基本信息
孙超  男  硕导  中国科学院近代物理研究所
电子邮件: sunchao@impcas.ac.cn
通信地址: 甘肃省兰州市南昌路509号
邮政编码:

研究领域

1. 线粒体能量代谢与细胞自噬研究

2. 线粒体移植与肿瘤辐射敏感性研究

3. 量子生物技术在肿瘤细胞微环境检测中应用基础研究

4. 细胞内氧化还原平衡与肿瘤辐射敏感性研究

招生信息


招生专业
071011-生物物理学
086000-生物与医药
招生方向
线粒体移植在肿瘤治疗中的应用基础研究
线粒体能量代谢与肿瘤恶性表型的关系研究
活性氧自由基与肿瘤辐射敏感性关系研究

教育背景

2011-11--2014-11   National Institute of Radiological Sciences (NIRS)   共同利用研究员
2010-09--2013-07   中国科学院近代物理研究所   理学博士
2007-09--2010-07   石河子大学   医学硕士
学历

中国科学院研究生院 -- 研究生

学位

中国科学院研究生院 -- 博士

工作经历

   
工作简历
2020-01~现在, 中国科学院近代物理研究所, 青年研究员
2019-10~2020-10,National Institutes for Quantum and Radiological Sciences and Technology, 访问学者
2015-11~2019-12,中国科学院近代物理研究所, 副研究员
2013-07~2015-11,中国科学院近代物理研究所, 助理研究员

专利与奖励

   
奖励信息
(1) 甘肃省科学技术进步奖, 三等奖, 省级, 2018
(2) 甘肃省科学技术进步奖, 三等奖, 省级, 2018
(3) 甘肃省药学发展奖, 二等奖, 市地级, 2018
(4) 甘肃省环境科学技术奖, 一等奖, 市地级, 2018
(5) 郑集-张昌颖优秀论文奖, 其他, 2018
(6) 中国科学院近代物理研究所发表文章先进个人奖, 其他, 2017
(7) 甘肃省科学技术进步二等奖, 二等奖, 省级, 2016
(8) 甘肃省科学技术进步二等奖, 二等奖, 省级, 2014
专利成果
[1] 谢漪, 张红, 司婧, 甘露, 狄翠霞, 李鸿岩, 孙超, 严俊芳, 王芳. MDM2蛋白作为生物标志物在预测非小细胞肺癌患者重离子放疗的疗效中的应用. CN: CN112143811A, 2020-12-29.
[2] 狄翠霞, 张红, 张倩婧, 陈玉红, 张学甜, 徐彩鹏, 孙超, 司婧, 李鸿岩, 刘阳, 谢漪, 甘露. pladienolide B在增强宫颈癌细胞辐射敏感性中的应用. CN: CN111973589A, 2020-11-24.
[3] 狄翠霞, 张红, 周鑫, 孙超, 司婧, 甘露, 刘圆圆. PCBP1基因制备放疗增敏试剂盒的应用. 中国: CN104338150A, 2015-02-11.

