基本信息
尹恒  男  博导  中国科学院大连化学物理研究所
电子邮件: yinheng@dicp.ac.cn
通信地址: 辽宁省大连市中山路457号
邮政编码: 116023

研究领域

​糖工程与酶工程,植物糖生物学与植物免疫

招生信息

招生专业
081703-生物化工
招生方向
糖工程与酶工程
植物免疫与植物糖生物学

教育背景

2004-12--2006-08   复旦大学上海医学院   合作培养,攻读博士学位
2003-09--2008-08   中国科学院大连化学物理研究所   博士
1999-09--2003-06   大连理工大学   学士
学历

博士研究生

学位

博士

工作经历

工作简历
2015-07~2017-10,中国科学院大连化学物理研究所, 研究员
2011-10~2015-07,中国科学院大连化学物理研究所, 副研究员
2010-03~2011-02,丹麦奥胡斯大学, 访问学者
2008-10~2011-10,中国科学院大连化学物理研究所, 助理研究员
社会兼职
2020-01-01-今,生物农药与生物防治产业技术创新战略联盟, 副理事长
2018-07-01-今,大连市糖类农用制剂工程研究中心, 主任
2017-10-20-今,中国生物防治学报, 编委
2017-10-11-今,中国植物保护学会生物防治专业委员会, 委员
2017-08-31-今,中国生物工程学会糖生物工程专委会委员, 委员
2017-01-10-今,全国农药标委会生物农药分委会委员, 委员
2016-08-07-今,中国生化与分子生物学会糖复合物专委会委员,
2014-11-16-今,中科院青年创新促进会会员,
2014-07-01-今,国际植物与微生物间分子互作学会, 委员
2014-06-07-今,辽宁省碳水化合物研究重点实验室主任, 主任

专利与奖励

奖励信息
(1) 辽宁省“百千万人才工程”百层次, 省级, 2020
(2) 张大煜优秀学者, 研究所(学校), 2019
(3) 中国科学院青年创新促进会优秀会员, 院级, 2019
(4) 辽宁省兴辽英才“兴辽英才计划”青年拔尖人才, 省级, 2019
(5) 沈阳分院优秀青年科技人才奖, 院级, 2016
(6) 张树政糖科学优秀青年奖, 其他, 2015
(7) 大连市杰出青年科技人才, 市地级, 2015
(8) 中科院大连化物所科技冠名奖青年优秀奖, 研究所(学校), 2015
(9) 辽宁省科技进步奖二等奖, 二等奖, 省级, 2014
(10) 海洋科学技术奖, 一等奖, 部委级, 2013
(11) 辽宁省自然科学学术成果奖, 三等奖, 省级, 2011
(12) 大连化物所康宁(DICP-Corning)奖, 一等奖, 研究所(学校), 2008
(13) 辽宁省自然科学学术成果奖, 三等奖, 省级, 2007
专利成果
( 1 ) 一种内切β-1,4-甘露聚糖酶编码基因及其制备与应用, 专利授权, 2021, 第 1 作者, 专利号: CN108611356B

( 2 ) 一种含海藻酸寡糖与新奥苷肽杀菌复配剂及其应用, 发明专利, 2021, 第 3 作者, 专利号: CN112868656A

( 3 ) 磷酸果糖氨基转移酶编码基因及酶的制备与应用, 发明专利, 2021, 第 1 作者, 专利号: CN112852774A

( 4 ) 一种海藻酸钠低聚糖聚合度检测方法, 发明专利, 2021, 第 1 作者, 专利号: CN112683888A

( 5 ) 5-羟甲基糠醛氧化酶基因HMFO及其编码酶和应用, 专利授权, 2021, 第 1 作者, 专利号: CN108118064B

( 6 ) 一种农作物日灼病防治剂及其应用, 专利授权, 2021, 第 2 作者, 专利号: CN109892330B

( 7 ) 一种几丁二糖的生产方法, 专利授权, 2021, 第 3 作者, 专利号: CN106834386B

( 8 ) 一种添加寡糖的复合冲施肥料及其制备方法, 发明专利, 2021, 第 1 作者, 专利号: CN112390675A

( 9 ) 一种具有ROS响应的农药缓释制剂及其制备与应用, 发明专利, 2021, 第 1 作者, 专利号: CN112237184A

( 10 ) 一种含寡糖的花期延长剂及其应用, 专利授权, 2020, 第 1 作者, 专利号: CN108056109B

( 11 ) 一种甘露糖醛酸C-5差向异构酶/海藻酸裂解酶编码基因及酶和制备与应用, 发明专利, 2020, 第 1 作者, 专利号: CN111849949A

( 12 ) 一种HMFO@MOFs复合物材料及其制备方法和应用, 发明专利, 2020, 第 1 作者, 专利号: CN111849954A

( 13 ) 一种葡寡糖复配制剂及其在马铃薯病害防治中的应用, 专利授权, 2020, 第 1 作者, 专利号: CN108056103B

( 14 ) 一种蔬果保鲜方法, 发明专利, 2020, 第 1 作者, 专利号: CN111657342A

( 15 ) 乙酰葡萄糖胺磷酸变位酶AtAGM编码基因及其酶、制备、应用与酶活性检测方法, 专利授权, 2020, 第 1 作者, 专利号: CN106755022B

