鱼类性别演化、鱼类生殖调控、鱼类遗传育种

   

090801-水产养殖

鱼类遗传育种，鱼类性别决定，鱼类生殖调控，

2008-09--2014-06   中国科学院大学   理学博士
2003-09--2007-06   武汉大学   理学学士

   

2024-01~现在, 中国科学院水生生物研究所, 研究员
2017-12~2023-12,中国科学院水生生物研究所, 副研究员
2014-07~2017-12,中国科学院水生生物研究所, 助理研究员

2023-08-01-2027-08-31,中国动物学会比较内分泌学专业委员会委员,
2022-11-01-2027-11-30,中国水产学会青年工作委员会, 副主任委员

   

（1） 异育银鲫“中科3号”的培育及应用, 一等奖, 院级, 2015

[1] 梅洁, 何志鹏, 巩高瑞, 熊阳, 郭稳杰, 李熙银. 一种鲇形目鱼表型特征测量的装置及方法. CN: CN117346685A, 2024-01-05.
[2] 甘瑞海, 桂建芳, 周莉, 高泽霞, 李志, 王忠卫, 李熙银, 汪洋, 张晓娟, 佟金凤. 一种无肌间刺银鲫的创制方法. CN: CN115943930B, 2024-03-19.
[3] 佟金凤, 桂建芳, 汪洋, 周莉, 李熙银, 李志, 王忠卫, 张晓娟, 甘瑞海. 一种抗鲫疱疹病毒银鲫的创制方法. CN: CN116267799B, 2024-04-09.
[4] 甘瑞海, 桂建芳, 周莉, 高泽霞, 李志, 王忠卫, 李熙银, 汪洋, 张晓娟, 佟金凤. 一种无肌间刺银鲫的创制方法. CN: CN115943930A, 2023-04-11.
[5] 桂建芳, 鲁蒙, 周莉, 汪洋, 王忠卫, 李志, 张勤灿, 朱子域, 李熙银, 张晓娟. 一种高效创制不育合成新多倍体鲫鱼的方法. CN: CN115735858B, 2024-04-19.
[6] 桂建芳, 鲁蒙, 周莉, 王忠卫, 李志, 张勤灿, 汪洋, 李熙银, 张晓娟. 一种抗疱疹病毒雌核生殖银鲫新品系的创制方法. CN: CN115486411A, 2022-12-20.
[7] 鲁蒙, 桂建芳, 周莉, 李志, 王忠卫, 汪洋, 李熙银, 张晓娟. 一种高效创制银鲫新多倍体雌核生殖克隆系的方法. CN: CN115486412A, 2022-12-20.
[8] 鲁蒙, 桂建芳, 周莉, 李志, 王忠卫, 汪洋, 李熙银, 张晓娟. 一种高效创制银鲫新多倍体雌核生殖克隆系的方法. CN: CN115486412B, 2024-04-02.
[9] 桂建芳, 鲁蒙, 周莉, 王忠卫, 李志, 张勤灿, 汪洋, 李熙银, 张晓娟. 一种抗疱疹病毒雌核生殖银鲫新品系的创制方法. CN: CN115486411B, 2024-04-19.
[10] 李志, 李熙银, 汪洋, 王忠卫, 周莉, 王焘, 韩笑, 俞兆曦, 连总强, 桂建芳. 一种高效创制黄河鲶mstn基因突变体的方法. CN: CN112375757A, 2021-02-19.
[11] 李志, 桂建芳, 汪洋, 周莉, 王忠卫, 李熙银, 张晓娟, 鲁蒙, 余鹏. 一种高效创制异源八倍体银鲫的方法. CN: CN109874707A, 2019-06-14.

