Prof. Min Shi, Shanghai Institute of Organic Chemistry
Telephone: 021-54925137
Address: Fenglin Lu 354, Building No. 1, Room 406
Postcode: 200032

Research Areas

Organometallic Chemistry (OMCOS), Asymmetric Organocatalysis, Fixation of CO2, Green Chemistry, Organic Synthesis 




Ph.D.: April 1988—March 1991, Department of Chemical Process Engineering, Faculty of Engineering, Osaka University, Japan.


Master: October 1985—March 1988. Department of Chemistry, Faculty of Engineering, Gifu University, Japan.


Bachelor: August 1980—August 1984, Department of Chemistry, Faculty of Engineering, Institute of Chemical Engineering of East China, China.





Professor and Group Leader: April 1998-Now, State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry (SIOC). 


ERATO Researcher: December 1996—March 1998, Inoue Photochirogenesis Project, Japan Science and Technology Corporation (JST) and worked on the photo-induced asymmetric reaction and synthesis.


Postdoctor: October 1995—December 1996, University of Oklahoma, Department of Chemistry and Biochemistry, U.S.A., Prof. Kenneth M. Nicholas’s research group and worked on the fixation of CO2 using transition metal complexes.


Research Assistant: April 1993—October 1995, Research Laboratory of Synthetic Organic Chemistry, Gifu Pharmaceutical   University, Japan and worked on the asymmetric synthesis, drug design, and molecular recognition.

Teaching Experience
Organic Chemistry and Photoorganic Chemistry

Honors & Distinctions

Shanghai Natural Scientific Award:

zwitterionic ion directed organic synthesis


Selected Publications:


1. Multifunctional Chiral Phosphine Organocatalysts in Catalytic Asymmetric Morita-Baylis-Hillman and Related Reactions.

Yin Wei and Min Shi,* Acc. Chem. Res. 2010, 43, 1005-1018.


2. Synthesis of Functionalized Polycyclic Compounds by Rh(I)-catalyzed Intramolecular Cycloaddition of Yne-VDCPs and Ene-VDCPs.

Bei-Li Lu, Min Shi,* Angew. Chem., Int. Ed. 2011, 50, 12027-12031.


3. Gold(I)-Catalyzed Cycloisomerization of 1,6-Diynes Containing Propargylic Ester and Arenyne: Synthesis of 2,3-Disubstituted 3-Pyrroline Derivatives.

Di-Han Zhang, Liang-Feng Yao, Yin Wei and Min Shi,* Angew. Chem., Int. Ed. 2011, 50, 2583-2588.


4. Rapid generation of molecular complexity in the Lewis or Brønsted acid-mediated reactions of methylenecyclopropanes.

Min Shia*, Jian-Mei Lub, Yin Weia and Li-Xiong Shaob* Acc. Chem. Res. 2012, 45, 641-652.


5. Enantioselective Synthesis of Highly Functionalized Phosphonate Substituted Pyrans or Dihydropyrans: Asymmetric [4+2] Cycloaddition of b,g-Unsaturated a-Ketophosphonates with Allenic Esters.

Cheng-Kui Pei,a Yu Jiang,a Yin Weib* and Min Shi,a,b* Angew. Chem., Int. Ed. 2012, 51, 11328-11332.


6. Gold-Catalyzed Intramolecular Regio- and Enantioselective Cycloisomerization of 1,1-Bisindolyl-5-alkynes.

Long Huang,a Hai-Bin Yang,a Di-Han Zhang,a Zhen Zhang,b Xiang-Ying Tang,a Qin Xu,b* and Min Shi,a,b* Angew. Chem., Int. Ed. 2013, 52, 6767-6771. 


7. Gold-Catalyzed Cyclization of 1-(Indol-3-yl)-3-alkyn-1-ols: Facile Synthesis of Diversified Carbazoles.

Zhen Zhang,a Xiangying Tang,a* Qin Xub* and Min Shi,a,b* Chem. Eur. J. 2013, 19, 10625-10631.


8. Recent Advances in Organocatalytic Asymmetric Morita-Baylis-Hillman/aza-Morita-Baylis-Hillman Reactions.

Yin Wei, Min Shi,* Chem. Rev. 2013, 113, 6659-6690.


9. Enantioselective Desymmetrization of Bicyclic Hydrazines using C2-Symmetric N-Heterocyclic Carbene (NHC) Palladium Complex as Catalyst.

Peng Gu,a Qin Xu,a* and Min Shi,a,b* Organometallics 2013, 33, 7575-7579.


10. Phosphine-Promoted Cyclization of Dicyclopropenones.

Jin-Ming Yang,a Xiang-Ying Tang,b Yin Weib* and Min Shi,a,b* Adv. Synth. Catal. 2013, 355, 3545-3552.


11. Rhodium(II)-Catalyzed Intramolecular Annulation of 1-Sulfonyl-1,2,3-triazoles with Pyrrole and Indole rings: Facile Synthesis of N-bridgehead Azepine Skeletons.

