功效物质代谢途径解析与合成生物学研究

功效物质形成的分子调控机理与技术研发

基因编辑与分子设计育种

中国科学院大学岗位教师、博士生导师，中国科学院广州教育基地优秀研究生导师，

欢迎具有生物信息学、代谢工程、合成生物学以及CRISPR基因编辑背景的研究生加入。

指导的多名博士后获批国家自然科学基金青年基金、博士后基金面上项目资助，多名研究生获得各种奖励如优秀毕业生、国家奖学金、朱李月华奖学金、中国科学院华南植物园青年学术论坛一等奖等。

实时更新内容请查阅科研之友网页：https://www.scholarmate.com/apps/p/ShaohuaZENG

ORCID: https://orcid.org/0000-0003-4018-7933

071010-生物化学与分子生物学
090200-园艺学
071007-遗传学

代谢途径解析与合成生物学
功效物质分子调控与技术研发
基因编辑与分子设计育种

2010-07--中国科学院华南植物园   助理研究员-副研究员-研究员
2005-09--2010-06   中科院武汉植物园   博士
2002-09--2005-07   华中农业大学   硕士
1998-09--2002-07   华中农业大学   学士

   

2010-07~现在, 中国科学院华南植物园, 助理研究员-副研究员-研究员

2021-01-01-今,Journal of Ethnopharmacology, Chinese Herbal Medicines，科学通报等期刊审稿人, 审稿人
2020-11-01-今,青海有机枸杞产业国家创新联盟专家组, 专家组成员
2020-01-01-今,Food Chemistry, Information Processing in Agriculture, Food Research International,Journal of Food and Agriculture Chemistry等期刊审稿人, 审稿人
2018-09-13-今,广州科普名师,
2016-12-30-今,Biotechnology Advances, Plant Biotechnology Journal, Plant Physiology, Molecular Horticulture, Horticulture Research, International Journal of Biological Macromolecules, Industrial Crops and Products,等期刊审稿人, 审稿人

植物次生代谢与调控
植物次生代谢调控

   