   

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[2] Aquaculture. 2024, 第 13 作者  通讯作者  
[3] 石倩, 丁苗, 汪洋, 周莉, 王忠卫, 张晓娟, 李志, 李熙银, 桂建芳. 双三倍体银鲫超数微小染色体的基因组特征. 水生生物学报[J]. 2023, 第 8 作者47(11): 1816-1826, http://ssswxb.ihb.ac.cn/article/doi/10.7541/2023.2023.0017.
[4] Wang Ming-Tao, Li Zhi, Ding Miao, Yao Tian-Zi, Yang Sheng, Zhang Xiao-Juan, Miao Chun, Du Wen-Xuan, Shi Qian, Li Shun, Mei Jie, Wang Yang, Wang Zhong-Wei, Zhou Li, Li Xi-Yin, Gui Jian-Fang. Two duplicated gsdf homeologs cooperatively regulate male differentiation by inhibiting cyp19a1a transcription in a hexaploid fish. PLoS Genetics[J]. 2022, 第 15 作者  通讯作者  18: e1010288, 
[5] Yang Wang, XiYin Li, WenJie Xu, Kun Wang, Bin Wu, Meng Xu, Yan Chen, LiJun Miao, ZhongWei Wang, Zhi Li, XiaoJuan Zhang, Zhan Yin, BoTong Zhou, YuLan Yang, ChengLong Zhu, MingLiang Hu, JiangMing Zheng, ChenGuang Feng, Qiang Qiu, LeTian Tian, Meng Lu, Fang Peng, WeiJia Lu, JinFeng Tong, JinGou Tong, BeiDe Fu, Peng Yu, Miao Ding, RuiHai Gan, QinQin Zhang, JianBo Jian, Chi Zhang, WeiMing He, Wei Yang, ZiCheng Zhao, QianQian Zhang, Qiang Gao, JunYang Xu, MingZhou Bai, YaPing Zhang, HuanMing Yang, XiaoDong Fang, Wen Wang, Li Zhou, JianFang Gui. Comparative genome anatomy reveals evolutionary insights into a unique amphitriploid fish. NATURE ECOLOGY & EVOLUTION[J]. 2022, 第 2 作者6(9): 1354-1366, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439954/.
[6] Lu, LongFeng, Jiang, JingYu, Du, WenXuan, Wang, XueLi, Li, ZhuoCong, Zhou, XiaoYu, Zhang, Can, Mou, ChengYan, Chen, DanDan, Li, Zhi, Zhou, Li, Gui, JianFang, Li, XiYin, Li, Shun. Fish female-biased gene cyp19a1a leads to female antiviral response attenuation between sexes by autophagic degradation of MITA. PLoS Pathogens[J]. 2022, 第 13 作者  通讯作者  18: e1010626, http://dx.doi.org/10.1371/journal.ppat.1010626.
[7] Li, Xi-Yin, mei jie, Ge Chu-Tian, Liu Xiao-Li. Sex determination mechanisms and sex control approaches in aquaculture animals. Science China Life Sciences[J]. 2022, 第 1 作者65(6): 1091-1122, 
[8] Wang, Tao, Li, Zhi, Yu, ZhaoXi, Wang, ZhongWei, Lian, ZongQiang, Du, WenXuan, Zhao, Xin, Wang, MingTao, Miao, Chun, Ding, Miao, Wang, Yang, Zhou, Li, Zhang, XiaoJuan, Li, XiYin, Gui, JianFang. Production of YY males through self-fertilization of an occasional hermaphrodite in Lanzhou catfish (Silurus lanzhouensis). AQUACULTURE[J]. 2021, 第 14 作者  通讯作者  539: http://dx.doi.org/10.1016/j.aquaculture.2021.736622.
[9] Zhao, Xin, Li, Zhi, Ding, Miao, Wang, Tao, Wang, MingTao, Miao, Chun, Du, WenXuan, Zhang, XiaoJuan, Wang, Yang, Wang, ZhongWei, Zhou, Li, Li, XiYin, Gui, JianFang. Genotypic Males Play an Important Role in the Creation of Genetic Diversity in Gynogenetic Gibel Carp. FRONTIERS IN GENETICS[J]. 2021, 第 12 作者  通讯作者  12: http://dx.doi.org/10.3389/fgene.2021.691923.
