有机氟化学/功能材料

   

070303-有机化学

有机氟化学
功能材料

1987-09--1992-12 中国科学院上海有机化学研究所 理学博士
1983-09--1987-07 复旦大学 理学学士

研究生

博士

   

2000-12~现在, 中国科学院上海有机化学研究所, 研究员、博导、课题组长
1996-10~2000-11,中国科学院上海有机化学研究所, 副研究员、课题组长
1994-03~1996-07,美国Clemson大学, 博士后
1993-03~1993-12,中国科学院上海有机化学研究所, 助理研究员

有机氟化学

   

   

[1] J. Fluorine Chem.. 2024, 第 4 作者  通讯作者  
[2] Tian-Cheng Zhong, Min Jiang, Jin-Tao Liu. Trifluoromethylsulfinylation Reaction of Activated Arenes and Indoles with Trifluoromethanesulfinyl Chloride. Eur. J. Org. Chem.[J]. 2024, 第 3 作者  通讯作者  e202301281, 
[3] Jia-Hui Li, Min Jiang, Jin-Tao Liu. The perfluoroalkylthiolation/decarbonylation reaction of 1,3-diketones with perfluoroalkanesulfenic acids. Org. Biomol. Chem.[J]. 2023, 第 3 作者  通讯作者  21: 9416-9421, 
[4] Li, JiaHui, Xu, JiaHong, Jiang, Min, Song, LiPing, Liu, JinTao. The Perfluoroalkylthiolation Reaction of Indoles and Activated Arenes with Perfluoroalkanesulfenic Acids. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY[J]. 2022, 第 5 作者  通讯作者  2022(43): 
[5] DongWei Sun, YongYan Zhou, Min Jiang, Tang Nian, JinTao Liu. CF3SOCl-promoted intramolecular cyclization of β-diketones: An efficient synthesis of flavones. TETRAHEDRON[J]. 2021, 第 5 作者  通讯作者  91: http://dx.doi.org/10.1016/j.tet.2021.132226.
[6] Xu, JiaHong, Jiang, Min, Song, LiPing, Liu, JinTao. A New Approach for the Synthesis of Perfluoroalkanesulfenic Acids. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY[J]. 2021, 第 4 作者  通讯作者  2021(12): 1919-1923, https://www.webofscience.com/wos/woscc/full-record/WOS:000632946900014.
[7] Qian Liu, XiaoBo Li, Min Jiang, ZhenJiang Liu, JinTao Liu. Synthesis of α-alkynyl perfluoroalkyl sulfoxides by the reaction of terminal alkynes and perfluoroalkanesulfinyl chlorides. TETRAHEDRON[J]. 2021, 第 5 作者  通讯作者  83: http://dx.doi.org/10.1016/j.tet.2021.131994.
[8] Zhao, Juan, Jiang, Min, Liu, JinTao. Transition metal-free aminofluorination of beta,gamma-unsaturated hydrazones: base-controlled regioselective synthesis of fluorinated dihydropyrazole and tetrahydropyridazine derivatives (vol 5, pg 1155, 2018). ORGANIC CHEMISTRY FRONTIERS. 2020, 第 3 作者  通讯作者  7(10): 1297-1297, https://www.webofscience.com/wos/woscc/full-record/WOS:000536816700013.
[9] Yan, Jun, Jiang, Min, Song, LiPing, Liu, JinTao. Oxytrifluoromethylthiolation of 2,3-Allenoates with Trifluoromethanesulfinyl Chloride: A Synthetic Approach to Trifluoromethylthiolated 4-Oxo-2(E)-alkenoates and Furans. ADVANCED SYNTHESIS & CATALYSIS[J]. 2020, 第 4 作者  通讯作者  362(14): 2882-2887, https://www.webofscience.com/wos/woscc/full-record/WOS:000541484500001.
[10] Li, Peng, Sun, DongWei, Jiang, Min, Liu, JinTao. Asymmetric aza-Henry reaction of fluoromethylated imines catalyzed by cinchona-derived bifunctional thiourea. TETRAHEDRON[J]. 2019, 第 4 作者  通讯作者  75(5): 603-607, http://dx.doi.org/10.1016/j.tet.2018.12.055.
