基本信息

孔亚卓  男    中国科学院心理研究所
电子邮件: kongyz@psych.ac.cn
通信地址: 北京市朝阳区林萃路16号中国科学院心理研究所
邮政编码: 100101

研究领域

多模态脑与脊髓磁共振成像技术与分析;

​疼痛认知科学 - 脑机制、社会疼痛、疼痛共情等;

长期慢性疼痛与神经退行性疾病;

招生信息

孔亚卓研究员,本科毕业于中国科学技术大学自动化系,获英国谢菲尔德大学心理学系和系统工程系联培博士学位,后在牛津大学脑成像中心从事磁共振成像研究多年。2017年回国建立研究组,目前是国内唯一致力于脊髓功能磁共振成像的研究团队,在复杂脑皮层下成像序列以及整合分析上国际知名。研究成果发表在包括Brain, PNAS,Journal of Neuroscience,NeuroImage,Cerebral Cortex,Human Brain Mapping等神经科学领域重要杂志上。

疼痛综合神经影像实验室(LINIP)主要以多模态脑脊磁共振成像技术为核心手段,通过研究触觉痛觉痒觉的感知、传导、认知、调节的脊髓-脑干-脑皮层神经环路来揭示复杂躯体感知觉的神经机制,同时探讨疼痛共情和社会性疼痛的神经机制,在此基础上探索疼痛慢性化的生理心理机制以及对病理性疼痛的预测评估、干预评估及神经调控等镇痛策略的开发。

招生专业
0402Z2-认知神经科学
招生方向
基于脑成像的疼痛研究

教育背景

2001-10--2005-11   University of Sheffield   博士
1996-09--2001-07   中国科学技术大学   学士
学历
博士

学位
博士


工作经历

   
工作简历
2009-01~2016-11,University of Oxford, Senior research fellow 研究员
2006-01~2008-12,University of Manchester, 博士后

专利与奖励

   
专利成果
[1] 孔亚卓, 魏朝行, 张明. 一种大脑与颈髓同步功能磁共振像的获取和数据处理方法. CN: CN114494502A, 2022-05-13.
[2] 孔亚卓, 魏朝行, 张明. 一种大脑与颈髓同步功能磁共振像的获取和数据处理方法. CN: CN114494502A, 2022-05-13.
[3] 孔亚卓, 魏朝行, 张明. 一种大脑与颈髓同步功能磁共振像的获取和数据处理方法. CN: CN114494502A, 2022-05-13.

