基本信息
罗群 女 硕导 中国科学院化学研究所
电子邮件： qunluo@iccas.ac.cn
通信地址： 北京市海淀区中关村北一街2号中科院化学所
邮政编码： 100190
研究领域
1、多靶点抗肿瘤化合物的设计、合成及其作用机理研究
2、药物相互作用研究新方法，
3、基于多功能分子探针的化学生物学研究
招生信息
接受过化学类、生物类或药学类的本科教育，专业基础扎实、较强的科研能力和创新能力的优秀青年学者。英语基础较好，身心健康，人际交往和谐，具有团队精神。年招生计划1-2人
招生专业
070302-分析化学
招生方向
分析化学
蛋白质组学
化学生物学
蛋白质组学
化学生物学
教育背景
2001-09--2007-02 中国科学院理化技术研究所 博士学位
1988-09--1992-06 湖南师范大学 学士学位
1988-09--1992-06 湖南师范大学 学士学位
学历
博士
学位
博士
工作经历
工作简历
2007-06~现在, 中国科学院化学研究所, 助研/副研
2007-03~2007-06,中国科学院化学研究所, 博士后工作
1992-06~1999-11,空军长沙航空职业技术学院, 讲师
2007-03~2007-06,中国科学院化学研究所, 博士后工作
1992-06~1999-11,空军长沙航空职业技术学院, 讲师
教授课程
分析化学1
专利与奖励
奖励信息
（1） 获得2014年中国分析测试协会科学技术奖( CAIA奖 ), 二等奖, 省级, 2014
专利成果
[1] 汪福意, 侯垠竹, 罗群, 房田田, 甘铁梁, 赵耀, 张燕燕. 吡啶抑素或其衍生物和反式铂类化合物的组合或配合物在制备治疗癌症的药物中的应用. CN: CN115463131A, 2022-12-13.
[2] 罗群, 汪福意, 石慧霞, 唐朝, 孟祥超, 章一鸣, 季安全, 朱军, 王明直, 姜懿璇, 戚鲁豫, 侯垠竹. 鉴定外周血和月经血的应用以及鉴定方法. CN: CN114518414A, 2022-05-20.
[3] 汪福意, 戚鲁豫, 罗群, 赵耀, 张燕燕, 贾菲菲, 房田田. 生物标志物及其应用. CN: CN114262739A, 2022-04-01.
[4] 汪福意, 姜懿璇, 罗群, 赵耀, 张燕燕, 唐朝, 贾菲菲. 一种含5-氨基荧光素类配体的Pt配合物及其制备方法和应用. CN: CN113372393A, 2021-09-10.
[5] 汪福意, 曾文娟, 罗群, 赵耀. 药物损伤DNA功能化磁性纳米亲和探针及其制备方法和应用. CN: CN111812315A, 2020-10-23.
[6] 徐艳, 汪福意, 罗群, 赵耀, 王媛媛, 李向军. 蛋白质功能化磁珠亲和探针及其制备方法与应用. CN: CN110389216B, 2020-07-14.
[7] 徐艳, 汪福意, 罗群, 赵耀, 王媛媛, 李向军. 蛋白质功能化磁珠亲和探针及其制备方法与应用. CN: CN110389216A, 2019-10-29.
[8] 汪福意, 梁祖青, 罗群. 黄酮糖苷功能化磁性纳米亲和探针及其制备方法和应用以及细胞内靶标蛋白捕获方法. CN: CN108693354A, 2018-10-23.
[9] 汪福意, 梁塑, 罗群. 含黄酮类药物活性分子的荧光探针及其制备方法和应用. CN: CN108690033A, 2018-10-23.
[10] 汪福意, 王朝英, 罗群, 吴魁. 一种微流控反应器及其应用以及检测系统和检测液相界面离子分布的方法. CN: CN107345935A, 2017-11-14.
