEURON[J]. 2014, 84(4): 821-834, http://dx.doi.org/10.1016/j.neuron.2014.10.003.
[9] Sun, YanGang, PitaAlmenar, Juan D, Wu, ChiaShan, Renger, John J, Uebele, Victor N, Lu, HuiChen, Beierlein, Michael. Biphasic Cholinergic Synaptic Transmission Controls Action Potential Activity in Thalamic Reticular Nucleus Neurons. JOURNAL OF NEUROSCIENCE[J]. 2013, 33(5): 2048-2059, https://www.webofscience.com/wos/woscc/full-record/WOS:000314351300029.
[10] Sun, YanGang, Wu, ChiaShan, Renger, John J, Uebele, Victor N, Lu, HuiChen, Beierlein, Michael. GABAergic Synaptic Transmission Triggers Action Potentials in Thalamic Reticular Nucleus Neurons. JOURNAL OF NEUROSCIENCE[J]. 2012, 32(23): 7782-7790, https://www.webofscience.com/wos/woscc/full-record/WOS:000305091800004.
[11] Sun, YanGang, Wu, ChiaShan, Lu, HuiChen, Beierlein, Michael. Target-Dependent Control of Synaptic Inhibition by Endocannabinoids in the Thalamus. JOURNAL OF NEUROSCIENCE[J]. 2011, 31(25): 9222-9230, https://www.webofscience.com/wos/woscc/full-record/WOS:000291980500017.
[12] Liu, XianYu, Liu, ZhongChun, Sun, YanGang, Ross, Michael, Kim, Seungil, Tsai, FengFang, Li, QiFang, Jeffry, Joseph, Kim, JiYoung, Loh, Horace H, Chen, ZhouFeng. Unidirectional Cross-Activation of GRPR by MOR1D Uncouples Itch and Analgesia Induced by Opioids. CELL[J]. 2011, 147(2): 447-458, http://dx.doi.org/10.1016/j.cell.2011.08.043.
[13] Sun, YanGang, Beierlein, Michael. Receptor saturation controls short-term synaptic plasticity at corticothalamic synapses. JOURNAL OF NEUROPHYSIOLOGY[J]. 2011, 105(5): 2319-2329, https://www.webofscience.com/wos/woscc/full-record/WOS:000290710300033.
[14] Sun, YanGang, Zhao, ZhongQiu, Meng, XiuLi, Yin, Jun, Liu, XianYu, Chen, ZhouFeng. Cellular Basis of Itch Sensation. SCIENCE[J]. 2009, 325(5947): 1531-1534, https://www.webofscience.com/wos/woscc/full-record/WOS:000269887900036.
[15] Sun, YanGang, Gracias, Neilia G, Drobish, Julie Kosto, Vasko, Michael R, Gereau, Robert W, Chen, ZhouFeng. The c-kit signaling pathway is involved in the development of persistent pain. PAIN[J]. 2009, 144(1-2): 178-186, http://dx.doi.org/10.1016/j.pain.2009.04.011.
[16] Sun, YanGang, Gao, YongJing, Zhao, ZhongQiu, Huang, Bing, Yin, Jun, Taylor, Gregory A, Chen, ZhouFeng. Involvement of P311 in the affective, but not in the sensory component of pain. MOLECULAR PAIN[J]. 2008, 4(1): 23-23, https://doaj.org/article/3755947364b649d0bbd4796cb7a3da49.
[17] Sun, YanGang, Chen, ZhouFeng. A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord. NATURE[J]. 2007, 448(7154): 700-U10, https://www.webofscience.com/wos/woscc/full-record/WOS:000248598000046.

科研活动

   
科研项目
( 1 ) 多巴胺系统参与痒觉调节的机制, 主持, 国家级, 2014-01--2017-12
( 2 ) 痒觉的神经环路基础, 主持, 国家级, 2014-01--2016-12
参与会议
(1)12. Neural mechanisms underlying itch signal transmission   2017-05-18
(2)6. Differential roles of parabrachial nucleus in pain and itch   2015-11-10
(3)5. Parabrachial nucleus mediates itch-induced scratching behavior   2015-09-19

指导学生

已指导学生

周立  博士研究生  071006-神经生物学  

穆迪  博士研究生  071006-神经生物学  

现指导学生

袁雷  博士研究生  071006-神经生物学  

高郑润  博士研究生  071006-神经生物学  

陈孝军  博士研究生  071006-神经生物学  

邓娟  博士研究生  071006-神经生物学  

张欣妍  博士研究生  071006-神经生物学  

刘明哲  博士研究生  071006-神经生物学  

王蒙  硕士研究生  071006-神经生物学  

梁彤雨  博士研究生  071006-神经生物学  

林军凯  硕士研究生  071006-神经生物学