李静宜 女 中国科学院动物研究所
电子邮件: lijingyi@ioz.ac.cn
通信地址: 北京市朝阳区大屯路甲3号院干细胞大楼
邮政编码:100101
研究领域
致力于衰老的功能基因组学研究,综合运用多组学技术解析衰老及相关疾病的发生发展机制,挖掘新型衰老干预靶标,其工作加深了对灵长类干细胞与器官衰老的认识。
教育背景
工作经历
工作简历
社会兼职
2022-01-01-今,中国老年学和老年医学学会抗衰老分会, 委员
荣誉奖励
北京市科技新星计划(2024),中国科学院“青年创新促进会”会员(2020),中国科协青年人才托举工程(2017)
代表论著
(1) Single-nucleus interrogation of primate small intestinal aging reveals NCoR1 decline as a conserved feature that is reversed by metformin, Nature Aging, 2026
(2) Vitamin C conveys geroprotection on primate ovaries, Cell Stem Cell, 2025
(3) 衰老机制与干预研究进展, Research status and prospect of aging mechanism and intervention, 科技导报, 2024
(4) Biomarkers of aging, SCIENCE CHINA-LIFE SCIENCES, 2023
(5) The landscape of aging, SCIENCE CHINA LIFE SCIENCE, 2022
(6) A single-cell transcriptomic atlas of primate pancreatic islet aging, National Science Review, 2021
(7) Single-Cell Transcriptomic Atlas of Primate Ovarian Aging, CELL, 2020
(8) Detection of Colorectal Cancer in Circulating Cell-Free DNA by Methylated CpG Tandem Amplification and Sequencing, CLINICAL CHEMISTRY, 2019
(9) Genetic Enhancement in Cultured Human Adult Stem Cells Conferred by a Single Nucleotide Recoding, CELL RESEARCH, 2017
(10) Genome-scale detection of hypermethylated CpG islands in circulating cell-free DNA of hepatocellular carcinoma patients, CELL RESEARCH, 2015
(11) A Werner Syndrome Stem Cell Model Unveils Heterochromatin Alterations as a Driver of Human Aging, SCIENCE, 2015