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生物材料表面与界面

   

080502-材料学
0805J7-仿生界面交叉科学
083100-生物医学工程

生物材料表界面
生物医用材料表面改性
医用材料表面纳米化及其生物学性能评价

2007-09--2013-09   中国科学院上海硅酸盐研究所   博士学位
2003-09--2007-06   中国科学院上海硅酸盐研究所   学士学位

   

2025-01~现在, 中国科学院上海硅酸盐研究所, 研究员
2018-01~2024-12,中国科学院上海硅酸盐研究所, 副研究员
2013-12~2017-12,中国科学院上海硅酸盐研究所, 助理研究员

2023-08-21-2027-08-20,中国生物材料学会生物材料表界面工程分会, 秘书长

   

（ 1 ） 一种兼具抗腐蚀性、抗菌和促成骨性能的可降解表面改性镁合金材料及其制备方法, 发明专利, 2023, 第 3 作者, 专利号: CN116555862A

（ 2 ） 制备钛种植体的方法及得到的钛种植体, 发明专利, 2014, 第 2 作者, 专利号: CN103736148A

（ 3 ） 一种牙科种植体及其制备方法, 发明专利, 2014, 第 2 作者, 专利号: CN103536371A

（ 4 ） 医用钛表面载金纳米管薄膜的制备方法, 发明专利, 2013, 第 2 作者, 专利号: CN103451705A

（ 5 ） 一种制备低氧氧化钛纳米管阵列的方法, 发明专利, 2014, 第 2 作者, 专利号: CN103866370A

（ 6 ） 一种用于钛金属工件阳极氧化的通用性夹具装置, 实用新型, 2013, 第 2 作者, 专利号: CN202881422U

（ 7 ） 一种基于钛金属表面的纳米复合材料及其制备方法, 发明专利, 2012, 第 2 作者, 专利号: CN102677055A

（ 8 ） 一种响应型三元异质结材料及其制备方法和应用, 发明专利, 2024, 第 3 作者, 专利号: CN117815390A

（ 9 ） 一种三氧化二钛纳米管阵列薄膜及其制备方法和应用, 发明专利, 2023, 第 4 作者, 专利号: CN117187917A

（ 10 ） 一种镁合金表面超疏水涂层的制备方法, 发明专利, 2023, 第 3 作者, 专利号: CN116988120A

   

