081203-计算机应用技术

搜索引擎，应用算法学，生物信息学

1991-09--1997-07   清华大学计算机科学与技术系   博士
1986-09--1991-07   清华大学计算机科学与技术系   学士

清华大学 19910901--19970701 研究生毕业

清华大学 19910901--19970701 工学博士学位

   

（1） 中国计算机学会技术发明奖《蛋白质组海量质谱数据深度解析关键技术及应用》, 一等奖, 其他, 2019
（2） 中国科学院优秀导师奖, 院级, 2013
（3） 中创软件人才奖, 其他, 2009
（4） 数字视频广播编码传输与接收系统, 二等奖, 国家级, 2000

[1] 陈镇霖, 毛鹏志, 谭永卿, 迟浩, 贺思敏. 一种可断裂交联肽段鉴定方法、鉴定结果评估筛选方法. CN: CN114049915A, 2022-02-15.

[2] 王振振, 孙瑞祥, 迟浩, 贺思敏. 一种基于离子索引的整体蛋白质鉴定方法. CN: CN111524549A, 2020-08-11.

[3] 周文婧, 杨皓, 曾文锋, 张昆, 迟浩, 贺思敏. 肽段-谱图匹配可信度检验方法、系统、存储介质及装置. CN: CN110349621A, 2019-10-18.

[4] 张晓今, 曾文锋, 吴建强, 孙瑞祥, 贺思敏. 一种基于正则表达式的N糖结构库构建方法与系统. CN: CN108052801A, 2018-05-18.

[5] 杨皓, 迟浩, 曾文锋, 周文婧, 刘超, 贺思敏. 一种从头测序方法. CN: CN107729719A, 2018-02-23.

[6] 杨皓, 迟浩, 曾文锋, 周文婧, 王钊伟, 王瑞敏, 牛秀南, 陈振霖, 刘超, 贺思敏. 氨基酸可信度和修饰位点定位的评估方法. CN: CN107622184A, 2018-01-23.

[7] 王瑞敏, 孙瑞祥, 迟浩, 曾文锋, 刘超, 贺思敏. 一种基于离子索引的整体蛋白质鉴定方法与系统. CN: CN107563148A, 2018-01-09.

[8] 杨皓, 迟浩, 周文婧, 何昆, 曾文锋, 刘超, 孙瑞祥, 贺思敏. 从头测序方法及装置. CN: CN106770605A, 2017-05-31.

[9] 涂慧君, 刘超, 迟浩, 贺思敏. 一种肽段液相色谱保留时间预测方法及系统. CN: CN106248844A, 2016-12-21.

[10] 尹吉澧, 孟佳明, 刘超, 迟浩, 陈镇霖, 孙瑞祥, 董梦秋, 贺思敏. 一种基于半监督学习的交联质谱多谱排序方法. CN: CN106529204A, 2017-03-22.

[11] 樊盛博, 迟浩, 孟佳明, 卢珊, 尹吉澧, 孙瑞祥, 董梦秋, 贺思敏. 一种对多肽交联肽段进行质谱鉴定的假发现率控制方法. CN: CN106198706A, 2016-12-07.

[12] 曾文锋, 刘铭琪, 张晓今, 吴建强, 张扬, 孙瑞祥, 杨芃原, 贺思敏. 一种完整糖肽鉴定的方法与系统. CN: CN106018535A, 2016-10-12.

[13] 孟佳明, 樊盛博, 迟浩, 卢珊, 孙瑞祥, 董梦秋, 贺思敏. 一种交联二肽快速鉴定方法. CN: CN106033501A, 2016-10-19.

[14] 邬龙, 曾文锋, 袁作飞, 刘超, 孟佳明, 贺思敏. 串联质谱数据母离子检测模型训练方法及母离子检测方法. CN: CN104215729A, 2014-12-17.

[15] 何昆, 曾文锋, 付岩, 迟浩, 贺思敏. 一种串联质谱谱图鉴定方法. CN: CN104182658A, 2014-12-03.

