基本信息

​邱维宝,研究员,博导,国家优青

中国科学院深圳先进技术研究院
电子邮件: wb.qiu@siat.ac.cn
通信地址: 深圳市南山区西丽深圳大学城学苑大道1068号
邮政编码: 518055

实验室简介

项目组定位于新型医学超声成像与治疗关键技术研究,主要包括高性能超声换能器、新型超声成像算法和

超声仪器设备等核心技术开发。重点攻关"可落地"、"可解决临床问题" 的前沿超声技术。


面向重大临床疾病诊疗需求,项目组开展了高分辨率超声成像和低强度超声治疗等技术研究(如下),并推动相关

技术的产业转化,带动我国生物医学超声技术发展,为患者提供更好的超声诊疗方案。

1. 高频阵列超声成像换能器、超声成像算法和成像仪器系统;

2. 高分辨率内窥(血管/心腔/消化道)超声成像技术与系统;

3. 超快超声成像技术与应用(剪切波弹性、超敏血流成像、超分辨超声成像等);

4. 低强度超声治疗技术与仪器开发(神经调控、血脑屏障调控等超声设备研发)。


项目组发表JCR二区以上SCI文章近70篇,其中IEEE Trans文章30余篇;已授权发明专利32项(已产业转化16项)。

研发的多项生物医学超声新技术获得产业界认可,完成了产业转化。

教育经历

2004年获得合肥工业大学测控技术及仪器专业学士学位;

2007年获得天津大学测试计量技术及仪器专业硕士学位;

2012年美国南加州大学超声传感器研究中心访问学者,学习高分辨超声换能器及系统技术;

2012年获得香港理工大学生物医学工程博士学位;

   博士论文题目: Development of Novel Imaging Systems and Techniques for Micro-ultrasound

工作经历

2007-2009工作于中兴通讯股份有限公司,先后任职硬件/FPGA工程师、项目经理;

2012年加入中国科学院深圳先进技术研究院-医工所-影像中心,任副研究员;

2018年晋升为研究员,博士生导师;

2019年深圳市超声成像与治疗技术重点实验室,主任;

2019年中国科学院医学成像技术与装备工程实验室,副主任;

2023年超声医疗国家工程中心,副主任;

2023年医学成像科学与技术系统全国重点实验室,电子信息部副主任。

代表性科研项目

1) 国家自然科学基金国家重大科研仪器研制项目,高时空分辨声学BOLD脑功能成像仪器研制,项目负责人,在研;

2) 国家自然科学基金优秀青年科学基金项目,高分辨率超声成像,项目负责人,结题;

3) 科技部国家重点研发计划,基于环阵超声的智能三维脑血流成像系统,项目负责人,结题;

4) 科技部国家重点研发计划,新型全通道超高频阵列超声成像诊断系统,项目负责人,在研;

5) 国家自然科学基金重大仪器研制基金项目,基于超声辐射力的深部脑刺激与神经调控仪器研制,核心成员,结题;

6) 国家自然科学基金面上基金,基于双模血管内超声的易损斑块弹性及周边血流成像研究,项目负责人,结题;

7) 国家自然科学基金青年基金,基于50-100MHz 高频率超声的血管内高分辨率成像方法研究,项目负责人,结题;

8) 中国科学院前沿重点拔尖青年项目,基于高频率超声(20-50MHz)的在体小动物脑血流成像方法与系统研究,项目负责人,结题;

9) 中国科学院科研仪器设备研制项目,小动物全脑微血流超分辨超声成像仪器研制,项目负责人,结题;

10) 广东省自然科学基金杰出青年基金,基于平面波技术的高频超声成像方法及其在脑科学领域的应用研究,项目负责人,结题;

11) 深圳市科技计划项目,深圳市超声成像与治疗技术重点实验室,主任;

12) 企业委托横向项目, 生物力学超声测量装置,项目负责人,在研。

人才获奖

2014年中国科学院王宽诚教育基金获得者;

2015年参与获得中国科学院科技促进发展奖;

2015年参与获得广东省科技进步一等奖;

2015年入选深圳市海外高层次人才“孔雀计划”B类引进人才;

2015年获批广东省自然科学基金杰青基金

2016年“深圳市青年科技奖”获得者;

2017年广东省特支计划青年拔尖人才获得者;

2018年入选中国科学院青年创新促进会会员;

2020年获批国家自然科学基金“优秀青年”科学基金;

2021年参与获得中国科学院科技促进发展奖;

2022年入选中国科学院青年创新促进会“优秀会员”。

学术兼职

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control,Associate Editor;

IEEE International Ultrasonics Symposium (IUS) 国际超声年会, Technical Program Committee (TPC) Member;Session Chair;Judge of Student Paper Competition;

IEEE UFFC Ultrasounics Standing Committee (USSC) Education Committee, Co-Chairs;

IEEE-UFFC Society Special Topic Schools, Waves and Transducers School, Organizer and teaching faculty; 

IEEE Senior member;

国家科技部重点研发专项/国家自然科学基金/广东省自然科学基金/中国博士后科学基金,评审专家;

中国生物医学工程学会/医学超声工程分会,副主任委员;

中国超声医学工程学会/仪器工程开发专委会,副主任委员;

中国医学装备协会/超声装备技术分会/超声换能器专委会,副主任委员;

中国医学装备协会/超声装备技术分会,委员;

中国医学装备协会/消化病学装备与技术分会,常务委员;

中国病理生理学会/血管医学专业委员会青年工作组,委员;

中国康复医学会/脑功能检测与调控康复专业委员会,委员;

