基本信息
何茂洲 男 硕导 杭州高等研究院
电子邮件： hemaozhou@ucas.ac.cn
通信地址： 浙江省杭州市西湖区象山支弄1号国科大杭州高等研究院
邮政编码：
电子邮件： hemaozhou@ucas.ac.cn
通信地址： 浙江省杭州市西湖区象山支弄1号国科大杭州高等研究院
邮政编码：
招生信息
招生专业
100706-药理学
071011-生物物理学
071010-生物化学与分子生物学
071011-生物物理学
071010-生物化学与分子生物学
招生方向
GPCR动态调控的分子机理研究，GPCR相关药物开发（如抗体等）
人类大分子机器的结构与功能研究
病毒与宿主相互作用的分子机制研究
人类大分子机器的结构与功能研究
病毒与宿主相互作用的分子机制研究
教育背景
2014-09--2020-08 厦门大学 理学博士
2009-09--2014-07 南昌大学 医学学士
2009-09--2014-07 南昌大学 医学学士
工作经历
工作简历
2023-03~现在, 国科大杭州高等研究院, 副研究员
2022-09~2023-03,国科大杭州高等研究院, 助理研究员
2020-09~2022-09,西湖大学, 博士后
2022-09~2023-03,国科大杭州高等研究院, 助理研究员
2020-09~2022-09,西湖大学, 博士后
教授课程
实验数据处理
生物大分子结构确证技术概要
生物大分子冷冻电镜样品制备与三维重构
生物大分子结构确证技术概要
生物大分子冷冻电镜样品制备与三维重构
专利与奖励
专利成果
（ 1 ） Mutant of L1 protein of human papillomavirus type 16, 发明专利, 2022, 第 4 作者, 专利号: US11213580(B2)
（ 2 ） MUTANT OF L1 PROTEIN OF HUMAN PAPILLOMAVIRUS TYPE 58, 专利授权, 2020, 第 4 作者, 专利号: US2020/0268869(A1)
（ 3 ） 一种人乳头瘤病毒18型L1蛋白的突变体, 发明专利, 2019, 第 3 作者, 专利号: CN110551182A
（ 4 ） 一种人乳头瘤病毒45型L1蛋白的突变体, 发明专利, 2019, 第 2 作者, 专利号: CN110551186A
（ 5 ） 一种人乳头瘤病毒35型L1蛋白的突变体, 发明专利, 2019, 第 4 作者, 专利号: CN109251236A
（ 6 ） 一种人乳头瘤病毒16型L1蛋白的突变体, 专利授权, 2019, 第 4 作者, 专利号: CN109251235A
（ 7 ） 一种人乳头瘤病毒58型L1蛋白的突变体, 专利授权, 2017, 第 4 作者, 专利号: CN106831961A
（ 2 ） MUTANT OF L1 PROTEIN OF HUMAN PAPILLOMAVIRUS TYPE 58, 专利授权, 2020, 第 4 作者, 专利号: US2020/0268869(A1)
（ 3 ） 一种人乳头瘤病毒18型L1蛋白的突变体, 发明专利, 2019, 第 3 作者, 专利号: CN110551182A
（ 4 ） 一种人乳头瘤病毒45型L1蛋白的突变体, 发明专利, 2019, 第 2 作者, 专利号: CN110551186A
（ 5 ） 一种人乳头瘤病毒35型L1蛋白的突变体, 发明专利, 2019, 第 4 作者, 专利号: CN109251236A
（ 6 ） 一种人乳头瘤病毒16型L1蛋白的突变体, 专利授权, 2019, 第 4 作者, 专利号: CN109251235A
（ 7 ） 一种人乳头瘤病毒58型L1蛋白的突变体, 专利授权, 2017, 第 4 作者, 专利号: CN106831961A
出版信息
发表论文
[1] Zheng, Qingbing, Zhu, Rui, Yin, Zhichao, Xu, Longfa, Sun, Hui, Yu, Hai, Wu, Yuanyuan, Jiang, Yichao, Huang, Qiongzi, Huang, Yang, Zhang, Dongqing, Liu, Liqin, Yang, Hongwei, He, Maozhou, Zhou, Zhenhong, Jiang, Yanan, Chen, Zhenqin, Zhao, Huan, Que, Yuqiong, Kong, Zhibo, Zhou, Lizhi, Li, Tingting, Zhang, Jun, Luo, Wenxin, Gu, Ying, Cheng, Tong, Li, Shaowei, Xia, Ningshao. Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. CELL HOST & MICROBE[J]. 2022, 30(9): 1279-+, http://dx.doi.org/10.1016/j.chom.2022.08.001.