[11] 汪福意, 张扬, 罗群, 赵耀, 郑伟, 张二龙, 吴魁, 王朝英. 含喹唑啉类配体的Pt配合物及其制备方法和应用. CN: CN106188147A, 2016-12-07.
[12] 汪福意, 刘素彦, 吴魁, 罗群, 赵耀. 一种可寻址的样品板及其在单细胞显微成像中的应用. CN: CN106153538A, 2016-11-23.
[13] 汪福意, 杜支凤, 罗群, 郭伟. 一种损伤DNA-纳米金复合物及其制备方法与应用. CN: CN104861037A, 2015-08-26.
[14] 汪福意, 郭伟, 罗群, 李鲜婵. 一种有机金属钌缀合蛋白及其制备方法与应用. CN: CN104072607A, 2014-10-01.
[15] 汪福意, 韩玉苗, 罗群, 郑伟, 吴魁, 李鲜婵. 抑制蛋白酪氨酸磷酸酶1B活性的含钌配合物及其制备方法和蛋白酪氨酸磷酸酶1B抑制剂. CN: CN103360428A, 2013-10-23.
[16] 汪福意, 罗群, 纪丽云, 郑伟, 吕爽. 一种喹唑啉衍生物及其制备方法. CN: CN102452988A, 2012-05-16.
[17] 汪福意, 罗群, 吕爽, 吴魁, 胡文兵, 纪丽云, 韩玉苗. 一种含有钌的配合物及其制备方法. CN: CN101891627A, 2010-11-24.
[18] 汪福意, 罗群, 吕爽, 纪丽云, 胡文兵, 吴魁, 韩玉苗. 一种酪氨酸蛋白激酶抑制剂及其制备方法. CN: CN101890018A, 2010-11-24.
[19] 张燕燕, 汪福意, 罗群. 一种宽温区液体结构的测定方法. CN: CN117309978A, 2023-12-29.
[2] 罗群, 汪福意, 石慧霞, 唐朝, 孟祥超, 章一鸣, 季安全, 朱军, 王明直, 姜懿璇, 戚鲁豫, 侯垠竹. 鉴定外周血和月经血的应用以及鉴定方法. CN: CN114518414A, 2022-05-20.
[3] 汪福意, 戚鲁豫, 罗群, 赵耀, 张燕燕, 贾菲菲, 房田田. 生物标志物及其应用. CN: CN114262739A, 2022-04-01.
[4] 汪福意, 姜懿璇, 罗群, 赵耀, 张燕燕, 唐朝, 贾菲菲. 一种含5-氨基荧光素类配体的Pt配合物及其制备方法和应用. CN: CN113372393A, 2021-09-10.
[5] 汪福意, 曾文娟, 罗群, 赵耀. 药物损伤DNA功能化磁性纳米亲和探针及其制备方法和应用. CN: CN111812315A, 2020-10-23.
[6] 徐艳, 汪福意, 罗群, 赵耀, 王媛媛, 李向军. 蛋白质功能化磁珠亲和探针及其制备方法与应用. CN: CN110389216B, 2020-07-14.
[7] 徐艳, 汪福意, 罗群, 赵耀, 王媛媛, 李向军. 蛋白质功能化磁珠亲和探针及其制备方法与应用. CN: CN110389216A, 2019-10-29.
[8] 汪福意, 梁祖青, 罗群. 黄酮糖苷功能化磁性纳米亲和探针及其制备方法和应用以及细胞内靶标蛋白捕获方法. CN: CN108693354A, 2018-10-23.
[9] 汪福意, 梁塑, 罗群. 含黄酮类药物活性分子的荧光探针及其制备方法和应用. CN: CN108690033A, 2018-10-23.
[10] 汪福意, 王朝英, 罗群, 吴魁. 一种微流控反应器及其应用以及检测系统和检测液相界面离子分布的方法. CN: CN107345935A, 2017-11-14.
