马光辉 女 汉族 博导 过程工程研究所
Email: ghma@ipe.ac.cn
Telephone: 010-82627072
Address: 北京市海淀区中关村北二街1号
Postcode: 100190
Research Areas
Preparation of microspheres and microcapsules with uniform sizes and controllable structures for bioseparation and drug delivery carriers
Education
1984-1988 | Gunma University | Bachelor |
1988-1990 | Tokyo Institute of Technology | Master |
1990-1993 | Tokyo Institute of Technology | Ph. D |
Experience
Work Experience
1994-2001 | Tokyo University of Agriculture and Technology-Assistant Professor |
2001-now | Institute of Process Engineering, Chinese Academy of Sciences- Professor |
2005-2013 | Deputy Director of Institute of Process Engineering, CAS |
2002-2011 | Deputy Director of State Key Laboratory of Biochemical Engineering |
2012-now | Director of State Key Laboratory of Biochemical Engineering |
Honors & Distinctions
2001 | The National Science Fund for Distinguished Young Scholars |
2005 | First-class prize of Beijing Science and Technology Award (rank the first) |
2005 | The 2nd "Top Ten Women" of the Chinese Academy of Sciences |
2006 | Original Research Top Citation Award (Elsevier Issued) |
2008 | The 4th Women Inventor of the New Century (first of ten) |
2008 | The 10th China International High-tech "Outstanding Achievements Conversion Project Award" (rank the first) |
2009 | Second-class prize of National Invention Award (First prize winner) |
2009 | Third World Academy of Sciences - Third World Women's Science Organization - Elsevier Young Women Researchers (rank the first) |
2010 | 2006-2010 Top 50 of Chinese Authors Citation Awards (Elsevier Issued) |
2010 | First-class prize of China Petroleum and Chemical Industry Excellent Publication Award |
2011 | Chinese Instrument and Meter Association Science and Technology Award - Science and Technology Innovation Award (rank the second) |
2012 | Asian Biotechnology Association Outstanding Contribution Award (rank the first) |
2013 | First-class prize of China Association for Analysis and Testing Science and Technology Award (rank the second) |
2013 | First-class prize of China Petroleum and Chemical Industry Federation Technical Invention Award (rank the second) |
2014 | Second-class prize of China Association for Analysis and Testing Science and Technology Award (rank the second) |
2014 | China Chemical Industry Association "Hou Debang Chemical Technology Innovation Award" (rank the first) |
2016 | China Association for Science and Technology, National outstanding science and technology workers |
Publications
Papers
2019
1. Pengyu Chen#, Hua Yue#, Xiaobo Zhai, Zihan Huang, Guanghui Ma, Wie Wei*, Litang Yan*. Transport of a graphene nanosheet sandwiched inside cell membranes. Sci. Adv. 5 (2019) eaaw3192.
2. Shuang Wang#, Jiang-Hua Wang#, Wei Wei*, GuangHui Ma*. Exosomes: the indispensable messenger in tumor pathogenesis and the rising star in anti-tumor applications. Adv. Biosys. 2019 DOI: 10.1002/adbi. 201900008.
3. Xun Li, Yi Wei*, Piping Lv, Youbin Wu, Kenji Ogino, Guanghui Ma*. Preparation of ropivacaine loaded PLGA microspheres as controlled-release system with narrow size distribution and high loading efficiency. Colloid. Surface. A 562(2019) 237-246.
4. Xiangming Na, Weiqing Zhou, Tong Li, Ding Hong, Juan Lia, Guanghui Ma∗. Preparation of double-emulsion-templated microspheres withcontrollable porous structures by premix membrane emulsification. Particuology 2019 DOI: 10.1016/j.partic.2018.07.007
5. Jie Wu, Guanghui Ma*. Imitation of nature: Bionic design in the study of particle adjuvants. J. Control. Release 303(2019) 101-108.
6. Lijun Zhang, Xiao Zhang, Guihong Lu, Feng Li, Weier Bao, Cui Song, Wei Wei*, Guanghui Ma*. Cell Membrane Camouflaged Hydrophobic Drug Nanoflake Sandwiched with Photosensitizer for Orchestration of Chemo-Photothermal Combination Therapy. Small 15 (2019) 1805544.
7. Feng Qi*, Jie Wu, Hao Li, Guanghui Ma*. Recent research and development of PLGA/PLA microspheres/nanoparticles: A review in scientific and industrial aspects. Front. Chem. Sci. Eng. 13 (2019) 14-27.
8. Yiqun Du#, Yufei Xia#, Yongjuan Zou, Yuning Hu, Jiaqi Fu, Jie Wu*, Xiaodong Gao*, Guanghui Ma*. Exploiting the Lymph-Node-Amplifying Effect for Potent Systemic and Gastrointestinal Immune Responses via Polymer/Lipid Nanoparticles. ACS Nano 13(2019), 13809-13817.
9. Cui Song#, Feng Li#, Shuang Wang, Jianghua Wang, Wei Wei*, Guanghui Ma*. Recent advances in particulate adjuvants for cancer vaccination. Adv. Ther. (2019) 1900115.
10. Zonglin Gu#, Serena H. Chen#, Zhaowen Ding, Wei Song, Wei Wei, Shengtang Liu, Guanghui Ma*, Ruhong Zhou*. The molecular mechanism of robust macrophage immune responses induced by PEGylated molybdenum disulfide? Nanoscale 11(2019) 22293-22304.
11. Weiying Wang, Dongxia Hao, Jia Ge, Lan Zhao, Yongdong Huang, Kai Zhu, Xvexing Wu, Zhiguo Su, Rong Yu*, Guanghui Ma*. A minimalist peptide ligand for IgG by minimizing the binding domain of protein A. Biochem. Eng. J. 151(2019).
