海洋真核微生物（原生生物）分子生态学、转录组和基因组进化

   

070703-海洋生物学

环境微生物学，原生生物学，真核微生物组学与生态

2010-09--2012-03   加拿大达尔豪斯大学   博士
2006-09--2012-06   中国海洋大学   博士
2002-09--2006-06   中国海洋大学   学士

博士

博士研究生

2017-10~现在, 中国科学院烟台海岸带研究所, 副研究员
2012-07~2017-09,中国科学院烟台海岸带研究所, 助理研究员

2020-12-05-今,山东省生态学会理事, 理事

   

（1） 教育部高等学校优秀成果自然科学奖, 二等奖, 部委级, 2019
（2） 中国科学院青年创新促进会人才, 一等奖, 院级, 2019
（3） 山东省研究生科技创新成果, 一等奖, 省级, 2012
（4） 山东省优秀博士论文, 一等奖, 省级, 2012

（ 1 ） 一种海参养殖水体长石莼、硬石莼和萱藻孢子/配子的实时定量PCR检测方法, 专利授权, 2017, 第 1 作者, 专利号: CN106868134A

   

[1] Han, Yijing, Chen, Lizhu, Zhang, Qianqian, Yu, Daode, Yang, Dinglong, Zhao, Jianmin. Hemocyte extracellular traps of Manila clam Ruditapes philippinarum: Production characteristics and antibacterial effects. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY[J]. 2021, 第 3 作者116: http://dx.doi.org/10.1016/j.dci.2020.103953.
[2] Han, Yijing, Zhang, Qianqian, Chen, Lizhu, Yang, Dinglong, Zhao, Jianmin. Mitochondria are essential for antibacterial extracellular trap formation mediated by zymosan in hemocytes of Ruditapes philippinarum. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY[J]. 2021, 第 2 作者121: http://dx.doi.org/10.1016/j.dci.2021.104094.
[3] Li, Song, Zhuang, Wenbao, PerezUz, Blanca, Zhang, Qianqian, Hu, Xiaozhong. Two Anaerobic Ciliates (Ciliophora, Armophorea) from China: Morphology and SSU rDNA Sequence, with Report of a New Species, Metopus paravestitus nov. spec. JOURNAL OF EUKARYOTIC MICROBIOLOGY[J]. 2021, 第 4 作者68(1): http://dx.doi.org/10.1111/jeu.12822.
[4] Zou, Songbao, Zhang, Qianqian, Zhang, Xiaoli, Dupuy, Christine, Gong, Jun. Environmental Factors and Pollution Stresses Select Bacterial Populations in Association With Protists. FRONTIERS IN MARINE SCIENCE[J]. 2020, 第 2 作者7: https://doaj.org/article/040916146f844ccda5e3365e177e94cb.
[5] Pan, Hongbo, Zhang, Qianqian, Dong, Jingyi, Jiang, Jiamei. Morphology and Phylogeny of Two Novel Pleurostomatids (Ciliophora, Litostomatea), Establishing a New Genus. JOURNAL OF EUKARYOTIC MICROBIOLOGY[J]. 2020, 第 2 作者67(2): 252-262, https://www.webofscience.com/wos/woscc/full-record/WOS:000504878800001.
[6] 李笑, 曲艺, 张倩倩, 张天宇, 曹瑞文, 赵建民. 海水酸化和热应激对日本鼓虾氧化应激和能量代谢的影响. 海洋与湖沼[J]. 2020, 第 3 作者51(6): 1412-1421, http://lib.cqvip.com/Qikan/Article/Detail?id=7103324262.
[7] Chi, Yong, Li, Yuqing, Zhang, Qianqian, Ma, Mingzhen, Warren, Alan, Chen, Xiangrui, Song, Weibo. New contributions to two ciliate genera (Ciliophora, Heterotrichea) based on morphological and molecular analyses, with description of a newGruberiaspecies. BMC MICROBIOLOGY[J]. 2020, 第 3 作者20(1): https://doaj.org/article/2e5ae667c79e4c7c8e39e4965669ee1c.
[8] 张天宇, 曲艺, 张倩倩, 曹瑞文, 赵建民. 海水酸化和磺胺甲恶唑复合暴露对大马蹄螺抗氧化酶活性和脂质过氧化的影响. 海洋通报[J]. 2020, 第 3 作者39(5): 594-600, http://lib.cqvip.com/Qikan/Article/Detail?id=7103596201.