[11] 汪福意, 张扬, 罗群, 赵耀, 郑伟, 张二龙, 吴魁, 王朝英. 含喹唑啉类配体的Pt配合物及其制备方法和应用. CN: CN106188147A, 2016-12-07.
[12] 汪福意, 刘素彦, 吴魁, 罗群, 赵耀. 一种可寻址的样品板及其在单细胞显微成像中的应用. CN: CN106153538A, 2016-11-23.
[13] 汪福意, 杜支凤, 罗群, 郭伟. 一种损伤DNA-纳米金复合物及其制备方法与应用. CN: CN104861037A, 2015-08-26.
[14] 汪福意, 郭伟, 罗群, 李鲜婵. 一种有机金属钌缀合蛋白及其制备方法与应用. CN: CN104072607A, 2014-10-01.
[15] 汪福意, 韩玉苗, 罗群, 郑伟, 吴魁, 李鲜婵. 抑制蛋白酪氨酸磷酸酶1B活性的含钌配合物及其制备方法和蛋白酪氨酸磷酸酶1B抑制剂. CN: CN103360428A, 2013-10-23.
[16] 汪福意, 罗群, 纪丽云, 郑伟, 吕爽. 一种喹唑啉衍生物及其制备方法. CN: CN102452988A, 2012-05-16.
[17] 汪福意, 罗群, 吕爽, 吴魁, 胡文兵, 纪丽云, 韩玉苗. 一种含有钌的配合物及其制备方法. CN: CN101891627A, 2010-11-24.
[18] 汪福意, 罗群, 吕爽, 纪丽云, 胡文兵, 吴魁, 韩玉苗. 一种酪氨酸蛋白激酶抑制剂及其制备方法. CN: CN101890018A, 2010-11-24.
[19] 张燕燕, 汪福意, 罗群. 一种宽温区液体结构的测定方法. CN: CN117309978A, 2023-12-29.
出版信息
发表论文
[1] MOLECULES. 2024, 第 10 作者 通讯作者
[2] 唐朝, 罗群. 面向DNA甲基化修饰分析的质谱技术. 化学通报[J]. 2024, 第 2 作者87(1): 27-35, http://lib.cqvip.com/Qikan/Article/Detail?id=7111318887.
[3] Zhou, Yang, Luo, Qun, Zeng, Fangang, Liu, Xingkai, Han, Juanjuan, Gu, Liangzhen, Tian, Xiao, Zhang, Yanyan, Zhao, Yao, Wang, Fuyi. Trichostatin A Promotes Cytotoxicity of Cisplatin, as Evidenced by Enhanced Apoptosis/Cell Death Markers. MOLECULES[J]. 2024, 第 2 作者29(11): http://dx.doi.org/10.3390/molecules29112623.
[4] Tian, Xiao, Gu, Liangzhen, Zeng, Fangang, Liu, Xingkai, Zhou, Yang, Dou, Yang, Han, Juanjuan, Zhao, Yao, Zhang, Yanyan, Luo, Qun, Wang, Fuyi. Strophanthidin Induces Apoptosis of Human Lung Adenocarcinoma Cells by Promoting TRAIL-DR5 Signaling. MOLECULES[J]. 2024, 第 10 作者 通讯作者 29(4): http://dx.doi.org/10.3390/molecules29040877.
[5] Zhu, Li, Liu, Hui, Dou, Yang, Luo, Qun, Gu, Liangzhen, Liu, Xingkai, Zhou, Qianxiong, Han, Juanjuan, Wang, Fuyi. A Photoactivated Ru (II) Polypyridine Complex Induced Oncotic Necrosis of A549 Cells by Activating Oxidative Phosphorylation and Inhibiting DNA Synthesis as Revealed by Quantitative Proteomics. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2023, 第 4 作者 通讯作者 24(9): 7756, http://dx.doi.org/10.3390/ijms24097756.
