基本信息
饶子和 男 博导 中国科学院生物物理研究所
电子邮件： raozh@nankai.edu.cn
通信地址： 北京市朝阳区大屯路15号
邮政编码：
电子邮件： raozh@nankai.edu.cn
通信地址： 北京市朝阳区大屯路15号
邮政编码：
招生信息
招生专业
071010-生物化学与分子生物学
招生方向
人类感染相关或具有重要生理功能的蛋白质与病毒的三维结构研究，以及创新药物治疗的开发
蛋白质结构、功能与创新药物
蛋白质结构、功能与创新药物
教育背景
1985-07--1989-07 澳大利亚墨尔本大学 博士
1979-07--1982-07 中国科学院生物物理研究所 硕士
1973-06--1977-06 中国科技大学 本科
1979-07--1982-07 中国科学院生物物理研究所 硕士
1973-06--1977-06 中国科技大学 本科
工作经历
工作简历
2006-05~2011-01,南开大学, 校长
2003-03~2007-03,中国科学院生物物理研究所, 所长
1996-07~现在, 清华大学, 教授
1992-07~1996-07,牛津大学, 高级研究员
1989-07~1992-07,英国牛津大学, 博士后
1982-07~1985-07,中国科学院生物物理研究所, 助理研究员
1977-07~1979-07,中国科学院生物物理研究所, 助理研究员
2003-03~2007-03,中国科学院生物物理研究所, 所长
1996-07~现在, 清华大学, 教授
1992-07~1996-07,牛津大学, 高级研究员
1989-07~1992-07,英国牛津大学, 博士后
1982-07~1985-07,中国科学院生物物理研究所, 助理研究员
1977-07~1979-07,中国科学院生物物理研究所, 助理研究员
社会兼职
2013-12-31-2017-12-30,国际纯粹与应用生物物理联合会(IUPAB ), 主席
2010-01-01-今,Protein & Cell, 主编
2006-01-01-今,中国生物物理学会, 理事长
2010-01-01-今,Protein & Cell, 主编
2006-01-01-今,中国生物物理学会, 理事长
专利与奖励
奖励信息
（1） 杰出学术领袖奖, 特等奖, 国家级, 2009
（2） 谈家桢生命科学成就奖, 特等奖, 国家级, 2008
（3） 第三世界科学院最高奖-第里雅斯特科学奖, 特等奖, 其他, 2006
（4） 何梁何利奖, 一等奖, 国家级, 2003
（5） 长江学者特聘教授, 特等奖, 部委级, 2000
（6） 求是杰出青年学者奖, 一等奖, 国家级, 1999
（2） 谈家桢生命科学成就奖, 特等奖, 国家级, 2008
（3） 第三世界科学院最高奖-第里雅斯特科学奖, 特等奖, 其他, 2006
（4） 何梁何利奖, 一等奖, 国家级, 2003
（5） 长江学者特聘教授, 特等奖, 部委级, 2000
（6） 求是杰出青年学者奖, 一等奖, 国家级, 1999
出版信息
发表论文
[1] Jingyuan Cong, Xiaoying Feng, Huiling Kang, Wangjun Fu, Lei Wang, Chenlong Wang, Xuemei Li, Yutao Chen, Zihe Rao. Structure of the Newcastle Disease Virus L protein in complex with tetrameric phosphoprotein. NATURE COMMUNICATIONS[J]. 2023, 14(1): 1-11, https://doaj.org/article/7196b063cb1446b9816068ae67b3d122.
[2] Zhao, Yao, Fang, Chao, Zhang, Qi, Zhang, Ruxue, Zhao, Xiangbo, Duan, Yinkai, Wang, Haofeng, Zhu, Yan, Feng, Lu, Zhao, Jinyi, Shao, Maolin, Yang, Xiuna, Zhang, Leike, Peng, Chao, Yang, Kailin, Ma, Dawei, Rao, Zihe, Yang, Haitao. Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332. PROTEIN & CELLnull. 2022, 13(9): 689-693, http://lib.cqvip.com/Qikan/Article/Detail?id=7108250623.
[3] Wang, Chenlong, Kang, Huiling, Tan, Ming, Cong, Jingyuan, Su, Dan, Li, Xuemei, Chen, Yutao. Structural Insight into Terminal Galactose Recognition by Two Non-HBGA Binding GI.3 Noroviruses. JOURNAL OF VIROLOGY[J]. 2022, 96(13): http://dx.doi.org/10.1128/jvi.00420-22.
