基本信息
卢珊 女 硕导 中国科学院福建物质结构研究所
电子邮件: lushan@fjirsm.ac.cn
通信地址: 中国福州闽侯上街高新大道8号中科院海西研究院1号楼1212
邮政编码:
研究领域
稀土介孔功能材料的制备与生物应用
教育背景
2006-09--2011-06 北京化工大学 博士研究生2002-09--2006-06 北京化工大学 本科
工作经历
2021-12~现在, 中科院福建物构所, 研究员
2014-12~2021-12 中科院福建物构所, 副研究员
2011-07~2014-12,中科院福建物构所, 助理研究员
专利与奖励
奖励信息
(1) 2018年度中国稀土科学技术奖基础研究类一等奖, 一等奖, 其他, 2018(2) 第十三届福建省自然科学优秀学术论文二等奖, 二等奖, 省级, 2018
专利成果
[1] 李幸俊, 刘凡, 陈学元, 卢珊, 李卓. 一种基于AIE分子-稀土无机纳米晶的纳米复合材料及其用途. 202310375161.8, 2023-04-10.[2] 李幸俊, 冯艳辉, 陈学元, 卢珊, 商晓颖. 不同形貌的ZIF-8微米晶及其与上转换纳米颗粒复合物的制备方法. 202210373682.5, 2022-04-06.[3] 卢珊, 刘若湄, 陈学元, 李卓, 李幸俊. 一种近红外光响应型药物递送系统及其制备方法和应用. 202210205779.5, 2022-02-25.[4] 陈学元, 卢珊, 柯建熙, 李幸俊, 李卓. 基于上转换荧光探针同时检测细胞内次氯酸根离子和锌离子的方法. 202010121122.1, 2020-02-26.[5] 李幸俊, 陈学元, 周山勇, 李仁富, 卢珊, 郑伟, 解子人. 一种稀土-有机框架纳米荧光探针及其制备方法和应用. CN: CN112646191A, 2021-04-13.[6] 卢珊, 陈学元, 柯建熙, 商晓颖, 刘*, 李幸俊, 宋晓荣. 一种基于双激发比率型上转换荧光探针的胞内检测方法. CN: CN112444505A, 2021-03-05.[7] 刘龑, 陈学元, 柯建熙, 卢珊, 黄萍, 周山勇. 一种基于酶诱导磷酸根离子激活的近红外荧光免疫分析试剂盒及检测方法. ZL 2018 1 1565498.0, 2018-12-20.[8] 陈学元, 徐金, 涂大涛, 郑伟, 卢珊. 稀土氟氧化物纳米材料及其制备方法和应用. 中国: CN105505392B, 2018-02-02.[9] 陈学元, 卢珊, 涂大涛, 李幸俊, 李仁富. 一种中空核壳结构稀土上转换发光纳米球及其制备方法和用途. CN: CN105295919A, 2016-02-03.[10] 陈学元, 卢珊, 涂大涛. 一种肿瘤靶向的中空核壳结构纳米诊疗剂及其制备方法和应用. CN: CN104784707A, 2015-07-22.[11] 何静, 卢珊. 一种多级结构固定化酶的制备方法. CN: CN101974509A, 2011-02-16.[12] 卢珊, 刘若湄, 陈学元, 李卓, 李幸俊. 一种近红外光响应型药物递送系统及其制备方法和应用. CN: CN116688140A, 2023-09-05.[13] 李幸俊, 陈学元, 周山勇, 李仁富, 卢珊, 郑伟, 解子人. 一种稀土-有机框架纳米荧光探针及其制备方法和应用. CN: CN112646191B, 2022-03-22.[14] 卢珊, 陈学元, 柯建熙, 商晓颖, 刘䶮, 李幸俊, 宋晓荣. 一种基于双激发比率型上转换荧光探针的胞内检测方法. CN: CN112444505B, 2022-02-18.[15] 何静, 卢珊. 一种结构可控的定向式生长介孔吸附材料及其制备方法. CN: CN101559347A, 2009-10-21.
