基本信息
刘扩 男 杭州高等研究院
电子邮件： liukuo2015@sibcb.ac.cn
通信地址： 上海市徐汇区岳阳路320号细胞楼9楼
邮政编码：
电子邮件： liukuo2015@sibcb.ac.cn
通信地址： 上海市徐汇区岳阳路320号细胞楼9楼
邮政编码：
教育背景
2015-09--2020-07 中国科学院大学 博士研究生学历、博士学位
2011-09--2015-06 河北农业大学 本科学历、学士学位
2011-09--2015-06 河北农业大学 本科学历、学士学位
工作经历
工作简历
2022-08~2025-07,国科大杭州高等研究院, 副研究员
2020-07~2022-07,国科大杭州高等研究院, 博士后研究
2020-07~2022-07,国科大杭州高等研究院, 博士后研究
出版信息
发表论文
[1] 刘扩. Continuous genetic monitoring of transient mesenchymal gene activities in distal tubule and collecting duct epithelial cells during renal fibrosis. J Cell Biochem[J]. 2024, 第 1 作者
[2] 刘扩. Tracing the origin of alveolar stem cells in lung repair and regeneration. Cell[J]. 2024, 第 1 作者
[3] Pu, Wenjuan, Zhu, Huan, Zhang, Mingjun, Pikiolek, Monika, Ercan, Caner, Li, Jie, Huang, Xiuzhen, Han, Ximeng, Zhang, Zhenqian, Lv, Zan, Li, Yan, Liu, Kuo, He, Lingjuan, Liu, Xiuxiu, Heim, Markus H, Terracciano, Luigi M, Tchorz, Jan S, Zhou, Bin. Bipotent transitional liver progenitor cells contribute to liver regeneration. NATURE GENETICS[J]. 2023, 第 12 作者55(4):
[4] Xiuxiu Liu, Maoying Han, Wendong Weng, Yan Li, Wenjuan Pu, Kuo Liu, Xufeng Li, Lingjuan He, Ruilin Sun, Ruling Shen, Yulong He, Dandan Liang, Yi-Han Chen, Qing-Dong Wang, Jan S. Tchorz, Bin Zhou. Functional ProTracer identifies patterns of cell proliferation in tissues and underlying regulatory mechanisms. NPJ REGENERATIVE MEDICINE[J]. 2023, 第 6 作者8(1): 1-7, http://dx.doi.org/10.1038/s41536-023-00318-y.
[5] Liu, Kuo, Tang, Muxue, Xu, Wei, Meng, Xinfeng, Jin, Hengwei, Han, Maoying, Pu, Jing, Li, Yutang, Jiao, Fanke, Sun, Ruilin, Shen, Ruling, Lui, Kathy O, Lu, Lu, Zhou, Bin. An inducible hACE2 transgenic mouse model recapitulates SARS-CoV-2 infection and pathogenesis in vivo. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2023, 第 1 作者120(25): http://dx.doi.org/10.1073/pnas.2207210120.
[6] Liu, Kuo, Jin, Hengwei, Zhang, Shaohua, Tang, Muxue, Meng, Xinfeng, Li, Yan, Pu, Wenjuan, Lui, Kathy O, Zhou, Bin. Intercellular genetic tracing of cardiac endothelium in the developing heart. DEVELOPMENTAL CELL[J]. 2023, 第 1 作者 通讯作者 58(16): 1502-+, http://dx.doi.org/10.1016/j.devcel.2023.05.021.
[7] Developmental Cell. 2023, 第 1 作者
[8] Zhang, Shaohua, Zhao, Huan, Liu, Zixin, Liu, Kuo, Zhu, Huan, Pu, Wenjuan, He, Lingjuan, Wang, Rong A, Zhou, Bin. Monitoring of cell-cell communication and contact history in mammals. SCIENCE[J]. 2022, 第 4 作者378(6623): 965-+, http://dx.doi.org/10.1126/science.abo5503.