[4] Tang, Yanting, Mu, An, Zhang, Yuying, Zhou, Shan, Wang, Weiwei, Lai, Yuezheng, Zhou, Xiaoting, Liu, Fengjiang, Yang, Xiuna, Gong, Hongri, Wang, Quan, Rao, Zihe. Cryo-EM structure of Mycobacterium smegmatis DyP-loaded encapsulin. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2021, 118(16): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072242/.
[5] Weiwei Wang, Yan Gao, Yanting Tang, Xiaoting Zhou, Yuezheng Lai, Shan Zhou, Yuying Zhang, Xiuna Yang, Fengjiang Liu, Luke W Guddat, Quan Wang, Zihe Rao, Hongri Gong. Cryo-EM structure of mycobacterial cytochrome bd reveals two oxygen access channels. NATURE COMMUNICATIONS[J]. 2021, 12(1): http://dx.doi.org/10.1038/s41467-021-24924-w.
[6] Linhua Tai, Guoliang Zhu, Minnan Yang, Lei Cao, Xiaorui Xing, Guoliang Yin, Chun Chan, Chengfeng Qin, Zihe Rao, Xiangxi Wang, Fei Sun, Yun Zhu. Nanometer-resolution in situ structure of the SARS-CoV-2 postfusion spike protein. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2021, 118(48): [7] Huiling Kang, Jingyuan Cong, Chenlong Wang, Wenxin Ji, Yuhui Xin, Ying Qian, Xuemei Li, Yutao Chen, Zihe Rao. Structural basis for recognition and regulation of arenavirus polymerase L by Z protein. NATURE COMMUNICATIONS[J]. 2021, 12(1): http://dx.doi.org/10.1038/s41467-021-24458-1.
[8] Zhou, Xiaoting, Gao, Yan, Wang, Weiwei, Yang, Xiaolin, Yang, Xiuna, Liu, Fengjiang, Tang, Yanting, Lam, Sin Man, Shui, Guanghou, Yu, Lu, Tian, Changlin, Guddat, Luke W, Wang, Quan, Rao, Zihe, Gong, Hongri. Architecture of the mycobacterial succinate dehydrogenase with a membrane-embedded Rieske FeS cluster. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2021, 118(15): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054011/.
[9] Shan Zhou, Weiwei Wang, Xiaoting Zhou, Yuying Zhang, Yuezheng Lai, Yanting Tang, Jinxu Xu, Dongmei Li, Jianping Lin, Xiaolin Yang, Ting Ran, Hongming Chen, Luke W Guddat, Quan Wang, Yan Gao, Zihe Rao, Hongri Gong, David Drew, Volker Dtsch. Structure of Mycobacterium tuberculosis cytochrome bcc in complex with Q203 and TB47, two anti-TB drug candidates. ELIFE[J]. 2021, 10: http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA202112115573314ZK.
[10] Yang, Haitao, Rao, Zihe. Structural biology of SARS-CoV-2 and implications for therapeutic development. NATURE REVIEWS MICROBIOLOGYnull. 2021, 19(11): 685-700, http://dx.doi.org/10.1038/s41579-021-00630-8.
[11] Zhu, Ling, Deng, YongQiang, Zhang, RongRong, Cui, Zhen, Sun, ChunYun, Fan, ChangFa, Xing, Xiaorui, Huang, Weijin, Chen, Qi, Zhang, NaNa, Ye, Qing, Cao, TianShu, Wang, Nan, Wang, Lei, Cao, Lei, Wang, Huiyu, Kong, Desheng, Ma, Juan, Luo, Chunxia, Zhang, Yanjing, Nie, Jianhui, Sun, Yao, Lv, Zhe, Shaw, Neil, Li, Qianqian, Li, XiaoFeng, Hu, Junjie, Xie, Liangzhi, Rao, Zihe, Wang, Youchun, Wang, Xiangxi, Qin, ChengFeng. Double lock of a potent human therapeutic monoclonal antibody against SARS-CoV-2. NATIONAL SCIENCE REVIEW[J]. 2021, 8(3): 24-36, https://www.sciengine.com/doi/10.1093/nsr/nwaa297.
