(1) Brain-gut axis in Alzheimer's disease

(2) Multi-omics joint analysis algorithm

2018-08--2021-08    City University of Hong Kong, PhD

2009-09--2010-09    University of Edinburgh, MSc

2005-09--2009-07    Guizhou University, BSc

   

2025-01 ~ Present, Associate Investigator, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences

2021-09 ~ 2025-01, Assistant Investigator, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences

2016-03 ~ 2018-08, Project Manager, Shenzhen WeHealthGene Co. Ltd.

2010-12 ~ 2016-03, Bioinformatics Engineer, BGI Genomics Co. Ltd.

   

^#First Author, ^*Corresponding author.

(1) Xikang Feng^#, Yinhu Li^#, Jieyi Zheng^#, Xuhua Chen^#, Shuo Yang, Yu Chen*, Shuai Cheng Li*. (2026) MicrobialScope: an integrated genomic resource with rich annotations across bacteria, archaea, fungi, and viruses. Nucleic Acids Research 54(D1):D842-D851.

(2) Yinhu Li^#, Xikang Feng^#, Xuhua Chen^#, Shuo Yang, Zicheng Zhao, Yu Chen*, Shuai Cheng Li*. (2025) PlasmidScope: a comprehensive plasmid database with rich annotations and online analytical tools. Nucleic Acids Research 53(D1): D179-D188.

(3) Yinhu Li^#, Guangze Pan^#, Shuai Wang^#, Zhengtu Li, Ru Yang, Yiqi Jiang, Yu Chen*, Shuai Cheng Li*, Bairong Shen*. (2025) Comprehensive human respiratory genome catalogue underlies the high resolution and precision of the respiratory microbiome. Briefings in Bioinformatics 26(1): bbae620.

(4) Yijing Chen^#, Yinhu Li^#, Yingying Fan, Shuai Chen, Li Chen, Yuewen Chen, Yu Chen*. (2024) Gut microbiota-driven metabolic alterations reveal gut–brain communication in Alzheimer’s disease model mice. Gut Microbes 16(1): 2302310.

(5) Yinhu Li^#, Yijing Chen^#, Yingying Fan, Yuewen Chen, Yu Chen*. (2023) Dynamic network modeling of gut microbiota during Alzheimer’s disease progression in mice. Gut Microbes 15(1): 2172672.

(6) Yuchen^# Zhang, Yinhu Li^#, Yuguang Yang, Yiqing Wang, Xiao Cao, Yu Jin, Yue Xu, Shuai Cheng Li*, Qin Zhou*. (2021) Periodontal and peri-implant microbiome dysbiosis is associated with alterations in the microbial community structure and local stability. Frontiers in Microbiology, 12: 785191.

(7) Yinhu Li^#, Yiqi Jiang^#, Zhengtu Li^#, Yonghan Yu^#, Jiaxing Chen, Wenlong Jia, Yen Kaow Ng, Feng Ye*, Shuai Cheng Li*, Bairong Shen*. (2023) Both simulation and sequencing data reveal coinfections with multiple SARS-CoV-2 variants in the COVID-19 pandemic. Computational and Structural Biotechnology Journal 20: 1389-1401.

(8) Zhengtu Li^#, Yinhu Li^#, Linghua Li^#, Xiaoneng Mo^#, Shaoqiang Li, Mingzhou Xie, Yangqing Zhan, Ye Lin, Zhun Li, Min Xie, Zhaoming Chen, Airu Zhu, Ruosu Ying, Le Yu, Jincun Zhao, Shuai Cheng Li, Weiping Cai, Feng Ye. (2022) Alteration of the respiratory microbiome in COVID-19 patients with different severities. Journal of Genetics and Genomics 49(3): 258-261.

(9) Yinhu Li^#, Li Shen^#, Congfu Huang^#, Xiaoyu Li, Junru Chen, Shuai Cheng Li*, Bairong Shen*. (2021) Altered nitric oxide induced by gut microbiota reveals the connection between central precocious puberty and obesity. Clinical and Translational Medicine 11(2): e299.

(10) Zhengtu Li^#, Yinhu Li^#, Ruilin Sun^#, Shaoqiang Li^#, Lingdan Chen^#, Yangqing Zhan#, Mingzhou Xie, Jiasheng Yang, Yanqun Wang, Airu Zhu, Guoping Gu, Le Yu, Shuaicheng Li, Tingting Liu, Zhaoming Chen, Wenhua Jian, Qian Jiang, Xiaofen Su, Weili Gu, Liyan Chen, Jing Cheng, Jincun Zhao, Wenju Lu, Jinping Zheng, Shiyue Li, Nanshan Zhong, Feng Ye*. (2021) Longitudinal virological changes and underlying pathogenesis in hospitalized COVID-19 patients in Guangzhou, China. Science China Life Sciences 64(12): 2129-2143.