（1） Haplotype-resolved telomere-to-telomere genome of the jade vine (Strongylodon macrobotrys) provides novel insights into the turquoise flower coloration, Journal of Integrative Plant Biology, 2026, 第 11 作者  通讯作者
（2） GLKs directly regulate carotenoid biosynthesis via interacting with GBFs in plants, New Phytologist, 2025, 第 4 作者
（3） Genome-wide identification and analysis of autophagy-related (ATG) genes in Lycium ruthenicum Murray reveals their crucial roles in salt stress tolerance, Plant Science, 2025, 第 6 作者  通讯作者
（4） Biotechnology advances in natural food colorant acylated anthocyanin production, Food Frontiers, 2025, 第 1 作者  通讯作者
（5） AN2 revisited: the LrAN2.1 from black goji berry (Lycium ruthenicum) is not a homolog of petunia AN2, Horticulture Advances, 2025, 第 2 作者  通讯作者
（6） Overexpression of anthocyanin activator LrAN2 improving black goji berry (Lycium ruthenicum) tolerant to cadmium stress, Journal of Hazardous Materials, 2025, 第 9 作者  通讯作者
（7） Exogenous melatonin enhancing the accumulation of flavonoids and carotenoids in wolfberry fruit at cold storage, Food Research International, 2025, 第 11 作者  通讯作者
（8） 香蕉主要栽培类型的分类及其起源和演化的研究进展, Advances in Classification of Main Cultivated Bananas(Musa spp.)and the Origins and Domestication, 广东农业科学, 2024, 第 8 作者
（9） T2T genome assemblies of Fallopia multiflora (Heshouwu) and F. multiflora var. angulate, Scientific Data, 2024, 第 1 作者
（10） An ultra-dense linkage map identified quantitative trait loci corresponding to fruit quality- and size-related traits in red goji berry, Frontiers in Plant Science, 2024, 第 4 作者  通讯作者
（11） Multi-omics reveal the molecular basis of LrAN2 overexpression in black goji callus promoting the excessive accumulation of petanin, a promising food blue colorant, Food Frontiers, 2024, 第 6 作者  通讯作者
（12） Fruit development and ripening orchestrating the biosynthesis and regulation of Lycium barbarum polysaccharides in goji berry, International Journal of Biological Macromolecules, 2024, 第 1 作者  通讯作者
（13） The high-quality genome of Grona styracifolia uncover the genomic mechanism of high level of schaftoside, a promising drug candidate for treatment of COVID-19, Horticulture Research, 2024, 
（14） Preservation and innovation of goji berry germplasm resources, Medicinal Plant Biology, 2024, 第 2 作者
（15） Multi-omics reveal the molecular basis of LrAN2 overexpression in black goji callus promoting the excessive accumulation of petanin, a promising food blue coloran, Food Frontiers, 2024, 第 5 作者
（16） The high-quality genome of Grona styracifolia uncover the genomic mechanism of high level of schaftoside, a promising drug candidate for treatment of COVID-19, Horticulture Research, 2024, 第 1 作者
（17） Characterization of dicaffeoylspermidine derivatives related glucosyltransferases during fruit development of goji berry, Food Chemistry, 2024, 
（18） An efficient improved CRISPR mediated gene function analysis system established in Lycium ruthenicum Murr., Industrial Crops and Products, 2023, 第 4 作者  通讯作者
（19） Lycium RIN negatively modulate the biosynthesis of kukoamine A in hairy roots through decreasing thermospermine synthase expression, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 第 7 作者  通讯作者
（20） The health-promoting anthocyanin petanin in Lycium ruthenicum fruit: a promising natural colorant, Critical Reviews in Food Science and Nutrition, 2023, 第 1 作者  通讯作者
（21） Salt stress affects the fruit quality of Lycium ruthenicum Murr., INDUSTRIAL CROPS & PRODUCTS, 2023, 第 8 作者  通讯作者
（22） An efficient improved CRISPR mediated gene function analysis system established in Lycium ruthenicum Murr., INDUSTRIAL CROPS & PRODUCTS, 2023, 第 4 作者  通讯作者
（23） Integrated metabolomics and transcriptomics reveal flavonoids glycosylation difference in two Citrus peels, SCIENTIA HORTICULTURAE, 2022, 第 5 作者  通讯作者
（24） 贮藏温度对鲜枸杞类胡萝卜素和氨基酸的影响及调控机制, 科学通报, 2022, 第 4 作者
（25） Spatio transcriptome uncover novel insight into the Lycium ruthenicum seedling tolerant to salt stress, INDUSTRIAL CROPS & PRODUCTS, 2022, 第 8 作者  通讯作者
（26） Selection and validation of reference genes for RT-qPCR analysis in Desmodium styracifolium Merr, 3 BIOTECH, 2021, 第 6 作者  通讯作者
（27） Integrative Analysis of Transcriptome and Metabolome Reveals Salt Stress Orchestrating the Accumulation of Specialized Metabolites in Lycium barbarum L. Fruit, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 第 2 作者  通讯作者