[16] 罗兰, 孙瑞祥, 迟浩, 贺思敏. 一种蛋白质翻译后修饰的定位方法及系统. CN: CN104134015A, 2014-11-05.

[17] 刘超, 宋春青, 迟浩, 孙瑞祥, 董梦秋, 贺思敏. 一种检测差异表达蛋白质的方法. CN: CN103776891A, 2014-05-07.

[18] 迟浩, 陈海丰, 孙瑞祥, 董梦秋, 贺思敏. 一种基于HCD与ETD质谱图的肽段从头测序方法及系统. CN: CN103852513A, 2014-06-11.

[19] 迟浩, 孙瑞祥, 王乐珩, 张文力, 贺思敏. 开放式蛋白质鉴定的数据库搜索方法及其系统. CN: CN103810200A, 2014-05-21.

[20] 张文力, 迟浩, 路远征, 王乐珩, 赵晓芳, 贺思敏. 一种开放式蛋白质鉴定的分布式加速方法及其系统. CN: CN103678950A, 2014-03-26.

[21] 周郴, 迟浩, 王乐珩, 李由, 吴研洁, 付岩, 孙瑞祥, 贺思敏. 一种用后缀数组加速大规模蛋白质鉴定的方法及其系统. CN: CN102467616A, 2012-05-23.

[22] 孙瑞祥, 董梦秋, 宋春青, 迟浩, 杨兵, 王乐珩, 付岩, 贺思敏. 电子转运裂解质谱预处理与鉴定方法. CN: CN102043011A, 2011-05-04.

[23] 袁作飞, 刘超, 王海鹏, 付岩, 孙瑞祥, 贺思敏. 一种提高单同位素峰判断准确率的方法和系统. CN: CN102445544A, 2012-05-09.

[24] 王乐珩, 王文平, 迟浩, 吴妍洁, 周郴, 付岩, 孙瑞祥, 贺思敏. 一种蛋白质鉴定的大规模分布式并行加速方法及其系统. CN: CN102411680B, 2014-03-26.

[25] 王乐珩, 王文平, 迟浩, 吴妍洁, 周郴, 付岩, 孙瑞祥, 贺思敏. 一种蛋白质鉴定的大规模分布式并行加速方法及其系统. CN: CN102411680A, 2012-04-11.

[26] 王乐珩, 王文平, 迟浩, 吴妍洁, 周郴, 付岩, 孙瑞祥, 贺思敏. 一种蛋白质鉴定的大规模分布式并行加速方法及其系统. CN: CN102411666A, 2012-04-11.

[27] 叶叮, 付岩, 孙瑞祥, 贺思敏. 谱库的生成方法和串联质谱谱图鉴定方法. CN: CN101871945A, 2010-10-27.

[28] 付岩, 贺思敏, 王海鹏, 孙瑞祥. 一种蛋白质翻译后修饰的发现方法. CN: CN101477089B, 2012-06-13.

[29] 李由, 贺思敏, 付岩, 袁作飞, 迟浩, 王海鹏, 王乐珩, 孙瑞祥. 一种对字符串排序和查找的方法. CN: CN101751416A, 2010-06-23.

[30] 李由, 李德泉, 王乐珩, 迟浩, 王海鹏, 付岩, 孙瑞祥, 贺思敏, 刘超, 袁作飞, 王文平, 秀丽蕴. 一种规模化蛋白质鉴定中的索引加速方法及相应的系统. CN: CN101714187A, 2010-05-26.

[31] 高文, 张京芬, 贺思敏. 一种质谱质量测量误差的预测方法. CN: CN101196498A, 2008-06-11.

[32] 高文, 张京芬, 贺思敏. 基于质谱数据同位素模式的质谱有效峰选取方法. CN: CN101055558B, 2010-10-06.

[33] 高文, 张京芬, 贺思敏. 一种质谱数据处理中噪音基线识别方法. CN: CN101055559A, 2007-10-17.