[10] Meng Lu, XiYin Li, Zhi Li, WenXuan Du, Li Zhou, Yang Wang, XiaoJuan Zhang, ZhongWei Wang, JianFang Gui. Regain of sex determination system and sexual reproduction ability in a synthetic octoploid male fish. SCIENCE CHINA Life Sciences[J]. 2021, 第 2 作者  通讯作者  64(1): 77-87, https://www.sciengine.com/doi/10.1007/s11427-020-1694-7.
[11] Ding, Miao, Li, XiYin, Zhu, ZhiXuan, Chen, JunHui, Lu, Meng, Shi, Qian, Wang, Yang, Li, Zhi, Zhao, Xin, Wang, Tao, Du, WenXuan, Miao, Chun, Yao, TianZi, Wang, MingTao, Zhang, XiaoJuan, Wang, ZhongWei, Zhou, Li, Gui, JianFang. Genomic anatomy of male-specific microchromosomes in a gynogenetic fish. PLOS GENETICS[J]. 2021, 第 2 作者  通讯作者  17(9): http://dx.doi.org/10.1371/journal.pgen.1009760.
[12] Chen, Fan, Li, XiYin, Zhou, Li, Yu, Peng, Wang, ZhongWei, Li, Zhi, Zhang, XiaoJuan, Wang, Yang, Gui, JianFang. Stable Genome Incorporation of Sperm-derived DNA Fragments in Gynogenetic Clone of Gibel Carp. MARINE BIOTECHNOLOGY[J]. 2020, 第 2 作者22(1): 54-66, http://dx.doi.org/10.1007/s10126-019-09930-w.
[13] Xi-Yin Li, Jian-Fang Gui. An epigenetic regulatory switch controlling temperature-dependent sex determination in vertebrates. 中国科学：生命科学英文版[J]. 2018, 第 1 作者61(8): 996-998, http://lib.cqvip.com/Qikan/Article/Detail?id=676033499.
[14] Li, XiYin, Liu, XiaoLi, Zhu, YaoJun, Zhang, Jun, Ding, Miao, Wang, MingTao, Wang, ZhongWei, Li, Zhi, Zhang, XiaoJuan, Zhou, Li, Gui, JianFang. Origin and transition of sex determination mechanisms in a gynogenetic hexaploid fish. HEREDITY[J]. 2018, 第 1 作者121(1): 64-74, https://www.webofscience.com/wos/woscc/full-record/WOS:000434984600006.
[15] Zhu, YaoJun, Li, XiYin, Zhang, Jun, Li, Zhi, Ding, Miao, Zhang, XiaoJuan, Zhou, Li, Gui, JianFang. Distinct sperm nucleus behaviors between genotypic and temperature-dependent sex determination males are associated with replication and expression-related pathways in a gynogenetic fish. BMC GENOMICS[J]. 2018, 第 2 作者19(1): http://dx.doi.org/10.1186/s12864-018-4823-6.
[16] Shao, GuangMing, Li, XiYin, Wang, Yang, Wang, ZhongWei, Li, Zhi, Zhang, XiaoJuan, Zhou, Li, Gui, JianFang. Whole Genome Incorporation and Epigenetic Stability in a Newly Synthetic Allopolyploid of Gynogenetic Gibel Carp. GENOME BIOLOGY AND EVOLUTION[J]. 2018, 第 2 作者10(9): 2394-2407, http://202.127.146.157/handle/2RYDP1HH/5834.
[17] XiYin Li, JianFang Gui. Diverse and variable sex determination mechanisms in vertebrates. SCIENCE CHINA Life Sciences[J]. 2018, 第 1 作者61(12): 1503-1514, https://www.sciengine.com/doi/10.1007/s11427-018-9415-7.