[9] Zou, Songbao, Zhang, Qianqian, Gong, Jun. Comparative Transcriptomics Reveals Distinct Gene Expressions of a Model Ciliated Protozoan Feeding on Bacteria-Free Medium, Digestible, and Digestion-Resistant Bacteria. MICROORGANISMS[J]. 2020, 第 2 作者  通讯作者  8(4): https://www.webofscience.com/wos/woscc/full-record/WOS:000533510400042.
[10] Songbao Zou, Qianqian Zhang, Jun Gong. Comparative Transcriptomics Reveals Distinct Gene Expressions of a Model Ciliated Protozoa Feeding on Bacteria-Free Medium, Digestible, and Digestion-Resistant Bacteria. MICROORGANISMS[J]. 2020, 第 2 作者8(559): https://doaj.org/article/55b2254ace3e4628bc6496271ccdcfff.
[11] Fu Yingjun, Zheng Pengfei, Zhang Xiaoli, Zhang Qianqian, Ji Daode. Protist Interactions and Seasonal Dynamics in the Coast of Yantai, Northern Yellow Sea of China as Revealed by Metabarcoding. JOURNAL OF OCEAN UNIVERSITY OF CHINA[J]. 2020, 第 4 作者  通讯作者  19(4): 961-974, http://lib.cqvip.com/Qikan/Article/Detail?id=7102857184.
[12] Song, Wen, Xu, Dapeng, Zhang, Qianqian, Liu, Weiwei, Warren, Alan, Song, Weibo. Taxonomy and phylogeny of two poorly studied genera of marine oligotrich ciliates including descriptions of two new species: Cyrtostrombidium paraboreale sp. n. and Apostrombidium orientale sp. n. (Ciliophora: Spirotrichea). EUROPEAN JOURNAL OF PROTISTOLOGY[J]. 2019, 第 3 作者70: 1-16, http://dx.doi.org/10.1016/j.ejop.2019.05.001.
[13] Adl, Sina M, Bass, David, Lane, Christopher E, Lukes, Julius, Schoch, Conrad L, Smirnov, Alexey, Agatha, Sabine, Berney, Cedric, Brown, Matthew W, Burki, Fabien, Cardenas, Paco, Cepicka, Ivan, Chistyakova, Lyudmila, del Campo, Javier, Dunthorn, Micah, Edvardsen, Bente, Eglit, Yana, Guillou, Laure, Hampl, Vladimir, Heiss, Aaron A, Hoppenrath, Mona, James, Timothy Y, Karnkowska, Anna, Karpov, Sergey, Kim, Eunsoo, Kolisko, Martin, Kudryavtsev, Alexander, Lahr, Daniel J G, Lara, Enrique, Le Gall, Line, Lynn, Denis H, Mann, David G, Massana, Ramon, Mitchell, Edward A D, Morrow, Christine, Park, Jong Soo, Pawlowski, Jan W, Powell, Martha J, Richter, Daniel J, Rueckert, Sonja, Shadwick, Lora, Shimano, Satoshi, Spiegel, Frederick W, Torruella, Guifre, Youssef, Noha, Zlatogursky, Vasily, Zhang, Qianqian. Revisions to the Classification, Nomenclature, and Diversity of Eukaryotes. JOURNAL OF EUKARYOTIC MICROBIOLOGY[J]. 2019, 第 47 作者66(1): 4-119, http://dx.doi.org/10.1111/jeu.12691.
[14] Yang, Dinglong, Han, Yijing, Chen, Lizhu, Cao, Ruiwen, Wang, Qing, Dong, Zhijun, Liu, Hui, Zhang, Xiaoli, Zhang, Qianqian, Zhao, Jianmin. A bactericidal permeability-increasing protein (BPI) from manila clam Ruditapes philippinarum: Investigation on the antibacterial activities and antibacterial action mode. FISH & SHELLFISH IMMUNOLOGY[J]. 2019, 第 9 作者93: 841-850, http://dx.doi.org/10.1016/j.fsi.2019.08.050.