[9] Tang, Juan, Zhu, Huan, Tian, Xueying, Wang, Haixiao, Liu, Shaoyan, Liu, Kuo, Zhao, Huan, He, Lingjuan, Huang, Xiuzhen, Feng, Zhao, Ding, Zhangheng, Long, Ben, Yan, Yan, Smart, Nicola, Gong, Hui, Luo, Qingming, Zhou, Bin. Extension of Endocardium-Derived Vessels Generate Coronary Arteries in Neonates. CIRCULATION RESEARCH[J]. 2022, 第 6 作者130(3): 352-365,
[10] Zhang, Shaohua, Zhang, Qianyu, Liu, Zixin, Liu, Kuo, He, Lingjuan, Lui, Kathy O, Wang, Lixin, Zhou, Bin. Genetic dissection of intercellular interactions in vivo by membrane-permeable protein. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2022, 第 4 作者120(1): http://dx.doi.org/10.1073/pnas.2120582120.
[11] Jin, Hengwei, Liu, Kuo, Huang, Xiuzhen, Huo, Huanhuan, Mou, Jialing, Qiao, Zengyong, He, Ben, Zhou, Bin. Genetic Lineage Tracing of Pericardial Cavity Macrophages in the Injured Heart. CIRCULATION RESEARCH[J]. 2022, 第 2 作者130(11): 1682-1697, http://dx.doi.org/10.1161/CIRCRESAHA.122.320567.
[12] Liu, Kuo, Jin, Hengwei, Tang, Muxue, Zhang, Shaohua, Tian, Xueying, Zhang, Mingjun, Han, Ximeng, Liu, Xiuxiu, Tang, Juan, Pu, Wenjuan, Li, Yan, He, Lingjuan, Yang, Zhongzhou, Lui, Kathy O, Zhou, Bin. Lineage tracing clarifies the cellular origin of tissue-resident macrophages in the developing heart. JOURNAL OF CELL BIOLOGY[J]. 2022, 第 1 作者221(6):
[13] He, Lingjuan, Pu, Wenjuan, Liu, Xiuxiu, Zhang, Zhenqian, Han, Maoying, Li, Yi, Huang, Xiuzhen, Han, Ximeng, Li, Yan, Liu, Kuo, Shi, Mengyang, Lai, Liang, Sun, Ruilin, Wang, QingDong, Ji, Yong, Tchorz, Jan S, Zhou, Bin. Proliferation tracing reveals regional hepatocyte generation in liver homeostasis and repair. SCIENCE[J]. 2021, 第 10 作者371(6532):
[14] Liu, Xiuxiu, Pu, Wenjuan, He, Lingjuan, Li, Yan, Zhao, Huan, Li, Yi, Liu, Kuo, Huang, Xiuzhen, Weng, Wendong, Wang, QingDong, Shen, Linghong, Zhong, Tao, Sun, Kun, Ardehali, Reza, He, Ben, Zhou, Bin. Cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle. NATURE COMMUNICATIONS[J]. 2021, 第 7 作者12(1): http://dx.doi.org/10.1038/s41467-021-25933-5.
[15] Jin, Hengwei, Liu, Kuo, Zhou, Bin. Dual recombinases-based genetic lineage tracing for stem cell research with enhanced precision. SCIENCE CHINA-LIFE SCIENCES. 2021, 第 2 作者64(12): 2060-2072, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=7136861&detailType=1.
