基本信息
马俊英 女 南海海洋研究所
电子邮件：Majunying@scsio.ac.cn
通信地址：广州市海珠区新港西路164号
邮政编码：510301
电子邮件：Majunying@scsio.ac.cn
通信地址：广州市海珠区新港西路164号
邮政编码：510301
招生信息
招生专业
071005-微生物学
071010-生物化学与分子生物学
071020-生物技术与医药
071010-生物化学与分子生物学
071020-生物技术与医药
招生方向
海洋微生物
海洋微生物活性次级代谢产物的生物合成
生物技术
海洋微生物活性次级代谢产物的生物合成
生物技术
教育背景
2004-09--2009-06 华南农业大学 博士学位
2000-09--2004-06 河南农业大学 学士学位
2000-09--2004-06 河南农业大学 学士学位
工作经历
工作简历
2011-12--今 中国科学院南海海洋研究所 副研究员
2009-07--2011-11 中国科学院南海海洋研究所 助理研究员
2009-07--2011-11 中国科学院南海海洋研究所 助理研究员
专利与奖励
奖励信息
（1） 广东省优秀博士学位论文，省级，2010
（2） 华南农业大学优秀博士学位论文，研究所（学校）级，2009
（2） 华南农业大学优秀博士学位论文，研究所（学校）级，2009
出版信息
发表论文
[1] Mar. Drugs. 2024,
[2] Mar. Drugs. 2024,
[3] ACS Synth. Biol.. 2024,
[4] J Fungi (Basel). 2023,
[5] ACS Synth. Biol.. 2022,
[6] J Fungi (Basel). 2022,
[7] Front Chem. 2021,
[8] J. Nat. Prod.. 2020,
[9] J. Nat. Prod.. 2020,
[10] Appl. Microbiol. Biotechnol.. 2020,
[11] Mar. Drugs. 2020,
[12] J. Hematol. Oncol.. 2019,
[13] Mar. Drugs. 2019,
[14] Metab. Eng. Commun.. 2019,
[15] Org. Lett. 2019,
[16] Li, Yan, Zhang, Chunyan, Liu, Chengxiong, Ju, Jianhua, Ma, Junying. Genome Sequencing of Streptomyces atratus SCSIOZH16 and Activation Production of Nocardamine via Metabolic Engineering. FRONTIERS IN MICROBIOLOGY[J]. 2018, 9: https://doaj.org/article/4e300bf75e7b40f6859ee9de46d51ea2.
[17] 鞠建华. Enzymatic synthesis of GDP-b-L-fucofuranose by MtdL and Hyg20. Org. Lett.. 2018,
[18] Junying Ma, Hongbo Huang, Yunchang Xie, Zhiyong Liu, Jin Zhao, Chunyan Zhang, Yanxi Jia, Yun Zhang, Hua Zhang, Tianyu Zhang, Jianhua Ju. Biosynthesis of ilamycins featuring unusual building blocks and engineered production of enhanced anti-tuberculosis agents. NATURE COMMUNICATIONS[J]. 2017, 8(1): https://doaj.org/article/2545b0357ffc46139661ca403feacb2e.
[19] Gui, Chun, Li, Qinglian, Mo, Xuhua, Qin, Xiangjing, Ma, Junying, Ju, Jianhua. Discovery of a New Family of Dieckmann Cyclases Essential to Tetramic Acid and Pyridone-Based Natural Products Biosynthesis. ORGANICLETTERS[J]. 2015, 17(3): 628-631, http://ir.scsio.ac.cn/handle/344004/14863.
[20] Xie, Yunchang, Li, Qinglian, Song, Yongxiang, Ma, Junying, Ju, Jianhua. Involvement of SgvP in Carbon-Sulfur Bond Formation during Griseoviridin Biosynthesis. CHEMBIOCHEM[J]. 2014, 15(8): 1183-1189, https://www.webofscience.com/wos/woscc/full-record/WOS:000337582200017.
[21] Wang, Bo, Song, Yongxiang, Luo, Minghe, Chen, Qi, Ma, Junying, Huang, Hongbo, Ju, Jianhua. Biosynthesis of 9-Methylstreptimidone Involves a New Decarboxylative Step for Polyketide Terminal Diene Formation. ORGANIC LETTERS[J]. 2013, 15(6): 1278-1281, https://www.webofscience.com/wos/woscc/full-record/WOS:000316520300032.