出版信息
发表论文
[1] 周武森, 龚佳成, 卢珊, 陈学元. Cypate-Sensitized Upconversion Nanoprobes for Intracellular and In-Vivo ATP Ratiometric Detection. Chemical Engineering Journal[J]. 2024, [2] 龚佳成, 李卓, 卢珊, 陈学元. Photothermal lanthanide nanomaterials: from fundamentals to theranostic applications. BMEMat[J]. 2024, 2: e12088-, [3] 李卓, 卢珊, 陈学元. Customized Lanthanide Nanobiohybrids for Noninvasive Precise Phototheranostics of Pulmonary Biofilm Infection. ACS Nano[J]. 2024, 18(18): 11837-11848, [4] Yanhui Feng, Xingjun Li, Shan Lu, Renfu Li, Zhongliang Gong, Xiaoying Shang, Yifan Pei, Wei Zheng, Datao Tu, Xueyuan Chen. Modulator-Directed Assembly of Hybrid Composites Based on Metal-Organic Frameworks and Upconversion Nanoparticles. Nano Research[J]. 2023, 16(1): 1482-1490, [5] Liu, Fan, Zhou, Wusen, Li, Xingjun, Li, Zhuo, Lu, Shan, Shang, Xiaoying, Tan, Chong, Hu, Ping, Chen, Zhuo, Chen, Xueyuan. AIEgen-sensitized lanthanide nanocrystals as luminescent probes for intracellular Fe3+monitoring. TALANTA[J]. 2023, 262: http://dx.doi.org/10.1016/j.talanta.2023.124729.[6] Fan Liu, Wusen Zhou, Xingjun Li, Zhuo Li, Shan Lu, Xiaoying Shang, Chong Tan, Ping Hu, Zhuo Chen, Xueyuan Chen. AIEgen-sensitized lanthanide nanocrystals as luminescent probes for intracellular Fe3+ monitoring. Talanta[J]. 2023, 262: 124729-, [7] Li, Zhuo, Lu, Shan, Li, Xingjun, Chen, Zhuo, Chen, Xueyuan. Lanthanide Upconversion Nanoplatforms for Advanced Bacteria-Targeted Detection and Therapy. ADVANCED OPTICAL MATERIALS[J]. 2023, 11(11): https://www.doi.org/10.1002/adom.202202386.[8] 刘若湄, 冯艳辉, 李卓, 卢珊, 关天用, 李幸俊, 刘䶮, 陈卓, 陈学元. A novel near-infrared responsive lanthanide upconversion nanoplatform for drug delivery based on photocleavage of cypate. Acta Chim. Sinica[J]. 2022, 80(4): 423-427, http://sioc-journal.cn/Jwk_hxxb/CN/10.6023/A22010001.[9] Li, Zhuo, Lu, Shan, Liu, Wenzhen, Dai, Tao, Ke, Jianxi, Li, Xingjun, Li, Renfu, Zhang, Yuxiang, Chen, Zhuo, Chen, Xueyuan. Synergistic Lysozyme-Photodynamic Therapy Against Resistant Bacteria based on an Intelligent Upconversion Nanoplatform. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2021, 60(35): 19201-19206, http://dx.doi.org/10.1002/anie.202103943.[10] Shan Lu, Jianxi Ke, Xingjun Li, Datao Tu, Xueyuan Chen. Luminescent nano‐bioprobes based on NIR dye/lanthanide nanoparticle composites. AGGREGATE[J]. 2021, 2(5): n/a-n/a, [11] Wei, Jiaojiao, Zheng, Wei, Huang, Ping, Gong, Zhongliang, Liu, Yan, Lu, Shan, Li, Zhuo, Chen, Xueyuan. Direct photoinduced synthesis of lead halide perovskite nanocrystals and nanocomposites. NANO TODAY[J]. 2021, 39: 101179-, http://dx.doi.org/10.1016/j.nantod.2021.101179.[12] Ke, Jianxi, Lu, Shan, Li, Zhuo, Shang, Xiaoying, Li, Xingjun, Li, Renfu, Tu, Datao, Chen, Zhuo, Chen, Xueyuan. Multiplexed intracellular detection based on dual-excitation/dual-emission upconversion nanoprobes. NANO RESEARCH[J]. 2020, 13(7): 1955-1961, http://lib.cqvip.com/Qikan/Article/Detail?id=7102716205.[13] Xie, Ziren, Li, Xingjun, Li, Renfu, Lu, Shan, Zheng, Wei, Tu, Datao, Feng, Yanhui, Chen, Xueyuan. In situ confined growth of ultrasmall perovskite quantum dots in metal-organic frameworks and their quantum confinement effect. NANOSCALE[J]. 2020, 12(32): 17113-17120, http://dx.doi.org/10.1039/d0nr04741d.[14] Li, Xingjun, Lu, Shan, Tu, Datao, Zheng, Wei, Chen, Xueyuan. Luminescent lanthanide metal-organic framework nanoprobes: from fundamentals to bioapplications. NANOSCALEnull. 2020, 12(28): 15021-15035, http://dx.doi.org/10.1039/d0nr03373a.[15] Li, Xingjun, Zhou, Shanyong, Lu, Shan, Tu, Datao, Zheng, Wei, Liu, Yan, Li, Renfu, Chen, Xueyuan. Lanthanide Metal-Organic Framework Nanoprobes for the In Vitro Detection of Cardiac Disease Markers. ACS APPLIED MATERIALS & INTERFACES[J]. 2019, 11(47): 43989-43995, http://dx.doi.org/10.1021/acsami.9b17637.