电子邮件： jibaoxia@licp.cas.cn
通信地址： 苏州市苏州工业园区金鸡湖大道99号
邮政编码： 215123
研究领域
Homogeneous Catalysis，Catalytic Oxo Synthesis and Transformations:
l Activation of small C1 molecules (CO and CO2) and inert chemical bonds (C–H and C–N) and their catalytic transformations
l Discovery of new synthetic methodologies and their applications in the synthesis of biologically active small molecules
招生信息
欢迎热爱化学的硕士研究生报考我们课题组的博士研究生；招收对我们在研方向感兴趣的联合培养硕士生和博士生。课题组有固定职工职位：实习研究员（学士和硕士）和助理研究员（博士）；课题组招收博士后；有意者请直接联系夏老师（jibaoxia@licp.cas.cn）。
招生专业
招生方向
教育背景
工作经历
工作简历
出版信息
43. Li, W.-D.; Wu, Y.; Li, S.-J.; Jiang, Y.-Q.; Li, Y.-L.; Lan, Y.; Xia, J.-B. Boryl Radical Activation of Aliphatic C−OH Bond: Cross-Electrophile Coupling of Free Alcohols and CO2 via Photoredox Catalysis. J. Am. Chem. Soc. 2022, 144, 8551-8559.
l Front Cover.
42. Li, W.-D.; Jiang, Y.-Q.; Li, Y.-L.; Xia, J.-B. Photoredox Ni-Catalyzed Selective Couping of Organic Halides and Oxalates to Esters via Alkoxycarbonyl Radical Intermediates. CCS Chem. 2022, 4, 1326-1336.
41. Gu, Z.-Y.; Xia, J.-B. [3+1+1] Cyclization of Vinyl Oxiranes with Azides and CO by Tandem Palladium Catalysis: Efficient Synthesis of Oxazolidinones. Org. Chem. Front. 2021, 8, 4112-4117.
40. Jiang, Y.-Q.; Gu, Z.-Y.; Chen, Y.; Xia, J.-B. Pd-Catalyzed Amidation of Silyl Enol Ethers with CO and Azides via an Isocyanate Intermediate. Asian. J. Org. Chem. 2021, 10, 1704-1707.
39. Li, Y.-L.; Zhang, S.-Q.; Chen, J.; Xia, J.-B. Highly Regio- and Enantioselective Reductive Coupling of Alkynes and Aldehydes via Photoredox Cobalt Dual Catalysis. J. Am. Chem. Soc. 2021, 143, 7306-7313.
l Highlighted in Chin. J. Org. Chem. 2021, 41, 3342-3343.
l Highlighted in Org. Chem. Highlights.
l Highlighted in Org. Chem. Portal.
38. Gu, Z.-Y.; Wu, Y.; Jin, F.; Bao, X.; Xia, J.-B. Palladium-Catalyzed Selective Intermolecular C–H Amidation of Alkenes with Carbon Monoxide and Azides. Synthesis 2021, 53, 3361-3371.
l Invited article for the special issue of ‘‘Bond Activation in Honor of Prof. Shinji Murai’’.
37. Gu, Z.-Y.; Han, H; Li, Z.; Ji, S.-J.; Xia, J.-B. Catalytic Synthesis of Functionalized Amidines via Cobalt-Carbene Radical Coupling with Isocyanides and Amines. Org. Chem. Front. 2021, 8, 1544-1550.
36. Li, W.-D.; Chen, J.; Zhu, D.-Y.; Xia, J.-B. Fe-Catalyzed Pictet-Spengler-type Cyclization via Selective Four-electron Reductive Functionalization of CO2. Chin. J. Chem. 2021, 39, 614-620.
35. Li, Y.-L.; Gu, Z.-Y.; Xia, J.-B. Transition-Metal-Catalyzed Intermolecular C–H Carbonylation toward Amides. Synlett 2021, 32, 7-13.
l Invited Synpacts Article.
34. Li, W.-D.; Xia, J.-B. 1,5-Hydrogen Atom Transfer Promoted Remote C–H Carboxylation. Chin. J. Org. Chem. 2020, 40, 4375-4376.
33. Zhang, Z.-B.; Xia, J.-B. Recent Advance in Transition-Metal-Catalyzed Transformations of Aromatic Amines via Neutral C–N Bond Cleavage. J. Mol. Catal. (China) 2020, 34, 569-578.
l Invited review on homogeneous catalysis.
32. Zhang, Z.-B.; Xia, J.-B. NHC-Nickel Catalyzed C−N Bond Cleavage of Mono-Protected Anilines for C−C Cross-Coupling. Org. Lett. 2020, 22, 9609-9613.
31. Guo, X.; Wu, Y.; Li, G.-Q.; Xia, J.-B. Redox-Triggered Ruthenium-Catalyzed Remote C–H Acylation with Primary Alcohols. ACS Catal. 2020, 10, 12987–12995.
