基本信息

李启业  男  硕导 
电子邮件: liqiye@genomics.cn
通信地址: 广东省深圳市大鹏新区大鹏街道金沙路国家基因库
邮政编码:518000

招生信息

   
招生专业
0710Z1-基因组学
0710J3-生物信息学
招生方向
基因组演化与物种适应性
动物重要性状的起源和演化
动物发育和表型可塑性的表观调控机制

教育背景

2013-12--2016-09   丹麦哥本哈根大学   博士
2010-09--2013-07   华南理工大学   硕士
2006-09--2010-07   华南理工大学   学士

工作经历

   
工作简历
2022-06~现在, 深圳华大生命科学研究院, 研究所常务所长
2016-09~2022-06,深圳华大生命科学研究院, 研究中心主任
社会兼职
2019-09-10-今,华南农业大学, 兼职教授
2018-07-26-今,西北大学, 兼职副教授

教授课程

动物基因组学
表观遗传学基本原理和分析技术

专利与奖励

   
奖励信息
(1) 深圳市自然科学奖, 一等奖, 市地级, 2018
(2) 深圳市海外高层次人才, 市地级, 2017
(3) 深圳市盐田区“梧桐人才”, 市地级, 2017
(4) 深圳市盐田区生物产业高层次人才, 市地级, 2013