12. Xi Zhao#, Lan Huang#, Jie Wu*, Yongdong Huang, Lan Zhao, Nan Wu, Weiqing Zhou, Dongxia Hao, Guanghui Ma*, Zhiguo Su. Fabrication of rigid and macroporous agarose microspheres by pre-cross-linking and surfactant micelles swelling method. Colloid. Surface. B 182(2019) 110377.
13. Mingzhu Ding, Biqiang Chen, Xiaojun Ji, Jingwen Zhou, Huiyuan Wang, Xiwei Tian, Xudong Feng, Hua Yue, Yongjin Zhou, Hailong Wang, Jianping Wu, Pengpeng Yang, Yu Jiang, Xuming Mao, Gang Xiao, Cheng Zhong, Wenhai Xiao, Bingzhi Li, Lei Qin, Jingsheng Cheng, Mingdong Yao, Ying Wang, Hong Liu, Lin Zhang, Linling Yu, Tao Chen, Xiaoyan Dong, Xiaoqiang Jia, Songping Zhang, Yanfeng Liu, Yong Chen, Kequan Chen, Jinglan Wu, Chenjie Zhu, Wei Zhuang, Sheng Xu, Pengfei Jiao, Lei Zhang, Hao Song, Sheng Yang, Yan Xiong, Yongquan Li, Youming Zhang, Yingping Zhuang, Haijia Su, Weiping Fu, Yingming Huang, Chun Li, Zongbao K. Zhao, Yan Sun, Guo-Qiang Chen, Xueming Zhao, He Huang, Yuguo Zheng, Lirong Yang, Zhiguo Su, Guanghui Ma, Hanjie Ying, Jian Chen, Tianwei Tan, Yingjin Yuan*. Biochemical engineering in China. Rev. Chem. Eng. 35(2019) 929-993.
14. Shu Kikuchi, Saki Yoshida, Shinji Kanehashi*, Guanghui Ma, Kenji Ogino*. Fabrication of Core-Shell, Janus, Dumbbell, Snowman-Like and Confetti-Like Structured Microspheres of Blends of Poly(4-butyl triphenylamine) and Poly (methyl methacrylate) by Solvent Evaporation Method. J. Fiber Sci. Technol. 75(2019) 22-28.
15. Lingling Xu, Zhengjun Li, Zhiguo Su, Yanli Yang, Guanghui Ma, Rong Yu*, Songping Zhang*. Development of meningococcal polysaccharide conjugate vaccine that can elicit long-lasting and strong cellular immune response with hepatitis B core antigen virus-like particles as a novel carrier protein. Vaccine 37(2019) 956-964.
2018
16. Yufei Xia#, Jie Wu#, Wei Wei, Yiqun Du, Tao Wan, Xiaowei Ma, Wenqi An, Aiying Guo,Chunyu Miao, Hua Yue, Shuoguo Li, Xuetao Cao, Zhiguo Su*, Guanghui Ma*. Exploiting the pliability and lateral mobility of Pickering emulsion for enhanced vaccination. Nat. Mater. 17(2018)187-193.
17. Yufei Xia#, Xiangming Na#, Jie Wu, Guanghui Ma*. The horizon of emulsion particulate strategy: Engineering hollow particles for biomedical applications. Adv. Mater. (2018) 1801159.
18. Yufei Xia#, Jie Wu#, Yiqun Du, Chunyu Miao, Zhiguo Su*, Guanghui Ma*. Bridging systemic immunity with gastrointestinal immune responses via oil-in-polymer capsules. Adv. Mater. 30(2018) 1801067.
19. Yanlin Lv, Ming Liu, Yong Zhang*, Xuefei Wang, Fan Zhang, Feng Li, Wei-Er Bao, Jie Wang, Yuanlin Zhang, Wei Wei*, Guanghui Ma*, Liancheng Zhao, Zhiyuan Tian*. Cancer cell membrane-biomimetic nanoprobes with two-photon excitation and near-infrared emission for intravital tumor fluorescence imaging, ACS Nano 12(2018) 1350-1358.
20. Shuang Wang, Dezhi Ni, Hua Yue, Nana Luo, Xiaobo Xi, Yugang Wang, Min Shi, Wei Wei*, Guanghui Ma*. Exploration of antigen induced CaCO3 nanoparticles for therapeutic vaccine. Small 14(2018) 1704272.
21. Hua Yue#, Lan Yuan#, Weiwei Zhang, Shujia Zhang, Wei Wei*, Guanghui Ma*. Macrophage responses to the physical burden of cell-sized particles. J. Mater. Chem. B 6(2018) 393-400.
22. Xiao Zhang#, Cui Song#, Guanghui Ma*, Wei Wei*. Mechanical determination of particle-cell interactions and the associated biomedical applications. J. Mater. Chem. B 6(2018) 7129-7143.
23. Xiaobo Xi, Lijun Zhang, Guihong Lu, Xiaoyong Gao, Wei Wei*, Guanghui Ma*. Lymph node-targeting nanovaccine through antigen-CpG self-assembly potentiates cytotoxic T cell activation. J. Immunol. Res. (2018) 3714960.
24. Sihua Wu#, Hua Yue#, Jie Wu, Wenming Zhang, Min Jiang*, Guanghui Ma*. The interacting role of physical stiffness and tumor cells on the macrophages polarization. Colloid. Surface. A 552(2018) 81-88.
25. Feng Qi, Jie Wu, Hao Li, Guanghui Ma*. Recent research and development of PLGA/PLA microspheres/nanoparticles: A review in scientific and industrial aspects. Front. Chem. Sci. Eng. (2018) 1-14.
26. Lan Zhao#,*, Wei Wei#, Yongdong Huang, Rongyue Zhang, Kai Zhu, Dongxia Hao, Zhiguo Su, Guanghui Ma*. A novel rProtein A chromatographic media for enhancing cleaning-in-place performance. J. Immunol. Methods 460(2018) 45-50.
