基本信息
彭惺蓉  女    中国科学院昆明植物研究所
电子邮件: pengxingrong@mail.kib.ac.cn
通信地址: 云南省昆明市盘龙区蓝黑路132号中国科学院昆明植物研究所
邮政编码: 650201

招生信息

   
招生专业
100701-药物化学
招生方向
天然药物化学

教育背景

2012-09--2015-07   中国科学院昆明植物研究所   理学博士
2009-09--2012-06   云南农业大学   理学硕士
2005-09--2009-06   天津医科大学   理学学士

工作经历

   
工作简历
2019-01~现在, 中国科学院昆明植物研究所, 副研究员
2015-08~2018-12,中国科学院昆明植物研究所, 助理研究员

专利与奖励

   
专利成果
[1] 彭惺蓉, 罗荣灿, 邱明华, 姚永刚, 冉晓倩, 胡贵林, 郭亚蓉, 李忠荣, 周琳. Ganoapplin A和ganoapplin B及其药物组合物和应用. 202210994135.9, 2022-08-19.

[2] 邱明华, 周琳, 李忠荣, 彭惺蓉. 酥油咖啡食用饮品或速溶酥油咖啡及其制备方法. CN: CN106858000A, 2017-06-20.

[3] 邱明华, 周琳, 李忠荣, 彭惺蓉. 酥油咖啡食用饮品或速溶酥油咖啡及其制备方法. CN: CN106858000A, 2017-06-20.

[4] 邱明华, 于慕湲, 王劲松, 万落生, 彭惺蓉, 李忠荣, 周琳. 玛咖-乙内硫脲A的制备方法. CN: CN104829621A, 2015-08-12.

[5] 邱明华, 于慕湲, 王劲松, 万落生, 彭惺蓉, 李忠荣, 周琳. 玛咖-乙内硫脲A的制备方法. CN: CN104829621A, 2015-08-12.

[6] 邱明华, 万落生, 彭惺蓉, 李忠荣, 周琳, 于慕湲. 一种治疗光化性角化病的原料药物巨大戟醇甲基丁烯酸酯的制备方法. CN: CN104649901A, 2015-05-27.

[7] 邱明华, 万落生, 彭惺蓉, 李忠荣, 周琳, 于慕湲. 一种治疗光化性角化病的原料药物巨大戟醇甲基丁烯酸酯的制备方法. CN: CN104649901A, 2015-05-27.