出版信息

   
发表论文
[1] Zijun Xiong, Ding He, Xuanming Guang, Qiye Li, Michail Kotsyfakis. Novel tRNA Gene Rearrangements in the Mitochondrial Genomes of Poneroid Ants and Phylogenetic Implication of Paraponerinae (Hymenoptera: Formicidae). LIFE[J]. 2023, 13(10): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608118/.
[2] Pei Zhang, Yuanzhen Zhu, Qunfei Guo, Ji Li, Xiaoyu Zhan, Hao Yu, Nianxia Xie, Huishuang Tan, Nina Lundholm, Lydia GarciaCuetos, Michael D Martin, Meritxell Ant Subirats, YiHsien Su, Iaki RuizTrillo, Mark Q Martindale, JrKai Yu, M Thomas P Gilbert, Guojie Zhang, Qiye Li. On the origin and evolution of RNA editing in metazoans. CELL REPORTS. 2023, 42(2): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989829/.
[3] Qiye Li, Mingyue Wang, Pei Zhang, Yang Liu, Qunfei Guo, Yuanzhen Zhu, Tinggang Wen, Xueqin Dai, Xiafang Zhang, Manuel Nagel, Bjarke Hamberg Dethlefsen, Nianxia Xie, Jie Zhao, Wei Jiang, Lei Han, Liang Wu, Wenjiang Zhong, Zhifeng Wang, Xiaoyu Wei, Wei Dai, Longqi Liu, Xun Xu, Haorong Lu, Huanming Yang, Jian Wang, Jacobus J Boomsma, Chuanyu Liu, Guojie Zhang, Weiwei Liu. A single-cell transcriptomic atlas tracking the neural basis of division of labour in an ant superorganism. NATURE ECOLOGY & EVOLUTION. 2022, 6(8): 1191-1204, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349048/.
[4] Altenburger, Andreas, Cai, Huimin, Li, Qiye, Drumm, Kirstine, Kim, Miran, Zhu, Yuanzhen, GarciaCuetos, Lydia, Zhan, Xiaoyu, Hansen, Per Juel, John, Uwe, Li, Shuaicheng, Lundholm, Nina. Limits to the cellular control of sequestered cryptophyte prey in the marine ciliate Mesodinium rubrum. ISME JOURNAL[J]. 2021, 15(4): 1056-1072, http://dx.doi.org/10.1038/s41396-020-00830-9.
[5] Zhou, Yang, ShearwinWhyatt, Linda, Li, Jing, Song, Zhenzhen, Hayakawa, Takashi, Stevens, David, Fenelon, Jane C, Peel, Emma, Cheng, Yuanyuan, Pajpach, Filip, Bradley, Natasha, Suzuki, Hikoyu, Nikaido, Masato, Damas, Joana, Daish, Tasman, Perry, Tahlia, Zhu, Zexian, Geng, Yuncong, Rhie, Arang, Sims, Ying, Wood, Jonathan, Haase, Bettina, Mountcastle, Jacquelyn, Fedrigo, Olivier, Li, Qiye, Yang, Huanming, Wang, Jian, Johnston, Stephen D, Phillippy, Adam M, Howe, Kerstin, Jarvis, Erich D, Ryder, Oliver A, Kaessmann, Henrik, Donnelly, Peter, Korlach, Jonas, Lewin, Harris A, Graves, Jennifer, Belov, Katherine, Renfree, Marilyn B, Grutzner, Frank, Zhou, Qi, Zhang, Guojie. Platypus and echidna genomes reveal mammalian biology and evolution. NATURE[J]. 2021, 592(7856): 756-+, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081666/.
[6] Qiye Li, Qunfei Guo, Yang Zhou, Huishuang Tan, Terry Bertozzi, Yuanzhen Zhu, Ji Li, Stephen Donnellan, Guojie Zhang. A draft genome assembly of the eastern banjo frog Limnodynastes dumerilii dumerilii (Anura:Limnodynastidae). GIGABYTE (2020)[J]. 2020, 1: https://doaj.org/article/249dc7e263f441fb875a912be321af46.
[7] Li Qiye. On the origin and evolution of RNA editing in metazoans. bioRxiv. 2020, [8] Zhang Pei, Chen Jiesi, Li Qiye, Sheng Longxiang, Gao Yixing, Lu Bingzheng, Zhu Wenbo, Zhan Xiaoyu, Li Yuan, Yuan Zhibing, Xu Gang, Qiu Bitao, Yan Min, Guo Chunxue, Wang Youqiong, Huang Yijun, Zhang Jingxia, Liu Fuyu, Tang Zhongwei, Lin Suizhen, Cooper David N, Yang Huanming, Wang Jian, Gao Yuqi, Yin Wei, Zhang Guojie, Yan Guangmei. Neuroprotectants attenuate hypobaric hypoxia-induced brain injuries in cynomolgus monkeys. ZOOLOGICAL RESEARCH[J]. 2020, 41(1): 3-19, http://lib.cqvip.com/Qikan/Article/Detail?id=7100883453.
[9] Farre, Marta, Li, Qiye, Darolti, Iulia, Zhou, Yang, Damas, Joana, Proskuryakova, Anastasia A, Kulemzina, Anastasia I, Chemnick, Leona G, Kim, Jaebum, Ryder, Oliver A, Ma, Jian, Graphodatsky, Alexander S, Zhang, Guoije, Larkin, Denis M, Lewin, Harris A. An integrated chromosome-scale genome assembly of the Masai giraffe (Giraffa camelopardalis tippelskirchi). GIGASCIENCE. 2019, 8(8): https://www.webofscience.com/wos/woscc/full-record/WOS:000491875600005.
[10] Farre, Marta, Li, Qiye, Zhou, Yang, Damas, Joana, Chemnick, Leona G, Kim, Jaebum, Ryder, Oliver A, Ma, Jian, Zhang, Guojie, Larkin, Denis M, Lewin, Harris A. A near-chromosome-scale genome assembly of the gemsbok (Oryx gazella): an iconic antelope of the Kalahari desert. GIGASCIENCE. 2019, 8(2): https://www.webofscience.com/wos/woscc/full-record/WOS:000462551600007.
[11] Farre, Marta, Kim, Jaebum, Proskuryakova, Anastasia A, Zhang, Yang, Kulemzina, Anastasia, I, Li, Qiye, Zhou, Yang, Xiong, Yingqi, Johnson, Jennifer L, Perelman, Polina L, Johnson, Warren E, Warren, Wesley C, Kukekova, Anna, V, Zhang, Guojie, OBrien, Stephen J, Ryder, Oliver A, Graphodatsky, Alexander S, Ma, Jian, Lewin, Harris A, Larkin, Denis M. Evolution of gene regulation in ruminants differs between evolutionary breakpoint regions and homologous synteny blocks. GENOME RESEARCH[J]. 2019, 29(4): 576-589, [12] Cai, Huimin, Li, Qiye, Fang, Xiaodong, Li, Ji, Curtis, Nicholas E, Altenburger, Andreas, Shibata, Tomoko, Feng, Mingji, Maeda, Taro, Schwartz, Julie A, Shigenobu, Shuji, Lundholm, Nina, Nishiyama, Tomoaki, Yang, Huanming, Hasebe, Mitsuyasu, Li, Shuaicheng, Pierce, Sidney K, Wang, Jian. A draft genome assembly of the solar-powered sea slug Elysia chlorotica. SCIENTIFIC DATA. 2019, 6: http://dx.doi.org/10.1038/sdata.2019.22.
[13] Li Qiye. Gonad Transcriptome Analysis of High Temperature Induced Sex Reversal in Chinese Tongue Sole, Cynoglossus semilaevis. Frontiers in Genetics. 2019, [14] Chen, Lei, Qin, Qiang, Jiang, Yu, Wang, Kun, Lin, Zeshan, Li, Zhipeng, Bibi, Faysal, Yang, Yongzhi, Wang, Jinhuan, Nie, Wenhui, Su, Weiting, Liu, Guichun, Li, Qiye, Fu, Weiwei, Pan, Xiangyu, Liu, Chang, Yang, Jie, Zhang, Chenzhou, Yin, Yuan, Wang, Yu, Zhao, Yue, Zhang, Chen, Wang, Zhongkai, Qin, Yanli, Liu, Wei, Wang, Bao, Ren, Yandong, Zhang, Ru, Zeng, Yan, da Fonseca, Rute R, Wei, Bin, Li, Ran, Wan, Wenting, Zhao, Ruoping, Zhu, Wenbo, Wang, Yutao, Duan, Shengchang, Gao, Yun, Zhang, Yong E, Chen, Chunyan, Hvilsom, Christina, Epps, Clinton W, Chemnick, Leona G, Doug, Yang, Mirarab, Siavash, Siegismund, Hans Redlef, Ryder, Oliver A, Gilbert, M Thomas P, Lewin, Harris A, Zhang, Guojie, Heller, Rasmus, Wang, Wen. Large-scale ruminant genome sequencing provides insights into their evolution and distinct traits. SCIENCE[J]. 2019, 364(6446): 1152-+, http://dx.doi.org/10.1126/science.aav6202.
[15] Xiong, Heng, Liu, Dongbing, Li, Qiye, Lei, Mengyue, Xu, Liqin, Wu, Liang, Wang, Zongji, Ren, Shancheng, Li, Wangsheng, Xia, Min, Lu, Lihua, Lu, Haorong, Hou, Yong, Zhu, Shida, Liu, Xin, Sun, Yinghao, Wang, Jian, Yang, Huanming, Wu, Kui, Xu, Xun, Lee, Leo J. RED-ML: a novel, effective RNA editing detection method based on machine learning. GIGASCIENCE[J]. 2017, 6(5): 1-8, http://dx.doi.org/10.1093/gigascience/gix012.
[16] Gao, Jian, Li, Qiye, Wang, Zongji, Zhou, Yang, Martelli, Paolo, Li, Fang, Xiong, Zijun, Wang, Jian, Yang, Huanming, Zhang, Guojie. Sequencing, de novo assembling, and annotating the genome of the endangered Chinese crocodile lizard Shinisaurus crocodilurus. GIGASCIENCE. 2017, 6(7): 1-6, http://dx.doi.org/10.1093/gigascience/gix041.