出版信息

   
发表论文
[1] Li, Zheng, Li, Qiang, Wang, Xiaohu, Chen, Weiqiang, Jin, Xiaodong, Liu, Xinguo, Ye, Fei, Dai, Zhongying, Zheng, Xiaogang, Li, Ping, Sun, Chao, Liu, Xiongxiong, Zhang, Qiuning, Luo, Hongtao, Liu, Ruifeng. Hyperthermia ablation combined with transarterial chemoembolization versus monotherapy for hepatocellular carcinoma: A systematic review and meta-analysis. CANCER MEDICINE[J]. 2021, 10(23): 8432-8450, http://dx.doi.org/10.1002/cam4.4350.
[2] Bao, Xingting, Zhang, Jinhua, Huang, Guomin, Yan, Junfang, Xu, Caipeng, Dou, Zhihui, Sun, Chao, Zhang, Hong. The crosstalk between HIFs and mitochondrial dysfunctions in cancer development. CELL DEATH & DISEASEnull. 2021, 12(2): https://doaj.org/article/5c7f0ff96eec4255a2c9443b754a4975.
[3] Yan, Junfang, Xie, Yi, Si, Jing, Gan, Lu, Li, Hongyan, Sun, Chao, Di, Cuixia, Zhang, Jinhua, Huang, Guomin, Zhang, Xuetian, Zhang, Hong. Crosstalk of the Caspase Family and Mammalian Target of Rapamycin Signaling. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESnull. 2021, 22(2): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830632/.
[4] Lu, Lina, Kang, Shuhe, Sun, Chao, Sun, Chufeng, Guo, Zhong, Li, Jia, Zhang, Taofeng, Luo, Xingping, Liu, Bin. Multifunctional Nanoparticles in Precise Cancer Treatment: Considerations in Design and Functionalization of Nanocarriers. CURRENT TOPICS IN MEDICINAL CHEMISTRYnull. 2020, 20(27): 2427-2441, https://www.webofscience.com/wos/woscc/full-record/WOS:000590232100002.
[5] Sultana, Nahida, Sun, Chao, Katsube, Takanori, Wang, Bing. Biomarkers of Brain Damage Induced by Radiotherapy. DOSE-RESPONSEnull. 2020, 18(3): https://doaj.org/article/3c97be102cfe4896bc33527bc3913498.
[6] Mao, Aihong, Sun, Chao, Katsube, Takanori, Wang, Bing. A Minireview on Gastrointestinal Microbiota and Radiosusceptibility. DOSE-RESPONSEnull. 2020, 18(4): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672743/.
[7] Lu, Lina, Li, Wenjun, Sun, Chao, Kang, Shuhe, Li, Jia, Luo, Xingping, Su, Qiong, Liu, Bin, Qin, Song. Phycocyanin Ameliorates Radiation-Induced Acute Intestinal Toxicity by Regulating the Effect of the Gut Microbiota on the TLR4/Myd88/NF-kappa B Pathway. JOURNAL OF PARENTERAL AND ENTERAL NUTRITION[J]. 2020, 44(7): 1308-1317, https://www.webofscience.com/wos/woscc/full-record/WOS:000498400500001.
[8] Liu, Cuihua, Tanaka, Kaoru, Katsube, Takanori, Vares, Guillaume, Maruyama, Kouichi, Ninomiya, Yasuharu, Fardous, Zeenath, Sun, Chao, Fujimori, Akira, Moreno, Stephanie G, Nenoi, Mitsuru, Wang, Bing. Altered Response to Total Body Irradiation of C57BL/6-Tg (CAG-EGFP) Mice. DOSE-RESPONSE[J]. 2020, 18(3): https://doaj.org/article/b58530409c3c41d981752a870fe8c620.
[9] Yan, Junfang, Xie, Yi, Wang, Fang, Chen, Yuhong, Zhang, Jinhua, Dou, Zhihui, Gan, Lu, Li, Hongyan, Si, Jing, Sun, Chao, Di, Cuixia, Zhang, Hong. Carbon ion combined with tigecycline inhibits lung cancer cell proliferation by inducing mitochondrial dysfunction. LIFE SCIENCES[J]. 2020, 263: http://dx.doi.org/10.1016/j.lfs.2020.118586.
[10] Si, Jing, Zhang, Jinhua, Gan, Lu, Gu, Menghuan, Xie, Yi, Di, Cuixia, Sun, Chao, Wang, Fang, Yan, Junfang, Zhang, Hong. The effects of the Wnt/beta-catenin signaling pathway on apoptosis in HeLa cells induced by carbon ion irradiation. ONCOLOGY REPORTS[J]. 2020, 44(1): 303-312, https://www.webofscience.com/wos/woscc/full-record/WOS:000540620900026.