27. Hongwu Zhang, Lan Zhao*, Yongdong Huang, Kai Zhu, Qibao Wang, Rui Yang, Zhiguo Su, Guanghui Ma*. Uniform polysaccharide composite microspheres with controllable network by microporous membrane emulsification technique. Anal. Bioanal. Chem. 410(2018) 4331-4341.
28. Han Zhang, Kai Liu, Shukun Li, Xia Xin*, Shiling Yuan*, Guanghui Ma, Xuehai Yan*. Self-assembled minimalist multifunctional theranostic nanoplatform for magnetic resonance imaging-guided tumor photodynamic therapy. ACS Nano 12(2018) 8266-8276.
29. Libing Mu, Zhongyuan Tu, Lin Miao, Hefei Ruan, Ning Kang, Yongzhen Hei, Jiahuan Chen, Wei Wei, Fangling Gong, Bingjie Wang, Yanan Du, Guanghui Ma, Matthias W. Amerein, Tie Xia*, Yan Shi*. A phosphatidylinositol 4,5-bisphosphate redistribution-based sensing mechanism initiates a phagocytosis programing. Nat. Commun. 9(2018) 4259.
30. Yan Li, Yanhui Li, Weihong Ji, Zhiguo Lu, Linying Liu, Yuanjie Shi, Guanghui Ma, Xin Zhang*. Positively charged polyprodrug amphiphiles with enhanced drug loading and reactive oxygen species-responsive release ability for traceable synergistic therapy. J. Am. Chem. Soc. 140(2018) 4164–4171.
31. Fan Zhang, Longjian Zhao, Shumin Wang, Jun Yang, Guihong Lu, Nana Luo, Xiaoyong Gao, Guanghui Ma, HaiYan Xie*, Wei Wei*. Construction of a biomimetic magnetosome and its application as a SiRNA carrier for high-performance anticancer therapy. Adv. Funct. Mater. 28(2018) 1703326.
32. Xiaoyuan Ji#, Jie Wang#, Lin Mei, Wei Tao, Austin Barrett, Zhiguo Su, Shaomin Wang, Guanghui Ma, Jinjun Shi*, Songping Zhang*. Porphyrin/SiO2/Cp*Rh(bpy)Cl hybrid nanoparticles mimicking chloroplast with enhanced eectronic energy transfer for biocatalyzed artificial photosynthesis. Adv. Funct. Mater. 28(2018) 1705083.
33. Xiaoyuan Ji, Jie Wang, Yong Kang, Lin Mei*, Zhiguo Su, Shaomin Wang, Guanghui Ma, Jinjun Shi*, Songping Zhang*. Enhanced solar energy harvest and electron transfer through intra- and intermolecular dual channels in chlorosome-mimicking supramolecular self-assemblies. ACS Catal. 8(2018) 10732-10745.
34. Xiaoyuan Ji, Yong Kang, Zhiguo Su, Ping Wang, Guanghui Ma, Songping Zhang*. A Graphene Oxide and Polyelectrolyte Composed One-Way Expressway for Guiding Electron Transfer of Integrated Artificial Photosynthesis. ACS Sustain. Chem. Eng. 6(2018) 3060-3069.
35. Zhengjun Li, Jiangxue Wei, Yanli Yang, Lili Liu, Guanghui Ma, Songping Zhang*, ZhiguoSu*. A two-step heat treatment of cell disruption supernatant enables efficient removal of host cell proteins before chromatographic purification of HBc particles. J. Chromatogr. A 1581-1582(2018) 71-79.
36. Zhengjun Li, Jiangxue Wei, Yanli Yang, Xiaowei Ma, Baidong Hou, Wenqi An, Zhaolin Hua, Jingjing Zhang, Yao Li, Guanghui Ma, Songping Zhang*, ZhiguoSu*. Strong hydrophobicity enables efficient purification of HBc VLPs displaying various antigen epitopes through hydrophobic interaction chromatography. Biochem. Eng. J. 140(2018) 157-167.
37. Xiaoyuan Ji, Zhiguo Su, Guanghui Ma, Songping Zhang*. Sandwiching multiple dehydrogenases and shared cofactor between double polyelectrolytes for enhanced communication of cofactor and enzymes. Biochem. Eng. J. 137(2018) 40-49.
2017
38. Nana Luo#, Jeffrey K. Weber#, Shuang Wang, Binquan Luan, Hua Yue, Xiaobo Xi, Jing Du, Zaixing Yang, Wei Wei*, Ruhong Zhou*, Guanghui Ma*. PEGylated graphene oxide elicits strong immunological responses despite surface passivation. Nat. Commun. 8 (2017) 14537.
39. Dezhi Ni#, Shuang Qing#, Hui Ding, Hua Yue, Di Yu, Shuang Wang, Nana Luo, Zhiguo Su, Wei Wei*, Guanghui Ma*. Biomimetically engineered demi-bacteria potentiate vaccination against cancer. Adv. Sci. 4(2017) 1700083.
40. Hui Ding, Fan Zhang, Chaochao Zhao, Yanlin Lv, Guanghui Ma*, Wei Wei*, Zhiyuan Tian*. Beyond a Carrier: Graphene Quantum Dots as a Probe for Programmatically Monitoring Anti-Cancer Drug Delivery, Release, and Response. ACS Appl. Mater. Interfaces 9(2017) 27396-27401.
41. Jilei Jia, Qi Liu, Tingyuan Yang, Lianyan Wang*, Guanghui Ma*. Facile fabrication of varisized calcium carbonate microspheres as vaccine adjuvants. J. Mater. Chem. B. 5(2017) 1611-1623.
42. Jilei Jia#, Weifeng Zhang#, Qi Liu, Tingyuan Yang, Lianyan Wang*, Guanghui Ma*. Adjuvanticity regulation by biodegradable polymeric nano/microparticle size. Mol. Pharmaceut. 14(2017) 14-22.