出版信息

   
发表论文
[1] DaShuang Fang, ChunRu Cheng, MingHua Qiu, XingRong Peng. Diverse meroterpenoids with α-glucosidase inhibitory activity from Ganoderma cochlear. FITOTERAPIA. 2023, 165: http://dx.doi.org/10.1016/j.fitote.2022.105420.
[2] 彭惺蓉, Sybille B. Unsicker, Jonathan Gershenzon, Minghua Qiu. Structural diversity, hypothetical biosynthesis, chemical synthesis, and biological activity of Ganoderma meroterpenoids. Natural Product Reports[J]. 2023, [3] Peng, Xingrong, Luo, Rongcan, Ran, Xiaoqian, Guo, Yarong, Yao, YongGang, Qiu, Minghua. Ganoapplins A and B with an unprecedented 6/6/6/5/6-fused pentacyclic skeleton from Ganoderma inhibit Tau pathology through activating autophagy. BIOORGANIC CHEMISTRY[J]. 2023, 132: http://dx.doi.org/10.1016/j.bioorg.2023.106375.
[4] Su, HaiGuo, Liang, HangFei, Hu, GuiLin, Zhou, Lin, Peng, XingRong, Bi, HuiChang, Qiu, MingHua. Applanoids A-E as the First Examples of C-15/C-20 Michael Adducts in Ganoderma Triterpenoids and Their PXR Agonistic Activity. CHINESE JOURNAL OF CHEMISTRY[J]. 2022, 40(22): 2633-2641, http://dx.doi.org/10.1002/cjoc.202200318.
[5] Peng, XingRong, Wang, Qian, Su, HaiGuo, Zhou, Lin, Xiong, WenYong, Qiu, MingHua. Anti-Adipogenic Lanostane-Type Triterpenoids from the Edible and Medicinal Mushroom Ganoderma applanatum. JOURNAL OF FUNGI[J]. 2022, 8(4): http://dx.doi.org/10.3390/jof8040331.
[6] Peng, XingRong, Luo, RongCan, Su, HaiGuo, Zhou, Lin, Ran, XiaoQian, Guo, YaRong, Yao, YongGang, Qiu, MingHua. (+/-)-Spiroganoapplanin A, a complex polycyclic meroterpenoid dimer from Ganoderma applanatum displaying potential against Alzheimer's disease. ORGANIC CHEMISTRY FRONTIERS[J]. 2022, 9(11): 3093-3101, http://dx.doi.org/10.1039/d2qo00246a.
[7] Peng, XingRong, Zhang, RanRan, Liu, JunHong, Li, ZhongRong, Zhou, Lin, Qiu, MingHua. Lepithiohydimerins A-D: Four Pairs of Neuroprotective Thiohydantoin Dimers Bearing a Disulfide Bond from Maca (Lepidium meyenii Walp.). CHINESE JOURNAL OF CHEMISTRY[J]. 2021, 39(10): 2738-2744, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000681331200001.
[8] Peng, XingRong, Huang, YanJie, Liu, JunHong, Zhang, RanRan, Li, ZhongRong, Zhou, Lin, Qiu, MingHua. 1H qNMR-based quantitative analysis of total macamides in five maca (Lepidium meyenii Walp.) dried naturally. JOURNAL OF FOOD COMPOSITION AND ANALYSIS[J]. 2021, 100: http://dx.doi.org/10.1016/j.jfca.2021.103917.
[9] Peng, Xingrong, Su, Haiguo, Wang, Huirong, Hu, Guilin, Hu, Kun, Zhou, Lin, Qiu, Minghua. Applanmerotic acids A and B, two meroterpenoid dimers with an unprecedented polycyclic skeleton from Ganoderma applanatum that inhibit formyl peptide receptor 2. ORGANIC CHEMISTRY FRONTIERS[J]. 2021, 8(13): 3381-3389, http://dx.doi.org/10.1039/d1qo00294e.
[10] Hou, Tao, Xu, Fangfang, Peng, Xingrong, Zhou, Han, Zhang, Xiuli, Qiu, Minghua, Wang, Jixia, Liu, Yanfang, Liang, Xinmiao. Label-free cell phenotypic study of opioid receptors and discovery of novel mu opioid ligands from natural products. JOURNAL OF ETHNOPHARMACOLOGY[J]. 2021, 270: http://dx.doi.org/10.1016/j.jep.2021.113872.
[11] Su, HaiGuo, Wang, Qian, Zhou, Lin, Peng, XingRong, Xiong, WenYong, Qiu, Ming Hua. Functional triterpenoids from medicinal fungi Ganoderma applanatum: A continuous search for antiadipogenic agents. BIOORGANIC CHEMISTRY[J]. 2021, 112: http://dx.doi.org/10.1016/j.bioorg.2021.104977.
