基本信息

WANG JINHUI 男 博导 生命科学学院
电子邮件: wangjinhui@ucas.ac.cn
通信地址: 北京市朝阳区大屯路15号
邮政编码: 100101
电子邮件: wangjinhui@ucas.ac.cn
通信地址: 北京市朝阳区大屯路15号
邮政编码: 100101
研究领域
神经科学,生理学
招生信息
记忆细胞和环路的工作原理
招生专业
071006-神经生物学
招生方向
记忆细胞工作原理抑郁症神经环路机制神经细胞及突触信息编码的分子机制
教育背景
1989-08--1992-07 中国科学院上海生理研究所 博士
学历
中国科学院上海生理研究所 -- 研究生
学位
中国科学院上海生理研究所 -- 博士
工作经历
工作简历
2003-12~2025-09,中国科学院生物物理研究所;中国科学院大学, 研究员;特聘教授 博导1999-08~2004-08,University of Kansas, Assistant professor (tenure-track), 博导1994-05~1999-07,University of Texas, Houston Medical School, Research Scientist
社会兼职
2010-08-01-今,中国心理生理学会理事,
2010-05-31-今,中国神经药理学会常务理事,
2010-05-31-今,中国神经药理学会常务理事,
教授课程
高级生理学人体生理学(H)高等生理学人体生理学 (H)人体生理学神经生物学生理学普通生理学生物物理学系列讲座神经生理学
专利与奖励
奖励信息
(1) 国家杰出青年基金, , 国家级, 2003(2) 中国科学院BR计划, , 部委级, 2003
出版信息
发表论文
[1] WANG JINHUI. Associative memory neurons of encoding multi-modal signals are recruited by neuroligin-3 mediated new synapse formation.. eLife[J]. 2023, [2] WANG JINHUI. The interconnection and function of associative memory neurons are upregulated for memory strengthening.. Frontiers in Neural Circuits[J]. 2023, [3] Li, Bo, Zhang, Hao, Cao, Yi, Li, Zhao, Xu, Xinlei, Song, Zhenhua, Wang, Jinhui. Molecular changes in nucleus accumbens due to amelioration of depressive-like behavior by housing with companion. BRAIN RESEARCH BULLETIN[J]. 2022, 189: 34-43, http://dx.doi.org/10.1016/j.brainresbull.2022.08.010.[4] Zhenhua Song, Jinhui Wang. miRNA and mRNA Profiles in Ventral Tegmental Area From Juvenile Mice With Companion Communication of Improving CUMS-Induced Depression-Like Behaviors. FRONTIERS IN PSYCHIATRY,12,(2021-03-31). 2021, http://gooa.las.ac.cn/external/index?type=-1&pid=1737964.[5] Wu, Ruixiang, Cui, Shan, Wang, JinHui. miRNA-324/-133a essential for recruiting new synapse innervations and associative memory cells in coactivated sensory cortices. NEUROBIOLOGY OF LEARNING AND MEMORY[J]. 2020, 172: http://dx.doi.org/10.1016/j.nlm.2020.107246.[6] An, Tingting, Song, Zhenhua, Wang, Jinhui. Molecular mechanism of reward treatment ameliorating chronic stress-induced depressive-like behavior assessed by sequencing miRNA and mRNA in medial prefrontal cortex. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2020, 528(3): 520-527, http://dx.doi.org/10.1016/j.bbrc.2020.05.158.[7] WANG JINHUI. mRNA and microRNA profiles are associated with stress susceptibility and resilience induced by psychological stress in the prefrontal cortex.. PSYCHOPHARMACOLOGY. 2020, [8] Lu, Yanjun, Yang, Jiuyong, Sun, Jinyan, Lu, Wei, Wang, JinHui. mRNA and miRNA profiles in the nucleus accumbens are associated with psychological stress-induced susceptible and resilient mice. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR[J]. 2020, 199: http://dx.doi.org/10.1016/j.pbb.2020.173062.[9] Li Guo, Zhaoming Zhu, Guangyan Wang, Shan Cui, Meng Shen, Zhenhua Song, JinHui Wang. microRNA-15b contributes to depression-like behavior in mice by affecting synaptic protein levels and function in the nucleus accumbens. THE JOURNAL OF BIOLOGICAL CHEMISTRY. 2020, 295(20): 6831-6848, http://dx.doi.org/10.1074/jbc.RA119.012047.