黄胜雄  男  博导  中国科学院昆明植物研究所
办公电话: 0871-65215112
电子邮件: sxhuang@mail.kib.ac.cn
通信地址: 昆明市蓝黑路132号

邮政编码: 650201

招生信息

   
招生专业
100701-药物化学
100705-微生物与生化药学
070303-有机化学
招生方向
天然药物化学
生物合成,微生物化学
生物合成,合成生物学

教育背景

2004-09--2007-07   中国科学院昆明植物研究所   博士
2001-09--2004-07   中国科学院成都生物研究所   硕士
1997-09--2001-07   陕西师范大学   学士

工作经历

   
工作简历
2013-05~现在, 中国科学院昆明植物研究所, 研究员
2011-01~2013-02,美国斯克利普斯研究所, 研究助理
2008-03~2010-12,威斯康辛大学麦迪逊分校, 研究助理
2007-09~2008-03,香港赛马会中药研究院, 研究员

专利与奖励

   
奖励信息
(1) 青年科技创新领军人才, 国家级, 2017
(2) 五味子化学研究, 特等奖, 省级, 2014
(3) 香茶菜属植物二萜及其抗癌活性研究, 一等奖, 省级, 2013
专利成果
[1] 黄胜雄, 刘阳, 王莉, 周知, 李洁, 罗剑英. 一种吡咯倍半萜类化合物及其制备方法和用途. CN: CN110357864A, 2019-10-22.
[2] 黄胜雄, 纪旭, 颜一军, 杨静, 罗剑英. 一种罗博卢酮的生物合成基因簇及其应用. CN: CN106636141B, 2019-08-13.
[3] 黄胜雄, 纪旭, 颜一军, 杨静, 罗剑英. 一种托酚酮类化合物及其药物组合物和其制备方法与应用. 中国: CN105585573B, 2018-04-17.
[4] 黄胜雄, 汪香婷, 杨静, 杨瑞敏, 张秀磊, 颜一军. α‑吡喃酮类化合物及其药物组合物和其在制药中的应用. 中国: CN107266406A, 2017.10.20.
[5] 普建新, 孙汉董, 肖伟烈, 李蓉涛, 黄胜雄. 抗肿瘤活性的化合物,其制备方法和其应用. 中国: CN101195616, 2008.06.11.
[6] 普建新, 孙汉董, 肖伟烈, 李蓉涛, 黄胜雄. 具有抗肿瘤活性的化合物,其制备方法和其应用. 中国: CN100363367, 2008-01-23.