43. Enping Lai, Yuxia Wang*, Yi Wei, Guang Li, Guanghui Ma*. Effects of cross-link density on structures and properties of dual-sensitive semi-interpenetrating polymer networks hydrogel microspheres. Macromol. Chem. Phys. 218(2017) 1-10.
44. Lan Zhao#, Kai Zhu#, Yongdong Huang*, Qiang Li, Xiunan Li, Rongyue Zhang, Zhiguo Su, Qibao Wang, Guanghui Ma*. Enhanced binding by dextran-grafting to Protein A affinity
chromatographic media. J. Sep. Sci. 40(2017) 1493-1499.
45. Qianmei Zhang#, Wei Wei#, Peilin Wang, Liping Zuo, Feng Li, Jin Xu, Xiaobo Xi, Xiaoyong Gao, Guanghui Ma, Hai-yan Xie*. Biomimetic Magnetosomes as Versatile Artificial Antigen-Presenting Cells to Potentiate T-Cell-Based Anticancer Therapy. ACS Nano 11(2017) 10724-10732.
46. Xiaoyuan Ji, Cuicui Liu, Jie Wang, Zhiguo Su, Guanghui Ma, Songping Zhang*. Integration of functionalized two-dimensional TaS2 nanosheets and an electron mediator for more efficient biocatalyzed artificial photosynthesis. J. Mater. Chem. A 5(2017) 5511-5522.
47. Luyang Zhao, Guizhi Shen, Guanghui Ma, XuehaiYan*. Engineering and delivery of nanocolloids of hydrophobic drugs. Adv. Colloid Interface Sci. 249(2017) 308-320.
48. Zenghui Chen, Songping Zhang*, Zhengjun Li, Guanghui Ma, Zhiguo Su*. Construction of a stable w/o nano-emulsion as a potential adjuvant for foot and mouth disease virus vaccine. Artif. Cell. Nanomed. Biotech. 45(2017) 897-906.
49. Yanli Yang, Qizu Zhao, Zhengjun Li, Lijing Sun, Guanghui Ma, Songping Zhang*, Zhiguo Su*. Stabilization study of inactivated foot and mouth disease virus vaccine by size-exclusion HPLC and differential scanning calorimetry. Vaccine 35(2017) 2413-2419.
50. Zenglan Li, Chun Zhang, Yan Zhang, Yongdong Liu, Xiunan Li, Guanghui Ma, Jian Luo*, Zhiguo Su*. Prevention of aggregate formation through mechanism analysis in refolding of recombinant pertactin from Escherichia coli. Process Biochem. 62(2017) 80-90.
51. Shanqin Liang#, Yanli Yang#, Lijing Sun, Qizu Zhao, Guanghui Ma, Songping Zhang*, Zhiguo Su*. Denaturation of inactivated FMDV in ion exchange chromatography: Evidence by differential scanning calorimetry analysis. Biochem. Eng. J. 124(2017) 99-107.
52. Kun Zhang#, Qiang Li#,*, Hong Fan, Suning Li, Yue Su, Lan Zhao, Yongdong Huang, Dan Wang, Zhigang Zhang*, Zhiguo Su, Guanghui Ma. Multi-layer dextran-decorated poly(glycidyl methacrylate)-co-divinyl benzene copolymer matrices enabling efficient protein chromatographic separation. React. Funct. Polym. 112(2017) 45-52.
53. Chao Chen#, Xiunan Li#,*, Dawei Zhao, Yaqiong Li, Hong Shi, Guanghui Ma, Zhiguo Su. Precise control of agarose media pore structure by regulating cooling rate. J. Sep. Sci. 40(2017) 4467-4474.
54. Yaqiong Li#, Xiunan Li#,*, Chao Chen, Dawei Zhao, Zhiguo Su, Guanghui Ma, Rong Yu*. Sol-gel transition characterization of thermosensitive hydrogels based on water mobility variation provided by low field NMR. J. Polym. Res. 24(2017) 25.
2016
55. Jie Wu, Guanghui Ma*. Recent studies of Pickering emulsions: Particles make the difference. Small 12(2016) 4633-4648.
56. Qi Liu, Jilei Jia, Tingyuan Yang, Qingze Fan, Lianyan Wang*, Guanghui Ma*. Pathogen-mimicking polymeric nanoparticles based on dopamine polymerization as vaccines adjuvants induce robust humoral and cellular immune responses. Small 12(2016) 1744-1757.
57. Qiang Li*, Rongyue Zhang, Dexi Wu, Yongdong Huang, Lan Zhao, Dan Wang, Fangling Gong, Liang Li, Han Qiu, Guanghui Ma*. Cell-nanoparticle assembly fabricated for CO2 capture and in situ carbon conversion. J. CO2 Util. 13(2016) 17-23.
58. Shan Liu#, Wei Wei#, Bo Xie, Hua Yue, Dezhi Ni, Yali Bao, Guanghui Ma*, Zhiguo Su*. Breaching the hyaluronan barrier with PH20-Fc facilitates intratumoral permeation and enhances antitumor efficiency: A comparative investigation of typical therapeutic agents in different nanoscales. Adv. Healthc. Mater. 5(2016) 2872-2881.
59. Yue-Qi Wang#, Qing-Ze Fan#, Yan Liu, Hua Yue, Xiao-Wei Ma, Jie Wu*, Guang-Hui Ma*, Zhi-Guo Su. Improving adjuvanticity of quaternized chitosan–based microgels for H5N1 split vaccine by tailoring the particle properties to achieve antigen dose sparing effect. Int. J. Pharmaceut. 515(2016) 84-93.
60. Wei Wei#, Dan Zhu#, Zhenhua Wang, Dezhi Ni, Hua Yue, Shuang Wang, Yong Tao*, Guanghui Ma*. Positively charged armed nanoparticles demonstrate their precise delivery performance for effective treatment of chorioretinal diseases. J. Mater. Chem. B. 4(2016) 2548-2552.
