李伟  男  研究员、博导  中国科学院动物研究所
电子邮件: liwei@ioz.ac.cn
通信地址: 北京市朝阳区大屯路甲3号院 中国科学院干细胞与再生医学创新研究院
邮政编码: 100101

研究领域

基因组信息及其表达调控是生命多样性和复杂性的重要基础,也是疾病治疗和健康干预的重要靶标和手段。我们特别感兴趣结合基因工程、细胞工程和合成生物学等手段建立新的基因工程技术和细胞/动物模型,用于(1)揭示生殖与再生相关性状及其种间进化差异的调控机制;(2)设计和制造功能定制化的细胞;(3)重大疾病的基因治疗。

招生信息

   
招生专业
1001J6-再生医学
招生方向
干细胞,基因工程

教育背景

2006-09--2013-01   中国科学院大学/中国科学院动物研究所   理学博士
2002-09--2006-06   武汉大学   学士
学历
研究生

学位
博士

工作经历

   
工作简历
2017-09~现在, 中国科学院动物研究所干细胞与生殖生物学国家重点实验室, 副主任
2016-01~现在, 中国科学院动物研究所, 研究员
2013-02~2015-12,中国科学院动物研究所, 星辰研究员
社会兼职
2020-01-01-今,发展中国家科学院(TWAS), 青年会士
2019-10-10-今,中国医药生物技术协会基因编辑技术分会, 常务委员
2019-10-01-今,中国动物学会生殖生物学分会, 副主任委员
2019-05-01-今,中国实验动物学会灵长类实验动物专业委员会, 常务委员
2018-05-01-今,中国细胞生物学学会衰老细胞生物学分会, 委员
2014-01-01-今,中国科学院青年创新促进会, 会员
2013-09-01-今,中国遗传学会青年委员会, 委员

教授课程

干细胞生物学
现代生殖医学之生理基础
胚胎工程
干细胞前沿技术
生殖生理学
干细胞研究进展系列讲座

专利与奖励

   
奖励信息
(1) 中国细胞生物学学会干细胞生物学分会干细胞研究创新奖, 其他, 2020
(2) 中国科学院杰出科技成就奖, , 院级, 2020
(3) 中国科学院青年科学家奖, , 院级, 2018
(4) 第十二届中国科学院杰出青年, , 院级, 2017
(5) 中源协和生命医学创新突破奖, , 其他, 2016
(6) 卢嘉锡青年人才奖, 院级, 2015
(7) 中国科学院杰出科技成就奖, , 院级, 2013
(8) 日本实验动物学会国际奖, , 其他, 2013