中国医师协会/超声分子影像与人工智能专委会,委员;

中国仪器仪表学会/显微仪器分会,理事;

国家卫生健康委/能力建设和继续教育超声医学专家委员会,委员;

中国科学院青促会,优秀成员;

广东省生物医学工程学会青年学术分会,副主任委员;

广东省超声医学工程学会,常务理事;

广东省生物医学工程学会,理事。


实验室招聘


实验室长期招收硕士研究生/博士研究生/博士后

请感兴趣的同学直接联系:wb.qiu@siat.ac.cn 


主要研究方向为:

1、医学超声成像与图像处理;

2、超声电子电路及仪器开发;

3、高性能超声换能器开发。


研究内容

主要研究方向为新型医学超声方法及系统:


1)高分辨率超声成像换能器与成像仪器开发


高分辨率超声成像技术和设备。(a) 高性能超声换能器;(b) 阵列超声电子系统;(c)新型超声仪器设备;(d) 超敏微血流成像技术;(e) 三维超声血流成像技术。


相关文章:

[1] J. Xia, Y. Yang, C. Hu, R. Meng, Q. Jiang, R. Liu, Y. Yu, Z. Sheng, F. Yan, L. Zhang, Z. Shi, H. Zheng, and W. Qiu*, “Evaluation brain tumor in small animals using plane-wave-based power Doppler imaging”, Ultrasound in Medicine and Biology. vol. 45, no. 3, pp. 811-822, Mar. 2019. (IF: 2.645)

[2] [Z. Zhang, R. Chen], B. Wang, T. Zhang, M. Su, R. Liu, J. Yang, X. Cao, Y. Li, H. Zheng, K. K. Shung, M. S. Humayun, Q. Zhou*, and W. Qiu*, “Development of a high-frequency KNN ceramic based lead-free linear array ultrasonic transducer”, IEEE Trans. Ultrason. Ferroelectr. Freq. Control. vol. 65, no. 11, pp. 2113-2120, Nov. 2018. (IF: 2.704)

[3]  W. Qiu*, J. Xia, Y. Shi, P. Mu, X. Wang, M. Gao, C. Wang, Y. Xiao, G. Yang, J. Liu, L. Sun, and H. Zheng*, “A delayed-excitation data acquisition method for high-frequency ultrasound imaging”, IEEE Transactions on Biomedical Engineering. vol. 65, no. 1, pp. 15-20, Jan. 2018. (IF: 3.577)

[4]  [W. Qiu, Y. Yu], F. K. Tsang, H. Zheng*, and L. Sun*, "A novel modulated excitation imaging system for micro-ultrasound," IEEE Transactions on Biomedical Engineering, vol. 60, no. 7, pp. 1884-1890, 2013. (IF: 2.233

[5]  W. Qiu, Y. Yu, H. R. Chabok, C. Liu, F. K. Tsang, Q. Zhou, K. K. Shung, H. Zheng, and L. Sun*, “A flexible annular array imaging platform for micro-ultrasound,” IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control, vol. 60, no. 1, pp. 178-86, 2013. (IF: 1.503)


2)高分辨率内窥超声成像方法与系统


 

为心血管和消化道疾病提供高分辨率内窥超声成像方法和设备。团队已经开发并产业转化的血管内超声成像关键技术:(a) 血管内超声成像原理;(b) 血管内超声换能器,直径小于1毫米,中心频率大于40MHz; (c) 高分辨率血管组织超声成像图。团队开发的新型胶囊内窥超声成像技术:(d) 胶囊超声内镜原理部件分解图;基于LiNbO3单晶材料开发的35MHz超声成像部件; (e)高分辨率小肠组织成像图,纵向分辨率小于60微米。


相关文章:

[1] [M. Su, Z. Zhang], J. Hong, Y. Huang, P. Mu, Y. Yu, R. Liu, S. Liang, H. Zheng*, and W. Qiu*, “Cable shared dual-frequency catheter for intravascular ultrasound”, IEEE Trans. Ultrason. Ferroelectr. Freq. Control. vol. 66, no. 5, pp. 849-856, May. 2019. (IF: 2.989).

[2] [J. Hong, M. Su, Y. Yu], Z. Zhang, R. Liu, Y. Huang, P. Mu, H. Zheng*, and W. Qiu*, “A dual-mode imaging catheter for intravascular ultrasound application”, IEEE Transactions on Medical Imaging. vol. 38, no. 3, pp. 657-663, Mar. 2019. (IF: 7.816)

[3]  Z. Zhang, F. Li, R. Chen, T. Zhang, X. Cao, S. Zhang, T. Shrout, H. Zheng, K. K. Shung, M. S. Humayun, W. Qiu*, and Q. Zhou*, “High performance ultrasound needle transducer based on modified PMN-PT ceramic with ultrahigh clamped dielectric permittivity”, IEEE Trans. Ultrason. Ferroelectr. Freq. Control. vol. 65, no. 2, pp. 223-230, Feb. 2018. (IF: 2.743)

[4] W. Qiu*, X. Wang, Y. Chen, Q. Fu, M. Su, L. Zhang, J. Xia, J. Dai, Y. Zhang, and H. Zheng*, “Modulated excitation imaging system for intravascular ultrasound”, IEEE Transactions on Biomedical Engineering, vol. 64, no. 8, pp. 1935-1942, Aug 2017. (IF: 3.577)