（1） Interfering with proton and electron transfer enables antibacterial starvation therapy, SCIENCE ADVANCES, 2025, 第 8 作者
（2） Constructing Hydroxylated Graphite-Like Film with Protein Regulation on PEEK for Integrated Bone-Soft Tissue Therapy, ADVANCED FUNCTIONAL MATERIALS, 2025, 第 6 作者
（3） Metastructure and strain-defect engineered Cu-doped TiOx coating to enhance antibacterial sonodynamic therapy, BIOACTIVE MATERIALS, 2025, 第 8 作者
（4） 医用钛表面石墨烯薄膜的PECVD法制备及其性能, Preparation and Properties of Graphene Films on Medical Titanium by PECVD Method, 表面技术, 2024, 第 3 作者
（5） Metastructure "Trap" Coating by Acoustic Confinement Effect for Antibacterial Sonothermal Therapy, ADVANCED FUNCTIONAL MATERIALS, 2024, 第 8 作者
（6） Metainterface Heterostructure Enhances Sonodynamic Therapy for Disrupting Secondary Biofilms, ACS NANO, 2024, 第 7 作者
（7） Atomic Layer Deposition of Tantalum Oxide Films on 3D-Printed Ti6Al4V Scaffolds with Enhanced Osteogenic Property for Orthopedic Implants, ACS BIOMATERIALS SCIENCE & ENGINEERING, 2023, 第 5 作者
（8） Complementary and Synergistic Design of Bi-Layered Double Hydroxides Modified Magnesium Alloy toward Multifunctional Orthopedic Implants, ADVANCED HEALTHCARE MATERIALS, 2023, 第 6 作者
（9） Ferric oxide nanosheet-engineered Mg alloy for synergetic osteosarcoma photothermal/chemodynamic therapy, Ferric oxide nanosheet-engineered Mg alloy for synergetic osteosarcoma photothermal/chemodynamic therapy, JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY, 2023, 第 8 作者
（10） Comparison study of Mg(OH)2, Mg-Fe LDH, and FeOOH coatings on PEO-treated Mg alloy in anticorrosion and biocompatibility, APPLIED CLAY SCIENCE, 2022, 第 4 作者  通讯作者
（11） ��-CD/PEI/PVA composite hydrogels with superior self-healing ability and antibacterial activity for wound healing, COMPOSITES PART B-ENGINEERING, 2022, 第 7 作者
（12） Mg-Fe LDH sealed PEO coating on magnesium for biodegradation control, antibacteria and osteogenesis, Mg-Fe LDH sealed PEO coating on magnesium for biodegradation control, antibacteria and osteogenesis, JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY, 2022, 第 6 作者
（13） Complementary and Synergistic Design of Bi-Layered Double Hydroxides Modified Magnesium Alloy toward Multifunctional Orthopedic Implants, ADVANCED HEALTHCARE MATERIALS, 2022, 第 6 作者
（14） Self-assembled ferric oxyhydroxide nanosheet on PEO-coated magnesium alloy with photocatalytic/photothermal antibacterial and enhanced osteogenesis activities, CHEMICAL ENGINEERING JOURNAL, 2022, 第 9 作者
（15） 钽离子注入对镍钛合金表面生物学性能的影响, Biological Property Investigation of Nitinol Surface Implanted with Tantalum, 无机材料学报, 2022, 第 3 作者
（16） Black Mn-containing layered double hydroxide coated magnesium alloy for osteosarcoma therapy, bacteria killing, and bone regeneration, Black Mn-containing layered double hydroxide coated magnesium alloy for osteosarcoma therapy, bacteria killing, and bone regeneration, BIOACTIVE MATERIALS, 2022, 第 8 作者
（17） Biological Property Investigation of Nitinol Surface Implanted with Tantalum, JOURNAL OF INORGANIC MATERIALS, 2022, 第 3 作者
（18） Co-implantation of magnesium and zinc ions into titanium regulates the behaviors of human gingival fibroblasts, Co-implantation of magnesium and zinc ions into titanium regulates the behaviors of human gingival fibroblasts, BIOACTIVE MATERIALS, 2021, 第 5 作者  通讯作者