出版信息

   
发表论文
[1] Ming Zhang, Xiaomin Lin, Yongkang Zhi, Yan Mu, Yazhuo Kong. The dual facilitatory and inhibitory effects of social pain on physical pain perception. ISCIENCE[J]. 2024, 27(2): http://dx.doi.org/10.1016/j.isci.2024.108951.
[2] Ming Zhang, Yuqi Zhang, Yue Zhu, Xiaomin Lin, Yongkang Zhi, Yupu Zhu, Chuan Shi, Yazhuo Kong. Stigmatized experience is associated with exacerbated pain perception in depressed patients. BEHAVIOUR RESEARCH AND THERAPY[J]. 2023, 161: http://dx.doi.org/10.1016/j.brat.2023.104252.
[3] Wu, Xiao, Lu, Xuejing, Zhang, Huijuan, Wang, Xiao, Kong, Yazhuo, Hu, Li. The association between ballroom dance training and empathic concern: Behavioral and brain evidence. HUMAN BRAIN MAPPING[J]. 2023, 44(2): 315-326, http://dx.doi.org/10.1002/hbm.26042.
[4] Wu, Xiao, Lu, Xuejing, Zhang, Huijuan, Bi, Yanzhi, Gu, Ruolei, Kong, Yazhuo, Hu, Li. Sex difference in trait empathy is encoded in the human anterior insula. CEREBRAL CORTEX[J]. 2023, 33(9): 5055-5065, http://dx.doi.org/10.1093/cercor/bhac398.
[5] Wu, Xiao, Wang, Xiao, Lu, XueJing, Kong, YaZhuo, Hu, Li. Enhanced neural synchrony associated with long-term ballroom dance training. NEUROIMAGE[J]. 2023, 278: 12-, http://dx.doi.org/10.1016/j.neuroimage.2023.120301.
[6] Guo,Guangxin, Kong,Yazhuo, Zhu,Qingguang, Wu,Zhiwei, Zhang,Shuaipan, Sun,Wuquan, Cheng,Yanbin, Fang,Min. Cerebral mechanism of Tuina analgesia in management of knee osteoarthritis using multimodal MRI: study protocol for a randomised controlled trial. TRIALS[J]. 2022, 23(1): 13-, https://doaj.org/article/a3c62e3bd51b4861a9ec2201af9ed9f5.
[7] Kossowski, Bartosz, Kong, Yazhuo, KlimiecMoskal, Elzbieta, Emir, Uzay, Palace, Jacqueline, Jurynczyk, Maciej. Relapsing antibody-negative patients with features of neuromyelitis optica spectrum disorders: Differences in N-acetylaspartate level in the cervical spinal cord indicate distinct underlying processes. MULTIPLE SCLEROSIS JOURNAL[J]. 2022, [8] Hong, Jiahui, Sun, Jingqing, Zhang, Liping, Tan, Zhongjian, Chen, Ying, Chen, Qiuyi, Zhu, Yupu, Liu, Yuhan, Zhu, Liying, Zeng, Lin, Kong, Yazhuo, Li, Bin, Liu, Lu. Neurological mechanism and treatment effects prediction of acupuncture on migraine without aura: Study protocol for a randomized controlled trial. FRONTIERS IN NEUROLOGY[J]. 2022, 13: http://dx.doi.org/10.3389/fneur.2022.981752.
[9] Ming Zhang, Ziyan Yang, Jiahui Zhong, Yuqi Zhang, Xiaomin Lin, Huajian Cai, Yazhuo Kong. Thalamocortical mechanisms for nostalgia-induced analgesia. JOURNAL OF NEUROSCIENCE[J]. 2022, https://www.jneurosci.org/content/early/2022/02/15/JNEUROSCI.2123-21.2022.
[10] Li-Bo Zhang, Xue-Jing Lu, Gan Huang, Hui-Juan Zhang, Yi-Heng Tu, Yazhuo Kong, Li Hu. Selective and replicable neuroimaging-based indicators of pain discriminability. Cell Reports Medicine[J]. 2022, 3(12): 100846-, https://doi.org/10.1016/j.xcrm.2022.100846.
[11] Zhao, Qing, Kong, Yazhuo, Wan, Li. Editorial: Pain and Depression. FRONTIERS IN PSYCHOLOGY[J]. 2022, 13: http://dx.doi.org/10.3389/fpsyg.2022.865071.
[12] Jurynczyk, Maciej, KlimiecMoskal, Elzbieta, Kong, Yazhuo, Hurley, Samuel, Messina, Silvia, Yeo, Tianrong, Jenkinson, Mark, Leite, Maria Isabel, Palace, Jacqueline. Elucidating distinct clinico-radiologic signatures in the borderland between neuromyelitis optica and multiple sclerosis. JOURNAL OF NEUROLOGY[J]. 2022, 269(1): 269-279, http://dx.doi.org/10.1007/s00415-021-10619-1.
[13] Zhang, LiBo, Lu, XueJing, Huang, Gan, Zhang, Hui Juan, Tu, YiHeng, Kong, YaZhuo, Hu, Li. Selective and replicable neuroimaging-based indicators of pain discriminability. CELL REPORTS MEDICINE[J]. 2022, 3(12): http://dx.doi.org/10.1016/j.xcrm.2022.100846.
[14] Lu Liu, TianLi Lyu, MingYang Fu, LinPeng Wang, Ying Chen, JiaHui Hong, QiuYi Chen, YuPu Zhu, ZhongJian Tan, DaPeng Liu, ZiWei Chen, YaZhuo Kong, Bin Li. Changes in brain connectivity linked to multisensory processing of pain modulation in migraine with acupuncture treatment. NEUROIMAGE: CLINICAL[J]. 2022, 36: 103168-, http://dx.doi.org/10.1016/j.nicl.2022.103168.