[5] X. Wang, V. Seetohul, R. Chen, M. Qian, Z. Shi, G. Yang, P. Mu, C. Wang, Z. Huang, Q. Zhou, H. Zheng, S. Cochran, and W. Qiu*, “Development of a mechanical scanning device with high-frequency ultrasound transducer for ultrasonic capsule endoscopy”, IEEE Transactions on Medical Imaging, vol. 36, no. 9, pp. 1922-1929, Sep. 2017. (IF: 3.942)


3)无创低强度超声治疗技术及仪器开发


无创低强度超声治疗技术研究与仪器开发。(a) 便携式超声治疗仪;(b) 阵列式低强度超声治疗系统模块;(c) 成像与治疗双模式面阵列超声换能器技术研究;(d) 磁共振兼容阵列系统;(e) 千阵元超声操控系统;(f) 大规模阵列超声治疗系统原理样机。


相关文章:

[1] [G. Li, W. Qiu, Z. Zhang], Q. Jiang, M. Su, R. Cai, Y. Li, F. Cai, Z. Deng, D. Xu, H. Zhang, and H. Zheng*, “Noninvasive ultrasonic neuromodulation in freely moving mice”, IEEE Transactions on Biomedical Engineering. vol. 66, no. 1, pp. 217-224, Jan. 2019. (IF: 4.288)

[2] [G. Li, W. Qiu], J. Hong, Q. Jiang, M. Su, P. Mu, G. Yang, Y. Li, C. Wang, H. Zhang, H. Zheng*, “Imaging-Guided Dual-Target Neuromodulation of the Mouse Brain Using Array Ultrasound”, IEEE Trans. Ultrason. Ferroelectr. Freq. Control. vol. 65, no. 9, pp. 1583-1589, Sep. 2018. (IF: 2.743)

[3] [Q. Jiang, G. Li], H. Zhao, W. Sheng, L. Yue, M. Su, S. Weng, L. Chan, Q. Zhou, M. S. Humayun, W. Qiu*, and H. Zheng*, “Temporal neuromodulation of retinal ganglion cells by low-frequency focused ultrasound stimulation”, IEEE Transactions on Neural Systems and Rehabilitation Engineering. vol. 26, no. 5, pp. 969-976, May. 2018. (IF: 3.41)

[4] W. Qiu, J. Zhou, Y. Chen, M. Su, G. Li, H. Zhao, S. Cao, D. Meng, C. Wang, Y. Xiao, K. H. Lam, J. Dai, and H. Zheng*, “A portable ultrasound system for non-invasive ultrasonic neuro-stimulation”, IEEE Transactions on Neural Systems and Rehabilitation Engineering. vol. 25, no. 12, pp. 2509-2515, Dec. 2017. (IF: 3.41)

[5] [M. Gao, Y. Yu], H. Zhao, G. Li, H. Jiang, C. Wang, F. Cai, L. Chan, B. Chiu, W. Qian, W. Qiu*, and H. Zheng*, “A simulation study of ultrasonic retinal prosthesis with a novel contact-lens array for non-invasive retinal stimulation”, IEEE Transactions on Neural Systems and Rehabilitation Engineering. vol. 25, no. 9, pp. 1605-11, Sep. 2017. (IF: 3.41)

