不对称合成

   

070303-有机化学

不对称合成，有机氟化学

2016-09--2020-07   江西师范大学   博士学位
2006-09--2009-06   温州大学   硕士学位
2002-09--2006-07   宜春学院   学士学位

研究生

博士

   

2017-07~现在, 中国科学院大连化学物理研究所, 副研究员
2011-11~2017-06,中国科学院大连化学物理研究所, 助理研究员
2009-06~2011-10,中国科学院大连化学物理研究所, 实习研究员

   

（ 1 ） 一种钯催化不对称氢化合成手性氟代胺的方法, 发明, 2014, 第 2 作者, 专利号: ZL201010238747.2
（ 2 ） 一类具有轴手性双亚砜配体及其合成方法, 发明, 2014, 第 3 作者, 专利号: ZL200910187742.9
（ 3 ） 一种不对称转移氢化合成含三个连续手性中心的四氢喹啉 的方法，, 发明, 2017, 第 2 作者, 专利号: ZL201310689984.4
（ 4 ） 一种吲哚去芳构化合成取代环丙烷化合物的 方法, 发明, 2018, 第 4 作者, 专利号: ZL201410038454.8
（ 5 ） 钯催化不对称氢化合成手 性氟代吡唑啉酮类衍生物的方法, 发明, 2019, 第 2 作者, 专利号: ZL201510036414.4
（ 6 ） 仿生催化不对称氢化合成手性含氟 炔丙胺衍生物的方法, 发明, 2018, 第 2 作者, 专利号: ZL201610050611.6
（ 7 ） 一种铱催化喹啉-3-胺不对称氢化合成手性环外胺 的方法, 发明, 2017, 第 3 作者, 专利号: ZL201310691190.1
（ 8 ） 一种钯催化不对称氢化合成手性 3-三氟甲基-3,4-二 氢喹喔啉酮的方法, 发明, 2019, 第 1 作者, 专利号: 201910080337.0

   

[1] Wang, XinWei, Chen, MuWang, Wu, Bo, Wang, Baomin, Wan, Boshun, Zhou, YongGui. Chiral phosphoric acid-catalyzed regioselective synthesis of spiro aminals with quaternary stereocenters. TETRAHEDRON LETTERS[J]. 2021, 65: http://dx.doi.org/10.1016/j.tetlet.2020.152793.
[2] Wang, XinWei, Li, Xiang, Chen, MuWang, Wu, Bo, Zhou, YongGui. Chiral Phosphoric Acid-Catalyzed Pictet-Spengler Reactions for Synthesis of 5 ',11 '-Dihydrospiroindoline-3,6 '-indolo3,2-cquinolin-2-ones Containing Quaternary Stereocenters. JOURNAL OF ORGANIC CHEMISTRY[J]. 2021, 86(9): 6897-6906, http://dx.doi.org/10.1021/acs.joc.1c00289.
[3] Chen Muwang. Rhodium(III)-Catalyzed Alkylation of 2-Arylquinazoline-4-(3H)-ones with Cyclopropanols via Directing C-H Activation and Ring Opening at Ambient Temperature. ASIAN J. ORG. CHEM.. 2021, [4] Zhao, ZiBiao, Li, Xiang, Chen, MuWang, Wu, Bo, Zhou, YongGui. Enantioselective Synthesis of Tetrahydroquinolines via One-Pot Cascade Biomimetic Reduction. CHINESE JOURNAL OF CHEMISTRY[J]. 2020, 38(12): 1691-1695, http://lib.cqvip.com/Qikan/Article/Detail?id=7103704700.
[5] 谢焕平, 吴波, 陈木旺, 余长斌, 黎红旺, 李翔, 周永贵. 方酰胺催化氮杂二烯和吡唑啉-5-酮的加成：含吡唑三芳基甲烷的不对称合成. 有机化学[J]. 2020, 40(10): 3452-3462, http://lib.cqvip.com/Qikan/Article/Detail?id=7103355116.