[11] Li, Xiaobo, Zhao, Juan, Liu, Qian, Jiang, Min, Liu, Jintao. Addition of Perfluoroalkanesulfenic Acids to Alkynes and Allenes. CHINESE JOURNAL OF ORGANIC CHEMISTRY[J]. 2019, 第 5 作者  通讯作者  39(1): 183-191, http://dx.doi.org/10.6023/cjoc201808036.
[12] Yue, ShengLi, Jiang, Min, Li, Hui, Liu, JinTao. Triflylation of 1,4-Benzoquinones with sodium trifluoromethanesulfinate. JOURNAL OF FLUORINE CHEMISTRY[J]. 2019, 第 4 作者  通讯作者  228: http://dx.doi.org/10.1016/j.jfluchem.2019.109410.
[13] Sun, DongWei, Jiang, Min, Liu, JinTao. Novel Bifunctionalization of Activated Methylene: Base-Promoted Trifluoromethylthiolation of beta-Diketones with Trifluoromethanesulfinyl Chloride. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2019, 第 3 作者  通讯作者  25(46): 10797-10802, https://www.webofscience.com/wos/woscc/full-record/WOS:000481420300004.
[14] Sun, DongWei, Jiang, Xu, Jiang, Min, Lin, Yun, Liu, JinTao. POCl3-Promoted Trifluoromethylthiolation-Based Vicinal Bifunctionalization of Indoles with CF3SO2Na. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY[J]. 2018, 第 5 作者  通讯作者  2018(18): 2078-2081, https://www.webofscience.com/wos/woscc/full-record/WOS:000432225700005.
[15] Jin-Tao Liu. CuX2-mediated halocyclization of 1,1-difluoro-2,3-allenylphosphonic acid monoesters esynthesis of novel cyclic phosphate mimics. Tetrahedron. 2018, 第 1 作者  通讯作者  
[16] Zhao, Juan, Jiang, Min, Liu, JinTao. Transition metal-free aminofluorination of ss,gamma-unsaturated hydrazones: base-controlled regioselective synthesis of fluorinated dihydropyrazole and tetrahydropyridazine derivatives. ORGANIC CHEMISTRY FRONTIERS[J]. 2018, 第 3 作者  通讯作者  5(7): 1155-1159, https://www.webofscience.com/wos/woscc/full-record/WOS:000428670900014.
[17] Zhao, Juan, Jiang, Min, Liu, JinTao. Synthesis of Fluoromethyl-Substituted Isoxazolines via Transition Metal-Free Oxyfluorination of Alkenyl Oximes. ADVANCED SYNTHESIS & CATALYSIS[J]. 2017, 第 3 作者  通讯作者  359(10): 1626-1630, https://www.webofscience.com/wos/woscc/full-record/WOS:000401528100004.
[18] JunLi Li, XianJin Yang, Min Jiang, JinTao Liu. The preparation and cycloaddition reaction of 1-sulfonyl-1-trifluoromethyl allenes. TETRAHEDRON LETTERS[J]. 2017, 第 4 作者3377-3379, http://dx.doi.org/10.1016/j.tetlet.2017.07.050.
[19] Cao, ChunRu, Ou, Song, Jiang, Min, Liu, JinTao. An efficient method for the synthesis of gem-difluoroolefins. TETRAHEDRON LETTERS[J]. 2017, 第 4 作者  通讯作者  58(5): 482-485, http://dx.doi.org/10.1016/j.tetlet.2016.12.070.
[20] Xu, ZeFeng, Jiang, Min, Liu, JinTao. Preparation and Reactions of Perfluoroalkanesulfenyl Chlorides. CHINESE JOURNAL OF CHEMISTRY[J]. 2017, 第 3 作者  通讯作者  35(4): 442-446, http://lib.cqvip.com/Qikan/Article/Detail?id=672412960.