( 16 ) 一种酪氨酸酶前体与编码基因及其制备与应用, 发明专利, 2020, 第 1 作者, 专利号: CN111218432A

( 17 ) 一株亚麻籽胶降解菌及其筛选和应用, 发明专利, 2020, 第 1 作者, 专利号: CN111218411A

( 18 ) 重组鹰嘴豆孢克鲁维酵母CBS4857外切菊粉酶及编码基因与表达和应用, 专利授权, 2020, 第 1 作者, 专利号: CN106554951B

( 19 ) 几丁质脱乙酰酶和编码基因及应用, 发明专利, 2020, 第 1 作者, 专利号: CN111154745A

( 20 ) 氧化水解酶基因BtLPMO10B及氧化水解酶与应用, 专利授权, 2020, 第 2 作者, 专利号: CN105713913B

( 21 ) 一种酶法制备2,5-呋喃二甲酸的方法, 专利授权, 2020, 第 2 作者, 专利号: CN106554978B

( 22 ) 一种重组黄曲霉壳聚糖酶和编码基因及制备和应用, 专利授权, 2020, 第 1 作者, 专利号: CN107418941B

( 23 ) 一种液态花生粕有机肥及其制备方法和应用, 发明专利, 2020, 第 1 作者, 专利号: CN110818459A

( 24 ) 氧化水解酶基因BtLPMO10A及氧化水解酶与应用, 专利授权, 2020, 第 2 作者, 专利号: CN105713912B

( 25 ) 一种高产窄分布果胶寡糖的黑曲霉和果胶酶及其应用, 发明专利, 2020, 第 1 作者, 专利号: CN110713935A

( 26 ) 一种褐藻胶裂解酶Algb及其编码基因和应用, 专利授权, 2020, 第 1 作者, 专利号: CN105624137B

( 27 ) 一种β-1,4-葡聚糖酶编码基因及其制备与应用, 专利授权, 2020, 第 1 作者, 专利号: CN108611340B

( 28 ) 一种硒化魔芋葡甘寡糖及其制备和应用, 发明专利, 2019, 第 1 作者, 专利号: CN110526996A

( 29 ) 一种含有海藻酸钠寡糖的植物伤口愈合剂及其用途, 专利授权, 2019, 第 1 作者, 专利号: CN106804605B

( 30 ) 一种壳聚糖包覆嘧菌酯纳米微球及其制备方法, 发明专利, 2019, 第 1 作者, 专利号: CN109953020A

( 31 ) 一种多糖裂解单加氧酶编码基因及酶和制备与应用, 发明专利, 2019, 第 1 作者, 专利号: CN109957571A

( 32 ) 一种壳聚糖纳米颗粒的制备方法, 发明专利, 2019, 第 1 作者, 专利号: CN109957119A

( 33 ) 一种κ-卡拉胶酶编码基因及其制备与应用, 发明专利, 2019, 第 1 作者, 专利号: CN109929859A

( 34 ) 一种岩藻多糖酶编码基因及酶的制备与应用, 发明专利, 2019, 第 1 作者, 专利号: CN109929860A

( 35 ) 多糖裂解单加氧酶LPMO 9D编码基因及酶与制备和应用, 发明专利, 2019, 第 1 作者, 专利号: CN109929855A

( 36 ) 一种葡甘聚糖酶编码基因及酶和制备与应用, 发明专利, 2019, 第 1 作者, 专利号: CN109929861A

( 37 ) 多糖裂解单加氧酶MtLPMO9G编码基因及其与制备和应用, 发明专利, 2019, 第 1 作者, 专利号: CN109929816A

( 38 ) 一种酶法催化二元醇制备二元胺的方法, 发明专利, 2019, 第 1 作者, 专利号: CN109897871A

( 39 ) 一种重组黑曲霉果胶酶及编码基因和制备与应用, 发明专利, 2019, 第 1 作者, 专利号: CN109868266A

( 40 ) 几丁寡糖在制备调节人或动物肠道菌群紊乱药物中的应用, 发明专利, 2019, 第 1 作者, 专利号: CN109833323A

( 41 ) 一种应用海洋寡糖提高刺参附着变态率的方法, 专利授权, 2019, 第 1 作者, 专利号: CN105613362B

( 42 ) 来源于酿酒酵母中几丁质脱乙酰酶及编码基因与应用, 发明专利, 2019, 第 1 作者, 专利号: CN109722429A

( 43 ) 一株产甘露醇的短乳杆菌菌株及其生产甘露醇的方法, 专利授权, 2019, 第 5 作者, 专利号: CN105002104B

( 44 ) 一种壳寡糖-褐藻酸纳米颗粒及其制备和应用, 发明专利, 2018, 第 1 作者, 专利号: CN108056101A

( 45 ) AtAGM2与AtAGM3编码基因及酶的制备与应用, 发明专利, 2018, 第 1 作者, 专利号: CN108611344A

( 46 ) 一种螺旋藻多糖及其应用, 发明专利, 2018, 第 2 作者, 专利号: CN105707072B

( 47 ) 一种内切纤维素酶编码基因及其制备与应用, 发明专利, 2018, 第 1 作者, 专利号: CN108220309A

( 48 ) 一种调节雌性动物繁殖性能的功能性单糖饲料及其应用, 发明专利, 2018, 第 1 作者, 专利号: CN104543416B

( 49 ) 一种产甘露糖的基因工程菌及表达方法和甘露糖制备, 发明专利, 2018, 第 2 作者, 专利号: CN108148795A

( 50 ) 一种用于促进小麦分蘖的壳寡糖复配制剂及其应用, 发明专利, 2018, 第 1 作者, 专利号: CN104705345B

( 51 ) 一种提高雌性动物繁殖性能的功能糖复合物及其应用, 发明专利, 2018, 第 1 作者, 专利号: CN104431341B

( 52 ) 一种改善母猪奶水中乳汁寡糖的饲料添加剂预混剂及其使用方法, 发明专利, 2018, 第 1 作者, 专利号: CN104920809B

( 53 ) 一种低温生产几丁质酶的菌株及其发酵方法, 发明专利, 2018, 第 1 作者, 专利号: CN104893997B

( 54 ) 一种PHA合酶和编码基因及其制备和应用, 发明专利, 2017, 第 1 作者, 专利号: CN107418963A

( 55 ) 一种提高断奶雌性动物卵泡发育能力的功能糖复合物及其应用, 发明专利, 2017, 第 1 作者, 专利号: CN104431340B