期刊文章


[1]     [H. Lu, G. Xu, Y. Wang], H. Yang, D. Li, L. Huang, M. Su, C. Li, W. Qiu, Y. Mao*, W. Yu*, and F. Li*, Correlation Between Portal Vein Pressure and Subharmonic Scattering Signals From SonoVue Microbubbles in Canines, Ultrasound in Medicine & Biology, Accepted, 2022.
[2]     C. M. Wong, S. F. Chan, R. Liu, J. Zhang, W. Wu, Z. Liang, H. M. Yau, D. Wang, S. Li, K. H. Lam*, W. Qiu*, H. S. Luo, and J. Dai*, 20-MHz phased array ultrasound transducer for in vivo ultrasound imaging of small animals, Ultrasonics, vol 126, 106821, 2022.
[3]     S. Zhuo, G. Li, H. Gong, W. Qiu, H. Zheng, and P. Liang, Low-frequency, low-intensity ultrasound modulates light responsiveness of mouse retinal ganglion cells, Journal of Neural Engineering, Accepted, 2022. (IF: 4.551)
[4]     [J. Zhang, J. Liu], W. Fan, W. Qiu*, and J. Luo*, "Partial Hadamard Encoded Synthetic Transmit Aperture for High Frame Rate Imaging with Minimal l2-Norm Least Squares Method", Physics in Medicine & Biology, vol. 67, no. 10, 105002, May, 2022. (IF: 4.174)
[5]     [H. Dong, C. Shen, S. Zhao], W. Qiu, H. Zheng, C. Zhang, S. A. Cummer, Y. Wang*, D. Fang*, and L. Cheng*, "Achromatic metasurfaces by dispersion customization for ultra-broadband acoustic beam engineering", National Science Review, nwac030, Feb 2022. (IF: 17.275).
[6]     S. Liang, M. Su, B. Liu, R. Liu, H. Zheng, W. Qiu*, Z. Zhang*, “Evaluation of Blood Induced Influence for High Definition Intravascular Ultrasound (HD-IVUS)”, IEEE Trans. Ultrason. Ferroelectr. Freq. Control, vol. 69, no. 1, pp. 98-105, Jan. 2022. (IF: 3.267).
[7]     Q. Xu, H. Zhang*, H. Liu, Y. Han, W. Qiu, Z. Li*, Inhibiting autophagy flux and DNA repair of tumor cells to boost radiotherapy of orthotopic glioblastoma, Biomaterials, 280:121287, Jan 2022. (IF: 12.479).
[8]     G. Xu, H. Lu, H. Yang, D. Li, R. Liu, M. Su, B. Jin, C. Li, T. Lv, S. Du, J. Yang, W. Qiu, Y. Mao*, F. Li*, “Subharmonic Scattering of SonoVue Microbubbles within 10-40 mmHg Overpressures in Vitro”, IEEE Trans. Ultrason. Ferroelectr. Freq. Control, vol. 68, no. 12, pp. 3583-91, Dec. 2021. (IF: 3.267).
[9]     [Z. Zhang, R. Liu, G. Li], M. Su, F. Li, H. Zheng, and W. Qiu*, “A Dual-Mode 2D Matrix Array for Ultrasound Image-Guided Noninvasive Therapy”, IEEE Transactions on Biomedical Engineering. vol. 68, no. 12, pp. 3482-90, Dec. 2021. (IF: 4.756)
[10] [M. Su, X. Xia, B. Liu], Z. Zhang, R. Liu, F. Cai, W. Qiu*, and L. Sun*, “High frequency focal transducer with a Fresnel zone plate for intravascular ultrasound”, Applied Physics Letters, vol. 119, no. 14, 143702, Oct. 2021. (IF: 3.971).
[11] Y. Lu, D. Yu*, L. Wan*, X. Zhang, M. Xiang, Z. Zhang, M. Su, W. Qiu*, “The redistribution layer-first embedded fan-out wafer level packaging for 2-D ultrasonic transducer arrays”, IEEE Electron Device Letters, vol. 42, no. 9, pp. 1374-7, Sep. 2021. (IF: 4.816)
[12] [S. Liang, Z. Zhang], X. Wang, M. Su, W. Qiu*, and H. Zheng*, “Flexible Pico-Liter Acoustic Droplet Ejection Based on High-Frequency Ultrasound Transducer”, IEEE Trans. Ultrason. Ferroelectr. Freq. Control, vol. 68, no. 6, pp. 2212-8, Jun. 2021. (IF: 3.267).
[13] T. Jin, C. Zhang, F. Liu, X. Chen, G. Liang, F. Ren, S. Liang, C. Song, J. Shi, W. Qiu, X. Jiang, K. Li, L. Xi*, On-Chip Multicolor Photoacoustic Imaging Flow Cytometry, Analytical Chemistry, 2021, 93(23): 8134-8142. (IF: 8.008)
[14] C. Liu, Y. Yang, W. Qiu, Y. Chen, J. Dai, and L. Sun*, “Quantitative characterization of the colorectal cancer in a rabbit model using high-frequency endoscopic ultrasound”, Ultrasonics, vol. 110, 106289, Feb, 2021. (IF: 4.062)
[15] [J. Wang, G. Li], L. Deng, M. Mamtilahun, L. Jiang, W. Qiu, H. Zheng, J. Sun, Q. Xie*, and G. Yang*, Transcranial Focused Ultrasound Stimulation Improves Neurorehabilitation after Middle Cerebral Artery Occlusion in Mice, Aging and Disease. vol. 12, no. 1, pp. 50-60, Feb. 2021. (IF: 9.968)
[16] [J. Zhang, H. Zhou], J. Yang, J. Jia, L. Niu, Z. Sun, D. Shi, L. Meng, W. Qiu, X. Wang, H. Zheng*, and G. Wang*, “Low-intensity pulsed ultrasound ameliorates depression-like behaviors in a rat model of chronic unpredictable stress”, CNS Neurosci Ther. vol. 27, no. 2, pp. 233-43, Feb. 2021. (IF: 7.035)