[12] Yan, Liming, Yang, Yunxiang, Li, Mingyu, Zhang, Ying, Zheng, Litao, Ge, Ji, Huang, Yucen C, Liu, Zhenyu, Wang, Tao, Gao, Shan, Zhang, Ran, Huang, Yuanyun Y, Guddat, Luke W, Gao, Yan, Rao, Zihe, Lou, Zhiyong. Coupling of N7-methyltransferase and 3 '-5 ' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading. CELL[J]. 2021, 184(13): 3474-+, http://dx.doi.org/10.1016/j.cell.2021.05.033.
[13] Wu, Jiqin, Wang, Haofeng, Liu, Qiaojie, Li, Rui, Gao, Yan, Fang, Xiang, Zhong, Yao, Wang, Meihua, Wang, Quan, Rao, Zihe, Gong, Peng. Remdesivir overcomes the S861 roadblock in SARS-CoV-2 polymerase elongation complex. CELL REPORTS[J]. 2021, 37(4): 109882-109882, http://dx.doi.org/10.1016/j.celrep.2021.109882.
[14] Fu, Dan, Zhang, Guangshun, Wang, Yuhui, Zhang, Zheng, Hu, Hengrui, Shen, Shu, Wu, Jun, Li, Bo, Li, Xin, Fang, Yaohui, Liu, Jia, Wang, Qiao, Zhou, Yunjiao, Wang, Wei, Li, Yufeng, Lu, Zhonghua, Wang, Xiaoxiao, Nie, Cui, Tian, Yujie, Chen, Da, Wang, Yuan, Zhou, Xingdong, Wang, Qisheng, Yu, Feng, Zhang, Chen, Deng, Changjing, Zhou, Liang, Guan, Guangkuo, Shao, Na, Lou, Zhiyong, Deng, Fei, Zhang, Hongkai, Chen, Xinwen, Wang, Manli, Liu, Louis, Rao, Zihe, Guo, Yu. Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes. PLOS BIOLOGY[J]. 2021, 19(5): http://dx.doi.org/10.1371/journal.pbio.3001209.
[15] Wang, Nan, Chen, Wenyuan, Zhu, Ling, Zhu, Dongjie, Feng, Rui, Wang, Jialing, Zhu, Bin, Zhang, Xinzheng, Chen, Xiaoqing, Liu, Xianjie, Yan, Runbin, Ni, Dongyao, Zhou, Grace Guoying, Liu, Hongrong, Rao, Zihe, Wang, Xiangxi. Structures of the portal vertex reveal essential protein-protein interactions for Herpesvirus assembly and maturation. PROTEIN & CELL[J]. 2020, 11(5): 366-373, http://lib.cqvip.com/Qikan/Article/Detail?id=7102116302.
[16] Gao, Yan, Yan, Liming, Huang, Yucen, Liu, Fengjiang, Zhao, Yao, Cao, Lin, Wang, Tao, Sun, Qianqian, Ming, Zhenhua, Zhang, Lianqi, Ge, Ji, Zheng, Litao, Zhang, Ying, Wang, Haofeng, Zhu, Yan, Zhu, Chen, Hu, Tianyu, Hua, Tian, Zhang, Bing, Yang, Xiuna, Li, Jun, Yang, Haitao, Liu, Zhijie, Xu, Wenqing, Guddat, Luke W, Wang, Quan, Lou, Zhiyong, Rao, Zihe. Structure of the RNA-dependent RNA polymerase from COVID-19 virus. SCIENCE[J]. 2020, 368(6492): 779-+, http://dx.doi.org/10.1126/science.abb7498.
[17] Wang, Lin, Wu, Juehui, Li, Jun, Yang, Hua, Tang, Tianqi, Liang, Haijiao, Zuo, Mianyong, Wang, Jie, Liu, Haipeng, Liu, Feng, Chen, Jianxia, Liu, Zhonghua, Wang, Yang, Peng, Cheng, Wu, Xiangyang, Zheng, Ruijuan, Huang, Xiaochen, Ran, Yajun, Rao, Zihe, Ge, Baoxue. Host-mediated ubiquitination of a mycobacterial protein suppresses immunity. NATURE[J]. 2020, 577(7792): 682-+, http://dx.doi.org/10.1038/s41586-019-1915-7.