[11] Mao, Aihong, Tang, Jinzhou, Tang, Deping, Wang, Fang, Liao, Shiqi, Yuan, Hongxia, Tian, Caiping, Sun, Chao, Si, Jing, Zhang, Hong, Xia, Xiaojun. MicroRNA-29b-3p enhances radiosensitivity through modulating WISP1-mediated mitochondrial apoptosis in prostate cancer cells. JOURNAL OF CANCER[J]. 2020, 11(21): 6356-6364, https://www.webofscience.com/wos/woscc/full-record/WOS:000575093300007.
[12] Sun, Chao, Liu, Xiongxiong, Wang, Bing, Wang, Zhenhua, Liu, Yang, Di, Cuixia, Si, Jing, Li, Hongyan, Wu, Qingfeng, Xu, Dan, Li, Ji, Li, Gang, Wang, Yupei, Wang, Fang, Zhang, Hong. Endocytosis-mediated mitochondrial transplantation: Transferring normal human astrocytic mitochondria into glioma cells rescues aerobic respiration and enhances radiosensitivity. THERANOSTICS[J]. 2019, 9(12): 3595-3607, https://www.webofscience.com/wos/woscc/full-record/WOS:000469953000015.
[13] Wang, Fang, Mao, Aihong, Tang, Jinzhou, Zhang, Qianjing, Yan, Junfang, Wang, Yupei, Di, Cuixia, Gan, Lu, Sun, Chao, Zhang, Hong. microRNA-16-5p enhances radiosensitivity through modulating Cyclin D1/E1-pRb-E2F1 pathway in prostate cancer cells. JOURNAL OF CELLULAR PHYSIOLOGY[J]. 2019, 234(8): 13182-13190, https://www.webofscience.com/wos/woscc/full-record/WOS:000467240800093.
[14] Li, Hongyan, Zhang, Weihong, Zhang, Hong, Xie, Yi, Sun, Chao, Di, Cuixia, Si, Jing, Gan, Lu, Yan, Junfang. Mitochondrial proteomics reveals the mechanism of spermatogenic cells apoptosis induced by carbon ion radiation in zebrafish. JOURNAL OF CELLULAR PHYSIOLOGY[J]. 2019, 234(12): 22439-22449, [15] Di, Cuixia, Syafrizayanti, Zhang, Qianjing, Chen, Yuhong, Wang, Yupei, Zhang, Xuetian, Liu, Yang, Sun, Chao, Zhang, Hong, Hoheisel, Jorg D. Function, clinical application, and strategies of Pre-mRNA splicing in cancer. CELL DEATH AND DIFFERENTIATIONnull. 2019, 26(7): 1181-1194, https://www.webofscience.com/wos/woscc/full-record/WOS:000470970300001.
[16] Lu, Lina, Sun, Chao, Su, Qiong, Wang, Yanbin, Li, Jia, Guo, Zhong, Chen, Lihua, Zhang, Hong. Radiation-induced lung injury: latest molecular developments, therapeutic approaches, and clinical guidance. CLINICAL AND EXPERIMENTAL MEDICINEnull. 2019, 19(4): 417-426, https://www.webofscience.com/wos/woscc/full-record/WOS:000491035600002.
[17] Mao, Aihong, Guo, Hongyun, Liu, Yang, Wang, Fang, Tang, Jinzhou, Liao, Shiqi, Zhang, Yongdong, Sun, Chao, Xia, Xiaojun, Zhang, Hong. Exogenous melatonin modulates carbon ion radiation-induced immune dysfunction in mice. TOXICOLOGY[J]. 2019, 417: 35-41, http://dx.doi.org/10.1016/j.tox.2019.01.019.
[18] Zhang, Jinhua, Si, Jing, Gan, Lu, Di, Cuixia, Xie, Yi, Sun, Chao, Li, Hongyan, Guo, Menghuan, Zhang, Hong. Research progress on therapeutic targeting of quiescent cancer cells. ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY[J]. 2019, 47(1): 2810-2819, https://www.webofscience.com/wos/woscc/full-record/WOS:000474568400005.
[19] Lu Gan, Zhenhua Wang, Jing Si, Rong Zhou, Chao Sun, Yang Liu, Yancheng Ye, Yanshan Zhang, Zhiyuan Liu, Hong Zhang. Protective effect of mitochondrial-targeted antioxidant MitoQ against iron ion 56Fe radiation induced brain injury in mice. Toxicology and Applied Pharmacology. 2018, 341: 1-7, http://dx.doi.org/10.1016/j.taap.2018.01.003.