出版信息

   
发表论文
[1] Li, Guanglei, Li, Xiangyang, Zhuang, Songkuan, Wang, Liren, Zhu, Yifan, Chen, Yangcan, Sun, Wen, Wu, Zeguang, Zhou, Zhuo, Chen, Jia, Huang, Xingxu, Wang, Jin, Li, Dali, Li, Wei, Wang, Haoyi, Wei, Wensheng. Gene editing and its applications in biomedicine. SCIENCE CHINA-LIFE SCIENCESnull. 2022, 65(4): 660-700, http://dx.doi.org/10.1007/s11427-021-2057-0.
[2] Ren, Jilong, Yu, Dawei, Wang, Jing, Xu, Kai, Xu, Yanan, Sun, Renren, An, Peipei, Li, Chongyang, Feng, Guihai, Zhang, Ying, Dai, Xiangpeng, Zhao, Hongye, Wang, Zhengzhu, Han, Zhiqiang, Zhu, Haibo, Ding, Yuchun, You, Xiaoyan, Liu, Xueqin, Wu, Meng, Luo, Lin, Li, Ziyi, Yang, YongGuang, Hu, Zheng, Wei, HongJiang, Ge, Liangpeng, Hai, Tang, Li, Wei. Generation of immunodeficient pig with hereditary tyrosinemia type 1 and their preliminary application for humanized liver. CELL AND BIOSCIENCE[J]. 2022, 12(1): [3] Hu, Yanping, Li, Wei. Development and Application of CRISPR-Cas Based Tools. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGYnull. 2022, 10: http://dx.doi.org/10.3389/fcell.2022.834646.
[4] ZhengQuan He, XueWei Yuan, ZongBao Lu, YuHuan Li, YuFei Li, Xin Liu, Liu Wang, Ying Zhang, Qi Zhou, Wei Li. Pharmacological regulation of tissue fibrosis by targeting the mechanical contraction of myofibroblasts. Fundamental Research[J]. 2022, 2(1): 37-47, [5] Chen, Yangcan, Hu, Yanping, Wang, Xinge, Luo, Shengqiu, Yang, Ning, Chen, Yi, Li, Zhikun, Zhou, Qi, Li, Wei. Synergistic engineering of CRISPR-Cas nucleases enables robust mammalian genome editing. Innovation (Camb)[J]. 2022, 3(4): 100264-, [6] He, ZhengQuan, Li, YuHuan, Feng, GuHai, Yuan, XueWei, Lu, ZongBao, Dai, Min, Hu, YanPing, Zhang, Ying, Zhou, Qi, Li, Wei. Pharmacological Perturbation of Mechanical Contractility Enables Robust Transdifferentiation of Human Fibroblasts into Neurons. ADVANCED SCIENCE[J]. 2022, 9(13): http://dx.doi.org/10.1002/advs.202104682.
[7] Guanyi Jiao, Chenxin Wang, Yangcan Chen, Moyu Dai, Ying Zhang, Wei Li. Enhancing targeted transgene knock-in by donor recruitment. CELL PROLIFERATION[J]. 2021, 55(1): [8] Wang, Liying, Xu, Zhiliang, Wang, Libin, Liu, Chao, Wei, Huafang, Zhang, Ruidan, Chen, Yinghong, Wang, Lina, Liu, Wenwen, Xiao, Sai, Li, Wei, Li, Wei. Histone H2B ubiquitination mediated chromatin relaxation is essential for the induction of somatic cell reprogramming. CELL PROLIFERATION[J]. 2021, 54(8): http://dx.doi.org/10.1111/cpr.13080.
[9] Wang, Si, Cheng, Fang, Ji, Qianzhao, Song, Moshi, Wu, Zeming, Zhang, Yiyuan, Ji, Zhejun, Feng, Huyi, Belmonte, Juan Carlos Izpisua, Zhou, Qi, Qu, Jing, Li, Wei, Liu, GuangHui, Zhang, Weiqi. Hyperthermia differentially affects specific human stem cells and their differentiated derivatives. PROTEIN & CELL[J]. 2021, [10] Lu, Xukun, Zhang, Yu, Wang, Lijuan, Wang, Leyun, Wang, Huili, Xu, Qianhua, Xiang, Yunlong, Chen, Chaolei, Kong, Feng, Xia, Weikun, Lin, Zili, Ma, Sinan, Liu, Ling, Wang, Xiangguo, Ni, Hemin, Li, Wei, Guo, Yong, Xie, Wei. Evolutionary epigenomic analyses in mammalian early embryos reveal species-specific innovations and conserved principles of imprinting. SCIENCE ADVANCES[J]. 