[6] Zhao, ZiBiao, Li, Xiang, Chen, MuWang, Zhao, Zongbao K, Zhou, YongGui. Biomimetic asymmetric reduction of benzoxazinones and quinoxalinones using ureas as transfer catalysts. CHEMICAL COMMUNICATIONS[J]. 2020, 56(53): 7309-7312, http://dx.doi.org/10.1039/d0cc03091k.
[7] Li, Xiang, Zhao, ZiBiao, Chen, MuWang, Wu, Bo, Wang, Han, Yu, ChangBin, Zhou, YongGui. Palladium-catalyzed asymmetric hydrogenation of 2-aryl cyclic ketones for the synthesis of trans cycloalkanols through dynamic kinetic resolution under acidic conditions. CHEMICAL COMMUNICATIONS[J]. 2020, 56(43): 5815-5818, https://www.webofscience.com/wos/woscc/full-record/WOS:000537959100019.
[8] Wang, Jie, Zhu, ZhouHao, Chen, MuWang, Chen, QingAn, Zhou, YongGui. Catalytic Biomimetic Asymmetric Reduction of Alkenes and Imines Enabled by Chiral and Regenerable NAD(P)H Models. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2019, 58(6): 1813-1817, http://cas-ir.dicp.ac.cn/handle/321008/165974.
[9] Wang, XinWei, Chen, MuWang, Wu, Bo, Wang, Baomin, Zhou, YongGui. Chiral Phosphoric Acid-Catalyzed Synthesis of Fluorinated 5,6-Dihydroindolo1,2-cquinazolines with Quaternary Stereocenters. JOURNAL OF ORGANIC CHEMISTRY[J]. 2019, 84(12): 8300-8308, [10] Yu, ChangBin, Song, Bo, Chen, MuWang, Shen, HongGang, Zhou, YongGui. Construction of Multiple-Substituted Chiral Cyclohexanes through Hydrogenative Desymmetrization of 2,2,5-Trisubstituted 1,3-Cyclohexanediones. ORGANIC LETTERS[J]. 2019, 21(23): 9401-9404, https://www.webofscience.com/wos/woscc/full-record/WOS:000502163300026.
[11] Chen, MuWang, Deng, Zhihong, Yang, Qin, Huang, Jian, Peng, Yiyuan. Enantioselective synthesis of trifluoromethylated dihydroquinoxalinones via palladium-catalyzed hydrogenation. ORGANIC CHEMISTRY FRONTIERS[J]. 2019, 6(6): 746-750, [12] Chen, MuWang, Yang, Qin, Deng, Zhihong, Ding, Qiuping, Peng, Yiyuan. Synthesis of Chiral beta-Fluoroalkyl beta-Amino Acid Derivatives via Palladium-Catalyzed Hydrogenation. JOURNAL OF ORGANIC CHEMISTRY[J]. 2019, 84(16): 10371-10379, https://www.webofscience.com/wos/woscc/full-record/WOS:000481979200045.
[13] Feng, GuangShou, Shi, Lei, Meng, FanJie, Chen, MuWang, Zhou, YongGui. Iridium-Catalyzed Asymmetric Hydrogenation of 4,6-Disubstituted 2-Hydroxypyrimidines. ORGANIC LETTERS[J]. 2018, 20(20): 6415-6419, http://www.corc.org.cn/handle/1471x/2373129.
[14] Liu, Cong, Shen, HongQiang, Chen, MuWang, Zhou, YongGui. C-2-Symmetric Hindered "Sandwich" Chiral N-Heterocyclic Carbene Precursors and Their Transition Metal Complexes: Expedient Syntheses, Structural Authentication, and Catalytic Properties. ORGANOMETALLICS[J]. 2018, 37(21): 3756-3769, http://www.corc.org.cn/handle/1471x/2373038.
[15] Hu ShuBo, Chen MuWang, Zhai XiaoYong, Zhou YongGui. Synthesis of Tetrahydropyrrolo/indolo1,2-apyrazines by Enantioselective Hydrogenation of Heterocyclic Imines. ACTA CHIMICA SINICA[J]. 2018, 76(2): 103-106, http://cas-ir.dicp.ac.cn/handle/321008/169116.