出版信息

   
发表论文
[1] 邓陈洁, 郭晓为, 黄胜雄, 刘兴勇. 链霉菌Kib015次级代谢产物及其抗菌活性研究. 生物化工. 2023, 9(2): 22-27, http://lib.cqvip.com/Qikan/Article/Detail?id=7109760124.
[2] Zhiyin Yu, Jian-Ping Huang, Jing Yang, Chongxi Liu, Yijun Yan, Li Wang, Junwei Zhao, Yin Chen, Wensheng Xiang, Sheng-Xiong Huang. Discovery and biosynthesis of karnamicins as angiotensin converting enzyme inhibitors. NATURE COMMUNICATIONS[J]. 2023, 14(1): 1-11, http://dx.doi.org/10.1038/s41467-023-35829-1.
[3] Wang, Li, Zhou, Zhi, Huang, JianPing, Zhang, Liang, Tuo, Xiaotao, Yu, Zhiyin, Huang, ShengXiong, Liu, Yang, Yang, Jing. Strepyrrolins A-E, five pyrrole-sesquiterpene hybrids from Streptomyces sp. KIB 015, revealing a new formation logic of pyrroles by isotope labeling. ORGANIC CHEMISTRY FRONTIERS[J]. 2023, 10(4): 880-889, http://dx.doi.org/10.1039/d2qo01767a.
[4] Chen, Yin, Ren, Jinqiu, Yang, Ruimin, Li, Jie, Huang, ShengXiong, Yan, Yijun. Isolation and biosynthesis of daturamycins from Streptomyces sp. KIB-H1544. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY[J]. 2022, 18(1): 1009-1016, http://dx.doi.org/10.3762/bjoc.18.101.
[5] Wang, Zhiyan, Yang, FengXian, Liu, Chongxi, Wang, Li, Qi, Yuxin, Cao, Minghang, Guo, Xiaowei, Li, Jie, Huang, Xueshuang, Yang, Jing, Huang, ShengXiong. Isolation and Biosynthesis of Phenazine-Polyketide Hybrids from Streptomyces sp. KIB-H483. JOURNAL OF NATURAL PRODUCTS[J]. 2022, 85(5): 1324-1331, http://dx.doi.org/10.1021/acs.jnatprod.2c00067.
[6] Wang, YongJiang, Huang, JianPing, Tian, Tian, Yan, Yijun, Chen, Yin, Yang, Jing, Chen, Jianghua, Gu, YuCheng, Huang, ShengXiong. Discovery and Engineering of the Cocaine Biosynthetic Pathway. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2022, 144(48): 22000-22007, http://dx.doi.org/10.1021/jacs.2c09091.
[7] Lv Yulian, Tian Tian, Wang Yongjiang, Huang Jianping, Huang Shengxiong. Advances in chemistry and bioactivity of the genus Erythroxylum. NATURAL PRODUCTS AND BIOPROSPECTING[J]. 2022, 12(3): 1-20, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=7284146&detailType=1.
[8] Tian, Tian, Wang, YongJiang, Huang, JianPing, Li, Jie, Xu, Bingyan, Chen, Yin, Wang, Li, Yang, Jing, Yan, Yijun, Huang, ShengXiong. Catalytic innovation underlies independent recruitment of polyketide synthases in cocaine and hyoscyamine biosynthesis. NATURE COMMUNICATIONS[J]. 2022, 13(1): http://dx.doi.org/10.1038/s41467-022-32776-1.
[9] Yan, Yijun, Yu, Zhiyin, Zhong, Wei, Hou, Xiaodong, Tao, Qiaoqiao, Cao, Minhang, Wang, Li, Cai, Xiaofeng, Rao, Yijian, Huang, ShengXiong. Characterization of Multifunctional and Non-stereoselective Oxidoreductase RubE7/IstO, Expanding the Functional Diversity of the Flavoenzyme Superfamily. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2022, [10] Qiu, Fei, Yan, Yijun, Zeng, Junlan, Huang, JianPing, Zeng, Lingjiang, Zhong, Wei, Lan, Xiaozhong, Chen, Min, Huang, ShengXiong, Liao, Zhihua. Biochemical and Metabolic Insights into Hyoscyamine Dehydrogenase. ACS CATALYSIS[J]. 2021, 11(5): 2912-2924, http://dx.doi.org/10.1021/acscatal.0c04667.
[11] Li, Shanni, Zhong, Wei, Pan, Ying, Lin, Lisha, Cai, Ying, Mao, Hui, Zhang, Taocui, Li, Sujuan, Chen, Ru, Zhou, Lutan, Wang, Weili, Cui, Qinghua, Yin, Ronghua, Huang, Shengxiong, Zhao, Jinhua. Structural characterization and anticoagulant analysis of the novel branched fucosylated glycosaminoglycan from sea cucumber Holothuria nobilis. CARBOHYDRATE POLYMERS[J]. 2021, 269: http://dx.doi.org/10.1016/j.carbpol.2021.118290.
[12] Wang, Li, Yu, Zhiyin, Guo, Xiaowei, Huang, JianPing, Yan, Yijun, Huang, ShengXiong, Yang, Jing. Bisaspochalasins D and E: Two Heterocycle-Fused Cytochalasan Homodimers from an Endophytic Aspergillus flavipes. JOURNAL OF ORGANIC CHEMISTRY[J]. 2021, 86(16): 11198-11205, http://dx.doi.org/10.1021/acs.joc.1c00425.
[13] 余志银, 颜一军, 刘重喜, 黄建萍, 向文胜, 黄胜雄. 稀有放线菌Lechevalieria rhizosphaerae NEAU-A2的次级代谢产物研究及遗传操作系统的建立. 微生物学通报[J]. 2021, 48(7): 2318-2328, http://lib.cqvip.com/Qikan/Article/Detail?id=7105380930.
[14] Yin, Ronghua, Zhou, Lutan, Gao, Na, Lin, Lisha, Sun, Huifang, Chen, Dingyuan, Cai, Ying, Zuo, Zhili, Hu, Kaifeng, Huang, Shengxiong, Liu, Jikai, Zhao, Jinhua. Unveiling the Disaccharide-Branched Glycosaminoglycan and Anticoagulant Potential of Its Derivatives. BIOMACROMOLECULES[J]. 2021, 22(3): 1244-1255, http://dx.doi.org/10.1021/acs.biomac.0c01739.
[15] Huang, JianPing, Wang, YongJiang, Tian, Tian, Wang, Li, Yan, Yijun, Huang, ShengXiong. Tropane alkaloid biosynthesis: a centennial review. NATURAL PRODUCT REPORTS[J]. 2021, 38(9): 1634-1658, http://dx.doi.org/10.1039/d0np00076k.
[16] Yu, Mingming, Luo, Jianying, Luo, Dan, He, Qiang, Yan, Yijun, Ji, Xu, Huang, ShengXiong. Discovery and heterologous production of sarubicins and quinazolinone C-glycosides with protecting activity for cardiomyocytes. ORGANIC CHEMISTRY FRONTIERS[J]. 2021, 8(14): 3829-3837, http://dx.doi.org/10.1039/d1qo00470k.
[17] Han, Chuanyu, Yu, Zhiyin, Zhang, Yuting, Wang, Zhiyan, Zhao, Junwei, Huang, ShengXiong, Ma, Zhonghua, Wen, Ziyue, Liu, Chongxi, Xiang, Wensheng. Discovery of Frenolicin B as Potential Agrochemical Fungicide for Controlling Fusarium Head Blight on Wheat. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2021, 69(7): 2108-2117, http://dx.doi.org/10.1021/acs.jafc.0c04277.
[18] Qiu, Fei, Zeng, Junlan, Wang, Jing, Huang, JianPing, Zhou, Wei, Yang, Chunxian, Lan, Xiaozhong, Chen, Min, Huang, ShengXiong, Kai, Guoyin, Liao, Zhihua. Functional genomics analysis reveals two novel genes required for littorine biosynthesis. NEW PHYTOLOGIST[J]. 2020, 225(5): 1906-1914, http://dx.doi.org/10.1111/nph.16317.
[19] Wang, Li, Yang, Jing, Huang, JianPing, Li, Jie, Luo, Jianying, Yan, Yijun, Huang, ShengXiong. Bisaspochalasins A-C: Three Cytochalasan Homodimers with Highly Fused Ring System from an Endophytic Aspergillus flavipes. ORGANIC LETTERS[J]. 2020, 22(20): 7930-7935, http://dx.doi.org/10.1021/acs.orglett.0c02860.
[20] Yu, Zhiyin, Jiang, Hao, Wang, Li, Yang, FengXian, Huang, JianPing, Liu, Chongxi, Guo, Xiaowei, Xiang, Wensheng, Huang, ShengXiong. Dimeric Pimprinine Alkaloids From Soil-Derived Streptomyces sp. NEAU-C99. FRONTIERS IN CHEMISTRY[J]. 2020, 8: https://doaj.org/article/d206e47582f541f68f4b4ade2e61060e.