2021, 7(48): [11] Fu, Rui, Fang, Minghui, Xu, Kai, Ren, Jilong, Zou, Jun, Su, Long, Chen, Xinxin, An, PeiPei, Yu, Dawei, Ka, Meina, Hai, Tang, Li, Ziyi, Li, Wei, Yang, Yongguang, Zhou, Qi, Hu, Zheng. Generation ofGGTA1(-/-)beta 2M(-/-)CIITA(-/-)Pigs Using CRISPR/Cas9 Technology to Alleviate Xenogeneic Immune Reactions. TRANSPLANTATION[J]. 2020, 104(8): 1566-1573, http://dx.doi.org/10.1097/TP.0000000000003205.
[12] Wu, Jun, Hu, Zhongjie, Wang, Liu, Tan, Yuanqing, Hou, Wei, Li, Zhongwen, Gao, Tingting, Fan, Jiaqi, Guo, Baojie, Dai, Huaping, Li, Wei, Hao, Jie, Jin, Ronghua, Hu, Baoyang. First case of COVID-19 infused with hESC derived immunity- and matrix-regulatory cells. CELL PROLIFERATIONnull. 2020, 53(12): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645847/.
[13] Wang, LeYun, Li, ZhiKun, Wang, LiBin, Liu, Chao, Sun, XueHan, Feng, GuiHai, Wang, JiaQiang, Li, YuFei, Qiao, LianYong, Nie, Hu, Jiang, LiYuan, Sun, Hao, Xie, YaLi, Ma, SiNan, Wan, HaiFeng, Lu, FaLong, Li, Wei, Zhou, Qi. Overcoming Intrinsic H3K27me3 Imprinting Barriers Improves Post-implantation Development after Somatic Cell Nuclear Transfer. CELL STEM CELL[J]. 2020, 27(2): 315-+, http://dx.doi.org/10.1016/j.stem.2020.05.014.
[14] Li, Yufei, Li, Wei, Zhou, Qi. Haploid pluripotent stem cells: twofold benefits with half the effort in genetic screening and reproduction. CURRENT OPINION IN GENETICS & DEVELOPMENTnull. 2020, 64: 6-12, http://dx.doi.org/10.1016/j.gde.2020.05.013.
[15] Fu, Rui, Yu, Dawei, Ren, Jilong, Li, Chongyang, Wang, Jing, Feng, Guihai, Wang, Xuepeng, Wan, Haifeng, Li, Tianda, Wang, Libin, Zhang, Ying, Hai, Tang, Li, Wei, Zhou, Qi. Domesticated cynomolgus monkey embryonic stem cells allow the generation of neonatal interspecies chimeric pigs. PROTEIN & CELL[J]. 2020, 11(2): 97-107, http://lib.cqvip.com/Qikan/Article/Detail?id=7101576097.
[16] 李鹏承, 万海峰, 李伟. 非人灵长类胚胎工程研究进展. 生命科学[J]. 2020, 32(7): 661-663, http://lib.cqvip.com/Qikan/Article/Detail?id=7102923976.
[17] Chen, Baohui, Niu, Yuyu, Wang, Haoyi, Wang, Kejian, Yang, Hui, Li, Wei. Recent advances in CRISPR research. PROTEIN & CELL[J]. 2020, 11(11): 786-791, http://lib.cqvip.com/Qikan/Article/Detail?id=7103601388.
[18] Wu, Jun, Song, Dingyun, Li, Zhongwen, Guo, Baojie, Xiao, Yani, Liu, Wenjing, Liang, Lingmin, Feng, Chunjing, Gao, Tingting, Chen, Yanxia, Li, Ying, Wang, Zai, Wen, Jianyan, Yang, Shengnan, Liu, Peipei, Wang, Lei, Wang, Yukai, Peng, Liang, Stacey, Glyn Nigel, Hu, Zheng, Feng, Guihai, Li, Wei, Huo, Yan, Jin, Ronghua, ShyhChang, Ng, Zhou, Qi, Wang, Liu, Hu, Baoyang, Dai, Huaping, Hao, Jie. Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis. CELL RESEARCH[J]. 2020, 30(9): 794-809, http://lib.cqvip.com/Qikan/Article/Detail?id=7103057039.
[19] Ren, Jilong, Yu, Dawei, Fu, Rui, An, Peipei, Sun, Renren, Wang, Zhengzhu, Guo, Runfa, Li, Haoyun, Zhang, Ying, Li, Ziyi, Yang, YongGuang, Li, Wei, Hai, Tang, Hu, Zheng. IL2RG-deficient minipigs generated via CRISPR/Cas9 technology support the growth of human melanoma-derived tumours. CELL PROLIFERATION[J]. 2020, 53(10): https://www.webofscience.com/wos/woscc/full-record/WOS:000564461700001.