[16] Hu ShuBo, Chen MuWang, Zhai XiaoYong, Zhou YongGui. Synthesis of Tetrahydropyrrolo/indolo1,2-apyrazines by Enantioselective Hydrogenation of Heterocyclic Imines. ACTA CHIMICA SINICA[J]. 2018, 76(2): 103-106, http://cas-ir.dicp.ac.cn/handle/321008/169116.
[17] Song, Bo, Chen, MuWang, Zhou, YongGui. Synthesis of chiral sultams with two adjacent stereocenters via palladium-catalyzed dynamic kinetic resolution. ORGANICCHEMISTRYFRONTIERS[J]. 2018, 5(7): 1113-1117, http://cas-ir.dicp.ac.cn/handle/321008/169136.
[18] Chen, MuWang, Yang, Qin, Deng, Zhihong, Zhou, Yirong, Ding, Quping, Peng, Yiyuan. Organocatalytic Asymmetric Reduction of Fluorinated Alkynyl Ketimines. JOURNAL OF ORGANIC CHEMISTRY[J]. 2018, 83(15): 8688-8694, https://www.webofscience.com/wos/woscc/full-record/WOS:000441112900106.
[19] Feng, GuangShou, Chen, MuWang, Shi, Lei, Zhou, YongGui. Facile Synthesis of Chiral Cyclic Ureas through Hydrogenation of 2-Hydroxypyrimidine/Pyrimidin-2(1H)-one Tautomers. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2018, 57(20): 5853-5857, http://cas-ir.dicp.ac.cn/handle/321008/167148.
[20] Chen, MuWang, Ji, Yue, Wang, Jie, Chen, QingAn, Shi, Lei, Zhou, YongGui. Asymmetric Hydrogenation of Isoquinolines and Pyridines Using Hydrogen Halide Generated in Situ as Activator. ORGANIC LETTERS[J]. 2017, 19(18): 4988-4991, http://cas-ir.dicp.ac.cn/handle/321008/150166.
[21] Song, Bo, Yu, ChangBin, Ji, Yue, Chen, MuWang, Zhou, YongGui. Synthesis of chiral sultams via palladiu-mcatalyzed intramolecular asymmetric reductive amination. CHEMICAL COMMUNICATIONS[J]. 2017, 53(10): 1704-1707, http://cas-ir.dicp.ac.cn/handle/321008/169586.
[22] Ji, Yue, Feng, GuangShou, Chen, MuWang, Shi, Lei, Du, Haifeng, Zhou, YongGui. Iridium-catalyzed asymmetric hydrogenation of cyclic iminium salts. ORGANIC CHEMISTRY FRONTIERS[J]. 2017, 4(6): 1125-1129, http://cas-ir.dicp.ac.cn/handle/321008/151911.
[23] Chen, MuWang, Wu, Bo, Chen, ZhangPei, Shi, Lei, Zhou, YongGui. Synthesis of Chiral Fluorinated Propargylamines via Chemoselective Biomimetic Hydrogenation. ORGANIC LETTERS[J]. 2016, 18(18): 4650-4653, http://cas-ir.dicp.ac.cn/handle/321008/170182.
[24] 高翔, 吴波, 黄文学, 陈木旺, 周永贵. Enantioselective Palladium-Catalyzed C¢H Functionalization of Indoles Using an Axially Chiral 2,2’-Bipyridine Ligand. ANGEWANDTE CHEMIE INTERNATIONAL EDITION[J]. 2016, 54: 11956-, http://cas-ir.dicp.ac.cn/handle/321008/148000.
[25] Wang, Jie, Chen, MuWang, Ji, Yue, Hu, ShuBo, Zhou, YongGui. Kinetic Resolution of Axially Chiral 5-or 8-Substituted Quinolines via Asymmetric Transfer Hydrogenation. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2016, 138(33): 10413-10416, http://www.corc.org.cn/handle/1471x/2375708.
[26] Yan, Zhong, Wu, Bo, Gao, Xiang, Chen, MuWang, Zhou, YongGui. Enantioselective Synthesis of alpha-Amino Phosphonates via Pd-Catalyzed Asymmetric Hydrogenation. ORGANIC LETTERS[J]. 2016, 18(4): 692-695, http://cas-ir.dicp.ac.cn/handle/321008/171278.