[10] Sun, Jinyan, Lu, Yanjun, Yang, Jiuyong, Song, Zhenhua, Lu, Wei, Wang, JinHui. mRNA and microRNA Profiles in the Amygdala Are Relevant to Susceptibility and Resilience to Psychological Stress Induced in Mice. JOURNAL OF MOLECULAR NEUROSCIENCE[J]. 2020, 70(11): 1771-1796, https://www.webofscience.com/wos/woscc/full-record/WOS:000532118700001.[11] Du, Kaixin, Lu, Wei, Sun, Yan, Feng, Jing, Wang, JinHui. mRNA and miRNA profiles in the nucleus accumbens are related to fear memory and anxiety induced by physical or psychological stress. JOURNAL OF PSYCHIATRIC RESEARCH[J]. 2019, 118: 44-65, http://dx.doi.org/10.1016/j.jpsychires.2019.08.013.[12] Gao, Zilong, Wu, Ruixiang, Chen, Changfeng, Wen, Bo, Liu, Yahui, Lu, Wei, Chen, Na, Feng, Jing, Fan, Ruichen, Wang, Dangui, Cui, Shan, Wang, JinHui. Coactivations of barrel and piriform cortices induce their mutual synapse innervations and recruit associative memory cells. BRAIN RESEARCH[J]. 2019, 1721: http://dx.doi.org/10.1016/j.brainres.2019.146333.[13] JinHui Wang. Searching basic units in memory traces: associative memory cells. F1000RESEARCH. 2019, 8: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509747/.[14] Sun, Yan, Lu, Wei, Du, Kaixin, Wang, JinHui. microRNA and mRNA profiles in the amygdala are relevant to fear memory induced by physical or psychological stress. JOURNAL OF NEUROPHYSIOLOGY[J]. 2019, 122(3): 1002-1022, [15] Shen, Mengmeng, Song, Zhenhua, Wang, JinHui. microRNA and mRNA profiles in the amygdala are associated with stress-induced depression and resilience in juvenile mice. PSYCHOPHARMACOLOGY[J]. 2019, 236(7): 2119-2142, https://www.webofscience.com/wos/woscc/full-record/WOS:000475575400012.[16] Sun, Xiaoyan, Song, Zhenhua, Si, Yawei, Wang, JinHui. microRNA and mRNA profiles in ventral tegmental area relevant to stress-induced depression and resilience. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY[J]. 2018, 86: 150-165, http://dx.doi.org/10.1016/j.pnpbp.2018.05.023.[17] Si, Yawei, Song, Zhenhua, Sun, Xiaoyan, Wang, JinHui. microRNA and mRNA profiles in nucleus accumbens underlying depression versus resilience in response to chronic stress. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS[J]. 2018, 177(6): 563-579, https://www.webofscience.com/wos/woscc/full-record/WOS:000442846000004.[18] JinHui Wang, Shan Cui. Associative memory cells and their working principle in the brain. F1000RESEARCH. 2018, 7: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806053/.[19] Jing Feng, Wei Lu, GuangYan Wang, ZhaoMing Zhu, Yan Sun, Kaixin Du, JinHui Wang. Cell-specific plasticity associated with integrative memory of triple sensory signals in the barrel cortex. ONCOTARGET. 2018, 9(57): 30962-30978, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089555/.[20] Zhao, Xin, Huang, Li, Guo, Rui, Liu, Yulong, Zhao, Shidi, Guan, Sudong, Ge, Rongjing, Cui, Shan, Wang, Shirlene, Wang, JinHui. Coordinated Plasticity among Glutamatergic and GABAergic Neurons and Synapses in the Barrel Cortex Is Correlated to Learning Efficiency. FRONTIERS IN CELLULAR NEUROSCIENCE[J]. 2017, 11: https://doaj.org/article/a032c302d337493f8a384af58cd944ee.