[34] 贺思敏, 孙书韬, 赵巍, 郑燕峰, 高文. 一种支持均匀交换的路由器交换结构及服务质量保证方法. CN: CN1933441A, 2007-03-21.

[35] 高文, 张京芬, 蔡津津, 贺思敏, 曾嵘, 陈润生, 王海鹏. 用串联质谱中碎片离子的同位素峰预测离子分子式的方法. CN: CN1773276A, 2006-05-17.

[36] 高文, 付 岩, 李德泉, 孙瑞祥, 贺思敏, 杨 强, 曾 嵘, 周 虎, 陈益强, 王晓彪. 一种使用串联质谱数据鉴定肽的方法. CN: CN1769891A, 2006-05-10.

[37] 贺思敏, 赵巍, 孙书韬, 高文. 一种用于数字视频广播传输网络的均匀复用方法. CN: CN1258289C, 2006-05-31.

   

[1] 周文婧, 曾文锋, 迟浩, 贺思敏. 蛋白质组学肽段鉴定可信度评价方法. 生物化学与生物物理进展[J]. 2023, 50(1): 109-125, http://lib.cqvip.com/Qikan/Article/Detail?id=7109085719.
[2] 陈镇霖, 曹勇, 贺思敏. 化学交联质谱技术的研究进展. 生物化学与生物物理进展[J]. 2022, 49(4): 737-758, http://lib.cqvip.com/Qikan/Article/Detail?id=7107200035.
[3] Zhou, WenJing, Wei, ZhuoHong, He, SiMin, Chi, Hao. pValid 2: A deep learning based validation method for peptide identification in shotgun proteomics with increased discriminating power. JOURNAL OF PROTEOMICS[J]. 2022, 251: http://dx.doi.org/10.1016/j.jprot.2021.104414.
[4] Zeng, WenFeng, Cao, WeiQian, Liu, MingQi, He, SiMin, Yang, PengYuan. Precise, fast and comprehensive analysis of intact glycopeptides and modified glycans with pGlyco3. NATURE METHODS[J]. 2021, 18(12): 1515-+, http://dx.doi.org/10.1038/s41592-021-01306-0.
[5] Chen, ZhenLin, Mao, PengZhi, Zeng, WenFeng, Chi, Hao, He, SiMin. pDeepXL: MS/MS Spectrum Prediction for Cross-Linked Peptide Pairs by Deep Learning. JOURNAL OF PROTEOME RESEARCH[J]. 2021, 20(5): 2570-2582, http://dx.doi.org/10.1021/acs.jproteome.0c01004.
[6] Hao Yang, YanChang Li, MingZhi Zhao, FeiLin Wu, Xi Wang, WeiDi Xiao, YiHao Wang, JunLing Zhang, FuQiang Wang, Feng Xu, WenFeng Zeng, Christopher M Overall, SiMin He, Hao Chi, Ping Xu. Precision De Novo Peptide Sequencing Using Mirror Proteases of Ac-LysargiNase and Trypsin for Large-scale Proteomics *. MOLECULARCELLULARPROTEOMICSMCP[J]. 2019, 18(4): 773-785, http://dx.doi.org/10.1074/mcp.TIR118.000918.
[7] ZhenLin Chen, JiaMing Meng, Yong Cao, JiLi Yin, RunQian Fang, ShengBo Fan, Chao Liu, WenFeng Zeng, YueHe Ding, Dan Tan, Long Wu, WenJing Zhou, Hao Chi, RuiXiang Sun, MengQiu Dong, SiMin He. A high-speed search engine pLink 2 with systematic evaluation for proteome-scale identification of cross-linked peptides. NATURE COMMUNICATIONS[J]. 2019, 10(1): 1-12, [8] Zeng, WenFeng, Zhou, XieXuan, Zhou, WenJing, Chi, Hao, Zhan, Jianfeng, He, SiMin. MS/MS Spectrum Prediction for Modified Peptides Using pDeep2 Trained by Transfer Learning. ANALYTICAL CHEMISTRY[J]. 2019, 91(15): 9724-9731, [9] Zuo, MeiQing, Sun, RuiXiang, Fang, RunQian, He, SiMin, Dong, MengQiu. Characterization of collision-induced dissociation of deprotonated peptides of 4-16 amino acids using high-resolution mass spectrometry. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY[J]. 2019, 445: http://dx.doi.org/10.1016/j.ijms.2019.116186.
[10] Alexander X Jones, Yong Cao, YuLiang Tang, JianHua Wang, YueHe Ding, Hui Tan, ZhenLin Chen, RunQian Fang, Jili Yin, RongChang Chen, Xing Zhu, Yang She, Niu Huang, Feng Shao, Keqiong Ye, RuiXiang Sun, SiMin He, Xiaoguang Lei, MengQiu Dong. Improving mass spectrometry analysis of protein structures with arginine-selective chemical cross-linkers. NATURE COMMUNICATIONS[J]. 2019, 10(1): 1-11, http://dx.doi.org/10.1038/s41467-019-11917-z.