61. Dongxia Hao, Jia Ge, Yongdong Huang, Lan Zhao, Guanghui Ma*, Zhiguo Su*. Microscopic insight into role of protein flexibility during ion exchange chromatography by nuclear magnetic resonance and quartz crystal microbalance approaches. J. Chromatogr. A 1438(2016) 65-75.
62. Weichen Wang, Weiqing Zhou, Wei Wei, Juan Li, Dongxia Hao, Zhiguo Su, Guanghui Ma*. Towards a deeper understanding of the interfacial adsorption of enzyme molecules in gigaporous polymeric microspheres. Polymers 8(2016) 116-125.
63. Donglai Zhang, Weiqing Zhou, Juan Li, Yace Mi, Zhiguo Su, Guanghui Ma*. The construction of an aqueous two-phase system to solve weak-aggregation of gigaporous poly(styrene-divinyl Benzene) microspheres. Polymers 8(2016) 142-153.
64. Yace Mi#, Juan Li#, Weiqing Zhou, Rongyue Zhang, Guanghui Ma*, Zhiguo Su. Improved Stability of Emulsions in Preparation of Uniform Small-Sized Konjac Glucomanna (KGM) Microspheres with Epoxy-Based Polymer Membrane by Premix Membrane Emulsification. Polymers 8(2016) 53-65.
65. Yi Wei#, Yuxia Wang#, Huixia Zhang, Weiqing Zhou, Guanghui Ma*. A novel strategy for the preparation of porous microspheres and its application in peptide drug loading. J. Colloid Interf. Sci. 478(2016) 46-53.
66. Qingze Fan#, Feng Qi#, Chunyu Miao, Hua Yue, Fangling Gong, Jie Wu*, Guanghui Ma*, Zhiguo Su. Direct and controllable preparation of uniform PLGA particles with various shapes and surface morphologies. Colloid. Surface. A 500(2016) 177-185.
67. Yue-Qi Wang#, Yan Liu#, Yu-Xia Wang, Ya-Jun Wu, Pei-Yuan Jia, Jun-Jie Shan*, Jie Wu*, Guang-Hui Ma*, Zhi-Guo Su. The potential adjuvanticity of quaternized chitosan hydrogel based microparticles for porcine reproductive and respiratory syndrome virus inactivated vaccine. Int Immunopharmacol. 39(2016) 84-91.
68. Qiang Li*, Lan Zhao, Rongyue Zhang, Yongdong Huang, Yan Zhang, Kun Zhang, Xuexing Wu, Zhigang Zhang, Fangling Gong, Zhiguo Su, Guanghui Ma*. Functional hydrophilic polystyrene beads with uniformly size and high cross-linking degree facilitated rapid separation of exenatide. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 1017(2016) 129-135.
69. Lan Zhao#, Jingfei Zhang#, Yongdong Huang*, Qiang Li, Rongyue Zhang, Kai Zhu, Jia Suo, Zhiguo Su, Zhigang Zhang, Guanghui Ma*. Efficient fabrication of high-capacity immobilized metal ion affinity chromatographic media: The role of the dextran-grafting process and its manipulation. J. Sep. Sci. 39(2016) 1130-1136.
70. Ruirui Xing, Kai Liu, Tifeng Jiao*, Ning Zhang, Kai Ma, Ruiyun Zhang, Qianli Zou*, Guanghui Ma, Xuehai Yan*. An Injectable Self-Assembling Collagen-Gold Hybrid Hydrogel for Combinatorial Antitumor Photothermal/Photodynamic Therapy. Adv. Mater. 28(2016) 3669-3676.
71. Ke Xiong#, Wei Wei#, Yongjie Jin, Shumin Wang, Dongxu Zhao, Shuang Wang, Xiaoyong Gao, Chenmeng Qiao, Hua Yue, Guanghui Ma, Hai-Yan Xie*. Biomimetic Immuno-Magnetosomes for High-Performance Enrichment of Circulating Tumor Cells. Adv. Mater. 28(2016) 7929-7935.
72. Guizhi Shen, Ruirui Xing, Ning Zhang, Chengjun Chen, Guanghui Ma, Xuehai Yan*. Interfacial Cohesion and Assembly of Bioadhesive Molecules for Design of Long Term Stable Hydrophobic Nanodrugs toward Effective Anticancer Therapy. ACS Nano 10(2016) 5720-5729.
73. Kai Liu#, Ruirui Xing#, Qianli Zou, Guanghui Ma, Helmuth Mohwald, Xuehai Yan*. Simple Peptide-Tuned Self-Assembly of Photosensitizers towards Anticancer Photodynamic Therapy. Angew.Chem.Int. Ed. 55(2016) 3036-3039.
74. Yan Li, Ruilong Zhang, Zhiguo Su, Guanghui Ma, Lei Chen, Qunwei Tang*, Xin Zhang*. Microenvironment-Responsive Three-Pronged Approach Breaking Traditional Chemotherapy to Target Cancer Stem Cells for Synergistic Inoperable Large Tumor Therapy. Small 12(2016) 5516-5523.
75. Zhang, Ning, Fenfang Zhao, Qianli Zou, Yongxin Li, Guanghui Ma, Xuehai Yan*. Multitriggered Tumor-Responsive Drug Delivery Vehicles Based on Protein and Polypeptide Coassembly for Enhanced Photodynamic Tumor Ablation. Small 12(2016) 5936-5943.
76. Chengjun Chen, Shukun Li, Kai Liu, Guanghui Ma, Xuehai Yan*. Co-Assembly of Heparin and Polypeptide Hybrid Nanoparticles for Biomimetic Delivery and Anti-Thrombus Therapy. Small 12(2016) 4719-4725.