[16] Han, Ximeng, Zhang, Zhenqian, He, Lingjuan, Zhu, Huan, Li, Yan, Pu, Wenjuan, Han, Maoying, Zhao, Huan, Liu, Kuo, Li, Yi, Huang, Xiuzhen, Zhang, Mingjun, Jin, Hengwei, Lv, Zan, Tang, Juan, Wang, Jinjin, Sun, Ruilin, Fei, Jian, Tian, Xueying, Duan, Shengzhong, Wang, QingDong, Wang, Lixin, He, Ben, Zhou, Bin. A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting. CELL STEM CELL[J]. 2021, 第 9 作者28(6):
[17] Zhang, Shaohua, Li, Yan, Huang, Xiuzhen, Liu, Kuo, Wang, QingDong, Chen, Alex F, Sun, Kun, Lui, Kathy O, Zhou, Bin. Seamless Genetic Recording of Transiently Activated Mesenchymal Gene Expression in Endothelial Cells During Cardiac Fibrosis. CIRCULATION[J]. 2021, 第 4 作者144(25):
[18] Hengwei Jin, Kuo Liu, Juan Tang, Xiuzhen Huang, Haixiao Wang, Qianyu Zhang, Huan Zhu, Yan Li, Wenjuan Pu, Huan Zhao, Lingjuan He, Yi Li, Shaohua Zhang, Zhenqian Zhang, Yufei Zhao, Yanqing Qin, Stefan Pflanz, Karim E I Kasmi, Weiyi Zhang, Zhaoyuan Liu, Florent Ginhoux, Yong Ji, Ben He, Lixin Wang, Bin Zhou. Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury. NATURE COMMUNICATIONS[J]. 2021, 第 2 作者12(1): 1-15, https://doaj.org/article/1a384c9067664b0394d211c938d9df2a.
[19] Tang, Muxue, Liu, Kuo, Jin, Hengwei, Li, Yan, Zhang, Shaohua, Liu, Xiuxiu, Han, Ximeng, Han, Maoying, Zhang, Zhenqian, Zhou, Bin. Simultaneous quantitative assessment of two distinct cell lineages with a nuclear-localized dual genetic reporter. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY[J]. 2020, 第 2 作者146: 60-68, http://dx.doi.org/10.1016/j.yjmcc.2020.07.002.
[20] Tang, Juan, Wang, Haixiao, Huang, Xiuzhen, Li, Fei, Zhu, Huan, Li, Yan, He, Lingjuan, Zhang, Hui, Pu, Wenjuan, Liu, Kuo, Zhao, Huan, Bentzon, Jacob Fog, Yu, Ying, Ji, Yong, Nie, Yu, Tian, Xueying, Zhang, Li, Gao, Dong, Zhou, Bin. Arterial Sca1(+) Vascular Stem Cells Generate De Novo Smooth Muscle for Artery Repair and Regeneration. CELL STEM CELL[J]. 2020, 第 10 作者26(1): 81-+, http://dx.doi.org/10.1016/j.stem.2019.11.010.
[21] Xueying Tian, Lingjuan He, Kuo Liu, Wenjuan Pu, Huan Zhao, Yan Li, Xiuxiu Liu, Muxue Tang, Ruilin Sun, Jian Fei, Yong Ji, Zengyong Qiao, Kathy O Lui, Bin Zhou. Generation of a self‐cleaved inducible Cre recombinase for efficient temporal genetic manipulation. THE EMBO JOURNAL[J]. 2020, 第 3 作者39(4): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024834/.
[22] Liu, Kuo, Jin, Hengwei, Zhou, Bin. Genetic lineage tracing with multiple DNA recombinases: A user's guide for conducting more precise cell fate mapping studies. JOURNAL OF BIOLOGICAL CHEMISTRY. 2020, 第 1 作者295(19): 6413-6424, http://dx.doi.org/10.1074/jbc.REV120.011631.
[23] Liu, Kuo, Tang, Muxue, Liu, Qiaozhen, Han, Ximeng, Jin, Hengwei, Zhu, Huan, Li, Yan, He, Lingjuan, Ji, Hongbin, Zhou, Bin. Bi-directional differentiation of single bronchioalveolar stem cells during lung repair. CELL DISCOVERY. 2020, 第 1 作者6(1): http://dx.doi.org/10.1038/s41421-019-0132-8.
[24] Yu, Wei, Ma, Xueyan, Xu, Jinjin, Heumueller, Andreas Wilhelm, Fei, Zhaoliang, Feng, Xue, Wang, Xiaodong, Liu, Kuo, Li, Jinhui, Cui, Guizhong, Peng, Guangdun, Ji, Hongbin, Li, Jinsong, Jing, Naihe, Song, Hai, Lin, Zhiqiang, Zhao, Yun, Wang, Zuoyun, Zhou, Bin, Zhang, Lei. VGLL4 plays a critical role in heart valve development and homeostasis. PLOS GENETICS[J]. 2019, 第 8 作者15(2): https://doaj.org/article/7010330f90d545dcbf61dde5eb272596.