[6] Zhang, Yanyan, Jin, Jing, Xue, Yifei, Zhao, Yao, Luo, Qun, Mao, Lanqun, Wang, Fuyi. Molecular unravelling of the mechanism of overpotential change at the carbon nanotubes-modified gold electrode surface. CHEMICAL COMMUNICATIONS[J]. 2023, 第 5 作者59(54): 8412-8415, http://dx.doi.org/10.1039/d3cc01818k.
[7] Xingkai Liu, Qian Chen, Xuming Ji, Wanchen Yu, Tong Wang, Juanjuan Han, Shumu Li, Jianan Liu, Fangang Zeng, Yao Zhao, Yanyan Zhang, Qun Luo, Shijun Wang, Fuyi Wang. Astragaloside IV promotes pharmacological effect of Descurainia sophia seeds on isoproterenol-induced cardiomyopathy in rats by synergistically modulating the myosin motor. FRONTIERS IN PHARMACOLOGY[J]. 2022, 第 12 作者 通讯作者 13(null): 939483, https://doaj.org/article/a719a78de5234a28a64f5c2968cdaff2.
[8] Hou, Yinzhu, Liang, Zuqing, Qi, Luyu, Tang, Chao, Liu, Xingkai, Tang, Jilin, Zhao, Yao, Zhang, Yanyan, Fang, Tiantian, Luo, Qun, Wang, Shijun, Wang, Fuyi. Baicalin Targets HSP70/90 to Regulate PKR/PI3K/AKT/eNOS Signaling Pathways. MOLECULES[J]. 2022, 第 10 作者 通讯作者 27(4): http://dx.doi.org/10.3390/molecules27041432.
[9] Hou, Yinzhu, Gan, Tieliang, Fang, Tiantian, Zhao, Yao, Luo, Qun, Liu, Xingkai, Qi, Luyu, Zhang, Yanyan, Jia, Feifei, Han, Juanjuan, Li, Shumu, Wang, Shijun, Wang, Fuyi. G-quadruplex inducer/stabilizer pyridostatin targets SUB1 to promote cytotoxicity of a transplatinum complex. NUCLEIC ACIDS RESEARCH[J]. 2022, 第 5 作者50(6): 3070-3082, http://dx.doi.org/10.1093/nar/gkac151.
[10] Kammer, Lisa Marie, Badir, Shorouk O, Hu, RenMing, Molander, Gary A, Xiaohong Fang. Single cell imaging reveals cisplatin regulating interactions between transcription (co)factors and DNA. CHEMICAL SCIENCE[J]. 2021, 12(15): 5419-5429, http://dx.doi.org/10.1039/d0sc06760a.
[11] 黄超, 梁祖君, 赵耀, 房田田, 吴魁, 罗群, 汪福意. 铂基抗癌药物与蛋白质配位键相互作用质谱研究新进展. 质谱学报[J]. 2021, 第 6 作者42(5): 819-844, https://zpxb.xml-journal.net/article/doi/10.7538/zpxb.2021.0130.
[12] Liang, Su, Wang, Zeyu, Qi, Luyu, Tang, Chao, Zhang, Yiming, Luo, Qun, Wu, Yayun, Yuan, Jinghe, Zhao, Yao, Zhang, Yanyan, Fang, Xiaohong, Wang, Shijun, Wang, Fuyi. Fluorescence live cell imaging revealed wogonin targets mitochondria. TALANTA[J]. 2021, 第 6 作者 通讯作者 230(null): 122328, http://dx.doi.org/10.1016/j.talanta.2021.122328.
[13] Zhao, Yao, Kang, Yan, Xu, Fengmin, Zheng, Wei, Luo, Qun, Zhang, Yanyan, Jia, Feifei, Wang, Fuyi, Sadler, PJ, VanEldik, R. Pharmacophore conjugation strategy for multi-targeting metal-based anticancer complexes. MEDICINAL CHEMISTRY. 2020, 第 5 作者75: 257-285, http://dx.doi.org/10.1016/bs.adioch.2019.10.002.