[12] Peng, XingRong, Wang, Qian, Wang, HuiRong, Hu, Kun, Xiong, WenYong, Qiu, MingHua. FPR2-based anti-inflammatory and anti-lipogenesis activities of novel meroterpenoid dimers from Ganoderma. BIOORGANIC CHEMISTRY[J]. 2021, 116: http://dx.doi.org/10.1016/j.bioorg.2021.105338.
[13] Zhou, Han, Peng, Xingrong, Hou, Tao, Zhao, Nan, Qiu, Minghua, Zhang, Xiuli, Liang, Xinmiao. Identification of novel phytocannabinoids from Ganoderma by label-free dynamic mass redistribution assay. JOURNAL OF ETHNOPHARMACOLOGY[J]. 2020, 246: http://dx.doi.org/10.1016/j.jep.2019.112218.
[14] Peng, XingRong, Shi, QiangQiang, Yang, Jing, Su, HaiGuo, Zhou, Lin, Qiu, MingHua. Meroapplanins A-E: Five Meroterpenoids with a 2,3,4,5-Tetrahydropyridine Motif from Ganoderma applanatum. JOURNAL OF ORGANIC CHEMISTRY[J]. 2020, 85(11): 7446-7451, http://ir.kib.ac.cn/handle/151853/72178, http://www.irgrid.ac.cn/handle/1471x/6927943, http://ir.kib.ac.cn/handle/151853/72179, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000538764000057&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=3a85505900f77cc629623c3f2907beab.
[15] Su, HaiGuo, Peng, XingRong, Shi, QiangQiang, Huang, YanJie, Zhou, Lin, Qiu, MingHua. Lanostane triterpenoids with anti-inflammatory activities from Ganoderma lucidum. PHYTOCHEMISTRY[J]. 2020, 173: http://dx.doi.org/10.1016/j.phytochem.2019.112256.
[16] Huang, Yanjie, Wei, Gang, Peng, Xingrong, Hu, Guilin, Su, Haiguo, Liu, Junli, Chen, Xia, Qiu, Minghua. Triterpenoids from functional mushroom Ganoderma resinaceum and the novel role of Resinacein S in enhancing the activity of brown/beige adipocytes. FOOD RESEARCH INTERNATIONAL[J]. 2020, 136: http://dx.doi.org/10.1016/j.foodres.2020.109303.
[17] Wang, Huirong, Peng, Xingrong, Ge, Yunjun, Zhang, Shuo, Wang, Zhenyi, Fan, Yu, Huang, Wei, Qiu, Minghua, Ye, Richard D. A Ganoderma-Derived Compound Exerts Inhibitory Effect Through Formyl Peptide Receptor 2. FRONTIERS IN PHARMACOLOGY[J]. 2020, 11: https://doaj.org/article/95757b8246c543ef900436539d1a5299.
[18] Hu, Guilin, Peng, Xingrong, Gao, Ya, Huang, Yanjie, Li, Xian, Su, Haiguo, Qiu, Minghua. Effect of roasting degree of coffee beans on sensory evaluation: Research from the perspective of major chemical ingredients. FOOD CHEMISTRY[J]. 2020, 331: http://dx.doi.org/10.1016/j.foodchem.2020.127329.
[19] Hu, Guilin, Peng, Xingrong, Wang, Xia, Li, Xian, Li, Xing, Qiu, Minghua. Excavation of coffee maturity markers and further research on their changes in coffee cherries of different maturity. FOOD RESEARCH INTERNATIONAL[J]. 2020, 132: http://dx.doi.org/10.1016/j.foodres.2020.109121.
[20] Su, HaiGuo, Wang, Qian, Zhou, Lin, Peng, XingRong, Xiong, WenYong, Qiu, MingHua. Highly oxygenated lanostane triterpenoids from Ganoderma applanatum as a class of agents for inhibiting lipid accumulation in adipocytes. BIOORGANIC CHEMISTRY[J]. 2020, 104: http://dx.doi.org/10.1016/j.bioorg.2020.104263.
[21] Peng Xingrong. Highly oxygenated lanostane triterpenoids from Ganoderma applanatum as a class of agents for inhibiting lipid accumulation in adipocytes Highly oxygenated lanostane triterpenoids from Ganoderma ap class of agents for inhibiting lipid accumulation in adipocytes. Bioorganic Chemistry. 2020, [22] Dong, Jinrun, Peng, Xingrong, Lu, Shuangyang, Zhou, Lin, Qiu, Minghua. Hepatoprotective steroids from roots of Cynanchum otophyllum. FITOTERAPIA[J]. 2019, 136: 104171-, http://dx.doi.org/10.1016/j.fitote.2019.104171.
