基本信息
高山  男  硕导  中国科学院海洋研究所
电子邮件: shangao@qdio.ac.cn
通信地址: 山东省青岛市市南区南海路7号
邮政编码:

研究领域

海洋硅藻生理生化与环境的互作,硅藻基因编辑

招生信息

   
招生专业
070703-海洋生物学
招生方向
生理、生化过程与调控

教育背景

2011-09--2014-06   中国科学院海洋研究所   博士
2008-09--2011-05   天津科技大学   硕士
2004-09--2008-06   苏州大学   学士
学历
博士研究生

学位
博士

工作经历

2014年7月-2016年12月 中国科学院海洋研究所 助理研究员

2017年1月-2018年11月 中国科学院海洋研究所 副研究员

2018年12月-至今      中国科学院海洋研究所 副研究员 硕士生导师

工作简历
2022-09~现在, 中国科学院海洋研究所, 副研究员一级
2019-01~2022-08,中国科学院海洋研究所, 副研究员二级
2017-01~2018-12,中国科学院海洋研究所, 副研究员三级
2014-07~2016-12,中国科学院海洋研究所, 助理研究员

专利与奖励

   
奖励信息
(1) 山东省海洋与渔业青年科技奖, , 省级, 2021
(2) 环式电子传递、磷酸戊糖途径和光呼吸在藻类抗逆中的协同作用, 三等奖, 市地级, 2018
(3) 藻类光合组成及其对环境(逆境)因子的响应, 二等奖, 部委级, 2016
(4) 中国科学院地奥奖学金, 一等奖, 院级, 2013
(5) 天津市优秀硕士论文, 省级, 2013
(6) 刘瑞玉海洋科学奖, , 院级, 2012
(7) 第二届中国藻类学研究优秀论文奖, 二等奖, 其他, 2011
专利成果
[1] 王广策, 高山, 杨文婷. 一种能胞外分泌抗菌肽的三角褐指藻构建方法. 202211379601.9, 2022-11-05.
[2] 王广策, 高山, 周璐. 一种转入外源基因来提高三角褐指藻藻种高温抗性的方法. 202210519510.4, 2022-05-13.

