基本信息
张琳琳 女 博导 中国科学院海洋研究所
电子邮件： linlinzhang@qdio.ac.cn
通信地址： 山东省青岛市南海路7号中国科学院海洋研究所2号楼313室
邮政编码：
电子邮件： linlinzhang@qdio.ac.cn
通信地址： 山东省青岛市南海路7号中国科学院海洋研究所2号楼313室
邮政编码：
研究领域
海洋生物演化与环境适应
招生信息
招生专业
070703-海洋生物学
090801-水产养殖
090801-水产养殖
招生方向
繁殖、发育与调控技术
基因组学
养殖遗传学与育种生物技术
基因组学
养殖遗传学与育种生物技术
教育背景
2007-09--2012-07 中国科学院研究生院 博士
2003-09--2007-06 中国海洋大学 学士
2003-09--2007-06 中国海洋大学 学士
工作经历
2019-01~现在, 中国科学院海洋研究所, 责任研究员
2017-11~2018-12,University of Florida, 博士后
2014-02~2017-10,Cornell University, 博士后
2013-07~2014-01,The Howard Hughes Medical Institute, 博士后
2012-07~2013-06,中国科学院海洋研究所, 助理研究员
2017-11~2018-12,University of Florida, 博士后
2014-02~2017-10,Cornell University, 博士后
2013-07~2014-01,The Howard Hughes Medical Institute, 博士后
2012-07~2013-06,中国科学院海洋研究所, 助理研究员
专利与奖励
奖励信息
（1） 中国海洋湖沼学会张福绥贝类奖青年创新奖, 其他, 2019
（2） 美国国家科学院院刊Cozzarelli 奖, 其他, 2018
（3） 牡蛎基因组解析与潮间带适应的分子机制, 二等奖, 省级, 2017
（4） 山东省优秀博士学位论文, 省级, 2013
（5） 中国科学院院长优秀奖, 院级, 2012
（2） 美国国家科学院院刊Cozzarelli 奖, 其他, 2018
（3） 牡蛎基因组解析与潮间带适应的分子机制, 二等奖, 省级, 2017
（4） 山东省优秀博士学位论文, 省级, 2013
（5） 中国科学院院长优秀奖, 院级, 2012
出版信息
发表论文
[1] International Journal of Molecular Science. 2024, 通讯作者
[2] the CRISPR Journal. 2024, 通讯作者
[3] Scientific Data. 2024, 通讯作者
[4] Yongnan Li, Yu Xue, Zhangjie Peng, Linlin Zhang. Immune diversity in lophotrochozoans, with a focus on recognition and effector systems. COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL[J]. 2023, 第 4 作者 通讯作者 21: 2262-2275, http://dx.doi.org/10.1016/j.csbj.2023.03.031.
[5] Yao, Shanshan, Li, Li, Guan, Xudong, He, Yan, Jouaux, Aude, Xu, Fei, Guo, Ximing, Zhang, Guofan, Zhang, Linlin. Pooled resequencing of larvae and adults reveals genomic variations associated with Ostreid herpesvirus 1 resistance in the Pacific oyster Crassostrea gigas. FRONTIERS IN IMMUNOLOGY[J]. 2022, 第 9 作者 通讯作者 13: http://dx.doi.org/10.3389/fimmu.2022.928628.
[6] Wang, Shuting, Teng, Dequn, Li, Xueyan, Yang, Peiwen, Da, Wa, Zhang, Yiming, Zhang, Yubo, Liu, Guichun, Zhang, Xinshuang, Wan, Wenting, Dong, Zhiwei, Wang, Donghui, Huang, Shun, Jiang, Zhisheng, Wang, Qingyi, Lohman, David J, Wu, Yongjie, Zhang, Linlin, Jia, Fenghai, Westerman, Erica, Zhang, Li, Wang, Wen, Zhang, Wei. The evolution and diversification of oakleaf butterflies. CELL[J]. 2022, 第 18 作者185(17): 3138-+, http://dx.doi.org/10.1016/j.cell.2022.06.042.