77. Xiaoyuan Ji, Zhiguo Su, Ping Wang, Guanghui Ma, Songping Zhang*. Integration of Artificial Photosynthesis System for Enhanced Electronic Energy-Transfer Efficacy: A Case Study for Solar-Energy Driven Bioconversion of Carbon Dioxide to Methanol. Small 12(2016) 4753-4762.
78. Ruiyun Zhang#, Ruirui Xing#, Tifeng Jiao*, Kai Ma, Chengjun Chen*, Guanghui Ma, Xuehai Yan*. Carrier-Free, Chemophotodynamic Dual Nanodrugs via Self-Assembly for Synergistic Antitumor Therapy. ACS Appl. Mater. Interf. 8(2016) 13262-13269.
79. Xiaoyuan Ji, Zhiguo Su, Mengfang Xu, Guanghui Ma, Songping Zhang*. TiO2-Horseradish Peroxidase Hybrid Catalyst Based on Hollow Nanofibers for Simultaneous Photochemical-Enzymatic Degradation of 2,4-Dichlorophenol. ACS Sustainable Chem. Eng. 4(2016) 3634-3640.
80. Yaqiong Li#, Xiunan Li#*, Chao Chen, Dawei Zhao, Zhiguo Su, Guanghui Ma, Rong Yu*. A rapid, non-invasive and non-destructive method for studying swelling behavior and microstructure variations of hydrogels. Carbohyd. Polym. 151(2016) 1251-1260.
81. Zhan Zhou, Jing Zhang*, Yan Zhang, Guanghui Ma, Zhiguo Su*. Specific Conjugation of the Hinge Region for Homogeneous Preparation of Antibody Fragment-Drug Conjugate: A Case Study for Doxorubicin-PEG-anti-CD20 Fab' Synthesis. Bioconjugate Chem. 27( 2016) 238-246.
82. Kai Liu, Yu Kang*, Guanghui Ma, Helmuth Moehwald, Xuehai Yan*. Molecular and mesoscale mechanism for hierarchical self-assembly of dipeptide and porphyrin light-harvesting system. Phys. Chem. Chem. Phys. 18(2016) 16738-16747.
83. Ruirui Xing, Tifeng Jiao*, Yamei Liu, Kai Ma, Qianli Zou*, Guanghui Ma, Xuehai Yan*. Co-Assembly of Graphene Oxide and Albumin/Photosensitizer Nanohybrids towards Enhanced Photodynamic Therapy. Polymers 8(2016) 181-191.
84. Anhe Wang, Yang Yang, Xuehai Yan, Guanghui Ma, Shuo Bai*, Junbai Li*. Preparation of multicompartment silica-gelatin nanoparticles with self-decomposability as drug containers for cancer therapy in vitro. RSC Adv. 6(2016) 70064-70071.
85. Kai Liu, Zhiguo Su, Shida Miao, Guanghui Ma, Songping Zhang*. Enzymatic waterborne polyurethane towards a robust and environmentally friendly antibiofouling coating. RSC Adv. 6(2016) 31698-31704.
86. Zenglan Li, Yan Zhang, Qi Wang, Zhengjun Li, Yongdong Liu, Songping Zhang, Guifeng Zhang, Guanghui Ma, Jian Luo*, Zhiguo Su*. Purification design and practice for pertactin, the third component of acellular pertussis vaccine, from Bordetella pertussis. Vaccine 34(2016) 4032-4039.
87. Kai Liu, Zhiguo Su, Shida Miao, Guanghui Ma, Songping Zhang*. UV-curable enzymatic antibacterial waterborne polyurethane coating. Biochem. Eng. J. 113(2016) 107-113.
88. Kai Liu, Shida Miao, Zhiguo Su, Lijing Sun, Guanghui Ma, Songping Zhang*. Castor oil-based waterborne polyurethanes with tunable properties and excellent biocompatibility. Eur. J. Lipid Sci. Technol. 118(2016) 1512-1520.
89. Enping Lai, Yuxia Wang*, Yi Wei, Guang Li*, Guanghui Ma. Covalent immobilization of trypsin onto thermo-sensitive poly(N-isopropylacrylamide-co-acrylic acid) microspheres with high activity and stability. J. Appl. Polym. Sci. 133(2016) 43343-43351.
90. Ruirui Xing, Tifeng Jiao*, Kai Ma, Guanghui Ma, Helmuth Mohwald, Xuehai Yan*. Regulating Cell Apoptosis on Layer-by-Layer Assembled Multilayers of Photosensitizer-Coupled Polypeptides and Gold Nanoparticles. Scientific Reports 6(2016) 26506.
2015
91. Qi Liu, Xiaoming Chen, Jilei Jia, Weifeng Zhang, Tingyuan Yang, Lianyan Wang*, Guanghui Ma*. pH-Responsive Poly(D,L-lactic-co-glycolic acid) Nanoparticles with Rapid Antigen Release Behavior Promote Immune Response. ACS Nano 9(2015) 4925-4938.
92. Yifeng Sheng, Guanqing Sun, Jie Wu, Guanghui Ma*, To Ngai*. Silica-Based Liquid Marbles as Microreactors for the Silver Mirror Reaction. Angew. Chem. Int. Ed. 54(2015) 7012-7017.
93. Dezhi Ni, Hui Ding, Shan Liu, Hua Yue, Yali Bao, Zhenhua Wang, Zhiguo Su, Wei Wei*, Guanghui Ma*. Superior Intratumoral Penetration of Paclitaxel Nanodots Strengthens Tumor Restriction and Metastasis Prevention. Small 11(2015) 2518-2526.
94. Nana Luo, Dezhi Ni, Hua Yue, Wei Wei*, Guanghui Ma*. Surface-Engineered Graphene Navigate Divergent Biological Outcomes toward Macrophages. ACS Appl. Mater. Interf. 7(2015) 5239-5247.