Jin-Ming Yang, Cheng-Zhi Zhu, Xiang-Ying Tang,‡* and Min Shi,†,‡,* Angew. Chem., Int. Ed. 2014, 53, 5142-5146.


12. RhII-Catalyzed Intramolecular Cycloisomerizations of Methylenecyclopropanes with N-sulfonyl 1,2,3-triazoles.

Kai Chen, Zi-Zhong Zhu, Yong-Sheng Zhang, Xiang-Ying Tang,‡,* and Min Shi†,‡, Angew. Chem., Int. Ed. 2014, 53, 6645-6649.


13. One-pot Tandem Diastereoselective and Enantioselective Synthesis of Functionalized Oxindole-Fused Spiropyrazolidine Frameworks.

Liang-Yong Mei, Xiang-Ying Tang,‡* and Min Shi,†,‡,* Chem. Eur. J. 2014, 20, 13136-13142. 


14. Gold-catalyzed tandem reactions of methylenecyclopropanes and vinylidenecyclopropanes.

Di-Han Zhang, Xiang-Ying Tang,* Min Shi,* Acc. Chem. Res. 2014, 47, 913-924.


15. Gold-Catalyzed Cycloisomerization of Yne-Vinylidenecyclopropanes: VDCP as a 3-Carbon Synthon for [3+2] Cycloaddition.

Wei Yuan, Xiangying Tang, Yin Wei,* Min Shi,* Chem. Eur. J. 2014, 20, 3198-3204.


16. Phosphine-catalyzed Asymmetric [4+1] Annulations of Activated α,β-Unsaturated Ketones with Morita-Baylis-Hillman Carbonates: Enantioselective Synthesis of Spirooxindoles Containing Two Adjacent Quaternary Stereocenters.

Fang-Le Hu, Yin Wei and Min Shi,* Chem. Commun. 2014, 50, 8912-8914.


17. Catalyst Dependent Divergent Synthesis of Pyrroles from 3-Alkynyl Imine Derivatives: Non-carbonylative and Carbonylative Approach.

Gen-Qiang Chen, Xiao-Nan Zhang, Yin Wei, Xiang-Ying Tang,* and Min Shi,* Angew. Chem., Int. Ed. 2014, 53, 8492-8497.


18. Phosphine-Catalyzed Annulations of 4,4-Dicyano-2-Methylenebut-3-Enoates with Maleimides and Maleic Anhydride.

Xiao-Nan Zhang, Gen-Qiang Chen, Xiang-Ying Tang, Yin Wei, and Min Shi,* Angew. Chem., Int. Ed. 2014, 53, 10768-10773.


19. Catalyst-dependent Stereodivergent and Regioselective Synthesis of Indole-fused Heterocycles through Formal Cycloadditions of Indolyl-allenes.

Liang-Yong Mei, Yin Wei, Xiang-Ying Tang,* Min Shi,† ‡* J. Am. Chem. Soc. 2015, 137, 8131-8137.


20. Gold(I)-Catalyzed Cycloisomerization of Vinylidenecyclopropane-enes via Carbene or non-Carbene Processes.

De-Yao Li, Yin Wei, Ilan Marek, Xiangying Tang,* Min Shi,* Chem. Sci. 2015, 7, 5519-5525.


21. Chiral Phosphine-Catalyzed Tunable Cycloaddition Reactions of Allenoates with Benzofuranone Derived Olefins for Highly Regio-, Diastereo- and Enantioselective Synthesis of Spiro-Benzofuranones.

De Wang, Guo-Peng Wang, Yao-Liang Sun,Shou-Fei Zhu, Yin Wei,* Qi-Lin Zhou,* Min Shi,* Chem. Sci. 2015, 7, 7319-7325.


22. Divergent Reaction Pathways in Gold Catalyzed Cycloisomerization of 1,5-enynes Containing a Cyclopropane: Dramatic Ortho Substituent and Temperature Effects.

Gen-Qiang Chen, Wei Fang, Yin Wei,* Xiang-Ying Tang,* and Min Shi,* Chem. Sci. 2016, 7, 4318-4328.


23. Metal-Free Cross-coupling of Arylboronic acid and Derivatives with DAST-type reagents for the Direct Access of Diverse Aromatic Sulfinamides and Sulfonamides.

Qiang Wang, Xiang-Ying Tang,* and Min Shi,* Angew. Chem., Int. Ed. 2016, 55, 10811-10815.

Research Interests

Total synthesis of natural product, Developing new chiral ligands or organocatalysts in catalytic asymmetric synthesis, Fixation of CO2 using transition metal catalyst.


East China University of Science and Technology

The Mallat Family Laboratory of Organic Chemistry, Schulich Faculty of Chemistry and Lise Meitner-Minerva Center for Computational Quantum Chemistry, Technion-Israel Institute of Technology, Technion City, Haifa 32000 Israel.



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