[20] Wu, Jun, Zhou, Xing, Tan, Yuanqing, Wang, Liu, Li, Tianda, Li, Zhongwen, Gao, Tingting, Fan, Jiaqi, Guo, Baojie, Li, Wei, Hao, Jie, Wang, Xianguang, Hu, Baoyang. Phase 1 trial for treatment of COVID-19 patients with pulmonary fibrosis using hESC-IMRCs. CELL PROLIFERATIONnull. 2020, 53(12): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645925/.
[21] Qu, Bin, Wu, Shijing, Jiao, Guanyi, Zou, Xuan, Li, Zhikun, Guo, Lu, Sun, Xuehan, Huang, Cheng, Sun, Zixi, Zhang, Ying, Li, Hui, Zhou, Qi, Sui, Ruifang, Li, Wei. Treating Bietti crystalline dystrophy in a high-fat diet-exacerbated murine model using gene therapy. GENE THERAPY[J]. 2020, 27(7-8): 370-382, http://dx.doi.org/10.1038/s41434-020-0159-3.
[22] 彭耀进, 李伟. 生命科技伦理问题与治理策略——以人-动物嵌合体研究为例. 科技导报[J]. 2020, 38(5): 42-49, http://lib.cqvip.com/Qikan/Article/Detail?id=7101521778.
[23] Mao, Junjie, Xu, Kai, Han, Jiabao, Feng, Guihai, Zhang, Ying, Li, Wei. Rapid construction of a whole-genome mutant library by combining haploid stem cells and inducible self-inactivating PiggyBac transposon. PROTEIN & CELL[J]. 2020, 11(6): 452-457, http://lib.cqvip.com/Qikan/Article/Detail?id=7102355335.
[24] Li, Jing, Wang, Chenxin, Feng, Guihai, Zhang, Linlin, Chen, Guilai, Sun, Hao, Wang, Jiaqiang, Zhang, Ying, Zhou, Qi, Li, Wei. Rbm14 maintains the integrity of genomic DNA during early mouse embryogenesis via mediating alternative splicing. CELL PROLIFERATION[J]. 2020, 53(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000500078600001.
[25] Weiqi Zhang, Shu Zhang, Pengze Yan, Jie Ren, Moshi Song, Jingyi Li, Jinghui Lei, Huize Pan, Si Wang, Xibo Ma, Shuai Ma, Hongyu Li, Fei Sun, Haifeng Wan, Wei Li, Piu Chan, Qi Zhou, GuangHui Liu, Fuchou Tang, Jing Qu. A single-cell transcriptomic landscape of primate arterial aging. NATURE COMMUNICATIONS[J]. 2020, 11(1): http://dx.doi.org/10.1038/s41467-020-15997-0.
[26] Tan, Yuanqing, Wang, Lei, Chen, Gang, Liu, Wenjing, Li, Zhongwen, Wang, Yukai, Wang, Liu, Li, Wei, Wu, Jun, Hao, Jie. Hyaluronate supports hESC-cardiomyocyte cell therapy for cardiac regeneration after acute myocardial infarction. CELL PROLIFERATION[J]. 2020, 53(12): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705924/.
[27] Wang, Lei, Wu, Wei, Gu, Qi, Liu, Zengping, Li, Qiyou, Li, Zhongwen, Fang, Jinhui, Liu, Wenjing, Wu, Jun, Zhang, Ying, Wang, Liu, Xu, Haiwei, Li, Wei, Hu, Baoyang, Zhou, Qi, Yin, Zhengqin, Hao, Jie. The effect of clinical-grade retinal pigment epithelium derived from human embryonic stem cells using different transplantation strategies. PROTEIN & CELLnull. 2019, 10(6): 455-460, http://lib.cqvip.com/Qikan/Article/Detail?id=7002265647.
[28] Hu, Zheng, Fu, Rui, Fang, Minghui, Zou, Jun, Xu, Kai, Hai, Tang, Li, Wei, Yang, YongGuang, Zhou, Qi. Generation of GGTA1-/-B2M-/CIITA-/- pigs using CRISPR/Cas9 technology to alleviate xenogeneic immune reactions. XENOTRANSPLANTATIONnull. 2019, 26(5): http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000488247000059.