[15] Hu, Gege, Han, Yijing, Yang, Dinglong, Cao, Ruiwen, Wang, Qing, Liu, Hui, Dong, Zhijun, Zhang, Xiaoli, Zhang, Qianqian, Zhao, Jianmin. Molecular cloning and characterization of FADD from the manila clam Ruditapes philippinarum. FISH & SHELLFISH IMMUNOLOGY[J]. 2019, 第 9 作者88: 556-566, http://dx.doi.org/10.1016/j.fsi.2019.03.033.
[16] Yang, Dinglong, Han, Yijing, Liu, Yongliang, Cao, Ruiwen, Wang, Qing, Dong, Zhijun, Liu, Hui, Zhang, Xiaoli, Zhang, Qianqian, Zhao, Jianmin. A peptidoglycan recognition protein involved in immune recognition and immune defenses in Ruditapes philippinarum. FISH & SHELLFISH IMMUNOLOGY[J]. 2019, 第 9 作者88: 441-448, http://dx.doi.org/10.1016/j.fsi.2019.03.017.
[17] Pan, Bo, Chen, Xiao, Hou, Lina, Zhang, Qianqian, Qu, Zhishuai, Warren, Alan, Miao, Miao. Comparative Genomics Analysis of Ciliates Provides Insights on the Evolutionary History Within "Nassophorea-Synhymenia-Phyllopharyngea" Assemblage. FRONTIERS IN MICROBIOLOGY[J]. 2019, 第 4 作者10: https://doaj.org/article/17a1fe738ed849de9cc5b42d9b1b950d.
[18] Li, Guihao, Su, Lei, Zhang, Qianqian, Zhang, Xiaoli, Gong, Jun. Molecular diversity and biogeography of benthic ciliates in the Bohai Sea and Yellow Sea. ACTA OCEANOLOGICA SINICA[J]. 2019, 第 3 作者38(2): 78-86, http://lib.cqvip.com/Qikan/Article/Detail?id=7001384776.
[19] Yang, Dinglong, Han, Yijing, Chen, Lizhu, Cao, Ruiwen, Wang, Qing, Dong, Zhijun, Liu, Hui, Zhang, Xiaoli, Zhang, Qianqian, Zhao, Jianmin. A macin identified from Venerupis philippinarum: Investigation on antibacterial activities and action mode. FISH & SHELLFISH IMMUNOLOGY[J]. 2019, 第 9 作者92: 897-904, http://dx.doi.org/10.1016/j.fsi.2019.07.031.
[20] Huang, Jie B, Zhang, Tengteng, Zhang, Qianqian, Li, Yuan, Warren, Alan, Pan, Hongbo, Yan, Ying. Further insights into the highly derived haptorids (Ciliophora, Litostomatea): Phylogeny based on multigene data. ZOOLOGICA SCRIPTA[J]. 2018, 第 3 作者47(2): 231-242, http://dx.doi.org/10.1111/zsc.12269.
[21] Boscaro, Vittorio, Santoferrara, Luciana F, Zhang, Qianqian, Gentekaki, Eleni, SybergOlsen, Mitchell J, del Campo, Javier, Keeling, Patrick J. EukRef-Ciliophora: a manually curated, phylogeny-based database of small subunit rRNA gene sequences of ciliates. ENVIRONMENTAL MICROBIOLOGY[J]. 2018, 第 3 作者20(6): 2218-2230, https://www.webofscience.com/wos/woscc/full-record/WOS:000441876900034.
[22] Cao, Ruiwen, Liu, Yongliang, Wang, Qing, Zhang, Qianqian, Yang, Dinglong, Liu, Hui, Qu, Yi, Zhao, Jianmin. The impact of ocean acidification and cadmium on the immune responses of Pacific oyster, Crassostrea gigas. FISH & SHELLFISH IMMUNOLOGY[J]. 2018, 第 4 作者  通讯作者  81: 456-462, http://dx.doi.org/10.1016/j.fsi.2018.07.055.