[14] Li, Chaoyang, Xu, Fengmin, Zhao, Yao, Zheng, Wei, Zeng, Wenjuan, Luo, Qun, Wang, Zhaoying, Wu, Kui, Du, Jun, Wang, Fuyi. Platinum(II) Terpyridine Anticancer Complexes Possessing Multiple Mode of DNA Interaction and EGFR Inhibiting Activity. FRONTIERS IN CHEMISTRY[J]. 2020, 第 6 作者8: https://doaj.org/article/f16506b376664349877e8c6e392ec4f4.
[15] Zhang, Yanyan, Zeng, Wenjuan, Jia, Feifei, Ye, Juan, Zhao, Yao, Luo, Qun, Zhu, Zihua, Wang, Fuyi. Cisplatin-induced alteration on membrane composition of A549 cells revealed by ToF-SIMS. SURFACE AND INTERFACE ANALYSIS[J]. 2020, 第 6 作者52(5): 256-263, https://www.webofscience.com/wos/woscc/full-record/WOS:000494540900001.
[16] Jia, Feifei, Wang, Jie, Zhao, Yao, Zhang, Yanyan, Luo, Qun, Qi, Luyu, Hou, Yinzhu, Du, Jun, Wang, Fuyi. In Situ Visualization of Proteins in Single Cells by Time-of-Flight-Secondary Ion Mass Spectrometry Coupled with Genetically Encoded Chemical Tags. ANALYTICAL CHEMISTRY[J]. 2020, 第 5 作者92(23): 15517-15525, https://www.webofscience.com/wos/woscc/full-record/WOS:000596727600033.
[17] Jia, Feifei, Wu, Kui, Che, Yanli, Zhang, Yanyan, Zeng, Fangang, Luo, Qun, Yu, XiaoYing, Zhu, Zihua, Zhao, Yao, Wang, Fuyi. ToF-SIMS analysis of chemical composition of atmospheric aerosols in Beijing. SURFACE AND INTERFACE ANALYSIS[J]. 2020, 第 6 作者52(5): 272-282, https://www.webofscience.com/wos/woscc/full-record/WOS:000494527400001.
[18] Qi, Luyu, Luo, Qun, Zhang, Yanyan, Jia, Feifei, Zhao, Yao, Wang, Fuyi. Advances in Toxicological Research of the Anticancer Drug Cisplatin. CHEMICAL RESEARCH IN TOXICOLOGY. 2019, 第 2 作者32(8): 1469-1486, https://www.webofscience.com/wos/woscc/full-record/WOS:000482173200003.
[19] Zeng, Wenjuan, Zhang, Yanyan, Zheng, Wei, Luo, Qun, Han, Juanjuan, Liu, Jianan, Zhao, Yao, Jia, Feifei, Wu, Kui, Wang, Fuyi. Discovery of Cisplatin Binding to Thymine and Cytosine on a Single-Stranded Oligodeoxynucleotide by High Resolution FT-ICR Mass Spectrometry. MOLECULES[J]. 2019, 第 4 作者24(10): https://doaj.org/article/4d08fd48b125440da84939bd273a00b7.
[20] Han, Yumiao, Guo, Wei, Zheng, Wei, Luo, Qun, Wu, Kui, Zhao, Yao, Wang, Fuyi. Mass spectrometric quantification of the binding ratio of metal-based anticancer complexes with protein thiols. RAPID COMMUNICATIONS IN MASS SPECTROMETRY[J]. 2019, 第 4 作者33(10): 951-958,
[21] Lin, Yu, Wang, Jie, Zheng, Wei, Luo, Qun, Wu, Kui, Du, Jun, Zhao, Yao, Wang, Fuyi. Organometallic ruthenium anticancer complexes inhibit human peroxiredoxin I activity by binding to and inducing oxidation of its catalytic cysteine residue. METALLOMICS[J]. 2019, 第 4 作者11(3): 546-555, https://www.webofscience.com/wos/woscc/full-record/WOS:000463840800018.