[17] W. Qiu, A. Bouakaz, E. E. Konofagou, H. Zheng*, “Ultrasound for the Brain: A Review of Physical and Engineering Principles, and Clinical applications”, IEEE Trans. Ultrason. Ferroelectr. Freq. Control, vol. 68, no. 1, pp. 6-20, Jan. 2021. (IF: 3.267).
[18] J. Zhou, J. Li, H. Zhong, X. Shi, G. Yang, J. Huang, Y. Li, T. Ma, X. Long, W. Qiu*, and H. Zheng*, “Fiber-based Clock Synchronization Method for Medical Ultrasound System”, IEEE Trans. Ultrason. Ferroelectr. Freq. Control, vol. 68, no. 1, pp. 136-142, Jan. 2021. (IF: 3.267).
[19] [Z. Zhang, M. Su], F. Li, R. Liu, R. Cai, G. Li, Q. Jiang, H. Zhong, T. Shrout, S. Zhang, H. Zheng*, and W. Qiu*, “New Sm-PMN-PT Ceramic-based 2D Array for Low-intensity Ultrasound Therapy Application”, IEEE Trans. Ultrason. Ferroelectr. Freq. Control, vol. 67, no. 10, pp. 2085-2094, Oct. 2020. (IF: 2.989).
[20] [Y. Qiu, Y. Huang], Z. Zhang, B. F. Cox, R. Liu, J. Hong, P. Mu, H. S. Lay, G. Cummins, M. P. Y. Desmulliez, E. Clutton, H. Zheng, W. Qiu*, and S. Cochran, “Ultrasound capsule endoscopy with a mechanically scanning micro-ultrasound: a porcine study”, Ultrasound in Medicine and Biology, vol. 46, no. 3, pp. 796-804, Mar. 2020. (IF: 2.998).
[21] Z. Qiu, J. Guo, S. Kala, J. Zhu, Q. Xian, W. Qiu, G. Li, T. Zhu, L. Meng, R. Zhang, H. C. Chan, H. Zheng*, and L. Sun*, The Mechanosensitive Ion Channel Piezo1 Significantly Mediates In Vitro Ultrasonic Stimulation of Neurons, iScience, vol. 21, pp. 448-57, Nov 2019. (IF: 4.447).
[22] Q. Zhang, X. Pang, Z. Zhang, M. Su, J. Hong, H. Zheng, W. Qiu, and K. H. Lam*, "Miniature Transducer Using PNN-PZT-based Ceramic for Intravascular Ultrasound", IEEE Trans. Ultrason. Ferroelectr. Freq. Control, vol. 66, no. 6, pp. 1102-1109, Jun. 2019. (IF: 2.989).
[23] [M. Su, Z. Zhang], J. Hong, Y. Huang, P. Mu, Y. Yu, R. Liu, S. Liang, H. Zheng*, and W. Qiu*, “Cable shared dual-frequency catheter for intravascular ultrasound”, IEEE Trans. Ultrason. Ferroelectr. Freq. Control. vol. 66, no. 5, pp. 849-856, May. 2019. (IF: 2.989).
[24] H. Zhang, T. Wang, H. Liu, F. Ren, W. Qiu, Q. Sun, F. Yan, H. Zheng, Z. Li*, and M. Gao, Second near-infrared photodynamic therapy and chemotherapy of orthotopic malignant glioblastoma with ultra-small Cu2-xSe nanoparticles, Nanoscale, vol. 11, no. 16, pp. 7600-7608. Apr 2019. (IF: 6.895)
[25] Y. Yu, Z. Zhang, F. Cai, M. Su, Q. Jiang, Q. Zhou, M. S. Humayun, W. Qiu*, and H. Zheng*, A Novel Racing Array Transducer for Noninvasive Ultrasonic Retinal Stimulation: A Simulation Study, Sensors, vol. 19, no. 8, 1825, 2019. (IF: 3.031).
[26] Z. Zhang, W. Qiu, H. Gong, G. Li, Q. Jiang, P. Liang, H. Zheng*, and P. Zhang*, “Low-intensity ultrasound suppresses low-Mg2+-induced epileptiform discharges in juvenile mouse hippocampal slices”, Journal of Neural Engineering, vol. 16, 036006, 2019. (IF: 4.551)
[27] C. Liu, M. Xing, B. Cong, C. Qiu, D. He, C. Wang, Y. Xiao, T. Yin, M. Shao, W. Qiu, T. Ma, X. Gong, X. Chen, H. Zheng, R. Zheng, and L. Song, "In vivo transrectal imaging of canine prostate with a sensitive and compact handheld transrectal array photoacoustic probe for early diagnosis of prostate cancer", Biomed. Opt. Express, vol. 10, no. 4, pp. 1707-1717, 2019. (IF: 3.91)
[28] [J. Hong, M. Su, Y. Yu], Z. Zhang, R. Liu, Y. Huang, P. Mu, H. Zheng*, and W. Qiu*, “A dual-mode imaging catheter for intravascular ultrasound application”, IEEE Transactions on Medical Imaging. vol. 38, no. 3, pp. 657-663, Mar. 2019. (IF: 7.816)
[29] J. Xia, Y. Yang, C. Hu, R. Meng, Q. Jiang, R. Liu, Y. Yu, Z. Sheng, F. Yan, L. Zhang, Z. Shi, H. Zheng, and W. Qiu*, “Evaluation brain tumor in small animals using plane-wave-based power Doppler imaging”, Ultrasound in Medicine and Biology. vol. 45, no. 3, pp. 811-822, Mar. 2019. (IF: 2.205).
[30] [G. Li, W. Qiu, Z. Zhang], Q. Jiang, M. Su, R. Cai, Y. Li, F. Cai, Z. Deng, D. Xu, H. Zhang, and H. Zheng*, “Noninvasive ultrasonic neuromodulation in freely moving mice”, IEEE Transactions on Biomedical Engineering. vol. 66, no. 1, pp. 217-224, Jan. 2019. (IF: 4.491)