[29] Li, Zhongwen, Wu, Jun, Wang, Lei, Han, Weifang, Yu, Juan, Liu, Xin, Wang, Yukai, Zhang, Ying, Feng, Guihai, Li, Wei, Stacey, Glyn Niger, Gu, Qi, Hu, Baoyang, Wang, Liu, Zhou, Qi, Hao, Jie. Generation of qualified clinical-grade functional hepatocytes from human embryonic stem cells in chemically defined conditions. CELL DEATH & DISEASE[J]. 2019, 10(10): http://dx.doi.org/10.1038/s41419-019-1967-5.
[30] Haifeng Gu, Xingxing Shi, Chao Liu, Chaoqun Wang, Ning Sui, Yu Zhao, Jiaqi Gong, Fuping Wang, Hong Zhang, Wei Li, Tongbiao Zhao. USP8 maintains embryonic stem cell stemness via deubiquitination of EPG5. Nature Communications[J]. 2019, 10(1): 1-9, https://doaj.org/article/c74f5c2d2f504fb9a202f4f7c7b79dfe.
[31] Li, Yufei, Wang, Leyun, Zhang, Linlin, He, Zhengquan, Feng, Guihai, Sun, Hao, Wang, Jiaqiang, Li, Zhikun, Liu, Chao, Han, Jiabao, Mao, Junjie, Li, Pengcheng, Yuan, Xuewei, Jiang, Liyuan, Zhang, Ying, Zhou, Qi, Li, Wei. Cyclin B3 is required for metaphase to anaphase transition in oocyte meiosis I. JOURNAL OF CELL BIOLOGY[J]. 2019, 218(5): 1553-1563, https://www.webofscience.com/wos/woscc/full-record/WOS:000466980400014.
[32] 任吉龙, 宋玉然, 李伟, 周琪, 海棠. 通过集成CRISPR/Cas9、受精卵注射和核移植技术快速高效制备胰腺缺陷小型猪模型. 内蒙古大学学报:自然科学版. 2019, 50(5): 513-517, http://lib.cqvip.com/Qikan/Article/Detail?id=7100059817.
[33] 王加强, 王乐韵, 冯桂海, 王昱凯, Yufei, Li, Xin, Li, Chao, Liu, Guanyi, Jiao, Cheng, Huang, Junchao, Shi, Tong, Zhou, Qi, Chen, Zhonghua, Liu, 李伟, 周琪. lincGET不对称表达影响小鼠2-细胞胚胎细胞命运选择. 科学新闻. 2019, 38-38, http://lib.cqvip.com/Qikan/Article/Detail?id=75888869504849574850484955.
[34] Teng, Fei, Li, Jing, Cui, Tongtong, Xu, Kai, Guo, Lu, Gao, Qingqin, Feng, Guihai, Chen, Chuanyuan, Han, Dali, Zhou, Qi, Li, Wei. Enhanced mammalian genome editing by new Cas12a orthologs with optimized crRNA scaffolds. GENOME BIOLOGY[J]. 2019, 20(1): https://doaj.org/article/ef19e2ad7d1c4c9788a858a91d36f8cb.
[35] Tongtong Cui, Zhikun Li, Qi Zhou, Wei Li. Current advances in haploid stem cells. Protein & Cell[J]. 2019, 11(1): 23-33, [36] Lei Wang, Wei Wu, Qi Gu, Zengping Liu, Qiyou Li, Zhongwen Li, Jinhui Fang, Wenjing Liu, Jun Wu, Ying Zhang, Liu Wang, Haiwei Xu, Wei Li, Baoyang Hu, Qi Zhou, Zhengqin Yin, Jie Hao. The effect of clinical-grade retinal pigment epithelium derived from human embryonic stem cells using different transplantation strategies. 蛋白质与细胞:英文版null. 2019, 10(6): 455-460, http://lib.cqvip.com/Qikan/Article/Detail?id=7002265647.
[37] Teng, Fei, Guo, Lu, Cui, Tongtong, Wang, XinGe, Xu, Kai, Gao, Qingqin, Zhou, Qi, Li, Wei. CDetection: CRISPR-Cas12b-based DNA detection with sub-attomolar sensitivity and single-base specificity. GENOME BIOLOGY[J]. 2019, 20(1): http://dx.doi.org/10.1186/s13059-019-1742-z.
[38] Wenliang Zhu, Boya Zhang, Mengqi Li, Fan Mo, Tingwei Mi, Yihui Wu, Zhaoqian Teng, Qi Zhou, Wei Li, Baoyang Hu. Precisely controlling endogenous protein dosage in hPSCs and derivatives to model FOXG1 syndrome. Nature Communications[J]. 2019, 10(1): 1-18, https://doaj.org/article/fe289d2c0c864031a37e09fb8593c020.
