General

Name: Wei

Family name: Ha

Nationality: P. R. China

Professional Title: Professor

Date and place of birth: 16/09/1984, Yinchuan, P. R. China

Email: hawei2012@licp.cas.cn


Research Areas

1. New materials and methods for intelligent drug loading and release 

2. New materials and methods for the separation and analysis of active ingredients in natural medicines


Education

Ph. D in Organic Chemistry and Supramolecular Chemistry, Lanzhou University, 2011.

BSc in Chemisrty, Lanzhou University, 2006.


Experience

2012-now, CAS Key Laboratory of Chemistry of Northwestern Plant Resources, Lanzhou Institute of Chemical Physics, CAS, Lanzhou, P. R. China

2011-2012, Natural Products research center, Chengdu Institute of Biology, CAS, Chengdu, P.R. China


Publications

   
Papers

1. Rui, Ma, Bakhrom Komilov, Cheng-Bo Wang, Komila Alibekovna Eshbakova, Jun-Li Yang, Wei Ha*, Yan-Ping Shi, Sesquiterpenes from Inula macrophylla and their anti-neuroinflammatory activity, Phytochemistry Letters, 2024, 60, 257-263.

2.Xiao-Kang Fu, Si-Qi Han, Wei Ha*, Yan-Ping Shi, Click Chemoselective Probe with a Photoswitchable Handle for Highly Sensitive Determination of Steroid Hormones in Food Samples, J. Agric. Food Chem. 2023, 71, 14814−14824.

3.Wei Ha, Jun-Li Yang, Yan-Ping Shi, Tannic Acid-Modified Silver Nanoparticles for Antibacterial and Anticancer Applications, ACS Appl. Nano Mater. 2023, 6, 9617−9627.

4.Xiao-Kang Fu, Hao-Bo Cao, Yu-Long An, Hui-Di Zhou, Yan-Ping Shi, Guo-Liang Hou,* and Wei Ha*Bioinspired Hydroxyapatite Coating Infiltrated with a Graphene Oxide Hybrid Supramolecular Hydrogel Orchestrates Antibacterialand Self-Lubricating Performance, ACS Appl. Mater. Interfaces 2022, 14, 31702−31714.

5.Wei Ha, Jun-Li Yang, Yan-Ping Shi, Antibacterial metal-phenolic nanosheets as smart carriers for the controlled release of epirubicin hydrochloride, Nanoscale, 2022, 14, 9806–9817.

6.Wei Ha, Guo-Liang Hou, Wu-Jun Qin, Xiao-Kang Fu, Xiao-Qin Zhao, Xiao-Dong Wei, Yu-Long An and Yan-Ping ShiSupramolecular hydrogel-infiltrated ceramics composite coating with combined antibacterial and self-lubricating performance, J. Mater. Chem. B, 2021, 9, 9852–9862.

7.Wei Ha, Xiao-Bo Zhao, Wei-Hua Zhao, Jiang-Jiang Tangb and Yan-Ping ShiA colon-targeted podophyllotoxin nanoprodrug: synthesis, characterization, and supramolecularhydrogel formation for the drug combinationJ. Mater. Chem. B, 2021, 9, 3200–3209.

8.Xin-Yue Chen, Wei Ha,* Xiao-Jie Jin and Yan-Ping Shi*, PEGylated NALC-functionalized gold nanoparticles for colorimetric discrimination of chiral tyrosine, Analyst, 2020, 145, 7397–7405.

9.Wei Ha, Ze-Hao Wang, Xiao-Bo Zhao, and Yan-Ping Shi*, Reinforced Supramolecular Hydrogels from Attapulgite and Cyclodextrin Pseudopolyrotaxane for Sustained Intra-Articular Drug Delivery, Macromolecular. Bioscience. 2021, 212000299.

10.Xiao-bo Zhao#, Wei Ha#, Kun Gao, Yan-ping Shi, Precisely traceable drug delivery of azoreductase-responsive prodrug for colon Targeting via multimodal imaging, Analytical Chemistry, 2020, 92, 9039-9047.

11. Xin-yue Chen, Wei Ha*, Yan-ping Shi*, Sensitive colorimetric detection of melamine in processed raw milk using asymmetrically PEGylated gold nanoparticles, Talanta, 2019, 194, 475-484.

12.   Xin-yue Chen, Run-tian Ma, Wei Ha*, Yan-ping Shi*, Direct colorimetric detection of aspartic acid in rat brain based on oriented aggregation of Janus gold nanoparticle, Sensors & Actuators: B. Chemical, 2018, 274, 668–675.