[15] Peter Foley, Yazhuo Kong, Ramune Dirvanskiene, Maria valdesHernandez, Matteo Bastiani, Jonathan Murnane, Robin Sellar, Neil Roberts, Cyril Pernet, Christopher Weir, Thomas Bak, Lesley Colvin, Siddharthan Chandran, Marie Fallon, Irene Tracey. Coupling cognitive and brainstem dysfunction in multiple sclerosis-related chronic neuropathic limb pain. BRAIN COMMUNICATIONS[J]. 2022, 4(3): [16] Li, Hong, Li, Xiaoyun, Wang, Jiyuan, Gao, Fei, Wiech, Katja, Li Hu, Kong, Yazhuo. Pain-related reorganization in the primary somatosensory cortex of patients with postherpetic neuralgia. HUMAN BRAIN MAPPING[J]. 2022, http://dx.doi.org/10.1002/hbm.25992.
[17] Ming Zhang, Yang, Ziyan, Jiahui Zhong, Zhang, Yuqi, Lin, Xiaomin, Wang, Jiyuan, 蔡华俭, Kong, Yazhuo. The analgesic effect of nostalgia elicited by idiographic and nomothetic approaches on thermal stimulus. Annals of the New York Academy of Sciences[J]. 2022, [18] Wu, Xiao, Lu, Xuejing, Zhang, Huijuan, Wang, Xiao, Kong, Yazhuo, Hu, Li. The association between ballroom dance training and empathic concern: Behavioral and brain evidence. HUMAN BRAIN MAPPING[J]. 2022, 12-, https://doi.org/10.1002/hbm.26042.
[19] Zhao, Qing, Kong, Yazhuo, Wan, Li. Pain and Depression. 2022, [20] Li, Hong, Song, Qiaoyan, Zhang, Ruya, Zhou, Youlong, Kong, Yazhuo. Enhanced Temporal Coupling between Thalamus and Dorsolateral Prefrontal Cortex Mediates Chronic Low Back Pain and Depression. NEURAL PLASTICITY[J]. 2021, 2021: http://dx.doi.org/10.1155/2021/7498714.
[21] Bi, Yanzhi, Wei, Zhaoxing, Kong, Yazhuo, Hu, Li. Supraspinal neural mechanisms of the analgesic effect produced by transcutaneous electrical nerve stimulation. BRAIN STRUCTURE & FUNCTION[J]. 2021, 226(1): 151-162, http://dx.doi.org/10.1007/s00429-020-02173-9.
[22] Zhang, Ming, Zhang, Yuqi, Mu, Yan, Wei, Zhaoxing, Kong, Yazhuo. Gender discrimination facilitates fMRI responses and connectivity to thermal pain. NEUROIMAGE[J]. 2021, 244: 9-, http://dx.doi.org/10.1016/j.neuroimage.2021.118644.
[23] Jurynczyk, Maciej, KlimiecMoskal, Elzbieta, Kong, Yazhuo, Hurley, Samuel, Messina, Silvia, Yeo, Tianrong, Jenkinson, Mark, Leite, Maria Isabel, Palace, Jacqueline. Elucidating distinct clinico-radiologic signatures in the borderland between neuromyelitis optica and multiple sclerosis. JOURNAL OF NEUROLOGY[J]. 2021, 11-, [24] Tu, Yiheng, Zhang, Yuqi, Li, Yu, Zhao, Qing, Bi, Yanzhi, Lu, Xuejing, Kong, Yazhuo, Wang, Li, Lu, Zhijie, Hu, Li. Post-traumatic stress symptoms in COVID-19 survivors: a self-report and brain imaging follow-up study. MOLECULAR PSYCHIATRY[J]. 2021, 1-6, http://dx.doi.org/10.1038/s41380-021-01223-w.
[25] Mariano, Romina, Messina, Silvia, RocaFernandez, Adriana, Leite, Maria, I, Kong, Yazhuo, Palace, Jacqueline A. Quantitative spinal cord MRI in MOG-antibody disease, neuromyelitis optica and multiple sclerosis. BRAIN[J]. 2021, 144: 198-212, http://dx.doi.org/10.1093/brain/awaa347.
[26] Tackley, George, Kong, Yazhuo, Minne, Rachel, Messina, Silvia, Winkler, Anderson, Cavey, Ana, Everett, Rosie, DeLuca, Gabriele C, Weir, Andrew, Craner, Matthew, Tracey, Irene, Palace, Jacqueline, Stagg, Charlotte J, Emir, Uzay. An In-vivo 1H-MRS short-echo time technique at 7T: Quantification of metabolites in chronic multiple sclerosis and neuromyelitis optica brain lesions and normal appearing brain tissue. NEUROIMAGE[J]. 2021, 238: http://dx.doi.org/10.1016/j.neuroimage.2021.118225.
[27] Zhang, Ming, Zhang, Yuqi, Li, Zhihui, Hu, Li, Kong, Yazhuo. Sexism-Related Stigma Affects Pain Perception. NEURAL PLASTICITY[J]. 2021, 2021: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019650/.
