General

齐莉 女 汉族 硕导 化学研究所


Li Qi  

female  

supervisor for master students

Institute of Chemistry, Chinese Academy of Sciences


Email: qili@iccas.ac.cn
Telephone:   +86-10-82627290
Address:  No. 2 Zhongguancun Beiyijie, Beijing, P.R. China
Postcode: 100190

Research Areas


   Analytical Chemistry



Experience

Education:

Ph.D                             Chemistry department, Hebei University, Hebei, P.R. China

B.S.                               Chemistry department, Sun Yat-Sen University, Guangdong, P.R. China

1994-1995                   William Harper College, Chicago, IL, USA

Work Experience

2002.03-present        Institute of ChemistryChinese Academy of Sciences (ICCAS), associate professor / professor


Teaching Experience

2016.03-present     Prof., Teach Analytical Chemistry ​in University of Chinese Academy of Sciences


Honors & Distinctions

(1)   The First Class Award of China Analytical Instrument Association for Science and Technology award (2012, 2016)

(2)   The Second Class Award of Beijing Municipal Sciences and Technology (1998)

(3)   The Third Class Award of Beijing Municipal Sciences and Technology (1994)






2007.01-present  Board member, Beijing Society of Chromatography

2020.04-present  Editor board, Journal of Analytical Science and Technology

Publications

 In recent years, as correspondence author, published 103 SCI papers in Analytical Chemistry and other journals.

Authorized 9 patents

                                               ​

Papers

Selected publication 


1.

Recent advances in open tubular capillary   electrochromatography for enantioseparation of chiral drugs and D,L-amino   acids, TRAC-Trends in Analytical Chemistry, 2026, 194, 118525.

Corresponding author

2.

Specific recognition of cysteine in a mixed-valence   bimetallic organic framework with unique channel properties, Angewandte  Chemie-International Edition, 2025,  64, e202504014.

Corresponding author

3.

Fabrication of hierarchically mesoporous   multishelled metal-organic frameworks via templates-induced assembly/grinding strategy for immobilization of enzyme and enhancing catalytic performance, ACS Applied Materials & Interfaces, 2025, 17, 58905.

Corresponding author

4

Thermo-responsive polymer-MOF@cellulase composites with improved   catalytic activity for hydrolysis of cellulose, Chemistry-An Asian Journal, 2025, 20, 2202400990.

Corresponding author

5

Construction   of degradable liposome-templated microporous metal-organic frameworks with   high degree-of-freedom space for enzymes, Chinese Chemical Letters, 2024, 35, 109812.

Corresponding author

6

Confinement-induced   biocatalytic activity enhancement of light- and thermo-responsive   polymer@enzyme@MOF composites, ACS Applied Materials & Interfaces, 2024, 16, 36953.

Corresponding author

7

Dual stimuli-responsive   enzyme@metal-organic framework-polymer composites towards enhanced catalytic   performance for visual detection of glucose, ACS Applied Bio Materials, 2024, 7, 325.

Corresponding author

8

Open   tubular capillary electrochromatography with dual-responsive polymer as   coating for separation of chromones, Journal of Chromatography A, 2024, 1714, 464595..

Corresponding author

9

Thermo-responsive   polymer-modified metal-organic frameworks as soft-rigid enzyme-reactors for   enhancement of enzymolysis efficiency using a controllable embedding   protocol, Journal of   Materials Chemistry B, 2023, 11, 6428.

Corresponding author

10

Dual-stimuli-responsive   polymer vesicles for regulation of enzymolysis efficiency in a cascade   reaction, Chemistry-An  Asian Journal, 2023, 18, e202300285.

Corresponding author

11

Redox-responsive   polymer nanoreactors based on methionine sulfoxide for monitoring of cell   adherence, Analytical Chemistry, 2022, 94, 11807.

Corresponding author

12

In   situ determination of sialic acid on cell-surface with pH-regulated polymer   enzyme nanoreactor, Analytical Chemistry, 2021, 93, 7317.

Corresponding author

13

Simultaneous   monitoring of intracellular temperature and norepinephrine variation by fluorescent probes during norepinephrine reuptake, Analytical Chemistry,   2021, 93, 14743.

Corresponding author

14

Enzyme   immobilization on a pH-responsive porous polymer membrane for enzymatic kinetics study, Chinese Chemical Letters, 2021, 32, 3195.

Corresponding author

15

Design   of switchable enzyme carriers based on stimuli-responsive porous polymer   membranes for bio-applications, ACS Applied Bio Materials, 2021, 4, 4706.

Corresponding author

16.

Thermoresponsive   porous polymer membrane as a switchable enzyme reactor for D-amino acid   oxidase kinetics study, ACS Applied Bio Materials, 2021, 4, 966.

Corresponding author

17.

Selective capture and   in-situ controllable detection of D-glucose in cerebral systems, Analytical Chemistry, 2020, 92, 4445.

Corresponding author

18.

Simultaneous monitoring   of temperature and Ca2+ concentration variation by fluorescent   polymer during intracellular heat production, Analytical Chemistry, 2020, 92, 8579.

Corresponding author

19.

Enzyme reactor based on   reversible pH controlled catalytic polymer porous membrane, ACS Applied Materials & Interfaces, 2019, 11, 15133.

Corresponding author

20.