（19） Osteogenesis, angiogenesis and immune response of Mg-Al layered double hydroxide coating on pure Mg, Osteogenesis, angiogenesis and immune response of Mg-Al layered double hydroxide coating on pure Mg, BIOACTIVE MATERIALS, 2021, 第 6 作者  通讯作者
（20） A tailored positively-charged hydrophobic surface reduces the risk of implant associated infections, ACTA BIOMATERIALIA, 2020, 第 7 作者
（21） Interface effects on regulating the behaviors of human gingival fibroblasts on titanium by Zn-PIII, SURFACE & COATINGS TECHNOLOGY, 2020, 第 3 作者  通讯作者
（22） A facile and universal strategy to endow implant materials with antibacterial ability via alkalinity disturbing bacterial respiration, BIOMATERIALS SCIENCE, 2020, 第 5 作者
（23） Induced antibacterial capability of TiO2 coatings in visible light via nitrogen ion implantation, TRANSACTIONS OF NONFERROUS METALS SOCIETY OF CHINA, 2020, 第 2 作者  通讯作者
（24） Enhanced osteogenic activity and bacteriostatic effect of TiO2 coatings via hydrogen ion implantation, MATERIALS LETTERS, 2019, 第 2 作者  通讯作者
（25） 3D-printed nanocomposite scaffolds with tunable magnesium ionic microenvironment induce in situ bone tissue regeneration, APPLIED MATERIALS TODAY, 2019, 第 10 作者
（26） Regulating the Behavior of Human Gingival Fibroblasts by sp(2) Domains in Reduced Graphene Oxide, ACS BIOMATERIALS SCIENCE & ENGINEERING, 2019, 第 5 作者  通讯作者
（27） A surface-engineered multifunctional TiO2 based nano-layer simultaneously elevates the corrosion resistance, osteoconductivity and antimicrobial property of a magnesium alloy, ACTA BIOMATERIALIA, 2019, 第 4 作者
（28） Synergistic effects of titania nanotubes and silicon to enhance the osteogenic activity, COLLOIDS AND SURFACES B-BIOINTERFACES, 2018, 第 2 作者
（29） 碳离子注入医用Ti性能研究, Properties of Carbon Ion Implanted Biomedical Titanium, ACTA METALLURGICA SINICA, 2017, 第 2 作者
（30） Osteogenesis Catalyzed by Titanium-Supported Silver Nanoparticles, ACS APPLIED MATERIALS & INTERFACES, 2017, 第 6 作者
（31） Layer-Number Dependent Antibacterial and Osteogenic Behaviors of Graphene Oxide Electrophoretic Deposited on Titanium, ACS APPLIED MATERIALS AND INTERFACES, 2017, 第 4 作者
（32） How oxygen-containing groups on graphene influence the antibacterial behaviors, ADVANCED MATERIALS INTERFACES, 2017, 第 5 作者
（33） Si-doped porous TiO2 coatings enhanced in vitro angiogenic behavior of human umbilical vein endothelial cells, COLLOIDS AND SURFACES B-BIOINTERFACES, 2017, 第 5 作者
（34） Osteogenesis Catalyzed by Titanium-Supported Silver Nanoparticles, ACS APPLIED MATERIALS AND INTERFACES, 2017, 第 6 作者
（35） Properties of Carbon Ion Implanted Biomedical Titanium, JINSHU XUEBAO/ACTA METALLURGICA SINICA, 2017, 第 2 作者
（36） Properties of Carbon Ion Implanted Biomedical Titanium, ACTA METALLURGICA SINICA, 2017, 第 2 作者
（37） M2 macrophages contribute to osteogenesis and angiogenesis on nanotubular TiO2surfaces, JOURNAL OF MATERIALS CHEMISTRY B, 2017, 第 2 作者
（38） Cytocompatibility and antibacterial activity of titania nanotubes incorporated with gold nanoparticles, COLLOIDS AND SURFACES B-BIOINTERFACES, 2016, 第 2 作者
（39） Enhanced osteogenic activity of poly ether ether ketone using calcium plasma immersion ion implantation, COLLOIDS AND SURFACES B-BIOINTERFACES, 2016, 第 2 作者
（40） RBMSC and bacterial responses to isoelastic carbon fiber-reinforced poly(ether-ether-ketone) modified by zirconium implantation, JOURNAL OF MATERIALS CHEMISTRY B, 2016, 第 2 作者
（41） Antibacterial Surface Design of Titanium-Based Biomaterials for Enhanced Bacteria-Killing and Cell-Assisting Functions Against Periprosthetic Joint Infection, ACS APPLIED MATERIALS & INTERFACES, 2016, 第 3 作者