[2] Li, Tingting, Chen, Junyu, Zheng, Qingbing, Xue, Wenhui, Zhang, Limin, Rong, Rui, Zhang, Sibo, Wang, Qian, Hong, Minqing, Zhang, Yuyun, Cui, Lingyan, He, Maozhou, Lu, Zhen, Zhang, Zhenyong, Chi, Xin, Li, Jinjin, Huang, Yang, Wang, Hong, Tang, Jixian, Ying, Dong, Zhou, Lizhi, Wang, Yingbin, Yu, Hai, Zhang, Jun, Gu, Ying, Chen, Yixin, Li, Shaowei, Xia, Ningshao. Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses. NATURE COMMUNICATIONS[J]. 2022, 13(1): http://dx.doi.org/10.1038/s41467-022-32926-5.
[3] Wang, Guosong, Zha, Zhenghui, Huang, Pengfei, Sun, Hui, Huang, Yang, He, Maozhou, Chen, Tian, Lin, Lina, Chen, Zhenqin, Kong, Zhibo, Que, Yuqiong, Li, Tingting, Gu, Ying, Yu, Hai, Zhang, Jun, Zheng, Qingbing, Chen, Yixin, Li, Shaowei, Xia, Ningshao. Structures of pseudorabies virus capsids. NATURE COMMUNICATIONS[J]. 2022, 13(1): http://dx.doi.org/10.1038/s41467-022-29250-3.
[4] He, Maozhou, Chi, Xin, Zha, Zhenghui, Li, Yunbing, Huang, Yang, Huang, Shiwen, Yu, Miao, Wang, Zhiping, Liu, Xinlin, Wei, Shuangping, Li, Zekai, Li, Tingting, Wang, Yingbin, Yu, Hai, Zhao, Qinjian, Zhang, Jun, Zheng, Qingbing, Gu, Ying, Li, Shaowei, Xia, Ningsha. Structural Basis for the Shared Neutralization Mechanism of Three Classes of Human Papillomavirus Type 58 Antibodies with Disparate Modes of Binding. JOURNAL OF VIROLOGY[J]. 2021, 95(7): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092703/.
[5] Xu, Longfa, Zheng, Qingbing, Zhu, Rui, Yin, Zhichao, Yu, Hai, Lin, Yu, Wu, Yuanyuan, He, Maozhou, Huang, Yang, Jiang, Yichao, Sun, Hui, Zha, Zhenghui, Yang, Hongwei, Huang, Qiongzi, Zhang, Dongqing, Chen, Zhenqin, Ye, Xiangzhong, Han, Jinle, Yang, Lisheng, Liu, Che, Que, Yuqiong, Fang, Mujin, Gu, Ying, Zhang, Jun, Luo, Wenxin, Zhou, Z Hong, Li, Shaowei, Cheng, Tong, Xia, Ningshao. Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating. CELL HOST & MICROBE[J]. 2021, 29(3): 448-+, http://dx.doi.org/10.1016/j.chom.2021.01.001.