( 56 ) 一种乙酰乙酰辅酶A还原酶和编码基因及其制备和应用, 发明专利, 2017, 第 1 作者, 专利号: CN107418960A

( 57 ) 一种硫解酶和编码基因及其制备和应用, 发明专利, 2017, 第 1 作者, 专利号: CN107418962A

( 58 ) 一种以甲醇为能源和碳源生产聚羟基丁酸酯的方法, 发明专利, 2017, 第 1 作者, 专利号: CN106884022A

( 59 ) 一种广谱的植物保花保果剂及其应用, 发明专利, 2017, 第 4 作者, 专利号: CN106818751A

( 60 ) 一种广谱性寡糖复配杀菌剂及其应用, 发明专利, 2017, 第 3 作者, 专利号: CN106804594A

( 61 ) 一种生物法联产甘露醇与葡萄糖酸或葡萄糖酸盐的方法, 发明专利, 2017, 第 2 作者, 专利号: CN106811488A

( 62 ) 一种蔬果保鲜方法, 发明专利, 2017, 第 1 作者, 专利号: CN106720243A

( 63 ) 一种内切β-1,3-葡聚糖酶编码基因及其酶和制备方法与应用, 发明专利, 2017, 第 1 作者, 专利号: CN106755012A

( 64 ) 一种多糖裂解单加氧酶LPMO M1编码基因及其酶与制备方法和应用, 发明专利, 2017, 第 1 作者, 专利号: CN106754987A

( 65 ) 一种多糖裂解单加氧酶LPMO M2编码基因及其酶与制备方法和应用, 发明专利, 2017, 第 1 作者, 专利号: CN106755011A

( 66 ) 一种糖基化的5-羟甲基糠醛氧化酶及其制备, 发明专利, 2017, 第 1 作者, 专利号: CN106554946A

( 67 ) 内切褐藻胶裂解酶Alg2B及编码基因和制备与应用, 发明专利, 2016, 第 1 作者, 专利号: CN105821063A

( 68 ) 一种生物法制备甘露糖的方法, 发明专利, 2016, 第 2 作者, 专利号: CN105734096A

( 69 ) 一种褐藻胶裂解酶Alga及其编码基因和应用, 发明专利, 2016, 第 1 作者, 专利号: CN105713889A

( 70 ) 一种提取制备螺旋藻可溶性多糖的方法, 发明专利, 2016, 第 2 作者, 专利号: CN105646724A

( 71 ) 一种刺参专用复合海洋寡糖饲料添加剂及其制备和应用, 发明专利, 2016, 第 2 作者, 专利号: CN105614019A

( 72 ) 功能性寡糖在调节雌性动物子宫发育性能中应用, 发明专利, 2016, 第 1 作者, 专利号: CN105265753A

( 73 ) 壳寡糖在提高动物黄体数、胚胎着床、胎儿发育能力中应用, 发明专利, 2016, 第 1 作者, 专利号: CN105250327A

( 74 ) 一种壳寡糖复合物及其在缓解禾本科作物白化苗中的应用, 发明专利, 2015, 第 1 作者, 专利号: CN104649807A

( 75 ) 一种广谱性寡糖复配杀菌剂及其应用, 发明专利, 2015, 第 2 作者, 专利号: CN104798789A

( 76 ) 一种缓解农作物除草剂药害的方法, 发明专利, 2015, 第 3 作者, 专利号: CN104798776A

( 77 ) 一种用于改善小麦麦粒品质的壳寡糖复配制剂及其应用, 发明专利, 2015, 第 1 作者, 专利号: CN104705302A

( 78 ) 一种用于提高小麦产量的壳寡糖复配制剂及其应用, 发明专利, 2015, 第 1 作者, 专利号: CN104710231A

( 79 ) 一种壳寡糖复配制剂及其在延长水果货架期中的应用, 发明专利, 2015, 第 1 作者, 专利号: CN104642528A

( 80 ) 一种海藻酸钠寡糖包膜型缓释肥料及其制备和应用, 发明专利, 2015, 第 1 作者, 专利号: CN104649806A

( 81 ) 一种广谱的植物抗旱剂及其在作物抗旱中的应用, 发明专利, 2014, 第 4 作者, 专利号: CN104094933A

( 82 ) 一种酶解制备褐藻胶寡糖的方法, 发明专利, 2014, 第 4 作者, 专利号: CN104099386A

( 83 ) 含海藻酸钠寡糖的叶面肥组合物及其应用, 发明专利, 2013, 第 4 作者, 专利号: CN103011968A

( 84 ) 一种卡拉胶降解菌及其发酵方法和应用, 发明专利, 2013, 第 5 作者, 专利号: CN102994408A

( 85 ) 一种以壳寡糖为有效成分的农药残留降解剂及其应用, 发明专利, 2013, 第 5 作者, 专利号: CN102986661A

( 86 ) 壳寡糖及其衍生物在植物防冻抗寒中的应用, 发明专利, 2012, 第 4 作者, 专利号: CN102771476A

( 87 ) 壳寡糖及其衍生物在植物保花保果中的应用, 发明专利, 2012, 第 4 作者, 专利号: CN102771477A

( 88 ) 一种可德兰寡糖的应用, 发明专利, 2012, 第 6 作者, 专利号: CN102308800A

( 89 ) 一种饲料添加剂及其应用, 发明专利, 2011, 第 2 作者, 专利号: CN102058017A

( 90 ) 一种油菜促分裂原活化蛋白激酶基因及其编码蛋白, 发明专利, 2010, 第 2 作者, 专利号: CN101768595A

出版信息


发表论文
[1] Chemical Engineering Journal. 2024,   通讯作者  
[2] Carbohydrate Polymers. 2024,   通讯作者  
[3] Science. 2024, 第 10 作者
[4] Journal of Biological Chemistry. 2024,   通讯作者  
[5] The Plant Journal. 2023,   通讯作者  
[6] Jia, Xiaochen, Zhang, Hongyan, Qin, Hongqiang, Li, Kuikui, Liu, Xiaoyan, Wang, Wenxia, Ye, Mingliang, Yin, Heng. Protein O-GlcNAcylation impairment caused by N-acetylglucosamine phosphate mutase deficiency leads to growth variations in Arabidopsis thaliana. PLANT JOURNAL[J]. 2023, 第 8 作者  通讯作者  114(3): 613-635, http://dx.doi.org/10.1111/tpj.16156.