[18] Kang Wang, Binyang Zheng, Li Zhang, Lunbiao Cui, Xuan Su, Qian Zhang, Zhenxi Guo, Yu Guo, Wei Zhang, Ling Zhu, Fengcai Zhu, Zihe Rao, Xiangxi Wang. Serotype specific epitopes identified by neutralizing antibodies underpin immunogenic differences in Enterovirus B. NATURE COMMUNICATIONS[J]. 2020, 11(1): http://dx.doi.org/10.1038/s41467-020-18250-w.
[19] Lu, Zuokun, Wang, Han, Zhang, Aili, Liu, Xiang, Zhou, Weihong, Yang, Cheng, Guddat, Luke, Yang, Haitao, Schofield, Christopher J, Rao, Zihe. Structures of Mycobacterium tuberculosis Penicillin-Binding Protein 3 in Complex with Five beta-Lactam Antibiotics Reveal Mechanism of Inactivation. MOLECULAR PHARMACOLOGY[J]. 2020, 97(4): 287-294, https://www.webofscience.com/wos/woscc/full-record/WOS:000517815400006.
[20] Lonhienne, Thierry, Low, Yu Shang, Garcia, Mario D, Croll, Tristan, Gao, Yan, Wang, Quan, Brillault, Lou, Williams, Craig M, Fraser, James A, McGeary, Ross P, West, Nicholas P, Landsberg, Michael J, Rao, Zihe, Schenk, Gerhard, Guddat, Luke W. Structures of fungal and plant acetohydroxyacid synthases. NATURE[J]. 2020, 586(7828): 317-+, http://dx.doi.org/10.1038/s41586-020-2514-3.
[21] 饶子和. 基础研究要常抓不懈 做实国家安全之本. 中国科技产业[J]. 2020, 15-15, http://lib.cqvip.com/Qikan/Article/Detail?id=7101988579.
[22] Wang, Panpan, Liu, Lu, Liu, Aijun, Yan, Liming, He, Yong, Shen, Shu, Hu, Mingxu, Guo, Yu, Liu, Haiguang, Liu, Chuang, Lu, Yinying, Wang, Peiyi, Deng, Fei, Rao, Zihe, Lou, Zhiyong. Structure of severe fever with thrombocytopenia syndrome virus L protein elucidates the mechanisms of viral transcription initiation. NATURE MICROBIOLOGY[J]. 2020, 5(6): 864-+, https://www.webofscience.com/wos/woscc/full-record/WOS:000528980200002.
[23] Yang, Xiaolin, Hu, Tianyu, Yang, Xiuna, Xu, Wenqing, Yang, Haitao, Guddat, Luke W, Zhang, Bing, Rao, Zihe. Structural Basis for the Inhibition of Mycobacterial MmpL3 by NITD-349 and SPIRO. JOURNAL OF MOLECULAR BIOLOGY[J]. 2020, 432(16): 4426-4434, http://dx.doi.org/10.1016/j.jmb.2020.05.019.
[24] Jin, Zhenming, Du, Xiaoyu, Xu, Yechun, Deng, Yongqiang, Liu, Meiqin, Zhao, Yao, Zhang, Bing, Li, Xiaofeng, Zhang, Leike, Peng, Chao, Duan, Yinkai, Yu, Jing, Wang, Lin, Yang, Kailin, Liu, Fengjiang, Jiang, Rendi, Yang, Xinglou, You, Tian, Liu, Xiaoce, Yang, Xiuna, Bai, Fang, Liu, Hong, Liu, Xiang, Guddat, Luke W, Xu, Wenqing, Xiao, Gengfu, Qin, Chengfeng, Shi, Zhengli, Jiang, Hualiang, Rao, Zihe, Yang, Haitao. Structure of M-pro from SARS-CoV-2 and discovery of its inhibitors. NATURE[J]. 2020, 582(7811): 289-+, http://dx.doi.org/10.1038/s41586-020-2223-y.
[25] Liu, Fengjiang, Liang, Jingxi, Zhang, Bing, Gao, Yan, Yang, Xiuna, Hu, Tianyu, Yang, Haitao, Xu, Wenqing, Guddat, Luke W, Rao, Zihe. Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC. SCIENCE ADVANCES[J]. 2020, 6(44): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608808/.
[26] Yu, Caiting, Zhao, Jinghua, Yan, Liming, Qi, Yuanbo, Guo, Xiangyang, Lou, Zhiyong, Hu, Junjie, Rao, Zihe. Structural insights into G domain dimerization and pathogenic mutation of OPA1. JOURNAL OF CELL BIOLOGY[J]. 2020, 219(7): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337494/.