[23] 苏蕾, 张倩倩, 龚骏. Development and evaluation of specific PCR primers targeting the ribosomal DNA-internal transcribed spacer(ITS) region of peritrich ciliates in environmental samples. 海洋湖沼学报（英文）[J]. 2018, 第 2 作者36(3): 818-826, http://lib.cqvip.com/Qikan/Article/Detail?id=675895594.
[24] Zhang, Xiaoli, Zhang, Qianqian, Yang, Anjing, Hou, Lijun, Zheng, Yanling, Zhai, Weidong, Gong, Jun. Incorporation of Microbial Functional Traits in Biogeochemistry Models Provides Better Estimations of Benthic Denitrification and Anammox Rates in Coastal Oceans. JOURNAL OF GEOPHYSICAL RESEARCH-BIOGEOSCIENCES[J]. 2018, 第 2 作者123(10): 3331-3352, https://www.webofscience.com/wos/woscc/full-record/WOS:000450721000017.
[25] Liao, Wanying, Fan, Xinpeng, Zhang, Qianqian, Xu, Yuan, Gu, Fukang. Morphology and Phylogeny of Two Novel Ciliates, Arcanisutura chongmingensis n. gen., n. sp and Naxella paralucida n. sp from Shanghai, China. JOURNAL OF EUKARYOTIC MICROBIOLOGY[J]. 2018, 第 3 作者65(1): 48-60, http://dx.doi.org/10.1111/jeu.12431.
[26] Cao, Ruiwen, Wang, Dan, Wei, Qianyu, Wang, Qing, Yang, Dinglong, Liu, Hui, Dong, Zhijun, Zhang, Xiaoli, Zhang, Qianqian, Zhao, Jianmin. Integrative Biomarker Assessment of the Influence of Saxitoxin on Marine Bivalves: A Comparative Study of the Two Bivalve Species Oysters, Crassostrea gigas, and Scallops, Chlamys farreri. FRONTIERS IN PHYSIOLOGY[J]. 2018, 第 9 作者9: https://doaj.org/article/587fb1079a7145d89c4f773477a81e08.
[27] Su Lei, Zhang Qianqian, Gong Jun. Development and evaluation of specific PCR primers targeting the ribosomal DNA-internal transcribed spacer (ITS) region of peritrich ciliates in environmental samples. JOURNAL OF OCEANOLOGY AND LIMNOLOGY[J]. 2018, 第 2 作者36(3): 818-826, http://lib.cqvip.com/Qikan/Article/Detail?id=675895594.
[28] Yang, Dinglong, Zhang, Qianqian, Wang, Qing, Chen, Lizhu, Liu, Yongliang, Cong, Ming, Wu, Huifeng, Li, Fei, Ji, Chenglong, Zhao, Jianmin. A defensin-like antimicrobial peptide from the manila clam Ruditapes philippinarum: Investigation of the antibacterial activities and mode of action. FISH & SHELLFISH IMMUNOLOGY[J]. 2018, 第 2 作者80: 274-280, http://dx.doi.org/10.1016/j.fsi.2018.06.019.
[29] 缪栋, 苏蕾, 张倩倩, 包卫洋, 龚骏. 养殖水体三种大型爆发性海洋藻类孢子/配子实时荧光定量PCR检测方法的建立与应用初探. 中国海洋大学学报(自然科学版)[J]. 2018, 第 3 作者48(8): 68-76, http://lib.cqvip.com/Qikan/Article/Detail?id=676021805.
[30] Omar, Atef, Zhang, Qianqian, Zou, Songbao, Gong, Jun. Morphology and Phylogeny of the Soil Ciliate Metopus yantaiensis n. sp (Ciliophora, Metopida), with Identification of the Intracellular Bacteria. JOURNAL OF EUKARYOTIC MICROBIOLOGY[J]. 2017, 第 2 作者64(6): 792-805, https://www.webofscience.com/wos/woscc/full-record/WOS:000415179600007.