（28） Integrative Analysis of Transcriptome and Metabolome Reveals Salt Stress Orchestrating the Accumulation of Specialized Metabolites in Lycium barbarum L. Fruit, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 第 2 作者  通讯作者
（29） Transcriptome and small RNAome facilitate to study schaftoside in Desmodium styracifolium Merr, INDUSTRIAL CROPS AND PRODUCTS, 2020, 第 6 作者  通讯作者
（30） Anthocyanin and spermidine derivative hexoses coordinately increase in the ripening fruit of Lycium ruthenicum, FOOD CHEMISTRY, 2020, 第 5 作者  通讯作者
（31） Variation of Kukoamine A (KuA) and B (KuB) contents and related meteorological factors for Cortex Lycii radicis of different areas, BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2020, 第 2 作者
（32） Comparative proteomic and ultrastructural analysis shed light on fruit pigmentation distinct in two Lycium species, INDUSTRIAL CROPS AND PRODUCTS, 2020, 第 1 作者  通讯作者
（33） Identification of fruit size associated quantitative trait loci featuring SLAF based high-density linkage map of goji berry ( Lycium spp.), BMC PLANT BIOLOGY, 2020, 第 4 作者
（34） Growth and physiological alterations related to root-specific gene function of LrERF061-OE in Glycyrrhiza uralensis Fisch. hairy root clones under cadmium stress, PLANT CELL TISSUE AND ORGAN CULTURE, 2020, 第 3 作者  通讯作者
（35） 植物顶端有限生长相关基因与基因编辑育种研究进展, Progress of Determinate Growth Genes and Gene Editing Breeding, 热带作物学报, 2019, 第 4 作者
（36） Comparative transcriptome analysis and simple sequence repeat marker development for two closely related Isodon species used as 'Xihuangcao' herbs, TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, 2019, 第 3 作者
（37） Construction of the first high-density genetic map and QTL mapping for photosynthetic traits in Lycium barbarum L., MOLECULAR BREEDING, 2019, 第 5 作者
（38） Ectopic expression of ORANGE promotes carotenoid accumulation and fruit development in tomato, PLANT BIOTECHNOLOGY JOURNAL, 2019, 第 4 作者
（39） Plant-specific transcription factor LrTCP4 enhances secondary metabolite biosynthesis in Lycium ruthenicum hairy roots, PLANT CELL, TISSUE AND ORGAN CULTURE, 2019, 第 2 作者  通讯作者
（40） Liu Y, Song Y, Zeng S, Patra B, Yuan L, Wang Y. (2018) Isolation and characterization of a salt stress-responsive betaine aldehyde dehydrogenase in Lycium ruthenicum Murr. Physiol Plant., Physiol Plant, 2018, 
（41） Interspecies Developmental Differences in Metabonomic Phenotypes of Lycium ruthenicum and L-barbarum Fruits, JOURNAL OF PROTEOME RESEARCH, 2018, 第 2 作者
（42） Isolation and characterization of a salt stress-responsive betaine aldehyde dehydrogenase in Lycium ruthenicum Murr, PHYSIOLOGIA PLANTARUM, 2018, 第 3 作者
（43） 药用植物淫羊藿的类黄酮代谢途径研究及可持续开发利用, 2018全国植物生物学大会论文集中国作物学会会议论文集, 2018, 第 4 作者
（44） Rapid radiations of both kiwifruit hybrid lineages and their parents shed light on a two-layer mode of species diversification, NEW PHYTOLOGIST, 2017, 第 10 作者
（45） Aging and/or tissue-specific regulation of patchoulol and pogostone in two Pogostemon cablin (Blanco) Benth. cultivars, PHYSIOLOGIA PLANTARUM, 2016, 第 5 作者  通讯作者
（46） Leaf-Like Sepals Induced by Ectopic Expression of a SHORT VEGETATIVE PHASE (SVP)-Like MADS-Box Gene from the Basal Eudicot Epimedium sagittatum, FRONTIERS IN PLANT SCIENCE, 2016, 第 2 作者
（47） 广藿香香叶醇合酶基因克隆及表达分析, Clone and Expression Analysis of Geraniol Synthase Gene in Pogostemon cablin, 西北植物学报, 2016, 第 2 作者
（48） Comparative Profiling of miRNAs and Target Gene Identification in Distant-Grafting between Tomato and Lycium (Goji Berry), FRONTIERS IN PLANT SCIENCE, 2016, 第 5 作者
（49） Exploration of genetic diversity among medicinally important genus Epimedium species based on genomic and EST-SSR marker, NATURAL PRODUCT RESEARCH, 2015, 第 4 作者
（50） Elucidating the biosynthetic and regulatory mechanisms of flavonoid-derived bioactive components in Epimedium sagittatum, FRONTIERS IN PLANT SCIENCE, 2015, 第 2 作者
（51） SYSTEMATIC VALIDATION OF MEDICINALLY IMPORTANT GENUS EPIMEDIUM SPECIES BASED ON MICROSATELLITE MARKERS, PAKISTAN JOURNAL OF BOTANY, 2015, 第 4 作者
（52） 黑果枸杞和宁夏枸杞FT（Flowering Locus T）基因的克隆及表达分析, 基因组学与应用生物学, 2015, 第 2 作者
（53） Characterization of genes coding phenylalanine ammonia lyase and chalcone synthase in four Pogostemon cablin cultivars, BIOLOGIA PLANTARUM, 2015, 
（54） Identification and characterization of miRNAs in ripening fruit of Lycium barbarum L. using high-throughput sequencing, FRONTIERS IN PLANT SCIENCE, 2015, 第 1 作者  通讯作者