[21] Sun, DongWei, Jiang, Xu, Jiang, Min, Lin, Yun, Liu, JinTao. Selective Trifluoromethylthiolation and Trifluoromethylsulfinylation of Indoles with Sodium Trifluoromethanesulfinate Promoted by Phosphorus Reagents. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY[J]. 2017, 第 5 作者  通讯作者  2017(24): 3505-3511, https://www.webofscience.com/wos/woscc/full-record/WOS:000405126400017.
[22] Zhang Fan, Jiang Min, Liu JinTao. Base-controlled reaction of α,β-unsaturated trifluoromethyl ketone and dialkyl phosphite. TETRAHEDRON LETTERS[J]. 2017, 第 3 作者58(19): 1871-1874, http://dx.doi.org/10.1016/j.tetlet.2017.04.002.
[23] Li, XiaoBo, Zhao, Juan, Jiang, Min, Liu, JinTao. The addition of polyfluoroalkanesulfenic acids to alkenes. JOURNAL OF FLUORINE CHEMISTRY[J]. 2016, 第 4 作者  通讯作者  185: 24-30, http://dx.doi.org/10.1016/j.jfluchem.2016.03.002.
[24] Wang, Yanan, Jiang, Min, Liu, JinTao. Copper-Catalyzed Diastereoselective Synthesis of Trifluoromethylated Tetrahydrofurans. ADVANCED SYNTHESIS & CATALYSIS[J]. 2016, 第 3 作者  通讯作者  358(8): 1322-1327, https://www.webofscience.com/wos/woscc/full-record/WOS:000374556600015.
[25] Li, JunLi, Yang, XianJin, Wang, Yanan, Liu, JinTao. Synthesis of trifluoromethylated compounds from alcohols via alkoxydiphenylphosphines. JOURNAL OF FLUORINE CHEMISTRY[J]. 2015, 第 4 作者  通讯作者  178: 254-259, http://dx.doi.org/10.1016/j.jfluchem.2015.08.011.
[26] Wang, Yanan, Jiang, Min, Liu, JinTao. Copper-catalyzed stereoselective oxytrifluoro-methylation of propargyl amides for the construction of oxazolines. ORGANIC CHEMISTRY FRONTIERS[J]. 2015, 第 3 作者2(5): 542-547, https://www.webofscience.com/wos/woscc/full-record/WOS:000364445300016.
[27] Yang, Kai, Jiang, Min, Liu, JinTao. Synthesis of Chiral beta-Aminomalonates from 2-Chlorotetrafluoroethanesulfinyl Aldimines through the Mannich Reaction. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY[J]. 2015, 第 3 作者  通讯作者  2015(14): 3109-3115, https://www.webofscience.com/wos/woscc/full-record/WOS:000354212000018.
[28] Cao, ChunRu, Jiang, Min, Liu, JinTao. Metal-Mediated Reformatsky Reaction of Bromodifluoromethyl Ketone and Imine. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY[J]. 2015, 第 3 作者  通讯作者  2015(5): 1144-1151, https://www.webofscience.com/wos/woscc/full-record/WOS:000349391700028.
[29] Yang, Kai, Liu, JinTao. One-pot asymmetric reductive amination of ketones induced by polyfluoroalkanesulfinamide. JOURNAL OF FLUORINE CHEMISTRY[J]. 2015, 第 2 作者  通讯作者  173: 18-22, http://dx.doi.org/10.1016/j.jfluchem.2015.01.019.
[30] Wang, Yanan, Jiang, Min, Liu, JinTao. Copper-Catalyzed Intramolecular Carbotrifluoromethylation of Alkynes for the Construction of Trifluoromethylated Heterocycles. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2014, 第 3 作者  通讯作者  20(47): 15315-15319, https://www.webofscience.com/wos/woscc/full-record/WOS:000345234800006.