[18] XiYin Li, XiaoLi Liu, Miao Ding, Zhi Li, Li Zhou, XiaoJuan Zhang, JianFang Gui. A novel male-specific SET domain-containing gene setdm identified from extra microchromosomes of gibel carp males. Science Bulletin[J]. 2017, 第 1 作者62(8): 528-536, https://www.sciengine.com/doi/10.1016/j.scib.2017.04.002.
[19] Liu, XiaoLi, Li, XiYin, Jiang, FangFang, Wang, ZhongWei, Li, Zhi, Zhang, XiaoJuan, Zhou, Li, Gui, JianFang. Numerous mitochondrial DNA haplotypes reveal multiple independent polyploidy origins of hexaploids in Carassius species complex. ECOLOGY AND EVOLUTION[J]. 2017, 第 2 作者7(24): 10604-10615, http://dx.doi.org/10.1002/ece3.3462.
[20] Li, Xi-Yin, Zhang Qi-Ya, Zhang Jun, Zhou Li, Li Zhi, Zhang, Xiao-Juan, Wang Da, Gui Jian-Fang. Extra microchromosomes play male determination role in polyploidgibel carp. Genetics[J]. 2016, 第 1 作者203(3): 1415-1424, https://www.webofscience.com/wos/woscc/full-record/WOS:000379473600029.
[21] Pan, ZhengJun, Li, XiYin, Zhou, FengJian, Qiang, XiaoGang, Gui, JianFang. Identification of Sex-Specific Markers Reveals Male Heterogametic Sex Determination in Pseudobagrus ussuriensis. MARINE BIOTECHNOLOGY[J]. 2015, 第 2 作者17(4): 441-451, http://www.irgrid.ac.cn/handle/1471x/978701.
[22] Li Xi-Yin, Li Zhi, Zhang Xiao-Juan, Zhou Li, Gui Jian-Fang. Expression characterization of testicular DMRT1 in both Sertoli cells and spermatogenic cells of polyploidgibel carp. GENE[J]. 2014, 第 1 作者548(1): 119-125, http://dx.doi.org/10.1016/j.gene.2014.07.031.
[23] Li, XiYin, Zhang, XiaoJuan, Li, Zhi, Hong, Wei, Liu, Wei, Zhang, Jun, Gui, JianFang. Evolutionary history of two divergent Dmrt1 genes reveals two rounds of polyploidy origins in gibel carp. MOLECULAR PHYLOGENETICS AND EVOLUTION[J]. 2014, 第 1 作者78: 96-104, http://dx.doi.org/10.1016/j.ympev.2014.05.005.
[24] Da Wang, Huiling Mao, Jinxia Peng, Xiyin Li, Li Zhou, Jianfang Gui. Discovery of a male-biased mutant family and identification of a male-specific SCAR marker in gynogenetic gibel carp Carassius auratus gibelio. PROGRESS IN NATURAL SCIENCE[J]. 2009, 第 4 作者19(11): 1537-1544, http://lib.cqvip.com/Qikan/Article/Detail?id=32212638.

   

（ 1 ） 雌核生殖银鲫雄性发生及性别分化机制研究, 负责人, 国家任务, 2019-01--2022-12
（ 2 ） 青年人才托举工程, 负责人, 国家任务, 2015-11--2017-12
（ 3 ） 野生鱼类的品种设计与快速驯化, 参与, 中国科学院计划, 2019-11--2024-12
（ 4 ） 中国科学院青年创新促进会, 负责人, 中国科学院计划, 2020-01--2024-12
（ 5 ） 鲤鲫、草鱼优异种质资源鉴定, 参与, 国家任务, 2021-12--2026-11
（ 6 ） 淡水鱼类生长性状形成及调控网络研究, 参与, 国家任务, 2022-12--2027-11
（ 7 ） 水产动物重要病毒病的精准靶点防控技术原理, 负责人, 中国科学院计划, 2023-12--2028-11
（ 8 ） 多倍体养殖鱼类性别决定系统演化的遗传基础解析, 负责人, 国家任务, 2024-01--2027-12