[31] Leger, Michelle M, Kolisko, Martin, Kamikawa, Ryoma, Stairs, Courtney W, Kume, Keitaro, Cepicka, Ivan, Silberman, Jeffrey D, Andersson, Jan O, Xu, Feifei, Yabuki, Akinori, Eme, Laura, Zhang, Qianqian, Takishita, Kiyotaka, Inagaki, Yuji, Simpson, Alastair G B, Hashimoto, Tetsuo, Roger, Andrew J. Organelles that illuminate the origins of Trichomonas hydrogenosomes and Giardia mitosomes. NATURE ECOLOGY & EVOLUTION[J]. 2017, 第 12 作者1(4): 0092-0092, https://www.webofscience.com/wos/woscc/full-record/WOS:000417171500014.
[32] Shao, Chen, Li, Liqiong, Zhang, Qianqian, Song, Weibo, Berger, Helmut. Molecular Phylogeny and Ontogeny of a New Ciliate Genus, Paracladotricha salina n. g., n. sp. (Ciliophora, Hypotrichia) (vol 61, pg 371, 2014). JOURNAL OF EUKARYOTIC MICROBIOLOGY. 2017, 第 3 作者64(6): 901-902, https://www.webofscience.com/wos/woscc/full-record/WOS:000415179600016.
[33] Zhang, Qianqian, Agatha, Sabine, Zhang, Wuchang, Dong, Jun, Yu, Ying, Jiao, Nianzhi, Gong, Jun. Three rDNA Loci-Based Phylogenies of Tintinnid Ciliates (Ciliophora, Spirotrichea, Choreotrichida). JOURNAL OF EUKARYOTIC MICROBIOLOGY[J]. 2017, 第 1 作者64(2): 226-241, http://dx.doi.org/10.1111/jeu.12354.
[34] Gao, Feng, Huang, Jie, Zhao, Yan, Li, Lifang, Liu, Weiwei, Miao, Miao, Zhang, Qianqian, Li, Jiamei, Yi, Zhenzhen, ElSerehy, Hamed A, Warren, Alan, Song, Weibo. Systematic studies on ciliates (Alveolata, Ciliophora) in China: Progress and achievements based on molecular information. EUROPEAN JOURNAL OF PROTISTOLOGY. 2017, 第 7 作者61(1): 409-423, http://dx.doi.org/10.1016/j.ejop.2017.04.009.
[35] Gong, Jun, Qing, Yao, Zou, Songbao, Fu, Rao, Su, Lei, Zhang, Xiaoli, Zhang, Qianqian. Protist-Bacteria Associations: Gammaproteobacteria and Alphaproteobacteria Are Prevalent as Digestion-Resistant Bacteriain Ciliated Protozoa. FRONTIERS IN MICROBIOLOGY[J]. 2016, 第 7 作者7(X): http://www.irgrid.ac.cn/handle/1471x/1036188.
[36] 李海林, 马斌, 张晓黎, 张倩倩, 郭晓红, 范德朋, 龚骏. 滨海湿地植物芦苇可培养内生真菌的多样性. 应用生态学报[J]. 2016, 第 4 作者27(7): 2066-2074, https://www.cjae.net/CN/10.13287/j.1001-9332.201607.014.
[37] 付娆, 龚骏, 张倩倩. 土霉素对扇形游仆虫（原生生物）种群生长及遗传多样性的影响. 中国科学:生命科学[J]. 2016, 第 3 作者46(9): 1113-1120, http://ir.yic.ac.cn/handle/133337/17285.
[38] Qianqian Zhang, Sabine Agatha, Wuchang Zhang, Jun Dong, Ying Yu, Nianzhi Jiao, Jun Gong. Three rDNA Loci-Based Phylogenies of Tintinnid Ciliates (Ciliophora,Spirotrichea, Choreotrichida). THE JOURNAL OF EUKARYOTIC MICROBIOLOGY. 2016, 第 1 作者64(2): 226-241, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546602/.
[39] Gao, Feng, Warren, Alan, Zhang, Qianqian, Gong, Jun, Miao, Miao, Sun, Ping, Xu, Dapeng, Huang, Jie, Yi, Zhenzhen, Song, Weibo. The All-Data-Based Evolutionary Hypothesis of Ciliated Protists with a Revised Classification of the Phylum Ciliophora (Eukaryota, Alveolata). SCIENTIFIC REPORTS[J]. 2016, 第 3 作者6: http://www.irgrid.ac.cn/handle/1471x/1095327.