[31] Wang, Yanan, Jiang, Min, Liu, JinTao. Enantioselective Michael addition of cyclic ketones to nitroolefins catalyzed by a novel fluorine-insertion organocatalyst. TETRAHEDRON-ASYMMETRY[J]. 2014, 第 3 作者  通讯作者  25(3): 212-218, http://dx.doi.org/10.1016/j.tetasy.2013.12.015.
[32] Jin-Tao Liu. Asymmetric Pudovik reaction of chiral fluoroalkyl α,β-unsaturated ketimines and diphenyl phosphate. Chin. J. Chem.. 2014, 第 1 作者  通讯作者  
[33] Yan Zhao, XiaoJin Wang, Yun Lin, ChenXin Cai, JinTao Liu. Highly enantioselective direct Michael addition of 1,3-dicarbonyl compounds to β-fluoroalkyl-α-nitroalkenes. TETRAHEDRON. 2014, 第 5 作者2523-2528, http://dx.doi.org/10.1016/j.tet.2014.02.062.
[34] Yang Kai, Liu Lijuan, Liu Jintao. The Synthesis and Strecker Reaction of 2-Chlorotetrafluoroethanesulfinyl Ketimines. J. ORG. CHEM.[J]. 2014, 第 3 作者79(7): 3215-3220, http://ir.sioc.ac.cn/handle/331003/38837.
[35] Yan Zhao, XiaoJin Wang, ChenXin Cai, JinTao Liu. Organocatalytic aldol and domino Michael-aldol reactions of α,α-difluoro-β-keto esters with acetone. JOURNAL OF FLUORINE CHEMISTRY. 2014, 第 4 作者61-66, http://dx.doi.org/10.1016/j.jfluchem.2014.06.010.
[36] Liu, LiJuan, Liu, JinTao. 2-Chlorotetrafluoroethanesulfinamide induced asymmetric vinylogous Mannich reaction. TETRAHEDRON[J]. 2014, 第 2 作者  通讯作者  70(6): 1236-1245, http://dx.doi.org/10.1016/j.tet.2013.12.071.
[37] 王亚南, 蒋敏, 刘金涛. Copper-Catalyzed Regioselective Oxytrifluoromethylation of Allenes Using a CF3-Transfer Reagent. ADVSYNTHCATAL[J]. 2014, 第 3 作者356(14-15): 2907-2912, http://ir.sioc.ac.cn/handle/331003/38840.
[38] Jin-Tao Liu. Synthesis and identification of novel solution-stable sulfenic acids: perfluoroalkanesulfenic acids. Eur. J. Org. Chem.. 2014, 第 1 作者  通讯作者  
[39] Cao Chunru, Ou Song, Jiang Min, Liu Jintao. A practical route for the highly stereoselective synthesis of tetrasubstituted fluoroalkenes. ORG. BIOMOL. CHEM.[J]. 2014, 第 4 作者12(3): 467-473, http://ir.sioc.ac.cn/handle/331003/38832.
[40] 刘丽娟, 刘金涛. Zinc promoted asymmetric propargylation of N-(2-chlorotetrafluoroethanesulfin)imines. J. FLUOR. CHEM.[J]. 2014, 第 2 作者168: 44-49, http://ir.sioc.ac.cn/handle/331003/38843.
[41] Xu Zefeng, Cai Chenxin, Jiang Min, Liu Jintao. Copper-Catalyzed Regio- and Stereoselective O-Arylation of Enolates. ORG. LETT.[J]. 2014, 第 4 作者16(13): 3436-3439, http://ir.sioc.ac.cn/handle/331003/38838.
[42] 欧松, 曹春如, 蒋敏, 刘金涛. A Synthetic Approach to Tetrasubstituted Alkenes: Using beta-Carbonyl Benzothiazol-2-yl Sulfones as Electrophiles. EUR. J. ORG. CHEM.[J]. 2013, 第 4 作者2013(29): 6510-6513, http://www.irgrid.ac.cn/handle/1471x/869986.