[21] Yuan, Jie, Wang, Li, Ren, Jinqiu, Huang, JianPing, Yu, Mingming, Tang, Jun, Yan, Yijun, Yang, Jing, Huang, ShengXiong. Antibacterial Pentacyclic Polyketides from a Soil-Derived Streptomyces. JOURNAL OF NATURAL PRODUCTS[J]. 2020, 83(6): 1919-1924, https://www.webofscience.com/wos/woscc/full-record/WOS:000545691700019.
[22] Wu, Ya, Li, Hao, Yan, Jiao, Cai, Qing, Huang, Shengxiong, Tang, Ying, Ji, Yue, Hao, Xiaojiang, Chen, Gang. Catalyzed Synthesis of 3-hydroxy-indol-2-one Derivatives as a Novel Phosphodiesterases 10 Inhibitor. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY[J]. 2020, 126: 33-34, https://www.webofscience.com/wos/woscc/full-record/WOS:000509492400043.
[23] Ma, Xiaoyan, Zhang, Zhouxin, Wang, Li, Hu, Xinjun, Liu, Xingyong, Huang, ShengXiong. Two New 2(1H)-Pyrazinone Derivatives from the Plant Endophyte Streptomyces sp. KIB-H1992. RECORDS OF NATURAL PRODUCTS[J]. 2020, 14(3): 196-200, http://dx.doi.org/10.25135/rnp.154.1907.1355.
[24] Yu, Zhiyin, Han, Chuanyu, Yu, Bing, Zhao, Junwei, Yan, Yijun, Huang, Shengxiong, Liu, Chongxi, Xiang, Wensheng. Taxonomic Characterization, and Secondary Metabolite Analysis of Streptomyces triticiradicis sp. nov.: A Novel Actinomycete with Antifungal Activity. MICROORGANISMS[J]. 2020, 8(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000514650700082.
[25] Zhuang, Xiaoxin, Wang, Zhiyan, Peng, Chenghui, Su, Can, Gao, Congting, Wang, Yongjiang, Huang, Shengxiong, Liu, Chongxi. Characterization of Streptomyces piniterrae sp. nov. and Identification of the Putative Gene Cluster Encoding the Biosynthesis of Heliquinomycins. MICROORGANISMS[J]. 2020, 8(4): https://www.webofscience.com/wos/woscc/full-record/WOS:000533510400061.
[26] Zhang, Dingli, Hu, Yikao, Wang, Li, Huang, Shengxiong, Zhao, Yan, Li, Mengjia, Li, Feng, Zhao, Yong. Diterpenoids and Sesquiterpenoids from Syzygium fluviatile. RECORDS OF NATURAL PRODUCTS[J]. 2020, 14(3): 190-195, http://dx.doi.org/10.25135/rnp.158.19.08.1393.
[27] Wang YongJiang, Wang Li, He Xin, Xu DongDong, Tang Jun, Ma YaTuan, Yan YiJun, Gu YuCheng, Yang Jing, Huang ShengXiong. Characterization of inthomycin biosynthetic gene cluster revealing new insights into carboxamide formation. CHINESE JOURNAL OF NATURAL MEDICINES[J]. 2020, 18(9): 677-683, http://dx.doi.org/10.1016/S1875-5364(20)60006-1.
[28] Yang, FengXian, Huang, JianPing, Liu, Zhixiang, Wang, Zhiyan, Yang, Jing, Tang, Jun, Yu, Zhiyin, Yan, Yijun, Kai, Guoyin, Huang, ShengXiong. Benwamycins A-G, Trialkyl-Substituted Benzene Derivatives from a Soil-Derived Streptomyces. JOURNAL OF NATURAL PRODUCTS[J]. 2020, 83(1): 111-117, https://www.webofscience.com/wos/woscc/full-record/WOS:000510076700015.
[29] Xu, Min, Zhang, Fei, Cheng, Zhuo, Bashiri, Ghader, Wang, Jing, Hong, Jiali, Wang, Yemin, Xu, Lijun, Chen, Xuefei, Huang, ShengXiong, Lin, Shuangjun, Deng, Zixin, Tao, Meifeng. Functional Genome Mining Reveals a Class V Lanthipeptide Containing ad-Amino Acid Introduced by an F420H2-Dependent Reductase. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2020, 59(41): 18029-18035, https://www.webofscience.com/wos/woscc/full-record/WOS:000561818000001.
[30] Ma, XiaoYan, Huang, JianPing, Yang, Jing, Liu, Xingyong, Hu, Xinjun, Huang, ShengXiong. Concise and efficient syntheses of methyl 4-(1-methylpyrrolidin-2-yl)-3-oxobutanoate and hygrine. CANADIAN JOURNAL OF CHEMISTRY[J]. 2020, 98(4): 191-193, http://dx.doi.org/10.1139/cjc-2019-0442.
[31] Yan, Yijun, Yang, Jing, Wang, Li, Xu, Dongdong, Yu, Zhiyin, Guo, Xiaowei, Horsman, Geoff P, Lin, Shuangjun, Tao, Meifeng, Huang, ShengXiong. Biosynthetic access to the rare antiarose sugar via an unusual reductase-epimerase. CHEMICAL SCIENCE[J]. 2020, 11(15): 3959-3964, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152690/.
[32] Feng, KeNa, Yang, YanLong, Xu, YuXing, Zhang, Yue, Feng, Tao, Huang, ShengXiong, Liu, JiKai, Zeng, Ying. A Hydrolase-Catalyzed Cyclization Forms the Fused Bicyclic beta-Lactone in Vibralactone. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2020, 59(18): 7209-7213, http://dx.doi.org/10.1002/anie.202000710.
[33] Guo, Xiaowei, Wang, Jidong, Su, Can, Liu, Chongxi, Ma, XiaoYan, Yu, Zhiyin, Li, Jiansong, Wang, Xiangjing, Xiang, Wensheng, Huang, ShengXiong. A unique spiro-beta-triazinedione-gamma-hydantoin type alkaloid with antiviral activity against tobacco mosaic virus from Streptomyces gamaensis. ORGANIC CHEMISTRY FRONTIERS[J]. 2019, 6(18): 3215-3219, https://www.webofscience.com/wos/woscc/full-record/WOS:000484960000003.
[34] Wang Lei, Wang Li, Zhou Zhi, Wang YongJiang, Huang JianPing, Ma YaTuan, Liu Yang, Huang ShengXiong. Cangumycins A-F, six new angucyclinone analogues with immunosuppressive activity from Streptomyces. CHINESE JOURNAL OF NATURAL MEDICINES[J]. 2019, 17(12): 982-987, http://lib.cqvip.com/Qikan/Article/Detail?id=7100772594.
[35] Zhang, Zhouxin, Cao, Pei, Shang, NingNing, Yang, Jing, Wang, Li, Yan, Yijun, Huang, ShengXiong. Naphthomycin-derived macrolactams with two new carbon skeletons from endophytic Streptomyces. ORGANIC CHEMISTRY FRONTIERS[J]. 2019, 6(2): 177-182, http://ir.kib.ac.cn/handle/151853/64226.
[36] He, Xin, Wang, Yongjiang, Luo, RongHua, Yang, LiuMeng, Wang, Li, Guo, Dale, Yang, Jing, Deng, Yun, Zheng, YongTang, Huang, ShengXiong. Dimeric Pyranonaphthoquinone Glycosides with Anti-HIV and Cytotoxic Activities from a Soil-Derived Streptomyces. JOURNAL OF NATURAL PRODUCTS[J]. 2019, 82(7): 1813-1819, [37] JianPing Huang, Chengli Fang, Xiaoyan Ma, Li Wang, Jing Yang, Jianying Luo, Yijun Yan, Yu Zhang, ShengXiong Huang. Tropane alkaloids biosynthesis involves an unusual type III polyketide synthase and non-enzymatic condensation. NATURE COMMUNICATIONS[J]. 2019, 10(1): 1-8, http://dx.doi.org/10.1038/s41467-019-11987-z.
[38] Su, Can, Yan, Yijun, Guo, Xiaowei, Luo, Jianying, Liu, Chongxi, Zhang, Zhouxin, Xiang, WenSheng, Huang, ShengXiong. Characterization of the N-methyltransferases involved in the biosynthesis of toxoflavin, fervenulin and reumycin from Streptomyces hiroshimensis ATCC53615. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2019, 17(3): 477-481, https://www.webofscience.com/wos/woscc/full-record/WOS:000458578900007.