[22] Qi Chen, Changtao Ji, Dr. Yongxiang Song, Dr. Hongbo Huang, Dr. Junying Ma, Dr. Xinpeng Tian, Prof. Dr. Jianhua Ju. Discovery of McbB, an Enzyme Catalyzing the β‐Carboline Skeleton Construction in the Marinacarboline Biosynthetic Pathway. ANGEWANDTE CHEMIE INTERNATIONAL EDITION. 2013,
[23] 鞠建华. Δ11,12 double bond formation in tirandamycin biosynthesis is atypically catalyzed by TrdE, a glycoside hydrolase family enzyme.. 2012,
[24] Junying Ma, JianHua Liu, Luchao Lv, Zhiyong Zong, Yan Sun, Hongqing Zheng, ZhangLiu Chen, ZhenLing Zeng. Characterization of Extended-Spectrum β-Lactamase Genes Found among Escherichia coli Isolates from Duck and Environmental Samples Obtained on a Duck Farm. APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 2012, 78(10): 3668-3673,
[25] Ma Junying. Characterization of a single gene cluster that is responsible for methylpendolmycin and pendolmycin biosynthesis in the deep sea bacterium Marinactinospora thermotolerans.. ChemBioChem. 2012,
[26] Ma, Junying, Wang, Zhongwen, Huang, Hongbo, Luo, Minghe, Zuo, Dianguang, Wang, Bo, Sun, Aijun, Cheng, YiQiang, Zhang, Changsheng, Ju, Jianhua. Biosynthesis of Himastatin: Assembly Line and Characterization of Three Cytochrome P450 Enzymes Involved in the Post-tailoring Oxidative Steps. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2011, 50(34): 7797-7802, https://www.webofscience.com/wos/woscc/full-record/WOS:000294175700010.
[27] Ma, Junying, Zeng, Zhenling, Chen, Zhangliu, Xu, Xiaogang, Wang, Xiaoying, Deng, Yuting, Lue, Dianhong, Huang, Liangzong, Zhang, Yunyuan, Liu, Jianhua, Wang, Minggui. High Prevalence of Plasmid-Mediated Quinolone Resistance Determinants qnr, aac(6 ')-Ib-cr, and qepA among Ceftiofur-Resistant Enterobacteriaceae Isolates from Companion and Food-Producing Animals. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY[J]. 2009, 53(2): 519-524, http://dx.doi.org/10.1128/AAC.00886-08.
[2] Mar. Drugs. 2024,
[3] ACS Synth. Biol.. 2024,
[4] J Fungi (Basel). 2023,
[5] ACS Synth. Biol.. 2022,
[6] J Fungi (Basel). 2022,
[7] Front Chem. 2021,
[8] J. Nat. Prod.. 2020,
[9] J. Nat. Prod.. 2020,
[10] Appl. Microbiol. Biotechnol.. 2020,
[11] Mar. Drugs. 2020,
[12] J. Hematol. Oncol.. 2019,
[13] Mar. Drugs. 2019,
[14] Metab. Eng. Commun.. 2019,
[15] Org. Lett. 2019,
[16] Li, Yan, Zhang, Chunyan, Liu, Chengxiong, Ju, Jianhua, Ma, Junying. Genome Sequencing of Streptomyces atratus SCSIOZH16 and Activation Production of Nocardamine via Metabolic Engineering. FRONTIERS IN MICROBIOLOGY[J]. 2018, 9: https://doaj.org/article/4e300bf75e7b40f6859ee9de46d51ea2.
[17] 鞠建华. Enzymatic synthesis of GDP-b-L-fucofuranose by MtdL and Hyg20. Org. Lett.. 2018,
[18] Junying Ma, Hongbo Huang, Yunchang Xie, Zhiyong Liu, Jin Zhao, Chunyan Zhang, Yanxi Jia, Yun Zhang, Hua Zhang, Tianyu Zhang, Jianhua Ju. Biosynthesis of ilamycins featuring unusual building blocks and engineered production of enhanced anti-tuberculosis agents. NATURE COMMUNICATIONS[J]. 2017, 8(1): https://doaj.org/article/2545b0357ffc46139661ca403feacb2e.
[19] Gui, Chun, Li, Qinglian, Mo, Xuhua, Qin, Xiangjing, Ma, Junying, Ju, Jianhua. Discovery of a New Family of Dieckmann Cyclases Essential to Tetramic Acid and Pyridone-Based Natural Products Biosynthesis. ORGANICLETTERS[J]. 2015, 17(3): 628-631, http://ir.scsio.ac.cn/handle/344004/14863.