[7] Zhu, Xiaofei, Mu, Kang, Wan, Yi, Zhang, Linlin. Evolutionary history of the NLR gene families across lophotrochozoans. GENE[J]. 2022, 第 11 作者843: http://dx.doi.org/10.1016/j.gene.2022.146807.
[8] Jiulin Chan, Wei Zhang, Yue Xu, Yu Xue, Linlin Zhang. Electroporation-Based CRISPR/Cas9 Mosaic Mutagenesis of β-Tubulin in the Cultured Oyster. FRONTIERS IN MARINE SCIENCE[J]. 2022, 第 5 作者9: https://doaj.org/article/08fa0f954d3b408087dbb04ed4fa0513.
[9] Li, Qian, Li, Yongnan, Wang, Yue, Wu, Xuwen, Zhang, Linlin. Taxonomy and regeneration of a newly recorded Polychaete Capitella teleta (Annelida, Capitellidae) in the coastal water of Shandong, China. JOURNAL OF OCEANOLOGY AND LIMNOLOGY[J]. 2021, 第 5 作者 通讯作者 http://dx.doi.org/10.1007/s00343-021-0378-5.
[10] Chan, Jiulin, Wang, Lu, Li, Li, Mu, Kang, Bushek, David, Xu, Yue, Guo, Ximing, Zhang, Guofan, Zhang, Linlin. Transcriptomic Response to Perkinsus marinus in Two Crassostrea Oysters Reveals Evolutionary Dynamics of Host-Parasite Interactions. FRONTIERS IN GENETICS[J]. 2021, 第 9 作者 通讯作者 12: http://dx.doi.org/10.3389/fgene.2021.795706.
[11] Xin He, Fucun Wu, Linlin Zhang, Li Li, Guofan Zhang. Comparative and evolutionary analyses reveal conservation and divergence of the notch pathway in lophotrochozoa. SCIENTIFIC REPORTS[J]. 2021, 第 3 作者 通讯作者 11(1):
[12] Zhang, Linlin, Steward, Rachel A, Wheat, Christopher W, Reed, Robert D. High-Quality Genome Assembly and Comprehensive Transcriptome of the Painted Lady Butterfly Vanessa cardui. GENOME BIOLOGY AND EVOLUTION[J]. 2021, 第 1 作者 通讯作者 13(7): http://dx.doi.org/10.1093/gbe/evab145.
[13] Reed, Robert D, Selegue, Jayne E, Zhang, Linlin, Brunetti, Craig R. Transcription factors underlying wing margin color patterns and pupal cuticle markings in butterflies. EVODEVO[J]. 2020, 第 3 作者11(1): http://dx.doi.org/10.1186/s13227-020-00155-w.
[14] Lewis, James J, Geltman, Rachel C, Pollak, Patrick C, Rondem, Kathleen E, Van Belleghem, Steven M, Hubisz, Melissa J, Munn, Paul R, Zhang, Linlin, Benson, Caleb, MazoVargas, Anyi, Danko, Charles G, Counterman, Brian A, Papa, Riccardo, Reed, Robert D. Parallel evolution of ancient, pleiotropic enhancers underlies butterfly wing pattern mimicry. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2019, 第 8 作者116(48): 24174-24183, https://www.webofscience.com/wos/woscc/full-record/WOS:000499101100048.
[15] Huang, Baoyu, Tang, Xueying, Zhang, Linlin, Li, Li, Wang, Wei, Liu, Mingkun, Zhang, Guofan. IKK epsilon-like plays an important role in the innate immune signaling of the Pacific oyster (Crassostrea gigas). FISH & SHELLFISH IMMUNOLOGY[J]. 2019, 第 3 作者93: 551-558, http://ir.qdio.ac.cn/handle/337002/163250.