[25] Li, Yan, Lv, Zan, He, Lingjuan, Huang, Xiuzhen, Zhang, Shaohua, Zhao, Huan, Pu, Wenjuan, Li, Yi, Yu, Wei, Zhang, Libo, Liu, Xiuxiu, Liu, Kuo, Tang, Juan, Tian, Xueying, Wang, QingDong, Lui, Kathy O, Zhou, Bin. Genetic Tracing Identifies Early Segregation of the Cardiomyocyte and Nonmyocyte Lineages. CIRCULATION RESEARCH[J]. 2019, 第 12 作者125(3):
[26] Liu, Qiaozhen, Liu, Kuo, Cui, Guizhong, Huang, Xiuzhen, Yao, Shun, Guo, Wenke, Qin, Zhen, Li, Yan, Yang, Rui, Pu, Wenjuan, Zhang, Libo, He, Lingjuan, Zhao, Huan, Yu, Wei, Tang, Muxue, Tian, Xueying, Cai, Dongqing, Nie, Yu, Hu, Shengshou, Ren, Tao, Qiao, Zengyong, Huang, Hefeng, Zeng, Yi Arial, Jing, Naihe, Peng, Guangdun, Ji, Hongbin, Zhou, Bin. Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction (vol 51, pg 728, 2019). NATURE GENETICS. 2019, 第 2 作者51(4): 766-766,
[27] Kuo Liu, Muxue Tang, Hengwei Jin, Qiaozhen Liu, Lingjuan He, Huan Zhu, Xiuxiu Liu, Ximeng Han, Yan Li, Libo Zhang, Juan Tang, Wenjuan Pu, Zan Lv, Haixiao Wang, Hongbin Ji, Bin Zhou. Triple-cell lineage tracing by a dual reporter on a single allele. THE JOURNAL OF BIOLOGICAL CHEMISTRY. 2019, 第 1 作者295(3): 690-700, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970925/.
[28] Liu, Kuo, Yu, Wei, Tang, Muxue, Tang, Juan, Liu, Xiuxiu, Liu, Qiaozhen, Li, Yan, He, Lingjuan, Zhang, Libo, Evans, Sylvia M, Tian, Xueying, Lui, Kathy O, Zhou, Bin. A dual genetic tracing system identifies diverse and dynamic origins of cardiac valve mesenchyme. DEVELOPMENT[J]. 2018, 第 1 作者145(18): http://202.127.25.143/handle/331003/3367.
[29] Li, Yan, He, Lingjuan, Huang, Xiuzhen, Bhaloo, Shirin Issa, Zhao, Huan, Zhang, Shaohua, Pu, Wenjuan, Tian, Xueying, Li, Yi, Liu, Qiaozhen, Yu, Wei, Zhang, Libo, Liu, Xiuxiu, Liu, Kuo, Tang, Juan, Zhang, Hui, Cai, Dongqing, Ralf, Adams H, Xu, Qingbo, Lui, Kathy O, Zhou, Bin. Genetic Lineage Tracing of Nonmyocyte Population by Dual Recombinases. CIRCULATION[J]. 2018, 第 14 作者138(8):
[30] Zhang, Hui, Huang, Xiuzhen, Liu, Kuo, Tang, Juan, He, Lingjuan, Pu, Wenjuan, Liu, Qiaozhen, Li, Yan, Tian, Xueying, Wang, Yue, Zhang, Libo, Yu, Ying, Wang, Hongyan, Hu, Ronggui, Wang, Fengchao, Chen, Ting, Wang, QingDong, Qiao, Zengyong, Zhang, Li, Lui, Kathy O, Zhou, Bin. Fibroblasts in an endocardial fibroelastosis disease model mainly originate from mesenchymal derivatives of epicardium. CELL RESEARCH[J]. 2017, 第 3 作者27(9): 1157-1177,
[31] Pu, Wenjuan, Zhang, Hui, Huang, Xiuzhen, Tian, Xueying, He, Lingjuan, Wang, Yue, Zhang, Libo, Liu, Qiaozhen, Li, Yan, Li, Yi, Zhao, Huan, Liu, Kuo, Lu, Jie, Zhou, Yingqun, Huang, Pengyu, Nie, Yu, Yan, Yan, Hui, Lijian, Lui, Kathy O, Zhou, Bin. Mfsd2a(+) hepatocytes repopulate the liver during injury and regeneration. NATURE COMMUNICATIONS[J]. 2016, 第 12 作者7(1): https://doaj.org/article/8bcbb5f141f84e2ebd07ff6d5e9adba5.