（42） Calcium ion modification of TiO2 nanotube arrays to enhance apatite formation, MATERIALS TECHNOLOGY, 2016, 第 3 作者
（43） Enhanced osteogenic and selective antibacterial activities on micro-/nano-structured carbon fiber reinforced polyetheretherketone, JOURNAL OF MATERIALS CHEMISTRY B, 2016, 第 3 作者
（44） Cytocompatibility of Si-incorporated TiO2 nanopores films, COLLOIDS AND SURFACES B-BIOINTERFACES, 2015, 第 1 作者
（45） Selenium doped Ni���Ti layered double hydroxide (Ni���Ti LDH) films with selective inhibition effect to cancer cells and bacteria, RSC ADVANCES, 2015, 第 3 作者
（46） Enhanced osteointegration on tantalum-implanted polyetheretherketone surface with bone-like elastic modulus, BIOMATERIALS, 2015, 第 3 作者
（47） Balancing the Osteogenic and Antibacterial Properties of Titanium by Codoping of Mg and Ag: An in Vitro and in Vivo Study, ACS APPLIED MATERIALS & INTERFACES, 2015, 第 5 作者
（48） Selective biofunctional modification of titanium implants for osteogenic and antibacterial applications, JOURNAL OF MATERIALS CHEMISTRY B, 2014, 第 1 作者
（49） Multilevel surface engineering of nanostructured TiO2 on carbon-fiber-reinforced polyetheretherketone, BIOMATERIALS, 2014, 第 3 作者
（50） Synergistic effects of dual Zn/Ag ion implantation in osteogenic activity and antibacterial ability of titanium, BIOMATERIALS, 2014, 第 4 作者
（51） Plasmonic gold nanoparticles modified titania nanotubes for antibacterial application, APPLIED PHYSICS LETTERS, 2014, 第 3 作者
（52） Vacuum extraction enhances rhPDGF-BB immobilization on nanotubes to improve implant osseointegration in ovariectomized rats, NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2014, 第 3 作者
（53） Multifunctional Mn-containing titania coatings with enhanced corrosion resistance, osteogenesis and antibacterial activity, JOURNAL OF MATERIALS CHEMISTRY B, 2014, 第 2 作者
（54） 阳极氧化法制备医用钛纳米结构表面的工艺研究, Study on Technique of Nanostructured Surface of Medical Titanium Prepared by Anodic Oxidation, 材料科学, 2013, 第 2 作者
（55） Adhesion, proliferation and differentiation of osteoblasts on zirconia films prepared by cathodic arc deposition, BIO-MEDICAL MATERIALS AND ENGINEERING, 2013, 第 4 作者
（56） Adhesion of osteoblast-like cell on silicon-doped TiO2 film prepared by cathodic arc deposition, BIOTECHNOLOGY LETTERS, 2013, 第 3 作者
（57） Effect of Si-incorporation on hydrophilicity and bioactivity of titania film, Surface and Coatings Technology, SURFACE & COATINGS TECHNOLOGY, 2013, 第 1 作者
（58） Effect of Si-incorporation on hydrophilicity and bioactivity of titania film, SURFACE & COATINGS TECHNOLOGY, 2013, 第 1 作者
（59） Nanotube array controlled carbon plasma deposition, APPLIED PHYSICS LETTERS, 2013, 第 1 作者  通讯作者
（60） Proliferation and differentiation of osteoblastic cells on silicon-doped TiO2 film deposited by cathodic arc, BIOMEDICINE & PHARMACOTHERAPY, 2012, 第 3 作者
（61） Biological Behavior of Osteoblast-like Cells on Titania and Zirconia Films Deposited by Cathodic Arc Deposition, BIOINTERPHASES, 2012, 第 4 作者

   

（ 1 ） 医用钛合金表面声学超结构构建及其智能响应特性, 参与, 国家任务, 2025-01--2025-12
（ 2 ） 新型骨植入材料与器械关键技术及产品研发, 参与, 地方任务, 2024-01--2026-12
（ 3 ） 基于微环境定向调控可抑制骨与皮肤肿瘤复发的生物活性材料研制, 参与, 国家任务, 2021-12--2024-11
（ 4 ） 可降解镁骨内固定器械产品开发, 负责人, 地方任务, 2021-10--2023-09
（ 5 ） 钛表面聚吡咯基仿生薄膜的构建及其生物效应机制探讨, 负责人, 地方任务, 2020-07--2023-06
（ 6 ） 医用钛材料穿龈表面石墨烯薄膜构建及其软组织密封机制研究, 负责人, 国家任务, 2020-01--2023-12
（ 7 ） 新型牙种植体用钛合金及其表面构建机制, 参与, 国家任务, 2019-01--2023-12