1. 病毒核酸表观遗传学: 利用组学技术结合病毒学方法分析RNA修饰如m6A、m5C和ac4C等对病毒基因组复制、RNA加工和翻译的影响，揭示RNA修饰系统与病毒关键蛋白相互作用的分子机制；

2. 新发高致病性病原生物学: 以尼帕病毒、埃博拉病毒和克里米亚-刚果出血热病毒等BSL-4病原为对象，探索高致病性病毒与宿主的相互作用、筛选相应的分子靶标和抗病毒药物。

071010-生物化学与分子生物学

病毒表观遗传学
新发烈性传染病病毒分子生物学

2003-09--2006-07   中国疾病预防控制中心病毒病所   医学博士
2000-09--2003-07   华中科技大学同济医学院   医学硕士
1995-09--2000-07   华中科技大学同济医学院   医学本科

   

2022-10~现在, 中国科学院武汉分院, 副院长
2018-10~2022-09,中国科学院武汉病毒研究所, 副所长
2017-08~2018-10,中国科学院武汉病毒研究所, 所长助理
2012-06~2017-07,中国科学院武汉病毒研究所, 学科组长

2024-07-01-今,湖北中医药大学药学院教授, 教授
2022-09-01-今,湖北江夏实验室, 实验室主任
2021-12-30-2027-12-30,生物安全重点研发计划, 指南专家
2020-12-31-2026-12-30,科技部传染病重大专项, 指南专家
2019-11-01-今,中华医学会医学病毒分会, 常务委员
2018-12-01-2023-12-30,武汉微生物学会, 常务理事
2017-09-30-2019-09-30,EBS 杂志, 编委

分子生物学

   

（1） 全国科技系统抗击新冠疫情“先进集体”, 特等奖, 国家级, 2021
（2） 中科院武汉病毒所年度优秀共产党员, 特等奖, 研究所（学校）, 2016

[1] 关武祥, 解举民. 一种核糖核酸酶及其衍生物和/或变体及其应用. CN: CN106244570A, 2016-12-21.

[2] 关武祥, 张雪艳, 黄方, 陈珍. 一种ac4C乙酰化修饰调控RNA剪接的方法. CN: CN117887811A, 2024-04-16.

[3] 关武祥, 朱妙, 黄方, 孙慧泽, 余宝成, 刘鲲鹏, 陈珍. 一种防治新型冠状病毒的药物及其应用. CN: CN118078827A, 2024-05-28.

[4] 关武祥, 朱妙, 黄方, 孙慧泽, 余宝成, 刘鲲鹏, 陈珍. 去甲乌药碱在防治新型冠状病毒中的应用. CN: CN118121605A, 2024-06-04.

   

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（ 1 ） 高致病性病毒感染及致病机制, 负责人, 中国科学院计划, 2023-01--2027-12
（ 2 ） 艾美Ⅱ期mRNA疫苗临床试验, 负责人, 其他, 2022-01--2023-12
（ 3 ） 重要呼吸道传播病原感染致病机制及药物靶点开发, 负责人, 地方任务, 2022-01--2023-12
（ 4 ） 新冠疫苗体液免疫评价, 负责人, 地方任务, 2021-08--2022-06
（ 5 ） 重组新型冠状病毒融合蛋白疫苗免疫原性研究, 负责人, 境内委托项目, 2021-01--2023-12
（ 6 ） 生物关键创新技术, 负责人, 中国科学院计划, 2021-01--2023-12
（ 7 ） 我国与重要疫源地国家一类病原资源发掘及风险控制研究, 负责人, 其他国际合作项目, 2021-01--2023-12
（ 8 ） 新冠肺炎病人排毒规律与新冠病毒环境耐受性研究, 参与, 国家任务, 2020-01--2021-12
（ 9 ） 变异新冠病毒预警及风险评估体系建设, 负责人, 地方任务, 2020-01--2022-12
（ 10 ） m6A修饰调控免疫应答及病毒复制的分子机制, 负责人, 国家任务, 2020-01--2021-12
（ 11 ） 新型冠状病毒感染的肺炎疫情环境风险防控, 参与, 国家任务, 2020-01--2021-01
（ 12 ） 新型冠状病毒感染不同进程与宿主的相互作用研究, 负责人, 国家任务, 2020-01--2021-06
（ 13 ） 创新技术, 负责人, 中国科学院计划, 2019-07--2022-06
（ 14 ） 新发烈性传染病应急防控能力建设, 负责人, 国家任务, 2019-01--2024-12
（ 15 ） 重要新发突发病毒宿主适应与损伤机制研究, 负责人, 国家任务, 2016-07--2018-12
（ 16 ） 各种假病毒和复制子的构建, 负责人, 国家任务, 2015-07--2017-12
（ 17 ） 基因组, 负责人, 中国科学院计划, 2015-06--2016-06
（ 18 ） SFTS病毒基因组甲基化, 负责人, 中国科学院计划, 2015-01--2016-12
（ 19 ） 病毒资源和复制体系, 参与, 中国科学院计划, 2015-01--2018-12
（ 20 ） 细小病毒B19polyA选择性使用机制, 负责人, 中国科学院计划, 2014-01--2016-12
（ 21 ） 细小病毒B19polyA选择性使用机制, 负责人, 国家任务, 2013-01--2016-12
（ 22 ） 细小病毒转录及转录后调控研究, 负责人, 研究所自主部署, 2012-06--2013-12

已指导学生

郝素娟  博士研究生  071010-生物化学与分子生物学  

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潘超虎  硕士研究生  071010-生物化学与分子生物学  

张军梅  博士研究生  071010-生物化学与分子生物学  

郝好杰  博士研究生  071010-生物化学与分子生物学  

胡潇  博士研究生  071010-生物化学与分子生物学  

张业成  博士研究生  071010-生物化学与分子生物学  

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现指导学生

孙慧泽  博士研究生  071010-生物化学与分子生物学  

张雨迪  博士研究生  071010-生物化学与分子生物学  

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郭祥  博士研究生  071010-生物化学与分子生物学  

罗婷  硕士研究生  071005-微生物学  

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田梦鸽  硕士研究生  071010-生物化学与分子生物学  

黄燕玲  硕士研究生  100102-免疫学