基本信息
齐飞飞  男  硕导  中国科学院青岛生物能源与过程研究所
电子邮件: qiff@qibebt.ac.cn
通信地址: 青岛市崂山区松岭路189号
邮政编码:

招生信息

   
招生专业
071005-微生物学
招生方向
微生物天然产物生物合成
丝状真菌合成生物学

教育背景

2010-09--2014-06   山东大学   理学博士
2004-09--2007-06   安徽农业大学   理学硕士
2000-09--2004-06   青岛农业大学   农学学士

工作经历

   
工作简历
2020-01~现在, 中国科学院青岛生物能源与过程研究所, 副研究员
2017-01~2019-12,中国科学院青岛生物能源与过程研究所, 助理研究员
2014-08~2016-12,中国科学院青岛生物能源与过程研究所, 博士后
2007-08~2010-09,鲁南制药集团, 科研部研发人员
社会兼职
2023-04-01-今,中国微生物学会会员,

专利与奖励

   
专利成果
( 1 ) 一种积累大黄素的基因工程菌株及其构建方法和应用, 专利授权, 2021, 第 3 作者, 专利号: CN110527638B

( 2 ) 一种产大黄素的基因工程菌株及其构建方法与应用, 专利授权, 2021, 第 4 作者, 专利号: CN110540943B

( 3 ) 一种积累大黄素-8-甲醚的工程菌株及其构建方法和应用, 发明专利, 2020, 第 2 作者, 专利号: CN110964649A

( 4 ) 甘露糖苷酶I的表达基因的应用, 专利授权, 2019, 第 1 作者, 专利号: CN105671021B

出版信息

   
发表论文
[1] Zhang, Yingfang, Xun, Hang, Gao, Quan, Qi, Feifei, Sun, Jia, Tang, Feng. Chemical Constituents of the Mushroom Dictyophora indusiata and Their Anti-Inflammatory Activities. MOLECULES[J]. 2023, 第 4 作者28(6): http://dx.doi.org/10.3390/molecules28062760.
[2] Zhang, YingFang, Xun, Hang, Gao, Quan, Tang, Feng, Qi, FeiFei, Sun, Jia. Two new sesquiterpenoids from Dictyophora indusiata. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH[J]. 2023, 第 5 作者25(6): 564-570, http://dx.doi.org/10.1080/10286020.2022.2106223.
[3] Feifei Qi, Wei Zhang, Yingying Xue, Ce Geng, Zhigang Jin, Jibin Li, Qiang Guo, Xuenian Huang, 吕雪峰. Microbial Production of the Plant-derived Fungicide Physcion. Metabolic Engineering[J]. 2022, 第 1 作者
[4] Yingying Xue, Yajing Liang, Wei Zhang, Ce Geng, Dandan Feng, Xuenian Huang, Sheng Dong, Yingfang Zhang, Jia Sun, Feifei Qi, 吕雪峰. Characterization and Structural Analysis of Emodin-O-Methyltransferase from Aspergillus terreus. Journal of Agricultural and Food Chemistry[J]. 2022, 第 10 作者  通讯作者  
[5] Qi, Feifei, Zhang, Wei, Xue, Yingying, Geng, Ce, Huang, Xuenian, Sun, Jia, Lu, Xuefeng. Bienzyme-Catalytic and Dioxygenation-Mediated Anthraquinone Ring Opening. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2021, 第 1 作者143(40): 16326-16331, http://dx.doi.org/10.1021/jacs.1c07182.
[6] Wang, DeTao, Xue, YingYing, Zhang, YingFang, Xun, Hang, Guo, QiRong, Tang, Feng, Sun, Jia, Qi, FeiFei. Lignans and phenylpropanoids from the liquid juice of phyllostachys edulis. NATURAL PRODUCT RESEARCH[J]. 2021, 第 8 作者  通讯作者  35(19): 3241-3247, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000497121900001.
[7] Xu, Huifang, Liang, Weinan, Ning, Linlin, Jiang, Yuanyuan, Yang, Wenxia, Wang, Cong, Qi, Feifei, Ma, Li, Du, Lei, Fourage, Laurent, Zhou, Yongjin J, Li, Shengying. Directed Evolution of P450 Fatty Acid Decarboxylases via High-Throughput Screening towards Improved Catalytic Activity. CHEMCATCHEM[J]. 2020, 第 7 作者12(1): 80-84, https://www.webofscience.com/wos/woscc/full-record/WOS:000492792500001.
[8] Li, Fengwei, Ma, Li, Zhang, Xingwang, Chen, Jingfei, Qi, Feifei, Huang, Yinyue, Qu, Zepeng, Yao, Lishan, Zhang, Wei, Kim, EungSoo, Li, Shengying. Structure-guided manipulation of the regioselectivity of the cyclosporine A hydroxylase CYP-sb21 from Sebekia benihana. SYNTHETIC AND SYSTEMS BIOTECHNOLOGY[J]. 2020, 第 5 作者5(3): 236-243, http://lib.cqvip.com/Qikan/Article/Detail?id=7103845009.