[27] Zhang, Min, Wang, Ying, He, Wanli, Sun, Yao, Guo, Yan, Zhong, Weilong, Gao, Qiang, Liao, Mingyang, Wang, Xiangxi, Cai, Yan, Guo, Yu, Rao, Zihe. Design, Synthesis, and Evaluation of Novel Enterovirus 71 Inhibitors as Therapeutic Drug Leads for the Treatment of Human Hand, Foot, and Mouth Disease. JOURNAL OF MEDICINAL CHEMISTRY[J]. 2020, 63(3): 1233-1244, https://www.webofscience.com/wos/woscc/full-record/WOS:000514221700021.
[28] Zhang, Lu, Zhao, Yao, Gao, Yan, Wu, Lijie, Gao, Ruogu, Zhang, Qi, Wang, Yinan, Wu, Chengyao, Wu, Fangyu, Gurcha, Sudagar S, Veerapen, Natacha, Batt, Sarah M, Zhao, Wei, Qin, Ling, Yang, Xiuna, Wang, Manfu, Zhu, Yan, Zhang, Bing, Bi, Lijun, Zhang, Xianen, Yang, Haitao, Guddat, Luke W, Xu, Wenqing, Wang, Quan, Li, Jun, Besra, Gurdyal S, Rao, Zihe. Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol. SCIENCE[J]. 2020, 368(6496): 1211-+, http://dx.doi.org/10.1126/science.aba9102.
[29] Chen, Xiaobo, Chen, Jiayue, Yan, Bing, Zhang, Wei, Guddat, Luke W, Liu, Xiang, Rao, Zihe. Structural basis for the broad substrate specificity of two acyl-CoA dehydrogenases FadE5 from mycobacteria. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2020, 117(28): 16324-16332, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368279/.
[30] Hongri Gong, Yan Gao, Xiaoting Zhou, Yu Xiao, Weiwei Wang, Yanting Tang, Shan Zhou, Yuying Zhang, Wenxin Ji, Lu Yu, Changlin Tian, Sin Man Lam, Guanghou Shui, Luke W Guddat, LuetLok Wong, Quan Wang, Zihe Rao. Cryo-EM structure of trimeric Mycobacterium smegmatis succinate dehydrogenase with a membrane-anchor SdhF. NATURE COMMUNICATIONS[J]. 2020, 11(1): http://dx.doi.org/10.1038/s41467-020-18011-9.
[31] Yang, Yunxiang, Yang, Pan, Wang, Nan, Chen, Zhonghao, Su, Dan, Zhou, Z Hong, Rao, Zihe, Wang, Xiangxi. Architecture of the herpesvirus genome-packaging complex and implications for DNA translocation. PROTEIN & CELL[J]. 2020, 11(5): 339-351, http://lib.cqvip.com/Qikan/Article/Detail?id=7102116300.
[32] Zhang, Bing, Li, Jun, Yang, Xiaolin, Wu, Lijie, Zhang, Jia, Yang, Yang, Zhao, Yao, Zhang, Lu, Yang, Xiuna, Yang, Xiaobao, Cheng, Xi, Liu, Zhijie, Jiang, Biao, Jiang, Hualiang, Guddat, Luke W, Yang, Haitao, Rao, Zihe. Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. CELL[J]. 2019, 176(3): 636-+, http://dx.doi.org/10.1016/j.cell.2019.01.003.
[33] Cao, Lin, Chen, Jizheng, Wang, Yaxin, Yang, Yuting, Qing, Jie, Rao, Zihe, Chen, Xinwen, Lou, Zhiyong. Identification of serotonin 2A receptor as a novel HCV entry factor by a chemical biology strategy. PROTEIN & CELL[J]. 2019, 10(3): 178-195, http://lib.cqvip.com/Qikan/Article/Detail?id=7001589015.
[34] Ran Zhang, Guangxue Xu, Lin Cao, Zixian Sun, Yong He, Mengtian Cui, Yuna Sun, Shentao Li, Huapeng Li, Lan Qin, Mingxu Hu, Zhengjia Yuan, Zipei Rao, Wei Ding, Zihe Rao, Zhiyong Lou. Divergent engagements between adeno-associated viruses with their cellular receptor AAVR. NATURE COMMUNICATIONS[J]. 2019, 10(1): 1-11, http://gooa.las.ac.cn/external/index?type=-1&pid=1509682.