[7] 宋晓慧, 李悝悝, 赵秒, 李唐, 尹恒. 曲霉来源果胶裂解酶PnlF的克隆表达及酶学性质分析. 食品与发酵工业[J]. 2023, 第 5 作者49(1): 25-32, http://lib.cqvip.com/Qikan/Article/Detail?id=7108757307.
[8] Zhang, Huiyan, Zhou, Haichuan, Zhao, Yong, Li, Tang, Yin, Heng. Comparative studies of two AA10 family lytic polysaccharide monooxygenases from Bacillus thuringiensis. PEERJ[J]. 2023, 第 5 作者  通讯作者  11: http://dx.doi.org/10.7717/peerj.14670.
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[130] 王晓辉, 赵勇, 赵小明, 尹恒, 杜昱光. 海洋低温几丁质酶菌株筛选、鉴定及酶谱分析. 西北农业学报[J]. 2014, 第 4 作者23(9): 92, http://www.irgrid.ac.cn/handle/1471x/945696.
[131] Peng, Qiang, Xu, Qingsong, Yin, Heng, Huang, Linjuan, Du, Yuguang. Characterization of an immunologically active pectin from the fruits of Lycium ruthenicum. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2014, 第 3 作者64(1): 69-75, http://dx.doi.org/10.1016/j.ijbiomac.2013.11.030.
[132] 张运红, 赵小明, 尹恒, 和爱玲, 孙克刚. 寡糖浸种对小麦种子萌发及幼苗生长的影响. 河南农业科学[J]. 2014, 第 3 作者43(6): 16-21, http://lib.cqvip.com/Qikan/Article/Detail?id=50264409.
[133] 孟彦羽, 岳敏, 张建平, 王梦雨, 赵勇, 尹恒, 杜昱光. 海南土地杆菌Pedobacter hainanensis 13-QT发酵生产k-卡拉胶酶的条件优化. 中国酿造[J]. 2013, 第 6 作者32(7): 20, http://159.226.238.44/handle/321008/119332.
[134] Zhang, Yunhong, Yin, Heng, Wang, Wenxia, Zhao, Xiaoming, Du, Yuguang, Wu, Lishu. Enhancement in photosynthesis characteristics and phytohormones of flowering Chinese cabbage (Brassica campestris L. var. utilis Tsen et Lee) by exogenous alginate oligosaccharides. JOURNAL OF FOOD AGRICULTURE & ENVIRONMENT[J]. 2013, 第 2 作者11(1): 669-675, http://www.irgrid.ac.cn/handle/1471x/858587.
[135] Yin, Heng, Li, Yan, Zhang, HongYan, Wang, WenXia, Lu, Hang, Grevsen, Kai, Zhao, Xiaoming, Du, Yuguang. CHITOSAN OLIGOSACCHARIDES-TRIGGERED INNATE IMMUNITY CONTRIBUTES TO OILSEED RAPE RESISTANCE AGAINST SCLEROTINIA SCLEROTIORUM. INTERNATIONAL JOURNAL OF PLANT SCIENCES[J]. 2013, 第 1 作者174(4): 722-732, http://159.226.238.44/handle/321008/119349.
[136] 孟庆山, 尹恒, 胡建恩, 杜昱光. 植物糖基转移酶在植物抗病过程中的研究进展. 生物技术通讯[J]. 2013, 第 2 作者290-293, http://lib.cqvip.com/Qikan/Article/Detail?id=45407661.
[137] Liu, Hang, Zhang, YunHong, Yin, Heng, Wang, WenXia, Zhao, XiaoMing, Du, YuGuang. Alginate oligosaccharides enhanced Triticum aestivum L. tolerance to drought stress. PLANT PHYSIOLOGY AND BIOCHEMISTRY[J]. 2013, 第 3 作者62(62): 33-40, http://dx.doi.org/10.1016/j.plaphy.2012.10.012.
[138] Zhang, Yunhong, Liu, Hang, Yin, Heng, Wang, Wenxia, Zhao, Xiaoming, Du, Yuguang. Nitric oxide mediates alginate oligosaccharides-induced root development in wheat (Triticum aestivum L.). PLANT PHYSIOLOGY AND BIOCHEMISTRY[J]. 2013, 第 3 作者71: 49-56, http://dx.doi.org/10.1016/j.plaphy.2013.06.023.