[31] [Z. Zhang, R. Chen], B. Wang, T. Zhang, M. Su, R. Liu, J. Yang, X. Cao, Y. Li, H. Zheng, K. K. Shung, M. S. Humayun, Q. Zhou*, and W. Qiu*, “Development of a KNN Ceramic-Based Lead-Free Linear Array Ultrasonic Transducer”, IEEE Trans. Ultrason. Ferroelectr. Freq. Control. vol. 65, no. 11, pp. 2113-2120, Nov. 2018. (IF: 2.989).
[32] F. Guo, Y. Wang, Z. Huang, W. Qiu, Z. Zhang, Z. Wang, J. Dong*, B. Yang, and W. Cao “Magnesium Alloy Matching Layer for PMN-PT Single Crystal Transducer Applications”, IEEE Trans. Ultrason. Ferroelectr. Freq. Control. vol. 65, no. 10, pp. 1865-1872, Oct. 2018. (IF: 2.989)
[33] H. Liu*, C. Tsai, C. Jan, H. Chang, S. Huang, M. Li, W. Qiu, and H. Zheng, “Design and implementation of a transmit/receive ultrasound phased array for brain applications”, IEEE Trans. Ultrason. Ferroelectr. Freq. Control. vol. 65, no. 10, pp. 1756-1767, Oct. 2018. (IF: 2.989)
[34] H. Zhang, T. Wang, W. Qiu, Y. Han, Q. Sun, J. Zeng, F. Yan, H. Zheng, Z. Li*, and M. Gao, “Monitoring the Opening and Recovery of the Blood–Brain Barrier with Noninvasive Molecular Imaging by Biodegradable Ultra-small Cu2–xSe Nanoparticles”, Nano Letters. vol. 18, no. 8, pp. 4985-4992, Jul. 2018. (IF: 12.279)
[35] [J. Ye, S. Tang, L. Meng], X. Li, X. Wen, S. Chen, L. Niu, X. Li, W. Qiu, H. Hu, M. Jiang, S. Shang, Q. Shu, H. Zheng*, S. Duan, and Y. Li*, "Ultrasonic control of neural activity through activation of the mechanosensitive channel MscL", Nano Letters. vol. 18, no. 7, pp. 4148-4155, Jun. 2018. (IF: 12.279)
[36] [G. Li, W. Qiu], J. Hong, Q. Jiang, M. Su, P. Mu, G. Yang, Y. Li, C. Wang, H. Zhang, H. Zheng*, “Imaging-guided dual-target neuromodulation of the mouse brain using array ultrasound”, IEEE Trans. Ultrason. Ferroelectr. Freq. Control. vol. 65, no. 9, pp. 1583-1589, Sep. 2018. (IF: 2.989)
[37] [Q. Jiang, G. Li], H. Zhao, W. Sheng, L. Yue, M. Su, S. Weng, L. Chan, Q. Zhou, M. S. Humayun, W. Qiu*, and H. Zheng*, “Temporal neuromodulation of retinal ganglion cells by low-frequency focused ultrasound stimulation”, IEEE Transactions on Neural Systems and Rehabilitation Engineering. vol. 26, no. 5, pp. 969-976, May. 2018. (IF: 3.478)
[38] Z. Zhang, F. Li, R. Chen, T. Zhang, X. Cao, S. Zhang, T. Shrout, H. Zheng, K. K. Shung, M. S. Humayun, W. Qiu*, and Q. Zhou*, “High performance ultrasound needle transducer based on modified PMN-PT ceramic with ultrahigh clamped dielectric permittivity”, IEEE Trans. Ultrason. Ferroelectr. Freq. Control. vol. 65, no. 2, pp. 223-230, Feb. 2018. (IF: 2.989)
[39] W. Qiu*, J. Xia, Y. Shi, P. Mu, X. Wang, M. Gao, C. Wang, Y. Xiao, G. Yang, J. Liu, L. Sun, and H. Zheng*, “A delayed-excitation data acquisition method for high-frequency ultrasound imaging”, IEEE Transactions on Biomedical Engineering. vol. 65, no. 1, pp. 15-20, Jan. 2018. (IF: 4.491).
[40] W. Qiu, J. Zhou, Y. Chen, M. Su, G. Li, H. Zhao, S. Cao, D. Meng, C. Wang, Y. Xiao, K. H. Lam, J. Dai, and H. Zheng*, “A portable ultrasound system for non-invasive ultrasonic neuro-stimulation”, IEEE Transactions on Neural Systems and Rehabilitation Engineering. vol. 25, no. 12, pp. 2509-2515, Dec. 2017. (IF: 3.972)
[41] [M. Gao, Y. Yu], H. Zhao, G. Li, H. Jiang, C. Wang, F. Cai, L. Chan, B. Chiu, W. Qian, W. Qiu*, and H. Zheng*, “Simulation Study of an Ultrasound Retinal Prosthesis With a Novel Contact-Lens Array for Noninvasive Retinal Stimulation”, IEEE Transactions on Neural Systems and Rehabilitation Engineering. vol. 25, no. 9, pp. 1605-11, Sep. 2017. (IF: 3.972)
[42] X. Wang, V. Seetohul, R. Chen, M. Qian, Z. Shi, G. Yang, P. Mu, C. Wang, Z. Huang, Q. Zhou, H. Zheng, S. Cochran, and W. Qiu*, “Development of a mechanical scanning device with high-frequency ultrasound transducer for ultrasonic capsule endoscopy”, IEEE Transactions on Medical Imaging, vol. 36, no. 9, pp. 1922-1929, Sep. 2017. (IF: 6.131)
[43] W. Qiu*, X. Wang, Y. Chen, Q. Fu, M. Su, L. Zhang, J. Xia, J. Dai, Y. Zhang, and H. Zheng*, “Modulated excitation imaging system for intravascular ultrasound”, IEEE Transactions on Biomedical Engineering, vol. 64, no. 8, pp. 1935-1942, Aug 2017. (IF: 4.288)
[44] C. Wang, Y. Xiao, J. Xia, W. Qiu*, and H. Zheng*, “Effects of Non-Elevation-Focalized Linear Array Transducer on Ultrasound Plane-Wave Imaging”, Sensors, 16, 1906, 2016. (IF: 2.677)