[23] Lu, ShuangYang, Peng, XingRong, Dong, JinRun, Yan, Hui, Kong, QingHua, Shi, QiangQiang, Li, DaShan, Zhou, Lin, Li, ZhongRong, Qiu, MingHua. Aromatic constituents from Ganoderma lucidum and their neuroprotective and anti-inflammatory activities. FITOTERAPIA[J]. 2019, 134: 58-64, http://dx.doi.org/10.1016/j.fitote.2019.01.013.
[24] Peng, XingRong, Su, HaiGuo, Liu, JunHong, Huang, YanJie, Yang, XinZhi, Li, ZhongRong, Zhou, Lin, Qiu, MingHua. C30 and C31 Triterpenoids and Triterpene Sugar Esters with Cytotoxic Activities from Edible Mushroom Fomitopsis pinicola (Sw. Ex Fr.) Krast. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2019, 67(37): 10330-10341, [25] Wang, Xia, Peng, Xingrong, Lu, Jing, Hu, Guilin, Qiu, Minghua. Ent-kaurane diterpenoids from the cherries of Coffea arabica. FITOTERAPIA[J]. 2019, 132: 7-11, http://dx.doi.org/10.1016/j.fitote.2018.08.023.
[26] Peng Xingrong. Rearranged lanostane-type triterpenoids with anti- hepatic fibrosis activities from Ganoderma applanatum. RSC Advances. 2019, [27] Zhang, Ling, Peng, Xingrong, Zhao, Gaoting, Xia, Jianjun, Lu, Jing, Zhou, Lin, Wang, Kunmiao, Li, Zhihua, Qiu, Minghua. Three new C23 steroids from the leaves and stems of Nicandra physaloides. STEROIDS[J]. 2019, 150: 108424-, http://dx.doi.org/10.1016/j.steroids.2019.06.001.
[28] Peng, XingRong, Li, Lei, Dong, JinRun, Lu, ShuangYang, Lu, Jing, Li, XiaoNian, Zhou, Lin, Qiu, MingHua. Lanostane-type triterpenoids from the fruiting bodies of Ganoderma applanatum. PHYTOCHEMISTRY[J]. 2019, 157: 103-110, http://ir.kib.ac.cn/handle/151853/63601.
[29] Tian, XiaoXue, Peng, XingRong, Yu, MuYuan, Huang, YanJie, Wang, Xia, Zhou, Lin, Qiu, Minghua. Hydantoin and thioamide analogues from Lepidium meyenii. PHYTOCHEMISTRY LETTERS[J]. 2018, 25: 70-73, http://dx.doi.org/10.1016/j.phytol.2018.03.011.
[30] Peng, Xingrong, Wang, Xia, Chen, Long, Yang, Han, Li, Lei, Lu, Shuangyang, Zhou, Lin, Qiu, Minghua. Racemic meroterpenoids from Ganoderma cochlear. FITOTERAPIA[J]. 2018, 127: 286-292, http://dx.doi.org/10.1016/j.fitote.2018.03.005.
[31] Peng, XingRong, Lu, ShuangYang, Shao, LiDong, Zhou, Lin, Qiu, MingHua. Structural Elucidation and Biomimetic Synthesis of (+/-)-Cochlactone A with Anti-Inflammatory Activity. JOURNAL OF ORGANIC CHEMISTRY[J]. 2018, 83(10): 5516-5522, https://www.webofscience.com/wos/woscc/full-record/WOS:000432900800018.
[32] Peng, XingRong, Huang, YanJie, Lu, ShuangYang, Yang, Jing, Qiu, MingHua. Ganolearic Acid A, a Hexanorlanostane Triterpenoid with a 3/5/6/5-Fused Tetracyclic Skeleton from Ganoderma cochlear. JOURNAL OF ORGANIC CHEMISTRY[J]. 2018, 83(21): 13178-13183, http://ir.kib.ac.cn/handle/151853/63228.
[33] XingRong Peng, YanJie Huang, ShuangYang Lu, Jing Yang, MingHua Qiu. Ganolearic Acid A, a Hexanorlanostane Triterpenoid with a 3/5/6/5Fused Tetracyclic Skeleton from Ganoderma cochlear. J. ORG. CHEM[J]. 2018, 83(21): 13178-13183, http://ir.kib.ac.cn/handle/151853/63600.
[34] Dong, Jinrun, Peng, Xingrong, Li, Lei, Lu, Shuangyang, Zhou, Lin, Qiu, Minghua. C21 steroidal glycosides with cytotoxic activities from Cynanchum otophyllum. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS[J]. 2018, 28(9): 1520-1524, http://dx.doi.org/10.1016/j.bmcl.2018.03.078.
[35] Xingrong Peng, Minghua Qiu. Meroterpenoids from Ganoderma Species:A Review of Last Five Years. 应用天然产物(英文)[J]. 2018, 8(3): 137-149, http://lib.cqvip.com/Qikan/Article/Detail?id=7105123606.