[6] Huang, Weijin, He, Maozhou, Ning, Tingting, Nie, Jianhui, Zhang, Feng, Zheng, Qingbing, Zhang, Rui, Xu, Ying, Gu, Ying, Li, Shaowei, Wang, Youchun. Structural characterization of a neutralizing mAb H16.001, a potent candidate for a common potency assay for various HPV16 VLPs. NPJ VACCINES[J]. 2020, 5(1): http://dx.doi.org/10.1038/s41541-020-00236-w.
[7] Wang, Wei, Zheng, Qingbing, Pan, Dequan, Yu, Hai, Fu, Wenkun, Liu, Jian, He, Maozhou, Zhu, Rui, Cai, Yuze, Huang, Yang, Zha, Zhenghui, Chen, Zhenqin, Ye, Xiangzhong, Han, Jinle, Que, Yuqiong, Wu, Ting, Zhang, Jun, Li, Shaowei, Zhu, Hua, Zhou, Z Hong, Cheng, Tong, Xia, Ningshao. Near-atomic cryo-electron microscopy structures of varicella-zoster virus capsids. NATURE MICROBIOLOGY[J]. 2020, 5(12): 1542-+, http://dx.doi.org/10.1038/s41564-020-0785-y.
[8] Zhou, Bing, Xia, Lin, Zhang, Tianying, You, Min, Huang, Yang, He, Maozhou, Su, Ruopeng, Tang, Jixian, Zhang, Juan, Li, Shaowei, An, Zhiqiang, Yuan, Quan, Luo, Wenxin, Xia, Ningshao. Structure guided maturation of a novel humanized anti-HBV antibody and its preclinical development. ANTIVIRAL RESEARCH[J]. 2020, 180: http://dx.doi.org/10.1016/j.antiviral.2020.104757.
[9] He, Maozhou, Xu, Longfa, Zheng, Qingbing, Zhu, Rui, Yin, Zhichao, Zha, Zhenghui, Lin, Yu, Yang, Lisheng, Huang, Yang, Ye, Xiangzhong, Li, Shuxuan, Hou, Wangheng, Wu, Yangtao, Han, Jinle, Liu, Dongxiao, Li, Zekai, Chen, Zhenqin, Yu, Hai, Que, Yuqiong, Wang, Yingbin, Yan, Xiaodong, Zhang, Jun, Gu, Ying, Zhou, Z Hong, Cheng, Tong, Li, Shaowei, Xia, Ningshao. Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16. CELL HOST & MICROBE[J]. 2020, 27(2): 249-+, http://dx.doi.org/10.1016/j.chom.2020.01.003.
[10] Liu, Xinlin, Chen, Jie, Wang, Zhiping, Wang, Daning, He, Maozhou, Qian, Ciying, Song, Shuo, Chi, Xin, Kong, Zhibo, Zheng, Qingbing, Wang, Yingbin, Yu, Hai, Zhao, Qinjian, Zhang, Jun, Li, Shaowei, Gu, Ying, Xia, Ningshao. Neutralization sites of human papillomavirus-6 relate to virus attachment and entry phase in viral infection. EMERGING MICROBES & INFECTIONS[J]. 2019, 8(1): 1721-1733, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000499253500001.