[27] Chen, ZhangPei, Hu, ShuBo, Chen, MuWang, Zhou, YongGui. Synthesis of Chiral Fluorinated Hydrazines via Pd-Catalyzed Asymmetric Hydrogenation. ORGANIC LETTERS[J]. 2016, 18(11): 2676-2679, http://cas-ir.dicp.ac.cn/handle/321008/170606.
[28] Wu, Bo, Gao, Xiang, Yan, Zhong, Chen, MuWang, Zhou, YongGui. C-H Oxidation/Michael Addition/Cyclization Cascade for Enantioselective Synthesis of Functionalized 2-Amino-4H-chromenes. ORGANIC LETTERS[J]. 2015, 17(24): 6134-6137, http://cas-ir.dicp.ac.cn/handle/321008/171568.
[29] Huang, WenXue, Wu, Bo, Gao, Xiang, Chen, MuWang, Wang, Baomin, Zhou, YongGui. Iridium-Catalyzed Selective Hydrogenation of 3-Hydroxypyridinium Salts: A Facile Synthesis of Piperidin-3-ones. ORGANIC LETTERS[J]. 2015, 17(7): 1640-1643, http://cas-ir.dicp.ac.cn/handle/321008/146168.
[30] Ji, Yue, Shi, Lei, Chen, MuWang, Feng, GuangShou, Zhou, YongGui. Concise Redox Deracemization of Secondary and Tertiary Amines with a Tetrahydroisoquinoline Core via a Nonenzymatic Process. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2015, 137(33): 10496-10499, http://cas-ir.dicp.ac.cn/handle/321008/146497.
[31] Song, Bo, Yu, ChangBin, Huang, WenXue, Chen, MuWang, Zhou, YongGui. Formal Palladium-Catalyzed Asymmetric Hydrogenolysis of Racemic N-Sulfonyloxaziridines. ORGANIC LETTERS[J]. 2015, 17(2): 190-193, http://cas-ir.dicp.ac.cn/handle/321008/145927.
[32] 陈木旺, 叶智识, 陈章培, 吴波, 周永贵. Enantioselective Synthesis of Trifluoromethyl Substituted Piperidines with Multiple Stereogeni Centers via Hydrogenation of Pyridinium Hydrochlorides. ORGANIC CHEMISTRY FRONTIERS有机化学前沿[J]. 2015, 2: 586-, http://cas-ir.dicp.ac.cn/handle/321008/148058.
[33] Ji, Yue, Chen, MuWang, Shi, Lei, Zhou, YongGui. Highly selective partial dehydrogenation of tetrahydroisoquinolines using modified Pd/C. CHINESE JOURNAL OF CATALYSIS[J]. 2015, 36(1): 33-39, http://dx.doi.org/10.1016/S1872-2067(14)60243-6.
[34] Wu, Bo, Gao, Xiang, Chen, MuWang, Zhou, YongGui. Direct amination of 2-(1-tosylalkyl)phenols with aqueous ammonia: a metal-free synthesis of primary amines. TETRAHEDRON LETTERS[J]. 2015, 56(9): 1135-1137, http://dx.doi.org/10.1016/j.tetlet.2015.01.078.
[35] 姬悦, 陈木旺, 时磊, 周永贵. Highly Selective Partial Dehydrogenation of Tetrahydroisoquinolines Using Modified Pd/C. CHINESE JOURNAL OF CATALYSIS催化学报[J]. 2015, 36: 33-, http://cas-ir.dicp.ac.cn/handle/321008/148060.
[36] Ji, Yue, Chen, MuWang, Shi, Lei, Zhou, YongGui. Highly selective partial dehydrogenation of tetrahydroisoquinolines using modified Pd/C. CHINESE JOURNAL OF CATALYSIS[J]. 2015, 36(1): 33-39, http://dx.doi.org/10.1016/S1872-2067(14)60243-6.
[37] 姬悦, 陈木旺, 时磊, 周永贵. Pd/C促进的四氢异喹啉高选择性部分脱氢（英文）. 催化学报[J]. 2015, 36(1): 33-39, http://lib.cqvip.com/Qikan/Article/Detail?id=663442780.