[20] Xie, Yunchang, Li, Qinglian, Song, Yongxiang, Ma, Junying, Ju, Jianhua. Involvement of SgvP in Carbon-Sulfur Bond Formation during Griseoviridin Biosynthesis. CHEMBIOCHEM[J]. 2014, 15(8): 1183-1189, https://www.webofscience.com/wos/woscc/full-record/WOS:000337582200017.
[21] Wang, Bo, Song, Yongxiang, Luo, Minghe, Chen, Qi, Ma, Junying, Huang, Hongbo, Ju, Jianhua. Biosynthesis of 9-Methylstreptimidone Involves a New Decarboxylative Step for Polyketide Terminal Diene Formation. ORGANIC LETTERS[J]. 2013, 15(6): 1278-1281, https://www.webofscience.com/wos/woscc/full-record/WOS:000316520300032.
[22] Qi Chen, Changtao Ji, Dr. Yongxiang Song, Dr. Hongbo Huang, Dr. Junying Ma, Dr. Xinpeng Tian, Prof. Dr. Jianhua Ju. Discovery of McbB, an Enzyme Catalyzing the β‐Carboline Skeleton Construction in the Marinacarboline Biosynthetic Pathway. ANGEWANDTE CHEMIE INTERNATIONAL EDITION. 2013,
[23] 鞠建华. Δ11,12 double bond formation in tirandamycin biosynthesis is atypically catalyzed by TrdE, a glycoside hydrolase family enzyme.. 2012,
[24] Junying Ma, JianHua Liu, Luchao Lv, Zhiyong Zong, Yan Sun, Hongqing Zheng, ZhangLiu Chen, ZhenLing Zeng. Characterization of Extended-Spectrum β-Lactamase Genes Found among Escherichia coli Isolates from Duck and Environmental Samples Obtained on a Duck Farm. APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 2012, 78(10): 3668-3673,
[25] Ma Junying. Characterization of a single gene cluster that is responsible for methylpendolmycin and pendolmycin biosynthesis in the deep sea bacterium Marinactinospora thermotolerans.. ChemBioChem. 2012,
[26] Ma, Junying, Wang, Zhongwen, Huang, Hongbo, Luo, Minghe, Zuo, Dianguang, Wang, Bo, Sun, Aijun, Cheng, YiQiang, Zhang, Changsheng, Ju, Jianhua. Biosynthesis of Himastatin: Assembly Line and Characterization of Three Cytochrome P450 Enzymes Involved in the Post-tailoring Oxidative Steps. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2011, 50(34): 7797-7802, https://www.webofscience.com/wos/woscc/full-record/WOS:000294175700010.
[27] Ma, Junying, Zeng, Zhenling, Chen, Zhangliu, Xu, Xiaogang, Wang, Xiaoying, Deng, Yuting, Lue, Dianhong, Huang, Liangzong, Zhang, Yunyuan, Liu, Jianhua, Wang, Minggui. High Prevalence of Plasmid-Mediated Quinolone Resistance Determinants qnr, aac(6 ')-Ib-cr, and qepA among Ceftiofur-Resistant Enterobacteriaceae Isolates from Companion and Food-Producing Animals. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY[J]. 2009, 53(2): 519-524, http://dx.doi.org/10.1128/AAC.00886-08.
科研活动
科研项目
（1） 抗肿瘤抗生素marthiapeptide A 的生物合成机制及其工程改造，主持，省级，2014-01--2016-12
（2） 抗菌环肽类抗生素ilamycin的生物合成研究(20872152)，主持，国家级，2013-01--2016-12
（3） 中国科学院创新促进会会员专项基金，主持，院级级，2013-01--2016-12
（4） 海洋放线菌来源的β-卡啉生物碱Marinocarboline A-F的生物合成机制研究 (SQ201，主持，院级级，2011-10--2013-12
（5） 抗肿瘤抗生素海沟霉素A和B的生物合成及其功能基因研究（31000051） ，主持，国家级，2011-01--2013-12
（2） 抗菌环肽类抗生素ilamycin的生物合成研究(20872152)，主持，国家级，2013-01--2016-12
（3） 中国科学院创新促进会会员专项基金，主持，院级级，2013-01--2016-12
（4） 海洋放线菌来源的β-卡啉生物碱Marinocarboline A-F的生物合成机制研究 (SQ201，主持，院级级，2011-10--2013-12
（5） 抗肿瘤抗生素海沟霉素A和B的生物合成及其功能基因研究（31000051） ，主持，国家级，2011-01--2013-12