科研活动


科研项目
( 1 ) 后生动物 RNA 编辑的起源和功能演化, 负责人, 国家任务, 2016-01--2018-12
( 2 ) 鸟类免疫系统和内源性病 毒及外源性病毒在分子序列水平的协同演化关系, 负责人, 地方任务, 2018-03--2020-09
( 3 ) 裸鼹鼠社会分工的分子机制研究, 负责人, 地方任务, 2013-01--2016-12
( 4 ) RNA 编辑在蚂蚁社会分工过程中的作用, 参与, 国家任务, 2013-01--2016-12
( 5 ) 动物基因组大数据, 负责人, 企业委托, 2018-01--2022-12
( 6 ) 蚂蚁大脑转录组项目, 负责人, 企业委托, 2016-01--2018-12
( 7 ) 南海深海及岛礁重要生物资源及其环境适应性研究, 参与, 地方任务, 2019-12--2022-12
参与会议
(1)利用单细胞转录组技术追踪蚂蚁社会分工的神经生物学基础   2021年青年昆虫学者高峰论坛   2021-11-27
(2)On the origin and evolution of RNA editing in metazoans   2021-05-25
(3)RNA编辑在动物界的起源和演化   2019年广东省昆虫学会年会暨“粤港澳大湾区昆虫科学与技术”研讨会   2019-12-14
(4)RNA 编辑—挑战遗传学中心法则的转录后调控机制   广东省遗传学会第十届会员代表大会暨学术研讨会   2018-07-21
(5)Caste-specific RNA editomes in the leaf-cutting ant Acromyrmex echinatior   2014-07-18
(6)RNA编辑——调控蚂蚁等级分化和劳动分工的新表观机制   首届中国昆虫基因组学及国际“5000种昆虫基因组(i5k)”计划”研讨会   2013-12-15