出版信息

   
发表论文
[1] Yang, Wenting, Zhou, Lu, Wang, Jing, Wang, Lijun, Gao, Shan, Wang, Guangce. Knockout of a diatom cryptochrome by CRISPR/Cas9 causes an increase in light-harvesting protein levels and accumulation of fucoxanthin. ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS[J]. 2022, 66: http://dx.doi.org/10.1016/j.algal.2022.102822.
[2] Zhou, Lu, Gao, Shan, Yang, Wenting, Wu, Songcui, Huan, Li, Xie, Xiujun, Wang, Xulei, Lin, Senjie, Wang, Guangce. Transcriptomic and metabolic signatures of diatom plasticity to light fluctuations. PLANT PHYSIOLOGY[J]. 2022, 190(4): 2295-2314, [3] Gao, Shan, Zhou, Lu, Yang, Wenting, Wang, Lijun, Liu, Xuehua, Gong, Yingchun, Hu, Qiang, Wang, Guangce. Overexpression of a novel gene (Pt2015) endows the commercial diatom Phaeodactylum tricornutum high lipid content and grazing resistance. BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS[J]. 2022, 15(1): http://dx.doi.org/10.1186/s13068-022-02221-y.
[4] Gao, Shan, Pinnola, Alberta, Zhou, Lu, Zheng, Zhenbing, Li, Zhuangyue, Bassi, Roberto, Wang, Guangce. Light-harvesting complex stress-related proteins play crucial roles in the acclimation of Physcomitrella patens under fluctuating light conditions. PHOTOSYNTHESIS RESEARCH[J]. 2021, [5] Zhou, Lu, Wu, Songcui, Gu, Wenhui, Wang, Lijun, Wang, Jing, Gao, Shan, Wang, Guangce. Photosynthesis acclimation under severely fluctuating light conditions allows faster growth of diatoms compared with dinoflagellates (vol 21, 164, 2021). BMC PLANT BIOLOGY. 2021, 21(1): http://dx.doi.org/10.1186/s12870-021-02984-w.
[6] Liu, Xuehua, Huan, Li, Gu, Wenhui, Gao, Shan, Zheng, Zhenbing, Wang, Guangce. Acid treatment combined with high light leads to increased removal efficiency of Ulva prolifera. ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS[J]. 2020, 45: http://dx.doi.org/10.1016/j.algal.2019.101745.
[7] 王广策, 王辉, 高山, 郇丽, 王旭雷, 顾文辉, 解修俊, 张建恒, 孙松, 于仁成, 何培民, 郑阵兵, 林阿朋, 牛建峰, 王立军, 张宝玉, 沈颂东, 卢山. 绿潮生物学机制研究. 海洋与湖沼[J]. 2020, 51(4): 789-808, http://lib.cqvip.com/Qikan/Article/Detail?id=7102346652.
[8] Zhou, Lu, Gao, Shan, Wu, Songcui, Han, Danxiang, Wang, Hui, Gu, Wenhui, Hu, Qiang, Wang, Jing, Wang, Guangce. PGRL1 overexpression inPhaeodactylum tricornutuminhibits growth and reduces apparent PSII activity. PLANT JOURNAL[J]. 2020, 103(5): 1850-1857, https://www.webofscience.com/wos/woscc/full-record/WOS:000544771900001.
[9] Gao, Shan, Zheng, Zhenbing, Wang, Jing, Wang, Guangce. Slow zeaxanthin accumulation and the enhancement of CP26 collectively contribute to an atypical non-photochemical quenching in macroalga Ulva prolifera under high light. JOURNAL OF PHYCOLOGY[J]. 2020, 56(2): 393-403, https://www.webofscience.com/wos/woscc/full-record/WOS:000507129100001.
[10] Zhou, Lu, Gao, Shan, Huan, Li, Wu, Songcui, Wang, Guangce, Gu, Wenhui. Enzyme activities suggest that the NAD-ME C4 type CCM exist in Ulva sp.. ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS[J]. 2020, 47: http://dx.doi.org/10.1016/j.algal.2020.101809.
[11] Zheng, Zhenbing, Gao, Shan, Wang, Guangce. High salt stress in the upper part of floating mats of Ulva prolifera, a species that causes green tides, enhances non-photochemical quenching. JOURNAL OF PHYCOLOGY[J]. 2019, 55(5): 1041-1049, http://ir.qdio.ac.cn/handle/337002/162759, http://www.irgrid.ac.cn/handle/1471x/6861234, http://ir.qdio.ac.cn/handle/337002/162760, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000483141100001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=3a85505900f77cc629623c3f2907beab.