[20] 杨世锋, 孙超, 王玉佩, 陈玉红, 张倩婧, 张红. 线粒体移植在治疗线粒体缺陷疾病中的研究进展. 生物化学与生物物理进展[J]. 2018, 45(3): 297-304, http://lib.cqvip.com/Qikan/Article/Detail?id=674827203.
[21] Di, Cuixia, Zhang, Qianjing, Wang, Yupei, Wang, Fang, Chen, Yuhong, Gan, Lu, Zhou, Rong, Sun, Chao, Li, Hongyan, Zhang, Xuetian, Yang, Hongying, Zhang, Hong. Exosomes as drug carriers for clinical application. ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGYnull. 2018, 46: S564-S570, https://www.webofscience.com/wos/woscc/full-record/WOS:000460141900054.
[22] 杨世锋, 孙超, 李昭君, 王玉佩, 张红. 线粒体移植增强人神经胶质瘤U87细胞的辐射敏感性. 中国生物化学与分子生物学报[J]. 2018, 34(12): 1299-1306, http://lib.cqvip.com/Qikan/Article/Detail?id=6100072971.
[23] Gan, Lu, Wang, Zhenhua, Si, Jing, Zhou, Rong, Sun, Chao, Liu, Yang, Ye, Yancheng, Zhang, Yanshan, Liu, Zhiyuan, Zhang, Hong. Protective effect of mitochondrial-targeted antioxidant MitoQ against iron ion Fe-56 radiation induced brain injury in mice. TOXICOLOGY AND APPLIED PHARMACOLOGY[J]. 2018, 341: 1-7, [24] Yang ShiFeng, Sun Chao, Wang YuPei, Chen YuHong, Zhang QianJing, Zhang Hong. Advances of Mitochondrial Transplantation Therapy for The Mitochondrial Deficiency Diseases. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS[J]. 2018, 45(3): 297-304, https://www.webofscience.com/wos/woscc/full-record/WOS:000428323500002.
[25] Sun, Chao, Liu, Xiongxiong, Di, Cuixia, Wang, Zhenhua, Mi, Xiangquan, Liu, Yang, Zhao, Qiuyue, Mao, Aihong, Chen, Weiqiang, Gan, Lu, Zhang, Hong. MitoQ regulates autophagy by inducing a pseudo-mitochondrial membrane potential. AUTOPHAGY[J]. 2017, 13(4): 730-738, [26] Wang, Yupei, Liu, Qing, Zhao, Weiping, Zhou, Xin, Miao, Guoying, Sun, Chao, Zhang, Hong. NADPH Oxidase Activation Contributes to Heavy Ion Irradiation-Induced Cell Death. DOSE-RESPONSE[J]. 2017, 15(1): https://doaj.org/article/08d5928f001647eba83e52a6f3cac90c.
[27] Sun, Chao, Gan, Lu, Zhang, Hong. Disturbance of redox status enhances radiosensitivity of hepatocellular carcinoma. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINEnull. 2017, 40: S60-S60, https://www.webofscience.com/wos/woscc/full-record/WOS:000411659300225.
[28] Zhao, Qiuyue, Mao, Aihong, Guo, Ruoshui, Zhang, Liping, Yan, Jiawei, Sun, Chao, Tang, Jinzhou, Ye, Yancheng, Zhang, Yanshan, Zhang, Hong. Suppression of radiation-induced migration of non-small cell lung cancer through inhibition of Nrf2-Notch Axis. ONCOTARGET[J]. 2017, 8(22): 36603-36613, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000403230000093.
[29] Zhang Hong. MitoQ Regulates Autophagy by Inducing Pseudo-Mitochondrial Membrane Potential (PMMP). Autophagy. 2017, [30] Mi, Xiangquan, Wang, Chunming, Sun, Chao, Chen, Xu, Huo, Xiang, Zhang, Yiming, Li, Gang, Xu, Bo, Zhang, Jun, Xie, Jianxin, Wang, Zhenhua, Li, Ji. Xanthohumol induces paraptosis of leukemia cells through p38 mitogen activated protein kinase signaling pathway. ONCOTARGET[J]. 2017, 8(19): 31297-31304, https://www.webofscience.com/wos/woscc/full-record/WOS:000401003200054.
[31] Zhang, Luwei, Yan, Jiawei, Liu, Yang, Zha, Qiuyue, Di, Cuixia, Chao, Sun, Jie, Li, Liu, Yuanyuan, Zhang, Hong. Contribution of caspase-independent pathway to apoptosis in malignant glioma induced by carbon ion beams. ONCOLOGY REPORTS[J]. 2017, 37(5): 2994-3000, https://www.webofscience.com/wos/woscc/full-record/WOS:000400629500052.