[139] Zhang, Y H, Yin, H, Liu, H, Wang, W X, Wu, L S, Zhao, X M, Du, Y G. Alginate oligosaccharides regulate nitrogen metabolism via calcium in Brassica campestris L. var. utilis Tsen et Lee. JOURNAL OF HORTICULTURAL SCIENCE & BIOTECHNOLOGY[J]. 2013, 88(4): 502-508, http://www.irgrid.ac.cn/handle/1471x/858164.
[140] 张建平, 曹海龙, 赵勇, 李曙光, 岳敏, 刘航, 尹恒, 杜昱光. 乳酸菌发酵蟹壳脱钙的菌株筛选及条件优化. 中国酿造[J]. 2013, 第 7 作者32(6): 31, http://159.226.238.44/handle/321008/119464.
[141] 刘航, 尹恒, 张运红, 赵小明, 杜昱光. 褐藻胶寡糖生物活性研究进展. 天然产物研究与开发. 2012, 第 2 作者201-204+228, [[["https://nxgp.cnki.net/kcms/detail?v=3uoqIhG8C46NmWw7YpEsKL-WhGHP2RH_rvhkj9MidOlEe6j7_doe0XhiEOhWYM068EfUuqe6CstX15o_erI21bpGvSIYODkP&uniplatform=NZKPT"]]].
[142] Zhang, Hongyan, Wang, Wenxia, Yin, Heng, Zhao, Xiaoming, Du, Yuguang. Oligochitosan induces programmed cell death in tobacco suspension cells. CARBOHYDRATE POLYMERS[J]. 2012, 第 3 作者87(3): 2270-2278, http://dx.doi.org/10.1016/j.carbpol.2011.10.059.
[143] Yin, Heng, Kjaer, Anders, Frette, Xavier C, Du, Yuguang, Christensen, Lars P, Jensen, Martin, Grevsen, Kai. Chitosan oligosaccharide and salicylic acid up-regulate gene expression differently in relation to the biosynthesis of artemisinin in Artemisia annua L.. PROCESS BIOCHEMISTRY[J]. 2012, 第 1 作者  通讯作者  47(11): 1559-1562, http://dx.doi.org/10.1016/j.procbio.2011.12.020.
[144] Guo, Weihua, Yin, Heng, Ye, Zhiqiang, Zhao, Xiaoming, Yuan, Jingli, Du, Yuguang. A comparison study on the interactions of two oligosaccharides with tobacco cells by time-resolved fluorometric method. CARBOHYDRATE POLYMERS[J]. 2012, 第 2 作者90(1): 491-495, http://dx.doi.org/10.1016/j.carbpol.2012.05.070.
[145] 尹恒, 赵小明, 杜昱光. 糖工程与绿色农业. 高科技与产业化[J]. 2012, 第 1 作者50-53, http://lib.cqvip.com/Qikan/Article/Detail?id=41499559.
[146] Yin, Heng, Frette, Xavier C, Christensen, Lars P, Grevsen, Kai. Chitosan Oligosaccharides Promote the Content of Polyphenols in Greek Oregano (Origanum vulgare ssp hirtum). JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2012, 第 1 作者60(1): 136-143, http://www.irgrid.ac.cn/handle/1471x/721722.
[147] 张洪艳, 王文霞, 尹恒, 卢航, 赵小明, 杜昱光. 壳寡糖诱导植物防御反应中一氧化氮信号的研究. 中国生物工程杂志[J]. 2011, 第 3 作者31(2): 18-22, https://manu60.magtech.com.cn/biotech/CN/Y2011/V31/I02/18.
[148] 尹恒, 赵小明, 王文霞, 杜昱光. 植物糖生物学与糖链植物疫苗. 生命科学[J]. 2011, 第 1 作者23(6): 598-604, http://lib.cqvip.com/Qikan/Article/Detail?id=38429678.
[149] Fu, Yunbin, Yin, Heng, Wang, Wenxia, Wang, Mengyu, Zhang, Hongyan, Zhao, Xiaoming, Du, Yuguang. beta-1,3-Glucan with different degree of polymerization induced different defense responses in tobacco. CARBOHYDRATE POLYMERS[J]. 2011, 第 2 作者86(2): 774-782, http://159.226.238.44/handle/321008/142280.
[150] 张洪艳, 王文霞, 尹恒, 卢航, 赵小明, 杜昱光. 壳寡糖诱导烟草细胞钙离子和一氧化氮的产生及其相互关系的研究. 中国第二届国际和海峡两岸甲壳素研讨会暨第七届甲壳素科学技术会议论文集. 2011, 第 3 作者87-0, http://159.226.238.44/handle/321008/115913.