[21] WANG JINHUI. Associative memory cells: Formation, function and perspectives. F1000Research. 2017, [22] Huang, Li, Wang, Chun, Zhao, Shidi, Ge, Rongjing, Guan, Sudong, Wang, JinHui. PKC and CaMK-II inhibitions coordinately rescue ischemia-induced GABAergic neuron dysfunction. ONCOTARGET[J]. 2017, 8(24): 39309-39322, https://www.webofscience.com/wos/woscc/full-record/WOS:000403311900104.[23] Zhu, Zhaoming, Wang, Guangyan, Ma, Ke, Cui, Shan, Wang, JinHui. GABAergic neurons in nucleus accumbens are correlated to resilience and vulnerability to chronic stress for major depression. ONCOTARGET[J]. 2017, 8(22): 35933-35945, https://www.webofscience.com/wos/woscc/full-record/WOS:000403230000041.[24] Liu, Yahui, Gao, Zilong, Chen, Changfeng, Wen, Bo, Huang, Li, Ge, Rongjing, Zhao, Shidi, Fan, Ruichen, Feng, Jing, Lu, Wei, Wang, Liping, Wang, JinHui. Piriform cortical glutamatergic and GABAergic neurons express coordinated plasticity for whisker-induced odor recall. ONCOTARGET[J]. 2017, 8(56): 95719-95740, https://www.webofscience.com/wos/woscc/full-record/WOS:000414937900054.[25] Guo, Rui, Ge, Rongjing, Zhao, Shidi, Liu, Yulong, Zhao, Xin, Huang, Li, Guan, Sodong, Lu, Wei, Cui, Shan, Wang, Shirlene, Wang, JinHui. Associative Memory Extinction Is Accompanied by Decayed Plasticity at Motor Cortical Neurons and Persistent Plasticity at Sensory Cortical Neurons. FRONTIERS IN CELLULAR NEUROSCIENCE[J]. 2017, 11: https://doaj.org/article/7ddfd05033284473921bd8db88986904.[26] Yang, Zhilai, Chen, Na, Ge, Rongjing, Qian, Hao, Wang, JinHui. Functional compatibility between Purkinje cell axon branches and their target neurons in the cerebellum. ONCOTARGET[J]. 2017, 8(42): 72424-72437, https://www.webofscience.com/wos/woscc/full-record/WOS:000411509400087.[27] Lu, Wei, Feng, Jing, Wen, Bo, Wang, Kewei, Wang, JinHui. Activity-induced spontaneous spikes in GABAergic neurons suppress seizure discharges: an implication of computational modeling. ONCOTARGET[J]. 2017, 8(20): 32384-32397, http://dx.doi.org/10.18632/oncotarget.15660.[28] Feng, Jing, Lu, Wei, Wang, Dangui, Ma, Ke, Song, Zhenhua, Chen, Na, Sun, Yan, Du, Kaixin, Shen, Mengmeng, Cui, Shan, Wang, JinHui. Barrel Cortical Neuron Integrates Triple Associated Signals for Their Memory Through Receiving Epigenetic-Mediated New Synapse Innervations. CEREBRAL CORTEX[J]. 2017, 27(12): 5858-5871, https://www.webofscience.com/wos/woscc/full-record/WOS:000416280200035.[29] Liu, Yulong, Ge, Rongjing, Zhao, Xin, Guo, Rui, Huang, Li, Zhao, Shidi, Guan, Sudong, Lu, Wei, Cui, Shan, Wang, Shirlene, Wang, JinHui. Activity strengths of cortical glutamatergic and GABAergic neurons are correlated with transgenerational inheritance of learning ability. ONCOTARGET[J]. 2017, 8(68): 112401-112416, https://www.webofscience.com/wos/woscc/full-record/WOS:000419569800021.[30] Lei, Zhuofan, Wang, Dangui, Chen, Na, Ma, Ke, Lu, Wei, Song, Zhenhua, Cui, Shan, Wang, JinHui. Synapse Innervation and Associative Memory Cell Are Recruited for Integrative Storage of Whisker and Odor Signals in the Barrel Cortex through miRNA-Mediated Processes. FRONTIERS IN CELLULAR NEUROSCIENCE[J]. 