[16] 张琳琳. Oyster Versatile IKKa/bs Are Involved in Toll-Like Receptor and RIG-I-Like Receptor Signaling for Innate Immune Response. Frontiers in Immunology. 2019, 第 1 作者
[17] Li, Li, Li, Ao, Song, Kai, Meng, Jie, Guo, Ximing, Li, Shiming, Li, Chunyan, De Wit, Pierre, Que, Huayong, Wu, Fucun, Wang, Wei, Qi, Haigang, Xu, Fei, Cong, Rihao, Huang, Baoyu, Li, Yingxiang, Wang, Ting, Tang, Xueying, Liu, Sheng, Li, Busu, Shi, Ruihui, Liu, Youli, Bu, Chen, Zhang, Chi, He, Weiming, Zhao, Shancen, Li, Hongjun, Zhang, Shoudu, Zhang, Linlin, Zhang, Guofan. Divergence and plasticity shape adaptive potential of the Pacific oyster. NATURE ECOLOGY & EVOLUTION[J]. 2018, 第 29 作者2(11): 1751-1760, http://ir.qibebt.ac.cn/handle/337004/11183.
[18] Baoyu Huang, Linlin Zhang, Yishuai Du, Fei Xu, Li Li, Guofan Zhang. Characterization of the Mollusc RIG-I/MAVS Pathway Reveals an Archaic Antiviral Signalling Framework in Invertebrates. SCIENTIFIC REPORTS[J]. 2017, 第 2 作者7(1): https://doaj.org/article/af75537375d24606867e7b29811ca0e7.
[19] Zhang, Linlin, Martin, Arnaud, Perry, Michael W, van der Burg, Karin R L, Matsuoka, Yuji, Monteiro, Antonia, Reed, Robert D. Genetic Basis of Melanin Pigmentation in Butterfly Wings. GENETICS[J]. 2017, 第 1 作者 通讯作者 205(4): 1537-1550, http://dx.doi.org/10.1534/genetics.116.196451.
[20] Zhang, Linlin, MazoVargas, Anyi, Reed, Robert D. Single master regulatory gene coordinates the evolution and development of butterfly color and iridescence. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2017, 第 1 作者114(40): 10707-10712, http://dx.doi.org/10.1073/pnas.1709058114.
[21] MazoVargas, Anyi, Concha, Carolina, Livraghi, Luca, Massardo, Darli, Wallbank, Richard W R, Zhang, Linlin, Papador, Joseph D, MartinezNajera, Daniel, Jiggins, Chris D, Kronforst, Marcus R, Breuker, Casper J, Reed, Robert D, Patel, Nipam H, McMillan, W Owen, Martin, Arnaud. Macroevolutionary shifts of WntA function potentiate butterfly wing-pattern diversity. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2017, 第 6 作者114(40): 10701-10706, http://dx.doi.org/10.1073/pnas.1708149114.
[22] Li, Yingxiang, Zhang, Linlin, Qu, Tao, Tang, Xueying, Li, Li, Zhang, Guofan. Conservation and divergence of mitochondrial apoptosis pathway in the Pacific oyster, Crassostrea gigas. CELL DEATH & DISEASE[J]. 2017, 第 2 作者8: http://ir.qdio.ac.cn/handle/337002/143094.
[23] Tang, Xueying, Huang, Baoyu, Zhang, Linlin, Li, Li, Zhang, Guofan. Molecular characterization of Pacific oyster (Crassostrea gigas) IRAK4 gene and its role in MyD88-dependent pathway. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY[J]. 2017, 第 3 作者72: 21-29, http://ir.qdio.ac.cn/handle/337002/137057.
[24] Xueying Tang, Baoyu Huang, Linlin Zhang, Li Li, Guofan Zhang. TANK-binding kinase-1 broadly affects oyster immune response to bacteria and viruses. FISH AND SHELLFISH IMMUNOLOGY. 2016, 第 3 作者56: 330-335, http://www.corc.org.cn/handle/1471x/2376239.
[25] Huang, Baoyu, Zhang, Linlin, Du, Yishuai, Li, Li, Tang, Xueying, Zhang, Guofan. Molecular characterization and functional analysis of tumor necrosis factor receptor-associated factor 2 in the Pacific oyster. FISH & SHELLFISH IMMUNOLOGY[J]. 2016, 第 2 作者48: 12-19, http://dx.doi.org/10.1016/j.fsi.2015.11.027.