[32] Zhao, Qiuyue, Mao, Aihong, Yan, Jiawei, Sun, Chao, Di, Cuixia, Zhou, Xin, Li, Hongyan, Guo, Ruoshui, Zhang, Hong. Downregulation of Nrf2 promotes radiation-induced apoptosis through Nrf2 mediated Notch signaling in non-small cell lung cancer cells. INTERNATIONAL JOURNAL OF ONCOLOGY[J]. 2016, 48(2): 765-773, https://www.webofscience.com/wos/woscc/full-record/WOS:000366897500033.
[33] Liu, X X, Sun, C, Jin, X D, Li, P, Zheng, X G, Zhao, T, Li, Q. Genistein sensitizes sarcoma cells in vitro and in vivo by enhancing apoptosis and by inhibiting DSB repair pathways. JOURNAL OF RADIATION RESEARCH[J]. 2016, 57(3): 227-237, http://www.corc.org.cn/handle/1471x/2374614.
[34] Gan, Lu, Wang, Zhenhua, Zhang, Hong, Zhou, Xin, Zhou, Hui, Sun, Chao, Si, Jing, Zhou, Rong, Ma, Chengjun, Li, Ji. Endothelium-independent vasorelaxant effect of 20(S)-protopanaxadiol on isolated rat thoracic aorta. ACTA PHARMACOLOGICA SINICA[J]. 2016, 37(12): 1555-1562, https://www.webofscience.com/wos/woscc/full-record/WOS:000389704500004.
[35] Liu, Xiongxiong, Sun, Chao, Liu, Bingtao, Jin, Xiaodong, Li, Ping, Zheng, Xiaogang, Zhao, Ting, Li, Feifei, Li, Qiang. Genistein mediates the selective radiosensitizing effect in NSCLC A549 cells via inhibiting methylation of the keap1 gene promoter region. ONCOTARGET[J]. 2016, 7(19): 27267-27279, https://www.webofscience.com/wos/woscc/full-record/WOS:000377741700027.
[36] Mao, Aihong, Zhao, Qiuyue, Zhou, Xin, Sun, Chao, Si, Jing, Zhou, Rong, Gan, Lu, Zhang, Hong. MicroRNA-449a enhances radiosensitivity by downregulation of c-Myc in prostate cancer cells. SCIENTIFIC REPORTS[J]. 2016, 6: https://www.webofscience.com/wos/woscc/full-record/WOS:000376862000001.
[37] Mao, Aihong, Liu, Yang, Wang, Yali, Zhao, Qiuyue, Zhou, Xin, Sun, Chao, Di, Cuixia, Si, Jing, Gan, Lu, Zhang, Hong. miR-449a enhances radiosensitivity through modulating pRb/E2F1 in prostate cancer cells. TUMOR BIOLOGY[J]. 2016, 37(4): 4831-4840, https://www.webofscience.com/wos/woscc/full-record/WOS:000374904500064.
[38] Sun, Chao, Wang, ZhenHua, Liu, XiongXiong, Yang, LiNa, Wang, Yali, Liu, Yang, Mao, AiHong, Liu, YuanYuan, Zhou, Xin, Di, CuiXia, Gan, Lu, Zhang, Hong. Disturbance of redox status enhances radiosensitivity of hepatocellular carcinoma. AMERICAN JOURNAL OF CANCER RESEARCH[J]. 2015, 5(4): 1368-1381, https://www.webofscience.com/wos/woscc/full-record/WOS:000356495900008.
[39] 王亚丽, 孙超, 张昕, 谢漪, 杨立娜, 刘圆圆, 赵邱越, 甘露, 张红. MST-312对人肝癌HepG2细胞辐射敏感性影响研究. 中华肿瘤防治杂志. 2015, 22(1): 1-6, http://lib.cqvip.com/Qikan/Article/Detail?id=663190006.
[40] Yang, Lina, Liu, Yuanyuan, Sun, Chao, Yang, Xinrui, Yang, Zhen, Ran, Juntao, Zhang, Qiuning, Zhang, Hong, Wang, Xinyu, Wang, Xiaohu. Inhibition of DNA-PKcs enhances radiosensitivity and increases the levels of ATM and ATR in NSCLC cells exposed to carbon ion irradiation. ONCOLOGY LETTERS[J]. 2015, 10(5): 2856-2864, https://www.webofscience.com/wos/woscc/full-record/WOS:000364324800028.
[41] Liu, Yang, Zhang, Luwei, Liu, Yuanyuan, Sun, Chao, Zhang, Hong, Miao, Guoying, Di, Cui Xia, Zhou, Xin, Zhou, Rong, Wang, Zhenhua. DNA-PKcs Deficiency Inhibits Glioblastoma Cell-Derived Angiogenesis After Ionizing Radiation. JOURNAL OF CELLULAR PHYSIOLOGY[J]. 2015, 230(5): 1094-1103, https://www.webofscience.com/wos/woscc/full-record/WOS:000349301000014.