[151] Zhang, Hongyan, Zhao, Xiaoming, Yang, Jinli, Yin, Heng, Wang, Wenxia, Lu, Hang, Du, Yuguang. Nitric oxide production and its functional link with OIPK in tobacco defense response elicited by chitooligosaccharide. PLANT CELL REPORTS[J]. 2011, 第 4 作者30(6): 1153-1162, http://dx.doi.org/10.1007/s00299-011-1024-z.
[152] Yunbin Fu, Heng Yin, Wenxia Wang, Mengyu Wang, Hongyan Zhang, Xiaoming Zhao, Yuguang Du. β-1,3-Glucan with different degree of polymerization induced different defense responses in tobacco. CARBOHYDRATE POLYMERS[J]. 2011, 第 2 作者86(2): 774-782, http://dx.doi.org/10.1016/j.carbpol.2011.05.022.
[153] 尹恒, 王文霞, 赵小明, 杜昱光, , , , . 植物糖生物学研究进展. 植物学报[J]. 2010, 第 1 作者45(5): 521-529, https://www.chinbullbotany.com/CN/10.3969/j.issn.1674-3466.2010.05.001.
[154] Yin Heng. Oligochitosan: A plant diseases vaccine.. Carbohydrate Polymers. 2010, 第 1 作者
[155] Yin, Heng, Zhao, Xiaoming, Bai, Xuefang, Du, Yuguang. Molecular Cloning and Characterization of a Brassica napus L. MAP Kinase Involved in Oligochitosan-Induced Defense Signaling. PLANT MOLECULAR BIOLOGY REPORTER[J]. 2010, 第 1 作者28(2): 292-301, http://159.226.238.44/handle/321008/141919.
[156] Lu, Hang, Zhao, Xiaoming, Wang, Wenxia, Yin, Heng, Xu, Junguang, Bai, Xuefang, Du, Yuguang. Inhibition effect on tobacco mosaic virus and regulation effect on calreticulin of oligochitosan in tobacco by induced Ca2+ influx. CARBOHYDRATE POLYMERS[J]. 2010, 第 4 作者82(1): 136-142, http://dx.doi.org/10.1016/j.carbpol.2010.04.049.
[157] Yin, Heng, Zhao, Xiaoming, Du, Yuguang. Oligochitosan: A plant diseases vaccine-A review. CARBOHYDRATE POLYMERS[J]. 2010, 第 1 作者82(1): 1-8, http://dx.doi.org/10.1016/j.carbpol.2010.03.066.
[158] 杨金丽, 赵小明, 尹恒, 张洪艳, 杜昱光. 酵母双杂交筛选OIPK相互作用蛋白. 应用与环境生物学报[J]. 2010, 第 3 作者16(4): 474-477, http://lib.cqvip.com/Qikan/Article/Detail?id=35019337.
[159] Yang, Jinli, Yin, Heng, Lu, Hang, Zhao, Xiaoming, Du, Yuguang. Molecular cloning, prokaryotic expression, and purification of an alternatively spliced oligochitosan-induced Ser/Thr protein kinase in tobacco. ISRAEL JOURNAL OF PLANT SCIENCES[J]. 2010, 第 2 作者58(1): 67-75, http://dx.doi.org/10.1560/IJPS.58.1.67.
[160] Li, Yan, Yin, Heng, Wang, Qing, Zhao, Xiaoming, Du, Yuguang, Li, Fenglan. Oligochitosan induced Brassica napus L. production of NO and H2O2 and their physiological function. CARBOHYDRATE POLYMERS[J]. 2009, 第 2 作者75(4): 612-617, http://dx.doi.org/10.1016/j.carbpol.2008.09.005.
[161] Yin, Heng, Du, Yuguang. A new method for identification the oligochitosan binding protein on tobacco plasma membrane. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY[J]. 2009, 第 1 作者153A(2): S217-S217, http://159.226.238.44/handle/321008/141533.
[162] 郭卫华, 尹恒, 赵小明, 杜昱光. 功能糖肥料及抗逆剂. 生物产业技术[J]. 2009, 第 2 作者68-72, http://lib.cqvip.com/Qikan/Article/Detail?id=31775705.