[11] Zhou, WenJing, Yang, Hao, Zeng, WenFeng, Zhang, Kun, Chi, Hao, He, SiMin. pValid: Validation Beyond the Target-Decoy Approach for Peptide Identification in Shotgun Proteomics. JOURNAL OF PROTEOME RESEARCH[J]. 2019, 18(7): 2747-2758, http://dx.doi.org/10.1021/acs.jproteome.8b00993.
[12] Yang, Hao, Chi, Hao, Zeng, WenFeng, Zhou, WenJing, He, SiMin. pNovo 3: precise de novo peptide sequencing using a learning-to-rank framework. BIOINFORMATICS[J]. 2019, 35(14): I183-I190, [13] Yang, Hao, Li, YanChang, Zhao, MingZhi, Wu, FeiLin, Wang, Xi, Xiao, WeiDi, Wang, YiHao, Zhang, JunLing, Wang, FuQiang, Xu, Feng, Zengt, WenFeng, Overall, Christopher M, He, SiMin, Chi, Hao, Xu, Ping. Precision De Novo Peptide Sequencing Using Mirror Proteases of Ac-LysargiNase and Trypsin for Large-scale Proteomics. MOLECULAR & CELLULAR PROTEOMICS[J]. 2019, 18(4): 773-785, http://dx.doi.org/10.1074/mcp.TIR118.000918.
[14] Lu Shan, Cao Yong, Fan Shengbo, Chen Zhenlin, Fang Runqian, He Simin, Dong Mengqiu. Mapping disulfide bonds from sub-micrograms of purified proteins or micrograms of complex protein mixtures. 生物物理学报：英文版[J]. 2018, 4(2): 68-81, http://lib.cqvip.com/Qikan/Article/Detail?id=675314443.
[15] Chi, Hao, Liu, Chao, Yang, Hao, Zeng, WenFeng, Wu, Long, Zhou, WenJing, Wang, RuiMin, Niu, XiuNan, Ding, YueHe, Zhang, Yao, Wang, ZhaoWei, Chen, ZhenLin, Sun, RuiXiang, Liu, Tao, Tan, GuangMing, Dong, MengQiu, Xu, Ping, Zhang, PeiHeng, He, SiMin. Comprehensive identification of peptides in tandem mass spectra using an efficient open search engine. NATURE BIOTECHNOLOGY[J]. 2018, 36(11): 1059-+, http://dx.doi.org/10.1038/nbt.4236.
[16] Yang, Hao, Chi, Hao, Zhou, WenJing, Zeng, WenFeng, Liu, Chao, Wang, RuiMin, Wang, ZhaoWei, Niu, XiuNan, Chen, ZhenLin, He, SiMin. pSite: Amino Acid Confidence Evaluation for Quality Control of De Novo Peptide Sequencing and Modification Site Localization. JOURNAL OF PROTEOME RESEARCH[J]. 2018, 17(1): 119-128, https://www.webofscience.com/wos/woscc/full-record/WOS:000419749800012.
[17] Ding, YueHe, Gong, Zhou, Dong, Xu, Liu, Kan, Liu, Zhu, Liu, Chao, He, SiMin, Dong, MengQiu, Tang, Chun. Modeling Protein Excited-state Structures from "Over-length" Chemical Cross-links. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2017, 292(4): 1187-1196, http://dx.doi.org/10.1074/jbc.M116.761841.
[18] Zhou, XieXuan, Zeng, WenFeng, Chi, Hao, Luo, Chunjie, Liu, Chao, Zhan, Jianfeng, He, SiMin, Zhang, Zhifei. pDeep: Predicting MS/MS Spectra of Peptides with Deep Learning. ANALYTICAL CHEMISTRY[J]. 2017, 89(23): 12690-12697, http://dx.doi.org/10.1021/acs.analchem.7b02566.
[19] MingQi Liu, WenFeng Zeng, Pan Fang, WeiQian Cao, Chao Liu, GuoQuan Yan, Yang Zhang, Chao Peng, JianQiang Wu, XiaoJin Zhang, HuiJun Tu, Hao Chi, RuiXiang Sun, Yong Cao, MengQiu Dong, BiYun Jiang, JiangMing Huang, HuaLi Shen, Catherine C L Wong, SiMin He, PengYuan Yang. pGlyco 2.0 enables precision N-glycoproteomics with comprehensive quality control and one-step mass spectrometry for intact glycopeptide identification. NATURE COMMUNICATIONS[J]. 2017, 8(1): https://doaj.org/article/06238f004d55472fb185f1b06f0ba1c5.