30. Gu, Z.-Y.; Chen, J.; Xia, J.-B. Pd-Catalyzed Amidation of 1,3-Diketones with CO and Azides via a Nitrene Intermediate. Chem. Commun. 2020, 56, 11437-11440.
29. Guo, X.; Wang, Y.-Z.; Chen, J.; Li, G.-Q.; Xia, J.-B. Recent Advances of CO2 Fixation via Asymmetric Catalysis for the Direct Synthesis of Optically Active Small Molecules. Chin. J. Org. Chem. 2020, 40, 2208-2220.
l Invited review on C1 feedstock transformation.
28. Zhang, Z.-B.; Yang Y.; Yu, Z.-X.; Xia, J.-B. Lewis Base-Catalyzed Amino-Acylation of Arylallenes via C–N Bond Cleavage: Reaction Development and Mechanistic Studies. ACS Catal. 2020, 10, 5419-5429.
27. Li, Y.-L.; Li W.-D.; Gu, Z.-Y.; Chen, J.; Xia, J.-B. Photoredox Ni-catalyzed Branch-Selective Reductive Coupling of Aldehydes with 1,3-Dienes. ACS Catal. 2020, 10, 1528-1534.
26. Li, W.-D.; Zhu, D.-Y.; Li, G.; Chen, J.; Xia, J.-B. Iron-Catalyzed Selective N-Methylation and N-Formylation of Amines with CO2. Adv. Synth. Catal. 2019, 361, 5098-5104.
l VIP Paper; Front Cover
25. Yuan, S.-W.; Han, H.; Li, Y.-L.; Wu, X.; Bao, X.; Gu, Z.-Y.; Xia, J.-B. Intermolecular C–H Amidation of (Hetero)arenes to Produce Amides through Rhodium-Catalyzed Carbonylation of Nitrene Intermediate. Angew. Chem. Int. Ed. 2019, 58, 8887-8892.
l Highlighted in Chin. J. Org. Chem. 2019, 39, 2681.
24. Han, H.; Fang, L.; Chen, J.; Yang, S.-D.; Xia, J.-B. Tetramethylguanidine (TMG)-Catalyzed Reductive Spirocyclization of Tryptamine Derivatives with Formic Acid as a C1 Synthon. Tetrahedron Lett. 2019, 60, 1487-1489.
23. Han, H.; Zhang, T.; Yang, S.-D.; Lan, Y.; Xia, J.-B. Palladium-Catalyzed Enantioselective C–H Aminocarbonylation: Synthesis of Chiral Isoquinolinones. Org. Lett. 2019, 21, 1749-1754.
22. Han, H.; Yang, S.-D.; Xia, J.-B. Pd/Cu Cocatalyzed Oxidative Tandem C–H Aminocarbonylation and Dehydrogenation of Tryptamines: Synthesis of Carbolinones. J. Org. Chem. 2019, 84, 3357-3369.
21. Zhang, Z.-B.; Ji, C.-L.; Yang, C.; Chen, J.; Hong, X.; Xia, J.-B. Nickel-Catalyzed Kumada Coupling of Boc-Activated Aromatic Amines via Nondirected Selective Aryl C−N Bond Cleavage. Org. Lett. 2019, 21, 1226-1231.
l Highlighted in Synfacts 2019, 15, 526.
20. Li, G.; Chen, Y.; Xia, J.-B. Progress on Transition-Metal-Catalyzed Cross-coupling Reactions of Ammonium Salts via C–N Bond Cleavage. Chin. J. Org. Chem. 2018, 38, 1949-1962.
19. Li, G.; Chen, J.; Zhu, D.-Y.; Chen, Y.; Xia, J.-B. DBU-Catalyzed Selective N-Methylation and N-Formylation of Amines with CO2 and Polymethylhydrosiloxane. Adv. Synth. Catal. 2018, 360, 2364-2369.
18. Zhu, D.-Y.; Li, W.-D.; Yang, C.; Chen. J.; Xia, J.-B. Transition-Metal-Free Reductive Deoxygenative Olefination with CO2. Org. Lett. 2018, 20, 3282-3285.
17. Zhu, D.-Y.; Fang, L.; Han, H.; Wang Y.; Xia, J.-B. Reductive CO2 Fixation via Tandem C–C and C–N Bond Formation: Synthesis of Spiro-indolepyrrolidines. Org. Lett. 2017, 19, 4259-4262.
16. Zhu, D.-Y.; Chen, P.; Xia, J.-B. Synthesis of Planar Chiral Ferrocenes by Transition-Metal-Catalyzed Enantioselective C–H Activation. ChemCatChem, 2016, 8, 68-73.
Publications from Graduate and Postdoctoral Studies:
15. Han, L.; Xia, J.-B.; You, L.; Chen, C. Ketone-catalyzed photochemical C(sp3)–H chlorination. Tetrahedron 2017, 73, 3696-3701.