[40] Sun, Feifei, Zhang, Xiaoli, Zhang, Qianqian, Liu, Fanghua, Zhang, Jianping, Gong, Jun. Seagrass (Zostera marina) Colonization Promotes the Accumulation of Diazotrophic Bacteria and Alters the Relative Abundances of Specific Bacterial Lineages Involved in Benthic Carbon and Sulfur Cycling. APPLIED AND ENVIRONMENTAL MICROBIOLOGY[J]. 2015, 第 3 作者81(19): 6901-6914, http://dx.doi.org/10.1128/AEM.01382-15.
[41] Guo, Xiaohong, Zhang, Qianqian, Zhang, Xiaoli, Zhang, Jiasong, Gong, Jun. Marine fungal communities in water and surface sediment of a sea cucumber farming system: habitat-differentiated distribution and nutrients driving succession. FUNGAL ECOLOGY[J]. 2015, 第 2 作者14: 87-98, http://dx.doi.org/10.1016/j.funeco.2014.12.001.
[42] Zhang, Xiumei, Ji, Daode, Zhang, Qianqian, Li, Chenghua. Description and phylogeny of a new prostomatid, Metacystis similis nov spec. (Protista, Ciliophora) from the East China Sea. ZOOTAXA[J]. 2015, 第 3 作者4033(4): 584-592, http://ir.yic.ac.cn/handle/133337/13805.
[43] Shao, Chen, Li, Liqiong, Zhang, Qianqian, Song, Weibo, Berger, Helmut. Molecular Phylogeny and Ontogeny of a New Ciliate Genus, Paracladotricha salina n. g., n. sp (Ciliophora, Hypotrichia). JOURNAL OF EUKARYOTIC MICROBIOLOGY[J]. 2014, 第 3 作者61(4): 371-380, http://www.irgrid.ac.cn/handle/1471x/963238.
[44] Zhang, Qianqian, Yi, Zhenzhen, Fan, Xinpeng, Warren, Alan, Gong, Jun, Song, Weibo. Further insights into the phylogeny of two ciliate classes Nassophorea and Prostomatea (Protista, Ciliophora). MOLECULAR PHYLOGENETICS AND EVOLUTION[J]. 2014, 第 1 作者70(2): 162-170, http://dx.doi.org/10.1016/j.ympev.2013.09.015.
[45] 龚骏, 邢贝贝, 张倩倩. 隐真菌的研究进展. 中国海洋大学学报(自然科学版)[J]. 2013, 第 3 作者43(11): 27-34, http://www.irgrid.ac.cn/handle/1471x/846586.
[46] Zhang, Qianqian, Simpson, Alastair G B, Song, Weibo. Insights into the phylogeny of systematically controversial haptorian ciliates (Ciliophora, Litostomatea) based on multigene analyses. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES[J]. 2012, 第 1 作者279(1738): 2625-2635, https://www.webofscience.com/wos/woscc/full-record/WOS:000304453000017.

   

（ 1 ） 海洋寡毛类纤毛虫的转录组分析与基因组系统学研究, 负责人, 国家任务, 2016-01--2020-12
（ 2 ） 近海典型生境真核微生物分子生态学研究, 负责人, 中国科学院计划, 2019-01--2022-12
（ 3 ） 微塑料采集、分离装置和快速检测与预警技术, 负责人, 国家任务, 2020-01--2022-12
（ 4 ） 近海与蓝碳系统微生物组学与适应机制, 负责人, 国家任务, 2019-01--2021-12

（1）组学技术研究土壤原生生物降解复杂化合物和厌氧适应机制   中国动物学会原生动物学分会第二十次学术讨论会   2019-09-20

本课题组与国内外同行建立了密切的联系和合作。如烟台大学、中国海洋大学（青岛）、中国科学院海洋研究所（青岛）、中山大学（珠海）、华南师范大学（广州）等；此外，与加拿大达尔豪斯大学、英属哥伦比亚大学、塞浦路斯尼科西亚大学等有着密切的学术联系并形成了多份合作成果。

中国海洋大学

中山大学珠海分校

西班牙动物进化研究所

加拿大达尔豪斯大学