[16] Jianxi Ke, Shan Lu, Xiaoying Shang, Yan Liu, Hanhan Guo, Wenwu You, Xingjun Li, Jin Xu, Renfu Li, Zhuo Chen, Xueyuan Chen. A Strategy of NIR Dual‐Excitation Upconversion for Ratiometric Intracellular Detection. ADVANCED SCIENCE[J]. 2019, 6(22): n/a-n/a, https://doaj.org/article/5a21835e8fc44375bd0e6daa31466548.[17] Li, Xingjun, Jiang, Feilong, Chen, Lian, Wu, Mingyan, Lu, Shan, Pang, Jiandong, Zhou, Kang, Chen, Xueyuan, Hong, Maochun. Two microporous metal-organic frameworks constructed from trinuclear cobalt(II) and cadmium(II) cluster subunits. CRYSTENGCOMM[J]. 2016, 18(13): 2239-2243, https://www.webofscience.com/wos/woscc/full-record/WOS:000372662600002.[18] Lu, Shan, Tu, Datao, Li, Xingjun, Li, Renfu, Chen, Xueyuan. A facile "ship-in-a-bottle" approach to construct nanorattles based on upconverting lanthanide-doped fluorides. NANO RESEARCH[J]. 2016, 9(1): 187-197, http://dx.doi.org/10.1007/s12274-015-0979-4.[19] Lu, Shan, Tu, Datao, Hu, Ping, Xu, Jin, Li, Renfu, Wang, Meng, Chen, Zhuo, Huang, Mingdong, Chen, Xueyuan. Multifunctional Nano-Bioprobes Based on Rattle-Structured Upconverting Luminescent Nanoparticles. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2015, 54(27): 7915-7919, http://dx.doi.org/10.1002/anie.201501468.[20] Lu Shan, Tu Datao, Hu Ping, Xu Jin, Li Renfu, Wang Meng, Chen Zhuo, Huang Mingdong, Chen Xueyuan. Multifunctional Nano-Bioprobes Based on Rattle-Structured Upconverting Luminescent Nanoparticles.. ANGEWANDTE CHEMIE (INTERNATIONAL ED. IN ENGLISH). 2015, [21] Wang, Meng, Chen, Zhuo, Zheng, Wei, Zhu, Haomiao, Lu, Shan, Ma, En, Tu, Datao, Zhou, Shanyong, Huang, Mingdong, Chen, Xueyuan. Lanthanide-doped upconversion nanoparticles electrostatically coupled with photosensitizers for near-infrared-triggered photodynamic therapy. NANOSCALE[J]. 2014, 6(14): 8274-8282, https://www.webofscience.com/wos/woscc/full-record/WOS:000338638900073.[22] Lu, Shan, An, Zhe, He, Jing, Li, Bo. Hierarchically-structured immobilized enzyme displaying the multi-functions of bio-membranes. JOURNAL OF MATERIALS CHEMISTRY[J]. 2012, 22(9): 3882-3888, https://www.webofscience.com/wos/woscc/full-record/WOS:000300187000030.[23] Lu, Shan, An, Zhe, Li, Jinyan, He, Jing. pH-Triggered Adsorption-Desorption of Enzyme in Mesoporous Host to Act on Macrosubstrate. JOURNAL OF PHYSICAL CHEMISTRY B[J]. 2011, 115(46): 13695-13700, https://www.webofscience.com/wos/woscc/full-record/WOS:000297000800032.[24] An, Zhe, Lu, Shan, Zhao, Liwei, He, Jing. Layered-Metal-Hydroxide Nanosheet Arrays with Controlled Nanostructures to Assist Direct Electronic Communication at Biointerfaces. LANGMUIR[J]. 2011, 27(20): 12745-12750, https://www.webofscience.com/wos/woscc/full-record/WOS:000295665400062.[25] Lu, Shan, Song, Zhihong, He, Jing. Diffusion-Controlled Protein Adsorption in Mesoporous Silica. JOURNAL OF PHYSICAL CHEMISTRY B[J]. 2011, 115(24): 7744-7750, https://www.webofscience.com/wos/woscc/full-record/WOS:000291709500004.[26] An, Zhe, He, Jing, Lu, Shan, Yang, Lan. Electrostatic-Induced Interfacial Assembly of Enzymes with Nanosheets: Controlled Orientation and Optimized Activity. AICHE JOURNAL[J]. 2010, 56(10): 2677-2686, https://www.webofscience.com/wos/woscc/full-record/WOS:000282288400017.[27] Lu, Shan, He, Jing, Guo, Xin. Architecture and Performance of Mesoporous Silica-Lipase Hybrids via Non-Covalent Interfacial Adsorption. AICHE JOURNAL[J]. 2010, 56(2): 506-514, https://www.webofscience.com/wos/woscc/full-record/WOS:000274047100017.[28] Lu, Shan, He, Jing, Liu, Zhijun. Tuning interfacial non-covalent interactions through biomimetic functionalization of inorganic surface: The case of lysozyme and mesocellular silica foam hybrids. CHEMICAL ENGINEERING JOURNAL[J]. 2009, 146(3): 503-514, http://dx.doi.org/10.1016/j.cej.2008.10.032.