[11] Zheng, Qingbing, Zhu, Rui, Xu, Longfa, He, Maozhou, Yan, Xiaodong, Liu, Dongxiao, Yin, Zhichao, Wu, Yangtao, Li, Yongchao, Yang, Lisheng, Hou, Wangheng, Li, Shuxuan, Li, Zizhen, Chen, Zhenqin, Li, Zhihai, Yu, Hai, Gu, Ying, Zhang, Jun, Baker, Timothy S, Zhou, Z Hong, Graham, Barney S, Cheng, Tong, Li, Shaowei, Xia, Ningshao. Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization. NATURE MICROBIOLOGY[J]. 2019, 4(1): 124-+, [12] Zheng, Qingbing, Jiang, Jie, He, Maozhou, Zheng, Zizheng, Yu, Hai, Li, Tingting, Xue, Wenhui, Tang, Zimin, Ying, Dong, Li, Zekai, Song, Shuo, Liu, Xinlin, Wang, Kaihang, Zhang, Zhiqing, Wang, Daning, Wang, Yingbin, Yan, Xiaodong, Zhao, Qinjian, Zhang, Jun, Gu, Ying, Li, Shaowei, Xia, Ningshao. Viral neutralization by antibody-imposed physical disruption. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2019, 116(52): 26933-26940, [13] Zhu, Rui, Xu, Longfa, Zheng, Qingbing, Cui, Yanxiang, Li, Shaowei, He, Maozhou, Yin, Zhichao, Liu, Dongxiao, Li, Shuxuan, Li, Zizhen, Chen, Zhenqin, Yu, Hai, Que, Yuqiong, Liu, Che, Kong, Zhibo, Zhang, Jun, Baker, Timothy S, Yan, Xiaodong, Zhou, Z Hong, Cheng, Tong, Xia, Ningshao. Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10. SCIENCE ADVANCES[J]. 2018, 4(9): https://www.webofscience.com/wos/woscc/full-record/WOS:000449224000039.
[14] Zhang, Zhiqing, He, Maozhou, Bai, Shimeng, Zhang, Feng, Jiang, Jie, Zheng, Qingbing, Gao, Shuangquan, Yan, Xiaodong, Li, Shaowei, Gu, Ying, Xia, Ningshao. T=4 Icosahedral HIV-1 Capsid As an Immunogenic Vector for HIV-1 V3 Loop Epitope Display. VIRUSES-BASEL[J]. 2018, 10(12): https://doaj.org/article/cebde740e615410ba81541e5bda12de4.
[15] Minxi Wei, Daning Wang, Zhihai Li, Shuo Song, Xianglin Kong, Xiaobing Mo, Yurou Yang, Maozhou He, Zhongyi Li, Bo Huang, Zhijie Lin, Huirong Pan, Qingbing Zheng, Hai Yu, Ying Gu, Jun Zhang, Shaowei Li, Ningshao Xia. N-terminal truncations on L1 proteins of human papillomaviruses promote their soluble expression in Escherichia coli and self-assembly in vitro. EMERGING MICROBES AND INFECTIONS[J]. 2018, 7(1): 1-12, https://doaj.org/article/b6b67d340a8a46ba8106b45bc5019f4f.
[16] Zhihai Li, Shuo Song, Maozhou He, Daning Wang, Jingjie Shi, Xinlin Liu, Yunbing Li, Xin Chi, Shuangping Wei, Yurou Yang, Zhiping Wang, Jinjin Li, Huilian Qian, Hai Yu, Qingbing Zheng, Xiaodong Yan, Qinjian Zhao, Jun Zhang, Ying Gu, Shaowei Li, Ningshao Xia. Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity. NATURE COMMUNICATIONS[J]. 2018, 9(1): https://doaj.org/article/039219052ebb4aa9a0858559f58758cb.
[17] Longfa Xu, Qingbing Zheng, Shaowei Li, Maozhou He, Yangtao Wu, Yongchao Li, Rui Zhu, Hai Yu, Qiyang Hong, Jie Jiang, Zizhen Li, Shuxuan Li, Huan Zhao, Lisheng Yang, Wangheng Hou, Wei Wang, Xiangzhong Ye, Jun Zhang, Timothy S Baker, Tong Cheng, Z Hong Zhou, Xiaodong Yan, Ningshao Xia. Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody. NATURE COMMUNICATIONS[J]. 2017, 8(1): https://doaj.org/article/60d033d527464f0c92b4eeb9e9b5a39d.