[26] Zhu, Qihui, Zhang, Linlin, Li, Li, Que, Huayong, Zhang, Guofan. Expression Characterization of Stress Genes Under High and Low Temperature Stresses in the Pacific Oyster, Crassostrea gigas. MARINE BIOTECHNOLOGY[J]. 2016, 第 2 作者18(2): 176-188, http://dx.doi.org/10.1007/s10126-015-9678-0.
[27] 张琳琳. Characterization of oyster woltage-dependent anion channel 2 (VDAC2) suggests its involvement in apoptosis and host defense. PloS one. 2016, 第 1 作者
[28] Guofan Zhang, Li Li, Jie Meng, Haigang Qi, Tao Qu, Fei Xu, Linlin Zhang. Molecular Basis for Adaptation of Oysters to Stressful Marine Intertidal Environments. ANNUAL REVIEW OF ANIMAL BIOSCIENCES. 2016, 第 7 作者4:
[29] Huang, Baoyu, Zhang, Linlin, Tang, Xueying, Zhang, Guofan, Li, Li. Genome-Wide Analysis of Alternative Splicing Provides Insights into Stress Adaptation of the Pacific Oyster. MARINE BIOTECHNOLOGY[J]. 2016, 第 2 作者18(5): 598-609, https://www.webofscience.com/wos/woscc/full-record/WOS:000388831000007.
[30] Tang, Xueying, Huang, Baoyu, Zhang, Linlin, Li, Li, Zhang, Guofan. TANK-binding kinase-1 broadly affects oyster immune response to bacteria and viruses. FISH & SHELLFISH IMMUNOLOGY[J]. 2016, 第 3 作者56: 330-335, http://www.corc.org.cn/handle/1471x/2376239.
[31] Baoyu Huang, Linlin Zhang, Yishuai Du, Li Li, Xueying Tang, Guofan Zhang. Molecular characterization and functional analysis of tumor necrosis factor receptor-associated factor 2 in the Pacific oyster. FISH AND SHELLFISH IMMUNOLOGY. 2016, 第 2 作者48: 12-19, http://dx.doi.org/10.1016/j.fsi.2015.11.027.
[32] Linlin Zhang, Robert D Reed. Genome editing in butterflies reveals that spalt promotes and Distal-less represses eyespot colour patterns. NATURE COMMUNICATIONS[J]. 2016, 第 1 作者7(1): https://doaj.org/article/6f809259ef6d46ec843d009355707cbc.
[33] Li, Yingxiang, Zhang, Linlin, Qu, Tao, Li, Li, Zhang, Guofan. Characterization of Oyster Voltage-Dependent Anion Channel 2 (VDAC2) Suggests Its Involvement in Apoptosis and Host Defense. PLOS ONE[J]. 2016, 第 2 作者11(1): https://doaj.org/article/5b668d6bf413482a8e3924570ef7a018.
[34] Huang, Baoyu, Zhang, Linlin, Li, Li, Tang, Xueying, Zhang, Guofan. Highly diverse fibrinogen-related proteins in the Pacific oyster Crassostrea gigas. FISH & SHELLFISH IMMUNOLOGY[J]. 2015, 第 2 作者43(2): 485-490, http://dx.doi.org/10.1016/j.fsi.2015.01.021.
[35] Baoyu Huang, Linlin Zhang, Li Li, Xueying Tang, Guofan Zhang. Highly diverse fibrinogen-related proteins in the Pacific oyster Crassostrea gigas. FISH AND SHELLFISH IMMUNOLOGY. 2015, 第 2 作者43(2): 485-490, http://dx.doi.org/10.1016/j.fsi.2015.01.021.
[36] Zhang, Linlin, Li, Li, Guo, Ximing, Litman, Gary W, Dishaw, Larry J, Zhang, Guofan. Massive expansion and functional divergence of innate immune genes in a protostome. SCIENTIFIC REPORTS[J]. 2015, 第 1 作者5: http://dx.doi.org/10.1038/srep08693.