[39] Zhong, Xiuying, Cui, Peng, Cai, Yongping, Wang, Lihua, He, Xiaoping, Long, Peipei, Lu, Kangyang, Yan, Ronghui, Zhang, Ying, Pan, Xin, Zhao, Xiaoyang, Li, Wei, Zhang, Huafeng, Zhou, Qi, Gao, Ping. Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells. CELL METABOLISM[J]. 2019, 29(4): 979-+, http://dx.doi.org/10.1016/j.cmet.2018.11.007.
[40] Cui, Tongtong, Jiang, Liyuan, Li, Tianda, Teng, Fei, Feng, Guihai, Wang, Xuepeng, He, Zhengquan, Guo, Lu, Xu, Kai, Mao, Yihuan, Wang, Leyun, Yuan, Xuewei, Wang, Liu, Li, Wei, Zhou, Qi. Derivation of Mouse Haploid Trophoblast Stem Cells. CELL REPORTS[J]. 2019, 26(2): 407-+, http://dx.doi.org/10.1016/j.celrep.2018.12.067.
[41] Teng, Fei, Cui, Tongtong, Gao, Qingqin, Guo, Lu, Zhou, Qi, Li, Wei. Artificial sgRNAs engineered for genome editing with new Cas12b orthologs. CELL DISCOVERY[J]. 2019, 5(1): https://doaj.org/article/e8ef22cb7fda4f2b987b008ac5d4e070.
[42] Yufei Li, Leyun Wang, Linlin Zhang, Zhengquan He, Guihai Feng, Hao Sun, Jiaqiang Wang, Zhikun Li, Chao Liu, Jiabao Han, Junjie Mao, Pengcheng Li, Xuewei Yuan, Liyuan Jiang, Ying Zhang, Qi Zhou, Wei Li. Cyclin B3 is required for metaphase to anaphase transition in oocyte meiosis I. The Journal of Cell Biology[J]. 2019, 218(5): 1553-1563, [43] Yuan, Xuewei, He, Zhengquan, Mao, Junjie, Hu, Yanping, Liu, Xin, Guo, Jia, Liu, Zhonghua, Zhang, Ying, Li, Wei, Zhou, Qi. Reprogramming of fibroblasts to uterine glandular epithelium by a chemical cocktail induction. CELL DISCOVERY[J]. 2019, 5(1): http://dx.doi.org/10.1038/s41421-019-0096-8.
[44] 高情琴, 陈阳灿, 滕飞, 李伟. CRISPR基因编辑:更高效、更便捷、更普适. 前沿科学. 2019, 13(3): 8-13, http://lib.cqvip.com/Qikan/Article/Detail?id=7002989691.
[45] Teng, Fei, Li, Wei, Zhou, Qi. Synthetic chromosome evolves the yeast genome. SCIENCE CHINA-LIFE SCIENCESnull. 2019, 62(5): 708-709, http://lib.cqvip.com/Qikan/Article/Detail?id=74678871504849574853484951.
[46] Wang, Jiaqiang, Wang, Leyun, Feng, Guihai, Wang, Yukai, Li, Yufei, Li, Xin, Liu, Chao, Jiao, Guanyi, Huang, Cheng, Shi, Junchao, Zhou, Tong, Chen, Qi, Liu, Zhonghua, Li, Wei, Zhou, Qi. Asymmetric Expression of LincGET Biases Cell Fate in Two-Cell Mouse Embryos. CELL[J]. 2018, 175(7): 1887-+, http://dx.doi.org/10.1016/j.cell.2018.11.039.
[47] Wu, Jingyi, Xu, Jiawei, Liu, Bofeng, Yao, Guidong, Wang, Peizhe, Lin, Zili, Huang, Bo, Wang, Xuepeng, Li, Tong, Shi, Senlin, Zhang, Nan, Duan, Fuyu, Ming, Jia, Zhang, Xiangyang, Niu, Wenbin, Song, Wenyan, Jin, Haixia, Guo, Yihong, Dai, Shanjun, Hu, Linli, Fang, Lanlan, Wang, Qiujun, Li, Yuanyuan, Li, Wei, Na, Jie, Xie, Wei, Sun, Yingpu. Chromatin analysis in human early development reveals epigenetic transition during ZGA. NATURE[J]. 2018, 557(7704): 256-+, https://www.webofscience.com/wos/woscc/full-record/WOS:000431775100053.
[48] TiANDa Li, Leyun Wang, Xinxin Zhang, Liyuan Jiang, Yufei Li, Junjie Mao, Tongtong Cui, Wei Li, Liu Wang, Qi Zhou. Generation of rat-mouse chimeras by introducing single cells of rat inner cell masses into mouse blastocysts. 遗传学报:英文版. 2018, 45(6): 325-328, http://lib.cqvip.com/Qikan/Article/Detail?id=675742569.
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