[43] Xu Zefeng, Cai Chenxin, Liu Jintao. Copper-Catalyzed Regioselective Reaction of Internal Alkynes and Diaryliodonium Salts. ORG. LETT.[J]. 2013, 第 3 作者15(9): 2096-2099, http://www.irgrid.ac.cn/handle/1471x/848171.
[44] Ou, Song, Jiang, Min, Liu, JinTao. Synthesis of 2,2-difluoro-2H-chromenes through the tandem reaction of ethyl 3-bromo-3,3-difluoropropionate with salicylaldehyde derivatives. TETRAHEDRON[J]. 2013, 第 3 作者  通讯作者  69(51): 10820-10825, http://dx.doi.org/10.1016/j.tet.2013.10.091.
[45] Hui Yao, ChunRu Cao, Min Jiang, JinTao Liu. Metal-mediated Reformatsky reaction of bromodifluoromethyl ketone and aldehyde using water as solvent. JOURNAL OF FLUORINE CHEMISTRY[J]. 2013, 第 4 作者  通讯作者  45-50, http://dx.doi.org/10.1016/j.jfluchem.2013.08.012.
[46] Tao ZHANG, Ying ZHUO, XiaoPeng JIA, JinTao LIU, Hong GAO, FuHang SONG, Mei LIU, LiXin ZHANG. Cloning and characterization of the gene cluster required for beauvericin biosynthesis in Fusarium proliferatum. SCIENCE CHINA Life Sciences[J]. 2013, 第 4 作者56(7): 628-637, https://www.sciengine.com/doi/10.1007/s11427-013-4505-1.
[47] Zhen-Jiang Liu, Fan Zhang, Jin-Tao Liu. Regiospecific and diastereoselective aldol reaction of chiral N-sulfinyl metalloenamines with α,β-unsaturated trifluoromethyl ketones: Asymmetric synthesis of tertiary trifluoromethyl allylic carbinols. JOURNAL OF FLUORINE CHEMISTRY. 2012, 第 3 作者133: 102-107, http://dx.doi.org/10.1016/j.jfluchem.2011.09.002.
[48] Zhang, Tao, Jia, XiaoPeng, Zhuo, Ying, Liu, Mei, Gao, Hong, Liu, JinTao, Zhang, Lixin. Cloning and characterization of a novel 2-ketoisovalerate reductase from the beauvericin producer Fusarium proliferatum LF061. BMC BIOTECHNOLOGY[J]. 2012, 第 6 作者12(1): 55-55, http://dx.doi.org/10.1186/1472-6750-12-55.
[49] Jiang, XiuZhao, Cai, ChenXin, Liu, Tao, Uno, Hidemitsu. Novel syntheses and properties of meso-tetraaryl-octabromo-tetranaphtho2,3porphyrins (Ar(4)Br(8)TNPs). ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2012, 10(15): 3110-3115, https://www.webofscience.com/wos/woscc/full-record/WOS:000301958100028.
[50] Jin-Tao Liu. 8-Diazabicyclo[5.4.0]undec-7-ene (DBU) catalyzed regiospecific and diastereoselective reaction of chiral N-(tert-butanesulfinyl) ketimines and α,β-unsaturated trifluoromethyl ketones. Chin. J. Chem.. 2011, 第 1 作者  通讯作者  
[51] Jin-Tao Liu. 2-Chlorotetrafluoroethanesulfinamide induced diastereoselective three-component aminoallylation of aromatic aldehydes. 2011, 第 1 作者  通讯作者  
[52] 林云, 刘金涛. A facile method to construct cyclic alpha,alpha-difluoromethylenephosphonate-A novel cyclic phosphate mimic. J. FLUOR. CHEM.[J]. 2011, 第 2 作者132(5): 310-317, http://www.irgrid.ac.cn/handle/1471x/594171.
[53] 刘丽娟, 陈玲君, 李鹏, 李晓波, 刘金涛. Optically Pure Polyfluoroalkanesulfinamides: Synthesis and Application as Promising and Monitorable Chiral Auxiliaries. J. ORG. CHEM.[J]. 2011, 第 5 作者76(11): 4675-4681, http://www.irgrid.ac.cn/handle/1471x/594170.