[12] Shan Gao, Zhen Chi, Hailong Chen, Zhenbing Zheng, Yuxiang Weng, Guangce Wang. A Supercomplex, of Approximately 720 kDa and Composed of Both Photosystem Reaction Centers, Dissipates Excess Energy by PSI in Green Macroalgae Under Salt Stress. PLANT & CELL PHYSIOLOGY. 2019, 60(1): http://kns.cnki.net/KCMS/detail/detail.aspx?QueryID=0&CurRec=1&recid=&FileName=SJOXAFA2426F2677B2851A4DEF191B94C692&DbName=WWMERGEJ03&DbCode=WWME&yx=&pr=&URLID=&bsm=.
[13] Zheng, Zhenbing, Gao, Shan, Wang, Guangce. Far red light induces the expression of LHCSR to trigger nonphotochemical quenching in the intertidal green macroalgae Ulva prolifera. ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS[J]. 2019, 40: 101512-, http://dx.doi.org/10.1016/j.algal.2019.101512.
[14] Gao, Shan, Chi, Zhen, Chen, Hailong, Zheng, Zhenbing, Weng, Yuxiang, Wang, Guangce. A Supercomplex, of Approximately 720 kDa and Composed of Both Photosystem Reaction Centers, Dissipates Excess Energy by PSI in Green Macroalgae Under Salt Stress. PLANT AND CELL PHYSIOLOGY[J]. 2019, 60(1): 166-175, http://ir.qdio.ac.cn/handle/337002/155581.
[15] Huan, Li, Wang, Chao, Gao, Shan, He, Linwen, Lu, Xiaoping, Wang, Xulei, Liu, Xuehua, Wang, Guangce. Preliminary comparison of atmospheric CO2 enhancement to photosynthesis of Pyropia yezoensis (Bangiales, Rhodophyta) leafy thalli and filamentous thalli. PHYCOLOGICAL RESEARCH[J]. 2018, 66(2): 117-126, https://www.webofscience.com/wos/woscc/full-record/WOS:000428890000004.
[16] Huan, Li, Su, Haixia, Duan, Chenxue, Gao, Shan, Xie, Xiujun, Wang, Guangce. Ulva prolifera (Chlorophyta): a suitable material to remove Cd2+ from aquatic environments. WATER AND ENVIRONMENT JOURNAL[J]. 2018, 32(1): 26-33, http://ir.qdio.ac.cn/handle/337002/154356.
[17] 郑阵兵, 高山, 王广策. 2017年绿潮浒苔(Ulva prolifera)生理特征及孢子囊形成情况分析. 海洋与湖沼[J]. 2018, 49(5): 999-1005, http://lib.cqvip.com/Qikan/Article/Detail?id=7000863845.
[18] Zheng, Zhenbing, Gao, Shan, Huan, Li, Wang, GuangCe. Diluted seawater affects phytohormone receptors and maintains the protonema stage in Physcomitrella patens. PLANT JOURNAL[J]. 2018, 93(1): 119-130, https://www.webofscience.com/wos/woscc/full-record/WOS:000418228000010.
[19] Yu, Bin, Niu, Jianfeng, Feng, Jianhua, Xu, Meiling, Xie, Xiujun, Gu, Wenhui, Gao, Shan, Wang, Guangce. Regulation of Ferredoxin-NADP(+) Oxidoreductase to Cyclic Electron Transport in High Salinity Stressed Pyropia yezoensis. FRONTIERS IN PLANT SCIENCE[J]. 2018, 9: http://ir.qdio.ac.cn/handle/337002/163501, http://www.irgrid.ac.cn/handle/1471x/6861270, http://ir.qdio.ac.cn/handle/337002/163502, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000439717600001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=3a85505900f77cc629623c3f2907beab.
[20] Zheng Zhenbing, Gao Shan, He Yuan, Li Zhuangyue, Li Yuanxiang, Cai Xuehua, Gu Whenhui, Wang Guangce. The enhancement of the oxidative pentose phosphate pathway maybe involved in resolving imbalance between photosystem I and II in Dunaliella salina. ALGAL RESEARCH[J]. 2017, [21] Zheng, Zhenbing, Gao, Shan, He, Yuan, Li, Zhuangyue, Li, Yuanxiang, Cai, Xuehua, Gu, Whenhui, Wang, Guangce. The enhancement of the oxidative pentose phosphate pathway maybe involved in resolving imbalance between photosystem I and II in Dunaliella salina. ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS[J]. 2017, 26: 402-408, http://ir.qdio.ac.cn/handle/337002/143213.
