071010-生物化学与分子生物学
071011-生物物理学

染色质组装与调控
结构生物学

2005-09--2010-06   中国科学院高能物理研究所   博士
2001-09--2005-06   湖南师范大学   学士

2022-01~现在, 中国科学院生物物理研究所, 研究员
2013-04~2021-12,中国科学院生物物理研究所, 副研究员
2010-07~2013-03,中国科学院生物物理研究所, 博士后

1. Chao-Pei Liu*, and Rui-Ming Xu*. Structure and function of histone chaperones in replication-coupled chromatin assembly. Current Opinion in Structural Biology, 2025, 92:103059.

2. Yan Ding, Jun Li, He-Li Jiang, Fang Suo, Guang-Can Shao, Xiao-Ran Zhang, Meng-Qiu Dong, Chao-Pei Liu, Rui-Ming Xu, Li-Lin Du. The ortholog of human DNAJC9 promotes histone H3-H4 degradation and is counteracted by Asf1 in fission yeast. Nucleic Acids Research, 2025, 53(3):gkaf036.

3. Chao-Pei Liu#*, Zhenyu Yu#, Jun Xiong#, Jie Hu#, Aoqun Song#, Dongbo Ding#, Cong Yu, Na Yang, Mingzhu Wang, Juan Yu, Peini Hou, Kangning Zeng, Zhenyu Li, Zhuqiang Zhang, Xinzheng Zhang, Wei Li, Zhiguo Zhang, Bing Zhu*, Guohong Li*, and Rui-Ming Xu*. Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 2023, 381(6660): eadd8673.

4. Weiran Ge#, Cong Yu#, Jingjing Li#, Zhenyu Yu, Xiaorong Li, Yan Zhang, Chao-Pei Liu, Yingfeng Li, Changlin Tian, Xinzheng Zhang, Guohong Li, Bing Zhu*, and Rui-Ming Xu*. Basis of the H2AK119 specificity of the Polycomb repressive deubiquitinase. Nature, 2023, 616(7955):176-182.

5. Ye Yue#, Wen-Si Yang#, Lin Zhang, Chao-Pei Liu, and Rui-Ming Xu. Topography of histone H3-H4 interaction with the Hat1-Hat2 acetyltransferase complex. Genes & Development, 2022, 36(7-8):408-413.

6. Hui Wang#, Boyuan Li#, Linyu Zuo, Bo Wang, Yan Yan, Kai Tian, Rong Zhou, Chenlu Wang, Xizi Chen, Yongpeng Jiang, Haonan Zheng, Fangfei Qin, Bin Zhang, Yang Yu, Chao-Pei Liu, Yanhui Xu, Juntao Gao, Zhi Qi, Wulan Deng, and Xiong Ji. The transcriptional coactivator RUVBL2 regulates Pol II clustering with diverse transcription factors. Nature Communications, 2022, 13(1):5703.

7. Jing Zhang#, Yan Zhang#, Qinglong You#, Chang Huang, Tiantian Zhang, Mingzhu Wang, Tianwei Zhang, Xiaocheng Yang, Jun Xiong, Yingfeng Li, Chao-Pei Liu, Zhuqiang Zhang, Rui-Ming Xu*, and Bing Zhu*. Highly enriched BEND3 prevents the premature activation of bivalent genes during differentiation. Science, 2022, 375(6584):1053-1058.

8. Chao-Pei Liu#*, Wenxing Jin#, Jie Hu, Mingzhu Wang, Jingjing Chen, Guohong Li, and Rui-Ming Xu*. Distinct histone H3-H4 binding modes of sNASP reveal the basis for cooperation and competition of histone chaperones. Genes & Development, 2021, 35(23-24):1610-1624.

9. Wenxing Jin#, Jia Wang#, Chao-Pei Liu, Hong-Wei Wang*, and Rui-Ming Xu*. Structural Basis for pri-miRNA Recognition by Drosha. Molecular Cell, 2020, 78(3):423-433.e5.

10. Peini Hou#, Chang Huang#, Chao-Pei Liu, Na Yang, Tianshu Yu, Yuxin Yin, Bing Zhu*, and Rui-Ming Xu*. Structural Insights into Stimulation of Ash1L's H3K36 Methyltransferase Activity through Mrg15 Binding. Structure, 2019, 27(5):837-845.e3.

11. Chaoyang Xiong#, Zengqi Wen#, Juan Yu, Jun Chen, Chao-Pei Liu, Xiaodong Zhang, Ping Chen, Rui-Ming Xu, and Guohong Li. UBN1/2 of HIRA complex is responsible for recognition and deposition of H3.3 at cis-regulatory elements of genes in mouse ES cells. BMC Biology, 2018, 16(1):110.

12. Wenxing Jin#, Yi Wang#, Chao-Pei Liu#, Na Yang, Mingliang Jin, Yao Cong, Mingzhu Wang* and Rui-Ming Xu*. Structural basis for snRNA recognition by the double WD40-repeat domain of Gemin5. Genes & Development, 2016, 30(21): 2391-2403.

13. Chao-Pei Liu#, Chaoyang Xiong#, Mingzhu Wang, Zhouliang Yu, Na Yang,Ping Chen, Zhiguo Zhang, Guohong Li* and Rui-Ming Xu*. Structure of the variant histone H3.3-H4 heterodimer in complexwith its chaperone DAXX. Nature Structural & Molecular Biology, 2012, 19(12): 1287-1292.