Chen Chen Ph.D. Research Scientist
South China Botanical Garden
Chinese Academy of Science
Guangzhou
Email: chenchen101@scbg.ac.cn
Address: 723 Xinke Rd., Tianhe District, Guangzhou, China
Research Areas
Plant molecular biology, Transcription regulation,Epigenetics, Abiotic response of plants
Education
2012.01 to 2017.03, The University of Western Ontario, Canada. Doctor of Philosophy in Biology
2008.09 to 2011.12, Sun Yat-Sen University, China. Graduate Study
2002.09 to 2006.07, Yangzte University, China. Bachelor of Bioengineering
Experience
Work Experience
2020.05 to Now, South China Botanical Garden, Chinese Academy of Science. The Regulation of
Plant Adaptivity (Principal Investigator)
2017.04 to 2020.03, London Research and Developmental Centre, Agriculture and Agri-Food
Canada. Postdoc
Publications
[2] Han, Danlu, Chen, Chen, Xia, Simin, Liu, Jun, Shu, Jie, Nguyen, Vi, Lai, Jianbin, Cui, Yuhai, Yang, Chengwei. Chromatin-associated SUMOylation controls the transcriptional switch between plant development and heat stress responses. PLANT COMMUNICATIONS[J]. 2021, 2(1): 85-95, http://dx.doi.org/10.1016/j.xplc.2020.100091.
[3] Shu, Jie, Chen, Chen, Li, Chenlong, Thapa, Raj K, Song, Jingpu, Xie, Xin, Nguyen, Vi, Bian, Shaomin, Liu, Jun, Kohalmi, Susanne E, Cui, Yuhai. Genome-wide occupancy of Arabidopsis SWI/SNF chromatin remodeler SPLAYED provides insights into its interplay with its close homolog BRAHMA and Polycomb proteins. PLANT JOURNAL[J]. 2021, 106(1): 200-213, https://www.webofscience.com/wos/woscc/full-record/WOS:000629696000001.
[4] Song, Jingpu, Xie, Xin, Chen, Chen, Shu, Jie, Thapa, Raj K, Vi Nguyen, Bian, Shaomin, Kohalmi, Susanne E, Marsolais, Frederic, Zou, Jitao, Cui, Yuhai. LEAFY COTYLEDON1 expression in the endosperm enables embryo maturation in Arabidopsis. NATURE COMMUNICATIONS[J]. 2021, 12(1): https://doaj.org/article/13b68548dfb648608295fce354e3ee15.
[5] Jie Shu, Chen Chen, Susanne E Kohalmi, Yuhai Cui. Evidence that AGL17 is a significant downstream target of CLF in floral transition control. PLANT SIGNALING & BEHAVIOR[J]. 2020, 15(7): https://www.webofscience.com/wos/woscc/full-record/WOS:000534897800001.
[6] Hung, FuYu, Chen, Chen, Yen, MingRen, Hsieh, JoWei Allison, Li, Chenlong, Shih, YuanHsin, Chen, FangFang, Chen, PaoYang, Cui, Yuhai, Wu, Keqiang. The expression of long non-coding RNAs is associated with H3Ac and H3K4me2 changes regulated by the HDA6-LDL1/2 histone modification complex in Arabidopsis. NAR GENOMICS AND BIOINFORMATICS[J]. 2020, 2(3): http://dx.doi.org/10.1093/nargab/lqaa066.
[7] Shu, Jie, Chen, Chen, Li, Chenlong, Cui, Yuhai. The complexity of PRC2 catalysts CLF and SWN in plants. BIOCHEMICAL SOCIETY TRANSACTIONSnull. 2020, 48(6): 2779-2789, http://dx.doi.org/10.1042/BST20200660.
[8] Yu, Yaoguang, Liang, Zhenwei, Song, Xin, Fu, Wei, Xu, Jianqu, Lei, Yawen, Yuan, Liangbing, Ruan, Jiuxiao, Chen, Chen, Fu, Wenqun, Cui, Yuhai, Huang, Shangzhi, Li, Chenlong. BRAHMA-interacting proteins BRIP1 and BRIP2 are core subunits of Arabidopsis SWI/SNF complexes. NATURE PLANTS[J]. 2020, 6(8): 996-+, http://dx.doi.org/10.1038/s41477-020-0734-z.
[9] Shu, Jie, Chen, Chen, Thapa, Raj Kumar, Bian, Shaomin, Vi Nguyen, Yu, Kangfu, Yuan, ZeChun, Liu, Jun, Kohalmi, Susanne E, Li, Chenlong, Cui, Yuhai. Genome-wide occupancy of histone H3K27 methyltransferases CURLY LEAF and SWINGER in Arabidopsis seedlings. PLANT DIRECT[J]. 2019, 3(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000509897600007.
[10] Chen, Chen, Shu, Jie, Li, Chenlong, Thapa, Raj K, Vi Nguyen, Yu, Kangfu, Yuan, ZeChun, Kohalmi, Susanne E, Liu, Jun, Marsolais, Frederic, Huang, Shangzhi, Cui, Yuhai. RNA polymerase II-independent recruitment of SPT6L at transcription start sites in Arabidopsis. NUCLEIC ACIDS RESEARCH[J]. 2019, 47(13): 6714-6725, https://www.webofscience.com/wos/woscc/full-record/WOS:000490556600018.
[11] Li, Chenlong, Chen, Chen, Chen, Huhui, Wang, Suikang, Chen, Xuemei, Cui, Yuhai. Verification of DNA motifs in Arabidopsis using CRISPR/Cas9-mediated mutagenesis. PLANT BIOTECHNOLOGY JOURNAL[J]. 2018, 16(8): 1446-1451, https://www.webofscience.com/wos/woscc/full-record/WOS:000438359500006.
[12] Chen, Chen, Li, Chenlong, Wang, Ying, Renaud, Justin, Tian, Gang, Kambhampati, Shrikaar, Saatian, Behnaz, Vi Nguyen, Hannoufa, Abdelali, Marsolais, Frederic, Yuan, ZeChun, Yu, Kangfu, Austin, Ryan S, Liu, Jun, Kohalmi, Susanne E, Wu, Keqiang, Huang, Shangzhi, Cui, Yuhai. Cytosolic acetyl-CoA promotes histone acetylation predominantly at H3K27 in Arabidopsis. NATURE PLANTS[J]. 2017, 3(10): 814-824,
Research Interests
My group is mainly focused on the regulation of transcription machinery in response to different environmental signals in plants. We integrate multiple strategies such as molecular biology, genetics, epigenetics, high-throughput sequencing, and bioinformatics to reveal the molecular mechanisms of transition from transcription initiation to elongation and the real-time responses of transcription machinery to biotic and abiotic stresses. Take advantage of those fundamental discoveries, we expect to provide potential options for improving the adaptivity and sustainability of crops in adverse environmental conditions.
Students
现指导学生
张志 博士研究生 071010-生物化学与分子生物学
丁宁 博士研究生 071007-遗传学
陈文艺 硕士研究生 071010-生物化学与分子生物学
刘玉娟 博士研究生 071010-生物化学与分子生物学
刘锦源 硕士研究生 086000-生物与医药
王瀛婕 硕士研究生 071007-遗传学