[22] Zheng Zhenbing, Gao Shan, Huan Li, Wang GuangCe. Diluted seawater affects phytohormone receptors and maintains the protonema stage in Physcomitrella patens. THE PLANT JOURNAL. 2017, [23] 王广策, 唐学玺, 何培民, 孙松, 高山, 郇丽, 王辉. 浒苔光合作用等关键生理过程对环境因子响应途径的研究进展. 植物生理学报[J]. 2016, 52(11): 1627-1636, http://lib.cqvip.com/Qikan/Article/Detail?id=670808468.
[24] Gao, Shan, Zheng, Zhenbing, Huan, Li, Wang, Guangce. G6PDH activity highlights the operation of the cyclic electron flow around PSI in Physcomitrella patens during salt stress. SCIENTIFIC REPORTS[J]. 2016, 6: https://www.webofscience.com/wos/woscc/full-record/WOS:000370368000001.
[25] Wang, Hui, Lin, Apeng, Gu, Wenhui, Huan, Li, Gao, Shan, Wang, Guangce. The sporulation of the green alga Ulva prolifera is controlled by changes in photosynthetic electron transport chain. SCIENTIFIC REPORTS[J]. 2016, 6: https://www.webofscience.com/wos/woscc/full-record/WOS:000374536400002.
[26] 高山. Photosynthetic performance responses to saline stress by the low intertidal macroalga, Sargassum fusiforme (Sargassaceae). Photosynthetica. 2016, [27] Lu, Xiaoping, Huan, Li, Gao, Shan, He, Linwen, Wang, Guangce. NADPH from the oxidative pentose phosphate pathway drives the operation of cyclic electron flow around photosystem I in high-intertidal macroalgae under severe salt stress. PHYSIOLOGIA PLANTARUM[J]. 2016, 156(4): 397-406, https://www.webofscience.com/wos/woscc/full-record/WOS:000372974400003.
[28] 王广策, 唐学玺, 何培民, 孙松, 高山, 郇丽, 王辉. 浒苔光合作用等关键生理过程对环境因子响应途径的研究进展简. 植物生理学报[J]. 2016, 1627-1636, http://lib.cqvip.com/Qikan/Article/Detail?id=90878376504849544949484948.
[29] Gao, Shan, Sun, Qinghai, Tao, Yueliang, Wang, Xulei, Li, Wei, Huan, Li, Wu, Mingjiang, Wang, Guangce. A decline in macro-algae species resulting in the overwhelming prevalence of Corallina species is caused by low-pH seawater induced by short-term acid rain. JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY[J]. 2016, 475: 144-153, http://dx.doi.org/10.1016/j.jembe.2015.11.019.
[30] Gao, Shan, Gu, Wenhui, Xiong, Qian, Ge, Feng, Xie, Xiujun, Li, Jian, Chen, Weizhou, Pan, Guanghua, Wang, Guangce. Desiccation enhances phosphorylation of PSII and affects the distribution of protein complexes in the thylakoid membrane. PHYSIOLOGIA PLANTARUM[J]. 2015, 153(3): 492-502, http://www.irgrid.ac.cn/handle/1471x/978686.
[31] Zhao, Peipei, Gu, Wenhui, Wu, Songcui, Huang, Aiyou, He, Linwen, Xie, Xiujun, Gao, Shan, Zhang, Baoyu, Niu, Jianfeng, Lin, A Peng, Wang, Guangce. Silicon enhances the growth of Phaeodactylum tricornutum Bohlin under green light and low temperature. SCIENTIFIC REPORTS[J]. 2014, 4: https://www.webofscience.com/wos/woscc/full-record/WOS:000331217500002.
[32] Gao, Shan, Zheng, Zhenbing, Gu, Wenhui, Xie, Xiujun, Huan, Li, Pan, Guanghua, Wang, Guangce. Photosystem I shows a higher tolerance to sorbitol-induced osmotic stress than photosystem II in the intertidal macro-algae Ulva prolifera (Chlorophyta). PHYSIOLOGIA PLANTARUM[J]. 2014, 152(2): 380-388, https://www.webofscience.com/wos/woscc/full-record/WOS:000342318600014.
[33] Gu, Wenhui, Li, Huan, Zhao, Peipei, Yu, Ruixue, Pan, Guanghua, Gao, Shan, Xie, Xiujun, Huang, Aiyou, He, Linwen, Wang, Guangce. Quantitative proteomic analysis of thylakoid from two microalgae (Haematococcus pluvialis and Dunaliella salina) reveals two different high light-responsive strategies. SCIENTIFIC REPORTS[J]. 2014, 4: https://www.webofscience.com/wos/woscc/full-record/WOS:000343589400002.
[34] 周伟, 何林文, 陆勤勤, 朱建一, 高山, 杨睿灵, 杨芳, 王广策. 条斑紫菜类囊体膜蛋白质组双向电泳研究方法. 海洋科学[J]. 2014, 38(3): 63-68,  http://dx.doi.org/10.11759/hykx20130131002.