14. Xia, J.-B.; Zhu, C.; Chen, C. Visible Light-Promoted Metal-Free sp3-C–H Fluorination. Chem. Commun. 2014, 50, 11701-11704.
13. Xia, J.-B.; Ma, Y.; Chen, C. Vanadium-Catalyzed C(sp3)–H Fluorination Reactions. Org. Chem. Front. 2014, 1, 468-472.
l One of three hot articles in April, 2014.
l One of top ten most-read articles from April to June, 2014.
12. Zhu, C.; Xia, J.-B.; Chen, C. A Simple Method for the Electrophilic Cyanation of Secondary Amines. Org. Lett. 2014, 16, 247-250.
11. Zhu, C.; Xia, J.-B.; Chen, C. Vanadium-Catalyzed Oxidative Strecker Reaction: α-C–H Cyanation of para-Methoxyphenyl (PMP)-Protected Primary Amines. Tetrahedron Lett. 2014, 55, 232-234.
10. Xia, J.-B.; Zhu, C.; Chen, C. Visible Light-Promoted Metal-Free C–H Activation: Diarylketone-Catalyzed Selective Benzylic Mono- and Difluorination. J. Am. Chem. Soc. 2013, 135, 17494-17500.
l Highlighted in Synfacts 2014, 10, 85.
l Highlighted in Org. Chem. Front. 2014, 1, 434-438.
9. Xia, J.-B.; Cormier, K. W.; Chen, C. A Highly Selective Vanadium Catalyst for Benzylic C–H Oxidation. Chem. Sci. 2012, 3, 2240-2245.
l One of top ten most accessed articles in April, 2012.
8. Liu, W.-B.; Xia, J.-B.; You, S.-L. Iridium-Catalyzed Asymmetric Allylic Substitutions. Top. Organomet. Chem. 2012, 38, 155-208.
7. Xia, J.-B.; Liu, W.-B.; Wang, T.-M.; You, S.-L. Enantioselective Synthesis of 3-Azabicyclo[4.1.0]heptanes and 3-Azabicyclo[3.2.0]heptanes via Ir-Catalyzed Asymmetric Allylic Amination of N-Tosyl Propynylamine and Pt-Catalyzed Cycloisomerization Reaction. Chem. Eur. J. 2010, 16, 6442-6446.
l Highlighted in Synfacts 2010, 8, 909.
6. Xia, J.-B.; Zhuo, C.-X.; You, S.-L. Synthesis of Cyclopropane-containing Building Blocks via Ir-Catalyzed Enantioselective Allylic Substitution Reaction. Chin. J. Chem. 2010, 28, 1525-1528.
l Invited paper for celebrating the 60th Anniversary of SIOC.
5. You, S.-L.; Xia, J.-B. Palladium-Catalyzed Aryl–Aryl Bond Formation through Double C–H Activation. Top. Curr. Chem. 2010, 292, 165-194.
4. Xia, J.-B.; You, S.-L. Synthesis of 3-Haloindolizines by Copper(II) Halides Mediated Direct Functionalization of Indolizines. Org. Lett. 2009, 11, 1187-1190.
3. Xia, J.-B.; Wang, X.-Q.; You, S.-L. Synthesis of Biindolizines through Highly Regioselective Palladium-Catalyzed C–H Functionalization. J. Org. Chem. 2009, 74, 456-458.
2. Wang, X.-Q.; Xia, J.-B.; Dai, X.-Y.; You, S.-L. Preparation of Ferrocenyl Imidazolines using Bis(triphenyl)oxodiphosphonium Trifluoromethansulfonate. Sci. China Chem. 2009, 52, 1331-1336.
l Invited paper for the 90th Anniversary of Nankai University.
1. Xia, J.-B.; You, S.-L. Carbon–Carbon Bond Formation through Double sp2 C–H Activations: Synthesis of Ferrocenyl Oxazoline Derivatives. Organometallics 2007, 26, 4869-4871.
l One of the most-accessed articles in July-September 2007.
Book Chapters
2. Xia, J.-B.; You, S.-L. C–C Bond Formation via Double C–H Bond Activation. in Science of Synthesis, Yu, J.-Q., Ed, Thieme: Stuttgart, 2015 115-136.
1. Xia, J.-B.; Jamison, T. F.; You, S.-L. Monodentate Chiral Ferrocenyl Ligands. in Chiral Ferrocenes in Asymmetric Catalysis, Dai, L.-X., Hou, X.-L., Eds, WILEY-VCH: Weinheim, 2010, pp. 55-71.
科研活动
科研项目
指导学生
已指导学生
韩慧 博士研究生 070304-物理化学
张正兵 博士研究生 070303-有机化学
李彦霖 博士研究生 070303-有机化学
李文多 博士研究生 070303-有机化学
现指导学生
张士启 博士研究生 070303-有机化学
吴洋 博士研究生 070303-有机化学