Simultaneous monitoring   of mitochondrial temperature and ATP fluctuation using fluorescent probes in living cells, Analytical Chemistry, 2018, 90, 12553.

Corresponding author

21.

On-line proteolysis and   glycopeptide enrichment with thermo-responsive porous polymer membrane reactors for nanoflow liquid chromatography-tandem mass spectrometry, Analytical Chemistry, 2018, 90, 3124.

Corresponding author

22.

Preparation of   polymer@AuNPs with droplets approach for sensing serum copper ions, Analytical Chemistry, 2017, 89, 2080.

Corresponding author

23.

Ratiometric fluorescent   pattern for sensing proteins using aqueous polymer-pyrene/g-cyclodextrin   inclusion complexes, Analytical Chemistry, 2016, 88,   1821.

Corresponding author

24.

Folic acid-conjugated   fluorescent polymer for up-regulation folate receptor expression study via   targeted imaging of tumor cells, Biosensors & Bioelectronics, 2016, 78, 147.

Corresponding author

25.

Construction of   fluorescent polymeric nano thermometers for intracellular temperature   imaging: A review, Biosensors & Bioelectronics, 2016, 85, 403.

Corresponding author

26.

Ratiometric fluorescent   polymeric thermometer: for thermogenesis investigation in living cells, Analytical   Chemistry, 2015, 87, 10535.

Corresponding author

27.

Ratiometric fluorescent   probe based on gold nanoclusters and alizarin red-boronic acid for monitoring   glucose in brain microdialysate, Analytical Chemistry, 2014, 86, 9758.

Corresponding author

28.

Construction of D-amino   acid oxidase reactor based on magnetic nanoparticles modified by reactive   polymer and its application in screening enzyme inhibitors, ACS Applied Materials & Interfaces, 2014, 6, 12979.

Corresponding author

29.

Poly(2-vinyl-4,4-dimethylazlactone-functionalized   magnetic nanoparticles as carriers for enzyme immobilization and its   application, ACS Applied Materials & Interfaces, 2014, 6, 21346.

Corresponding author

30.

Novel oligo(ethylene   glycol)-based molecularly imprinted magnetic nanoparticles for thermally   modulated capture and release of lysozyme, ACS Applied Materials & Interfaces, 2014, 6, 17289.

Corresponding author

31.

Thermoresponsive   oligo(ethylene glycol)-based polymer brushes on polymer monolith for   all-aqueous chromatography, ACS Applied Materials & Interfaces, 2013, 5, 12441.

Corresponding author

32.

Facile one-pot synthesis   of L-proline-stabilized fluorescent gold nanoclusters and its application as   sensing probes for serum iron, Biosensors & Bioelectronics, 2013, 49, 249.

Corresponding author

33.

Folic   acid-functionalized fluorescent gold nanoclusters with polymer as linker for   cancer cells imaging, Chemical Communications, 2013, 49,   8030.

Corresponding author

34.

Reactive polymer   function as a versatile toolbox for construction of multifunctional   superparamagnetic nanocomposites, Chemistry-A European Journal, 2012, 18, 13755.

Corresponding author

35.

Thermal responsive   fluorescent block copolymer for intracellular temperature sensing, Journal of Materials Chemistry, 2012, 22, 11543.

Corresponding author

Patents

  • Authorized Patents

    1. Li Qi, Xiao-Yu Mu, Juan Qiao, Preparation of a novel D-amino acid oxidase-based enzyme reactor, CN ZL201310594025.4

    2. Li Qi, Hai-Zhi Zhang, Xiao-Yu Mu, Juan Qiao, Lan-Qun Mao, Amino acid liquid ions as the ligands for chiral ligand exchange capillary electrophoresis application, CN ZL201210229429.9

    3. Li Qi, Jun Yang, Hui-Min Ma, Construction of porous cellulose membrane based microchip and its application, CN ZL201210122279.1

Research Interests


1.    Capillary electrophresis for chiral separation and enzyme kinetics

2.    Preparation of polymer-based micro/nano materials and its application in sensing and cell imaging

3.   Preparation of polymer monolith and its application in bio-chromatography

Collaboration

2016.7-2018.6 NSFC International Co-operation Project (Yonsei University, Korea, Prof. Meyong Hee Moon)

Students

已指导学生

韩志强                                  博士研究生  070302-分析化学  

杨    俊                                 博士研究生  070302-分析化学  

张荣月                                  博士研究生  070302-分析化学  

辛培勇                                  博士研究生  070302-分析化学  

乔    娟                                 博士研究生  070302-分析化学  

魏晓奕                                  博士研究生  070302-分析化学  

姚春荷                                  博士研究生  070302-分析化学  

张海枝                                  博士研究生  070302-分析化学  

沈    莹                                 博士研究生  070302-分析化学  

李雅萍                                  博士研究生  070302-分析化学  

木肖玉                                  博士研究生  070302-分析化学  

姜俊芳                                  硕士研究生  070302-分析化学  

李    楠                                 博士研究生  070302-分析化学  


现指导学生

沈吉                                     硕士研究生  070302-分析化学 

Nasir Ali                              博士研究生  070302-分析化学

Muhammad Ali Tajwar       硕士研究生  070302-分析化学

Rubina Jabeen                    硕士研究生  070302-分析化学

Education