[39] Pan, HaiXue, Chen, Zhang, Zeng, Tianfang, Jin, WenBing, Geng, Yujie, Lin, GengMin, Zhao, Juan, Li, WeiTao, Xiong, Zijun, Huang, ShengXiong, Zhai, Xin, Liu, Hungwen, Tang, GongLi. Elucidation of the Herbicidin Tailoring Pathway Offers Insights into Its Structural Diversity. ORGANIC LETTERS[J]. 2019, 21(5): 1374-1378, https://www.webofscience.com/wos/woscc/full-record/WOS:000460491700028.
[40] 黄胜雄. Naphthomycins-Derived Macrolactams with Two New Carbon Skeletons from an Endophytic Streptomyces. Org. Chem. Front.. 2019, [41] 黄胜雄. A unique spiro-β-triazinedione-γ-hydantoin type alkaloid with antiviral activity against tobacco mosaic virus from Streptomyces gamaensis.. Organic Chemistry Frontiers. 2019, [42] Dong, Miao, Cao, Pei, Ma, YaTuan, Luo, Jianying, Yan, Yijun, Li, RongTao, Huang, ShengXiong. A new actinomycin Z analogue with an additional oxygen bridge between chromophore and beta-depsipentapeptide from Streptomyces sp. KIB-H714. NATURAL PRODUCT RESEARCH[J]. 2019, 33(2): 219-225, [43] Liu, Chongxi, Zhuang, Xiaoxin, Yu, Zhiyin, Wang, Zhiyan, Wang, Yongjiang, Guo, Xiaowei, Xiang, Wensheng, Huang, Shengxiong. Community Structures and Antifungal Activity of Root-Associated Endophytic Actinobacteria of Healthy and Diseased Soybean. MICROORGANISMS[J]. 2019, 7(8): https://doaj.org/article/b38629be2fd341349142438f9de921a7.
[44] Su, Can, Liu, Chongxi, Wang, Yongjiang, Xiang, WenSheng, Zou, Chenggang, Huang, ShengXiong. A New Heliquinomycin Analogue with Immunosuppressive Activity from Streptomyces sp. jys28. RECORDS OF NATURAL PRODUCTS[J]. 2019, 13(6): 456-461, [45] Wang, Li, Yan, Yijun, Huang, Jianping, Xiong, Zi-Jun, Yang, Jing, Li, Jie, Huang, Sheng-Xiong, Wang, Zhiyan, Luo, Jianying. Isolation and biosynthesis of labdanmycins: four new labdane diterpenes from endophytic Streptomyces. JOURNAL OF ORGANIC CHEMISTRY[J]. 2018, 83(8): 4867-4870, http://ir.kib.ac.cn/handle/151853/63378.
[46] Yang, FengXian, Hou, GuanXiong, Luo, Jianying, Yang, Jing, Yan, Yijun, Huang, ShengXiong. New phenoxazinone-related alkaloids from strain Streptomyces sp KIB-H1318. JOURNAL OF ANTIBIOTICS[J]. 2018, 71(12): 1040-1043, http://ir.kib.ac.cn/handle/151853/64674.
[47] Shang, NingNing, Zhang, Zhouxin, Huang, JianPing, Wang, Li, Luo, Jianying, Yang, Jing, Peng, Teng, Yan, Yijun, Ma, YaTuan, Huang, ShengXiong. Glycosylated piericidins from an endophytic streptomyces with cytotoxicity and antimicrobial activity. JOURNAL OF ANTIBIOTICS[J]. 2018, 71(7): 672-676, http://ir.kib.ac.cn/handle/151853/64722.
[48] Huang, Sheng-Xiong, Yang, Feng-Xian, Luo, Jianying, Hou, Guan-Xiong, Yang, Jing, Yan, Yijun. New phenoxazinone-related alkaloids from strain Streptomyces sp KIB-H1318. CANCERS[J]. 2018, 10(11): 449-, http://www.irgrid.ac.cn/handle/1471x/1781670.
[49] Yang, Jing, Peng, Teng, Yan, Yijun, Huang, Sheng-Xiong, Ma, Ya-Tuan, Shang, Ning-Ning, Zhang, Zhouxin, Huang, Jian-Ping, Wang, Li, Luo, Jianying. Glycosylated piericidins from an endophytic streptomyces with cytotoxicity and antimicrobial activity. NATURAL PRODUCT COMMUNICATIONS[J]. 2018, 13(7): 795-798, http://ir.kib.ac.cn/handle/151853/63350.
[50] Xiong, ZiJun, Huang, Jianping, Yan, Yijun, Wang, Li, Wang, Zhiyan, Yang, Jing, Luo, Jianying, Li, Jie, Huang, ShengXiong. Isolation and biosynthesis of labdanmycins: four new labdane diterpenes from endophytic Streptomyces. ORGANIC CHEMISTRY FRONTIERS[J]. 2018, 5(8): 1272-1279, http://ir.kib.ac.cn/handle/151853/64747.
[51] Xu, ShaoHua, Xu, Wen, Wang, Li, Hu, YiKao, Liu, JinPing, Zhao, Yan, Li, MengJia, Li, Feng, Huang, ShengXiong, Zhao, Yong. New phloroglucinol derivatives with protein tyrosine phosphatase 1B (PTP1B) inhibitory activities from Syzygium austroyunnanense. FITOTERAPIA[J]. 2018, 131: 141-145, http://ir.kib.ac.cn/handle/151853/64297.
[52] Zhang, Tong, Wang, Li, Duan, DeHua, Zhang, YiHao, Huang, ShengXiong, Chang, Ying. Cytotoxicity-Guided Isolation of Two New Phenolic Derivatives from Dryopteris fragrans (L.) Schott. MOLECULES[J]. 2018, 23(7): https://doaj.org/article/a71a63f0b60849dab2c429857280af36.
[53] Yang RuiMin, Zhang XiuLei, Wang Li, Huang JianPing, Yang Jing, Yan YiJun, Luo JianYing, Wang XiangTing, Huang ShengXiong. α -Pyrone Derivatives from a Streptomyces Strain Resensitize Tamoxifen Resistance in Breast Cancer Cells. NATURAL PRODUCTS AND BIOPROSPECTING[J]. 2017, [54] Wang, Li, Yang, Jing, Kong, LingMei, Deng, Jun, Xiong, Zijun, Huang, Jianping, Luo, Jianping, Yan, Yijun, Hu, Yikao, Li, XiaoNian, Li, Yan, Zhao, Yong, Huang, ShengXiong. Natural and Semisynthetic Tigliane Diterpenoids with New Carbon Skeletons from Euphorbia dracunculoides as a Wnt Signaling Pathway Inhibitor. ORGANIC LETTERS[J]. 2017, 19(14): 3911-3914, https://www.webofscience.com/wos/woscc/full-record/WOS:000406356500057.
[55] Yang, Ruimin, Yang, Jing, Wang, Li, Huang, JianPing, Xiong, Zijun, Luo, Jianying, Yu, Mingming, Yan, Yijun, Huang, ShengXiong. Lorneic Acid Analogues from an Endophytic Actinomycete. JOURNAL OF NATURAL PRODUCTS[J]. 2017, 80(10): 2615-2619, https://www.webofscience.com/wos/woscc/full-record/WOS:000414234400004.
[56] RuiMin Yang, XiuLei Zhang, Li Wang, JianPing Huang, Jing Yang, YiJun Yan, JianYing Luo, XiangTing Wang, ShengXiong Huang. α-Pyrone Derivatives from a Streptomyces Strain Resensitize Tamoxifen Resistance in Breast Cancer Cells. NAT. PROD. BIOPROSPECT.[J]. 2017, 7: 329–334-, http://ir.kib.ac.cn/handle/151853/54995.
[57] 董淼, , 杨凤仙, 罗剑英, 黄胜雄, 马亚团, *, 李蓉涛. 植物内生链霉菌KIB-271抗植物病原真菌活性成分研究. 天然产物研究与开发[J]. 2016, 28(3): 331-334, http://www.trcw.ac.cn/CN/10.16333/j.1001-6880.2016.3.002.
[58] Chi, YuQian, Wang, Li, Ouyang, WenBing, Ma, YaTuan, Yu, MingMing, Zang, Zhen, Zhao, Yan, Huang, ShengXiong, Zhao, Yong. A New Myrinsol Diterpenoid Ester from Euphorbia dracunculoides. CHEMISTRY OF NATURAL COMPOUNDS[J]. 2016, 52(6): 1041-1043, http://ir.kib.ac.cn/handle/151853/33657.
[59] Wang, Li, Ma, YaTuan, Sun, QianYun, Zang, Zhen, Yang, FuMei, Liu, JinPing, Jiang, JinHe, Huang, ShengXiong, Zhao, Yong. A New Lathyrane Diterpenoid Ester from Euphorbia Dracunculoides. CHEMISTRY OF NATURAL COMPOUNDS[J]. 2016, 52(6): 1037-1040, http://ir.kib.ac.cn/handle/151853/33659.