[163] Yin, Heng, Du, Yuguang, Zhang, Junzeng. Low Molecular Weight and Oligomeric Chitosans and Their Bioactivities. CURRENT TOPICS IN MEDICINAL CHEMISTRY[J]. 2009, 第 1 作者9(16): 1546-1559, http://dx.doi.org/10.2174/156802609789909795.
[164] 许青松, 麻攀, 尹恒, 白雪芳, 杜昱光. 功能糖的免疫调节作用. 生物产业技术[J]. 2009, 第 3 作者52-56, http://lib.cqvip.com/Qikan/Article/Detail?id=30113759.
[165] 尹恒, 许青松, 杜昱光. 功能糖在畜牧健康养殖中的应用. 生物产业技术[J]. 2009, 第 1 作者79-84, http://lib.cqvip.com/Qikan/Article/Detail?id=31196698.
[166] 尹恒, 赵小明, 杜昱光. 糖链植物疫苗及其产业化. 生物产业技术[J]. 2009, 第 1 作者63-67, http://lib.cqvip.com/Qikan/Article/Detail?id=32329122.
[167] Yin Heng, Zhao Xiaoming, Du YuGuang, IEEE. Cloning and Molecular Characterization of a SKP1 Gene from Brassica napus. 2009 3RD INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICAL ENGINEERING, VOLS 1-11. 2009, 第 1 作者393-395, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000286342800097.
[168] Yin, Heng, Bai, Xuefang, Du, Yuguang. The primary study of oligochitosan inducing resistance to Sclerotinia sclerotiorum on Brassica napus. JOURNAL OF BIOTECHNOLOGY[J]. 2008, 第 1 作者136: S600-S601, http://dx.doi.org/10.1016/j.jbiotec.2008.07.1217.
[169] Yin Heng. Nitric oxide and hydrogen peroxide signaling in B.napus resistance to S.sclerotiorum induced by oligochitosan. Glycobiology. 2008, 第 1 作者
[170] 杨金丽, 尹恒, 赵小明, 马小军, 杜昱光. 壳寡糖诱导的烟草Ser/Thr蛋白激酶的原核表达纯化及多克隆抗体的特异性检测. 西北农业学报[J]. 2008, 第 2 作者17(6): 253-257, http://lib.cqvip.com/Qikan/Article/Detail?id=28887552.
[171] 尹恒, 王文霞, 卢航, 赵小明, 白雪芳, 杜昱光. 壳寡糖诱导油菜抗菌核病机理研究初探. 西北农业学报[J]. 2008, 第 1 作者17(5): 81-85, http://lib.cqvip.com/Qikan/Article/Detail?id=28346061.
[172] Yin Heng. Primary Study of Oligochitosan Inducing Resistance to S.sclerotiorum on B.napus. J.Biotechnology. 2008, 第 1 作者
[173] 尹恒, 杨金丽, 李曙光, 赵小明, 白雪芳, 马小军, 杜昱光. 受壳寡糖诱导的油菜MAPK基因的克隆与分析. 作物学报[J]. 2008, 第 1 作者34(5): 743-747, http://lib.cqvip.com/Qikan/Article/Detail?id=27282749.
[174] 熊川男, 赵小明, 尹恒, 王焕弟, 杜昱光. 菊芋凝集素的分离鉴定及菊芋蛋白促进家兔离体回肠蠕动的研究. 西北农业学报[J]. 2008, 第 3 作者17(4): 137-142, http://lib.cqvip.com/Qikan/Article/Detail?id=27815443.
[175] Yin, H, Li, S, Zhao, X, Du, Y, Ma, X. cDNA microarray analysis of gene expression in Brassica napus treated with oligochitosan elicitor. PLANT PHYSIOLOGY AND BIOCHEMISTRY[J]. 2006, 44(11-12): 910-916, http://dx.doi.org/10.1016/j.plaphy.2006.10.002.
[176] 尹恒, 李曙光, 白雪芳, 杜昱光. 植物代谢组学的研究方法及其应用. 植物学通报[J]. 2005, 第 1 作者22(5): 532-540, http://lib.cqvip.com/Qikan/Article/Detail?id=20588950.
发表著作
(1) 壳寡糖的功能研究及应用, 化工出版社, 2009-01, 第 5 作者
(2) Chitin,Chitosan,Oligosaccharides and Their derivatives, CRC Press, 2010-05, 第 1 作者
(3) 糖生物工程, 化工出版社, 2012-08, 第 5 作者
(4) 糖链植物疫苗研究与应用, 科学出版社, 2012-10, 第 3 作者
(5) Research Progress in Oligosaccharins, Springer-Verlag Press, 2016-12, 第 1 作者