[22] 梁祖青, 罗群, 郑伟, 赵耀, 汪福意. 生物质谱鉴定中药活性成分靶标蛋白质的研究进展. 中国科学：生命科学[J]. 2018, 第 2 作者48(2): 140-150, http://lib.cqvip.com/Qikan/Article/Detail?id=674812393.
[23] Du, Jun, Wei, Yuanyuan, Zhao, Yao, Xu, Fengmin, Wang, Yuanyuan, Zheng, Wei, Luo, Qun, Wang, Ming, Wang, Fuyi. A Photoactive Platinum(IV) Anticancer Complex Inhibits Thioredoxin-Thioredoxin Reductase System Activity by Induced Oxidization of the Protein. INORGANIC CHEMISTRY[J]. 2018, 第 7 作者57(9): 5575-5584, https://www.webofscience.com/wos/woscc/full-record/WOS:000431833500089.
[24] Zhang, Yang, Luo, Qun, Zheng, Wei, Wang, Zhaoying, Lin, Yu, Zhang, Erlong, Lu, Shuang, Xiang, Junfeng, Zhao, Yao, Wang, Fuyi. Luminescent cyclometallated platinum(II) complexes: highly promising EGFR/DNA probes and dual-targeting anticancer agents. INORGANIC CHEMISTRY FRONTIERS[J]. 2018, 第 2 作者5(2): 413-424, https://www.webofscience.com/wos/woscc/full-record/WOS:000425032100016.
[25] Shao ChangFang, Zhao Yao, Wu Kui, Jia FeiFei, Luo Qun, Liu Zhe, Wang FuYi. Correlated Secondary Ion Mass Spectrometry-Laser Scanning Confocal Microscopy Imaging for Single Cell-Principles and Applications. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY. 2018, 第 5 作者46(7): 1005-1016, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=6284555&detailType=1.
[26] Liu, Suyan, Liang, Aihua, Wu, Kui, Zeng, Wenjuan, Luo, Qun, Wang, Fuyi. Binding of Organometallic Ruthenium Anticancer Complexes to DNA: Thermodynamic Base and Sequence Selectivity. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2018, 第 5 作者19(7): https://doaj.org/article/35e1484673a84a00834c1ab1864bbca5.
[27] Shao ChangFang, Zhao Yao, Wu Kui, Jia FeiFei, Luo Qun, Liu Zhe, Wang FuYi. Correlated Secondary Ion Mass Spectrometry-Laser Scanning Confocal Microscopy Imaging for Single Cell-Principles and Applications. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY[J]. 2018, 第 5 作者46(7): 1005-1016, http://dx.doi.org/10.1016/S1872-2040(18)61095-3.
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[19] Zeng, Wenjuan, Zhang, Yanyan, Zheng, Wei, Luo, Qun, Han, Juanjuan, Liu, Jianan, Zhao, Yao, Jia, Feifei, Wu, Kui, Wang, Fuyi. Discovery of Cisplatin Binding to Thymine and Cytosine on a Single-Stranded Oligodeoxynucleotide by High Resolution FT-ICR Mass Spectrometry. MOLECULES[J]. 2019, 第 4 作者24(10): https://doaj.org/article/4d08fd48b125440da84939bd273a00b7.
[20] Han, Yumiao, Guo, Wei, Zheng, Wei, Luo, Qun, Wu, Kui, Zhao, Yao, Wang, Fuyi. Mass spectrometric quantification of the binding ratio of metal-based anticancer complexes with protein thiols. RAPID COMMUNICATIONS IN MASS SPECTROMETRY[J]. 2019, 第 4 作者33(10): 951-958,
[21] Lin, Yu, Wang, Jie, Zheng, Wei, Luo, Qun, Wu, Kui, Du, Jun, Zhao, Yao, Wang, Fuyi. Organometallic ruthenium anticancer complexes inhibit human peroxiredoxin I activity by binding to and inducing oxidation of its catalytic cysteine residue. METALLOMICS[J]. 2019, 第 4 作者11(3): 546-555, https://www.webofscience.com/wos/woscc/full-record/WOS:000463840800018.