[45] [Y. Xiao, Y. Yu], L. Niu, M. Qian, Z. Deng, W. Qiu, and H. Zheng*, Quantitative evaluation of peripheral tissue elasticity for ultrasound-detected breast lesions, Clinical Radiology, vol. 71, no. 9, pp. 896-904, 2016. (IF: 2.141)
[46] [H. Fang, Y. Chen], C. M. Wong, W. Qiu, J. Dai*, Q. Li, and Q. Yan, “Anodic aluminum oxide AAO-epoxy composite acoustic matching layers for ultrasonic transducer application”, Ultrasonics, vol. 70, pp. 29-33, 2016. (IF: 2.327)
[47] G. Li, H. Zhao, H. Zhou, F. Yan, Y. Wang, C. Xu, C. Wang, L. Niu, L. Meng, S. Wu, H. Zhang, W. Qiu*, and H. Zheng*, “Improved anatomical specificity of non-invasive neuro-stimulation by high frequency (5 MHz) ultrasound”, Scientific Reports, 6, 24738, 2016. (IF: 4.259)
[48] [W. Qiu*, C. Wang], Y. Li, J. Zhou, G. Yang, Y. Xiao, G. Feng, Q. Jin, P. Mu, M. Qian, and H. Zheng*, “A scanning-mode 2D shear wave imaging (s2D-SWI) system for ultrasound elastography”, Ultrasonics, vol. 62, pp. 89-96, Sep, 2015. (IF: 1.954)
[49] Y. Yu, W. Qiu, B. Chiu, and L. Sun*, "Feasibility of multiple micro-particle trapping--A simulation study", Sensors, vol. 15, no. 3, pp. 4958-74, 2015. (IF: 2.033)
[50] [W. Qiu, Y. Chen], C. M. Wong, B. Liu, J. Dai*, and H. Zheng*, “A novel dual-frequency imaging method for intravascular ultrasound applications”, Ultrasonics, vol. 57, pp. 31-35, Mar, 2015. (IF: 1.954)
[51] [Y. Chen, W. Qiu], K. H. Lam, B. Liu, X. Jiang, H. Zheng, H. S. Luo, H. L. W. Chan, and J. Dai*, “Focused intravascular ultrasonic probe using dimpled transducer elements”, Ultrasonics, vol. 56, pp. 227-231, Feb, 2015. (IF: 1.954)
[52] [Y. Chen, K. H. Lam], D. Zhou, Q. Yue, Y. Yu, J. Wu, W. Qiu, L. Sun, C. Zhang, H. Luo, H. L. W.  Chan, and J. Dai*, “High performance relaxor-based ferroelectric single crystals for ultrasonic transducer applications”, Sensors, vol. 14, no. 8, pp. 13730-58, Jul, 2014. (IF: 2.245)
[53] W. Qiu*, Z. Ye, Y. Yu, Y. Chen, L. Chi, P. Mu, G. Li, C. Wang, Y. Xiao, J. Dai, L. Sun, H. Zheng*, "A digital multi-gate Doppler method for high frequency ultrasound", Sensors, vol. 14, no. 8, pp. 13348-60, Jul, 2014. (IF: 2.245)
[54] Q. Zhou*, K. H. Lam, H. Zheng*, W. Qiu, K. K. Shung, “Piezoelectric single crystal ultrasonic transducers for biomedical applications”, Progress in Materials Science, vol. 66, pp. 87-111, Oct, 2014. (IF: 27.417)
[55] [X. Zhang, Y. Xiao], J. Zeng, W. Qiu, M. Qian, C. Wang, R. Zheng*, and H. Zheng*, “Computer-assisted assessment of ultrasound real-time elastography: initial experience in 145 breast lesions”, European Journal of Radiology, 83, e1-e7, 2014. (IF: 2.369)
[56] [W. Qiu, Y. Yu], F. K. Tsang, H. Zheng*, and L. Sun*, "A novel modulated excitation imaging system for micro-ultrasound," IEEE Transactions on Biomedical Engineering, vol. 60, no. 7, pp. 1884-1890, 2013. (IF: 2.233)
[57] X. Zhou*, L. Sun, Y, Yu, W. Qiu, C. L. Lien, K. K. Shung. W. Yu, “Ultrasound bio-microscopic image segmentation for evaluation of zebrafish cardiac function,” IEEE Trans. Ultrason. Ferroelectr. Freq. Control, vol. 60, no. 4, pp. 718-726, 2013. (IF: 1.503)
[58] W. Qiu, Y. Yu, H. R. Chabok, C. Liu, F. K. Tsang, Q. Zhou, K. K. Shung, H. Zheng, and L. Sun*, “A flexible annular array imaging platform for micro-ultrasound,” IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control, vol. 60, no. 1, pp. 178-86, 2013. (IF: 1.503)
[59] W. Qiu, Y. Chen, X. Li, Y. Yu, W. F. Cheng, F. K. Tsang, Q. Zhou, K. K. Shung, J. Dai, and L. Sun*, “An open system for intravascular ultrasound imaging,” IEEE Trans. Ultrason. Ferroelectr. Freq. Control, vol. 59, no. 10, pp. 2201-2209, 2012. (IF: 1.822)
[60] W. Qiu, Y. Yu, F. K. Tsang, and L. Sun*, “An FPGA based open platform for ultrasound biomicroscopy,” IEEE Trans. Ultrason. Ferroelectr. Freq. Control, vol. 59, no. 7, pp. 1432-1442, July, 2012. (IF: 1.822)
[61] W. Qiu, Y. Yu, F. K. Tsang, and L. Sun*, “A multifunctional, reconfigurable pulse generator for high-frequency ultrasound imaging,” IEEE Trans. Ultrason. Ferroelectr. Freq. Control, vol. 59, no. 7, pp. 1558-1567, July, 2012. (IF: 1.822)