[42] Gan Lu, Wang Zhen Hua, Zhang Hong, Zhou Rong, Sun Chao, Liu Yang, Si Jing, Liu Yuan Yuan, Wang Zhen Guo. Protective Effects of Shikonin on Brain Injury Induced by Carbon Ion Beam Irradiation in Mice. BIOMEDICAL AND ENVIRONMENTAL SCIENCESnull. 2015, 28(2): 148-151, http://lib.cqvip.com/Qikan/Article/Detail?id=663998272.
[43] Di, Cuixia, Sun, Chao, Li, Hongyan, Si, Jing, Zhang, Hong, Han, Lu, Zhao, Qiuyue, Liu, Yang, Liu, Bin, Miao, Guoying, Gan, Lu, Liu, Yuanyuan. Diallyl disulfide enhances carbon ion beams-induced apoptotic cell death in cervical cancer cells through regulating Tap73/Delta Np73. CELL CYCLE[J]. 2015, 14(23): 3725-3733, https://www.webofscience.com/wos/woscc/full-record/WOS:000366450600013.
[44] Di, Cuixia, Han, Lu, Zhang, Hong, Xu, Shuai, Mao, Aihong, Sun, Chao, Liu, Yang, Si, Jing, Li, Hongyan, Zhou, Xin, Liu, Bing, Miao, Guoying. Diallyl disulfide attenuated carbon ion irradiation-induced apoptosis in mouse testis through changing the ratio of Tap73/Delta Np73 via mitochondrial pathway. SCIENTIFIC REPORTS[J]. 2015, 5: https://www.webofscience.com/wos/woscc/full-record/WOS:000363947600001.
[45] Zhou, Xin, Ma, Xiaofei, Wang, Zhenhua, Sun, Chao, Wang, Yupei, He, Yang, Zhang, Hong. Radiation-induced hyperproliferation of intestinal crypts results in elevated genome instability with inactive p53-related genomic surveillance. LIFE SCIENCES[J]. 2015, 143: 80-88, http://dx.doi.org/10.1016/j.lfs.2015.10.028.
[46] GAN Lu, WANG Zhen Hua, ZHANG Hong, ZHOU Rong, SUN Chao, LIU Yang, SI Jing, LIU Yuan Yuan, WANG Zhen Guo. Protective Effects of Shikonin on Brain Injury Induced by Carbon Ion Beam Irradiation in Mice. 生物医学与环境科学:英文版. 2015, 28(2): 148-151, http://lib.cqvip.com/Qikan/Article/Detail?id=663998272.
[47] Wang, Yali, Sun, Chao, Mao, Aihong, Zhang, Xin, Zhou, Xin, Wang, Zhenhua, Zhang, Hong. Radiosensitization to X-ray radiation by telomerase inhibitor MST-312 in human hepatoma HepG2 cells. LIFE SCIENCES[J]. 2015, 123: 43-50, http://dx.doi.org/10.1016/j.lfs.2014.12.027.
[48] Liu, Yuanyuan, Liu, Yang, Zhang, Hong, Sun, Chao, Zhao, Qiuyue, Di, Cixia, Li, Hongyan, Gan, Lu, Wang, Yali. Effects of carbon-ion beam irradiation on the angiogenic response in lung adenocarcinoma A549 cells. CELL BIOLOGY INTERNATIONAL[J]. 2014, 38(11): 1304-1310, https://www.webofscience.com/wos/woscc/full-record/WOS:000342798200009.
[49] Sun, Chao, Wang, Zhenhua, Liu, Yang, Liu, Yuanyuan, Li, Hongyan, Di, Cuixia, Wu, Zhenhua, Gan, Lu, Zhang, Hong. Carbon Ion Beams Induce Hepatoma Cell Death by NADPH Oxidase-Mediated Mitochondrial Damage. JOURNAL OF CELLULAR PHYSIOLOGY[J]. 2014, 229(1): 100-107, https://www.webofscience.com/wos/woscc/full-record/WOS:000327883100014.
[50] Mao, Aihong, Liu, Yang, Zhang, Hong, Di, Cuixia, Sun, Chao. microRNA Expression and Biogenesis in Cellular Response to Ionizing Radiation. DNA AND CELL BIOLOGY[J]. 2014, 33(10): 667-679, https://www.webofscience.com/wos/woscc/full-record/WOS:000342299200003.
[51] Yang Liu, Yuanyuan Liu, Chao Sun, Lu Gan, Luwei Zhang, Aihong Mao, Yuting Du, Rong Zhou, Hong Zhang. Carbon Ion Radiation Inhibits Glioma and Endothelial Cell Migration Induced by Secreted VEGF. PLOS ONE[J]. 2014, 9(6): https://doaj.org/article/d227a6ef965d427284f3a59f6da48083.
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科研活动