科研活动

   
科研项目
( 1 ) 烟草壳寡糖受体鉴定及其在诱抗过程中的功能确认, 负责人, 国家任务, 2012-01--2014-12
( 2 ) 褐藻胶裂解酶基因工程改造及褐藻胶寡糖制备技术研究, 负责人, 地方任务, 2011-06--2013-06
( 3 ) 新型海洋生物农用制剂产品开发, 参与, 国家任务, 2011-07--2017-07
( 4 ) 公益性行业(农业)科研专项新型寡糖植物疫苗的研制与产业化开发, 参与, 国家任务, 2009-12--2013-12
( 5 ) 海洋生物农药及植物促生长剂产业化关键技术研究, 参与, 国家任务, 2007-07--2010-06
( 6 ) 含CBM1结构域的多糖裂解单加氧酶鉴定及其底物结合机制研究, 参与, 国家任务, 2017-01--2020-12
( 7 ) 拟南芥磷酸N-乙酰氨基葡萄糖变位酶功能鉴定及其影响蛋白糖基化的研究, 参与, 国家任务, 2014-01--2017-12
( 8 ) 海藻寡糖饲料添加剂的制备及质量控制研究, 参与, 国家任务, 2013-01--2016-12
( 9 ) 中国科学院STS项目"新型糖类与微生物农药及抗逆剂创制及示范", 参与, 中国科学院计划, 2016-01--2017-12
( 10 ) 稻瘟病菌中多糖单加氧酶鉴定及功能解析, 参与, 地方任务, 2015-01--2017-12
( 11 ) 大连市高层次人才创新支持计划"新型海洋寡糖农用制剂研发及应用推广", 负责人, 地方任务, 2016-01--2018-12
( 12 ) 功能糖类免疫调控技术及产品研发, 负责人, 国家任务, 2017-07--2020-12
( 13 ) 多糖资源高值化转化利用, 负责人, 其他任务, 2018-01--2018-12
( 14 ) 拟南芥胞外含LysM结构域蛋白(AtLysMe)强化几丁寡糖信号识别的作 用机制研究, 负责人, 国家任务, 2020-01--2023-12
( 15 ) 功能寡糖制备及农用产品开发应用, 负责人, 地方任务, 2019-01--2021-12
( 16 ) 集成与示范绿色生物防控减肥减药技术, 负责人, 中国科学院计划, 2018-08--2019-12
( 17 ) 中国科学院青年创新促进会优秀会员, 负责人, 中国科学院计划, 2020-01--2022-12
( 18 ) 新型糖类农用制剂在一带一路国家种植业的应用示范, 负责人, 国家任务, 2021-01--2023-12
( 19 ) 海洋糖类生物质高值化利用技术研究及产品开发, 负责人, 地方任务, 2021-01--2023-12
( 20 ) 耐盐碱经济作物功能性 食品研发与产业化示范, 负责人, 中国科学院计划, 2020-01--2021-06
参与会议
(1)Oligosaccharides induce resistance to Pseudomonas syringae pv. tomato DC3000 in arabidopsis thaliana via distinct N-glycosylation regulation pattern    2019-08-25
(2) Chitosan oligosaccharides induce resistance to Pseudomonas syringae pv. tomato DC3000 in Arabidopsis thaliana via distinct N-glycosylation regulation pattern    2019-07-14
(3)Oligosaccharides plant immunity regulator development and application   2018-05-09
(4)Loss of N-Acetylglucosamine Phosphate Mutase Impair Protein Glycosylation ,Plant Growth and Defense Response in Arabidopsis.   2017-08-28
(5)Oligosaccharides based bio-pesticides development and application   2017-06-27
(6)A NOVEL METHOD TO DETERMINE PHOSPHOHEXOSE MUTASE ACTIVITY BY ANION-EXCHANGE CHROMATOGRAPHY WITH ELECTROCHEMICAL DETECTOR   2015-09-16

指导学生

已指导学生

于作琛  硕士研究生  085238-生物工程  

张鑫  硕士研究生  081703-生物化工  

吴凡  硕士研究生  081703-生物化工  

贾晓晨  博士研究生  081703-生物化工  

周海川  博士研究生  081703-生物化工  

杨国军  博士研究生  081703-生物化工  

现指导学生

宋荔琳  博士研究生  081703-生物化工  

王宇  博士研究生  081703-生物化工  

陈长峥  硕士研究生  086000-生物与医药  

高娃  博士研究生  081703-生物化工  

谷慧  博士研究生  081703-生物化工  

许正阳  硕士研究生  086000-生物与医药  

郑杨洁  硕士研究生  081703-生物化工  

覃杰  博士研究生  081703-生物化工  

张晓静  博士研究生  081703-生物化工  

孙楠  硕士研究生  081703-生物化工