[36] Lei Li, XingRong Peng, JinRun Dong, ShuangYang Lu, XiaoNian L, Lin Zhou, MingHua Qiu. Rearranged lanostane-type triterpenoids with anti- hepatic fibrosis activities from Ganoderma applanatum. RSC ADV.,2018, 8,31287[J]. 2018, 8: 31287-31295, http://ir.kib.ac.cn/handle/151853/63598.
[37] Li, Lei, Peng, XingRong, Dong, JinRun, Lu, ShuangYang, Li, XiaoNian, Zhou, Lin, Qiu, MingHua. Rearranged lanostane-type triterpenoids with anti-hepatic fibrosis activities from Ganoderma applanatum. RSC ADVANCES[J]. 2018, 8(55): 31287-31295, [38] XingRong Peng, Xia Wang, JinRun Dong, XuJie Qin, ZhongRong Li, Han Yang, Lin Zhou, MingHua Qiu. Rare Hybrid Dimers with Anti-Acetylcholinesterase Activities from a Safflower (Carthamus tinctorius L.) Seed Oil Cake. J. AGRIC. FOOD CHEM[J]. 2017, 65: 9453-9459, http://ir.kib.ac.cn/handle/151853/63420.
[39] Yu, MuYuan, Qin, XuJie, Peng, XingRong, Wang, Xia, Tian, XiaoXue, Li, ZhongRong, Qiu, MingHua. Macathiohydantoins B-K, novel thiohydantoin derivatives from Lepidium meyenii. TETRAHEDRON[J]. 2017, 73(30): 4392-4397, http://dx.doi.org/10.1016/j.tet.2017.05.096.
[40] Peng, XingRong, Wang, Xia, Dong, JinRun, Qin, XuJie, Li, ZhongRong, Yang, Han, Zhou, Lin, Qiu, MingHua. Rare Hybrid Dimers with Anti-Acetylcholinesterase Activities from a Safflower (Carthamus tinctorius L.) Seed Oil Cake. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2017, 65(43): 9453-9459, http://dx.doi.org/10.1021/acs.jafc.7b03431.
[41] Peng, Xingrong, Li, Lei, Wang, Xia, Zhu, Guolei, Li, Zhongrong, Qiu, Minghua. Antioxidant farnesylated hydroquinones from Ganoderma capense. FITOTERAPIA[J]. 2016, 111: 18-23, http://ir.kib.ac.cn/handle/151853/26283.
[42] Peng, XingRong, Liu, JieQing, Wang, CuiFang, Han, ZhongHui, Shu, Yi, Li, XuYang, Zhou, Lin, Qiu, MingHua. Unusual prenylated phenols with antioxidant activities from Ganoderma cochlear. FOOD CHEMISTRY[J]. 2015, 171(47): 251-257, http://dx.doi.org/10.1016/j.foodchem.2014.08.127.
[43] Peng, XingRong, Liu, JieQing, Xia, JianJun, Wang, CuiFang, Li, XuYang, Deng, YuanYuan, Bao, NiMan, Zhang, ZhiRun, Qiu, MingHua. Lanostane triterpenoids from Ganoderma hainanense J. D. Zhao. PHYTOCHEMISTRY[J]. 2015, 114(SI): 137-145, http://dx.doi.org/10.1016/j.phytochem.2014.10.009.
[44] Peng, XingRong, Wang, Xia, Zhou, Lin, Hou, Bo, Zuo, ZhiLi, Qiu, MingHua. Ganocochlearic acid A, a rearranged hexanorlanostane triterpenoid, and cytotoxic triterpenoids from the fruiting bodies of Ganoderma cochlear. RSC ADVANCES[J]. 2015, 5(115): 95212-95222, http://www.irgrid.ac.cn/handle/1471x/1029000.
[45] Peng, XingRong, Liu, JieQing, Wang, CuiFang, Li, XuYang, Shu, Yi, Zhou, Lin, Qiu, MingHua. Hepatoprotective Effects of Triterpenoids from Ganoderma cochlear. JOURNAL OF NATURAL PRODUCTS[J]. 2014, 77(4): 737-743, http://www.irgrid.ac.cn/handle/1471x/845942.
[46] Peng, XingRong, Liu, JieQing, Wan, LuoSheng, Li, XiaoNian, Yan, YuXin, Qiu, MingHua. Four New Polycyclic Meroterpenoids from Ganoderma cochlear. ORGANIC LETTERS[J]. 2014, 16(20): 5262-5265, http://www.irgrid.ac.cn/handle/1471x/915859.

科研活动

   
科研项目
( 1 ) 中药灵芝中抗 肝纤维化的新 颖芳香杂萜及其作用机制研究, 主持, 国家级, 2018-01--2020-12
( 2 ) 中药灵芝中活 性成分的挖掘, 主持, 部委级, 2019-01--2022-12
( 3 ) 基于FPRs受体的抗神经炎症活性分子的挖掘及机制研究, 主持, 省级, 2020-06--2023-05
参与会议
(1)基于 FPR2 和 UCP1 受体的灵芝抗肥 胖活性成分的挖掘及构效关系研究   中国科学院青年促进会“百草论坛”   2020-11-22
(2)灵芝中新颖化学结构的发现及其保肝功能   第九届中国民族植物学大会暨第八届亚太民族植物学论坛   2018-07-12