071010-生物化学与分子生物学
071005-微生物学

单细胞拉曼光谱，高通量筛选，合成生物学，单细胞分析

2014-07--2017-12   中国科学院青岛生物能源与过程研究所   理学博士
2011-09--2014-06   中国科学院青岛生物能源与过程研究所   工学硕士
2007-09--2011-06   西北农林科技大学   工学学士

   

2023-01~现在, 中国科学院青岛生物能源与过程研究所, 副研究员
2020-11~2022-12,中国科学院青岛生物能源与过程研究所, 助理研究员
2018-01~2020-10,中国科学院青岛生物能源与过程研究所, 博士后

   

[1] 何曰辉, 籍月彤, 徐健. 一种含色素细胞样品的非色素拉曼信号采集的方法. CN: CN112557370A, 2021-03-26.
[2] 籍月彤, 王婷婷, 王允, 何曰辉, 黄巍, 徐健. 一种快速检测微藻产能过程的方法. CN: CN103592283A, 2014-02-19.

   

[1] Wang, Xixian, Ren, Lihui, Diao, Zhidian, He, Yuehui, Zhang, Jiaping, Liu, Min, Li, Yuandong, Sun, Lijun, Chen, Rongze, Ji, Yuetong, Xu, Jian, Ma, Bo. Robust Spontaneous Raman Flow Cytometry for Single-Cell Metabolic Phenome Profiling via pDEP-DLD-RFC. ADVANCED SCIENCE[J]. 2023, 10(16): http://dx.doi.org/10.1002/advs.202207497.
[2] Wang, Xiufen, He, Yuehui, Zhou, Yuanyuan, Zhu, Baohua, Xu, Jian, Pan, Kehou, Li, Yun. An attempt to simultaneously quantify the polysaccharide, total lipid, protein and pigment in single Cyclotella cryptica cell by Raman spectroscopy. BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS[J]. 2023, 16(1): 1-19, https://doaj.org/article/72f9d1da8c2d40039b6569cbc42c60a8.
[3] Zhu, Pengfei, Ren, Lihui, Zhu, Ying, Dai, Jing, Liu, Huijie, Mao, Yuli, Li, Yuandong, He, Yuehui, Zheng, Xiaoshan, Chen, Rongze, Fu, Xiaoting, Zhang, Lili, Sun, Lijun, Zhu, Yuanqi, Ji, Yuetong, Ma, Bo, Xu, Yingchun, Xu, Jian, Yang, Qiwen. Rapid, automated, and reliable antimicrobial susceptibility test from positive blood culture by CAST‐R. mLife[J]. 2022, 1(3): 329-340, https://doaj.org/article/912367288e26459dbd8f8bdd005d8d4c.
[4] Zhang, Peng, Xin, Yi, He, Yuehui, Tang, Xianfeng, Shen, Chen, Wang, Qintao, Lv, Nana, Li, Yun, Hu, Qiang, Xu, Jian. Exploring a blue-light-sensing transcription factor to double the peak productivity of oil in Nannochloropsis oceanica. NATURE COMMUNICATIONS[J]. 2022, 13(1): https://doaj.org/article/9b1182144e664757992bd54ebc491022.
[5] He, Yuehui, Huang, Shi, Zhang, Peng, Ji, Yuetong, Xu, Jian. Intra-Ramanome Correlation Analysis Unveils Metabolite Conversion Network from an Isogenic Population of Cells. MBIO[J]. 2021, 12(4): http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000694734900003.
[6] Wang, Qintao, Gong, Yanhai, He, Yuehui, Xin, Yi, Lv, Nana, Du, Xuefeng, Li, Yun, Jeong, ByeongRyool, Xu, Jian. Genome engineering of Nannochloropsis with hundred-kilobase fragment deletions by Cas9 cleavages. PLANT JOURNAL[J]. 2021, 106(4): 1148-1162, http://dx.doi.org/10.1111/tpj.15227.
[7] Baladehi, Mohammadhadi Heidari, Hekmatara, Maryam, He, Yuehui, Bhaskar, Yogendra, Wang, Zengbin, Liu, Lu, Ji, Yuetong, Xu, Jian. Culture-Free Identification and Metabolic Profiling of Microalgal Single Cells via Ensemble Learning of Ramanomes. ANALYTICAL CHEMISTRY[J]. 2021, 93(25): 8872-8880, http://dx.doi.org/10.1021/acs.analchem.1c01015.
[8] He, Yuehui, Wang, Xixian, Ma, Bo, Xu, Jian. Ramanome technology platform for label-free screening and sorting of microbial cell factories at single-cell resolution. BIOTECHNOLOGY ADVANCESnull. 2019, 37(6): http://dx.doi.org/10.1016/j.biotechadv.2019.04.010.
[9] He, Yuehui, Zhang, Peng, Huang, Shi, Wang, Tingting, Ji, Yuetong, Xu, Jian. Label-free, simultaneous quantification of starch, protein and triacylglycerol in single microalgal cells. BIOTECHNOLOGY FOR BIOFUELS[J]. 2017, 10(1): http://www.irgrid.ac.cn/handle/1471x/1755760.
[10] Ji, Yuetong, He, Yuehui, Cui, Yanbin, Wang, Tingting, Wang, Yun, Li, Yuanguang, Huang, Wei E, Xu, Jian. Raman spectroscopy provides a rapid, non-invasive method for quantitation of starch in live, unicellular microalgae. BIOTECHNOLOGY JOURNAL[J]. 2014, 9(12): 1512-1518, http://dx.doi.org/10.1002/biot.201400165.

   

（ 1 ） 服务微生物细胞工厂高效筛选的“基因组-泛拉曼组”数据类型构建及应用示范, 负责人, 国家任务, 2023-01--2026-12
（ 2 ） 多重稳定同位素标记结合单细胞拉曼光谱技术筛选微藻突变体方法学研究, 负责人, 国家任务, 2020-01--2022-12
（ 3 ） 单细胞拉曼光谱筛选高固碳效率微藻突变体方法学研究, 负责人, 其他国际合作项目, 2019-01--2020-01
（ 4 ） 重水标记结合单细胞拉曼光谱技术筛选微藻突变体方法学研究, 负责人, 地方任务, 2019-07--2022-06
（ 5 ） 单细胞精度的菌群“代谢表型组-基因组”方法学研究, 参与, 国家任务, 2021-01--2025-12
（ 6 ） 聚阳离子多肽（Silaffins）在小环藻硅壳合成中的 功能机制, 参与, 国家任务, 2020-01--2023-12
（ 7 ） 基于单细胞拉曼光谱的高通量表型检测与分选方法 学研究, 参与, 国家任务, 2020-01--2023-12
（ 8 ） 基于宏基因组大数据搜索的微生物组疾病检测方法学研究, 参与, 国家任务, 2021-01--2024-12