[60] Shi, Min, Zhou, Wei, Zhang, Jianlin, Huang, Shengxiong, Wang, Huizhong, Kai, Guoyin. Methyl jasmonate induction of tanshinone biosynthesis in Salvia miltiorrhiza hairy roots is mediated by JASMONATE ZIM-DOMAIN repressor proteins. SCIENTIFIC REPORTS[J]. 2016, 6(1): http://ir.kib.ac.cn/handle/151853/25955.
[61] Yijun Yan, Jing Yang, Zhiyin Yu, Mingming Yu, YaTuan Ma, Li Wang, Can Su, Jianying Luo, Geoffrey P Horsman, ShengXiong Huang. Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids. NATURE COMMUNICATIONS[J]. 2016, 7(1): http://ir.kib.ac.cn/handle/151853/33643.
[62] Shi, Min, Luo, Xiuqin, Ju, Guanhua, Li, Leilei, Huang, Shengxiong, Zhang, Tong, Wang, Huizhong, Kai, Guoyin. Enhanced Diterpene Tanshinone Accumulation and Bioactivity of Transgenic Salvia miltiorrhiza Hairy Roots by Pathway Engineering. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2016, 64(12): 2523-2530, http://ir.kib.ac.cn/handle/151853/26204.
[63] Xu, Min, Wang, Yemin, Zhao, Zhilong, Gao, Guixi, Huang, ShengXiong, Kang, Qianjin, He, Xinyi, Lin, Shuangjun, Pang, Xiuhua, Deng, Zixin, Tao, Meifeng. Functional Genome Mining for Metabolites Encoded by Large Gene Clusters through Heterologous Expression of a Whole-Genome Bacterial Artificial Chromosome Library in Streptomyces spp.. APPLIED AND ENVIRONMENTAL MICROBIOLOGY[J]. 2016, 82(19): 5795-5805, http://www.irgrid.ac.cn/handle/1471x/1175698.
[64] Yan, Yijun, Ma, YaTuan, Yang, Jing, Horsman, Geoff P, Luo, Dan, Ji, Xu, Huang, ShengXiong. Tropolone Ring Construction in the Biosynthesis of Rubrolone B, a Cationic Tropolone Alkaloid from Endophytic Streptomyces. ORGANIC LETTERS[J]. 2016, 18(6): 1254-1257, http://ir.kib.ac.cn/handle/151853/26179.
[65] Yu, Zhiyin, Wang, Li, Yang, Jing, Zhang, Fan, Sun, Yun, Yu, Mingming, Yan, Yijun, Ma, YaTuan, Huang, ShengXiong. A new antifungal macrolide from Streptomyces sp KIB-H869 and structure revision of halichomycin. TETRAHEDRON LETTERS[J]. 2016, 57(12): 1375-1378, http://dx.doi.org/10.1016/j.tetlet.2016.02.061.
[66] 余志银, , 喻明明, 罗剑英, 苏灿, 薛泉宏, 黄胜雄, 孙芸, 马亚团, *. 青海干旱生境土壤链霉菌次级代谢产物的分离鉴定及活性研究. 天然产物研究与开发[J]. 2015, 27(11): 1900-1904, http://www.trcw.ac.cn/CN/10.16333/j.1001-6880.2015.11.012.
[67] 喻明明, , 苏灿, 马亚团, 颜一军, 黄胜雄, 薛大权. 土壤来源链霉菌KIB-H91次级代谢产物的分离鉴定. 天然产物研究与开发[J]. 2015, 27(6): 1003-1006, http://www.trcw.ac.cn/CN/10.16333/j.1001-6880.2015.06.011.
[68] Wang, Li, Zang, Zhen, Wang, YuFei, Huang, ShengXiong, Cao, Pei, Zhao, Yong. Two new myrinsol diterpenoids from Euphorbia dracunculoides Lam. CHINESE CHEMICAL LETTERS[J]. 2015, 26(1): 121-123, http://dx.doi.org/10.1016/j.cclet.2014.08.005.
[69] Wang, Li, Cao, Pei, Zang, Zhen, Ma, YaTuan, Liu, FengYi, Li, Fei, Wu, XiangHua, Huang, ShengXiong, Zhao, Yong. Two new triterpene rhamnosides from Euphorbia dracunculoides Lam.. PHYTOCHEMISTRY LETTERS[J]. 2015, 12: 168-172, http://dx.doi.org/10.1016/j.phytol.2015.03.015.
[70] Zhang, Ji, Yan, YiJun, An, Jing, Huang, ShengXiong, Wang, XiangJing, Xiang, WenSheng. Designed biosynthesis of 25-methyl and 25-ethyl ivermectin with enhanced insecticidal activity by domain swap of avermectin polyketide synthase. MICROBIAL CELL FACTORIES[J]. 2015, 14(1): http://www.irgrid.ac.cn/handle/1471x/1028961.
[71] Huang, ShengXiong, Yun, BongSik, Ma, Ming, Basu, Hirak S, Church, Dawn R, Ingenhorst, Gudrun, Huang, Yong, Yang, Dong, Lohman, Jeremy R, Tang, GongLi, Ju, Jianhua, Liu, Tao, Wilding, George, Shen, Ben. Leinamycin E1 acting as an anticancer prodrug activated by reactive oxygen species. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2015, 112(27): 8278-8283, https://www.webofscience.com/wos/woscc/full-record/WOS:000357527600051.
[72] Wang, Li, Zang, Zhen, Zhang, Jie, Wu, Xianghua, Huang, Shengxiong, Cao, Pei, Zhao, Yong. A New Premyrsinane-type Diterpenoid Polyester from Euphorbia dracunculoides Lam. RECORDS OF NATURAL PRODUCTS[J]. 2015, 9(3): 374-378, http://www.irgrid.ac.cn/handle/1471x/1028962.
[73] Cao, Pei, Yang, Jing, Miao, CuiPing, Yan, Yijun, Ma, YaTuan, Li, XiaoNian, Zhao, LiXing, Huang, ShengXiong. New Duclauxamide from Penicillium manginii YIM PH30375 and Structure Revision of the Duclauxin Family. ORGANIC LETTERS[J]. 2015, 17(5): 1146-1149, http://www.irgrid.ac.cn/handle/1471x/959041.
[74] Wang, Li, Yang, Jing, Chi, YuQian, Ouyang, WenBin, Zang, Zhen, Huang, ShengXiong, Cao, Pei, Zhao, Yong. A new myrsinol-type diterpene polyester from Euphorbia dracunculoides Lam. NATURAL PRODUCT RESEARCH[J]. 2015, 29(15): 1406-1413, http://www.irgrid.ac.cn/handle/1471x/1000657.
[75] Feng, Chao, Huang, ShengXiong, Gao, XueMei, Xu, HongXi, Luo, Kathy Qian. Characterization of Proapoptotic Compounds from the Bark of Garcinia oblongifolia. JOURNAL OF NATURAL PRODUCTS[J]. 2014, 77(5): 1111-1116, http://www.irgrid.ac.cn/handle/1471x/849563.
[76] Zhang, ZhiJun, Yang, Jing, He, Juan, Wu, XingDe, Shao, LiDong, Li, Yan, Huang, ShengXiong, Li, RongTao, Zhao, QinShi. Vincamajorines A and B, monoterpenoid indole alkaloids with new carbon skeletons from Vinca major. TETRAHEDRON LETTERS[J]. 2014, 55(47): 6490-6494, http://dx.doi.org/10.1016/j.tetlet.2014.10.011.
[77] Zhu, Hucheng, Chen, Chunmei, Yang, Jing, Li, XiaoNian, Liu, Junjun, Sun, Bin, Huang, ShengXiong, Li, Dongyan, Yao, Guangmin, Luo, Zengwei, Li, Yan, Zhang, Jinwen, Xue, Yongbo, Zhang, Yonghui. Bioactive Acylphloroglucinols with Adamantyl Skeleton from Hypericum Sampsonii. ORGANIC LETTERS[J]. 2014, 16(24): 6322-6325, http://www.irgrid.ac.cn/handle/1471x/959036.
[78] Huang Sheng-Xiong, Lohman Jeremy R., Huang Tingting, Shen Ben. A New Member of the 4-Methylideneimidazole-5-one-containing Aminomutase Family from the Enediyne Kedarcidin Biosynthetic Pathway. PROC. NATL. ACAD. SCI. USA[J]. 2013, 8069-8074, http://www.irgrid.ac.cn/handle/1471x/834320.
[79] 杨黎彬, 黄胜雄, 普建新, 李丽梅, 赵勇. 黄花香茶菜二萜化学成分研究. 现代中药研究与实践[J]. 2013, 25-29, http://www.irgrid.ac.cn/handle/1471x/832415.
[80] Huang, ShengXiong, Lohman, Jeremy R, Huang, Tingting, Shen, Ben. A new member of the 4-methylideneimidazole-5-one-containing aminomutase family from the enediyne kedarcidin biosynthetic pathway. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2013, 110(20): 8069-8074, https://www.webofscience.com/wos/woscc/full-record/WOS:000319803500029.
[81] Cheng, JinTang, Liu, Fei, Li, XiaoNian, Wu, XingDe, Dong, LiaoBin, Peng, LiYan, Huang, ShengXiong, He, Juan, Zhao, QinShi. Lycospidine A, a New Type of Lycopodium Alkaloid from Lycopodium complanatum. ORGANIC LETTERS[J]. 2013, 15(10): 2438-2441, https://www.webofscience.com/wos/woscc/full-record/WOS:000319720900029.