2017, 11: https://doaj.org/article/94677be70bca4cb3916136ba3d2adbfe.[31] Lei, Zhuofan, Liu, Bei, Wang, JinHui. Reward memory relieves anxiety-related behavior through synaptic strengthening and protein kinase C in dentate gyrus. HIPPOCAMPUS[J]. 2016, 26(4): 502-516, [32] Xu, Aiping, Cui, Shan, Wang, JinHui. Incoordination among Subcellular Compartments Is Associated with Depression-Like Behavior Induced by Chronic Mild Stress. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY[J]. 2016, 19(5): https://www.webofscience.com/wos/woscc/full-record/WOS:000377112900003.[33] Ma, Ke, Guo, Li, Xu, Aiping, Cui, Shan, Wang, JinHui. Molecular Mechanism for Stress-Induced Depression Assessed by Sequencing miRNA and mRNA in Medial Prefrontal Cortex. PLOS ONE[J]. 2016, 11(7): http://dx.doi.org/10.1371/journal.pone.0159093.[34] Ma, K, Xu, A, Cui, S, Sun, MR, Xue, YC, Wang, JH. Impaired GABA synthesis, uptake and release are associated with depression-like behaviors induced by chronic mild stress. TRANSLATIONAL PSYCHIATRY[J]. 2016, 6: https://www.webofscience.com/wos/woscc/full-record/WOS:000392130600005.[35] Gao, Zilong, Chen, Lei, Fan, Ruicheng, Lu, Wei, Wang, Dangui, Cui, Shan, Huang, Li, Zhao, Shidi, Guan, Sudong, Zhu, Yan, Wang, JinHui. Associations of Unilateral Whisker and Olfactory Signals Induce Synapse Formation and Memory Cell Recruitment in Bilateral Barrel Cortices: Cellular Mechanism for Unilateral Training Toward Bilateral Memory. FRONTIERS IN CELLULAR NEUROSCIENCE[J]. 2016, 10: https://doaj.org/article/2cd42a0169414b3ba3d4cf9da991c895.[36] Yan, Fenxia, Gao, Zilong, Chen, Pin, Huang, Li, Wang, Dangui, Chen, Na, Wu, Ruixiang, Feng, Jing, Cui, Shan, Lu, Wei, Wang, JinHui. Coordinated Plasticity between Barrel Cortical Glutamatergic and GABAergic Neurons during Associative Memory. NEURAL PLASTICITY[J]. 2016, 2016: https://doaj.org/article/dd35faa5371a48b9aa01ca8d81378604.[37] Wang, GuangYan, Zhu, ZhaoMing, Cui, Shan, Wang, JinHui. Glucocorticoid Induces Incoordination between Glutamatergic and GABAergic Neurons in the Amygdala. PLOS ONE[J]. 2016, 11(11): https://doaj.org/article/58efbe583b604396b653cdfb0f82cdc2.[38] Wang, Dangui, Zhao, Jun, Gao, Zilong, Chen, Na, Wen, Bo, Lu, Wei, Lei, Zhuofan, Chen, Changfeng, Liu, Yahui, Feng, Jing, Wang, JinHui. Neurons in the barrel cortex turn into processing whisker and odor signals: a cellular mechanism for the storage and retrieval of associative signals. FRONTIERS IN CELLULAR NEUROSCIENCE[J]. 2015, 9: https://doaj.org/article/524a85dbd7db4452b794f17ce3cf1c9d.[39] WANG JINHUI. Neuron-specific mechanisms for epilepsy self-termination. Molecular & Cellular Epilepsy. 2015, [40] WANG JINHUI. A portion of inhibitory neurons in human TLE are functionally upregulated: an endogenous mechanism for seizure termination.. 2015, [41] Li Huang, Shidi Zhao, Wei Lu, Sudong Guan, Yan Zhu, JinHui Wang. Acidosis-Induced Dysfunction of Cortical GABAergic Neurons through Astrocyte-Related Excitotoxicity. PLOS ONE[J]. 2015, 10(10): https://doaj.org/article/b44e3354ce00488eb1fbfa3d128ab9a5.