[54] Li Peng, Liu Lijuan, Liu Jintao. Per(poly) fluoroalkanesulfinamides assisted diastereoselective three-component inverse-electron-demand aza Diels-Alder reaction. ORG. BIOMOL. CHEM.[J]. 2011, 第 3 作者9(1): 74-77, http://www.irgrid.ac.cn/handle/1471x/594169.
[55] 张帆, 刘振江, 刘金涛. Asymmetric aza-Henry reaction of chiral fluoroalkyl alpha,beta-unsaturated N-tert-butanesulfinyl ketoimines: an efficient approach to enantiopure fluoroalkylated alpha,beta-diamines and alpha,beta-diamino acids. ORG. BIOMOL. CHEM.[J]. 2011, 第 3 作者9(10): 3625-3628, http://www.irgrid.ac.cn/handle/1471x/594172.
[56] Jian Xu, Zhen-Jiang Liu, Xian-Jin Yang, Li-Min Wang, Guan-Long Chen, Jin-Tao Liu. One-pot asymmetric synthesis of α-trifluoromethylated amines from α-trifluoromethyl ketones. TETRAHEDRON. 2010, 第 6 作者66(46): 8933-8937, http://dx.doi.org/10.1016/j.tet.2010.09.047.
[57] Gao, Hong, Liu, Mei, Zhou, Xianlong, Liu, Jintao, Zhuo, Ying, Gou, Zhongxuan, Xu, Bing, Zhang, Wenquan, Liu, Xiangyang, Luo, Aiqun, Zheng, Chuansen, Chen, Xiaoping, Zhang, Lixin. Identification of avermectin-high-producing strains by high-throughput screening methods. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY[J]. 2010, 第 4 作者85(4): 1219-1225, http://www.irgrid.ac.cn/handle/1471x/768308.
[58] Li, Peng, Liu, ZhenJiang, Liu, JinTao. Iodocyclization of trifluoromethylallenic phosphonates: an efficient approach to trifluoromethylated oxaphospholenes. TETRAHEDRON[J]. 2010, 第 3 作者  通讯作者  66(51): 9729-9732, http://dx.doi.org/10.1016/j.tet.2010.10.040.
[59] Gao, Hong, Liu, Mei, Zhuo, Ying, Zhou, Xianlong, Liu, Jintao, Chen, Difei, Zhang, Wenquan, Gou, Zhongxuan, Shang, Peng, Zhang, Lixin. Assessing the Potential of an Induced-Mutation Strategy for Avermectin Overproducers. APPLIED AND ENVIRONMENTAL MICROBIOLOGY[J]. 2010, 第 5 作者76(13): 4583-4586, http://124.16.144.217/handle/311023/1501.
[60] Fan Zhang, Zhen-Jiang Liu, Jin-Tao Liu. Michael addition of N-sulfinyl metalloenamines to β-trifluoromethyl-α,β-unsaturated ester: an efficient access to chiral 4-trifluoromethyl-2-piperidones. TETRAHEDRON. 2010, 第 3 作者66(34): 6864-6868, http://dx.doi.org/10.1016/j.tet.2010.06.047.

   

（1） 氟烷基次磺酸及其衍生物的合成及性质研究，主持，国家级，2016-01--2019-12
（2） 手性含氟化合物的合成及其在不对称反应中的应用研究研究，主持，国家级，2012-01--2015-12

已指导学生

王小进  01  19132  

赵富录  01  19132  

林云  01  19132  

欧松  01  19132  

杨先金  01  19132  

李俊力  01  19132  

李晓波  01  19132  

陈玲君  02  19132  

梅英桥  01  19132  

刘振江  01  19132  

姚辉  02  19132  

赵燕  01  19132  

张帆  01  19132  

李鹏  01  19132  

耿晓宇  02  19132  

刘丽娟  01  19132  

姜秀召  01  19132  

曹春如  01  19132  

徐泽锋  01  19132  

杨凯  01  19132  

王亚南  01  19132  

现指导学生

赵娟  01  19132  

孙东伟  01  19132