专利

代表性授权专利

1) 邱维宝,于妍妍,孙雷,“超声波成像系统及成像方法”,专利申请号:201210044885.6,申请日:2012-02-22,

授权公告日:2015.12.09

2) 邱维宝,朱国乾,郑海荣,韩韬,机械扇形摆动装置, 发明专利,申请号 201310332024.2,申请日:2013.07.31,

授权公告号:CN103393436B,授权公告日:2015.09.16. 

3) 郑海荣,邱维宝,黎国锋,梁长虹, 内窥式鼻咽癌超声成像装置, 发明专利,申请日:2013.07.31 申请号:201310330411.2

授权公告号:CN103385736B,授权公告日:2015.07.29

4) 邱维宝,韩韬,郑海荣,朱国乾,旋转控制装置、旋转控制回撤系统和超声成像系统,发明专利,申请日 2013.08.06

申请号 201310339993.0授权公告号:CN103393437B, 授权公告日: 2015.04.08

5) 邱维宝,牟培田,肖杨,张雪,郑海荣,基带波束合成超声成像方法及其系统,发明专利,申请号:

201310585670.X 申请日:2013-11-19,授权公开号103654853B,授权公告日: 2016-06-08 

6) 郑海荣,邱维宝,牟培田,一种基于超声时间反演的医学影像系统,申请号:201410844503.7,申请日:2014-12-30,

授权公开号,104586426,授权公告日,2017-02-22

7) 叶为镪,邱维宝,郑海荣,基于平面波的超声温度成像方法,申请号:201410856098.0,申请日:2014-12-31,

授权公开号,104523294B,授权公告日,2016-09-21

8) 郑海荣,王丛知,邱维宝,钱明,肖杨,一种超声穿颅聚焦的方法,申请号:201410855314.X 申请日:2014-12-31,

授权公告日,2017.05.10

9) 邱维宝、苏敏、赵慧霞、王晶瑶、李永川、郑海荣,超声视网膜刺激设备,发明专利,专利申请号:201511007490.9,

申请日:2015-12-29,授权公告日,2017-10-20。

10) 郑海荣,邱维宝,黎国锋,一种超声刺激神经组织的装置,专利申请号:201510250365.4,申请日:2015-5-15。

授权公告日,2018-02-27。

11) 郑海荣,邱维宝,周娟,史志谦,超声波传感器阵列的激励装置,申请号:201410855458.5,申请日:2014-12-31。

授权公告日,2018-05-11。

12) 邱维宝,苏敏,赵慧霞,王晶瑶,李永川,郑海荣,基于二维面阵探头的视网膜刺激设备,专利申请号:

201511019409.9,申请日:2015-12-29,授权公告日: 2018-11-02。

13) 邱维宝,王杏颖,胡丽,郑海荣,一种超声胶囊内窥镜,发明专利,专利申请号:201510930435.0,申请日:

2015-12-15。授权公告日,2019-01-25。

14) 邱维宝,牟培田,郑海荣,一种延迟激励超声成像方法及装置,发明专利,专利申请号:201610257356.2,

申请日:2016-4-22。授权公开号:CN105748103B,授权公告日 2019.08.23

15) 郑海荣,邱维宝,黎国锋,苏敏,蔡蕊琳,李永川,一种头戴式超声传导装置,发明专利,专利申请号:

201710771550.7,申请日:2017-08-31,授权公开号:CN107693962B,授权公告日:2019.09.17

16) 邱维宝,洪杰韩,苏敏,郑海荣,一种双换能器补偿成像方法、超声成像系统,发明专利,专利申请号:

201711408508.5,申请日:2017.12.22。授权公开号:CN108245189B,授权公告日:2019.09.20

17) 郑海荣,邱维宝,李锦成,周娟,一种阵列超声换能器的激励方法、装置、设备及存储介质,发明专利,

专利申请号:201711433149.9,申请日:2017-12-26。授权公开号:CN107913477B,授权公告日:2020-04-10。

18) 邱维宝,张利宁,黄继卿,苏敏,郭瑞彪,郑海荣,超声换能器、聚焦换能器及聚焦换能器制作方法,发明专利,

专利申请号:201711380040.3,申请日:2017.12.19。授权公开号:CN107981887B,授权公告日:2020.06.16。

19) 邱维宝,刘荣,夏静静,郑海荣,一种处理超声影像均匀性和对比度的方法和装置,发明专利,

专利申请号:201611231457.9,申请日:2016-12-27。授权公开号:CN106691505B,授权公告日:2020.07.28。

20) 邱维宝,刘荣,郑海荣,超声成像方法、系统和设备,发明专利,专利申请号:CN201711467316.1,

申请日:2017.12.28。授权公开号:CN109975814B,授权公告日:2020.09.22。

21) 邱维宝,苏敏,张志强,蔡蕊琳,李飞,郑海荣,一种多排超声成像装置以及超声成像仪器,发明专利,

专利申请号:CN201910204641.1,申请日:2019.03.18。授权公开号:CN109770945B,授权公告日:2020.09.22。

22) 邱维宝,苏敏,张志强,蔡蕊琳,郑海荣,一种穿刺超声引导装置以及穿刺超声引导设备,发明专利,

专利申请号:CN201910329546.4,申请日:2019.04.23。授权公开号:CN110025366B,授权公告日:2020.10.27。

23) 邱维宝,李锦成,周娟,郑海荣,一种确定通信链路状态的方法及控制器,发明专利,专利申请号:201711378489.6,

申请日:2017.12.19。授权公开号:CN108134655B,授权公告日:2021.01.19。

实验室招聘


实验室长期招收硕士研究生/博士研究生/博士后

请感兴趣的同学直接联系:wb.qiu@siat.ac.cn 


主要研究方向为:

1、医学超声成像与图像处理;

2、超声电子电路及仪器开发;

3、高性能超声换能器开发。