[20] Yang, Hao, Chi, Hao, Zhou, WenJing, Zeng, WenFeng, He, Kun, Liu, Chao, Sun, RuiXiang, He, SiMin. Open-pNovo: De Novo Peptide Sequencing with Thousands of Protein Modifications. JOURNALOFPROTEOMERESEARCH[J]. 2017, 16(2): 645-654, https://www.webofscience.com/wos/woscc/full-record/WOS:000393539600026.
[21] Tan, Dan, Li, Qiang, Zhang, MeiJun, Liu, Chao, Ma, Chengying, Zhang, Pan, Ding, YueHe, Fan, ShengBo, Tao, Li, Yang, Bing, Li, Xiangke, Ma, Shoucai, Liu, Junjie, Feng, Boya, Liu, Xiaohui, Wang, HongWei, He, SiMin, Gao, Ning, Ye, Keqiong, Dong, MengQiu, Lei, Xiaoguang. Trifunctional cross-linker for mapping protein-protein interaction networks and comparing protein conformational states. ELIFE[J]. 2016, 5: https://doaj.org/article/d1b4dc53824b43dfb9c0301bb08e8ae7.
[22] Zeng, WenFeng, Liu, MingQi, Zhang, Yang, Wu, JianQiang, Fang, Pan, Peng, Chao, Nie, Aiying, Yan, Guoquan, Cao, Weiqian, Liu, Chao, Chi, Hao, Sun, RuiXiang, Wong, Catherine C L, He, SiMin, Yang, Pengyuan. pGlyco: a pipeline for the identification of intact N-glycopeptides by using HCD-and CID-MS/MS and MS3. SCIENTIFIC REPORTS[J]. 2016, 6: https://www.webofscience.com/wos/woscc/full-record/WOS:000375290500001.
[23] Ding, YueHe, Fan, ShengBo, Li, Shuang, Feng, BoYa, Gao, Ning, Ye, Keqiong, He, SiMin, Dong, MengQiu. Increasing the Depth of Mass-Spectrometry-Based Structural Analysis of Protein Complexes through the Use of Multiple Cross-Linkers. ANALYTICAL CHEMISTRY[J]. 2016, 88(8): 4461-4469, https://www.webofscience.com/wos/woscc/full-record/WOS:000374706000041.
[24] Sun, RuiXiang, Luo, Lan, Wu, Long, Wang, RuiMin, Zeng, WenFeng, Chi, Hao, Liu, Chao, He, SiMin. pTop 1.0: A High-Accuracy and High-Efficiency Search Engine for Intact Protein Identification. ANALYTICAL CHEMISTRY[J]. 2016, 88(6): 3082-3090, https://www.webofscience.com/wos/woscc/full-record/WOS:000372391500016.
[25] Zeng WenFeng, Zhang Yang, Liu MingQi, Wu JianQiang, Zhang XiaoJin, Yang Hao, Liu Chao, Chi Hao, Zhang Kun, Sun RuiXiang, Yang PengYuan, He SiMin. Trends in Mass Spectrometry-Based Large-scale N-Glycopeptides Analysis. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS[J]. 2016, 43(6): 550-562, https://www.webofscience.com/wos/woscc/full-record/WOS:000378458700002.
[26] Gao, Zhiqi, Wang, Zhiqiang, Zhang, Kun, Li, Yanchang, Zhang, Tao, Wang, Dongshu, Liu, Xiankai, Feng, Erling, Chang, Lei, Xu, Junjie, He, Simin, Xu, Ping, Zhu, Li, Wang, Hengliang. Experimental Validation of Bacillus anthracis A16R Proteogenomics. SCIENTIFIC REPORTS[J]. 2015, 5: https://www.webofscience.com/wos/woscc/full-record/WOS:000362082600001.
