郭靖涛  男    中国科学院动物研究所
电子邮件: jingtao.guo@ioz.ac.cn
通信地址: 北京市朝阳区北辰西路1号院5号中国科学院动物研究所干细胞与生殖生物学国家重点实验室
邮政编码: 100101

招生信息

   
招生专业
071008-发育生物学
071009-细胞生物学
0710Z1-基因组学
招生方向
发育生物学
生殖生物学
基因组学

教育背景

2013-08--2018-06   犹他大学医学院   博士
2009-09--2013-07   北京大学生命科学学院   理学学士

工作经历

   
工作简历
2021-12~现在, 中国科学院动物研究所, 研究员
2020-07~2021-11,犹他大学医学院, 助理教授
2018-08~2020-07,犹他大学医学院, 博士后

出版信息

   
发表论文
[1] Xichen Nie, Sarah K Munyoki, Meena Sukhwani, Nina Schmid, Annika Missel, Benjamin R Emery, DonorConnect, JanBernd Stukenborg, Artur Mayerhofer, Kyle E Orwig, Kenneth I Aston, James M Hotaling, Bradley R Cairns, Jingtao Guo. Single-cell analysis of human testis aging and correlation with elevated body mass index. DEVELOPMENTAL CELL[J]. 2022, 第 14 作者  通讯作者  57(9): 1160-1176.e5, https://doi.org/10.1016/j.devcel.2022.04.004.
[2] Grow, Edward J, Weaver, Bradley D, Smith, Christina M, Guo, Jingtao, Stein, Paula, Shadle, Sean C, Hendrickson, Peter G, Johnson, Nicholas E, Butterfield, Russell J, Menafra, Roberta, Kloet, Susan L, van der Maarel, Silvere M, Williams, Carmen J, Cairns, Bradley R. p53 convergently activates Dux/DUX4 in embryonic stem cells and in facioscapulohumeral muscular dystrophy cell models. NATURE GENETICS[J]. 2021, 第 4 作者53(8): 1207-1220, http://dx.doi.org/10.1038/s41588-021-00893-0.
[3] Mahyari, Eisa, Guo, Jingtao, Lima, Ana C, Lewinsohn, Daniel P, Stendahl, Alexandra M, VighConrad, Katinka A, Nie, Xichen, Nagirnaja, Liina, Rockweiler, Nicole B, Carrell, Douglas T, Hotaling, James M, Aston, Kenneth, I, Conrad, Donald F. Comparative single-cell analysis of biopsies clarifies pathogenic mechanisms in Klinefelter syndrome. AMERICAN JOURNAL OF HUMAN GENETICS[J]. 2021, 第 2 作者  通讯作者  108(10): 1924-1945, http://dx.doi.org/10.1016/j.ajhg.2021.09.001.
[4] Guo, Jingtao, Sosa, Enrique, Chitiashvili, Tsotne, Nie, Xichen, Rojas, Ernesto Javier, Oliver, Elizabeth, Plath, Kathrin, Hotaling, James M, Stukenborg, JanBernd, Clark, Amander T, Cairns, Bradley R, DonorConnect. Single-cell analysis of the developing human testis reveals somatic niche cell specification and fetal germline stem cell establishment. CELL STEM CELL[J]. 2021, 第 1 作者  通讯作者  28(4): 764-778, http://dx.doi.org/10.1016/j.stem.2020.12.004.
[5] Guo, Jingtao, Nie, Xichen, Giebler, Maria, Mlcochova, Hana, Wang, Yueqi, Grow, Edward J, DonorConnect, Kim, Robin, Tharmalingam, Melissa, Matilionyte, Gabriele, Lindskog, Cecilia, Carrell, Douglas T, Mitchell, Rod T, Goriely, Anne, Hotaling, James M, Cairns, Bradley R. The Dynamic Transcriptional Cell Atlas of Testis Development during Human Puberty. CELL STEM CELL[J]. 2020, 第 1 作者26(2): 262-276, http://dx.doi.org/10.1016/j.stem.2019.12.005.
[6] Patrick J Murphy, Jingtao Guo, Timothy G Jenkins, Emma R James, John R Hoidal, Thomas Huecksteadt, Dallin S Broberg, James M Hotaling, David F Alonso, Douglas T Carrell, Bradley R Cairns, Kenneth I Aston. NRF2 loss recapitulates heritable impacts of paternal cigarette smoke exposure. PLOS GENETICS[J]. 2020, 第 2 作者16(6): https://doaj.org/article/f1c39d09b6eb4aa9abd6df5fcde7696e.
[7] Guo Jingtao. Isolation and Enrichment of Spermatogonial Stem Cells from Human Testis Tissues. Current Protocols in Stem Cell Biology. 2019, 第 1 作者
[8] Guo, Jingtao, Grow, Edward J, Mlcochova, Hana, Maher, Geoffrey J, Lindskog, Cecilia, Nie, Xichen, Guo, Yixuan, Takei, Yodai, Yun, Jina, Cai, Long, Kim, Robin, Carrell, Douglas T, Goriely, Anne, Hotaling, James M, Cairns, Bradley R. The adult human testis transcriptional cell atlas. CELL RESEARCH[J]. 2018, 第 1 作者28(12): 1141-1157, http://lib.cqvip.com/Qikan/Article/Detail?id=6100228435.
[9] Guo, Jingtao, Grow, Edward J, Yi, Chongil, Mlcochova, Hana, Maher, Geoffrey J, Lindskog, Cecilia, Murphy, Patrick J, Wike, Candice L, Carrell, Douglas T, Goriely, Anne, Hotaling, James M, Cairns, Bradley R. Chromatin and Single-Cell RNA- Seq Profiling Reveal Dynamic Signaling and Metabolic Transitions during Human Spermatogonial Stem Cell Development. CELL STEM CELL[J]. 2017, 第 1 作者21(4): 533-+, http://dx.doi.org/10.1016/j.stem.2017.09.003.
发表著作
(1) The Potential of CRISPR/Cas Gene Editing to Correct Male Infertility, Springer, 2020-03, 第 2 作者