（55） Gene Expression Profiling of Development and Anthocyanin Accumulation in Kiwifruit ( Actinidia chinensis ) Based on Transcriptome Sequencing, PLOS ONE, 2015, 第 3 作者
（56） 宁夏枸杞苯丙氨酸解氨酶基因的cDNA克隆及其表达分析, Cloning and Expression Analysis of Phenylalanine Ammonia-lyase Gene from Lycium barbarum L., 热带亚热带植物学报, 2014, 第 3 作者
（57） 黑果枸杞和宁夏枸杞中黄酮醇合酶基因的克隆及表达分析, Molecular Cloning and Expression Analysis of Flavonol Synthase in Lycium ruthenicum Murr. and Lycium barbarum L., 基因组学与应用生物学, 2014, 第 4 作者
（58） Comparative analysis of anthocyanin biosynthesis during fruit development in two Lycium species, PHYSIOLOGIA PLANTARUM, 2014, 第 1 作者
（59） Virus-induced gene silencing in two novel functional plants, Lycium barbarum L. and Lycium ruthenicum Murr, SCIENTIA HORTICULTURAE, 2014, 第 3 作者
（60） Identification and Validation of Reference Genes for Quantitative Real-Time PCR Normalization and Its Applications in Lycium, PLOS ONE, 2014, 第 1 作者
（61） 黑果枸杞原花青素合成相关无色花色素还原酶基因和花青素还原酶基因的克隆及表达分析, JOURNAL OF CHINESE PHARMACEUTICAL SCIENCES, 2014, 第 2 作者
（62） 黑果枸杞原花青素合成相关无色花色素还原酶基因和花青素还原酶基因的克隆及表达分析（英文）, JOURNAL OF CHINESE PHARMACEUTICAL SCIENCES, 2014, 第 2 作者
（63） Comparative analysis of carotenoid accumulation in two goji (Lycium barbarum L. and L. ruthenicumMurr.) fruits, BMC PLANT BIOLOGY, 2014, 第 2 作者
（64） 广藿香八氢番茄红素脱氢酶PcPDS1基因克隆和序列分析, 中草药, 2013, 第 3 作者
（65） 广藿香八氢番茄红素合成酶PcPSY1基因克隆和序列分析, Cloning and sequential analysis of phytoene synthase (PcPSY1) gene in Pogostmen cablin, 广西植物, 2013, 第 4 作者
（66） Isolation and molecular characterization of thirteen R2R3-MYB transcription factors from Epimedium sagittatum., International Journal of Molecular Sciences, 2013, 第 1 作者
（67） The first view on the huge genome of Epimedium sagittatum (Sieb. et Zucc) Maxim, a Chinese traditional medicinal plant, International Journal of Molecular Sciences, 2013, 
（68） Cloning and characterization of phenylalanine ammonia-lyase in medicinal Epimedium species, PLANT CELL TISSUE AND ORGAN CULTURE, 2013, 第 1 作者
（69） First Insights into the Large Genome of Epimedium sagittatum (Sieb. et Zucc) Maxim, a Chinese Traditional Medicinal Plant, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2013, 第 2 作者
（70） Light stress suppresses the accumulation of epimedins A, B, C, and icariin in Epimedium, a traditional medicinal plant, ACTA PHYSIOLOGIAE PLANTARUM, 2013, 第 1 作者
（71） Integrated transcriptional and phytochemical analyses of the flavonoid biosynthesis pathway in Epimedium, PLANT CELL TISSUE AND ORGAN CULTURE, 2013, 第 1 作者
（72） A R2R3-MYB Transcription Factor from Epimedium sagittatum Regulates the Flavonoid Biosynthetic Pathway, PLOS ONE, 2013, 第 5 作者
（73） Isolation and characterization of two MADS-box genes from Lycium barbarum L., Biol Plantarum, 2011, 第 1 作者
（74） 淫羊藿属植物查耳酮合成酶启动子序列的克隆及比较分析, Cloning and Comparative Analysis of Promoters of Chalcone Synthase Gene inEpimediumL., 热带亚热带植物学报, 2011, 第 2 作者
（75） Development of an EST dataset and characterization of EST-SSRs in a traditional Chinese medicinal plant, Epimedium sagittatum (Sieb.EtZucc.) Maxim., BMC Genomics, 2010, 第 1 作者
（76） Genetics and Genomics of Chinese Medicinal Plants Epimedium L., HORTSCIENCE, 2010, 第 1 作者
（77） Development of a EST dataset and characterization of EST-SSRs in a traditional Chinese medicinal plant, Epimedium sagittatum (Sieb. Et Zucc.) Maxim, BMC GENOMICS, 2010, 第 1 作者
（78） 植物基因富集研究进展, Advances of gene enrichment in plant genome, 遗传, 2009, 第 1 作者
（79） Isolation and characterization of polymorphic microsatellite markers in the endangered Nothotsuga longibracteata (Pinaceae), MOLECULAR ECOLOGY NOTES, 2007, 第 4 作者
（80） In vitro induction, regeneration and analysis of autotetraploids derived from protoplasts and callus treated with colchicine in Citrus, PLANT CELL TISSUE AND ORGAN CULTURE, 2006, 第 1 作者
（81） 澳洲指橘与粗柠檬体细胞杂种倍性FCM分析及其花粉活力检测, Flow Cytometric Analysis of Ploidy and Pollen Viability Investigation of Somatic Hybrids Between Microcitrus papuana and Rough Lemon, 果树学报, 2003, 第 2 作者

（1） 枸杞属植物的化学与遗传多样性, Chemical and genetic diversity of wolfberry, Springer Netherlands, 2015-04, 第 4 作者

已指导学生

房路遥  硕士研究生  071010-生物化学与分子生物学  

黄金涛  硕士研究生  071010-生物化学与分子生物学  

林爽  博士研究生  071010-生物化学与分子生物学  

莫素祺  硕士研究生  071010-生物化学与分子生物学  

艾培炎  博士研究生  071010-生物化学与分子生物学  

阿彪  硕士研究生  071010-生物化学与分子生物学  

王志强  博士研究生  071010-生物化学与分子生物学  

贾一鑫  硕士研究生  086000-生物与医药  

魏瑾瑢  博士研究生  071010-生物化学与分子生物学  

韦国  硕士研究生  086000-生物与医药  

现指导学生

邹浩  硕士研究生  086000-生物与医药  

王晶  硕士研究生  086000-生物与医药