[37] Meng, Jie, Zhang, Linlin, Li, Li, Li, Chunyan, Wang, Ting, Zhang, Guofan. Transcription factor CgMTF-1 regulates CgZnT1 and CgMT expression in Pacific oyster (Crassostrea gigas) under zinc stress. AQUATIC TOXICOLOGY[J]. 2015, 第 2 作者165: 179-188, http://dx.doi.org/10.1016/j.aquatox.2015.05.023.
[38] Meng, Jie, Zhang, Linlin, Huang, Baoyu, Li, Li, Zhang, Guofan. Comparative analysis of oyster (Crassostrea gigas) immune responses under challenge by different Vibrio strains and conditions. MOLLUSCAN RESEARCH[J]. 2015, 第 2 作者35(1): 1-11, https://www.webofscience.com/wos/woscc/full-record/WOS:000349164900001.
[39] Qu, Tao, Zhang, Linlin, Wang, Wei, Huang, Baoyu, Li, Yingxiang, Zhu, Qihui, Li, Li, Zhang, Guofan. Characterization of an inhibitor of apoptosis protein in Crassostrea gigas clarifies its role in apoptosis and immune defense. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY[J]. 2015, 第 2 作者51(1): 74-78, http://dx.doi.org/10.1016/j.dci.2015.02.011.
[40] Ximing Guo, Yan He, Linlin Zhang, Christophe Lelong, Aude Jouaux. Immune and stress response in oysters with insights on adaptation. Fish & Shellfish immunology[J]. 2015, 第 3 作者
[41] Huang, Baoyu, Zhang, Linlin, Du, Yishuai, Li, Li, Qu, Tao, Meng, Jie, Zhang, Guofan. Alternative splicing and immune response of Crassostrea gigas tumor necrosis factor receptor-associated factor 3. MOLECULAR BIOLOGY REPORTS[J]. 2014, 第 2 作者41(10): 6481-6491, https://www.webofscience.com/wos/woscc/full-record/WOS:000342440000019.
[42] Qu, Tao, Huang, Baoyu, Zhang, Linlin, Li, Li, Xu, Fei, Huang, Wen, Li, Chunyan, Du, Yishuai, Zhang, Guofan. Identification and Functional Characterization of Two Executioner Caspases in Crassostrea gigas. PLOS ONE[J]. 2014, 第 3 作者9(2): http://dx.doi.org/10.1371/journal.pone.0089040.
[43] 李颖翔, 杜以帅, 张琳琳, 李莉, 张国范. 利用RNA干扰技术研究长牡蛎TLR2-2基因对MyD88-2基因表达的影响. 湖北农业科学[J]. 2014, 第 3 作者53(12): 2860-2863, http://lib.cqvip.com/Qikan/Article/Detail?id=661986318.
[44] Yishuai Du, Linlin Zhang, Fei Xu, Baoyu Huang, Guofan Zhang, Li Li. Validation of housekeeping genes as internal controls for studying gene expression during Pacific oyster ( Crassostrea gigas ) development by quantitative real-time PCR. FISH AND SHELLFISH IMMUNOLOGY. 2013, 第 2 作者939-945, http://dx.doi.org/10.1016/j.fsi.2012.12.007.
[45] 张琳琳. Fosmid library construction and microsatellite analysis of the Pacific oyster, Crassostrea gigas. Molluscan Research. 2013, 第 1 作者
[46] Meng, Jie, Zhu, Qihui, Zhang, Linlin, Li, Chunyan, Li, Li, She, Zhicai, Huang, Baoyu, Zhang, Guofan. Genome and Transcriptome Analyses Provide Insight into the Euryhaline Adaptation Mechanism of Crassostrea gigas. PLOS ONE[J]. 2013, 第 3 作者8(3): https://doaj.org/article/eaa2f8c729a841a2a79e0b822740651c.