[38] Chen, MuWang, Ye, ZhiShi, Chen, ZhangPei, Wu, Bo, Zhou, YongGui. Enantioselective synthesis of trifluoromethyl substituted piperidines with multiple stereogenic centers via hydrogenation of pyridinium hydrochlorides. ORGANIC CHEMISTRY FRONTIERS[J]. 2015, 2(5): 586-589, https://www.webofscience.com/wos/woscc/full-record/WOS:000364445300023.
[39] Gao, Xiang, Wu, Bo, Huang, WenXue, Chen, MuWang, Zhou, YongGui. Enantioselective Palladium-Catalyzed C-H Functionalization of Indoles Using an Axially Chiral 2,2 '-Bipyridine Ligand. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2015, 54(41): 11956-11960, https://www.webofscience.com/wos/woscc/full-record/WOS:000363396000009.
[40] Chen, ZhangPei, Chen, MuWang, Shi, Lei, Yu, ChangBin, Zhou, YongGui. Pd-catalyzed asymmetric hydrogenation of fluorinated aromatic pyrazol-5-ols via capture of active tautomers. CHEMICAL SCIENCE[J]. 2015, 6(6): 3415-3419, http://dx.doi.org/10.1039/c5sc00835b.
[41] 蔡先锋, 郭冉柠, 陈木旺, 时磊, 周永贵. Synthesis of Chiral Exocyclic Amines via Asymmetric Hydrogenation of Aromatic Quinolin-3-amines. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2014, 20(1): 7245-, http://cas-ir.dicp.ac.cn/handle/321008/144241.
[42] Cai, XianFeng, Guo, RanNing, Chen, MuWang, Shi, Lei, Zhou, YongGui. Synthesis of Chiral Exocyclic Amines by Asymmetric Hydrogenation of Aromatic Quinolin-3-amines. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2014, 20(24): 7245-7248, http://cas-ir.dicp.ac.cn/handle/321008/145735.
[43] Duan, Ying, Li, Lu, Chen, MuWang, Yu, ChangBin, Fan, HongJun, Zhou, YongGui. Homogenous Pd-Catalyzed Asymmetric Hydrogenation of Unprotected Indoles: Scope and Mechanistic Studies. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2014, 136(21): 7688-7700, http://dx.doi.org/10.1021/ja502020b.
[44] Luo, Jing, Wu, Bo, Chen, MuWang, Jiang, GuoFang, Zhou, YongGui. The Concise Synthesis of Spiro-Cyclopropane Compounds via the Dearomatization of Indole Derivatives. ORGANIC LETTERS[J]. 2014, 16(10): 2578-2581, http://cas-ir.dicp.ac.cn/handle/321008/145756.
[45] Chen, MuWang, Cai, XianFeng, Chen, ZhangPei, Shi, Lei, Zhou, YongGui. Facile construction of three contiguous stereogenic centers via dynamic kinetic resolution in asymmetric transfer hydrogenation of quinolines. CHEMICAL COMMUNICATIONS[J]. 2014, 50(83): 12526-12529, http://159.226.238.44/handle/321008/143179.
[46] Wu, Bo, Gao, Xiang, Chen, MuWang, Zhou, YongGui. A Concise Synthesis of 2-(2-Hydroxyphenyl)acetonitriles via the o-Quinone Methides Generated from 2-(1-Tosylalkyl)phenols. CHINESE JOURNAL OF CHEMISTRY[J]. 2014, 32(10): 981-984, http://cas-ir.dicp.ac.cn/handle/321008/145605.
[47] Yu, ChangBin, Huang, WenXue, Shi, Lei, Chen, MuWang, Wu, Bo, Zhou, YongGui. Asymmetric Hydrogenation via Capture of Active Intermediates Generated from Aza-Pinacol Rearrangement. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2014, 136(45): 15837-15840, http://cas-ir.dicp.ac.cn/handle/321008/144100.