[42] Wang, MingHui, Chen, Na, Wang, JinHui. The coupling features of electrical synapses modulate neuronal synchrony in hypothalamic superachiasmatic nucleus. BRAIN RESEARCH[J]. 2014, 1550: 9-17, http://dx.doi.org/10.1016/j.brainres.2014.01.007.[43] WANG JINHUI. Protein kinase C is essential for kainate-induced anxiety-like behavior and glutamatergic synapse upregulation in prefrontal cortex.. 2014, [44] Yang, Zhilai, Gu, Erwei, Lu, Xianfu, Wang, JinHui. Essential role of axonal VGSC inactivation in time-dependent deceleration and unreliability of spike propagation at cerebellar Purkinje cells. MOLECULAR BRAIN[J]. 2014, 7(1): 1-1, http://dx.doi.org/10.1186/1756-6606-7-1.[45] Lu, Wei, Wen, Bo, Zhang, Fengyu, Wang, JinHui. Voltage-independent sodium channels emerge for an expression of activity-induced spontaneous spikes in GABAergic neurons. MOLECULAR BRAIN[J]. 2014, 7(1): http://dx.doi.org/10.1186/1756-6606-7-38.[46] Ge, Rongjing, Qian, Hao, Chen, Na, Wang, JinHui. Input-dependent subcellular localization of spike initiation between soma and axon at cortical pyramidal neurons. MOLECULAR BRAIN[J]. 2014, 7(1): http://dx.doi.org/10.1186/1756-6606-7-26.[47] Yang, Zhilai, Wang, JinHui. Frequency-Dependent Reliability of Spike Propagation Is Function of Axonal Voltage-Gated Sodium Channels in Cerebellar Purkinje Cells. CEREBELLUM[J]. 2013, 12(6): 862-869, [48] Zhang, Guanjun, Gao, Zilong, Guan, Sudong, Zhu, Yan, Wang, JinHui. Upregulation of excitatory neurons and downregulation of inhibitory neurons in barrel cortex are associated with loss of whisker inputs. MOLECULAR BRAIN[J]. 2013, 6(1): 2-2, http://www.irgrid.ac.cn/handle/1471x/756605.[49] Zhao, Jun, Wang, Dangui, Wang, JinHui. Barrel cortical neurons and astrocytes coordinately respond to an increased whisker stimulus frequency. MOLECULAR BRAIN[J]. 2012, 5(1): 12-12, http://www.irgrid.ac.cn/handle/1471x/756722.[50] Bing Ye, Li Huang, Zilong Gao, Ping Chen, Hong Ni, Sudong Guan, Yan Zhu, JinHui Wang. The Functional Upregulation of Piriform Cortex Is Associated with Cross-Modal Plasticity in Loss of Whisker Tactile Inputs. PLOS ONE[J]. 2012, 7(8): http://www.irgrid.ac.cn/handle/1471x/756959.[51] WANG JINHUI. mGluR activation improves network asynchrony and GABAergic synapse attenuation in the amygdala: Implication for anxiety-like behavior in DAB/2 mice.. Molecular Brain. 2012, [52] Yu, Jiandong, Qian, Hao, Wang, JinHui. Upregulation of transmitter release probability improves a conversion of synaptic analogue signals into neuronal digital spikes. MOLECULAR BRAIN[J]. 2012, 5(1): 26-26, http://dx.doi.org/10.1186/1756-6606-5-26.[53] Ge, Rongjing, Qian, Hao, Wang, JinHui. Physiological synaptic signals initiate sequential spikes at soma of cortical pyramidal neurons. MOLECULAR BRAIN[J]. 2011, 4(1): 19-19, http://dx.doi.org/10.1186/1756-6606-4-19.[54] Jiandong Yu, Hao Qian, Na Chen, JinHui Wang. Quantal Glutamate Release Is Essential for Reliable Neuronal Encodings in Cerebral Networks. PLOS ONE[J]. 2011, 6(9): https://doaj.org/article/f6cc3efb1ee044d3ab0c5010031bbc45.