[2] Li, Tingting, Chen, Junyu, Zheng, Qingbing, Xue, Wenhui, Zhang, Limin, Rong, Rui, Zhang, Sibo, Wang, Qian, Hong, Minqing, Zhang, Yuyun, Cui, Lingyan, He, Maozhou, Lu, Zhen, Zhang, Zhenyong, Chi, Xin, Li, Jinjin, Huang, Yang, Wang, Hong, Tang, Jixian, Ying, Dong, Zhou, Lizhi, Wang, Yingbin, Yu, Hai, Zhang, Jun, Gu, Ying, Chen, Yixin, Li, Shaowei, Xia, Ningshao. Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses. NATURE COMMUNICATIONS[J]. 2022, 13(1): http://dx.doi.org/10.1038/s41467-022-32926-5.
[3] Wang, Guosong, Zha, Zhenghui, Huang, Pengfei, Sun, Hui, Huang, Yang, He, Maozhou, Chen, Tian, Lin, Lina, Chen, Zhenqin, Kong, Zhibo, Que, Yuqiong, Li, Tingting, Gu, Ying, Yu, Hai, Zhang, Jun, Zheng, Qingbing, Chen, Yixin, Li, Shaowei, Xia, Ningshao. Structures of pseudorabies virus capsids. NATURE COMMUNICATIONS[J]. 2022, 13(1): http://dx.doi.org/10.1038/s41467-022-29250-3.
[4] He, Maozhou, Chi, Xin, Zha, Zhenghui, Li, Yunbing, Huang, Yang, Huang, Shiwen, Yu, Miao, Wang, Zhiping, Liu, Xinlin, Wei, Shuangping, Li, Zekai, Li, Tingting, Wang, Yingbin, Yu, Hai, Zhao, Qinjian, Zhang, Jun, Zheng, Qingbing, Gu, Ying, Li, Shaowei, Xia, Ningsha. Structural Basis for the Shared Neutralization Mechanism of Three Classes of Human Papillomavirus Type 58 Antibodies with Disparate Modes of Binding. JOURNAL OF VIROLOGY[J]. 2021, 95(7): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092703/.
[5] Xu, Longfa, Zheng, Qingbing, Zhu, Rui, Yin, Zhichao, Yu, Hai, Lin, Yu, Wu, Yuanyuan, He, Maozhou, Huang, Yang, Jiang, Yichao, Sun, Hui, Zha, Zhenghui, Yang, Hongwei, Huang, Qiongzi, Zhang, Dongqing, Chen, Zhenqin, Ye, Xiangzhong, Han, Jinle, Yang, Lisheng, Liu, Che, Que, Yuqiong, Fang, Mujin, Gu, Ying, Zhang, Jun, Luo, Wenxin, Zhou, Z Hong, Li, Shaowei, Cheng, Tong, Xia, Ningshao. Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating. CELL HOST & MICROBE[J]. 2021, 29(3): 448-+, http://dx.doi.org/10.1016/j.chom.2021.01.001.
[6] Huang, Weijin, He, Maozhou, Ning, Tingting, Nie, Jianhui, Zhang, Feng, Zheng, Qingbing, Zhang, Rui, Xu, Ying, Gu, Ying, Li, Shaowei, Wang, Youchun. Structural characterization of a neutralizing mAb H16.001, a potent candidate for a common potency assay for various HPV16 VLPs. NPJ VACCINES[J]. 2020, 5(1): http://dx.doi.org/10.1038/s41541-020-00236-w.
[7] Wang, Wei, Zheng, Qingbing, Pan, Dequan, Yu, Hai, Fu, Wenkun, Liu, Jian, He, Maozhou, Zhu, Rui, Cai, Yuze, Huang, Yang, Zha, Zhenghui, Chen, Zhenqin, Ye, Xiangzhong, Han, Jinle, Que, Yuqiong, Wu, Ting, Zhang, Jun, Li, Shaowei, Zhu, Hua, Zhou, Z Hong, Cheng, Tong, Xia, Ningshao. Near-atomic cryo-electron microscopy structures of varicella-zoster virus capsids. NATURE MICROBIOLOGY[J]. 2020, 5(12): 1542-+, http://dx.doi.org/10.1038/s41564-020-0785-y.