[48] Wu, Bo, Chen, MuWang, Ye, ZhiShi, Yu, ChangBin, Zhou, YongGui. A Streamlined Synthesis of 2,3-Dihydrobenzofurans via the ortho-Quinone Methides Generated from 2-Alkyl-Substituted Phenols. ADVANCED SYNTHESIS & CATALYSIS[J]. 2014, 356(2-3): 383-387, http://cas-ir.dicp.ac.cn/handle/321008/145810.
[49] Chen, ZhangPei, Chen, MuWang, Guo, RanNing, Zhou, YongGui. 4,5-Dihydropyrrolo1,2-aquinoxalines: A Tunable and Regenerable Biomimetic Hydrogen Source. ORGANIC LETTERS[J]. 2014, 16(5): 1406-1409, http://cas-ir.dicp.ac.cn/handle/321008/144244.
[50] 蔡先锋, 陈木旺, 叶智识, 郭冉柠, 时磊, 李艳芹, 周永贵. Asymmetric Transfer Hydrogenation of Aromatic Nitro Compounds, 3-Nitroquinolines: A Facile Access to Cyclic Nitro Compounds with Two Contiguous Stereocenters.. CHEMISTRY AN ASIAN JOURNAL[J]. 2013, 8: 1381-, http://159.226.238.44/handle/321008/119346.
[51] Guo, RanNing, Cai, XianFeng, Shi, Lei, Ye, ZhiShi, Chen, MuWang, Zhou, YongGui. An efficient route to chiral N-heterocycles bearing a C-F stereogenic center via asymmetric hydrogenation of fluorinated isoquinolines. CHEMICAL COMMUNICATIONS[J]. 2013, 49(76): 8537-8539, http://159.226.238.44/handle/321008/137874.
[52] Cai, XianFeng, Chen, MuWang, Ye, ZhiShi, Guo, RanNing, Shi, Lei, Li, YanQin, Zhou, YongGui. Asymmetric Transfer Hydrogenation of 3-Nitroquinolines: Facile Access to Cyclic Nitro Compounds with Two Contiguous Stereocenters. CHEMISTRY-AN ASIAN JOURNAL[J]. 2013, 8(7): 1381-1385, http://159.226.238.44/handle/321008/137714.
[53] 陈木旺, 曹亮亮, 叶智识, 江国防, 周永贵. A Mild Method for Generation of o-Quinone Methide under the Basic Condition. The Facile Synthesis of trans-2,3-Dihydrobenzofurans.. CHEMICAL COMMUNICATIONS[J]. 2013, 49: 1660-, http://159.226.238.44/handle/321008/119301.
[54] 吴波, 陈木旺, 周永贵. A streamlined Synthesis of 2,3-Dihydrobenzofurans via the o-Quinone Methides Intermediates. 24th international society of heterocyclic chemistry congressnull. 2013, 141-, http://159.226.238.44/handle/321008/120085.
[55] 郭冉柠, 蔡先锋, 时磊, 叶智识, 陈木旺, 周永贵. An Efficient Route to Chiral N-Heterocycles Bearing C-F Stereogenic Center via Asymmetric Hydrogenation of Fluorinated Isoquinolines.. CHEMICAL COMMUNICATIONS[J]. 2013, 49: 8537-, http://159.226.238.44/handle/321008/119338.
[56] Chen, MuWang, Cao, LiangLiang, Ye, ZhiShi, Jiang, GuoFang, Zhou, YongGui. A mild method for generation of o-quinone methides under basic conditions. The facile synthesis of trans-2,3-dihydrobenzofurans. CHEMICAL COMMUNICATIONS[J]. 2013, 49(16): 1660-1662, http://159.226.238.44/handle/321008/137758.
[57] Ye, ZhiShi, Guo, RanNing, Cai, XianFeng, Chen, MuWang, Shi, Lei, Zhou, YongGui. Enantioselective Iridium-Catalyzed Hydrogenation of 1-and 3-Substituted Isoquinolinium Salts. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2013, 52(13): 3685-3689, http://159.226.238.44/handle/321008/119173.
[58] 陈章培, 叶智识, 陈木旺, 周永贵. Enantioselective Synthesis of Endo-Cyclic Beta-Amino Acids with Two Contiguous Stereocenters via Hydrogenation of 3-Carbalkoxy-2-Substituted Quinolines.. SYNTHESIS[J]. 2013, 45: 3239-, http://159.226.238.44/handle/321008/119652.