[32] Zhang, Hui, Pu, Wenjuan, Tian, Xueying, Huang, Xiuzhen, He, Lingjuan, Liu, Qiaozhen, Li, Yan, Zhang, Libo, He, Liang, Liu, Kuo, Gillich, Astrid, Zhou, Bin. Genetic lineage tracing identifies endocardial origin of liver vasculature. NATURE GENETICS[J]. 2016, 第 10 作者48(5): 537-+, http://dx.doi.org/10.1038/ng.3536.
[2] 刘扩. Tracing the origin of alveolar stem cells in lung repair and regeneration. Cell[J]. 2024, 第 1 作者
[3] Pu, Wenjuan, Zhu, Huan, Zhang, Mingjun, Pikiolek, Monika, Ercan, Caner, Li, Jie, Huang, Xiuzhen, Han, Ximeng, Zhang, Zhenqian, Lv, Zan, Li, Yan, Liu, Kuo, He, Lingjuan, Liu, Xiuxiu, Heim, Markus H, Terracciano, Luigi M, Tchorz, Jan S, Zhou, Bin. Bipotent transitional liver progenitor cells contribute to liver regeneration. NATURE GENETICS[J]. 2023, 第 12 作者55(4):
[4] Xiuxiu Liu, Maoying Han, Wendong Weng, Yan Li, Wenjuan Pu, Kuo Liu, Xufeng Li, Lingjuan He, Ruilin Sun, Ruling Shen, Yulong He, Dandan Liang, Yi-Han Chen, Qing-Dong Wang, Jan S. Tchorz, Bin Zhou. Functional ProTracer identifies patterns of cell proliferation in tissues and underlying regulatory mechanisms. NPJ REGENERATIVE MEDICINE[J]. 2023, 第 6 作者8(1): 1-7, http://dx.doi.org/10.1038/s41536-023-00318-y.
[5] Liu, Kuo, Tang, Muxue, Xu, Wei, Meng, Xinfeng, Jin, Hengwei, Han, Maoying, Pu, Jing, Li, Yutang, Jiao, Fanke, Sun, Ruilin, Shen, Ruling, Lui, Kathy O, Lu, Lu, Zhou, Bin. An inducible hACE2 transgenic mouse model recapitulates SARS-CoV-2 infection and pathogenesis in vivo. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2023, 第 1 作者120(25): http://dx.doi.org/10.1073/pnas.2207210120.
[6] Liu, Kuo, Jin, Hengwei, Zhang, Shaohua, Tang, Muxue, Meng, Xinfeng, Li, Yan, Pu, Wenjuan, Lui, Kathy O, Zhou, Bin. Intercellular genetic tracing of cardiac endothelium in the developing heart. DEVELOPMENTAL CELL[J]. 2023, 第 1 作者 通讯作者 58(16): 1502-+, http://dx.doi.org/10.1016/j.devcel.2023.05.021.
[7] Developmental Cell. 2023, 第 1 作者
[8] Zhang, Shaohua, Zhao, Huan, Liu, Zixin, Liu, Kuo, Zhu, Huan, Pu, Wenjuan, He, Lingjuan, Wang, Rong A, Zhou, Bin. Monitoring of cell-cell communication and contact history in mammals. SCIENCE[J]. 2022, 第 4 作者378(6623): 965-+, http://dx.doi.org/10.1126/science.abo5503.