[8] Zhou, Bing, Xia, Lin, Zhang, Tianying, You, Min, Huang, Yang, He, Maozhou, Su, Ruopeng, Tang, Jixian, Zhang, Juan, Li, Shaowei, An, Zhiqiang, Yuan, Quan, Luo, Wenxin, Xia, Ningshao. Structure guided maturation of a novel humanized anti-HBV antibody and its preclinical development. ANTIVIRAL RESEARCH[J]. 2020, 180: http://dx.doi.org/10.1016/j.antiviral.2020.104757.
[9] He, Maozhou, Xu, Longfa, Zheng, Qingbing, Zhu, Rui, Yin, Zhichao, Zha, Zhenghui, Lin, Yu, Yang, Lisheng, Huang, Yang, Ye, Xiangzhong, Li, Shuxuan, Hou, Wangheng, Wu, Yangtao, Han, Jinle, Liu, Dongxiao, Li, Zekai, Chen, Zhenqin, Yu, Hai, Que, Yuqiong, Wang, Yingbin, Yan, Xiaodong, Zhang, Jun, Gu, Ying, Zhou, Z Hong, Cheng, Tong, Li, Shaowei, Xia, Ningshao. Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16. CELL HOST & MICROBE[J]. 2020, 27(2): 249-+, http://dx.doi.org/10.1016/j.chom.2020.01.003.
[10] Liu, Xinlin, Chen, Jie, Wang, Zhiping, Wang, Daning, He, Maozhou, Qian, Ciying, Song, Shuo, Chi, Xin, Kong, Zhibo, Zheng, Qingbing, Wang, Yingbin, Yu, Hai, Zhao, Qinjian, Zhang, Jun, Li, Shaowei, Gu, Ying, Xia, Ningshao. Neutralization sites of human papillomavirus-6 relate to virus attachment and entry phase in viral infection. EMERGING MICROBES & INFECTIONS[J]. 2019, 8(1): 1721-1733, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000499253500001.
[11] Zheng, Qingbing, Zhu, Rui, Xu, Longfa, He, Maozhou, Yan, Xiaodong, Liu, Dongxiao, Yin, Zhichao, Wu, Yangtao, Li, Yongchao, Yang, Lisheng, Hou, Wangheng, Li, Shuxuan, Li, Zizhen, Chen, Zhenqin, Li, Zhihai, Yu, Hai, Gu, Ying, Zhang, Jun, Baker, Timothy S, Zhou, Z Hong, Graham, Barney S, Cheng, Tong, Li, Shaowei, Xia, Ningshao. Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization. NATURE MICROBIOLOGY[J]. 2019, 4(1): 124-+, [12] Zheng, Qingbing, Jiang, Jie, He, Maozhou, Zheng, Zizheng, Yu, Hai, Li, Tingting, Xue, Wenhui, Tang, Zimin, Ying, Dong, Li, Zekai, Song, Shuo, Liu, Xinlin, Wang, Kaihang, Zhang, Zhiqing, Wang, Daning, Wang, Yingbin, Yan, Xiaodong, Zhao, Qinjian, Zhang, Jun, Gu, Ying, Li, Shaowei, Xia, Ningshao. Viral neutralization by antibody-imposed physical disruption. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2019, 116(52): 26933-26940, [13] Zhu, Rui, Xu, Longfa, Zheng, Qingbing, Cui, Yanxiang, Li, Shaowei, He, Maozhou, Yin, Zhichao, Liu, Dongxiao, Li, Shuxuan, Li, Zizhen, Chen, Zhenqin, Yu, Hai, Que, Yuqiong, Liu, Che, Kong, Zhibo, Zhang, Jun, Baker, Timothy S, Yan, Xiaodong, Zhou, Z Hong, Cheng, Tong, Xia, Ningshao. Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10. SCIENCE ADVANCES[J]. 2018, 4(9): https://www.webofscience.com/wos/woscc/full-record/WOS:000449224000039.