[22] 梁祖青, 罗群, 郑伟, 赵耀, 汪福意. 生物质谱鉴定中药活性成分靶标蛋白质的研究进展. 中国科学：生命科学[J]. 2018, 第 2 作者48(2): 140-150, http://lib.cqvip.com/Qikan/Article/Detail?id=674812393.
[23] Du, Jun, Wei, Yuanyuan, Zhao, Yao, Xu, Fengmin, Wang, Yuanyuan, Zheng, Wei, Luo, Qun, Wang, Ming, Wang, Fuyi. A Photoactive Platinum(IV) Anticancer Complex Inhibits Thioredoxin-Thioredoxin Reductase System Activity by Induced Oxidization of the Protein. INORGANIC CHEMISTRY[J]. 2018, 第 7 作者57(9): 5575-5584, https://www.webofscience.com/wos/woscc/full-record/WOS:000431833500089.
[24] Zhang, Yang, Luo, Qun, Zheng, Wei, Wang, Zhaoying, Lin, Yu, Zhang, Erlong, Lu, Shuang, Xiang, Junfeng, Zhao, Yao, Wang, Fuyi. Luminescent cyclometallated platinum(II) complexes: highly promising EGFR/DNA probes and dual-targeting anticancer agents. INORGANIC CHEMISTRY FRONTIERS[J]. 2018, 第 2 作者5(2): 413-424, https://www.webofscience.com/wos/woscc/full-record/WOS:000425032100016.
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科研活动
科研项目
（ 1 ） 微纳米DNA 探针捕获蛋白质-质谱分析联用研究肿瘤细胞对金属抗肿瘤药物的应答机制,, 主持, 国家级, 2013-01--2016-12
（ 2 ） 氢交换质谱研究蛋白质与DNA药物复合物之间的相互作用, 主持, 国家级, 2011-01--2011-12
（ 3 ） 生物活性荧光探针的构建及肿瘤活细胞成像分析研究，, 主持, 市地级, 2012-07--2014-06
（ 4 ） 调控蛋白与药物损伤DNA相互作用研究的分析新方法, 参与, 国家级, 2012-01--2016-12
（ 5 ） 基于利水功效的中药药性理论研究, 参与, 国家级, 2013-01--2017-12
（ 6 ） 中药黄芩活性成分靶标蛋白的捕获与鉴定新方法, 主持, 省级, 2018-01--2019-12
（ 2 ） 氢交换质谱研究蛋白质与DNA药物复合物之间的相互作用, 主持, 国家级, 2011-01--2011-12
（ 3 ） 生物活性荧光探针的构建及肿瘤活细胞成像分析研究，, 主持, 市地级, 2012-07--2014-06
（ 4 ） 调控蛋白与药物损伤DNA相互作用研究的分析新方法, 参与, 国家级, 2012-01--2016-12
（ 5 ） 基于利水功效的中药药性理论研究, 参与, 国家级, 2013-01--2017-12
（ 6 ） 中药黄芩活性成分靶标蛋白的捕获与鉴定新方法, 主持, 省级, 2018-01--2019-12
参与会议
（1）生物活性荧光探针的构建及其在EGFR定量分析中的应用 第八届全国化学生物学学术会议 2013-09-15
（2）生物活性荧光探针的构建及肿瘤活细胞成像分析研究 第十一届全国分析化学年会 2012-10-26
（3）质谱研究碱金属离子对胸苷基T-四联体形成的尺寸效应 第31届中国质谱学会年会 2011-08-06
（2）生物活性荧光探针的构建及肿瘤活细胞成像分析研究 第十一届全国分析化学年会 2012-10-26
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