[82] 杨黎彬, 黄胜雄, 李丽梅, 赵勇, 普建新. 小叶香茶菜中二萜类化学成分的研究. 华西药学杂志[J]. 2013, 28(3): 234-237, http://www.irgrid.ac.cn/handle/1471x/832438.
[83] 杨黎彬, 黄胜雄, 普建新, 李丽梅, 赵勇. 东亚五味子的木脂素类化学成分研究. 中成药[J]. 2012, 34(12): 2365-2368, https://d.wanfangdata.com.cn/periodical/zhongcy201212025.
[84] Huang, ShengXiong, Feng, Zhiyang, Wang, Liyan, Galm, Ute, WendtPienkowski, Evelyn, Yang, Dong, Tao, Meifeng, Coughlin, Jane M, Duan, Yanwen, Shen, Ben. A Designer Bleomycin with Significantly Improved DNA Cleavage Activity. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2012, 134(32): 13501-13509, https://www.webofscience.com/wos/woscc/full-record/WOS:000307487200055.
[85] Huang Sheng-Xiong, Feng Zhiyang, Wang Liyan, Galm Ute, Wendt-Pienkowski Evelyn, Yang Dong, Tao Meifeng, Coughlin Jane M, Duan Yanwen, Shen Ben. A designer bleomycin with significantly improved DNA cleavage activity. J. AM. CHEM. SOC[J]. 2012, 13501-13509, http://www.irgrid.ac.cn/handle/1471x/834319.
[86] Huang Sheng-Xiong, Wang Xiang-Jing, Yan Yijun, Wang Ji-Dong, Zhang Ji, Liu Cong-Xi, Xiang Wen-Sheng, Shen Ben. Neaumycin - A New Macrolide from Streptomyces sp. NEAU-x211. ORG. LETT[J]. 2012, 1254-1257, http://www.irgrid.ac.cn/handle/1471x/834321.
[87] Liu, JingPing, Zhang, HongBin, Huang, ShengXiong, Pu, JianXin, Xiao, WeiLie, Zhang, XuePing, Xiao, WenDing, Lei, Chun, Sun, HanDong. Synthesis and Biological Evaluation of Laxiflorin J Derivatives as Potential Antitumor Agents. JOURNAL OF HETEROCYCLIC CHEMISTRY[J]. 2012, 49(3): 571-575, http://www.irgrid.ac.cn/handle/1471x/485946.
[88] SternGinossar, Noam, Weisburd, Ben, Michalski, Annette, Vu Thuy Khanh Le, Hein, Marco Y, Huang, ShengXiong, Ma, Ming, Shen, Ben, Qian, ShuBing, Hengel, Hartmut, Mann, Matthias, Ingolia, Nicholas T, Weissman, Jonathan S. Decoding Human Cytomegalovirus. SCIENCE[J]. 2012, 338(6110): 1088-1093, https://www.webofscience.com/wos/woscc/full-record/WOS:000311390600046.
[89] Yang, Libin, Li, Lin, Huang, Shengxiong, Pu, Jianxin, Zhao, Yong, Ma, Yunbao, Chen, Jijun, Leng, Chunhong, Tao, Zhengming, Sun, Handong. Anti-Hepatitis B Virus and Cytotoxic Diterpenoids from Isodon lophanthoides var. gerardianus. CHEMICAL & PHARMACEUTICAL BULLETIN[J]. 2011, 59(9): 1102-1105, https://www.webofscience.com/wos/woscc/full-record/WOS:000294387500005.
[90] Zhou, Yan, Huang, ShengXiong, Pu, JianXin, Li, JinRong, Ding, LiSheng, Chen, DaoFeng, Sun, HanDong, Xu, HongXi. Ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometric procedure for qualitative and quantitative analyses of nortriterpenoids and lignans in the genus Schisandra. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS[J]. 2011, 56(5): 916-927, http://dx.doi.org/10.1016/j.jpba.2011.07.045.
[91] Huang Sheng-Xiong, Powell Emily, Rajski Scott R, Xu Wei, Zhao Li-Xing, Jiang Cheng-Lin, Duan Yanwen, Shen Ben. Discovery and Total Synthesis of a New Estrogen Receptor Heterodimerizing Actinopolymorphol A from Actinopolymorpha rutilus. ORG. LETT[J]. 2010, 3525-3527, http://www.irgrid.ac.cn/handle/1471x/834322.
[92] Lei, Chun, Xiao, WeiLie, Huang, ShengXiong, Chen, JiJun, Pu, JianXin, Sun, HanDong. Pre-schisanartanins C-D and propintrilactones A-B, two classes of new nortriterpenoids from Schisandra propinqua var. propinqua. TETRAHEDRON[J]. 2010, 66(13): 2306-2310, http://dx.doi.org/10.1016/j.tet.2010.02.002.
[93] He, Fei, Pu, JianXin, Huang, ShengXiong, Wang, YuanYuan, Xiao, WeiLie, Li, LiMei, Liu, JingPing, Zhang, HaiBo, Li, Yan, Sun, HanDong. Schinalactone A, a New Cytotoxic Triterpenoid from Schisandra sphenanthera. ORGANIC LETTERS[J]. 2010, 12(6): 1208-1211, http://www.irgrid.ac.cn/handle/1471x/767414.
[94] Huang, ShengXiong, Powell, Emily, Rajski, Scott R, Zhao, LiXing, Jiang, ChengLin, Duan, Yanwen, Xu, Wei, Shen, Ben. Discovery and Total Synthesis of a New Estrogen Receptor Heterodimerizing Actinopolymorphol A from Actinopolymorpha rutilus. ORGANIC LETTERS[J]. 2010, 12(15): 3525-3527, https://www.webofscience.com/wos/woscc/full-record/WOS:000280398900063.
[95] Lei, Chun, Huang, ShengXiong, Xiao, WeiLie, Ma, YunBao, Chen, JiJun, Pu, JianXin, Sun, HanDong. Bisnortriterpenoids Possessing an 18-Nor-schiartane Skeleton from Schisandra propinqua var. propinqua. PLANTA MEDICA[J]. 2010, 76(14): 1611-1615, https://www.webofscience.com/wos/woscc/full-record/WOS:000282366800022.
[96] Lei, Chun, Huang, ShengXiong, Xiao, WeiLie, Ma, YunBao, Chen, JiJun, Pu, JianXin, Sun, HanDong. Bisnortriterpenoids Possessing an 18-Nor-schiartane Skeleton from Schisandra propinqua var. propinqua. PLANTA MEDICA[J]. 2010, 76(14): 1611-1615, https://www.webofscience.com/wos/woscc/full-record/WOS:000282366800022.
[97] Zhao, Yong, Pu, Jian Xin, Huang, Sheng Xiong, Yang, Li Bin, Xiao, Wei Lie, Li, Li Mei, Ding, Li Sheng, Sun, Han Dong. Two new 19-oxygenated ent-kaurane diterpenoids from Isodon pharicus. CHINESE CHEMICAL LETTERS[J]. 2010, 21(1): 81-84, http://dx.doi.org/10.1016/j.cclet.2009.09.009.
[98] Li, XiaoNian, Pu, JianXin, Du, Xue, Lou, LiGuang, Li, LiMei, Huang, ShengXiong, Zhao, Bo, Zhang, Mei, He, Fei, Luo, Xiao, Xiao, WeiLie, Sun, HanDong. Structure and Cytotoxicity of Diterpenoids from Isodon eriocalyx. JOURNAL OF NATURAL PRODUCTS[J]. 2010, 73(11): 1803-1809, http://ir.simm.ac.cn/handle/153631/1949.
[99] Chun Lei, WeiLie Xiao, ShengXiong Huang, JiJun Chen, JianXin Pu, HanDong Sun. Pre-schisanartanins C-D and propintrilactones A-B, two classes of new nortriterpenoids from Schisandra propinqua var. propinqua. TETRAHEDRON[J]. 2010, 66(13): 2306-2310, http://dx.doi.org/10.1016/j.tet.2010.02.002.
[100] Zhou, Yan, Yang, BinLi, Yang, Jing, Huang, ShengXiong, Sun, HanDong, Xu, HongXi, Ding, LiSheng. Electrospray ionization tandem mass spectrometric analysis of ent-6,7-seco-kaurane diterpenoids from the Isodon species. RAPID COMMUNICATIONS IN MASS SPECTROMETRY[J]. 2009, 23(1): 138-146, http://dx.doi.org/10.1002/rcm.3864.
[101] Huang Sheng-Xiong, Feng Chao, Zhou Yan, Xu Gang, Han Quan-Bin, Qiao Chun-Feng, Chang Donald C, Luo Kathy Qian, Xu Hong-Xi. Bioassay-Guided Isolation of Xanthones and Polycyclic Prenylated Acylphloroglucinols from Garcinia oblongifolia. JNATPROD[J]. 2009, 130-135, http://www.irgrid.ac.cn/handle/1471x/834324.