95. Qiang Fu#, Piping Lv#, Zhongke Chen, Dezhi Ni, Lijun Zhang, Hua Yue, Zhanguo Yue, Wei Wei*, GuangHui Ma*. Programmed Co-delivery of Paclitaxel and Doxorubicin Boosted by Camouflaging with Erythrocyte Membrane. Nanoscale 27(2015) 4020-4030.
96. Hua Yue#, Wei Wei#, Zonglin Gu#, Dezhi Ni, Nana Luo, Zaixing Yang, Lin Zhao, Jose Antonio Garate, Ruhong Zhou*, Zhiguo Su*, Guanghui Ma*. Exploration of graphene oxide as intelligent platform for cancer vaccine. Nanoscale 7(2015) 19949-19957.
97. Hui Ding, Yan-Lin Lv, De-Zhi Ni, Jie Wang, Zhi-Yuan Tian*, Wei Wei*, Guanghui Ma*. Erythrocyte membrane-coated biomimetic nanovectors with programmed delivery and near-infrared light triggering properties for photodynamic therapy of cancer. Nanoscale 7(2015) 9806-9815.
98. Yace Mi, Weiqing Zhou, Qiang Li, Fangling Gong, Rongyue Zhang*, Guanghui Ma*, Zhiguo Su. Preparation of water-in-oil emulsions using a hydrophobic polymer membrane with 3D bicontinuous skeleton structure. J. Membran. Sci. 490(2015) 113-119.
99. Xiaoqing Li, Qiang Li, Fangling Gong*, Jiandu Lei, Xi Zhao, Guanghui Ma*, Zhiguo Su. Preparation of large-sized highly uniform agarose beads by novel rotating membrane emulsification. J. Membran. Sci. 476 (2015) 30-39.
100. Feng Qi#, Liuqing Yang#, Jie Wu*, Guanghui Ma*, Zhiguo Su. Microcosmic Mechanism of Dication for Inhibiting Acylation of Acidic Peptide. Pharm. Res. 32(2015) 2310-2317.
101. Weifeng Zhang, Lianyan Wang, Tingyuan Yang, Yuan Liu, Xiaoming Chen, Qi Liu, Jilei Jia, Guanghui Ma*. Immunopotentiator-loaded polymeric microparticles as robust adjuvant to improve vaccine efficacy. Pharm. Res. 32(2015) 2837-2850.
102. Yace Mi, Weiqing Zhou, Qiang Li, Donglai Zhang, Rongyue Zhang*, Guanghui Ma*, Zhiguo Su. Detailed exploration of structure formation of an epoxy-based monolith with three-dimensional bicontinuous structure. RSC Adv. 68(2015) 55419-55427.
103. Hua Yue, Guanghui Ma*. Polymeric micro/nanoparticles: Particle design and potential vaccine delivery applications. Vaccine 33(2015) 5927-5936.
104. Yufei Xia, Qingze Fan, Dongxia Hao, Jie Wu*, Guanghui Ma*, Zhiguo Su. Chitosan-based mucosal adjuvants: Sunrise on the ocean. Vaccine 33(2015) 5997-6010.
105. Lianyan Wang, Tingyuan Yang, Guanghui Ma*. Particle design of Membrane Emulsification for protein drug and vaccine delivery. Curr. Pharm. Des. 21(2015) 2563-2598.
106. Jie Wu, Qingze Fan, Yufei Xia, Guanghui Ma*. Uniform-sized particles in biomedical field prepared by membrane emulsification technique. Chem. Eng. Sci. 125(2015) 85-97.
107. Lianyan Wang#*, Mingming Cai#, Yuan Liu, Tingyuan Yang, Yejing Zeng, Yueling Zhang, Qiang Li, Baocheng Zhu, Guanghui Ma*. Polymer hydrophobicity regulates paclitaxel distribution in microspheres, release profile and cytotoxicity in vitro. Powder Technol. 275(2015) 77-84.
108. Weichen Wang#, Weiqing Zhou#, Juan Li, Dongxia Hao, Zhiguo Su, Guanghui Ma*. Comparison of covalent and physical immobilization of lipase in gigaporous polymeric microspheres. Bioproc. Biosyst. Eng. 38(2015) 2107-2115.
109. Jian Qi, Xiaoyong Lai, Jiangyan Wang, Hongjie Tang, Hao Ren, Yu Yang, Quan Jin, Lijuan Zhang, Ranbo Yu*, Guanghui Ma, Zhiguo Su, Huijun Zhao, Dan Wang*. Multi-shelled hollow micro-nanostructures. Chem. Soc. Rev. 44(2015) 6749-6773.
110. Heng Deng, Fengying Dai, Guanghui Ma, Xin Zhang*. Theranostic Gold Nanomicelles made from Biocompatible Comb-like Polymers for Thermochemotherapy and Multifunctional Imaging with Rapid Clearance. Adv. Mater. 27(2015) 3645-3653.
111.Bingbing Hu, Fengying Dai, Zhanming Fan, Guanghui Ma, Qunwei Tang*, Xin Zhang*. Nanotheranostics: Congo Red/Rutin-MNPs with Enhanced Magnetic Resonance Imaging and H2O2-Responsive Therapy of Alzheimer's Disease in APPswe/PS1dE9 Transgenic Mice. Adv. Mater. 27(2015) 5499-5505.
112.Xiaoyuan Ji, Zhiguo Su, Ping Wang, Guanghui Ma, Songping Zhang*. Tethering of nicotinamide adenine dinucleotide inside hollow nanofibers for high-yield synthesis of methanol from carbon dioxide catalyzed by coencapsulated multienzymes. ACS Nano 9(2015) 4600-4610.
113.Kai Liu, Ruirui Xing, Chengjun Chen, Guizhi Shen, Linyin Yan, Qianli Zou, Guanghui Ma, Helmuth Mohwald, Xuehai Yan*. Peptide-Induced Hierarchical Long-Range Order and Photocatalytic Activity of Porphyrin Assemblies. Angew.Chem. Int. Ed. 54(2015) 500-505.