[9] Tang, Juan, Zhu, Huan, Tian, Xueying, Wang, Haixiao, Liu, Shaoyan, Liu, Kuo, Zhao, Huan, He, Lingjuan, Huang, Xiuzhen, Feng, Zhao, Ding, Zhangheng, Long, Ben, Yan, Yan, Smart, Nicola, Gong, Hui, Luo, Qingming, Zhou, Bin. Extension of Endocardium-Derived Vessels Generate Coronary Arteries in Neonates. CIRCULATION RESEARCH[J]. 2022, 第 6 作者130(3): 352-365,
[10] Zhang, Shaohua, Zhang, Qianyu, Liu, Zixin, Liu, Kuo, He, Lingjuan, Lui, Kathy O, Wang, Lixin, Zhou, Bin. Genetic dissection of intercellular interactions in vivo by membrane-permeable protein. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2022, 第 4 作者120(1): http://dx.doi.org/10.1073/pnas.2120582120.
[11] Jin, Hengwei, Liu, Kuo, Huang, Xiuzhen, Huo, Huanhuan, Mou, Jialing, Qiao, Zengyong, He, Ben, Zhou, Bin. Genetic Lineage Tracing of Pericardial Cavity Macrophages in the Injured Heart. CIRCULATION RESEARCH[J]. 2022, 第 2 作者130(11): 1682-1697, http://dx.doi.org/10.1161/CIRCRESAHA.122.320567.
[12] Liu, Kuo, Jin, Hengwei, Tang, Muxue, Zhang, Shaohua, Tian, Xueying, Zhang, Mingjun, Han, Ximeng, Liu, Xiuxiu, Tang, Juan, Pu, Wenjuan, Li, Yan, He, Lingjuan, Yang, Zhongzhou, Lui, Kathy O, Zhou, Bin. Lineage tracing clarifies the cellular origin of tissue-resident macrophages in the developing heart. JOURNAL OF CELL BIOLOGY[J]. 2022, 第 1 作者221(6):
[13] He, Lingjuan, Pu, Wenjuan, Liu, Xiuxiu, Zhang, Zhenqian, Han, Maoying, Li, Yi, Huang, Xiuzhen, Han, Ximeng, Li, Yan, Liu, Kuo, Shi, Mengyang, Lai, Liang, Sun, Ruilin, Wang, QingDong, Ji, Yong, Tchorz, Jan S, Zhou, Bin. Proliferation tracing reveals regional hepatocyte generation in liver homeostasis and repair. SCIENCE[J]. 2021, 第 10 作者371(6532):
[14] Liu, Xiuxiu, Pu, Wenjuan, He, Lingjuan, Li, Yan, Zhao, Huan, Li, Yi, Liu, Kuo, Huang, Xiuzhen, Weng, Wendong, Wang, QingDong, Shen, Linghong, Zhong, Tao, Sun, Kun, Ardehali, Reza, He, Ben, Zhou, Bin. Cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle. NATURE COMMUNICATIONS[J]. 2021, 第 7 作者12(1): http://dx.doi.org/10.1038/s41467-021-25933-5.
[15] Jin, Hengwei, Liu, Kuo, Zhou, Bin. Dual recombinases-based genetic lineage tracing for stem cell research with enhanced precision. SCIENCE CHINA-LIFE SCIENCES. 2021, 第 2 作者64(12): 2060-2072, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=7136861&detailType=1.