[35] Zhang, Ran, Cao, Lin, Cui, Mengtian, Sung, Zixian, Hu, Mingxu, Zhang, Rouxuan, Stuarts, William, Zhao, Xiaochu, Yang, Zirui, Li, Xueming, Sun, Yuna, Li, Shentao, Ding, Wei, Lou, Zhiyong, Rao, Zihe. Adeno-associated virus 2 bound to its cellular receptor AAVR. NATURE MICROBIOLOGY[J]. 2019, 4(4): 675-682, https://www.webofscience.com/wos/woscc/full-record/WOS:000461999200020.
[36] Wang, Nan, Zhao, Dongming, Wang, Jialing, Zhang, Yangling, Wang, Ming, Gao, Yan, Li, Fang, Wang, Jingfei, Bu, Zhigao, Rao, Zihe, Wang, Xiangxi. Architecture of African swine fever virus and implications for viral assembly. SCIENCE[J]. 2019, 366(6465): 640-+, [37] Manfu Wang, Xiangyang Guo, Xiuna Yang, Bing Zhang, Jie Ren, Aijun Liu, Yajun Ran, Bing Yan, Fang Chen, Luke W Guddat, Junjie Hu, Jun Li, Zihe Rao. Mycobacterial dynamin-like protein IniA mediates membrane fission. NATURECOMMUNICATIONS[J]. 2019, 10(1): 1-13, http://dx.doi.org/10.1038/s41467-019-11860-z.
[38] Ma, Dan, Wang, Zhizhi, Merrikh, Christopher N, Lang, Kevin S, Lu, Peilong, Li, Xin, Merrikh, Houra, Rao, Zihe, Xu, Wenqing. Crystal structure of a membrane-bound O-acyltransferase. NATURE[J]. 2018, 562(7726): 286-+, https://www.webofscience.com/wos/woscc/full-record/WOS:000446920400057.
[39] Qiu, Xiaodi, Lei, Yingfeng, Yang, Pan, Gao, Qiang, Wang, Nan, Cao, Lei, Yuan, Shuai, Huang, Xiaofang, Deng, Yongqiang, Ma, Wenyu, Ding, Tianbing, Zhang, Fanglin, Wu, Xingan, Hu, Junjie, Liu, ShanLu, Qin, Chengfeng, Wang, Xiangxi, Xu, Zhikai, Rao, Zihe. Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies. NATURE MICROBIOLOGY[J]. 2018, 3(3): 287-294, https://www.webofscience.com/wos/woscc/full-record/WOS:000425846200009.
[40] Jialing Wang, Shuai Yuan, Dongjie Zhu, Hao Tang, Nan Wang, Wenyuan Chen, Qiang Gao, Yuhua Li, Junzhi Wang, Hongrong Liu, Xinzheng Zhang, Zihe Rao, Xiangxi Wang. Structure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific component. NATURE COMMUNICATIONS[J]. 2018, 9(1): https://doaj.org/article/e0d44ce22fca47ef9b1e63e0558a8d9f.
[41] Cao, Lin, Zhang, Ran, Liu, Tingting, Sun, Zixian, Hu, Mingxu, Sun, Yuna, Cheng, Lingpeng, Guo, Yu, Fu, Sheng, Hu, Junjie, Li, Xiangmin, Yu, Chengqi, Wang, Hanyang, Chen, Huanchun, Li, Xueming, Fry, Elizabeth E, Stuart, David I, Qian, Ping, Lou, Zhiyong, Rao, Zihe. Seneca Valley virus attachment and uncoating mediated by its receptor anthrax toxin receptor 1. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2018, 115(51): 13087-13092, http://dx.doi.org/10.1073/pnas.1814309115.
[42] Qingqing Zhang, Huijuan Liu, Xiang Liu, Dunquan Jiang, Bingjie Zhang, Hongliang Tian, Cheng Yang, Luke W Guddat, Haitao Yang, Kaixia Mi, Zihe Rao. Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target. 蛋白质与细胞英文版[J]. 2018, 9(11): 971-975, http://lib.cqvip.com/Qikan/Article/Detail?id=676820275.