   
科研项目
( 1 ) 辐射诱导肿瘤细胞死亡新途径:NADPH氧化酶启动线粒体恶性循环损伤, 主持, 国家级, 2016-01--2018-12
( 2 ) 异甘草素抑制Nrf2蛋白及肿瘤辐射增敏作用研究, 主持, 部委级, 2014-01--2016-12
( 3 ) 重离子克服癌细胞辐射抗拒的分子机理研究, 参与, 国家级, 2015-01--2018-12
( 4 ) 基于细胞力学特性研究辐射对神经胶质瘤细胞转移潜能的影响及调控机制, 参与, 国家级, 2014-01--2016-12
( 5 ) 精准辐射防护新策略:线粒体假膜电势介导选择性自噬研究, 主持, 国家级, 2018-01--2021-12
( 6 ) 线粒体移植在胰腺癌精准放疗增敏作用中的研究, 主持, 部委级, 2018-01--2021-12
( 7 ) 中国科学院青年创新促进会会员项目, 主持, 部委级, 2020-01--2023-12
参与会议
(1)DISTURBANCE OF REDOX STATUS ENHANCES RADIOSENSITIVITY OF HEPATOCELLULAR CARCINOMA   2017-06-26
(2)重离子治癌基础研究   第二届全国重离子治癌高端学术论坛   2016-12-27
(3)线粒体假膜电势诱导细胞自噬研究   泰山学术论坛——线粒体与健康衰老专题   2016-11-15
(4)重离子束诱导肿瘤细胞死亡新途径:NADPH氧化酶介导线粒体损伤恶性循环   中国第十届辐射与环境生物物理大会暨国际研讨会   2016-04-22
(5)NADPH oxidase-mediated damage of mitochondrial: a new mechanism for Carbin Ions induced HepG2 cell death   第一届全国重离子治癌高端学术论坛   2015-11-21
(6)Carbon Ion Beams Induce Mitochondrial Vicious Cycle Damage by NADPH Oxidase Activation   2015-09-13

合作情况

与烟台大学生命科学学院“线粒体与健康衰老重点实验室”保持长期合作关系

在心脑血管生理指标检测以及离体心脏实验平台长期保持资源仪器共享