[35] Huan, Li, Xie, Xiujun, Zheng, Zhenbing, Sun, Feifei, Wu, Songcui, Li, Moyang, Gao, Shan, Gu, Wenhui, Wang, Guangce. Positive Correlation Between PSI Response and Oxidative Pentose Phosphate Pathway Activity During Salt Stress in an Intertidal Macroalga. PLANT AND CELL PHYSIOLOGY[J]. 2014, 55(8): 1395-1403, https://www.webofscience.com/wos/woscc/full-record/WOS:000342978000003.
[36] Xie, Xiujun, Gu, Wenhui, Gao, Shan, Lu, Shan, Li, Jian, Pan, Guanghua, Wang, Guangce, Shen, Songdong. Alternative Electron Transports Participate in the Maintenance of Violaxanthin De-Epoxidase Activity of Ulva sp under Low Irradiance. PLOS ONE[J]. 2013, 8(11): https://doaj.org/article/58c9d8dc4280464bbba0ad1c49617984.
[37] Gao, Shan, Niu, Jianfeng, Chen, Weizhou, Wang, Guangce, Xie, Xiujun, Pan, Guanghua, Gu, Wenhui, Zhu, Daling. The physiological links of the increased photosystem II activity in moderately desiccated Porphyra haitanensis (Bangiales, Rhodophyta) to the cyclic electron flow during desiccation and re-hydration. PHOTOSYNTHESIS RESEARCH[J]. 2013, 116(1): 45-54, http://dx.doi.org/10.1007/s11120-013-9892-4.
[38] Gu, Wenhui, Xie, Xiujun, Gao, Shan, Zhou, Wei, Pan, Guanghua, Wang, Guangce. Comparison of Different Cells of Haematococcus pluvialis Reveals an Extensive Acclimation Mechanism during its Aging Process: From a Perspective of Photosynthesis. PLOS ONE[J]. 2013, 8(7): https://doaj.org/article/916b53a04f3b48729596f0a06f6d9ef9.
[39] Xie, Xiujun, Gao, Shan, Gu, Wenhui, Pan, Guanghua, Wang, Guangce. Desiccation Induces Accumulations of Antheraxanthin and Zeaxanthin in Intertidal Macro-Alga Ulva pertusa (Chlorophyta). PLOS ONE[J]. 2013, 8(9): https://doaj.org/article/3047c67c751b46c1b604ea1539f4b6ea.
[40] Gao, Shan, Wang, Guangce. The enhancement of cyclic electron flow around photosystem I improves the recovery of severely desiccated Porphyra yezoensis (Bangiales, Rhodophyta). JOURNAL OF EXPERIMENTAL BOTANY[J]. 2012, 63(12): 4349-4358, http://dx.doi.org/10.1093/jxb/ers082.
[41] Gao, Shan, Wang, Guangce, Yang, Ruiling, Xie, Xiujun, Pan, Guanghua, Xu, Pu, Zhu, Jianyi. VARIATIONS IN THE CELL WALLS AND PHOTOSYNTHETIC PROPERTIES OF PORPHYRA YEZOENSIS (BANGIALES, RHODOPHYTA) DURING ARCHEOSPORE FORMATION. JOURNAL OF PHYCOLOGY[J]. 2011, 47(4): 839-845, https://www.webofscience.com/wos/woscc/full-record/WOS:000293096000014.
[42] Gao, Shan, Shen, Songdong, Wang, Guangce, Niu, Jianfeng, Lin, Apeng, Pan, Guanghua. PSI-Driven Cyclic Electron Flow Allows Intertidal Macro-Algae Ulva sp (Chlorophyta) to Survive in Desiccated Conditions. PLANT AND CELL PHYSIOLOGY[J]. 2011, 52(5): 885-893, http://ir.qdio.ac.cn/handle/337002/11924.
[43] Gao, Shan, Chen, Xiaoyuan, Yi, Qianqian, Wang, Guangce, Pan, Guanghua, Lin, Apeng, Peng, Guang. A Strategy for the Proliferation of Ulva prolifera, Main Causative Species of Green Tides, with Formation of Sporangia by Fragmentation. PLOS ONE[J]. 2010, 5(1): http://www.corc.org.cn/handle/1471x/2405783.
[44] Wenting Yang, Lu Zhou, Jing Wang, Lijun Wang, Shan Gao, Guangce Wang. Knockout of a diatom cryptochrome by CRISPR/Cas9 causes an increase in light-harvesting protein levels and accumulation of fucoxanthin. ALGAL RESEARCH. http://dx.doi.org/10.1016/j.algal.2022.102822.

科研活动

   
科研项目
( 1 ) 浒苔叶绿体NAD(P)H脱氢酶的组成、分布及其介导的环式电子传递对失水胁迫的响应, 负责人, 国家任务, 2016-01--2019-12
( 2 ) 浒苔类囊体结构和PSI、PSII等膜蛋白复合体对失水胁迫的响应机制, 负责人, 国家任务, 2020-01--2023-12
( 3 ) 浒苔光合生理的分子基础及其对逆境的响应机制, 负责人, 研究所自选, 2018-07--2021-06

指导学生

现指导学生

李鑫  硕士研究生  070703-海洋生物学