[16] Han, Ximeng, Zhang, Zhenqian, He, Lingjuan, Zhu, Huan, Li, Yan, Pu, Wenjuan, Han, Maoying, Zhao, Huan, Liu, Kuo, Li, Yi, Huang, Xiuzhen, Zhang, Mingjun, Jin, Hengwei, Lv, Zan, Tang, Juan, Wang, Jinjin, Sun, Ruilin, Fei, Jian, Tian, Xueying, Duan, Shengzhong, Wang, QingDong, Wang, Lixin, He, Ben, Zhou, Bin. A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting. CELL STEM CELL[J]. 2021, 第 9 作者28(6):
[17] Zhang, Shaohua, Li, Yan, Huang, Xiuzhen, Liu, Kuo, Wang, QingDong, Chen, Alex F, Sun, Kun, Lui, Kathy O, Zhou, Bin. Seamless Genetic Recording of Transiently Activated Mesenchymal Gene Expression in Endothelial Cells During Cardiac Fibrosis. CIRCULATION[J]. 2021, 第 4 作者144(25):
[18] Hengwei Jin, Kuo Liu, Juan Tang, Xiuzhen Huang, Haixiao Wang, Qianyu Zhang, Huan Zhu, Yan Li, Wenjuan Pu, Huan Zhao, Lingjuan He, Yi Li, Shaohua Zhang, Zhenqian Zhang, Yufei Zhao, Yanqing Qin, Stefan Pflanz, Karim E I Kasmi, Weiyi Zhang, Zhaoyuan Liu, Florent Ginhoux, Yong Ji, Ben He, Lixin Wang, Bin Zhou. Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury. NATURE COMMUNICATIONS[J]. 2021, 第 2 作者12(1): 1-15, https://doaj.org/article/1a384c9067664b0394d211c938d9df2a.
[19] Tang, Muxue, Liu, Kuo, Jin, Hengwei, Li, Yan, Zhang, Shaohua, Liu, Xiuxiu, Han, Ximeng, Han, Maoying, Zhang, Zhenqian, Zhou, Bin. Simultaneous quantitative assessment of two distinct cell lineages with a nuclear-localized dual genetic reporter. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY[J]. 2020, 第 2 作者146: 60-68, http://dx.doi.org/10.1016/j.yjmcc.2020.07.002.
[20] Tang, Juan, Wang, Haixiao, Huang, Xiuzhen, Li, Fei, Zhu, Huan, Li, Yan, He, Lingjuan, Zhang, Hui, Pu, Wenjuan, Liu, Kuo, Zhao, Huan, Bentzon, Jacob Fog, Yu, Ying, Ji, Yong, Nie, Yu, Tian, Xueying, Zhang, Li, Gao, Dong, Zhou, Bin. Arterial Sca1(+) Vascular Stem Cells Generate De Novo Smooth Muscle for Artery Repair and Regeneration. CELL STEM CELL[J]. 2020, 第 10 作者26(1): 81-+, http://dx.doi.org/10.1016/j.stem.2019.11.010.
[21] Xueying Tian, Lingjuan He, Kuo Liu, Wenjuan Pu, Huan Zhao, Yan Li, Xiuxiu Liu, Muxue Tang, Ruilin Sun, Jian Fei, Yong Ji, Zengyong Qiao, Kathy O Lui, Bin Zhou. Generation of a self‐cleaved inducible Cre recombinase for efficient temporal genetic manipulation. THE EMBO JOURNAL[J]. 2020, 第 3 作者39(4): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024834/.
[22] Liu, Kuo, Jin, Hengwei, Zhou, Bin. Genetic lineage tracing with multiple DNA recombinases: A user's guide for conducting more precise cell fate mapping studies. JOURNAL OF BIOLOGICAL CHEMISTRY. 2020, 第 1 作者295(19): 6413-6424, http://dx.doi.org/10.1074/jbc.REV120.011631.
[23] Liu, Kuo, Tang, Muxue, Liu, Qiaozhen, Han, Ximeng, Jin, Hengwei, Zhu, Huan, Li, Yan, He, Lingjuan, Ji, Hongbin, Zhou, Bin. Bi-directional differentiation of single bronchioalveolar stem cells during lung repair. CELL DISCOVERY. 2020, 第 1 作者6(1): http://dx.doi.org/10.1038/s41421-019-0132-8.