[28] Wei, Zhaoxing, Zhang, Ming, Kong, Yazhuo. Neural similarities and differences between pain and itch: Reception, transmission and modulation. CHINESE SCIENCE BULLETIN-CHINESE[J]. 2020, 65(16): 1556-1568, [29] Ming Zhang, Yuqi Zhang, Yazhuo Kong. Interaction between social pain and physical pain. BRAIN SCIENCE ADVANCES[J]. 2020, 5(4): 265–273-, http://bsa.tsinghuajournals.com/EN/10.26599/BSA.2019.9050023.
[30] 张明, 穆妍, 章玉琪, 孔亚卓. 污名化对被污名个体人际互动的影响. 心理科学进展[J]. 2020, 28(9): 1564-1574, http://www.chinaxiv.org/abs/202005.00049.
[31] Bi, Yanzhi, Wei, Zhaoxing, Kong, Yazhuo, Hu, Li. Supraspinal neural mechanisms of the analgesic effect produced by transcutaneous electrical nerve stimulation. BRAIN STRUCTURE & FUNCTION[J]. 2020, 12-, [32] Wang, Ting, Lian, Zhiyun, Wu, Xi, Kong, Yazhuo, Zhou, Hongyu, Wei, Min. Subcortical structural abnormalities in female neuromyelitis optica patients with neuropathic pain. MULTIPLE SCLEROSIS AND RELATED DISORDERS[J]. 2020, 37: http://dx.doi.org/10.1016/j.msard.2019.101432.
[33] Li, Hong, Li, Xiaoyun, Feng, Yi, Gao, Fei, Kong, Yazhuo, Hu, Li. Deficits in ascending and descending pain modulation pathways in patients with postherpetic neuralgia. NEUROIMAGE[J]. 2020, 221: https://doaj.org/article/37fc48218aa24d2595088b4db80f2d8e.
[34] Wei Zhaoxing, Zhang Ming, Kong Yazhuo. Neural similarities and differences between pain and itch: Reception, transmission and modulation. KEXUE TONGBAO/CHINESE SCIENCE BULLETIN[J]. 2020, 65(16): 1556-1568,, http://www.irgrid.ac.cn/handle/1471x/6927277.
[35] Chen, Xiaoming, Li, Hong, Zhang, Qian, Wang, Jiye, Zhang, Wenbin, Liu, Jian, Li, Baojuan, Xin, Zhenlong, Liu, Jie, Yin, Hong, Chen, Jingyuan, Kong, Yazhuo, Luo, Wenjing. Combined fractional anisotropy and subcortical volumetric abnormalities in healthy immigrants to high altitude: A longitudinal study. HUMAN BRAIN MAPPING[J]. 2019, 40(14): 4202-4212, http://dx.doi.org/10.1002/hbm.24696.
[36] Ming Zhang, Yuqi Zhang, Yazhuo Kong. Interaction between social pain and physical pain. 神经科学(英文)[J]. 2019, 265-273, http://lib.cqvip.com/Qikan/Article/Detail?id=00002G8CKJ3G7JP167DO5JP1MHR.
[37] Eippert, Falk, Kong, Yazhuo, Winkler, Anderson M, Andersson, Jesper L, Finsterbusch, Juergen, Buechel, Christian, Brooks, Jonathan C W, Tracey, Irene. Investigating resting-state functional connectivity in the cervical spinal cord at 3 T. NEUROIMAGE[J]. 2017, 147: 589-601, http://dx.doi.org/10.1016/j.neuroimage.2016.12.072.
[38] Tseng, MingTsung, Kong, Yazhuo, Eippert, Falk, Tracey, Irene. Determining the Neural Substrate for Encoding a Memory of Human Pain and the Influence of Anxiety. JOURNAL OF NEUROSCIENCE[J]. 2017, 37(49): 11806-11817, http://dx.doi.org/10.1523/JNEUROSCI.0750-17.2017.
[39] Eippert Falk, Kong Yazhuo, Jenkinson Mark, Tracey Irene, Brooks Jonathan C W. Denoising spinal cord fIVIRI data: Approaches to acquisition and analysis. NEUROIMAGE[J]. 2017, 154: 255-266, [40] 孔亚卓. Investigating resting-state functional connectivity in the cervical spinal cord at 3T. NeuroImage. 2016, [41] Kong, Yazhuo, Okoruwa, Helen, Revis, Jon, Tackley, George, Leite, Maria Isabel, Lee, Michael, Tracey, Irene, Palace, Jacqueline. Pain in patients with transverse myelitis and its relationship to aquaporin 4 antibody status. JOURNAL OF THE NEUROLOGICAL SCIENCES[J]. 2016, 368: 84-88, http://dx.doi.org/10.1016/j.jns.2016.06.041.
[42] Kong, Yazhuo, Jenkinson, Mark, Andersson, Jesper, Tracey, Irene, Brooks, Jonathan C W. Assessment of physiological noise modelling methods for functional imaging of the spinal cord. NEUROIMAGE[J]. 2012, 60(2): 1538-1549, http://dx.doi.org/10.1016/j.neuroimage.2011.11.077.
[43] Wei, Pengxu, Li, Jianjun, Gao, Feng, Ye, Derong, Zhong, Qin, Liu, Shujia. Resting state networks in human cervical spinal cord observed with fMRI. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY[J]. 2010, 108(2): 265-271, https://www.webofscience.com/wos/woscc/full-record/WOS:000273174700006.

科研活动

   
科研项目
( 1 ) 中国科学院****(B类), 主持, 部委级, 2016-12--2021-11