[55] Ni, Hong, Huang, Li, Chen, Na, Zhang, Fengyu, Liu, Dongbo, Ge, Ming, Guan, Sudong, Zhu, Yan, Wang, JinHui. Upregulation of Barrel GABAergic Neurons Is Associated with Cross-Modal Plasticity in Olfactory Deficit. PLOS ONE[J]. 2010, 5(10): http://www.irgrid.ac.cn/handle/1471x/757177.[56] Na Chen, Jiandong Yu, Hao Qian, Rongjing Ge, JinHui Wang. Axons Amplify Somatic Incomplete Spikes into Uniform Amplitudes in Mouse Cortical Pyramidal Neurons. PLOS ONE[J]. 2010, 5(7): http://www.irgrid.ac.cn/handle/1471x/757188.[57] Huang, Li, Chen, Na, Ge, Ming, Zhu, Yan, Guan, Sudong, Wang, JinHui. Ca2+ and acidosis synergistically lead to the dysfunction of cortical GABAergic neurons during ischemia. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2010, 394(3): 709-714, http://www.irgrid.ac.cn/handle/1471x/757221.[58] Qi, Yulong, Huang, Li, Ni, Hong, Zhou, Xin, Zhang, Jing, Zhu, Yan, Ge, Ming, Guan, Sudong, Wang, JinHui. Intracellular Ca2+ regulates spike encoding at cortical GABAergic neurons and cerebellar Purkinje cells differently. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2009, 381(1): 129-133, http://www.irgrid.ac.cn/handle/1471x/757793.[59] Wang, Qiyi, Liu, Xiuping, Ge, Rongjing, Guan, Sudong, Zhu, Yan, Wang, JinHui. The postnatal development of intrinsic properties and spike encoding at cortical GABAergic neurons. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2009, 378(4): 706-710, http://www.irgrid.ac.cn/handle/1471x/757941.[60] Ge, Rongjing, Chen, Na, Wang, JinHui. Real-time neuronal homeostasis by coordinating VGSC intrinsic properties. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2009, 387(3): 585-589, http://www.irgrid.ac.cn/handle/1471x/757826.[61] Wang, JinHui, Wei, Jian, Chen, Xin, Yu, Jiandong, Chen, Na, Shi, Jack. Gain and fidelity of transmission patterns at cortical excitatory unitary synapses improve spike encoding. JOURNAL OF CELL SCIENCE[J]. 2008, 121(17): 2951-2960, http://www.irgrid.ac.cn/handle/1471x/757631.[62] Zhao, Shidi, Chen, Na, Yang, Zhilai, Huang, Li, Zhu, Yan, Guan, Sudong, Chen, Qianfen, Wang, JinHui. Ischemia deteriorates the spike encoding of rat cerebellar Purkinje cells by raising intracellular Ca2+. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2008, 366(2): 401-407, http://www.irgrid.ac.cn/handle/1471x/757691.[63] Chen, Na, Chen, Xin, Wang, JinHui. Homeostasis established by coordination of subcellular compartment plasticity improves spike encoding. JOURNAL OF CELL SCIENCE[J]. 2008, 121(17): 2961-2971, http://www.irgrid.ac.cn/handle/1471x/757632.[64] WANG JINHUI. Sodium channel-mediated intrinsic mechanisms underlying the di?erences of spike programming among GABAergic neurons.. Biochemical and Biophysical Research Communications. 2006, [65] Chen, N, Chen, SL, Wu, YL, Wang, JH. The refractory periods and threshold potentials of sequential spikes measured by whole-cell recording. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2006, 340(1): 151-157, https://www.webofscience.com/wos/woscc/full-record/WOS:000234640600023.