[27] Chi, Hao, He, Kun, Yang, Bing, Chen, Zhen, Sun, RuiXiang, Fan, ShengBo, Zhang, Kun, Liu, Chao, Yuan, ZuoFei, Wang, QuanHui, Liu, SiQi, Dong, MengQiu, He, SiMin. pFind-Alioth: A novel unrestricted database search algorithm to improve the interpretation of high-resolution MS/MS data (Reprinted from vol 125, pg 89-97, 2015). JOURNAL OF PROTEOMICS[J]. 2015, 129: 33-41, https://www.webofscience.com/wos/woscc/full-record/WOS:000364887600005.
[28] Zhang, Kun, Fu, Yan, Zeng, WenFeng, He, Kun, Chi, Hao, Liu, Chao, Li, YanChang, Gao, Yuan, Xu, Ping, He, SiMin. A note on the false discovery rate of novel peptides in proteogenomics. BIOINFORMATICS[J]. 2015, 31(20): 3249-3253, https://www.webofscience.com/wos/woscc/full-record/WOS:000362846600002.
[29] Chi, Hao, He, Kun, Yang, Bing, Chen, Zhen, Sun, RuiXiang, Fan, ShengBo, Zhang, Kun, Liu, Chao, Yuan, ZuoFei, Wang, QuanHui, Liu, SiQi, Dong, MengQiu, He, SiMin. pFind-Alioth: A novel unrestricted database search algorithm to improve the interpretation of high-resolution MS/MS data. JOURNAL OF PROTEOMICS[J]. 2015, 125: 89-97, http://dx.doi.org/10.1016/j.jprot.2015.05.009.
[30] Lu, Shan, Fan, ShengBo, Yang, Bing, Li, YuXin, Meng, JiaMing, Wu, Long, Li, Pin, Zhang, Kun, Zhang, MeiJun, Fu, Yan, Luo, Jincai, Sun, RuiXiang, He, SiMin, Dong, MengQiu. Mapping native disulfide bonds at a proteome scale. NATURE METHODS[J]. 2015, 12(4): 329-U73, http://dx.doi.org/10.1038/NMETH.3283.
[31] Liu, Chao, Song, ChunQing, Yuan, ZuoFei, Fu, Yan, Chi, Hao, Wang, LeHeng, Fan, ShengBo, Zhang, Kun, Zeng, WenFeng, He, SiMin, Dong, MengQiu, Sun, RuiXiang. pQuant Improves Quantitation by Keeping out Interfering Signals and Evaluating the Accuracy of Calculated Ratios. ANALYTICAL CHEMISTRY[J]. 2014, 86(11): 5286-5294, https://www.webofscience.com/wos/woscc/full-record/WOS:000336953100015.
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[36] Yuan ZuoFei, Wu Long, Liu Chao, Chi Hao, Fan ShengBo, Zhang Kun, Zeng WenFeng, Sun RuiXiang, He SiMin. Accurate Determination of Precursor Ions for Peptides in Large-scale Protein Identification. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS[J]. 2013, 40(1): 80-92, https://www.webofscience.com/wos/woscc/full-record/WOS:000314003100012.
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[39] Zhao, Yanmei, Sun, Wei, Zhang, Pan, Chi, Hao, Zhang, MeiJun, Song, ChunQing, Ma, Xuan, Shang, Yunlong, Wang, Bin, Hu, Youqiao, Hao, Zhiqi, Huehmer, Andreas F, Meng, Fanxia, LHernault, Steven W, He, SiMin, Dong, MengQiu, Miao, Long. Nematode sperm maturation triggered by protease involves sperm-secreted serine protease inhibitor (Serpin). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2012, 109(5): 1542-1547, http://www.irgrid.ac.cn/handle/1471x/756868.
[40] Fu, Yan, Xiu, LiYun, Jia, Wei, Ye, Ding, Sun, RuiXiang, Qian, XiaoHong, He, SiMin. DeltAMT: A Statistical Algorithm for Fast Detection of Protein Modifications From LC-MS/MS Data. MOLECULAR & CELLULAR PROTEOMICS[J]. 2011, 10(5): http://dx.doi.org/10.1074/mcp.M110.000455.
[41] Sun RuiXiang, Dong MengQiu, Chi Hao, Yang Bing, Xiu LiYun, Wang LeHeng, Fu Yan, He SiMin. ECD/ETD-based Tandem Mass Spectrometry in Proteomics. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS[J]. 2010, 37(1): 94-102, https://www.webofscience.com/wos/woscc/full-record/WOS:000273981400014.