[14] Zhang, Zhiqing, He, Maozhou, Bai, Shimeng, Zhang, Feng, Jiang, Jie, Zheng, Qingbing, Gao, Shuangquan, Yan, Xiaodong, Li, Shaowei, Gu, Ying, Xia, Ningshao. T=4 Icosahedral HIV-1 Capsid As an Immunogenic Vector for HIV-1 V3 Loop Epitope Display. VIRUSES-BASEL[J]. 2018, 10(12): https://doaj.org/article/cebde740e615410ba81541e5bda12de4.
[15] Minxi Wei, Daning Wang, Zhihai Li, Shuo Song, Xianglin Kong, Xiaobing Mo, Yurou Yang, Maozhou He, Zhongyi Li, Bo Huang, Zhijie Lin, Huirong Pan, Qingbing Zheng, Hai Yu, Ying Gu, Jun Zhang, Shaowei Li, Ningshao Xia. N-terminal truncations on L1 proteins of human papillomaviruses promote their soluble expression in Escherichia coli and self-assembly in vitro. EMERGING MICROBES AND INFECTIONS[J]. 2018, 7(1): 1-12, https://doaj.org/article/b6b67d340a8a46ba8106b45bc5019f4f.
[16] Zhihai Li, Shuo Song, Maozhou He, Daning Wang, Jingjie Shi, Xinlin Liu, Yunbing Li, Xin Chi, Shuangping Wei, Yurou Yang, Zhiping Wang, Jinjin Li, Huilian Qian, Hai Yu, Qingbing Zheng, Xiaodong Yan, Qinjian Zhao, Jun Zhang, Ying Gu, Shaowei Li, Ningshao Xia. Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity. NATURE COMMUNICATIONS[J]. 2018, 9(1): https://doaj.org/article/039219052ebb4aa9a0858559f58758cb.
[17] Longfa Xu, Qingbing Zheng, Shaowei Li, Maozhou He, Yangtao Wu, Yongchao Li, Rui Zhu, Hai Yu, Qiyang Hong, Jie Jiang, Zizhen Li, Shuxuan Li, Huan Zhao, Lisheng Yang, Wangheng Hou, Wei Wang, Xiangzhong Ye, Jun Zhang, Timothy S Baker, Tong Cheng, Z Hong Zhou, Xiaodong Yan, Ningshao Xia. Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody. NATURE COMMUNICATIONS[J]. 2017, 8(1): https://doaj.org/article/60d033d527464f0c92b4eeb9e9b5a39d.
科研活动
科研项目
（ 1 ） 博士后创新人才支持计划, 负责人, 国家任务, 2020-09--2022-09
（ 2 ） 浙江省博士后科研项目择优资助，一等资助, 负责人, 地方任务, 2020-09--2022-09
（ 3 ） 人源黏连蛋白动态过程与调控机制, 参与, 国家任务, 2022-01--2026-12
（ 4 ） 结构指导的免疫原设计及广谱保护机制研究, 参与, 国家任务, 2020-01--2024-12
（ 5 ） 国科大杭高院引进人才项目启动经费, 负责人, 研究所自主部署, 2023-05--2025-12
（ 6 ） 非激活态趋化素-趋化因子样受体CMKLR1的结构和功 能研究, 负责人, 地方任务, 2024-01--2026-12
（ 2 ） 浙江省博士后科研项目择优资助，一等资助, 负责人, 地方任务, 2020-09--2022-09
（ 3 ） 人源黏连蛋白动态过程与调控机制, 参与, 国家任务, 2022-01--2026-12
（ 4 ） 结构指导的免疫原设计及广谱保护机制研究, 参与, 国家任务, 2020-01--2024-12
（ 5 ） 国科大杭高院引进人才项目启动经费, 负责人, 研究所自主部署, 2023-05--2025-12
（ 6 ） 非激活态趋化素-趋化因子样受体CMKLR1的结构和功 能研究, 负责人, 地方任务, 2024-01--2026-12