[66] Guan, Sudong, Ma, Shanfeng, Zhu, Yan, Ge, Rongjin, Wang, Qiyi, Wang, JinHui. The intrinsic mechanisms underlying the maturation of programming sequential spikes at cerebellar Purkinje cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2006, 345(1): 175-180, https://www.webofscience.com/wos/woscc/full-record/WOS:000237877700025.[67] Chen, Na, Chen, Xin, Yu, Jiandong, Wang, Jinhui. Afterhyperpolarization improves spike programming through lowering threshold potentials and refractory periods mediated by voltage-gated sodium channels. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2006, 346(3): 938-945, https://www.webofscience.com/wos/woscc/full-record/WOS:000238865900042.[68] Guan, Sudong, Ma, Shanfeng, Zhu, Yan, Wang, Jinhui. The postnatal development of refractory periods and threshold potentials at cerebellar Purkinje neurons. BRAIN RESEARCH[J]. 2006, 1097(1): 59-64, http://dx.doi.org/10.1016/j.brainres.2006.04.092.[69] Wang, JH, Zhang, MJ. Differential modulation of glutamatergic and cholinergic synapses by calcineurin in hippocampal CA1 fast-spiking interneurons. BRAIN RESEARCH[J]. 2004, 1004(1-2): 125-135, http://dx.doi.org/10.1016/j.brainres.2004.01.025.[70] WANG JINHUI. Calcium signal- dependent multigrade-plasticity of neuronal excitability developed postnatally.. Journal of Neurobiology. 2004, [71] WANG JINHUI. Ca2+/CaM signal pathway up-regulates GABA synaptic function through cytoskeleton-mediated mechanisms.. 2004, [72] Wang, JH. Short-term cerebral ischemia causes the dysfunction of interneurons and more excitation of pyramidal neurons in rats. BRAIN RESEARCH BULLETIN[J]. 2003, 60(1-2): 53-58, http://dx.doi.org/10.1016/S0361-9230(03)00026-1.[73] WANG JINHUI. Ca2+/CaM signal pathway up-regulates glutamatergic synaptic function on non-pyramidal fast-spiking neurons in hippocampal CA1.. Journal of Physiology (London). 2001, [74] Wang, JH, Kelly, PT. Attenuation of paired-pulse facilitation associated with synaptic potentiation mediated by postsynaptic mechanisms. JOURNAL OF NEUROPHYSIOLOGY[J]. 1997, 78(5): 2707-2716, https://www.webofscience.com/wos/woscc/full-record/WOS:A1997YG93900044.[75] Wang, JH, Kelly, PT. Postsynaptic calcineurin activity downregulates synaptic transmission by weakening intracellular Ca2+ signaling mechanisms in hippocampal CA1 neurons. JOURNAL OF NEUROSCIENCE[J]. 1997, 17(12): 4600-4611, https://www.webofscience.com/wos/woscc/full-record/WOS:A1997XG31800011.[76] Wang, JH, Ko, GYP, Kelly, PT. Cellular and molecular bases of memory: Synaptic and neuronal plasticity. JOURNAL OF CLINICAL NEUROPHYSIOLOGY[J]. 1997, 14(4): 264-293, https://www.webofscience.com/wos/woscc/full-record/WOS:A1997YH52700002.[77] WANG JINHUI. Regulation of synaptic facilitation by postsynaptic Ca2+ -CaM signaling pathway in rat hippocampal CA1 neurons.. Journal of Neurophysiology. 1996, [78] WANG JINHUI. The balance between postsynaptic Ca2+-dependent protein kinases and phosphates controlling synaptic strength.. 1996, [79] Wang, JH, Stelzer, A. Shared calcium signaling pathways in the induction of long-term potentiation and synaptic disinhibition in CA1 pyramidal cell dendrites. JOURNAL OF NEUROPHYSIOLOGY[J]. 