[42] 孙瑞祥, 董梦秋, 迟浩, 杨兵, 秀丽蕴, 王乐珩, 付岩, 贺思敏. 基于电子捕获裂解/电子转运裂解串联质谱技术的蛋白质组学研究. 生物化学与生物物理进展[J]. 2010, 94-102, http://lib.cqvip.com/Qikan/Article/Detail?id=1001273964.
[43] Sun, RuiXiang, Dong, MengQiu, Song, ChunQing, Chi, Hao, Yang, Bing, Xiu, LiYun, Tao, Li, Jing, ZiuYi, Liu, Chao, Wang, LeHeng, Fu, Yan, He, SiMin. Improved Peptide Identification for Proteomic Analysis Based on Comprehensive Characterization of Electron Transfer Dissociation Spectra. JOURNAL OF PROTEOME RESEARCH[J]. 2010, 9(12): 6354-6367, https://www.webofscience.com/wos/woscc/full-record/WOS:000284856200024.
[44] Ye, Ding, Fu, Yan, Sun, RuiXiang, Wang, HaiPeng, Yuan, ZuoFei, Chi, Hao, He, SiMin. Open MS/MS spectral library search to identify unanticipated post-translational modifications and increase spectral identification rate. BIOINFORMATICS[J]. 2010, 26(12): i399-i406, http://www.corc.org.cn/handle/1471x/2410669.
[45] Zhou, Chen, Chi, Hao, Wang, LeHeng, Li, You, Wu, YanJie, Fu, Yan, Sun, RuiXiang, He, SiMin. Speeding up tandem mass spectrometry-based database searching by longest common prefix. BMC BIOINFORMATICS[J]. 2010, 11(1): 577-577, http://www.corc.org.cn/handle/1471x/2408973.
[46] Wang, Leheng, Wang, Wenping, Chi, Hao, Wu, Yanjie, Li, You, Fu, Yan, Zhou, Chen, Sun, Ruixiang, Wang, Haipeng, Liu, Chao, Yuan, Zuofei, Xiu, Liyun, He, SiMin. An efficient parallelization of phosphorylated peptide and protein identification. RAPID COMMUNICATIONS IN MASS SPECTROMETRY[J]. 2010, 24(12): 1791-1798, http://www.corc.org.cn/handle/1471x/2406611.
[47] Song LiNa, Wang JingLan, Liu JinFeng, Lu Zhuang, Sui ShaoHui, Jia Wei, Yang Bing, Chi Hao, Wang LeHeng, He SiMin, Yu WenFeng, Meng LingYan, Chen Shuo, Peng Xu, Liang Yimin, Cai Yun, Qian XiaoHong. N-glycosylation proteome of endoplasmic reticulum in mouse liver by ConA affinity chromatography coupled with LTQ-FT mass spectrometry. SCIENCE CHINA-CHEMISTRY[J]. 2010, 53(4): 768-777, https://www.webofscience.com/wos/woscc/full-record/WOS:000278263400010.
[48] Chi, Hao, Sun, RuiXiang, Yang, Bing, Song, ChunQing, Wang, LeHeng, Liu, Chao, Fu, Yan, Yuan, ZuoFei, Wang, HaiPeng, He, SiMin, Dong, MengQiu. pNovo: De novo Peptide Sequencing and Identification Using HCD Spectra. JOURNAL OF PROTEOME RESEARCH[J]. 2010, 9(5): 2713-2724, http://www.corc.org.cn/handle/1471x/2406807.
[49] Li, You, Chi, Hao, Wang, LeHeng, Wang, HaiPeng, Fu, Yan, Yuan, ZuoFei, Li, SuJun, Liu, YanSheng, Sun, RuiXiang, Zeng, Rong, He, SiMin. Speeding up tandem mass spectrometry based database searching by peptide and spectrum indexing. RAPID COMMUNICATIONS IN MASS SPECTROMETRY[J]. 2010, 24(6): 807-814, https://www.webofscience.com/wos/woscc/full-record/WOS:000276111100014.
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（ 1 ） 面向数据库搜索的蛋白质组精准鉴定技术研究, 主持, 国家级, 2016-07--2021-06
（ 2 ） 计算蛋白质组学创新交叉团队, 主持, 部委级, 2016-01--2018-12
（ 3 ） 蛋白质组海量质谱数据的深度解析, 主持, 国家级, 2010-01--2014-08