[24] Yu, Wei, Ma, Xueyan, Xu, Jinjin, Heumueller, Andreas Wilhelm, Fei, Zhaoliang, Feng, Xue, Wang, Xiaodong, Liu, Kuo, Li, Jinhui, Cui, Guizhong, Peng, Guangdun, Ji, Hongbin, Li, Jinsong, Jing, Naihe, Song, Hai, Lin, Zhiqiang, Zhao, Yun, Wang, Zuoyun, Zhou, Bin, Zhang, Lei. VGLL4 plays a critical role in heart valve development and homeostasis. PLOS GENETICS[J]. 2019, 第 8 作者15(2): https://doaj.org/article/7010330f90d545dcbf61dde5eb272596.
[25] Li, Yan, Lv, Zan, He, Lingjuan, Huang, Xiuzhen, Zhang, Shaohua, Zhao, Huan, Pu, Wenjuan, Li, Yi, Yu, Wei, Zhang, Libo, Liu, Xiuxiu, Liu, Kuo, Tang, Juan, Tian, Xueying, Wang, QingDong, Lui, Kathy O, Zhou, Bin. Genetic Tracing Identifies Early Segregation of the Cardiomyocyte and Nonmyocyte Lineages. CIRCULATION RESEARCH[J]. 2019, 第 12 作者125(3):
[26] Liu, Qiaozhen, Liu, Kuo, Cui, Guizhong, Huang, Xiuzhen, Yao, Shun, Guo, Wenke, Qin, Zhen, Li, Yan, Yang, Rui, Pu, Wenjuan, Zhang, Libo, He, Lingjuan, Zhao, Huan, Yu, Wei, Tang, Muxue, Tian, Xueying, Cai, Dongqing, Nie, Yu, Hu, Shengshou, Ren, Tao, Qiao, Zengyong, Huang, Hefeng, Zeng, Yi Arial, Jing, Naihe, Peng, Guangdun, Ji, Hongbin, Zhou, Bin. Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction (vol 51, pg 728, 2019). NATURE GENETICS. 2019, 第 2 作者51(4): 766-766,
[27] Kuo Liu, Muxue Tang, Hengwei Jin, Qiaozhen Liu, Lingjuan He, Huan Zhu, Xiuxiu Liu, Ximeng Han, Yan Li, Libo Zhang, Juan Tang, Wenjuan Pu, Zan Lv, Haixiao Wang, Hongbin Ji, Bin Zhou. Triple-cell lineage tracing by a dual reporter on a single allele. THE JOURNAL OF BIOLOGICAL CHEMISTRY. 2019, 第 1 作者295(3): 690-700, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970925/.
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科研活动
科研项目
（ 1 ） 肺脏再生修复中支气管与肺泡上皮之间的细胞命运转变 及分子机制研究, 负责人, 国家任务, 2024-01--2027-12
（ 2 ） 哺乳动物心脏心内膜的造血潜能及其机制调控研究, 负责人, 国家任务, 2022-01--2024-12
（ 3 ） 肺脏再生修复中支气管上皮与肺泡上皮之间的转分化及分子调控机制研究, 负责人, 研究所自主部署, 2022-08--2025-07
（ 4 ） 肺脏损伤再生中支气管上皮向肺泡上皮转分化的分子调控机制及靶向药物开发, 负责人, 研究所自主部署, 2022-11--2024-11
（ 2 ） 哺乳动物心脏心内膜的造血潜能及其机制调控研究, 负责人, 国家任务, 2022-01--2024-12
（ 3 ） 肺脏再生修复中支气管上皮与肺泡上皮之间的转分化及分子调控机制研究, 负责人, 研究所自主部署, 2022-08--2025-07
（ 4 ） 肺脏损伤再生中支气管上皮向肺泡上皮转分化的分子调控机制及靶向药物开发, 负责人, 研究所自主部署, 2022-11--2024-11
参与会议
（1）Tracing the origin of alveolar stem cells in lung repair and regeneration 组织器官再生修复的信息解码及有序调控重大研究计划第3届学术交流会 2024-03-29