114.Yan Li#, Ruiyuan Liu#, Jun Yang, Yuanjie Shi, Guanghui Ma, Zhenzhong Zhang*, Xin Zhang*. Enhanced retention and anti-tumor efficacy of liposomes by changing their cellular uptake and pharmacokinetics behavior. Biomaterials 41(2015) 1-14.
115.Ruirui Xing, Tifeng Jiao*, Linyin Yan, Guanghui Ma, Lei Liu*, Luru Dai Junbai Li, Helmuth Möhwald, Xuehai Yan*. Colloidal Gold-Collagen Protein Core-Shell Nanoconjugate: One-Step Biomimetic Synthesis, Layer-by-Layer Assembled Film, and Controlled Cell Growth. ACS Appl. Mater. Interf. 7(2015) 24733-24740.
116.Yanli Yang, Mengran Yu, Songping Zhang*, Guanghui Ma, Zhiguo Su*. Adsorption of virus-like particles on ion exchange surface: conformational changes at different pH detected by dual polarization interferometry. J. Chromatogr. A 1408(2015) 161-168.
117.Mengran Yu, Songping Zhang*, Yan Zhang, Yanli Yang, Guanghui Ma, Zhiguo Su*. Microcalorimetric study of adsorption and disassembling of virus-like particles on anion exchange chromatography media. J. Chromatogr. A 1388(2015) 195-206.
118.Rongyue Zhang*, Qiang Li, Yongdong Huang, Lan Zhao, Peili Ye, Guanghui Ma, Zhiguo Su. Preparation of PEGA grafted poly(chloromethylstyrene-co-ethylene glycol dimethacrylate) monolith for high-efficiency solid phase peptide synthesis under continuous flow techniques. Polymer 61( 2015) 115-122.
119.Yanli Yang#, Hao Li#, Zhengjun Li, Yan Zhang, Songping Zhang*, Yi Chen, Mengran Yu, Guanghui Ma, Zhiguo Su*. Size-exclusion HPLC provides a simple, rapid, and versatile alternative method for quality control of vaccines by characterizing the assembly of antigens. Vaccine 33(2015) 1143-1150.
120.Yi Chen#, Yan Zhang#, Can Quan, Jian Luo, Yanli Yang, Mengran Yu, Yingjun Kong, Guanghui Ma, Zhiguo Su*. Aggregation and antigenicity of virus like particle in salt solution—A case study with hepatitis B surface antigen. Vaccine 33(2015) 4300-4306.
121.Yan Zhang, Jian Luo, Songping Zhang*, Qian Bai, Zenglan Li, Qiang Li, Yongdong Liu, Guifeng Zhang, Guanghui Ma, Zhiguo Su*. Selection of downstream steps by analysis of protein surface property: A case study for recombinant human lactoferrin purification from milk of transgenic cow. Process Biochem. 50(2015) 1441-1448.
122.Lijing Sun#, Zhidong Xiong#, Weiqing Zhou, Ruina Liu, Xingran Yan, Juan Li, Wenqi An, Guoqiang Yuan, Guanghui Ma, Zhiguo Su*. Novel konjac glucomannan microcarriers for anchorage-dependent animal cell culture. Biochem. Eng. J. 96(2015) 46-54.
123.Qingqing Wang, Tao Hu, Lijing Sun, Shaoyang Ji, Dawei Zhao, Jiaxin Liu, Guanghui Ma, Zhiguo Su*. CO binding improves the structural, functional, physical and anti-oxidation properties of the PEGylated hemoglobin. Artif. Cell. Nanomed. B. 43(2015) 18-25.
124.Xiunan Li*, Yaqiong Li, Chao Chen, Dawei Zhao, Xiaojun Wang, Lan Zhao, Hong Shi. Guanghui Ma, Zhiguo Su*. Pore size analysis from low field NMR spin-spin relaxation measurements of porous microspheres. J. Porous Mat. 22(2015) 11-20.
125.Hao Li#, Yanli Yang#, Yan Zhang, Songping Zhang, Qizu Zhao, Yuanyuan Zhu, Xingqi Zou,Mengran Yu, Guanghui Ma, Zhiguo Su*. A hydrophobic interaction chromatography strategy for purification of inactivated foot and mouth disease virus. Protein Expres. Purif. 113(2015) 23-29.
126.Chenxu Zhang#, Rongyue Zhang, Qiang Li#*, Yongdong Huang, Lan Zhao, Zhiguo Su, Fangling Gong, Zheng Lv, Honghyan Song, Wei Li, Qipeng Yuan, Guanghui Ma. Rapid octreotide separation from synthetic peptide crude mixtures by chromatography on poly(styrene-co-divinylbenzene)-based reversed phases. Sep. Purif. Technol. 154(2015) 351-358.
127.Nani Wibowo, Linda Lua, Alois Jungbauer, Guanghui Ma. Vaccine Engineering. Vaccine 33(2015) 5889.
128.Kai Liu, Songping Zhang*, Zhiguo Su, Guanghui Ma. Preparation and characterization of castor oil-based cationic waterborne polyurethane. Adv. Mater. Res. 1090(2015) 3-7.
Patents
Preparation of Polysaccharide Beads | US8137563 JP5457335 ZL200710098700.9 |
A Super Macroporous Polymeric Microsphere and Preparation Process Thereof | EP2088160 US8940172 ZL200510087138.0 |
Uniformly Sized Agarose Gel Microsphere and Preparation Method Thereof | ZL200410000087.9 |
Membrane Emulsifier and Preparation Method of Emulsion | ZL200810223283.0 |
Method for preparing polymer microsphere or microcapsule carrier embedded hydrophilic drug with uniform size | ZL200310100214.8 |
Fluorescent microsphere and preparation method and application thereof | US 8460638 B2 ZL200610152191.9 |
Students
已指导学生
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