1996, 75(4): 1687-1702, https://www.webofscience.com/wos/woscc/full-record/WOS:A1996UE79800027.[80] WANG, JH, KELLY, PT. POSTSYNAPTIC INJECTION OF CA2+/CAM INDUCES SYNAPTIC POTENTIATION REQUIRING CAMKII AND PKC ACTIVITY. NEURON[J]. 1995, 15(2): 443-452, http://dx.doi.org/10.1016/0896-6273(95)90048-9.[81] WANG, JH, STELZER, A. INHIBITION OF PHOSPHATASE 2B PREVENTS EXPRESSION OF HIPPOCAMPAL LONG-TERM POTENTIATION. NEUROREPORT[J]. 1994, 5(17): 2377-2380, https://www.webofscience.com/wos/woscc/full-record/WOS:A1994PW54700041.[82] WANG JINHUI. Postsynaptic protein kinase C essential to both induction and maintenance of long-term potentiation in hippocampal CA1 region.. Proc. Natl. Acad. Sci. USA. 1992,
发表著作
(1) Associative Memory Cells: Basic Units of Memory Traces, Springer Nature, 2019-09, 第 1 作者
科研活动
科研项目
( 1 ) 中枢神经损伤修复与功能重建中胶质细胞的作用及意义, 参与, 国家级, 2011-01--2015-08( 2 ) 额叶和海马环路发育调控的分子机理, 主持, 国家级, 2010-01--2013-12( 3 ) 跨膜式神经可塑性动物模型在改善认知障碍中的机理和应用, 主持, 国家级, 2012-01--2015-12( 4 ) 奖励性记忆改善焦虑的细胞分子基础研究, 主持, 国家级, 2015-01--2018-12( 5 ) MDD神经环路异常及形成机制, 主持, 国家级, 2013-01--2017-08( 6 ) 用新信息记忆的动物模型研究认知障碍病理机制和防治策略, 主持, 国家级, 2017-01--2020-12( 7 ) 抑郁症亚型诊断及其防治疗效监测的生物标志物研究, 参与, 国家级, 2016-09--2020-12( 8 ) 增强大脑联合记忆细胞形成与维护拟改善认知障碍的研究, 主持, 国家级, 2020-01--2023-12
参与会议
(1)Associative memory extinction is accompanied by decays of associative memory cells and their plasticity at motor cortex but not sensory cortex 2017-11-11(2)Synapse formation and memory cell recruitment for associative memory 2016-11-12(3)Neuron-specific mechanisms for unilateral learning and bilateral memory recalls 2015-10-17(4)Cortical glutamatergic and GABAergic neurons learn to encode odor signal through their coordinated plasticity 2014-11-14(5)Neurons in barrel cortex turn into processing whisker and odor signals: a novel form of associative learning 2013-11-08(6)Functional compatibility between Purkinje cell axon branches and their target neurons in the cerebellum 2012-10-12(7)Anxiety-associated network asynchrony and GABAergic synapse attenuation in amygdala are improved by mGluR1.5 activation Fengyu Zhang, Bei Liu, Zhuofen Lei and Jinhui Wang 2011-11-12(8)Soma as a source to encode neuronal digital signals J. H. WANG 2010-10-17(9)How is neuronal homeostasis maintained J. H. WANG 2009-10-19(10)Axon facilitates the propagation of sequential spikes toward terminals to secure synaptic transmission J. H. WANG 2008-11-15(11)Ischemia deteriorates the spike encoding of cerebellar Purkinje cells via raising intracellular Ca2+ J. H. WANG 2007-11-05(12)Sodium channel-mediated intrinsic mechanisms navigate the programming of sequential spikes J. H. WANG 2006-10-17
指导学生
已指导学生
陈欣 博士研究生 071011-生物物理学
余建东 博士研究生 071011-生物物理学
王明辉 博士研究生 071010-生物化学与分子生物学
葛荣靖 博士研究生 071006-神经生物学
赵君 博士研究生 071006-神经生物学
杨志来 博士研究生 071006-神经生物学
雷卓凡 博士研究生 071006-神经生物学
温波 博士研究生 071006-神经生物学
钱浩 博士研究生 071006-神经生物学
卢炜 博士研究生 071006-神经生物学
高子龙 博士研究生 071006-神经生物学
郭莉 博士研究生 071006-神经生物学
吴瑞祥 博士研究生 071006-神经生物学
魏忠杰 硕士研究生 071006-神经生物学
现指导学生
肖华娟 博士研究生 071006-神经生物学
许杨 博士研究生 071010-生物化学与分子生物学
崔田亮 硕士研究生 071011-生物物理学
姜震 硕士研究生 085238-生物工程
张赟 博士研究生 071009-细胞生物学
李佳怡 硕士研究生 071009-细胞生物学
陈炳琛 博士研究生 071009-细胞生物学