[102] 郁步竹, 宋成芝, 杜芝芝, 蔡祥海, 黄胜雄, 罗晓东. 滑桃树内生真菌Fusarium sp.1RGa—1b中萘醌类代谢产物及其抗菌活性研究. 天然产物研究与开发[J]. 2009, 574-576, http://lib.cqvip.com/Qikan/Article/Detail?id=31494196.
[103] Zhao, Yong, Huang, ShengXiong, Yang, LiBin, Pu, JianXin, Xiao, WeiLie, Li, LiMei, Lei, Chun, Weng, ZhiYing, Han, QuanBin, Sun, HanDong. Cytotoxic ent-Kaurane Diterpenoids from Isodon henryi. PLANTA MEDICA[J]. 2009, 75(1): 65-69, https://www.webofscience.com/wos/woscc/full-record/WOS:000263032200013.
[104] Zhao, Yong, Huang, ShengXiong, Xiao, WeiLie, Ding, LiSheng, Pu, JianXin, Li, Xian, Yang, LiBin, Sun, HanDong. Diterpenoids from Isodon pharicus. TETRAHEDRON LETTERS[J]. 2009, 50(17): 2019-2023, http://dx.doi.org/10.1016/j.tetlet.2009.02.102.
[105] Huang Sheng-Xiong, Zhao Li-Xing, Tang Shu-Kun, Jiang Chen-Lin, Duan Yanwen, Shen Ben. Erythronolides H and I, New Erythromycin Congeners from a New Halophilic Actinomycete Actinopolyspora sp. YIM90600. ORG. LETT[J]. 2009, 1353-1356, http://www.irgrid.ac.cn/handle/1471x/834323.
[106] Lei, Chun, Pu, JianXin, Huang, ShengXiong, Chen, JiJun, Liu, JingPing, Yang, LiBin, Ma, YunBao, Xiao, WeiLie, Li, XiaoNian, Sun, HanDong. A class of 18(13 -> 14)-abeo-schiartane skeleton nortriterpenoids from Schisandra propinqua var. propinqua. TETRAHEDRON[J]. 2009, 65(1): 164-170, http://www.corc.org.cn/handle/1471x/2400824.
[107] Zhao, Yong, Pu, JianXin, Huang, ShengXiong, Wu, YingLi, Yang, LiBin, Xiao, WeiLie, Han, QuanBin, Chen, GuoQiang, Sun, HanDong. ent-Kaurane Diterpenoids from Isodon scoparius. JOURNAL OF NATURAL PRODUCTS[J]. 2009, 72(1): 125-129, https://www.webofscience.com/wos/woscc/full-record/WOS:000262761700023.
[108] Zhao, Yong, Pu, JianXin, Huang, ShengXiong, Ding, LiSheng, Wu, YingLi, Li, Xian, Yang, LiBin, Xiao, WeiLie, Chen, GuoQiang, Sun, HanDong. ent-Kaurane Diterpenoids from Isodon pharicus. JOURNAL OF NATURAL PRODUCTS[J]. 2009, 72(6): 988-993, http://www.irgrid.ac.cn/handle/1471x/256552.
[109] Yang, Jing, Huang, ShengXiong, Zhao, QinShi. Structure Revision of Hassananes with Use of Quantum Mechanical C-13 NMR Chemical Shifts and UV-Vis Absorption Spectra. JOURNAL OF PHYSICAL CHEMISTRY A[J]. 2008, 112(47): 12132-12139, http://dx.doi.org/10.1021/jp8072415.
[110] Pu, JianXin, Yang, LiuMeng, Xiao, WeiLie, Li, RongTao, Lei, Chun, Gao, XueMei, Huang, ShengXiong, Li, ShengHong, Zheng, YongTang, Huang, Hao, Sun, HanDong. Compounds from Kadsura heteroclita and related anti-HIV activity. Phytochemistry[J]. 2008, 69(5): 1266-1272, http://dx.doi.org/10.1016/j.phytochem.2007.11.019.
[111] Huang, ShengXiong, Han, QuanBin, Lei, Chun, Pu, JianXin, Xiao, WeiLie, Yu, JunLin, Yang, LiuMeng, Xu, HongXi, Zheng, YongTang, Sun, HanDong. Isolation and characterization of miscellaneous terpenoids of Schisandra chinensis. TETRAHEDRON[J]. 2008, 64(19): 4260-4267, http://dx.doi.org/10.1016/j.tet.2008.02.085.
[112] Gao, XueMei, Pu, JianXin, Huang, ShengXiong, Lu, Yang, Lou, LiGuang, Li, RongTao, Xiao, WeiLie, Chang, Ying, Sun, HanDong. Kadcoccilactones A-J, triterpenoids from Kadsura coccinea. JOURNAL OF NATURAL PRODUCTS[J]. 2008, 71(7): 1182-1188, http://www.corc.org.cn/handle/1471x/2387827.
[113] Yang Jing, Huang Sheng-Xiong, Zhao Qin-Shi. Structure Revision of Hassananes with use of Quantum Mechanical 13C NMR Chemical Shifts and UV-Vis Absorption Spectra. JPHYCHEMA[J]. 2008, http://www.irgrid.ac.cn/handle/1471x/834325.
[114] Li, Xian, Weng, ZhiYing, Li, Yong, Pu, JianXin, Huang, ShengXiong, Xiao, WeiLie, Sun, HanDong. ent-kaurane diterpenoids from Isodon phyllostachys. HELVETICA CHIMICA ACTA[J]. 2008, 91(6): 1130-1136, https://www.webofscience.com/wos/woscc/full-record/WOS:000257531400017.
[115] Xiao, WeiLie, Huang, ShengXiong, Wang, RuiRui, Zhong, JiaLiang, Gao, XueMei, He, Fei, Pu, JianXin, Lu, Yang, Zheng, YongTang, Zheng, QiTai, Sun, HanDong. Nortriterpenoids and lignans from Schisandra sphenanthera. PHYTOCHEMISTRY[J]. 2008, 69(16): 2862-2866, http://dx.doi.org/10.1016/j.phytochem.2008.09.010.
[116] Yang, LiBin, Yang, Jing, Li, LiMei, Lei, Chun, Zhao, Yong, Huang, ShengXiong, Xiao, WeiLie, Han, QuanBin, Pu, JianXin, Sun, HanDong. Symmetric and asymmetric ent-kaurane dimers isolated from Isodon japonicus. TETRAHEDRON LETTERS[J]. 2008, 49(22): 3574-3577, http://www.corc.org.cn/handle/1471x/2388466.
[117] Lei, Chun, Huang, ShengXiong, Pu, JianXin, Liu, JinPing, Yang, GuangYu, Yang, LiBin, Lu, Yang, Chen, JiJun, Lu, Yang, Xiao, WeiLie, Sun, HanDong. Lanopropic acid, a novel natural 2,3-secolanostane triterpenoid form schisandra propinua var. propinqua. PLANTA MEDICA[J]. 2008, 74(3): 292-295, http://www.corc.org.cn/handle/1471x/2389416.
[118] Gao, XueMei, Pu, JianXin, Huang, ShengXiong, Yang, LiuMeng, Huang, Hao, Xiao, WeiLie, Zheng, YongTang, Sun, HanDong. Lignans from Kadsura angustifolia. JOURNAL OF NATURAL PRODUCTS[J]. 2008, 71(4): 558-563, http://dx.doi.org/10.1021/np0705108.
[119] Lei, Chun, Huang, ShengXiong, Chen, Jijun, Yang, LiBin, Xiao, WeiLie, Chang, Yin, Lu, Yang, Huang, Hao, Pu, JianXin, Sun, HanDong. Propindilactones E-J, schiartane nortriterpenoids from Schisandra propinqua var. propinqua. JOURNAL OF NATURAL PRODUCTS[J]. 2008, 71(7): 1228-1232, http://www.corc.org.cn/handle/1471x/2386375.
[120] Pu, JianXin, Gao, XueMei, Lei, Chun, Xiao, WeiLie, Wang, RuiRui, Yang, LiBin, Zhao, Yong, Li, LiMei, Huang, ShengXiong, Zheng, YongTang, Sun, HanDong. Three new compounds from Kadsura longipedunculata. CHEMICAL & PHARMACEUTICAL BULLETIN[J]. 2008, 56(8): 1143-1146, http://159.226.149.42:8080:8088/handle/152453/4625.
[121] Gao, XueMei, Pu, JianXin, Xiao, WeiLie, Huang, ShengXiong, Lou, LiGuang, Sun, HanDong. Kadcoccilactones K-R, triterpenoids from Kadsura coccinea. TETRAHEDRON[J]. 2008, 64(51): 11673-11679, http://dx.doi.org/10.1016/j.tet.2008.10.011.
[122] He, Fei, Pu, JianXin, Huang, ShengXiong, Xiao, WeiLie, Yang, LiBin, Li, XiaoNian, Zhao, Yong, Ding, Jian, Xu, ChengHui, Sun, HanDong. Eight New Diterpenoids from the Roots of Euphorbia nematoopha. HELVETICA CHIMICA ACTA[J]. 2008, 91(11): 2139-2147, http://www.corc.org.cn/handle/1471x/2388898.