[47] Du, Yishuai, Zhang, Linlin, Xu, Fei, Huang, Baoyu, Zhang, Guofan, Li, Li. Validation of housekeeping genes as internal controls for studying gene expression during Pacific oyster (Crassostrea gigas) development by quantitative real-time PCR. FISH & SHELLFISH IMMUNOLOGY[J]. 2013, 第 2 作者34(3): 939-945, http://dx.doi.org/10.1016/j.fsi.2012.12.007.
[48] Du, Yishuai, Zhang, Linlin, Huang, Baoyu, Guan, Xudong, Li, Li, Zhang, Guofan. Molecular Cloning, Characterization, and Expression of Two Myeloid Differentiation Factor 88 (Myd88) in Pacific Oyster, Crassostrea gigas. JOURNAL OF THE WORLD AQUACULTURE SOCIETY[J]. 2013, 第 2 作者44(6): 759-774, https://www.webofscience.com/wos/woscc/full-record/WOS:000327822400001.
[49] Zhang, Guofan, Fang, Xiaodong, Guo, Ximing, Li, Li, Luo, Ruibang, Xu, Fei, Yang, Pengcheng, Zhang, Linlin, Wang, Xiaotong, Qi, Haigang, Xiong, Zhiqiang, Que, Huayong, Xie, Yinlong, Holland, Peter W H, Paps, Jordi, Zhu, Yabing, Wu, Fucun, Chen, Yuanxin, Wang, Jiafeng, Peng, Chunfang, Meng, Jie, Yang, Lan, Liu, Jun, Wen, Bo, Zhang, Na, Huang, Zhiyong, Zhu, Qihui, Feng, Yue, Mount, Andrew, Hedgecock, Dennis, Xu, Zhe, Liu, Yunjie, DomazetLoso, Tomislav, Du, Yishuai, Sun, Xiaoqing, Zhang, Shoudu, Liu, Binghang, Cheng, Peizhou, Jiang, Xuanting, Li, Juan, Fan, Dingding, Wang, Wei, Fu, Wenjing, Wang, Tong, Wang, Bo, Zhang, Jibiao, Peng, Zhiyu, Li, Yingxiang, Li, Na, Wang, Jinpeng, Chen, Maoshan, He, Yan, Tan, Fengji, Song, Xiaorui, Zheng, Qiumei, Huang, Ronglian, Yang, Hailong, Du, Xuedi, Chen, Li, Yang, Mei, Gaffney, Patrick M, Wang, Shan, Luo, Longhai, She, Zhicai, Ming, Yao, Huang, Wen, Zhang, Shu, Huang, Baoyu, Zhang, Yong, Qu, Tao, Ni, Peixiang, Miao, Guoying, Wang, Junyi, Wang, Qiang, Steinberg, Christian E W, Wang, Haiyan, Li, Ning, Qian, Lumin, Zhang, Guojie, Li, Yingrui, Yang, Huanming, Liu, Xiao, Wang, Jian, Yin, Ye, Wang, Jun. The oyster genome reveals stress adaptation and complexity of shell formation. NATURE[J]. 2012, 第 8 作者490(7418): 49-54, https://www.webofscience.com/wos/woscc/full-record/WOS:000309446800030.
[50] Zhang LinLin, Li Li, Zhang GuoFan. Sequence variability of fibrinogen-related proteins (FREPs) in Crassostrea gigas. CHINESE SCIENCE BULLETIN[J]. 2012, 第 1 作者57(25): 3312-3319, http://lib.cqvip.com/Qikan/Article/Detail?id=42817605.
[51] 张国范. The first identification of molluscan Ecsit in the Pacific oyster, Crassostrea gigas, and its expression against bacterial challenge.. Aquaculture Research. 2011,
[52] 张琳琳, 李莉, 张国范. 长牡蛎（Crassostrea gigas）EST 串联重复序列的组成和分布. 海洋科学[J]. 2011, 第 1 作者35(4): 9-14, http://qdhys.ijournal.cn/hykx/ch/reader/view_abstract.aspx?file_no=20110402&flag=1.