已指导学生

郑强  硕士研究生  081203-计算机应用技术  

王一  硕士研究生  081203-计算机应用技术  

迟浩  博士研究生  081203-计算机应用技术  

王文平  硕士研究生  081201-计算机系统结构  

周郴  硕士研究生  081203-计算机应用技术  

吴妍洁  硕士研究生  081203-计算机应用技术  

刘超  博士研究生  081203-计算机应用技术  

陈海丰  硕士研究生  081203-计算机应用技术  

何昆  硕士研究生  081203-计算机应用技术  

邬龙  硕士研究生  081203-计算机应用技术  

张昆  博士研究生  081203-计算机应用技术  

樊盛博  博士研究生  081203-计算机应用技术  

曾文锋  博士研究生  081203-计算机应用技术  

杨皓  博士研究生  081203-计算机应用技术  

王钊伟  硕士研究生  081203-计算机应用技术  

张晓今  硕士研究生  081203-计算机应用技术  

涂慧君  硕士研究生  081203-计算机应用技术  

吴建强  硕士研究生  085212-软件工程  

方润乾  硕士研究生  081203-计算机应用技术  

徐心仪  硕士研究生  081203-计算机应用技术  

王曦  硕士研究生  081203-计算机应用技术  

陈镇霖  博士研究生  081203-计算机应用技术  

现指导学生

周文婧  博士研究生  081203-计算机应用技术  

谭永卿  硕士研究生  081202-计算机软件与理论  

李金洋  硕士研究生  081203-计算机应用技术  

毛鹏志  博士研究生  081203-计算机应用技术