[43] Zhang, Qingqing, Liu, Huijuan, Liu, Xiang, Jiang, Dunquan, Zhang, Bingjie, Tian, Hongliang, Yang, Cheng, Guddat, Luke W, Yang, Haitao, Mi, Kaixia, Rao, Zihe. Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target. PROTEIN & CELL[J]. 2018, 9(11): 971-975, http://lib.cqvip.com/Qikan/Article/Detail?id=676820275.
[44] 郝博威, 张永艳, 韩旭, 李鑫, 王宁宁, 饶子和. 小立碗藓ACL1的晶体制备. 南开大学学报:自然科学版[J]. 2018, 51(6): 48-53, http://lib.cqvip.com/Qikan/Article/Detail?id=6100122887.
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科研活动
科研项目
（ 1 ） 小RNA病毒感染与致病机制的结构基础, 主持, 国家级, 2014-01--2018-12
（ 2 ） 生物治疗协同创新中心, 主持, 研究所（学校）, 2014-01--2018-12
（ 3 ） 生物超大分子复合体的结构、功能与调控, 主持, 部委级, 2014-01--2018-12
（ 2 ） 生物治疗协同创新中心, 主持, 研究所（学校）, 2014-01--2018-12
（ 3 ） 生物超大分子复合体的结构、功能与调控, 主持, 部委级, 2014-01--2018-12
参与会议
（1）Structural genomics of Picornavirus 国际化学生物学大会 2015-08-28
（2）Molecular Mechanism of entry of hand-foot and mouth disease (HFMD) virus 第一届世界医学峰会 2015-07-07
（3）Structural insights into the agents of hand, foot and mouth disease 亚洲生物物理大会 2015-05-08
（4）Molecular mechanism of SCARB2-mediated attachment and uncoating of EV71 2015免疫学国际研讨会 2015-04-24
（5）Structural insights into the agents of hand, foot and mouth disease 2015-04-09
（6）Molecular Mechanism of entry of hand-foot and mouth disease (HFMD) virus 2015亚太地区肿瘤生物学和医学学术会议大会 2015-03-20
（7）我国结构生物学发展现状对同步辐射蛋白质线站建设的思考 上海光源用户年会 饶子和 2009-11-29
（2）Molecular Mechanism of entry of hand-foot and mouth disease (HFMD) virus 第一届世界医学峰会 2015-07-07
（3）Structural insights into the agents of hand, foot and mouth disease 亚洲生物物理大会 2015-05-08
（4）Molecular mechanism of SCARB2-mediated attachment and uncoating of EV71 2015免疫学国际研讨会 2015-04-24
（5）Structural insights into the agents of hand, foot and mouth disease 2015-04-09
（6）Molecular Mechanism of entry of hand-foot and mouth disease (HFMD) virus 2015亚太地区肿瘤生物学和医学学术会议大会 2015-03-20
（7）我国结构生物学发展现状对同步辐射蛋白质线站建设的思考 上海光源用户年会 饶子和 2009-11-29
指导学生
已指导学生
曹晟 01 19184
孙蕾 01 19184
陈佳 01 19183
霍霞 01 19183
张文池 01 19183
章文正 01 19183
欧先金 01 19183
刘艺锦 01 19183
王岚峰 01 19183
刘学琦 01 19183
辛亮 01 19183
魏世喜 02 19183
侯海 01 19183
彭伟 01 19183
傅晟 01 19183
黄博 01 19183
童晓航 01 19183
陈瑜涛 01 19183
李爽 01 19183
周小红 01 19183
马艳林 01 19183
李元元 01 19183
吴洋 01 19183
孙玉娜 01 19183
徐继伟 01 19183
郝宁 01 19182
王璐 01 19183
李俊 01 19183
杨清竹 01 19184
官小涛 01 19183
王祥喜 01 19183
王亚鑫 01 19183
孙瑶 01 19184
董宇 01 19184
现指导学生
党明浩 01 19183
杨扬 01 19183
冉亚军 02 19183
杨盼 02 19183
王辰龙 02 19183
邱肖迪 01 19183
袁帅 01 19183
杨晓琳 02 19183
王满福 02 19183
任洁 02 19183
高海龙 02 19183
王佳灵 02 19182
王暑辉 01 19183
张兵 01 19183
钱盈 01 19183
严川强 01 19183
冯瑞 02 19183
高若谷 02 19183
冀文欣 02 19183
王男 02 19183