[9] Ye, Ying, Du, Lei, Zhang, Xingwang, Newmister, Sean A, McCauley, Morgan, AlegreRequena, Juan, V, Zhang, Wei, Mu, Shuai, Minami, Atsushi, Fraley, Amy E, AdroverCastellano, Maria L, Carney, Nolan A, Shende, Vikram V, Qi, Feifei, Oikawa, Hideaki, Kato, Hikaru, Tsukamoto, Sachiko, Paton, Robert S, Williams, Robert M, Sherman, David H, Li, Shengying. Fungal-derived brevianamide assembly by a stereoselective semipinacolase. NATURE CATALYSIS[J]. 2020, 第 14 作者3(6): 497-+, http://dx.doi.org/10.1038/s41929-020-0454-9.
[10] Gao, Quan, Jiang, Hao, Tang, Feng, Cao, Haiqun, Wu, Xiangwei, Qi, Feifei, Sun, Jia, Yang, Jun. Evaluation of the bitter components of bamboo shoots using a metabolomics approach. FOOD & FUNCTION[J]. 2019, 第 6 作者10(1): 90-98, 
[11] Zhang, Wei, Du, Lei, Qu, Zepeng, Zhang, Xingwang, Li, Fengwei, Li, Zhong, Qi, Feifei, Wang, Xiao, Jiang, Yuanyuan, Men, Ping, Sun, Jingran, Cao, Shaona, Geng, Ce, Qi, Fengxia, Wan, Xiaobo, Liu, Changning, Li, Shengying. Compartmentalized biosynthesis of mycophenolic acid. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2019, 第 7 作者116(27): 13305-13310, http://ir.xtbg.org.cn/handle/353005/11335.
[12] Feifei Qi, Chao Lei, Fengwei Li, Xingwang Zhang, Jin Wang, Wei Zhang, Zhen Fan, Weichao Li, GongLi Tang, Youli Xiao, Guoping Zhao, Shengying Li. Deciphering the late steps of rifamycin biosynthesis. NATURE COMMUNICATIONS[J]. 2018, 第 1 作者9(1): http://www.irgrid.ac.cn/handle/1471x/1782302.
[13] Du, Lei, Ma, Li, Qi, Feifei, Zheng, Xianliang, Jiang, Chengying, Li, Ailei, Wan, Xiaobo, Liu, ShuangJiang, Li, Shengying. Characterization of a Unique Pathway for 4-Cresol Catabolism Initiated by Phosphorylation in Corynebacterium glutamicum. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2016, 第 3 作者291(12): 6583-6594, http://dx.doi.org/10.1074/jbc.M115.695320.
[14] Zheng, Xianliang, Fang, Bo, Han, Dongfei, Yang, Wenxia, Qi, Feifei, Chen, Hui, Li, Shengying. Improving the Secretory Expression of an - Galactosidase from Aspergillus niger in Pichia pastoris. PLOS ONE[J]. 2016, 第 5 作者11(8): http://dx.doi.org/10.1371/journal.pone.0161529.
[15] Qi, Feifei, Zhang, Weixin, Zhang, Fengjie, Chen, Guanjun, Liu, Weifeng. Deciphering the Effect of the Different N-Glycosylation Sites on the Secretion, Activity, and Stability of Cellobiohydrolase I from Trichoderma reesei. APPLIED AND ENVIRONMENTAL MICROBIOLOGY[J]. 2014, 第 1 作者80(13): 3962-3971, https://www.webofscience.com/wos/woscc/full-record/WOS:000337241400020.

科研活动

   
科研项目
( 1 ) 里氏木霉sorbicillinoid类次级代谢产物生物合成机制的研究, 负责人, 国家任务, 2017-01--2019-12
( 2 ) 高效生物合成大黄素及其甲醚衍生物土曲霉细胞工厂的设计与构建, 负责人, 国家任务, 2020-01--2023-12
( 3 ) 大黄素甲醚高产土曲霉工程菌株的设计与构建, 负责人, 境内委托项目, 2019-11--2021-11
( 4 ) 构建可以生产具有航空燃油特性的E. coli细胞工厂, 负责人, 地方任务, 2014-08--2015-07
( 5 ) 丝状真菌蒽醌化合物双加氧开环机制的研究, 负责人, 国家任务, 2023-01--2026-12
( 6 ) 泰山学者青年专家项目, 负责人, 地方任务, 2022-07--2025-06
参与会议
(1)基于土曲霉地曲霉素生物合成途径的生物农药大黄素甲醚细胞工厂构建应用研究和蒽醌开环新机制基础研究   中国微生物学会学术年会   2021-10-30
(2)利福霉素SV-B生物合成机制揭秘   中国微生物学会学术年会   2018-10-19