[123] Zhou, Yan, Huang, ShengXiong, Li, LiMei, Yang, Jing, Liu, Xin, Peng, ShuLin, Ding, LiSheng, Sun, HanDong. Negative electrospray ionization tandem mass spectrometric investigation of ent-kaurane diterpenoids from the genus Isodon. JOURNAL OF MASS SPECTROMETRY[J]. 2008, 43(1): 63-73, http://www.irgrid.ac.cn/handle/1471x/256487.
[124] Zhao, Yong, Bin Yang, Li, Huang, Sheng Xiong, Xiao, Wei Lie, Pu, Jian Xin, Li, Mei Li, Bin Han, Quan, Sun, Han Dong. Two new ent-kaurane diterpenoids from Isodon henryi. CHINESE CHEMICAL LETTERS[J]. 2008, 19(9): 1096-1098, http://lib.cqvip.com/Qikan/Article/Detail?id=28210168.
[125] Lei, Chun, Huang, ShengXiong, Chen, JiJun, Pu, JianXin, Li, LiMei, Xiao, WeiLie, Liu, JinPing, Yang, LiBin, Sun, HanDong. Four new schisanartane-type nortriterpenoids from Schisandra propinqua var. propinqua. HELVETICA CHIMICA ACTA[J]. 2007, 90(7): 1399-1405, http://www.corc.org.cn/handle/1471x/2381852.
[126] 翁稚颖, 黄胜雄, 韩全斌, 肖伟烈, 孙汉董. Xerophinoid C,旱生香茶菜中一个新的二萜糖苷化合物. 云南植物研究[J]. 2007, 29(2): 256-258, http://lib.cqvip.com/Qikan/Article/Detail?id=24460701.
[127] Huang, ShengXiong, Zhou, Yan, Yang, LiBin, Zhao, Yong, Li, ShengHong, Lou, LiGuang, Han, QuanBin, Ding, LiSheng, Sun, HanDong. Alboatisins A-C, ent-atisene diterpenoids from Isodon albopilosus. JOURNAL OF NATURAL PRODUCTS[J]. 2007, 70(6): 1053-1055, http://210.75.237.14/handle/351003/26763.
[128] Xiao, WeiLie, Pu, JianXin, Wang, RuiRui, Yang, LiuMeng, Li, XiaoLi, Li, ShengHong, Li, RongTao, Huang, ShengXiong, Zheng, YongTang, Sun, HanDong. Isolation and structure elucidation of nortriterpenoids from Schisandra rubriflora. Helvetica Chimica Acta[J]. 2007, 90(8): 1505-1513, http://www.irgrid.ac.cn/handle/1471x/1151225.
[129] Li, LiMei, Li, GuoYou, Ding, LiSheng, Lei, Chun, Yang, LiBin, Zhao, Yong, Weng, ZhiYing, Li, ShengHing, Huang, ShengXiong, Xiao, WeiLie, Han, QuanBin, Sun, HanDong. Sculponins A-C, three new 6,7-seco-ent-kauranoids from Isodon sculponeatus. TETRAHEDRON LETTERS[J]. 2007, 48(52): 9100-9103, http://dx.doi.org/10.1016/j.tetlet.2007.10.133.
[130] Huang, ShengXiong, Yang, Jing, Huang, Hao, Li, LiMei, Xiao, WeiLie, Li, RongTao, Sun, HanDong. Structural characterization of schintrilactone, a new class of nortriterpenoids from Schisandra chinensis. ORGANIC LETTERS[J]. 2007, 9(21): 4175-4178, https://www.webofscience.com/wos/woscc/full-record/WOS:000249987200023.
[131] Yang, LiBin, Huang, ShengXiong, Li, LiMei, Zhao, Yong, Lei, Chun, Xiao, WeiLie, Pu, JianXin, Han, QuanBin, Sun, HanDong. ent-Kaurane diterpenoids from Isodon japonicus. HELVETICA CHIMICA ACTA[J]. 2007, 90(12): 2375-2379, http://www.corc.org.cn/handle/1471x/2382503.
[132] Pu, JianXin, Huang, ShengXiong, Ren, Jie, Xiao, WeiLie, Li, LiMei, Li, RongTao, Li, LiangBo, Liao, TouGen, Lou, LiGuang, Zhu, HuaJie, Sun, HanDong. Isolation and structure elucidation of kadlongilactones C-F from kadsura longipedunculata by NMR spectroscopy and DFT computational methods. JOURNAL OF NATURAL PRODUCTS[J]. 2007, 70(11): 1706-1711, http://ir.simm.ac.cn/handle/153631/1672.
[133] Huang, ShengXiong, Li, RongTao, Liu, JingPing, Lu, Yang, Chang, Ying, Lei, Chun, Xiao, WeiLie, Yang, LiBin, Zheng, QiTai, Sun, HanDong. Isolation and characterization of biogenetically related highly oxygenated nortriterpenoids from Schisandra chinensis. ORGANIC LETTERS[J]. 2007, 9(11): 2079-2082, https://www.webofscience.com/wos/woscc/full-record/WOS:000246569900008.
[134] Huang, ShengXiong, Pu, JianXin, Xiao, WeiLie, Li, LiMei, Weng, ZhiYing, Zhou, Yan, Han, QuanBin, Peng, ShuLin, Ding, LiSheng, Lou, LiGuang, Sun, HanDong. ent-Abietane diterpenoids from Isodon rubescens var. rubescens. PHYTOCHEMISTRY[J]. 2007, 68(5): 616-622, http://dx.doi.org/10.1016/j.phytochem.2006.11.007.
[135] 孙汉董. Wuweizidilactones A-F: Novel highly oxygenated nortriterpenoids with unusual skeletons isolated from schisandra chinensis. CHEM EUR J[J]. 2007, 13(13): 4816-4822, http://ir.kib.ac.cn/handle/151853/18025.
[136] Xiao, WeiLie, Yang, LiuMeng, Li, LiMei, Pu, JianXin, Huang, ShengXiong, Weng, ZhiYing, Lei, Chun, Liu, JingPing, Wang, RuiRui, Zheng, YongTang, Li, RongTao, Sun, HanDong. Sphenalactones A-D, a new class of highly oxygenated trinortriterpenoids from Schisandra sphenanthera. TETRAHEDRON LETTERS[J]. 2007, 48(31): 5543-5546, http://dx.doi.org/10.1016/j.tetlet.2007.05.152.
[137] Pu, JianXin, Li, RongTao, Xiao, WeiLie, Gong, NingBo, Huang, ShengXiong, Lu, Yang, Zheng, QiTai, Lou, LiGuang, Sun, HanDong. Longipedlactones A-I, nine novel triterpene dilactones possessing a unique skeleton from Kadsura longipedunculata. TETRAHEDRON[J]. 2006, 62(25): 6073-6081, http://dx.doi.org/10.1016/j.tet.2006.03.108.
[138] Sun, HanDong, Huang, ShengXiong, Han, QuanBin. Diterpenoids from Isodon species and their biological activities. NATURAL PRODUCT REPORTSnull. 2006, 23(5): 673-698, https://www.webofscience.com/wos/woscc/full-record/WOS:000240816200002.
[139] Li, LiMei, Li, GuoYou, Xiao, WeiLie, Zhou, Yan, Li, ShengHong, Huang, ShengXiong, Han, QuanBin, Ding, LiSheng, Lou, LiGuang, Sun, HanDong. A new rearranged and a new seco-ent-kaurane diterpenoids from Isodon parvifolius. TETRAHEDRON LETTERS[J]. 2006, 47(29): 5187-5190, http://dx.doi.org/10.1016/j.tetlet.2006.05.025.
[140] Li, Mei Li, Huang, ShengXiong, Peng, LiYan, Li, GuoYou, Xiao, WeiLie, Zhou, Yan, Han, QuanBin, Ding, LiSheng, Sun, HanDong. Ent-abietane and ent-labdane diterpenoids from Isodon parvifolius. CHEMICAL & PHARMACEUTICAL BULLETIN[J]. 2006, 54(7): 1050-1052, http://www.irgrid.ac.cn/handle/1471x/256330.
[141] 赵勤实, 孙汉董, 杨郁, 黄胜雄, 赵毅民. 花石蒜中的黄酮类成分. 天然产物研究与开发[J]. 2005, 17(5): 539-541, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=2134299&detailType=1.
发表著作
(1) 二萜化学, 二萜化学, 化学工业出版社, 2012-04, 第 3 作者

科研活动

   
科研项目
( 1 ) 托酚酮类天然产物rubrolone 的生物合成研究, 主持, 国家级, 2014-01--2017-12
( 2 ) 青年****基金, 主持, 国家级, 2015-11--2018-10
( 3 ) 云南省高端科技人才计划, 主持, 省级, 2014-01--2018-12
( 4 ) 天然药物化学, 主持, 国家级, 2016-01--2018-12
( 5 ) 云南特色内生菌资源中生物碱类先导化 合物的发现与生物合成, 主持, 国家级, 2018-01--2021-12

指导学生

已指导学生

杨瑞敏  硕士研究生  078001-药物化学  

熊子君  博士研究生  071010-生物化学与分子生物学  

现指导学生

王莉  博士研究生  100701-药物化学  

苏灿  博士研究生  071010-生物化学与分子生物学  

喻明明  博士研究生  100701-药物化学  

任金秋  硕士研究生  078001-药物化学  

徐冬冬  博士研究生  100701-药物化学  

杨凤仙  博士研究生  100701-药物化学  

徐冰艳  硕士研究生  078001-药物化学  

唐俊  博士研究生  100701-药物化学  

王志岩  博士研究生  100701-药物化学