[59] Chen, ZhangPei, Ye, ZhiShi, Chen, MuWang, Zhou, YongGui. Enantioselective Synthesis of Endocyclic beta-Amino Acids with Two Contiguous Stereocenters via Hydrogenation of 3-Alkoxycarbonyl-2-Substituted Quinolines. SYNTHESIS-STUTTGART[J]. 2013, 45(23): 3239-3244, http://159.226.238.44/handle/321008/137806.
[60] Yu, ChangBin, Gao, Kai, Chen, QingAn, Chen, MuWang, Zhou, YongGui. Enantioselective Pd-catalyzed hydrogenation of tetrasubstituted olefins of cyclic beta-(arylsulfonamido)acrylates. TETRAHEDRON LETTERS[J]. 2012, 53(20): 2560-2563, http://159.226.238.44/handle/321008/143123.
[61] Ye, ZhiShi, Chen, MuWang, Chen, QingAn, Shi, Lei, Duan, Ying, Zhou, YongGui. Iridium-Catalyzed Asymmetric Hydrogenation of Pyridinium Salts. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2012, 51(40): 10181-10184, http://159.226.238.44/handle/321008/142904.
[62] Chen, MuWang, Chen, QingAn, Duan, Ying, Ye, ZhiShi, Zhou, YongGui. Asymmetric hydrogenolysis of racemic tertiary alcohols, 3-substituted 3-hydroxyisoindolin-1-ones. CHEMICAL COMMUNICATIONS[J]. 2012, 48(11): 1698-1700, http://159.226.238.44/handle/321008/138020.
[63] Duan, Ying, Chen, MuWang, Chen, QingAn, Yu, ChangBin, Zhou, YongGui. Pd-Catalyzed asymmetric hydrogenation of 3-(toluenesulfonamidoalkyl)indoles. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2012, 10(6): 1235-1238, http://dx.doi.org/10.1039/c1ob06777j.
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[65] Chen Muwang. Enantioselective Pd-Catalyzed Hydrogenation of Fluorinated Imines: Facile Access to Chiral Fluorinated Amines.. Org. Lett.. 2011, [66] 王躲生, 唐杰, 周永贵, 陈木旺, 余长斌, 段英, 江国防. Dehydration triggered asymmetric hydrogenation of 3-(a-hydroxyalkyl)indoles.. CHEMICAL SCIENCE[J]. 2011, 待补充(待补充): 803-, http://www.irgrid.ac.cn/handle/1471x/456779.
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[68] Chen, QingAn, Chen, MuWang, Yu, ChangBin, Shi, Lei, Wang, DuoSheng, Yang, Yan, Zhou, YongGui. Biomimetic Asymmetric Hydrogenation: In Situ Regenerable Hantzsch Esters for Asymmetric Hydrogenation of Benzoxazinones. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2011, 133(41): 16432-16435, http://www.irgrid.ac.cn/handle/1471x/456791.
[69] Duan, Ying, Chen, MuWang, Ye, ZhiShi, Wang, DuoSheng, Chen, QingAn, Zhou, YongGui. An Enantioselective Approach to 2,3-Disubstituted Indolines through Consecutive Bronsted Acid/Pd-Complex-Promoted Tandem Reactions. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2011, 17(26): 7193-7197, http://dx.doi.org/10.1002/chem.201100576.
[70] Chen, QingAn, Dong, Xiang, Chen, MuWang, Wang, DuoSheng, Zhou, YongGui, Li, YuXue. Highly Effective and Diastereoselective Synthesis of Axially Chiral Bis-sulfoxide Ligands via Oxidative Aryl Coupling. ORGANIC LETTERS[J]. 2010, 12(9): 1928-1931, http://159.226.238.44/handle/321008/103493.
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（ 1 ） 索利那新不对称合成新工艺, 主持, 市地级, 2020-08--2022-07
（ 2 ） 百济（S）-BG-10的不对称合成工业, 参与, 院级, 2020-06--2021-12