13.Wei Ha, Xiao-bo Zhao, Xin-yue Chen, Kan Jiang, and Yan-ping Shi, Prodrug-Based Cascade Self-Assembly Strategy for Precisely Controlled Combination Drug Therapy, ACS Appl. Mater. Interfaces 2018, 10, 21149−21159.

14.  Xiao-Bo Zhao#, Wei Ha#,  Kan Jiang, Juan Chen, Jun-Li Yang, Yan-Ping Shi*, Efficient synthesis of camptothecin propargylamine derivatives in water catalyzed by macroporous adsorption resin-supported gold nanoparticles, Green Chemistry, 2017, 19, 1399-1406.

15.  Wei Ha, Xiaobo Zhao, Kan Jiang, Yang Kang, Juan Chen, Bang-Jing Li*, Yan-Ping Shi*, A three-dimensional graphene oxide supramolecular hydrogel for infrared light-responsive cascade release of two anticancer drugs, Chemical Communications, 2016, 52, 14384-14387.

16. Wei Ha, Jing Yu, Juan Chen, Yan-Ping Shi*, 3D graphene oxide supramolecular hybrid hydrogel with well-ordered interior microstructure prepared by a host-guest inclusion-induced self-assembly strategy, RSC Advances, 2016, 6, 94723-94730.

17.  Wei Ha, Xin-yue Song, Juan Chen, Yan-ping Shi, A physical entrapment method for the preparation of carbon nanotube reinforced macroporous adsorption resin with enhanced selective extraction performance, Nanoscale, 2015, 7, 18619-18627.

18.Wei Ha, Jing Yu, Xin-Yue Song, Juan Chen, Yan-Ping Shi*, Tunable temperature-responsive supramolecular hydrogels formed by prodrugs as a codelivery system, ACS Applied Materials & Interfaces, 2014, 6, 10623-10630.

19. Wei Ha, Jing Yu, Rui Wang, Juan Chen, Yan-Ping Shi*, Green colorimetric assay for the selective detection of trivalent chromium based on Xanthoceras sorbifolia tannin attached to gold nanoparticles, Analytical Methods, 2014, 6, 5720-5726.

20.  Wei Ha, Jing Yu, Xin-Yue Song, Zhi-Jun Zhang, Ying-Qian Liu, Yan-Ping Shi*, Prodrugs forming multifunctional supramolecular hydrogels for dual cancer drug delivery, Journal of Materials Chemistry B, 2013, 1, 5532.

21.  Wei Ha, Yang Kang, Shu-Lin Peng, Li-Sheng Ding, Sheng Zhang*, Bang-Jing Li*, Vesicular gold assemblies based on host-guest inclusion and its controllable release of doxorubicin, Nanotechnology, 2013, 24, 495103-495110.

22.  Wei Ha, Hao Wu, Yuan Ma, Min-Min Fan, Shu-Lin Peng, Li-Sheng Ding, Sheng Zhang*, Bang-Jing Li*, Synthesis of biocompatible hybrid magnetic hollow spheres based on encapsulation strategy,, Carbohydrate Polymers, 2013, 92, 523-528.

23.Wei Ha, et al., Journal of controlled release, 2011, 152, supplement 1, e204-e205.

24.  Wei Ha, Xian-Wei Meng, Quan Li, Min-Min Fan, Shu-Lin Peng, Li-Sheng Ding, Xuan Tian, Sheng Zhang*, Bang-Jing Li*, Encapsulation studies and selective membrane permeability properties of self-assembly hollow nanospheres, Soft Matter Invited Paper, 2011, 7, 1018–1024.

25. Wei Ha, Hao Wu, Xiao-Ling Wang, Shu-Lin Peng, Li-Sheng Ding, Sheng Zhang*, Bang-Jing Li*, Self-aggregates of cholesterol-modified carboxymethyl konjac glucomannan conjugate: Preparation, characterization, and preliminary assessment as a carrier of etoposide, Carbohydrate Polymers, 2011, 86, 513-519.

26.Wei Ha, Xian-Wei Meng, Quan Li, Min-Min Fan, Shu-Lin Peng, Li-Sheng Ding, Xuan Tian, Sheng Zhang*, Bang-Jing Li*, Self-assembly hollow nanosphere for enzyme encapsulation, Soft Matter 2010, 6, 1405-1408. (RSC Highlights in Chemical Biology)