[53] 袁泽轶, 张琳琳, 张国范. 基于皱纹盘鲍（Haliotis discus hannai）EST数据库的串联重复序列特征分析. 海洋通报[J]. 2010, 第 2 作者59-64, http://lib.cqvip.com/Qikan/Article/Detail?id=32828115.
[2] the CRISPR Journal. 2024, 通讯作者
[3] Scientific Data. 2024, 通讯作者
[4] Yongnan Li, Yu Xue, Zhangjie Peng, Linlin Zhang. Immune diversity in lophotrochozoans, with a focus on recognition and effector systems. COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL[J]. 2023, 第 4 作者 通讯作者 21: 2262-2275, http://dx.doi.org/10.1016/j.csbj.2023.03.031.
[5] Yao, Shanshan, Li, Li, Guan, Xudong, He, Yan, Jouaux, Aude, Xu, Fei, Guo, Ximing, Zhang, Guofan, Zhang, Linlin. Pooled resequencing of larvae and adults reveals genomic variations associated with Ostreid herpesvirus 1 resistance in the Pacific oyster Crassostrea gigas. FRONTIERS IN IMMUNOLOGY[J]. 2022, 第 9 作者 通讯作者 13: http://dx.doi.org/10.3389/fimmu.2022.928628.
[6] Wang, Shuting, Teng, Dequn, Li, Xueyan, Yang, Peiwen, Da, Wa, Zhang, Yiming, Zhang, Yubo, Liu, Guichun, Zhang, Xinshuang, Wan, Wenting, Dong, Zhiwei, Wang, Donghui, Huang, Shun, Jiang, Zhisheng, Wang, Qingyi, Lohman, David J, Wu, Yongjie, Zhang, Linlin, Jia, Fenghai, Westerman, Erica, Zhang, Li, Wang, Wen, Zhang, Wei. The evolution and diversification of oakleaf butterflies. CELL[J]. 2022, 第 18 作者185(17): 3138-+, http://dx.doi.org/10.1016/j.cell.2022.06.042.
[7] Zhu, Xiaofei, Mu, Kang, Wan, Yi, Zhang, Linlin. Evolutionary history of the NLR gene families across lophotrochozoans. GENE[J]. 2022, 第 11 作者843: http://dx.doi.org/10.1016/j.gene.2022.146807.
[8] Jiulin Chan, Wei Zhang, Yue Xu, Yu Xue, Linlin Zhang. Electroporation-Based CRISPR/Cas9 Mosaic Mutagenesis of β-Tubulin in the Cultured Oyster. FRONTIERS IN MARINE SCIENCE[J]. 2022, 第 5 作者9: https://doaj.org/article/08fa0f954d3b408087dbb04ed4fa0513.
[9] Li, Qian, Li, Yongnan, Wang, Yue, Wu, Xuwen, Zhang, Linlin. Taxonomy and regeneration of a newly recorded Polychaete Capitella teleta (Annelida, Capitellidae) in the coastal water of Shandong, China. JOURNAL OF OCEANOLOGY AND LIMNOLOGY[J]. 2021, 第 5 作者 通讯作者 http://dx.doi.org/10.1007/s00343-021-0378-5.
[10] Chan, Jiulin, Wang, Lu, Li, Li, Mu, Kang, Bushek, David, Xu, Yue, Guo, Ximing, Zhang, Guofan, Zhang, Linlin. Transcriptomic Response to Perkinsus marinus in Two Crassostrea Oysters Reveals Evolutionary Dynamics of Host-Parasite Interactions. FRONTIERS IN GENETICS[J]. 2021, 第 9 作者 通讯作者 12: http://dx.doi.org/10.3389/fgene.2021.795706.
[11] Xin He, Fucun Wu, Linlin Zhang, Li Li, Guofan Zhang. Comparative and evolutionary analyses reveal conservation and divergence of the notch pathway in lophotrochozoa. SCIENTIFIC REPORTS[J]. 2021, 第 3 作者 通讯作者 11(1):
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发表著作
（1） A practical guide to CRISPR/Cas9 genome editing in Lepidoptera. Diversity and Evolution of Butterfly Wing Patterns, Springer, 2017-08, 第 1 作者